Amino acid dipepetide frequency for Ornithinimicrobium sp. CNJ-824

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.18AlaAla: 19.18 ± 0.221	0.926AlaCys: 0.926 ± 0.037	8.505AlaAsp: 8.505 ± 0.115	8.099AlaGlu: 8.099 ± 0.13	3.024AlaPhe: 3.024 ± 0.064	13.212AlaGly: 13.212 ± 0.155	2.619AlaHis: 2.619 ± 0.061	3.058AlaIle: 3.058 ± 0.072	1.713AlaLys: 1.713 ± 0.058	14.025AlaLeu: 14.025 ± 0.189	2.641AlaMet: 2.641 ± 0.065	1.512AlaAsn: 1.512 ± 0.05	6.459AlaPro: 6.459 ± 0.106	3.914AlaGln: 3.914 ± 0.068	10.802AlaArg: 10.802 ± 0.162	5.58AlaSer: 5.58 ± 0.086	7.418AlaThr: 7.418 ± 0.114	12.721AlaVal: 12.721 ± 0.158	2.184AlaTrp: 2.184 ± 0.054	2.3AlaTyr: 2.3 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	0.771CysAla: 0.771 ± 0.04	0.101CysCys: 0.101 ± 0.012	0.393CysAsp: 0.393 ± 0.023	0.322CysGlu: 0.322 ± 0.021	0.158CysPhe: 0.158 ± 0.015	0.805CysGly: 0.805 ± 0.035	0.175CysHis: 0.175 ± 0.016	0.154CysIle: 0.154 ± 0.015	0.052CysLys: 0.052 ± 0.007	0.564CysLeu: 0.564 ± 0.026	0.096CysMet: 0.096 ± 0.01	0.098CysAsn: 0.098 ± 0.011	0.468CysPro: 0.468 ± 0.027	0.179CysGln: 0.179 ± 0.015	0.558CysArg: 0.558 ± 0.032	0.491CysSer: 0.491 ± 0.029	0.461CysThr: 0.461 ± 0.027	0.485CysVal: 0.485 ± 0.026	0.125CysTrp: 0.125 ± 0.014	0.127CysTyr: 0.127 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	7.288AspAla: 7.288 ± 0.111	0.316AspCys: 0.316 ± 0.021	4.59AspAsp: 4.59 ± 0.096	4.756AspGlu: 4.756 ± 0.084	1.279AspPhe: 1.279 ± 0.038	7.024AspGly: 7.024 ± 0.124	1.637AspHis: 1.637 ± 0.05	1.375AspIle: 1.375 ± 0.049	0.809AspLys: 0.809 ± 0.034	7.563AspLeu: 7.563 ± 0.105	0.776AspMet: 0.776 ± 0.031	0.759AspAsn: 0.759 ± 0.035	5.092AspPro: 5.092 ± 0.083	1.872AspGln: 1.872 ± 0.047	5.745AspArg: 5.745 ± 0.104	1.998AspSer: 1.998 ± 0.061	2.785AspThr: 2.785 ± 0.064	6.324AspVal: 6.324 ± 0.091	0.904AspTrp: 0.904 ± 0.03	1.141AspTyr: 1.141 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	7.634GluAla: 7.634 ± 0.122	0.271GluCys: 0.271 ± 0.02	3.989GluAsp: 3.989 ± 0.087	4.755GluGlu: 4.755 ± 0.085	1.204GluPhe: 1.204 ± 0.043	5.309GluGly: 5.309 ± 0.092	1.886GluHis: 1.886 ± 0.043	1.914GluIle: 1.914 ± 0.061	0.997GluLys: 0.997 ± 0.039	6.725GluLeu: 6.725 ± 0.098	0.963GluMet: 0.963 ± 0.039	0.776GluAsn: 0.776 ± 0.03	3.306GluPro: 3.306 ± 0.082	2.805GluGln: 2.805 ± 0.063	5.477GluArg: 5.477 ± 0.094	2.201GluSer: 2.201 ± 0.058	2.791GluThr: 2.791 ± 0.065	6.22GluVal: 6.22 ± 0.103	0.717GluTrp: 0.717 ± 0.03	0.765GluTyr: 0.765 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.118PheAla: 3.118 ± 0.072	0.191PheCys: 0.191 ± 0.015	1.71PheAsp: 1.71 ± 0.05	1.301PheGlu: 1.301 ± 0.043	0.794PhePhe: 0.794 ± 0.038	2.651PheGly: 2.651 ± 0.07	0.49PheHis: 0.49 ± 0.027	0.616PheIle: 0.616 ± 0.028	0.318PheLys: 0.318 ± 0.018	2.485PheLeu: 2.485 ± 0.062	0.389PheMet: 0.389 ± 0.024	0.429PheAsn: 0.429 ± 0.024	1.149PhePro: 1.149 ± 0.042	0.54PheGln: 0.54 ± 0.025	1.487PheArg: 1.487 ± 0.051	1.207PheSer: 1.207 ± 0.04	1.718PheThr: 1.718 ± 0.044	2.522PheVal: 2.522 ± 0.064	0.437PheTrp: 0.437 ± 0.029	0.526PheTyr: 0.526 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	10.85GlyAla: 10.85 ± 0.145	0.733GlyCys: 0.733 ± 0.034	5.45GlyAsp: 5.45 ± 0.087	5.611GlyGlu: 5.611 ± 0.102	2.484GlyPhe: 2.484 ± 0.067	8.914GlyGly: 8.914 ± 0.142	2.283GlyHis: 2.283 ± 0.057	3.066GlyIle: 3.066 ± 0.071	1.59GlyLys: 1.59 ± 0.054	10.055GlyLeu: 10.055 ± 0.132	2.49GlyMet: 2.49 ± 0.055	1.337GlyAsn: 1.337 ± 0.05	5.765GlyPro: 5.765 ± 0.124	3.094GlyGln: 3.094 ± 0.066	8.771GlyArg: 8.771 ± 0.144	5.245GlySer: 5.245 ± 0.09	6.403GlyThr: 6.403 ± 0.107	8.506GlyVal: 8.506 ± 0.126	2.108GlyTrp: 2.108 ± 0.065	2.051GlyTyr: 2.051 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.734HisAla: 2.734 ± 0.056	0.146HisCys: 0.146 ± 0.014	1.578HisAsp: 1.578 ± 0.049	1.491HisGlu: 1.491 ± 0.046	0.471HisPhe: 0.471 ± 0.023	2.426HisGly: 2.426 ± 0.056	0.714HisHis: 0.714 ± 0.034	0.43HisIle: 0.43 ± 0.024	0.263HisLys: 0.263 ± 0.019	2.859HisLeu: 2.859 ± 0.067	0.283HisMet: 0.283 ± 0.021	0.311HisAsn: 0.311 ± 0.024	1.781HisPro: 1.781 ± 0.045	0.696HisGln: 0.696 ± 0.03	2.23HisArg: 2.23 ± 0.052	0.74HisSer: 0.74 ± 0.029	1.097HisThr: 1.097 ± 0.036	2.257HisVal: 2.257 ± 0.058	0.302HisTrp: 0.302 ± 0.019	0.4HisTyr: 0.4 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	3.507IleAla: 3.507 ± 0.078	0.202IleCys: 0.202 ± 0.018	1.882IleAsp: 1.882 ± 0.053	1.758IleGlu: 1.758 ± 0.051	0.808IlePhe: 0.808 ± 0.036	2.769IleGly: 2.769 ± 0.074	0.478IleHis: 0.478 ± 0.022	0.812IleIle: 0.812 ± 0.036	0.481IleLys: 0.481 ± 0.024	2.358IleLeu: 2.358 ± 0.07	0.42IleMet: 0.42 ± 0.024	0.554IleAsn: 0.554 ± 0.027	1.529IlePro: 1.529 ± 0.052	0.587IleGln: 0.587 ± 0.031	1.641IleArg: 1.641 ± 0.05	1.4IleSer: 1.4 ± 0.051	1.91IleThr: 1.91 ± 0.054	2.607IleVal: 2.607 ± 0.066	0.343IleTrp: 0.343 ± 0.021	0.528IleTyr: 0.528 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	1.704LysAla: 1.704 ± 0.06	0.062LysCys: 0.062 ± 0.009	1.019LysAsp: 1.019 ± 0.042	0.846LysGlu: 0.846 ± 0.038	0.295LysPhe: 0.295 ± 0.02	1.242LysGly: 1.242 ± 0.051	0.342LysHis: 0.342 ± 0.023	0.563LysIle: 0.563 ± 0.028	0.459LysLys: 0.459 ± 0.028	1.173LysLeu: 1.173 ± 0.041	0.3LysMet: 0.3 ± 0.019	0.293LysAsn: 0.293 ± 0.019	0.683LysPro: 0.683 ± 0.036	0.439LysGln: 0.439 ± 0.029	0.885LysArg: 0.885 ± 0.038	0.69LysSer: 0.69 ± 0.032	0.788LysThr: 0.788 ± 0.033	1.431LysVal: 1.431 ± 0.044	0.134LysTrp: 0.134 ± 0.012	0.273LysTyr: 0.273 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	15.723LeuAla: 15.723 ± 0.177	0.557LeuCys: 0.557 ± 0.028	7.066LeuAsp: 7.066 ± 0.12	5.664LeuGlu: 5.664 ± 0.087	2.223LeuPhe: 2.223 ± 0.051	10.393LeuGly: 10.393 ± 0.136	2.299LeuHis: 2.299 ± 0.053	2.333LeuIle: 2.333 ± 0.072	1.176LeuLys: 1.176 ± 0.046	11.882LeuLeu: 11.882 ± 0.171	1.776LeuMet: 1.776 ± 0.052	1.328LeuAsn: 1.328 ± 0.044	6.311LeuPro: 6.311 ± 0.095	2.572LeuGln: 2.572 ± 0.05	8.722LeuArg: 8.722 ± 0.107	5.035LeuSer: 5.035 ± 0.087	6.716LeuThr: 6.716 ± 0.096	11.569LeuVal: 11.569 ± 0.178	1.38LeuTrp: 1.38 ± 0.044	1.399LeuTyr: 1.399 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.466MetAla: 2.466 ± 0.051	0.106MetCys: 0.106 ± 0.011	1.011MetAsp: 1.011 ± 0.033	0.837MetGlu: 0.837 ± 0.038	0.483MetPhe: 0.483 ± 0.024	1.566MetGly: 1.566 ± 0.046	0.369MetHis: 0.369 ± 0.026	0.622MetIle: 0.622 ± 0.025	0.332MetLys: 0.332 ± 0.021	1.921MetLeu: 1.921 ± 0.053	0.364MetMet: 0.364 ± 0.02	0.362MetAsn: 0.362 ± 0.023	1.204MetPro: 1.204 ± 0.041	0.465MetGln: 0.465 ± 0.024	1.465MetArg: 1.465 ± 0.043	1.342MetSer: 1.342 ± 0.045	1.736MetThr: 1.736 ± 0.045	1.758MetVal: 1.758 ± 0.051	0.215MetTrp: 0.215 ± 0.014	0.252MetTyr: 0.252 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	1.642AsnAla: 1.642 ± 0.06	0.107AsnCys: 0.107 ± 0.011	0.819AsnAsp: 0.819 ± 0.034	0.678AsnGlu: 0.678 ± 0.031	0.415AsnPhe: 0.415 ± 0.027	1.184AsnGly: 1.184 ± 0.048	0.337AsnHis: 0.337 ± 0.021	0.473AsnIle: 0.473 ± 0.027	0.241AsnLys: 0.241 ± 0.018	1.46AsnLeu: 1.46 ± 0.048	0.239AsnMet: 0.239 ± 0.018	0.288AsnAsn: 0.288 ± 0.018	1.199AsnPro: 1.199 ± 0.043	0.399AsnGln: 0.399 ± 0.024	0.919AsnArg: 0.919 ± 0.032	0.555AsnSer: 0.555 ± 0.031	0.778AsnThr: 0.778 ± 0.034	1.347AsnVal: 1.347 ± 0.05	0.189AsnTrp: 0.189 ± 0.016	0.323AsnTyr: 0.323 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	7.999ProAla: 7.999 ± 0.138	0.321ProCys: 0.321 ± 0.021	4.593ProAsp: 4.593 ± 0.078	4.348ProGlu: 4.348 ± 0.076	1.41ProPhe: 1.41 ± 0.038	6.879ProGly: 6.879 ± 0.133	1.328ProHis: 1.328 ± 0.045	1.163ProIle: 1.163 ± 0.039	0.645ProLys: 0.645 ± 0.033	4.919ProLeu: 4.919 ± 0.082	1.077ProMet: 1.077 ± 0.036	0.64ProAsn: 0.64 ± 0.029	3.565ProPro: 3.565 ± 0.092	1.871ProGln: 1.871 ± 0.055	4.265ProArg: 4.265 ± 0.073	3.051ProSer: 3.051 ± 0.075	3.731ProThr: 3.731 ± 0.074	6.415ProVal: 6.415 ± 0.11	1.131ProTrp: 1.131 ± 0.042	0.983ProTyr: 0.983 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.899GlnAla: 3.899 ± 0.077	0.135GlnCys: 0.135 ± 0.014	1.861GlnAsp: 1.861 ± 0.048	2.052GlnGlu: 2.052 ± 0.055	0.696GlnPhe: 0.696 ± 0.032	2.437GlnGly: 2.437 ± 0.061	0.745GlnHis: 0.745 ± 0.034	1.036GlnIle: 1.036 ± 0.041	0.382GlnLys: 0.382 ± 0.024	3.196GlnLeu: 3.196 ± 0.062	0.577GlnMet: 0.577 ± 0.025	0.395GlnAsn: 0.395 ± 0.024	1.574GlnPro: 1.574 ± 0.048	1.243GlnGln: 1.243 ± 0.047	2.427GlnArg: 2.427 ± 0.059	0.957GlnSer: 0.957 ± 0.04	1.42GlnThr: 1.42 ± 0.05	3.669GlnVal: 3.669 ± 0.071	0.358GlnTrp: 0.358 ± 0.025	0.38GlnTyr: 0.38 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	10.286ArgAla: 10.286 ± 0.152	0.635ArgCys: 0.635 ± 0.034	4.651ArgAsp: 4.651 ± 0.088	4.79ArgGlu: 4.79 ± 0.085	2.114ArgPhe: 2.114 ± 0.052	6.273ArgGly: 6.273 ± 0.102	2.261ArgHis: 2.261 ± 0.062	2.625ArgIle: 2.625 ± 0.063	1.021ArgLys: 1.021 ± 0.04	8.474ArgLeu: 8.474 ± 0.14	1.959ArgMet: 1.959 ± 0.05	1.015ArgAsn: 1.015 ± 0.034	5.532ArgPro: 5.532 ± 0.101	2.489ArgGln: 2.489 ± 0.06	8.717ArgArg: 8.717 ± 0.153	4.685ArgSer: 4.685 ± 0.079	5.404ArgThr: 5.404 ± 0.089	6.915ArgVal: 6.915 ± 0.099	1.782ArgTrp: 1.782 ± 0.052	1.582ArgTyr: 1.582 ± 0.048	0.0ArgXaa: 0.0 ± 0.0
Ser	5.875SerAla: 5.875 ± 0.091	0.396SerCys: 0.396 ± 0.023	2.427SerAsp: 2.427 ± 0.065	2.169SerGlu: 2.169 ± 0.05	1.353SerPhe: 1.353 ± 0.045	5.126SerGly: 5.126 ± 0.084	0.914SerHis: 0.914 ± 0.034	1.366SerIle: 1.366 ± 0.048	0.64SerLys: 0.64 ± 0.035	4.585SerLeu: 4.585 ± 0.074	1.175SerMet: 1.175 ± 0.04	0.659SerAsn: 0.659 ± 0.029	3.002SerPro: 3.002 ± 0.065	1.211SerGln: 1.211 ± 0.043	3.871SerArg: 3.871 ± 0.076	2.859SerSer: 2.859 ± 0.085	3.547SerThr: 3.547 ± 0.088	4.299SerVal: 4.299 ± 0.08	1.033SerTrp: 1.033 ± 0.038	0.997SerTyr: 0.997 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	7.704ThrAla: 7.704 ± 0.104	0.438ThrCys: 0.438 ± 0.025	3.667ThrAsp: 3.667 ± 0.067	3.076ThrGlu: 3.076 ± 0.06	1.68ThrPhe: 1.68 ± 0.051	6.546ThrGly: 6.546 ± 0.094	1.165ThrHis: 1.165 ± 0.044	1.852ThrIle: 1.852 ± 0.049	0.817ThrLys: 0.817 ± 0.031	5.965ThrLeu: 5.965 ± 0.082	1.062ThrMet: 1.062 ± 0.035	0.899ThrAsn: 0.899 ± 0.037	3.881ThrPro: 3.881 ± 0.065	1.386ThrGln: 1.386 ± 0.041	4.369ThrArg: 4.369 ± 0.073	3.306ThrSer: 3.306 ± 0.072	4.327ThrThr: 4.327 ± 0.089	6.425ThrVal: 6.425 ± 0.106	1.094ThrTrp: 1.094 ± 0.038	1.14ThrTyr: 1.14 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	13.059ValAla: 13.059 ± 0.171	0.648ValCys: 0.648 ± 0.031	6.783ValAsp: 6.783 ± 0.083	6.292ValGlu: 6.292 ± 0.085	2.171ValPhe: 2.171 ± 0.056	9.074ValGly: 9.074 ± 0.117	2.386ValHis: 2.386 ± 0.058	2.282ValIle: 2.282 ± 0.067	1.242ValLys: 1.242 ± 0.051	11.933ValLeu: 11.933 ± 0.166	1.794ValMet: 1.794 ± 0.047	1.346ValAsn: 1.346 ± 0.041	5.979ValPro: 5.979 ± 0.091	2.62ValGln: 2.62 ± 0.054	7.999ValArg: 7.999 ± 0.123	4.455ValSer: 4.455 ± 0.083	5.785ValThr: 5.785 ± 0.084	12.216ValVal: 12.216 ± 0.176	1.362ValTrp: 1.362 ± 0.044	1.418ValTyr: 1.418 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	1.978TrpAla: 1.978 ± 0.051	0.172TrpCys: 0.172 ± 0.015	0.843TrpAsp: 0.843 ± 0.033	0.847TrpGlu: 0.847 ± 0.032	0.521TrpPhe: 0.521 ± 0.026	1.266TrpGly: 1.266 ± 0.046	0.425TrpHis: 0.425 ± 0.023	0.473TrpIle: 0.473 ± 0.025	0.218TrpLys: 0.218 ± 0.017	1.977TrpLeu: 1.977 ± 0.051	0.323TrpMet: 0.323 ± 0.019	0.308TrpAsn: 0.308 ± 0.023	0.829TrpPro: 0.829 ± 0.033	0.56TrpGln: 0.56 ± 0.028	1.458TrpArg: 1.458 ± 0.048	1.024TrpSer: 1.024 ± 0.04	1.067TrpThr: 1.067 ± 0.041	1.496TrpVal: 1.496 ± 0.048	0.488TrpTrp: 0.488 ± 0.026	0.269TrpTyr: 0.269 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.477TyrAla: 2.477 ± 0.058	0.121TyrCys: 0.121 ± 0.011	1.194TyrAsp: 1.194 ± 0.04	1.014TyrGlu: 1.014 ± 0.04	0.494TyrPhe: 0.494 ± 0.026	1.71TyrGly: 1.71 ± 0.051	0.355TyrHis: 0.355 ± 0.021	0.36TyrIle: 0.36 ± 0.025	0.223TyrLys: 0.223 ± 0.018	2.003TyrLeu: 2.003 ± 0.056	0.173TyrMet: 0.173 ± 0.015	0.285TyrAsn: 0.285 ± 0.02	1.025TyrPro: 1.025 ± 0.042	0.499TyrGln: 0.499 ± 0.028	1.402TyrArg: 1.402 ± 0.045	0.682TyrSer: 0.682 ± 0.029	0.918TyrThr: 0.918 ± 0.036	1.662TyrVal: 1.662 ± 0.043	0.258TyrTrp: 0.258 ± 0.017	0.376TyrTyr: 0.376 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2650 proteins (792233 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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