Amino acid dipepetide frequency for Bettongia penicillata papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.829AlaAla: 2.829 ± 1.51
0.404AlaCys: 0.404 ± 0.325
2.829AlaAsp: 2.829 ± 0.893
2.021AlaGlu: 2.021 ± 0.816
2.021AlaPhe: 2.021 ± 0.701
2.829AlaGly: 2.829 ± 0.539
1.213AlaHis: 1.213 ± 0.361
2.829AlaIle: 2.829 ± 1.031
2.425AlaLys: 2.425 ± 1.313
2.425AlaLeu: 2.425 ± 0.7
0.808AlaMet: 0.808 ± 0.649
1.213AlaAsn: 1.213 ± 0.545
5.255AlaPro: 5.255 ± 1.976
3.638AlaGln: 3.638 ± 1.247
2.021AlaArg: 2.021 ± 0.409
2.829AlaSer: 2.829 ± 1.033
2.425AlaThr: 2.425 ± 0.632
3.234AlaVal: 3.234 ± 0.849
0.808AlaTrp: 0.808 ± 0.372
0.808AlaTyr: 0.808 ± 0.656
0.0AlaXaa: 0.0 ± 0.0
Cys
1.617CysAla: 1.617 ± 0.671
2.021CysCys: 2.021 ± 1.562
1.213CysAsp: 1.213 ± 0.615
1.213CysGlu: 1.213 ± 0.622
0.808CysPhe: 0.808 ± 0.649
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.617CysIle: 1.617 ± 1.064
4.042CysLys: 4.042 ± 1.466
1.617CysLeu: 1.617 ± 1.042
0.404CysMet: 0.404 ± 0.328
0.808CysAsn: 0.808 ± 0.353
4.042CysPro: 4.042 ± 2.213
0.808CysGln: 0.808 ± 0.517
0.808CysArg: 0.808 ± 0.372
1.617CysSer: 1.617 ± 1.028
0.404CysThr: 0.404 ± 0.325
2.021CysVal: 2.021 ± 1.069
0.808CysTrp: 0.808 ± 0.372
0.404CysTyr: 0.404 ± 0.328
0.0CysXaa: 0.0 ± 0.0
Asp
1.617AspAla: 1.617 ± 0.745
2.829AspCys: 2.829 ± 0.939
2.425AspAsp: 2.425 ± 0.854
2.425AspGlu: 2.425 ± 0.963
2.829AspPhe: 2.829 ± 1.348
4.446AspGly: 4.446 ± 1.18
0.404AspHis: 0.404 ± 0.324
6.063AspIle: 6.063 ± 1.124
2.425AspLys: 2.425 ± 1.275
5.255AspLeu: 5.255 ± 1.432
0.808AspMet: 0.808 ± 0.417
3.234AspAsn: 3.234 ± 0.65
6.467AspPro: 6.467 ± 2.754
3.638AspGln: 3.638 ± 1.255
4.446AspArg: 4.446 ± 1.45
4.85AspSer: 4.85 ± 1.395
4.85AspThr: 4.85 ± 1.176
6.467AspVal: 6.467 ± 1.895
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.829GluAla: 2.829 ± 0.706
0.404GluCys: 0.404 ± 0.328
6.467GluAsp: 6.467 ± 1.344
11.318GluGlu: 11.318 ± 4.981
2.425GluPhe: 2.425 ± 0.641
4.446GluGly: 4.446 ± 1.454
1.617GluHis: 1.617 ± 0.787
1.213GluIle: 1.213 ± 0.815
5.255GluLys: 5.255 ± 2.922
6.467GluLeu: 6.467 ± 1.457
0.808GluMet: 0.808 ± 0.372
4.042GluAsn: 4.042 ± 0.589
3.638GluPro: 3.638 ± 1.815
2.021GluGln: 2.021 ± 0.816
4.042GluArg: 4.042 ± 2.312
3.234GluSer: 3.234 ± 1.472
5.659GluThr: 5.659 ± 2.287
2.021GluVal: 2.021 ± 0.695
1.213GluTrp: 1.213 ± 0.622
2.021GluTyr: 2.021 ± 0.863
0.0GluXaa: 0.0 ± 0.0
Phe
0.808PheAla: 0.808 ± 0.353
2.829PheCys: 2.829 ± 1.737
3.234PheAsp: 3.234 ± 1.076
4.042PheGlu: 4.042 ± 1.144
2.021PhePhe: 2.021 ± 0.962
2.425PheGly: 2.425 ± 0.97
0.404PheHis: 0.404 ± 0.51
2.021PheIle: 2.021 ± 0.891
3.234PheLys: 3.234 ± 1.077
2.829PheLeu: 2.829 ± 0.588
0.808PheMet: 0.808 ± 0.612
2.425PheAsn: 2.425 ± 1.169
2.425PhePro: 2.425 ± 0.641
1.617PheGln: 1.617 ± 0.657
2.021PheArg: 2.021 ± 0.658
3.638PheSer: 3.638 ± 1.202
2.829PheThr: 2.829 ± 1.2
3.234PheVal: 3.234 ± 0.832
1.617PheTrp: 1.617 ± 0.889
0.404PheTyr: 0.404 ± 0.324
0.0PheXaa: 0.0 ± 0.0
Gly
3.638GlyAla: 3.638 ± 0.776
1.213GlyCys: 1.213 ± 0.361
6.467GlyAsp: 6.467 ± 1.886
4.85GlyGlu: 4.85 ± 1.74
2.425GlyPhe: 2.425 ± 0.978
10.105GlyGly: 10.105 ± 4.665
0.404GlyHis: 0.404 ± 0.325
1.617GlyIle: 1.617 ± 0.575
3.234GlyLys: 3.234 ± 0.978
4.042GlyLeu: 4.042 ± 0.983
0.808GlyMet: 0.808 ± 0.399
4.042GlyAsn: 4.042 ± 1.145
5.659GlyPro: 5.659 ± 2.644
2.829GlyGln: 2.829 ± 0.927
4.042GlyArg: 4.042 ± 1.409
5.659GlySer: 5.659 ± 1.473
4.042GlyThr: 4.042 ± 1.402
4.446GlyVal: 4.446 ± 0.869
0.808GlyTrp: 0.808 ± 0.649
2.021GlyTyr: 2.021 ± 0.6
0.0GlyXaa: 0.0 ± 0.0
His
0.404HisAla: 0.404 ± 0.325
0.808HisCys: 0.808 ± 0.372
1.213HisAsp: 1.213 ± 0.665
0.404HisGlu: 0.404 ± 0.328
2.021HisPhe: 2.021 ± 0.658
0.404HisGly: 0.404 ± 0.324
0.404HisHis: 0.404 ± 0.338
0.808HisIle: 0.808 ± 0.417
0.808HisLys: 0.808 ± 0.372
0.808HisLeu: 0.808 ± 0.353
0.0HisMet: 0.0 ± 0.0
0.404HisAsn: 0.404 ± 0.324
1.213HisPro: 1.213 ± 0.689
0.404HisGln: 0.404 ± 0.328
1.617HisArg: 1.617 ± 0.677
2.021HisSer: 2.021 ± 1.135
1.617HisThr: 1.617 ± 0.703
1.213HisVal: 1.213 ± 0.336
0.808HisTrp: 0.808 ± 0.595
0.404HisTyr: 0.404 ± 0.328
0.0HisXaa: 0.0 ± 0.0
Ile
3.234IleAla: 3.234 ± 1.077
0.808IleCys: 0.808 ± 0.577
4.446IleAsp: 4.446 ± 1.172
2.829IleGlu: 2.829 ± 0.816
2.425IlePhe: 2.425 ± 1.086
3.234IleGly: 3.234 ± 0.687
0.0IleHis: 0.0 ± 0.0
1.617IleIle: 1.617 ± 1.354
0.808IleLys: 0.808 ± 0.372
4.85IleLeu: 4.85 ± 1.731
0.808IleMet: 0.808 ± 0.372
1.213IleAsn: 1.213 ± 0.782
2.021IlePro: 2.021 ± 0.799
0.808IleGln: 0.808 ± 0.353
0.808IleArg: 0.808 ± 0.417
4.85IleSer: 4.85 ± 1.084
2.425IleThr: 2.425 ± 0.929
2.021IleVal: 2.021 ± 0.593
0.0IleTrp: 0.0 ± 0.0
2.021IleTyr: 2.021 ± 0.93
0.0IleXaa: 0.0 ± 0.0
Lys
2.829LysAla: 2.829 ± 1.056
0.808LysCys: 0.808 ± 0.372
4.446LysAsp: 4.446 ± 1.241
5.659LysGlu: 5.659 ± 2.225
2.425LysPhe: 2.425 ± 1.199
2.829LysGly: 2.829 ± 0.886
3.234LysHis: 3.234 ± 1.588
2.829LysIle: 2.829 ± 0.755
5.255LysLys: 5.255 ± 2.049
3.234LysLeu: 3.234 ± 1.255
1.213LysMet: 1.213 ± 0.561
2.425LysAsn: 2.425 ± 1.288
1.213LysPro: 1.213 ± 1.227
1.617LysGln: 1.617 ± 0.575
4.446LysArg: 4.446 ± 1.359
2.829LysSer: 2.829 ± 0.777
4.042LysThr: 4.042 ± 1.017
3.638LysVal: 3.638 ± 1.404
1.213LysTrp: 1.213 ± 0.377
3.638LysTyr: 3.638 ± 1.387
0.0LysXaa: 0.0 ± 0.0
Leu
3.234LeuAla: 3.234 ± 0.934
1.617LeuCys: 1.617 ± 0.8
5.659LeuAsp: 5.659 ± 1.74
5.255LeuGlu: 5.255 ± 2.075
4.042LeuPhe: 4.042 ± 0.906
4.85LeuGly: 4.85 ± 1.121
2.021LeuHis: 2.021 ± 0.665
2.829LeuIle: 2.829 ± 1.326
4.85LeuLys: 4.85 ± 0.947
6.871LeuLeu: 6.871 ± 1.599
1.213LeuMet: 1.213 ± 0.627
3.234LeuAsn: 3.234 ± 0.55
5.255LeuPro: 5.255 ± 1.032
4.85LeuGln: 4.85 ± 0.807
5.255LeuArg: 5.255 ± 2.35
5.255LeuSer: 5.255 ± 0.932
5.255LeuThr: 5.255 ± 0.969
4.042LeuVal: 4.042 ± 1.625
1.213LeuTrp: 1.213 ± 0.792
2.021LeuTyr: 2.021 ± 0.914
0.0LeuXaa: 0.0 ± 0.0
Met
0.808MetAla: 0.808 ± 0.353
0.808MetCys: 0.808 ± 0.353
1.617MetAsp: 1.617 ± 0.588
1.617MetGlu: 1.617 ± 0.703
0.404MetPhe: 0.404 ± 0.328
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.404MetIle: 0.404 ± 0.406
0.808MetLys: 0.808 ± 0.656
0.404MetLeu: 0.404 ± 0.324
0.404MetMet: 0.404 ± 0.324
0.808MetAsn: 0.808 ± 0.43
0.0MetPro: 0.0 ± 0.0
0.808MetGln: 0.808 ± 0.353
1.213MetArg: 1.213 ± 0.659
2.021MetSer: 2.021 ± 0.658
0.404MetThr: 0.404 ± 0.324
0.808MetVal: 0.808 ± 0.656
0.404MetTrp: 0.404 ± 0.328
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.617AsnAla: 1.617 ± 0.899
0.808AsnCys: 0.808 ± 0.353
1.617AsnAsp: 1.617 ± 0.27
2.829AsnGlu: 2.829 ± 0.929
3.234AsnPhe: 3.234 ± 0.528
3.234AsnGly: 3.234 ± 1.545
0.404AsnHis: 0.404 ± 0.359
2.425AsnIle: 2.425 ± 0.995
2.021AsnLys: 2.021 ± 0.724
4.446AsnLeu: 4.446 ± 1.503
1.213AsnMet: 1.213 ± 0.534
1.617AsnAsn: 1.617 ± 0.706
4.042AsnPro: 4.042 ± 1.456
0.0AsnGln: 0.0 ± 0.0
1.213AsnArg: 1.213 ± 0.594
2.829AsnSer: 2.829 ± 0.856
2.021AsnThr: 2.021 ± 0.927
2.425AsnVal: 2.425 ± 0.691
0.808AsnTrp: 0.808 ± 0.353
2.021AsnTyr: 2.021 ± 0.63
0.0AsnXaa: 0.0 ± 0.0
Pro
2.829ProAla: 2.829 ± 1.13
1.213ProCys: 1.213 ± 0.492
4.85ProAsp: 4.85 ± 1.126
5.659ProGlu: 5.659 ± 2.086
1.617ProPhe: 1.617 ± 0.657
4.042ProGly: 4.042 ± 1.195
0.808ProHis: 0.808 ± 0.395
4.446ProIle: 4.446 ± 1.484
5.255ProLys: 5.255 ± 0.897
8.488ProLeu: 8.488 ± 0.798
0.0ProMet: 0.0 ± 0.0
3.234ProAsn: 3.234 ± 0.712
9.701ProPro: 9.701 ± 2.856
1.617ProGln: 1.617 ± 0.835
4.042ProArg: 4.042 ± 1.538
5.659ProSer: 5.659 ± 1.945
5.255ProThr: 5.255 ± 2.353
6.467ProVal: 6.467 ± 1.79
0.404ProTrp: 0.404 ± 0.601
2.425ProTyr: 2.425 ± 1.129
0.0ProXaa: 0.0 ± 0.0
Gln
2.021GlnAla: 2.021 ± 0.495
1.213GlnCys: 1.213 ± 0.617
2.425GlnAsp: 2.425 ± 0.862
3.234GlnGlu: 3.234 ± 0.789
1.617GlnPhe: 1.617 ± 0.941
3.638GlnGly: 3.638 ± 1.417
0.404GlnHis: 0.404 ± 0.394
1.213GlnIle: 1.213 ± 0.336
1.617GlnLys: 1.617 ± 1.023
3.234GlnLeu: 3.234 ± 1.76
0.808GlnMet: 0.808 ± 0.426
2.021GlnAsn: 2.021 ± 0.636
2.829GlnPro: 2.829 ± 1.239
2.425GlnGln: 2.425 ± 1.228
2.021GlnArg: 2.021 ± 0.493
0.808GlnSer: 0.808 ± 0.353
2.021GlnThr: 2.021 ± 0.657
3.234GlnVal: 3.234 ± 0.858
1.213GlnTrp: 1.213 ± 0.815
1.617GlnTyr: 1.617 ± 0.53
0.0GlnXaa: 0.0 ± 0.0
Arg
3.234ArgAla: 3.234 ± 0.747
1.617ArgCys: 1.617 ± 0.588
1.213ArgAsp: 1.213 ± 0.377
4.042ArgGlu: 4.042 ± 1.242
0.808ArgPhe: 0.808 ± 0.417
6.063ArgGly: 6.063 ± 1.56
1.617ArgHis: 1.617 ± 0.696
2.425ArgIle: 2.425 ± 0.856
6.063ArgLys: 6.063 ± 1.103
4.042ArgLeu: 4.042 ± 1.353
0.808ArgMet: 0.808 ± 0.399
1.617ArgAsn: 1.617 ± 0.706
6.871ArgPro: 6.871 ± 1.723
1.617ArgGln: 1.617 ± 0.548
5.255ArgArg: 5.255 ± 1.78
2.829ArgSer: 2.829 ± 0.878
3.234ArgThr: 3.234 ± 1.007
4.85ArgVal: 4.85 ± 1.983
0.0ArgTrp: 0.0 ± 0.0
1.213ArgTyr: 1.213 ± 0.361
0.0ArgXaa: 0.0 ± 0.0
Ser
5.659SerAla: 5.659 ± 1.207
2.021SerCys: 2.021 ± 1.024
3.638SerAsp: 3.638 ± 0.61
2.425SerGlu: 2.425 ± 0.439
4.042SerPhe: 4.042 ± 1.665
6.871SerGly: 6.871 ± 1.411
2.021SerHis: 2.021 ± 0.4
1.213SerIle: 1.213 ± 0.782
2.829SerLys: 2.829 ± 0.856
6.871SerLeu: 6.871 ± 1.967
1.213SerMet: 1.213 ± 0.984
3.234SerAsn: 3.234 ± 0.54
3.638SerPro: 3.638 ± 0.976
3.638SerGln: 3.638 ± 1.426
4.85SerArg: 4.85 ± 1.682
6.871SerSer: 6.871 ± 2.185
6.467SerThr: 6.467 ± 0.937
4.042SerVal: 4.042 ± 1.763
0.404SerTrp: 0.404 ± 0.328
0.808SerTyr: 0.808 ± 0.372
0.0SerXaa: 0.0 ± 0.0
Thr
1.617ThrAla: 1.617 ± 0.662
3.234ThrCys: 3.234 ± 0.509
3.638ThrAsp: 3.638 ± 0.847
4.042ThrGlu: 4.042 ± 1.081
2.021ThrPhe: 2.021 ± 0.972
4.85ThrGly: 4.85 ± 1.317
1.617ThrHis: 1.617 ± 0.922
2.829ThrIle: 2.829 ± 1.152
1.617ThrLys: 1.617 ± 0.703
4.446ThrLeu: 4.446 ± 1.389
0.404ThrMet: 0.404 ± 0.338
2.021ThrAsn: 2.021 ± 1.214
6.871ThrPro: 6.871 ± 1.722
2.021ThrGln: 2.021 ± 0.966
3.638ThrArg: 3.638 ± 0.745
6.871ThrSer: 6.871 ± 1.867
1.617ThrThr: 1.617 ± 0.686
4.85ThrVal: 4.85 ± 1.566
1.213ThrTrp: 1.213 ± 0.472
3.234ThrTyr: 3.234 ± 0.855
0.0ThrXaa: 0.0 ± 0.0
Val
2.021ValAla: 2.021 ± 0.882
0.404ValCys: 0.404 ± 0.406
4.85ValAsp: 4.85 ± 1.402
4.446ValGlu: 4.446 ± 1.612
3.638ValPhe: 3.638 ± 1.467
6.063ValGly: 6.063 ± 1.126
0.808ValHis: 0.808 ± 0.353
0.404ValIle: 0.404 ± 0.325
4.446ValLys: 4.446 ± 1.122
4.85ValLeu: 4.85 ± 1.637
0.404ValMet: 0.404 ± 0.328
1.617ValAsn: 1.617 ± 0.706
5.255ValPro: 5.255 ± 1.333
3.234ValGln: 3.234 ± 0.495
4.446ValArg: 4.446 ± 0.507
6.063ValSer: 6.063 ± 1.163
5.255ValThr: 5.255 ± 2.023
5.255ValVal: 5.255 ± 1.063
0.404ValTrp: 0.404 ± 0.325
2.425ValTyr: 2.425 ± 0.513
0.0ValXaa: 0.0 ± 0.0
Trp
1.213TrpAla: 1.213 ± 0.643
0.404TrpCys: 0.404 ± 0.467
0.404TrpAsp: 0.404 ± 0.325
0.808TrpGlu: 0.808 ± 0.666
1.213TrpPhe: 1.213 ± 0.377
0.808TrpGly: 0.808 ± 0.43
0.0TrpHis: 0.0 ± 0.0
0.404TrpIle: 0.404 ± 0.328
1.213TrpLys: 1.213 ± 0.782
1.213TrpLeu: 1.213 ± 0.599
0.0TrpMet: 0.0 ± 0.0
0.404TrpAsn: 0.404 ± 0.325
0.0TrpPro: 0.0 ± 0.0
1.213TrpGln: 1.213 ± 0.594
1.213TrpArg: 1.213 ± 0.556
0.404TrpSer: 0.404 ± 0.324
2.021TrpThr: 2.021 ± 1.028
1.213TrpVal: 1.213 ± 0.599
0.0TrpTrp: 0.0 ± 0.0
0.404TrpTyr: 0.404 ± 0.324
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.808TyrAla: 0.808 ± 0.656
0.808TyrCys: 0.808 ± 0.934
2.829TyrAsp: 2.829 ± 0.832
2.021TyrGlu: 2.021 ± 0.751
2.829TyrPhe: 2.829 ± 0.876
1.213TyrGly: 1.213 ± 0.594
0.404TyrHis: 0.404 ± 0.325
2.021TyrIle: 2.021 ± 0.816
1.617TyrLys: 1.617 ± 1.011
2.425TyrLeu: 2.425 ± 0.831
0.404TyrMet: 0.404 ± 0.328
1.617TyrAsn: 1.617 ± 0.706
1.617TyrPro: 1.617 ± 0.53
0.808TyrGln: 0.808 ± 0.353
2.021TyrArg: 2.021 ± 0.636
1.617TyrSer: 1.617 ± 0.799
0.808TyrThr: 0.808 ± 0.649
0.808TyrVal: 0.808 ± 0.649
1.213TyrTrp: 1.213 ± 0.617
1.617TyrTyr: 1.617 ± 0.752
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2475 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski