Human papillomavirus 52

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 9

Average proteome isoelectric point is 6.19

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q05138|VL1_HPV52 Major capsid protein L1 OS=Human papillomavirus 52 OX=10618 GN=L1 PE=1 SV=2
MM1 pKa = 7.76RR2 pKa = 11.84GDD4 pKa = 3.16KK5 pKa = 10.09ATIKK9 pKa = 10.64DD10 pKa = 4.45YY11 pKa = 11.08ILDD14 pKa = 4.17LQPEE18 pKa = 4.63TTDD21 pKa = 3.02LHH23 pKa = 8.19CYY25 pKa = 7.95EE26 pKa = 4.33QLGDD30 pKa = 4.07SSDD33 pKa = 4.14EE34 pKa = 4.08EE35 pKa = 4.41DD36 pKa = 3.31TDD38 pKa = 4.83GVDD41 pKa = 4.27RR42 pKa = 11.84PDD44 pKa = 3.65GQAEE48 pKa = 4.09QATSNYY54 pKa = 10.31YY55 pKa = 9.87IVTYY59 pKa = 10.07CHH61 pKa = 6.64SCDD64 pKa = 3.23STLRR68 pKa = 11.84LCIHH72 pKa = 6.2STATDD77 pKa = 3.66LRR79 pKa = 11.84TLQQMLLGTLQVVCPGCARR98 pKa = 11.84LL99 pKa = 3.78

Molecular weight: 11.03 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P36831|VE7_HPV52 Protein E7 OS=Human papillomavirus 52 OX=10618 GN=E7 PE=3 SV=1
MM1 pKa = 7.46FEE3 pKa = 5.09DD4 pKa = 4.11PATRR8 pKa = 11.84PRR10 pKa = 11.84TLHH13 pKa = 5.78EE14 pKa = 4.21LCEE17 pKa = 4.06VLEE20 pKa = 4.33EE21 pKa = 4.4SVHH24 pKa = 6.49EE25 pKa = 4.17IRR27 pKa = 11.84LQCVQCKK34 pKa = 10.1KK35 pKa = 9.38EE36 pKa = 3.84LQRR39 pKa = 11.84RR40 pKa = 11.84EE41 pKa = 3.85VYY43 pKa = 10.46KK44 pKa = 10.78FLFTDD49 pKa = 3.54LRR51 pKa = 11.84IVYY54 pKa = 9.76RR55 pKa = 11.84DD56 pKa = 3.44NNPYY60 pKa = 9.7GVCIMCLRR68 pKa = 11.84FLSKK72 pKa = 9.85ISEE75 pKa = 4.11YY76 pKa = 10.7RR77 pKa = 11.84HH78 pKa = 5.13YY79 pKa = 10.8QYY81 pKa = 11.73SLYY84 pKa = 10.91GKK86 pKa = 7.28TLEE89 pKa = 4.25EE90 pKa = 3.93RR91 pKa = 11.84VKK93 pKa = 10.95KK94 pKa = 9.52PLSEE98 pKa = 3.63ITIRR102 pKa = 11.84CIICQTPLCPEE113 pKa = 3.76EE114 pKa = 4.73KK115 pKa = 9.77EE116 pKa = 4.04RR117 pKa = 11.84HH118 pKa = 4.84VNANKK123 pKa = 10.15RR124 pKa = 11.84FHH126 pKa = 7.09NIMGRR131 pKa = 11.84WTGRR135 pKa = 11.84CSEE138 pKa = 4.38CWRR141 pKa = 11.84PRR143 pKa = 11.84PVTQVV148 pKa = 2.61

Molecular weight: 17.9 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2257

99

647

376.2

42.28

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.918 ± 0.485

2.836 ± 0.744

5.804 ± 0.757

5.494 ± 0.839

4.032 ± 0.83

6.026 ± 0.589

2.348 ± 0.298

5.848 ± 0.607

5.405 ± 0.893

7.532 ± 0.535

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.817 ± 0.2

4.475 ± 0.667

5.981 ± 1.274

4.608 ± 0.446

4.918 ± 0.734

7.975 ± 0.92

8.152 ± 1.12

6.557 ± 0.433

1.329 ± 0.348

3.943 ± 0.37
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski