Amino acid dipepetide frequency for Beihai sobemo-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.04AlaAla: 12.04 ± 2.375
0.669AlaCys: 0.669 ± 0.615
5.351AlaAsp: 5.351 ± 0.577
7.358AlaGlu: 7.358 ± 2.603
3.344AlaPhe: 3.344 ± 1.31
2.676AlaGly: 2.676 ± 0.289
2.007AlaHis: 2.007 ± 0.829
4.013AlaIle: 4.013 ± 0.696
4.682AlaLys: 4.682 ± 2.061
10.033AlaLeu: 10.033 ± 3.213
2.676AlaMet: 2.676 ± 0.738
3.344AlaAsn: 3.344 ± 0.774
2.676AlaPro: 2.676 ± 0.738
6.689AlaGln: 6.689 ± 0.837
5.351AlaArg: 5.351 ± 1.079
6.02AlaSer: 6.02 ± 2.848
1.338AlaThr: 1.338 ± 1.205
7.358AlaVal: 7.358 ± 2.157
2.007AlaTrp: 2.007 ± 0.198
0.669AlaTyr: 0.669 ± 0.486
0.0AlaXaa: 0.0 ± 0.0
Cys
1.338CysAla: 1.338 ± 1.229
0.0CysCys: 0.0 ± 0.0
2.007CysAsp: 2.007 ± 0.198
0.669CysGlu: 0.669 ± 0.486
1.338CysPhe: 1.338 ± 1.205
1.338CysGly: 1.338 ± 1.205
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.007CysLeu: 2.007 ± 1.019
0.0CysMet: 0.0 ± 0.0
0.669CysAsn: 0.669 ± 0.615
0.669CysPro: 0.669 ± 0.615
0.0CysGln: 0.0 ± 0.0
0.669CysArg: 0.669 ± 0.615
2.007CysSer: 2.007 ± 0.198
0.669CysThr: 0.669 ± 0.602
1.338CysVal: 1.338 ± 0.51
0.0CysTrp: 0.0 ± 0.0
0.669CysTyr: 0.669 ± 0.602
0.0CysXaa: 0.0 ± 0.0
Asp
3.344AspAla: 3.344 ± 1.344
0.669AspCys: 0.669 ± 0.615
5.351AspAsp: 5.351 ± 2.23
3.344AspGlu: 3.344 ± 1.654
4.013AspPhe: 4.013 ± 1.259
2.676AspGly: 2.676 ± 1.199
0.669AspHis: 0.669 ± 0.486
2.007AspIle: 2.007 ± 0.829
1.338AspLys: 1.338 ± 0.683
5.351AspLeu: 5.351 ± 1.476
0.669AspMet: 0.669 ± 0.602
1.338AspAsn: 1.338 ± 0.51
3.344AspPro: 3.344 ± 0.528
4.013AspGln: 4.013 ± 1.316
4.682AspArg: 4.682 ± 1.967
2.676AspSer: 2.676 ± 1.604
4.682AspThr: 4.682 ± 0.096
4.013AspVal: 4.013 ± 0.63
1.338AspTrp: 1.338 ± 0.51
3.344AspTyr: 3.344 ± 0.485
0.0AspXaa: 0.0 ± 0.0
Glu
7.358GluAla: 7.358 ± 1.27
1.338GluCys: 1.338 ± 0.683
4.013GluAsp: 4.013 ± 0.63
2.007GluGlu: 2.007 ± 0.829
4.013GluPhe: 4.013 ± 1.259
2.007GluGly: 2.007 ± 0.198
2.007GluHis: 2.007 ± 1.457
3.344GluIle: 3.344 ± 1.344
4.682GluLys: 4.682 ± 0.889
5.351GluLeu: 5.351 ± 1.52
2.676GluMet: 2.676 ± 1.075
2.007GluAsn: 2.007 ± 0.783
5.351GluPro: 5.351 ± 0.589
1.338GluGln: 1.338 ± 0.538
6.02GluArg: 6.02 ± 1.926
8.027GluSer: 8.027 ± 2.344
4.013GluThr: 4.013 ± 1.069
2.676GluVal: 2.676 ± 0.738
2.676GluTrp: 2.676 ± 1.604
2.007GluTyr: 2.007 ± 1.807
0.0GluXaa: 0.0 ± 0.0
Phe
1.338PheAla: 1.338 ± 1.205
2.007PheCys: 2.007 ± 0.198
2.676PheAsp: 2.676 ± 1.199
1.338PheGlu: 1.338 ± 0.51
1.338PhePhe: 1.338 ± 0.971
2.007PheGly: 2.007 ± 0.829
0.669PheHis: 0.669 ± 0.615
1.338PheIle: 1.338 ± 0.683
0.669PheLys: 0.669 ± 0.602
2.676PheLeu: 2.676 ± 0.738
0.669PheMet: 0.669 ± 0.602
1.338PheAsn: 1.338 ± 0.683
2.676PhePro: 2.676 ± 0.289
0.669PheGln: 0.669 ± 0.486
1.338PheArg: 1.338 ± 0.51
2.676PheSer: 2.676 ± 1.247
1.338PheThr: 1.338 ± 0.538
4.682PheVal: 4.682 ± 1.047
0.0PheTrp: 0.0 ± 0.0
1.338PheTyr: 1.338 ± 0.538
0.0PheXaa: 0.0 ± 0.0
Gly
10.033GlyAla: 10.033 ± 2.276
1.338GlyCys: 1.338 ± 0.683
4.682GlyAsp: 4.682 ± 1.711
4.682GlyGlu: 4.682 ± 0.096
3.344GlyPhe: 3.344 ± 1.49
5.351GlyGly: 5.351 ± 2.495
0.669GlyHis: 0.669 ± 0.615
2.007GlyIle: 2.007 ± 1.132
4.013GlyLys: 4.013 ± 1.259
2.007GlyLeu: 2.007 ± 0.198
0.669GlyMet: 0.669 ± 0.615
2.007GlyAsn: 2.007 ± 0.783
2.676GlyPro: 2.676 ± 1.604
3.344GlyGln: 3.344 ± 1.533
3.344GlyArg: 3.344 ± 1.654
8.696GlySer: 8.696 ± 2.78
2.676GlyThr: 2.676 ± 1.715
6.02GlyVal: 6.02 ± 1.062
0.669GlyTrp: 0.669 ± 0.615
0.669GlyTyr: 0.669 ± 0.486
0.0GlyXaa: 0.0 ± 0.0
His
0.669HisAla: 0.669 ± 0.486
1.338HisCys: 1.338 ± 0.538
1.338HisAsp: 1.338 ± 0.971
2.007HisGlu: 2.007 ± 0.829
0.0HisPhe: 0.0 ± 0.0
2.676HisGly: 2.676 ± 0.289
1.338HisHis: 1.338 ± 0.51
0.669HisIle: 0.669 ± 0.486
1.338HisLys: 1.338 ± 0.683
1.338HisLeu: 1.338 ± 0.971
0.669HisMet: 0.669 ± 0.615
0.0HisAsn: 0.0 ± 0.0
1.338HisPro: 1.338 ± 1.229
0.669HisGln: 0.669 ± 0.602
2.676HisArg: 2.676 ± 1.019
2.007HisSer: 2.007 ± 0.783
2.676HisThr: 2.676 ± 1.019
2.676HisVal: 2.676 ± 1.199
0.669HisTrp: 0.669 ± 0.615
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.013IleAla: 4.013 ± 0.696
0.669IleCys: 0.669 ± 0.486
2.007IleAsp: 2.007 ± 0.783
4.013IleGlu: 4.013 ± 1.566
1.338IlePhe: 1.338 ± 0.51
2.007IleGly: 2.007 ± 1.132
2.007IleHis: 2.007 ± 0.829
0.669IleIle: 0.669 ± 0.486
0.669IleLys: 0.669 ± 0.615
5.351IleLeu: 5.351 ± 0.589
0.669IleMet: 0.669 ± 0.615
1.338IleAsn: 1.338 ± 0.538
0.0IlePro: 0.0 ± 0.0
0.669IleGln: 0.669 ± 0.615
4.013IleArg: 4.013 ± 1.328
2.676IleSer: 2.676 ± 1.604
1.338IleThr: 1.338 ± 1.205
3.344IleVal: 3.344 ± 1.344
0.0IleTrp: 0.0 ± 0.0
0.669IleTyr: 0.669 ± 0.486
0.0IleXaa: 0.0 ± 0.0
Lys
4.682LysAla: 4.682 ± 2.061
0.669LysCys: 0.669 ± 0.486
2.676LysAsp: 2.676 ± 1.247
4.013LysGlu: 4.013 ± 2.122
1.338LysPhe: 1.338 ± 0.683
4.013LysGly: 4.013 ± 0.696
2.007LysHis: 2.007 ± 0.783
1.338LysIle: 1.338 ± 0.538
4.013LysLys: 4.013 ± 1.259
6.02LysLeu: 6.02 ± 2.079
0.0LysMet: 0.0 ± 0.0
2.007LysAsn: 2.007 ± 0.783
1.338LysPro: 1.338 ± 0.971
2.676LysGln: 2.676 ± 1.075
5.351LysArg: 5.351 ± 0.589
3.344LysSer: 3.344 ± 1.344
2.007LysThr: 2.007 ± 0.829
2.007LysVal: 2.007 ± 1.019
0.0LysTrp: 0.0 ± 0.0
2.676LysTyr: 2.676 ± 1.366
0.0LysXaa: 0.0 ± 0.0
Leu
4.013LeuAla: 4.013 ± 1.613
2.007LeuCys: 2.007 ± 1.844
4.682LeuAsp: 4.682 ± 1.98
6.02LeuGlu: 6.02 ± 1.188
2.007LeuPhe: 2.007 ± 0.198
8.027LeuGly: 8.027 ± 2.213
1.338LeuHis: 1.338 ± 0.51
4.013LeuIle: 4.013 ± 1.069
4.682LeuLys: 4.682 ± 2.596
7.358LeuLeu: 7.358 ± 1.277
3.344LeuMet: 3.344 ± 1.344
3.344LeuAsn: 3.344 ± 1.533
4.682LeuPro: 4.682 ± 1.015
2.676LeuGln: 2.676 ± 1.247
9.365LeuArg: 9.365 ± 0.795
6.689LeuSer: 6.689 ± 2.664
3.344LeuThr: 3.344 ± 0.528
4.682LeuVal: 4.682 ± 0.889
1.338LeuTrp: 1.338 ± 0.683
2.007LeuTyr: 2.007 ± 1.019
0.0LeuXaa: 0.0 ± 0.0
Met
2.676MetAla: 2.676 ± 1.199
0.669MetCys: 0.669 ± 0.602
1.338MetAsp: 1.338 ± 0.683
3.344MetGlu: 3.344 ± 1.31
0.0MetPhe: 0.0 ± 0.0
2.676MetGly: 2.676 ± 1.604
0.669MetHis: 0.669 ± 0.602
0.669MetIle: 0.669 ± 0.615
0.0MetLys: 0.0 ± 0.0
2.007MetLeu: 2.007 ± 0.198
0.0MetMet: 0.0 ± 0.0
2.007MetAsn: 2.007 ± 1.033
2.676MetPro: 2.676 ± 1.68
0.669MetGln: 0.669 ± 0.615
1.338MetArg: 1.338 ± 0.683
1.338MetSer: 1.338 ± 0.51
1.338MetThr: 1.338 ± 0.971
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.676AsnAla: 2.676 ± 0.289
0.0AsnCys: 0.0 ± 0.0
2.676AsnAsp: 2.676 ± 0.289
3.344AsnGlu: 3.344 ± 0.528
1.338AsnPhe: 1.338 ± 1.205
2.007AsnGly: 2.007 ± 0.829
0.669AsnHis: 0.669 ± 0.602
1.338AsnIle: 1.338 ± 1.229
2.007AsnLys: 2.007 ± 0.198
2.007AsnLeu: 2.007 ± 1.457
1.338AsnMet: 1.338 ± 1.205
1.338AsnAsn: 1.338 ± 0.683
2.007AsnPro: 2.007 ± 0.198
0.0AsnGln: 0.0 ± 0.0
2.676AsnArg: 2.676 ± 1.199
3.344AsnSer: 3.344 ± 0.528
1.338AsnThr: 1.338 ± 1.229
0.669AsnVal: 0.669 ± 0.602
1.338AsnTrp: 1.338 ± 0.538
0.669AsnTyr: 0.669 ± 0.615
0.0AsnXaa: 0.0 ± 0.0
Pro
7.358ProAla: 7.358 ± 2.576
0.0ProCys: 0.0 ± 0.0
1.338ProAsp: 1.338 ± 0.51
4.682ProGlu: 4.682 ± 0.975
2.676ProPhe: 2.676 ± 1.604
5.351ProGly: 5.351 ± 1.109
2.007ProHis: 2.007 ± 1.844
0.669ProIle: 0.669 ± 0.486
2.007ProLys: 2.007 ± 1.033
4.682ProLeu: 4.682 ± 1.687
1.338ProMet: 1.338 ± 0.51
0.669ProAsn: 0.669 ± 0.486
2.007ProPro: 2.007 ± 0.783
2.007ProGln: 2.007 ± 0.198
4.013ProArg: 4.013 ± 1.095
6.02ProSer: 6.02 ± 0.509
1.338ProThr: 1.338 ± 1.229
4.682ProVal: 4.682 ± 0.897
0.0ProTrp: 0.0 ± 0.0
1.338ProTyr: 1.338 ± 0.538
0.0ProXaa: 0.0 ± 0.0
Gln
2.676GlnAla: 2.676 ± 1.715
0.0GlnCys: 0.0 ± 0.0
2.676GlnAsp: 2.676 ± 0.738
4.682GlnGlu: 4.682 ± 1.047
0.669GlnPhe: 0.669 ± 0.602
2.007GlnGly: 2.007 ± 1.019
0.669GlnHis: 0.669 ± 0.486
2.676GlnIle: 2.676 ± 1.199
2.007GlnLys: 2.007 ± 1.132
2.007GlnLeu: 2.007 ± 1.033
1.338GlnMet: 1.338 ± 0.708
0.669GlnAsn: 0.669 ± 0.615
2.007GlnPro: 2.007 ± 1.033
2.676GlnGln: 2.676 ± 1.68
4.013GlnArg: 4.013 ± 1.259
2.007GlnSer: 2.007 ± 0.829
0.669GlnThr: 0.669 ± 0.486
4.013GlnVal: 4.013 ± 1.316
0.669GlnTrp: 0.669 ± 0.615
1.338GlnTyr: 1.338 ± 0.971
0.0GlnXaa: 0.0 ± 0.0
Arg
12.04ArgAla: 12.04 ± 1.345
0.669ArgCys: 0.669 ± 0.615
4.682ArgAsp: 4.682 ± 0.889
8.027ArgGlu: 8.027 ± 1.798
2.007ArgPhe: 2.007 ± 1.457
3.344ArgGly: 3.344 ± 0.485
2.007ArgHis: 2.007 ± 1.019
2.676ArgIle: 2.676 ± 1.604
4.013ArgLys: 4.013 ± 2.17
6.02ArgLeu: 6.02 ± 0.509
1.338ArgMet: 1.338 ± 0.971
1.338ArgAsn: 1.338 ± 0.683
4.013ArgPro: 4.013 ± 1.328
3.344ArgGln: 3.344 ± 0.485
12.709ArgArg: 12.709 ± 3.406
2.676ArgSer: 2.676 ± 0.289
2.676ArgThr: 2.676 ± 0.289
3.344ArgVal: 3.344 ± 0.485
0.669ArgTrp: 0.669 ± 0.615
2.676ArgTyr: 2.676 ± 1.019
0.0ArgXaa: 0.0 ± 0.0
Ser
2.007SerAla: 2.007 ± 1.033
0.669SerCys: 0.669 ± 0.486
2.007SerAsp: 2.007 ± 0.198
4.682SerGlu: 4.682 ± 1.078
0.669SerPhe: 0.669 ± 0.602
10.033SerGly: 10.033 ± 1.438
1.338SerHis: 1.338 ± 1.229
1.338SerIle: 1.338 ± 0.683
6.689SerLys: 6.689 ± 2.454
10.033SerLeu: 10.033 ± 3.337
2.007SerMet: 2.007 ± 1.457
4.013SerAsn: 4.013 ± 1.095
6.02SerPro: 6.02 ± 1.062
2.676SerGln: 2.676 ± 0.289
3.344SerArg: 3.344 ± 1.49
6.689SerSer: 6.689 ± 1.548
7.358SerThr: 7.358 ± 1.611
4.013SerVal: 4.013 ± 1.955
1.338SerTrp: 1.338 ± 1.205
2.007SerTyr: 2.007 ± 0.198
0.0SerXaa: 0.0 ± 0.0
Thr
4.013ThrAla: 4.013 ± 1.613
0.669ThrCys: 0.669 ± 0.602
3.344ThrAsp: 3.344 ± 1.791
2.007ThrGlu: 2.007 ± 0.198
2.676ThrPhe: 2.676 ± 1.604
4.682ThrGly: 4.682 ± 1.078
1.338ThrHis: 1.338 ± 0.971
3.344ThrIle: 3.344 ± 1.31
2.007ThrLys: 2.007 ± 1.019
1.338ThrLeu: 1.338 ± 0.971
0.669ThrMet: 0.669 ± 0.615
1.338ThrAsn: 1.338 ± 0.683
2.676ThrPro: 2.676 ± 1.366
1.338ThrGln: 1.338 ± 0.51
4.682ThrArg: 4.682 ± 0.096
2.676ThrSer: 2.676 ± 1.68
2.007ThrThr: 2.007 ± 0.198
1.338ThrVal: 1.338 ± 0.51
0.669ThrTrp: 0.669 ± 0.602
2.007ThrTyr: 2.007 ± 0.829
0.0ThrXaa: 0.0 ± 0.0
Val
5.351ValAla: 5.351 ± 0.589
0.669ValCys: 0.669 ± 0.602
4.013ValAsp: 4.013 ± 0.396
3.344ValGlu: 3.344 ± 1.791
0.0ValPhe: 0.0 ± 0.0
3.344ValGly: 3.344 ± 1.77
2.007ValHis: 2.007 ± 1.457
4.013ValIle: 4.013 ± 1.529
5.351ValLys: 5.351 ± 2.502
7.358ValLeu: 7.358 ± 1.277
1.338ValMet: 1.338 ± 0.683
2.007ValAsn: 2.007 ± 1.132
4.682ValPro: 4.682 ± 0.889
2.676ValGln: 2.676 ± 0.289
2.676ValArg: 2.676 ± 1.019
6.02ValSer: 6.02 ± 2.478
2.676ValThr: 2.676 ± 0.289
4.013ValVal: 4.013 ± 0.396
0.669ValTrp: 0.669 ± 0.602
2.007ValTyr: 2.007 ± 1.457
0.0ValXaa: 0.0 ± 0.0
Trp
0.669TrpAla: 0.669 ± 0.615
1.338TrpCys: 1.338 ± 0.683
1.338TrpAsp: 1.338 ± 0.51
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.669TrpHis: 0.669 ± 0.615
0.0TrpIle: 0.0 ± 0.0
0.669TrpLys: 0.669 ± 0.486
0.669TrpLeu: 0.669 ± 0.602
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
2.007TrpPro: 2.007 ± 0.198
1.338TrpGln: 1.338 ± 0.683
0.669TrpArg: 0.669 ± 0.615
2.676TrpSer: 2.676 ± 0.738
0.0TrpThr: 0.0 ± 0.0
1.338TrpVal: 1.338 ± 0.683
0.0TrpTrp: 0.0 ± 0.0
0.669TrpTyr: 0.669 ± 0.615
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.007TyrAla: 2.007 ± 0.783
0.0TyrCys: 0.0 ± 0.0
0.669TyrAsp: 0.669 ± 0.486
3.344TyrGlu: 3.344 ± 0.485
0.669TyrPhe: 0.669 ± 0.602
2.676TyrGly: 2.676 ± 1.199
2.007TyrHis: 2.007 ± 0.829
1.338TyrIle: 1.338 ± 1.205
1.338TyrLys: 1.338 ± 0.683
2.007TyrLeu: 2.007 ± 0.783
1.338TyrMet: 1.338 ± 1.039
2.007TyrAsn: 2.007 ± 0.829
1.338TyrPro: 1.338 ± 0.51
0.669TyrGln: 0.669 ± 0.615
1.338TyrArg: 1.338 ± 0.971
0.669TyrSer: 0.669 ± 0.615
1.338TyrThr: 1.338 ± 0.538
2.007TyrVal: 2.007 ± 1.151
0.0TyrTrp: 0.0 ± 0.0
0.669TyrTyr: 0.669 ± 0.486
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1496 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski