Amino acid dipepetide frequency for Sediminihabitans luteus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	22.672AlaAla: 22.672 ± 0.244	0.89AlaCys: 0.89 ± 0.034	9.664AlaAsp: 9.664 ± 0.117	7.809AlaGlu: 7.809 ± 0.117	3.498AlaPhe: 3.498 ± 0.061	14.032AlaGly: 14.032 ± 0.134	2.957AlaHis: 2.957 ± 0.06	4.115AlaIle: 4.115 ± 0.08	2.111AlaLys: 2.111 ± 0.061	14.815AlaLeu: 14.815 ± 0.166	2.497AlaMet: 2.497 ± 0.06	1.848AlaAsn: 1.848 ± 0.044	8.415AlaPro: 8.415 ± 0.125	3.967AlaGln: 3.967 ± 0.065	11.41AlaArg: 11.41 ± 0.17	7.287AlaSer: 7.287 ± 0.087	9.27AlaThr: 9.27 ± 0.11	13.556AlaVal: 13.556 ± 0.149	2.263AlaTrp: 2.263 ± 0.052	2.428AlaTyr: 2.428 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.764CysAla: 0.764 ± 0.027	0.058CysCys: 0.058 ± 0.008	0.417CysAsp: 0.417 ± 0.024	0.28CysGlu: 0.28 ± 0.017	0.146CysPhe: 0.146 ± 0.012	0.641CysGly: 0.641 ± 0.027	0.111CysHis: 0.111 ± 0.01	0.137CysIle: 0.137 ± 0.01	0.059CysLys: 0.059 ± 0.007	0.439CysLeu: 0.439 ± 0.018	0.083CysMet: 0.083 ± 0.009	0.081CysAsn: 0.081 ± 0.01	0.352CysPro: 0.352 ± 0.023	0.111CysGln: 0.111 ± 0.01	0.338CysArg: 0.338 ± 0.019	0.36CysSer: 0.36 ± 0.021	0.486CysThr: 0.486 ± 0.039	0.621CysVal: 0.621 ± 0.025	0.089CysTrp: 0.089 ± 0.008	0.091CysTyr: 0.091 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	11.251AspAla: 11.251 ± 0.153	0.257AspCys: 0.257 ± 0.018	6.113AspAsp: 6.113 ± 0.164	4.412AspGlu: 4.412 ± 0.081	1.301AspPhe: 1.301 ± 0.037	7.691AspGly: 7.691 ± 0.132	1.372AspHis: 1.372 ± 0.042	1.22AspIle: 1.22 ± 0.038	0.852AspLys: 0.852 ± 0.036	7.145AspLeu: 7.145 ± 0.096	0.738AspMet: 0.738 ± 0.028	0.759AspAsn: 0.759 ± 0.03	5.029AspPro: 5.029 ± 0.117	1.537AspGln: 1.537 ± 0.044	4.368AspArg: 4.368 ± 0.072	2.119AspSer: 2.119 ± 0.049	2.9AspThr: 2.9 ± 0.058	8.106AspVal: 8.106 ± 0.114	0.846AspTrp: 0.846 ± 0.03	1.075AspTyr: 1.075 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	6.785GluAla: 6.785 ± 0.097	0.242GluCys: 0.242 ± 0.017	2.763GluAsp: 2.763 ± 0.054	2.242GluGlu: 2.242 ± 0.052	1.282GluPhe: 1.282 ± 0.041	3.982GluGly: 3.982 ± 0.071	1.739GluHis: 1.739 ± 0.044	2.343GluIle: 2.343 ± 0.058	1.095GluLys: 1.095 ± 0.042	5.796GluLeu: 5.796 ± 0.096	0.778GluMet: 0.778 ± 0.03	1.042GluAsn: 1.042 ± 0.036	3.239GluPro: 3.239 ± 0.072	1.993GluGln: 1.993 ± 0.056	4.982GluArg: 4.982 ± 0.085	2.589GluSer: 2.589 ± 0.054	2.877GluThr: 2.877 ± 0.059	5.277GluVal: 5.277 ± 0.081	0.6GluTrp: 0.6 ± 0.026	0.93GluTyr: 0.93 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	3.582PheAla: 3.582 ± 0.065	0.179PheCys: 0.179 ± 0.014	2.015PheAsp: 2.015 ± 0.052	1.422PheGlu: 1.422 ± 0.044	0.76PhePhe: 0.76 ± 0.034	2.74PheGly: 2.74 ± 0.058	0.463PheHis: 0.463 ± 0.023	0.528PheIle: 0.528 ± 0.024	0.321PheLys: 0.321 ± 0.021	2.129PheLeu: 2.129 ± 0.058	0.33PheMet: 0.33 ± 0.02	0.45PheAsn: 0.45 ± 0.022	1.124PhePro: 1.124 ± 0.034	0.544PheGln: 0.544 ± 0.019	1.501PheArg: 1.501 ± 0.041	1.349PheSer: 1.349 ± 0.041	1.799PheThr: 1.799 ± 0.057	2.772PheVal: 2.772 ± 0.062	0.431PheTrp: 0.431 ± 0.026	0.514PheTyr: 0.514 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	12.799GlyAla: 12.799 ± 0.143	0.6GlyCys: 0.6 ± 0.031	5.791GlyAsp: 5.791 ± 0.111	4.726GlyGlu: 4.726 ± 0.081	2.776GlyPhe: 2.776 ± 0.066	8.325GlyGly: 8.325 ± 0.117	1.94GlyHis: 1.94 ± 0.046	3.256GlyIle: 3.256 ± 0.065	1.795GlyLys: 1.795 ± 0.051	9.033GlyLeu: 9.033 ± 0.129	1.773GlyMet: 1.773 ± 0.047	1.389GlyAsn: 1.389 ± 0.039	5.305GlyPro: 5.305 ± 0.094	2.304GlyGln: 2.304 ± 0.055	6.89GlyArg: 6.89 ± 0.097	5.477GlySer: 5.477 ± 0.077	7.615GlyThr: 7.615 ± 0.122	9.09GlyVal: 9.09 ± 0.107	1.695GlyTrp: 1.695 ± 0.04	2.094GlyTyr: 2.094 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.921HisAla: 2.921 ± 0.057	0.108HisCys: 0.108 ± 0.011	1.651HisAsp: 1.651 ± 0.048	1.26HisGlu: 1.26 ± 0.035	0.41HisPhe: 0.41 ± 0.021	2.309HisGly: 2.309 ± 0.054	0.542HisHis: 0.542 ± 0.024	0.342HisIle: 0.342 ± 0.018	0.235HisLys: 0.235 ± 0.015	2.23HisLeu: 2.23 ± 0.057	0.232HisMet: 0.232 ± 0.015	0.289HisAsn: 0.289 ± 0.017	1.506HisPro: 1.506 ± 0.041	0.5HisGln: 0.5 ± 0.021	1.741HisArg: 1.741 ± 0.043	0.701HisSer: 0.701 ± 0.023	0.997HisThr: 0.997 ± 0.033	2.204HisVal: 2.204 ± 0.049	0.275HisTrp: 0.275 ± 0.017	0.353HisTyr: 0.353 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	4.342IleAla: 4.342 ± 0.084	0.178IleCys: 0.178 ± 0.013	2.411IleAsp: 2.411 ± 0.05	1.811IleGlu: 1.811 ± 0.048	0.748IlePhe: 0.748 ± 0.031	3.029IleGly: 3.029 ± 0.067	0.474IleHis: 0.474 ± 0.024	0.814IleIle: 0.814 ± 0.038	0.57IleLys: 0.57 ± 0.032	2.37IleLeu: 2.37 ± 0.062	0.397IleMet: 0.397 ± 0.022	0.558IleAsn: 0.558 ± 0.025	1.512IlePro: 1.512 ± 0.046	0.561IleGln: 0.561 ± 0.025	1.558IleArg: 1.558 ± 0.046	1.497IleSer: 1.497 ± 0.043	2.079IleThr: 2.079 ± 0.059	3.139IleVal: 3.139 ± 0.068	0.3IleTrp: 0.3 ± 0.018	0.447IleTyr: 0.447 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	2.071LysAla: 2.071 ± 0.069	0.067LysCys: 0.067 ± 0.008	1.067LysAsp: 1.067 ± 0.037	0.719LysGlu: 0.719 ± 0.03	0.375LysPhe: 0.375 ± 0.02	1.338LysGly: 1.338 ± 0.046	0.372LysHis: 0.372 ± 0.022	0.696LysIle: 0.696 ± 0.028	0.527LysLys: 0.527 ± 0.032	1.173LysLeu: 1.173 ± 0.041	0.249LysMet: 0.249 ± 0.016	0.385LysAsn: 0.385 ± 0.02	0.867LysPro: 0.867 ± 0.039	0.454LysGln: 0.454 ± 0.025	0.987LysArg: 0.987 ± 0.042	0.869LysSer: 0.869 ± 0.033	0.904LysThr: 0.904 ± 0.033	1.588LysVal: 1.588 ± 0.054	0.145LysTrp: 0.145 ± 0.013	0.343LysTyr: 0.343 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	16.27LeuAla: 16.27 ± 0.18	0.571LeuCys: 0.571 ± 0.026	7.717LeuAsp: 7.717 ± 0.103	4.824LeuGlu: 4.824 ± 0.072	2.105LeuPhe: 2.105 ± 0.057	9.718LeuGly: 9.718 ± 0.115	1.944LeuHis: 1.944 ± 0.047	2.037LeuIle: 2.037 ± 0.063	1.182LeuLys: 1.182 ± 0.042	9.667LeuLeu: 9.667 ± 0.135	1.294LeuMet: 1.294 ± 0.034	1.262LeuAsn: 1.262 ± 0.045	5.466LeuPro: 5.466 ± 0.079	1.91LeuGln: 1.91 ± 0.049	7.448LeuArg: 7.448 ± 0.102	4.234LeuSer: 4.234 ± 0.071	6.233LeuThr: 6.233 ± 0.088	11.675LeuVal: 11.675 ± 0.148	1.239LeuTrp: 1.239 ± 0.04	1.404LeuTyr: 1.404 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	1.778MetAla: 1.778 ± 0.046	0.083MetCys: 0.083 ± 0.01	0.766MetAsp: 0.766 ± 0.026	0.558MetGlu: 0.558 ± 0.027	0.424MetPhe: 0.424 ± 0.019	1.095MetGly: 1.095 ± 0.044	0.328MetHis: 0.328 ± 0.019	0.618MetIle: 0.618 ± 0.025	0.271MetLys: 0.271 ± 0.017	1.665MetLeu: 1.665 ± 0.042	0.22MetMet: 0.22 ± 0.015	0.343MetAsn: 0.343 ± 0.019	0.974MetPro: 0.974 ± 0.032	0.386MetGln: 0.386 ± 0.021	1.231MetArg: 1.231 ± 0.032	1.368MetSer: 1.368 ± 0.035	1.671MetThr: 1.671 ± 0.042	1.214MetVal: 1.214 ± 0.034	0.15MetTrp: 0.15 ± 0.011	0.231MetTyr: 0.231 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	1.848AsnAla: 1.848 ± 0.042	0.099AsnCys: 0.099 ± 0.018	0.952AsnAsp: 0.952 ± 0.033	0.712AsnGlu: 0.712 ± 0.028	0.431AsnPhe: 0.431 ± 0.019	1.471AsnGly: 1.471 ± 0.049	0.357AsnHis: 0.357 ± 0.019	0.477AsnIle: 0.477 ± 0.025	0.309AsnLys: 0.309 ± 0.02	1.551AsnLeu: 1.551 ± 0.045	0.218AsnMet: 0.218 ± 0.015	0.305AsnAsn: 0.305 ± 0.014	1.233AsnPro: 1.233 ± 0.035	0.431AsnGln: 0.431 ± 0.023	0.894AsnArg: 0.894 ± 0.03	0.655AsnSer: 0.655 ± 0.028	0.865AsnThr: 0.865 ± 0.054	1.504AsnVal: 1.504 ± 0.038	0.191AsnTrp: 0.191 ± 0.013	0.372AsnTyr: 0.372 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	9.272ProAla: 9.272 ± 0.132	0.24ProCys: 0.24 ± 0.016	4.716ProAsp: 4.716 ± 0.078	3.808ProGlu: 3.808 ± 0.075	1.404ProPhe: 1.404 ± 0.038	6.523ProGly: 6.523 ± 0.116	1.181ProHis: 1.181 ± 0.037	1.312ProIle: 1.312 ± 0.036	0.718ProLys: 0.718 ± 0.035	4.719ProLeu: 4.719 ± 0.065	0.799ProMet: 0.799 ± 0.032	0.737ProAsn: 0.737 ± 0.029	2.903ProPro: 2.903 ± 0.072	1.466ProGln: 1.466 ± 0.041	4.02ProArg: 4.02 ± 0.079	3.342ProSer: 3.342 ± 0.061	4.36ProThr: 4.36 ± 0.084	5.888ProVal: 5.888 ± 0.092	0.988ProTrp: 0.988 ± 0.032	1.036ProTyr: 1.036 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.198GlnAla: 3.198 ± 0.065	0.131GlnCys: 0.131 ± 0.012	1.588GlnAsp: 1.588 ± 0.041	1.139GlnGlu: 1.139 ± 0.036	0.592GlnPhe: 0.592 ± 0.02	2.262GlnGly: 2.262 ± 0.055	0.663GlnHis: 0.663 ± 0.026	1.017GlnIle: 1.017 ± 0.03	0.413GlnLys: 0.413 ± 0.021	2.3GlnLeu: 2.3 ± 0.053	0.441GlnMet: 0.441 ± 0.021	0.476GlnAsn: 0.476 ± 0.022	1.287GlnPro: 1.287 ± 0.047	0.916GlnGln: 0.916 ± 0.036	2.071GlnArg: 2.071 ± 0.054	1.086GlnSer: 1.086 ± 0.036	1.269GlnThr: 1.269 ± 0.034	2.878GlnVal: 2.878 ± 0.053	0.387GlnTrp: 0.387 ± 0.021	0.521GlnTyr: 0.521 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	10.634ArgAla: 10.634 ± 0.159	0.434ArgCys: 0.434 ± 0.024	4.449ArgAsp: 4.449 ± 0.076	4.179ArgGlu: 4.179 ± 0.075	1.968ArgPhe: 1.968 ± 0.047	5.827ArgGly: 5.827 ± 0.095	1.585ArgHis: 1.585 ± 0.04	2.379ArgIle: 2.379 ± 0.052	1.105ArgLys: 1.105 ± 0.037	7.3ArgLeu: 7.3 ± 0.1	1.503ArgMet: 1.503 ± 0.034	0.996ArgAsn: 0.996 ± 0.036	4.34ArgPro: 4.34 ± 0.071	1.603ArgGln: 1.603 ± 0.039	7.408ArgArg: 7.408 ± 0.122	4.034ArgSer: 4.034 ± 0.076	5.564ArgThr: 5.564 ± 0.079	6.684ArgVal: 6.684 ± 0.097	1.436ArgTrp: 1.436 ± 0.039	1.503ArgTyr: 1.503 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.093SerAla: 7.093 ± 0.094	0.297SerCys: 0.297 ± 0.018	3.237SerAsp: 3.237 ± 0.066	2.11SerGlu: 2.11 ± 0.043	1.499SerPhe: 1.499 ± 0.04	5.353SerGly: 5.353 ± 0.07	0.884SerHis: 0.884 ± 0.03	1.696SerIle: 1.696 ± 0.049	0.77SerLys: 0.77 ± 0.028	4.585SerLeu: 4.585 ± 0.064	1.005SerMet: 1.005 ± 0.03	0.845SerAsn: 0.845 ± 0.029	3.032SerPro: 3.032 ± 0.061	1.186SerGln: 1.186 ± 0.038	3.513SerArg: 3.513 ± 0.07	3.237SerSer: 3.237 ± 0.076	4.239SerThr: 4.239 ± 0.088	4.463SerVal: 4.463 ± 0.085	0.871SerTrp: 0.871 ± 0.029	1.0SerTyr: 1.0 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	9.022ThrAla: 9.022 ± 0.113	0.401ThrCys: 0.401 ± 0.03	4.251ThrAsp: 4.251 ± 0.077	2.933ThrGlu: 2.933 ± 0.067	2.025ThrPhe: 2.025 ± 0.053	6.753ThrGly: 6.753 ± 0.13	1.221ThrHis: 1.221 ± 0.034	2.224ThrIle: 2.224 ± 0.064	0.989ThrLys: 0.989 ± 0.039	6.311ThrLeu: 6.311 ± 0.082	0.946ThrMet: 0.946 ± 0.033	1.07ThrAsn: 1.07 ± 0.057	5.004ThrPro: 5.004 ± 0.092	1.535ThrGln: 1.535 ± 0.043	3.976ThrArg: 3.976 ± 0.07	4.204ThrSer: 4.204 ± 0.067	5.247ThrThr: 5.247 ± 0.109	6.931ThrVal: 6.931 ± 0.168	1.086ThrTrp: 1.086 ± 0.042	1.43ThrTyr: 1.43 ± 0.076	0.0ThrXaa: 0.0 ± 0.0
Val	15.015ValAla: 15.015 ± 0.14	0.592ValCys: 0.592 ± 0.025	7.29ValAsp: 7.29 ± 0.117	6.003ValGlu: 6.003 ± 0.078	2.148ValPhe: 2.148 ± 0.053	8.58ValGly: 8.58 ± 0.111	2.065ValHis: 2.065 ± 0.045	2.72ValIle: 2.72 ± 0.06	1.337ValLys: 1.337 ± 0.04	11.446ValLeu: 11.446 ± 0.134	1.424ValMet: 1.424 ± 0.04	1.438ValAsn: 1.438 ± 0.035	6.182ValPro: 6.182 ± 0.089	2.276ValGln: 2.276 ± 0.05	7.969ValArg: 7.969 ± 0.108	4.595ValSer: 4.595 ± 0.071	6.915ValThr: 6.915 ± 0.177	13.103ValVal: 13.103 ± 0.161	1.287ValTrp: 1.287 ± 0.04	1.496ValTyr: 1.496 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.782TrpAla: 1.782 ± 0.046	0.115TrpCys: 0.115 ± 0.01	0.954TrpAsp: 0.954 ± 0.029	0.638TrpGlu: 0.638 ± 0.029	0.529TrpPhe: 0.529 ± 0.024	1.11TrpGly: 1.11 ± 0.04	0.332TrpHis: 0.332 ± 0.019	0.545TrpIle: 0.545 ± 0.023	0.25TrpLys: 0.25 ± 0.016	1.598TrpLeu: 1.598 ± 0.044	0.243TrpMet: 0.243 ± 0.015	0.331TrpAsn: 0.331 ± 0.02	0.712TrpPro: 0.712 ± 0.026	0.462TrpGln: 0.462 ± 0.02	1.22TrpArg: 1.22 ± 0.046	1.043TrpSer: 1.043 ± 0.037	1.115TrpThr: 1.115 ± 0.044	1.304TrpVal: 1.304 ± 0.041	0.413TrpTrp: 0.413 ± 0.022	0.291TrpTyr: 0.291 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.404TyrAla: 2.404 ± 0.049	0.118TyrCys: 0.118 ± 0.011	1.281TyrAsp: 1.281 ± 0.037	0.99TyrGlu: 0.99 ± 0.031	0.531TyrPhe: 0.531 ± 0.023	1.893TyrGly: 1.893 ± 0.052	0.276TyrHis: 0.276 ± 0.016	0.32TyrIle: 0.32 ± 0.019	0.287TyrLys: 0.287 ± 0.02	1.932TyrLeu: 1.932 ± 0.042	0.203TyrMet: 0.203 ± 0.016	0.27TyrAsn: 0.27 ± 0.016	0.947TyrPro: 0.947 ± 0.035	0.493TyrGln: 0.493 ± 0.026	1.41TyrArg: 1.41 ± 0.039	0.872TyrSer: 0.872 ± 0.03	1.155TyrThr: 1.155 ± 0.078	1.883TyrVal: 1.883 ± 0.046	0.294TyrTrp: 0.294 ± 0.017	0.395TyrTyr: 0.395 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2995 proteins (1036919 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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