Amino acid dipepetide frequency for Solibacillus silvestris (strain StLB046) (Bacillus silvestris)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.314AlaAla: 6.314 ± 0.096	0.583AlaCys: 0.583 ± 0.025	3.572AlaAsp: 3.572 ± 0.063	4.926AlaGlu: 4.926 ± 0.08	3.416AlaPhe: 3.416 ± 0.057	5.37AlaGly: 5.37 ± 0.087	1.353AlaHis: 1.353 ± 0.033	6.725AlaIle: 6.725 ± 0.097	5.011AlaLys: 5.011 ± 0.075	7.675AlaLeu: 7.675 ± 0.096	2.208AlaMet: 2.208 ± 0.048	3.267AlaAsn: 3.267 ± 0.055	2.24AlaPro: 2.24 ± 0.046	2.841AlaGln: 2.841 ± 0.055	2.697AlaArg: 2.697 ± 0.056	4.119AlaSer: 4.119 ± 0.066	4.155AlaThr: 4.155 ± 0.066	5.74AlaVal: 5.74 ± 0.078	0.572AlaTrp: 0.572 ± 0.022	2.432AlaTyr: 2.432 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	0.483CysAla: 0.483 ± 0.024	0.086CysCys: 0.086 ± 0.011	0.352CysAsp: 0.352 ± 0.018	0.452CysGlu: 0.452 ± 0.022	0.319CysPhe: 0.319 ± 0.016	0.627CysGly: 0.627 ± 0.025	0.154CysHis: 0.154 ± 0.012	0.56CysIle: 0.56 ± 0.024	0.323CysLys: 0.323 ± 0.02	0.562CysLeu: 0.562 ± 0.022	0.15CysMet: 0.15 ± 0.012	0.276CysAsn: 0.276 ± 0.015	0.304CysPro: 0.304 ± 0.017	0.192CysGln: 0.192 ± 0.013	0.242CysArg: 0.242 ± 0.016	0.463CysSer: 0.463 ± 0.019	0.399CysThr: 0.399 ± 0.018	0.398CysVal: 0.398 ± 0.02	0.071CysTrp: 0.071 ± 0.009	0.275CysTyr: 0.275 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.682AspAla: 3.682 ± 0.071	0.346AspCys: 0.346 ± 0.018	2.395AspAsp: 2.395 ± 0.057	4.662AspGlu: 4.662 ± 0.071	2.503AspPhe: 2.503 ± 0.052	3.428AspGly: 3.428 ± 0.062	0.999AspHis: 0.999 ± 0.033	3.938AspIle: 3.938 ± 0.061	2.79AspLys: 2.79 ± 0.063	4.782AspLeu: 4.782 ± 0.065	1.25AspMet: 1.25 ± 0.031	1.918AspAsn: 1.918 ± 0.043	1.684AspPro: 1.684 ± 0.037	1.739AspGln: 1.739 ± 0.047	2.011AspArg: 2.011 ± 0.045	2.422AspSer: 2.422 ± 0.052	2.448AspThr: 2.448 ± 0.05	3.801AspVal: 3.801 ± 0.064	0.547AspTrp: 0.547 ± 0.021	2.243AspTyr: 2.243 ± 0.05	0.0AspXaa: 0.0 ± 0.0
Glu	5.72GluAla: 5.72 ± 0.078	0.358GluCys: 0.358 ± 0.02	3.724GluAsp: 3.724 ± 0.062	6.85GluGlu: 6.85 ± 0.1	2.667GluPhe: 2.667 ± 0.056	4.151GluGly: 4.151 ± 0.063	1.643GluHis: 1.643 ± 0.042	5.763GluIle: 5.763 ± 0.074	6.103GluLys: 6.103 ± 0.093	7.182GluLeu: 7.182 ± 0.093	2.386GluMet: 2.386 ± 0.05	3.978GluAsn: 3.978 ± 0.061	1.995GluPro: 1.995 ± 0.045	4.541GluGln: 4.541 ± 0.072	3.485GluArg: 3.485 ± 0.061	3.378GluSer: 3.378 ± 0.059	4.033GluThr: 4.033 ± 0.064	5.401GluVal: 5.401 ± 0.086	0.732GluTrp: 0.732 ± 0.026	2.215GluTyr: 2.215 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.45PheAla: 3.45 ± 0.065	0.359PheCys: 0.359 ± 0.017	2.479PheAsp: 2.479 ± 0.048	3.289PheGlu: 3.289 ± 0.052	2.225PhePhe: 2.225 ± 0.065	3.294PheGly: 3.294 ± 0.052	0.887PheHis: 0.887 ± 0.031	4.226PheIle: 4.226 ± 0.082	2.591PheLys: 2.591 ± 0.047	4.257PheLeu: 4.257 ± 0.068	1.246PheMet: 1.246 ± 0.036	2.142PheAsn: 2.142 ± 0.047	1.557PhePro: 1.557 ± 0.04	1.475PheGln: 1.475 ± 0.038	1.39PheArg: 1.39 ± 0.039	3.014PheSer: 3.014 ± 0.055	2.911PheThr: 2.911 ± 0.056	3.288PheVal: 3.288 ± 0.063	0.456PheTrp: 0.456 ± 0.025	1.739PheTyr: 1.739 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	4.988GlyAla: 4.988 ± 0.074	0.556GlyCys: 0.556 ± 0.023	3.057GlyAsp: 3.057 ± 0.065	4.584GlyGlu: 4.584 ± 0.064	3.294GlyPhe: 3.294 ± 0.06	4.637GlyGly: 4.637 ± 0.077	1.365GlyHis: 1.365 ± 0.036	5.797GlyIle: 5.797 ± 0.083	4.604GlyLys: 4.604 ± 0.071	6.132GlyLeu: 6.132 ± 0.083	2.019GlyMet: 2.019 ± 0.047	2.719GlyAsn: 2.719 ± 0.062	1.586GlyPro: 1.586 ± 0.039	2.299GlyGln: 2.299 ± 0.049	2.448GlyArg: 2.448 ± 0.049	3.688GlySer: 3.688 ± 0.052	4.009GlyThr: 4.009 ± 0.065	4.851GlyVal: 4.851 ± 0.078	0.71GlyTrp: 0.71 ± 0.03	2.723GlyTyr: 2.723 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.397HisAla: 1.397 ± 0.037	0.193HisCys: 0.193 ± 0.014	0.947HisAsp: 0.947 ± 0.028	1.471HisGlu: 1.471 ± 0.037	1.105HisPhe: 1.105 ± 0.04	1.308HisGly: 1.308 ± 0.039	0.6HisHis: 0.6 ± 0.029	1.608HisIle: 1.608 ± 0.044	0.946HisLys: 0.946 ± 0.032	2.054HisLeu: 2.054 ± 0.042	0.467HisMet: 0.467 ± 0.021	0.791HisAsn: 0.791 ± 0.029	1.038HisPro: 1.038 ± 0.032	0.793HisGln: 0.793 ± 0.029	0.786HisArg: 0.786 ± 0.027	1.1HisSer: 1.1 ± 0.037	1.095HisThr: 1.095 ± 0.028	1.319HisVal: 1.319 ± 0.038	0.187HisTrp: 0.187 ± 0.013	0.948HisTyr: 0.948 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.819IleAla: 6.819 ± 0.096	0.611IleCys: 0.611 ± 0.024	4.389IleAsp: 4.389 ± 0.059	6.386IleGlu: 6.386 ± 0.078	3.487IlePhe: 3.487 ± 0.071	5.979IleGly: 5.979 ± 0.084	1.629IleHis: 1.629 ± 0.039	6.446IleIle: 6.446 ± 0.107	4.206IleLys: 4.206 ± 0.062	7.352IleLeu: 7.352 ± 0.096	1.884IleMet: 1.884 ± 0.046	3.33IleAsn: 3.33 ± 0.068	3.289IlePro: 3.289 ± 0.057	3.066IleGln: 3.066 ± 0.057	3.094IleArg: 3.094 ± 0.053	5.033IleSer: 5.033 ± 0.079	4.545IleThr: 4.545 ± 0.071	6.224IleVal: 6.224 ± 0.097	0.656IleTrp: 0.656 ± 0.028	2.59IleTyr: 2.59 ± 0.047	0.0IleXaa: 0.0 ± 0.0
Lys	4.469LysAla: 4.469 ± 0.075	0.324LysCys: 0.324 ± 0.018	3.382LysAsp: 3.382 ± 0.055	6.022LysGlu: 6.022 ± 0.09	2.229LysPhe: 2.229 ± 0.044	3.998LysGly: 3.998 ± 0.061	1.181LysHis: 1.181 ± 0.035	4.71LysIle: 4.71 ± 0.067	5.078LysLys: 5.078 ± 0.09	5.803LysLeu: 5.803 ± 0.085	2.338LysMet: 2.338 ± 0.049	3.372LysAsn: 3.372 ± 0.056	2.119LysPro: 2.119 ± 0.052	3.127LysGln: 3.127 ± 0.059	2.892LysArg: 2.892 ± 0.05	3.451LysSer: 3.451 ± 0.056	3.526LysThr: 3.526 ± 0.064	4.462LysVal: 4.462 ± 0.066	0.754LysTrp: 0.754 ± 0.025	2.187LysTyr: 2.187 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	7.722LeuAla: 7.722 ± 0.098	0.693LeuCys: 0.693 ± 0.026	4.504LeuAsp: 4.504 ± 0.069	6.525LeuGlu: 6.525 ± 0.079	4.795LeuPhe: 4.795 ± 0.084	6.045LeuGly: 6.045 ± 0.085	2.005LeuHis: 2.005 ± 0.042	7.239LeuIle: 7.239 ± 0.109	6.364LeuLys: 6.364 ± 0.077	9.875LeuLeu: 9.875 ± 0.129	2.593LeuMet: 2.593 ± 0.046	4.607LeuAsn: 4.607 ± 0.064	3.807LeuPro: 3.807 ± 0.066	3.957LeuGln: 3.957 ± 0.065	3.389LeuArg: 3.389 ± 0.062	6.14LeuSer: 6.14 ± 0.08	5.835LeuThr: 5.835 ± 0.076	6.349LeuVal: 6.349 ± 0.085	0.743LeuTrp: 0.743 ± 0.029	3.165LeuTyr: 3.165 ± 0.067	0.0LeuXaa: 0.0 ± 0.0
Met	2.066MetAla: 2.066 ± 0.044	0.14MetCys: 0.14 ± 0.012	1.515MetAsp: 1.515 ± 0.04	2.004MetGlu: 2.004 ± 0.043	1.124MetPhe: 1.124 ± 0.037	1.639MetGly: 1.639 ± 0.04	0.537MetHis: 0.537 ± 0.023	2.125MetIle: 2.125 ± 0.047	2.396MetLys: 2.396 ± 0.053	2.625MetLeu: 2.625 ± 0.048	0.906MetMet: 0.906 ± 0.03	1.627MetAsn: 1.627 ± 0.038	1.089MetPro: 1.089 ± 0.036	1.194MetGln: 1.194 ± 0.033	1.139MetArg: 1.139 ± 0.032	1.674MetSer: 1.674 ± 0.041	1.898MetThr: 1.898 ± 0.037	1.538MetVal: 1.538 ± 0.038	0.209MetTrp: 0.209 ± 0.014	0.856MetTyr: 0.856 ± 0.032	0.0MetXaa: 0.0 ± 0.0
Asn	3.23AsnAla: 3.23 ± 0.067	0.29AsnCys: 0.29 ± 0.017	2.331AsnAsp: 2.331 ± 0.048	4.011AsnGlu: 4.011 ± 0.07	1.919AsnPhe: 1.919 ± 0.039	3.389AsnGly: 3.389 ± 0.065	0.896AsnHis: 0.896 ± 0.026	3.735AsnIle: 3.735 ± 0.061	2.823AsnLys: 2.823 ± 0.053	3.98AsnLeu: 3.98 ± 0.061	1.291AsnMet: 1.291 ± 0.035	2.195AsnAsn: 2.195 ± 0.065	2.105AsnPro: 2.105 ± 0.044	1.547AsnGln: 1.547 ± 0.043	1.997AsnArg: 1.997 ± 0.046	2.543AsnSer: 2.543 ± 0.059	2.474AsnThr: 2.474 ± 0.051	3.106AsnVal: 3.106 ± 0.053	0.501AsnTrp: 0.501 ± 0.025	1.791AsnTyr: 1.791 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	2.443ProAla: 2.443 ± 0.05	0.185ProCys: 0.185 ± 0.013	1.767ProAsp: 1.767 ± 0.041	2.804ProGlu: 2.804 ± 0.056	1.991ProPhe: 1.991 ± 0.054	2.105ProGly: 2.105 ± 0.049	0.816ProHis: 0.816 ± 0.029	2.868ProIle: 2.868 ± 0.048	2.096ProLys: 2.096 ± 0.045	3.323ProLeu: 3.323 ± 0.056	0.874ProMet: 0.874 ± 0.036	1.703ProAsn: 1.703 ± 0.037	0.935ProPro: 0.935 ± 0.029	1.245ProGln: 1.245 ± 0.038	0.951ProArg: 0.951 ± 0.03	2.026ProSer: 2.026 ± 0.044	1.99ProThr: 1.99 ± 0.042	2.806ProVal: 2.806 ± 0.053	0.305ProTrp: 0.305 ± 0.016	1.368ProTyr: 1.368 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	2.858GlnAla: 2.858 ± 0.051	0.192GlnCys: 0.192 ± 0.012	1.571GlnAsp: 1.571 ± 0.035	2.615GlnGlu: 2.615 ± 0.047	1.947GlnPhe: 1.947 ± 0.048	2.086GlnGly: 2.086 ± 0.042	0.92GlnHis: 0.92 ± 0.032	2.971GlnIle: 2.971 ± 0.061	2.611GlnLys: 2.611 ± 0.051	4.704GlnLeu: 4.704 ± 0.069	1.252GlnMet: 1.252 ± 0.042	1.83GlnAsn: 1.83 ± 0.042	1.253GlnPro: 1.253 ± 0.041	2.519GlnGln: 2.519 ± 0.063	1.472GlnArg: 1.472 ± 0.039	2.205GlnSer: 2.205 ± 0.052	2.1GlnThr: 2.1 ± 0.046	2.477GlnVal: 2.477 ± 0.051	0.421GlnTrp: 0.421 ± 0.02	1.56GlnTyr: 1.56 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	2.644ArgAla: 2.644 ± 0.049	0.214ArgCys: 0.214 ± 0.017	1.929ArgAsp: 1.929 ± 0.044	3.051ArgGlu: 3.051 ± 0.059	1.842ArgPhe: 1.842 ± 0.043	2.252ArgGly: 2.252 ± 0.044	0.785ArgHis: 0.785 ± 0.03	3.024ArgIle: 3.024 ± 0.056	2.776ArgLys: 2.776 ± 0.053	3.683ArgLeu: 3.683 ± 0.06	1.165ArgMet: 1.165 ± 0.032	1.833ArgAsn: 1.833 ± 0.041	1.244ArgPro: 1.244 ± 0.029	1.564ArgGln: 1.564 ± 0.042	1.577ArgArg: 1.577 ± 0.046	2.014ArgSer: 2.014 ± 0.043	1.973ArgThr: 1.973 ± 0.042	2.466ArgVal: 2.466 ± 0.065	0.351ArgTrp: 0.351 ± 0.02	1.464ArgTyr: 1.464 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	3.914SerAla: 3.914 ± 0.066	0.349SerCys: 0.349 ± 0.021	2.696SerAsp: 2.696 ± 0.05	3.868SerGlu: 3.868 ± 0.06	3.117SerPhe: 3.117 ± 0.059	4.017SerGly: 4.017 ± 0.071	1.086SerHis: 1.086 ± 0.033	5.082SerIle: 5.082 ± 0.074	3.738SerLys: 3.738 ± 0.064	5.631SerLeu: 5.631 ± 0.085	1.648SerMet: 1.648 ± 0.037	2.644SerAsn: 2.644 ± 0.053	1.944SerPro: 1.944 ± 0.043	1.781SerGln: 1.781 ± 0.043	1.985SerArg: 1.985 ± 0.045	3.579SerSer: 3.579 ± 0.07	3.28SerThr: 3.28 ± 0.063	3.961SerVal: 3.961 ± 0.077	0.582SerTrp: 0.582 ± 0.024	2.281SerTyr: 2.281 ± 0.054	0.0SerXaa: 0.0 ± 0.0
Thr	4.456ThrAla: 4.456 ± 0.065	0.301ThrCys: 0.301 ± 0.017	2.895ThrAsp: 2.895 ± 0.056	3.981ThrGlu: 3.981 ± 0.066	2.822ThrPhe: 2.822 ± 0.057	4.065ThrGly: 4.065 ± 0.063	1.097ThrHis: 1.097 ± 0.032	4.967ThrIle: 4.967 ± 0.069	3.539ThrLys: 3.539 ± 0.056	5.366ThrLeu: 5.366 ± 0.071	1.442ThrMet: 1.442 ± 0.032	2.637ThrAsn: 2.637 ± 0.05	2.276ThrPro: 2.276 ± 0.046	1.57ThrGln: 1.57 ± 0.041	1.803ThrArg: 1.803 ± 0.042	3.334ThrSer: 3.334 ± 0.05	3.451ThrThr: 3.451 ± 0.066	4.534ThrVal: 4.534 ± 0.069	0.479ThrTrp: 0.479 ± 0.021	2.078ThrTyr: 2.078 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	5.552ValAla: 5.552 ± 0.078	0.536ValCys: 0.536 ± 0.02	3.59ValAsp: 3.59 ± 0.069	5.315ValGlu: 5.315 ± 0.078	3.086ValPhe: 3.086 ± 0.063	4.698ValGly: 4.698 ± 0.071	1.304ValHis: 1.304 ± 0.032	5.667ValIle: 5.667 ± 0.076	4.666ValLys: 4.666 ± 0.067	6.789ValLeu: 6.789 ± 0.084	1.949ValMet: 1.949 ± 0.043	3.105ValAsn: 3.105 ± 0.058	2.621ValPro: 2.621 ± 0.053	2.606ValGln: 2.606 ± 0.05	2.623ValArg: 2.623 ± 0.059	4.266ValSer: 4.266 ± 0.073	4.463ValThr: 4.463 ± 0.072	5.301ValVal: 5.301 ± 0.086	0.561ValTrp: 0.561 ± 0.026	2.192ValTyr: 2.192 ± 0.041	0.0ValXaa: 0.0 ± 0.0
Trp	0.585TrpAla: 0.585 ± 0.027	0.075TrpCys: 0.075 ± 0.008	0.497TrpAsp: 0.497 ± 0.024	0.581TrpGlu: 0.581 ± 0.024	0.475TrpPhe: 0.475 ± 0.022	0.621TrpGly: 0.621 ± 0.023	0.221TrpHis: 0.221 ± 0.014	0.776TrpIle: 0.776 ± 0.031	0.618TrpLys: 0.618 ± 0.024	1.05TrpLeu: 1.05 ± 0.034	0.317TrpMet: 0.317 ± 0.019	0.486TrpAsn: 0.486 ± 0.022	0.212TrpPro: 0.212 ± 0.015	0.41TrpGln: 0.41 ± 0.02	0.337TrpArg: 0.337 ± 0.017	0.53TrpSer: 0.53 ± 0.023	0.521TrpThr: 0.521 ± 0.025	0.583TrpVal: 0.583 ± 0.027	0.1TrpTrp: 0.1 ± 0.011	0.309TrpTyr: 0.309 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.425TyrAla: 2.425 ± 0.047	0.297TyrCys: 0.297 ± 0.017	1.999TyrAsp: 1.999 ± 0.047	2.905TyrGlu: 2.905 ± 0.064	1.912TyrPhe: 1.912 ± 0.049	2.355TyrGly: 2.355 ± 0.052	0.675TyrHis: 0.675 ± 0.023	2.788TyrIle: 2.788 ± 0.054	2.145TyrLys: 2.145 ± 0.049	3.526TyrLeu: 3.526 ± 0.064	0.916TyrMet: 0.916 ± 0.032	1.692TyrAsn: 1.692 ± 0.044	1.307TyrPro: 1.307 ± 0.036	1.098TyrGln: 1.098 ± 0.028	1.534TyrArg: 1.534 ± 0.043	2.206TyrSer: 2.206 ± 0.05	1.987TyrThr: 1.987 ± 0.044	2.284TyrVal: 2.284 ± 0.051	0.365TyrTrp: 0.365 ± 0.021	1.555TyrTyr: 1.555 ± 0.046	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3812 proteins (1086794 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---