Amino acid dipepetide frequency for Allisonella histaminiformans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.031AlaAla: 9.031 ± 0.205
1.157AlaCys: 1.157 ± 0.052
4.904AlaAsp: 4.904 ± 0.111
5.993AlaGlu: 5.993 ± 0.122
3.26AlaPhe: 3.26 ± 0.092
7.234AlaGly: 7.234 ± 0.128
1.747AlaHis: 1.747 ± 0.054
5.412AlaIle: 5.412 ± 0.114
3.984AlaLys: 3.984 ± 0.118
8.179AlaLeu: 8.179 ± 0.136
2.786AlaMet: 2.786 ± 0.077
2.452AlaAsn: 2.452 ± 0.072
2.677AlaPro: 2.677 ± 0.089
2.595AlaGln: 2.595 ± 0.086
4.608AlaArg: 4.608 ± 0.116
4.872AlaSer: 4.872 ± 0.118
3.162AlaThr: 3.162 ± 0.085
7.184AlaVal: 7.184 ± 0.161
0.84AlaTrp: 0.84 ± 0.042
2.702AlaTyr: 2.702 ± 0.07
0.0AlaXaa: 0.0 ± 0.0
Cys
0.966CysAla: 0.966 ± 0.045
0.195CysCys: 0.195 ± 0.019
0.611CysAsp: 0.611 ± 0.039
0.592CysGlu: 0.592 ± 0.039
0.594CysPhe: 0.594 ± 0.038
1.228CysGly: 1.228 ± 0.054
0.42CysHis: 0.42 ± 0.032
0.857CysIle: 0.857 ± 0.047
0.458CysLys: 0.458 ± 0.038
1.157CysLeu: 1.157 ± 0.054
0.401CysMet: 0.401 ± 0.028
0.388CysAsn: 0.388 ± 0.03
0.563CysPro: 0.563 ± 0.034
0.378CysGln: 0.378 ± 0.029
0.812CysArg: 0.812 ± 0.044
0.697CysSer: 0.697 ± 0.04
0.686CysThr: 0.686 ± 0.035
0.756CysVal: 0.756 ± 0.04
0.122CysTrp: 0.122 ± 0.017
0.466CysTyr: 0.466 ± 0.033
0.0CysXaa: 0.0 ± 0.0
Asp
4.266AspAla: 4.266 ± 0.12
0.682AspCys: 0.682 ± 0.038
2.912AspAsp: 2.912 ± 0.084
3.772AspGlu: 3.772 ± 0.097
2.559AspPhe: 2.559 ± 0.079
4.125AspGly: 4.125 ± 0.089
1.096AspHis: 1.096 ± 0.049
4.194AspIle: 4.194 ± 0.099
3.401AspLys: 3.401 ± 0.079
4.112AspLeu: 4.112 ± 0.105
2.145AspMet: 2.145 ± 0.067
2.112AspAsn: 2.112 ± 0.077
1.822AspPro: 1.822 ± 0.063
1.348AspGln: 1.348 ± 0.06
2.832AspArg: 2.832 ± 0.084
3.218AspSer: 3.218 ± 0.091
3.054AspThr: 3.054 ± 0.085
4.045AspVal: 4.045 ± 0.103
0.628AspTrp: 0.628 ± 0.038
2.208AspTyr: 2.208 ± 0.072
0.0AspXaa: 0.0 ± 0.0
Glu
5.998GluAla: 5.998 ± 0.148
0.554GluCys: 0.554 ± 0.037
3.749GluAsp: 3.749 ± 0.091
5.966GluGlu: 5.966 ± 0.142
2.133GluPhe: 2.133 ± 0.058
4.513GluGly: 4.513 ± 0.1
1.493GluHis: 1.493 ± 0.061
4.421GluIle: 4.421 ± 0.102
5.836GluLys: 5.836 ± 0.136
5.563GluLeu: 5.563 ± 0.126
2.297GluMet: 2.297 ± 0.069
3.012GluAsn: 3.012 ± 0.082
1.797GluPro: 1.797 ± 0.064
2.481GluGln: 2.481 ± 0.088
3.361GluArg: 3.361 ± 0.096
3.191GluSer: 3.191 ± 0.096
3.199GluThr: 3.199 ± 0.082
4.018GluVal: 4.018 ± 0.103
0.674GluTrp: 0.674 ± 0.042
2.11GluTyr: 2.11 ± 0.074
0.0GluXaa: 0.0 ± 0.0
Phe
2.91PheAla: 2.91 ± 0.082
0.674PheCys: 0.674 ± 0.037
2.024PheAsp: 2.024 ± 0.063
1.906PheGlu: 1.906 ± 0.071
1.999PhePhe: 1.999 ± 0.079
3.021PheGly: 3.021 ± 0.092
1.115PheHis: 1.115 ± 0.051
3.075PheIle: 3.075 ± 0.096
1.711PheLys: 1.711 ± 0.066
3.869PheLeu: 3.869 ± 0.122
1.413PheMet: 1.413 ± 0.062
1.49PheAsn: 1.49 ± 0.061
1.577PhePro: 1.577 ± 0.057
1.05PheGln: 1.05 ± 0.05
2.066PheArg: 2.066 ± 0.066
2.929PheSer: 2.929 ± 0.082
2.628PheThr: 2.628 ± 0.071
2.458PheVal: 2.458 ± 0.078
0.472PheTrp: 0.472 ± 0.035
1.509PheTyr: 1.509 ± 0.062
0.0PheXaa: 0.0 ± 0.0
Gly
5.857GlyAla: 5.857 ± 0.147
1.016GlyCys: 1.016 ± 0.046
3.854GlyAsp: 3.854 ± 0.099
4.532GlyGlu: 4.532 ± 0.09
3.04GlyPhe: 3.04 ± 0.084
5.282GlyGly: 5.282 ± 0.127
1.917GlyHis: 1.917 ± 0.061
6.172GlyIle: 6.172 ± 0.134
5.571GlyLys: 5.571 ± 0.107
6.573GlyLeu: 6.573 ± 0.114
2.639GlyMet: 2.639 ± 0.071
3.075GlyAsn: 3.075 ± 0.092
1.923GlyPro: 1.923 ± 0.068
2.433GlyGln: 2.433 ± 0.084
4.102GlyArg: 4.102 ± 0.109
4.085GlySer: 4.085 ± 0.105
4.618GlyThr: 4.618 ± 0.128
5.345GlyVal: 5.345 ± 0.121
0.758GlyTrp: 0.758 ± 0.039
2.981GlyTyr: 2.981 ± 0.078
0.0GlyXaa: 0.0 ± 0.0
His
1.768HisAla: 1.768 ± 0.071
0.306HisCys: 0.306 ± 0.029
1.173HisAsp: 1.173 ± 0.049
1.251HisGlu: 1.251 ± 0.054
1.05HisPhe: 1.05 ± 0.042
1.961HisGly: 1.961 ± 0.067
0.655HisHis: 0.655 ± 0.038
1.833HisIle: 1.833 ± 0.071
1.306HisLys: 1.306 ± 0.057
2.297HisLeu: 2.297 ± 0.073
0.903HisMet: 0.903 ± 0.047
0.924HisAsn: 0.924 ± 0.045
1.302HisPro: 1.302 ± 0.051
0.697HisGln: 0.697 ± 0.039
1.207HisArg: 1.207 ± 0.05
1.209HisSer: 1.209 ± 0.051
1.323HisThr: 1.323 ± 0.054
1.807HisVal: 1.807 ± 0.073
0.262HisTrp: 0.262 ± 0.022
0.854HisTyr: 0.854 ± 0.04
0.0HisXaa: 0.0 ± 0.0
Ile
5.733IleAla: 5.733 ± 0.134
1.037IleCys: 1.037 ± 0.053
3.489IleAsp: 3.489 ± 0.093
3.508IleGlu: 3.508 ± 0.094
2.46IlePhe: 2.46 ± 0.085
5.013IleGly: 5.013 ± 0.116
2.051IleHis: 2.051 ± 0.075
4.717IleIle: 4.717 ± 0.117
3.332IleLys: 3.332 ± 0.095
6.774IleLeu: 6.774 ± 0.14
1.91IleMet: 1.91 ± 0.07
2.628IleAsn: 2.628 ± 0.074
3.764IlePro: 3.764 ± 0.093
2.211IleGln: 2.211 ± 0.07
4.096IleArg: 4.096 ± 0.1
4.694IleSer: 4.694 ± 0.107
4.173IleThr: 4.173 ± 0.102
4.478IleVal: 4.478 ± 0.109
0.644IleTrp: 0.644 ± 0.041
2.288IleTyr: 2.288 ± 0.07
0.0IleXaa: 0.0 ± 0.0
Lys
5.555LysAla: 5.555 ± 0.139
0.498LysCys: 0.498 ± 0.034
3.67LysAsp: 3.67 ± 0.1
5.236LysGlu: 5.236 ± 0.121
1.444LysPhe: 1.444 ± 0.063
4.188LysGly: 4.188 ± 0.097
1.232LysHis: 1.232 ± 0.053
3.903LysIle: 3.903 ± 0.103
5.139LysLys: 5.139 ± 0.13
4.574LysLeu: 4.574 ± 0.093
2.047LysMet: 2.047 ± 0.066
2.777LysAsn: 2.777 ± 0.083
2.02LysPro: 2.02 ± 0.067
2.25LysGln: 2.25 ± 0.071
2.985LysArg: 2.985 ± 0.088
2.882LysSer: 2.882 ± 0.083
3.185LysThr: 3.185 ± 0.092
3.993LysVal: 3.993 ± 0.109
0.569LysTrp: 0.569 ± 0.034
1.933LysTyr: 1.933 ± 0.066
0.0LysXaa: 0.0 ± 0.0
Leu
8.378LeuAla: 8.378 ± 0.132
1.318LeuCys: 1.318 ± 0.062
4.753LeuAsp: 4.753 ± 0.108
5.133LeuGlu: 5.133 ± 0.118
3.938LeuPhe: 3.938 ± 0.113
6.6LeuGly: 6.6 ± 0.131
2.183LeuHis: 2.183 ± 0.086
5.706LeuIle: 5.706 ± 0.124
5.345LeuLys: 5.345 ± 0.123
8.536LeuLeu: 8.536 ± 0.201
2.725LeuMet: 2.725 ± 0.083
3.187LeuAsn: 3.187 ± 0.081
4.058LeuPro: 4.058 ± 0.098
2.761LeuGln: 2.761 ± 0.087
4.251LeuArg: 4.251 ± 0.103
6.266LeuSer: 6.266 ± 0.131
5.481LeuThr: 5.481 ± 0.121
5.859LeuVal: 5.859 ± 0.134
0.928LeuTrp: 0.928 ± 0.051
3.248LeuTyr: 3.248 ± 0.089
0.0LeuXaa: 0.0 ± 0.0
Met
3.243MetAla: 3.243 ± 0.098
0.283MetCys: 0.283 ± 0.023
1.965MetAsp: 1.965 ± 0.067
2.433MetGlu: 2.433 ± 0.072
0.961MetPhe: 0.961 ± 0.041
2.586MetGly: 2.586 ± 0.079
0.749MetHis: 0.749 ± 0.041
1.902MetIle: 1.902 ± 0.058
2.557MetLys: 2.557 ± 0.072
2.63MetLeu: 2.63 ± 0.081
0.903MetMet: 0.903 ± 0.047
1.6MetAsn: 1.6 ± 0.061
1.278MetPro: 1.278 ± 0.05
1.161MetGln: 1.161 ± 0.051
1.518MetArg: 1.518 ± 0.054
1.791MetSer: 1.791 ± 0.062
1.971MetThr: 1.971 ± 0.063
2.156MetVal: 2.156 ± 0.068
0.197MetTrp: 0.197 ± 0.02
0.936MetTyr: 0.936 ± 0.044
0.0MetXaa: 0.0 ± 0.0
Asn
3.002AsnAla: 3.002 ± 0.084
0.386AsnCys: 0.386 ± 0.027
1.952AsnAsp: 1.952 ± 0.067
2.259AsnGlu: 2.259 ± 0.074
1.289AsnPhe: 1.289 ± 0.053
2.973AsnGly: 2.973 ± 0.1
1.092AsnHis: 1.092 ± 0.053
2.614AsnIle: 2.614 ± 0.072
2.225AsnLys: 2.225 ± 0.067
3.565AsnLeu: 3.565 ± 0.086
1.222AsnMet: 1.222 ± 0.056
1.411AsnAsn: 1.411 ± 0.058
2.152AsnPro: 2.152 ± 0.062
1.383AsnGln: 1.383 ± 0.056
2.244AsnArg: 2.244 ± 0.077
1.952AsnSer: 1.952 ± 0.066
1.978AsnThr: 1.978 ± 0.062
2.509AsnVal: 2.509 ± 0.087
0.426AsnTrp: 0.426 ± 0.033
1.314AsnTyr: 1.314 ± 0.057
0.0AsnXaa: 0.0 ± 0.0
Pro
3.287ProAla: 3.287 ± 0.109
0.456ProCys: 0.456 ± 0.033
2.601ProAsp: 2.601 ± 0.069
3.816ProGlu: 3.816 ± 0.09
1.891ProPhe: 1.891 ± 0.056
3.033ProGly: 3.033 ± 0.079
0.806ProHis: 0.806 ± 0.039
2.061ProIle: 2.061 ± 0.071
1.711ProLys: 1.711 ± 0.066
3.531ProLeu: 3.531 ± 0.093
1.138ProMet: 1.138 ± 0.053
1.075ProAsn: 1.075 ± 0.05
0.903ProPro: 0.903 ± 0.047
1.224ProGln: 1.224 ± 0.046
1.377ProArg: 1.377 ± 0.051
2.152ProSer: 2.152 ± 0.081
1.325ProThr: 1.325 ± 0.05
4.039ProVal: 4.039 ± 0.085
0.5ProTrp: 0.5 ± 0.034
1.516ProTyr: 1.516 ± 0.058
0.0ProXaa: 0.0 ± 0.0
Gln
3.052GlnAla: 3.052 ± 0.086
0.302GlnCys: 0.302 ± 0.026
1.572GlnAsp: 1.572 ± 0.063
2.372GlnGlu: 2.372 ± 0.083
1.23GlnPhe: 1.23 ± 0.048
2.33GlnGly: 2.33 ± 0.075
0.705GlnHis: 0.705 ± 0.037
2.33GlnIle: 2.33 ± 0.066
2.263GlnLys: 2.263 ± 0.071
2.794GlnLeu: 2.794 ± 0.078
1.161GlnMet: 1.161 ± 0.049
1.278GlnAsn: 1.278 ± 0.056
1.092GlnPro: 1.092 ± 0.042
1.344GlnGln: 1.344 ± 0.063
1.595GlnArg: 1.595 ± 0.055
1.604GlnSer: 1.604 ± 0.06
1.545GlnThr: 1.545 ± 0.055
2.414GlnVal: 2.414 ± 0.077
0.443GlnTrp: 0.443 ± 0.032
1.159GlnTyr: 1.159 ± 0.051
0.0GlnXaa: 0.0 ± 0.0
Arg
3.569ArgAla: 3.569 ± 0.09
0.544ArgCys: 0.544 ± 0.033
2.633ArgAsp: 2.633 ± 0.065
4.008ArgGlu: 4.008 ± 0.105
2.177ArgPhe: 2.177 ± 0.067
3.292ArgGly: 3.292 ± 0.086
1.251ArgHis: 1.251 ± 0.047
3.884ArgIle: 3.884 ± 0.094
4.167ArgLys: 4.167 ± 0.097
4.822ArgLeu: 4.822 ± 0.113
1.973ArgMet: 1.973 ± 0.076
2.391ArgAsn: 2.391 ± 0.074
1.841ArgPro: 1.841 ± 0.059
2.286ArgGln: 2.286 ± 0.071
3.201ArgArg: 3.201 ± 0.105
2.391ArgSer: 2.391 ± 0.08
2.612ArgThr: 2.612 ± 0.077
3.197ArgVal: 3.197 ± 0.08
0.607ArgTrp: 0.607 ± 0.032
1.889ArgTyr: 1.889 ± 0.066
0.0ArgXaa: 0.0 ± 0.0
Ser
4.587SerAla: 4.587 ± 0.099
0.728SerCys: 0.728 ± 0.04
3.044SerAsp: 3.044 ± 0.079
3.254SerGlu: 3.254 ± 0.086
2.763SerPhe: 2.763 ± 0.071
5.11SerGly: 5.11 ± 0.126
1.57SerHis: 1.57 ± 0.062
3.812SerIle: 3.812 ± 0.091
2.213SerLys: 2.213 ± 0.075
5.658SerLeu: 5.658 ± 0.116
1.929SerMet: 1.929 ± 0.067
1.789SerAsn: 1.789 ± 0.062
2.309SerPro: 2.309 ± 0.076
1.908SerGln: 1.908 ± 0.058
3.512SerArg: 3.512 ± 0.097
3.531SerSer: 3.531 ± 0.098
2.691SerThr: 2.691 ± 0.072
4.325SerVal: 4.325 ± 0.099
0.733SerTrp: 0.733 ± 0.04
2.175SerTyr: 2.175 ± 0.075
0.0SerXaa: 0.0 ± 0.0
Thr
4.847ThrAla: 4.847 ± 0.123
0.632ThrCys: 0.632 ± 0.037
2.962ThrAsp: 2.962 ± 0.076
3.43ThrGlu: 3.43 ± 0.091
1.971ThrPhe: 1.971 ± 0.061
5.019ThrGly: 5.019 ± 0.104
1.115ThrHis: 1.115 ± 0.045
3.617ThrIle: 3.617 ± 0.087
2.292ThrLys: 2.292 ± 0.082
5.059ThrLeu: 5.059 ± 0.1
1.539ThrMet: 1.539 ± 0.052
1.631ThrAsn: 1.631 ± 0.061
2.496ThrPro: 2.496 ± 0.063
1.356ThrGln: 1.356 ± 0.06
2.771ThrArg: 2.771 ± 0.091
2.767ThrSer: 2.767 ± 0.084
2.599ThrThr: 2.599 ± 0.074
4.327ThrVal: 4.327 ± 0.104
0.594ThrTrp: 0.594 ± 0.038
1.873ThrTyr: 1.873 ± 0.067
0.0ThrXaa: 0.0 ± 0.0
Val
5.225ValAla: 5.225 ± 0.118
0.978ValCys: 0.978 ± 0.05
3.816ValAsp: 3.816 ± 0.089
4.274ValGlu: 4.274 ± 0.122
2.949ValPhe: 2.949 ± 0.086
4.28ValGly: 4.28 ± 0.111
1.694ValHis: 1.694 ± 0.053
5.305ValIle: 5.305 ± 0.117
4.068ValLys: 4.068 ± 0.113
6.896ValLeu: 6.896 ± 0.117
2.185ValMet: 2.185 ± 0.078
2.819ValAsn: 2.819 ± 0.082
3.149ValPro: 3.149 ± 0.073
2.169ValGln: 2.169 ± 0.069
3.594ValArg: 3.594 ± 0.088
4.942ValSer: 4.942 ± 0.102
4.245ValThr: 4.245 ± 0.099
5.299ValVal: 5.299 ± 0.123
0.731ValTrp: 0.731 ± 0.042
2.626ValTyr: 2.626 ± 0.07
0.0ValXaa: 0.0 ± 0.0
Trp
0.752TrpAla: 0.752 ± 0.043
0.139TrpCys: 0.139 ± 0.018
0.573TrpAsp: 0.573 ± 0.036
0.577TrpGlu: 0.577 ± 0.037
0.519TrpPhe: 0.519 ± 0.034
0.865TrpGly: 0.865 ± 0.052
0.304TrpHis: 0.304 ± 0.026
0.84TrpIle: 0.84 ± 0.045
0.861TrpLys: 0.861 ± 0.038
0.932TrpLeu: 0.932 ± 0.046
0.407TrpMet: 0.407 ± 0.031
0.609TrpAsn: 0.609 ± 0.038
0.319TrpPro: 0.319 ± 0.027
0.439TrpGln: 0.439 ± 0.03
0.47TrpArg: 0.47 ± 0.033
0.542TrpSer: 0.542 ± 0.032
0.449TrpThr: 0.449 ± 0.026
0.521TrpVal: 0.521 ± 0.032
0.126TrpTrp: 0.126 ± 0.016
0.378TrpTyr: 0.378 ± 0.033
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.752TyrAla: 2.752 ± 0.093
0.46TyrCys: 0.46 ± 0.027
2.276TyrAsp: 2.276 ± 0.082
2.053TyrGlu: 2.053 ± 0.07
1.667TyrPhe: 1.667 ± 0.062
3.12TyrGly: 3.12 ± 0.07
0.892TyrHis: 0.892 ± 0.05
2.347TyrIle: 2.347 ± 0.062
1.64TyrLys: 1.64 ± 0.058
3.132TyrLeu: 3.132 ± 0.08
1.098TyrMet: 1.098 ± 0.043
1.297TyrAsn: 1.297 ± 0.062
1.402TyrPro: 1.402 ± 0.048
1.115TyrGln: 1.115 ± 0.044
2.131TyrArg: 2.131 ± 0.074
1.925TyrSer: 1.925 ± 0.058
1.973TyrThr: 1.973 ± 0.069
2.519TyrVal: 2.519 ± 0.074
0.367TyrTrp: 0.367 ± 0.03
1.386TyrTyr: 1.386 ± 0.068
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1536 proteins (476354 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski