Amino acid dipepetide frequency for Sediminibacillus albus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.729AlaAla: 6.729 ± 0.114	0.566AlaCys: 0.566 ± 0.025	3.982AlaAsp: 3.982 ± 0.066	5.347AlaGlu: 5.347 ± 0.087	3.435AlaPhe: 3.435 ± 0.062	5.959AlaGly: 5.959 ± 0.079	1.221AlaHis: 1.221 ± 0.038	5.805AlaIle: 5.805 ± 0.087	4.461AlaLys: 4.461 ± 0.072	7.089AlaLeu: 7.089 ± 0.086	2.056AlaMet: 2.056 ± 0.048	2.909AlaAsn: 2.909 ± 0.056	2.029AlaPro: 2.029 ± 0.05	2.277AlaGln: 2.277 ± 0.059	2.752AlaArg: 2.752 ± 0.054	4.394AlaSer: 4.394 ± 0.081	3.277AlaThr: 3.277 ± 0.087	5.772AlaVal: 5.772 ± 0.086	0.661AlaTrp: 0.661 ± 0.027	2.438AlaTyr: 2.438 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.377CysAla: 0.377 ± 0.02	0.074CysCys: 0.074 ± 0.01	0.327CysAsp: 0.327 ± 0.018	0.374CysGlu: 0.374 ± 0.017	0.341CysPhe: 0.341 ± 0.02	0.617CysGly: 0.617 ± 0.024	0.183CysHis: 0.183 ± 0.014	0.432CysIle: 0.432 ± 0.021	0.338CysLys: 0.338 ± 0.019	0.646CysLeu: 0.646 ± 0.026	0.157CysMet: 0.157 ± 0.012	0.232CysAsn: 0.232 ± 0.015	0.299CysPro: 0.299 ± 0.017	0.248CysGln: 0.248 ± 0.017	0.287CysArg: 0.287 ± 0.016	0.434CysSer: 0.434 ± 0.02	0.36CysThr: 0.36 ± 0.018	0.327CysVal: 0.327 ± 0.017	0.056CysTrp: 0.056 ± 0.007	0.242CysTyr: 0.242 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.283AspAla: 3.283 ± 0.064	0.342AspCys: 0.342 ± 0.016	2.554AspAsp: 2.554 ± 0.06	4.291AspGlu: 4.291 ± 0.075	2.465AspPhe: 2.465 ± 0.052	3.464AspGly: 3.464 ± 0.073	1.187AspHis: 1.187 ± 0.033	4.352AspIle: 4.352 ± 0.061	3.645AspLys: 3.645 ± 0.062	5.085AspLeu: 5.085 ± 0.076	1.442AspMet: 1.442 ± 0.036	2.354AspAsn: 2.354 ± 0.05	2.121AspPro: 2.121 ± 0.046	2.299AspGln: 2.299 ± 0.048	2.394AspArg: 2.394 ± 0.049	2.924AspSer: 2.924 ± 0.046	2.57AspThr: 2.57 ± 0.046	3.574AspVal: 3.574 ± 0.068	0.719AspTrp: 0.719 ± 0.026	2.374AspTyr: 2.374 ± 0.057	0.0AspXaa: 0.0 ± 0.0
Glu	5.849GluAla: 5.849 ± 0.08	0.314GluCys: 0.314 ± 0.017	4.247GluAsp: 4.247 ± 0.076	7.461GluGlu: 7.461 ± 0.132	2.331GluPhe: 2.331 ± 0.048	4.553GluGly: 4.553 ± 0.079	1.372GluHis: 1.372 ± 0.038	5.625GluIle: 5.625 ± 0.084	6.424GluLys: 6.424 ± 0.094	6.944GluLeu: 6.944 ± 0.093	2.229GluMet: 2.229 ± 0.046	3.79GluAsn: 3.79 ± 0.063	2.034GluPro: 2.034 ± 0.045	3.856GluGln: 3.856 ± 0.075	3.291GluArg: 3.291 ± 0.066	3.653GluSer: 3.653 ± 0.064	4.056GluThr: 4.056 ± 0.071	5.094GluVal: 5.094 ± 0.075	0.833GluTrp: 0.833 ± 0.03	2.222GluTyr: 2.222 ± 0.056	0.0GluXaa: 0.0 ± 0.0
Phe	3.094PheAla: 3.094 ± 0.059	0.327PheCys: 0.327 ± 0.016	2.312PheAsp: 2.312 ± 0.052	2.697PheGlu: 2.697 ± 0.057	2.352PhePhe: 2.352 ± 0.068	3.277PheGly: 3.277 ± 0.068	1.09PheHis: 1.09 ± 0.03	3.758PheIle: 3.758 ± 0.077	2.217PheLys: 2.217 ± 0.051	4.535PheLeu: 4.535 ± 0.091	1.09PheMet: 1.09 ± 0.04	1.793PheAsn: 1.793 ± 0.046	1.739PhePro: 1.739 ± 0.037	1.793PheGln: 1.793 ± 0.051	1.637PheArg: 1.637 ± 0.037	3.41PheSer: 3.41 ± 0.07	2.616PheThr: 2.616 ± 0.052	2.921PheVal: 2.921 ± 0.056	0.517PheTrp: 0.517 ± 0.025	1.712PheTyr: 1.712 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.959GlyAla: 4.959 ± 0.105	0.57GlyCys: 0.57 ± 0.029	3.457GlyAsp: 3.457 ± 0.066	4.87GlyGlu: 4.87 ± 0.078	3.413GlyPhe: 3.413 ± 0.068	4.896GlyGly: 4.896 ± 0.096	1.357GlyHis: 1.357 ± 0.042	5.817GlyIle: 5.817 ± 0.081	4.799GlyLys: 4.799 ± 0.082	6.651GlyLeu: 6.651 ± 0.089	2.167GlyMet: 2.167 ± 0.05	2.894GlyAsn: 2.894 ± 0.058	1.87GlyPro: 1.87 ± 0.069	2.4GlyGln: 2.4 ± 0.051	2.727GlyArg: 2.727 ± 0.058	4.323GlySer: 4.323 ± 0.067	4.043GlyThr: 4.043 ± 0.067	4.824GlyVal: 4.824 ± 0.067	0.843GlyTrp: 0.843 ± 0.028	2.854GlyTyr: 2.854 ± 0.059	0.0GlyXaa: 0.0 ± 0.0
His	1.34HisAla: 1.34 ± 0.037	0.182HisCys: 0.182 ± 0.014	0.985HisAsp: 0.985 ± 0.035	1.239HisGlu: 1.239 ± 0.036	1.043HisPhe: 1.043 ± 0.034	1.462HisGly: 1.462 ± 0.041	0.651HisHis: 0.651 ± 0.031	1.467HisIle: 1.467 ± 0.041	1.085HisLys: 1.085 ± 0.029	2.219HisLeu: 2.219 ± 0.043	0.551HisMet: 0.551 ± 0.021	0.739HisAsn: 0.739 ± 0.029	1.215HisPro: 1.215 ± 0.034	0.99HisGln: 0.99 ± 0.03	0.912HisArg: 0.912 ± 0.029	1.202HisSer: 1.202 ± 0.035	1.077HisThr: 1.077 ± 0.032	1.278HisVal: 1.278 ± 0.033	0.237HisTrp: 0.237 ± 0.016	0.841HisTyr: 0.841 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.034IleAla: 6.034 ± 0.089	0.574IleCys: 0.574 ± 0.026	4.624IleAsp: 4.624 ± 0.069	5.636IleGlu: 5.636 ± 0.079	3.237IlePhe: 3.237 ± 0.079	5.919IleGly: 5.919 ± 0.106	1.657IleHis: 1.657 ± 0.04	5.724IleIle: 5.724 ± 0.089	4.304IleLys: 4.304 ± 0.073	6.8IleLeu: 6.8 ± 0.099	1.64IleMet: 1.64 ± 0.043	3.424IleAsn: 3.424 ± 0.066	3.239IlePro: 3.239 ± 0.058	2.641IleGln: 2.641 ± 0.058	2.906IleArg: 2.906 ± 0.065	5.017IleSer: 5.017 ± 0.075	4.341IleThr: 4.341 ± 0.064	5.089IleVal: 5.089 ± 0.092	0.647IleTrp: 0.647 ± 0.028	2.394IleTyr: 2.394 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	4.578LysAla: 4.578 ± 0.081	0.259LysCys: 0.259 ± 0.015	3.741LysAsp: 3.741 ± 0.054	6.252LysGlu: 6.252 ± 0.091	1.819LysPhe: 1.819 ± 0.04	4.154LysGly: 4.154 ± 0.073	1.379LysHis: 1.379 ± 0.037	4.196LysIle: 4.196 ± 0.065	5.216LysLys: 5.216 ± 0.09	5.512LysLeu: 5.512 ± 0.071	1.935LysMet: 1.935 ± 0.039	3.197LysAsn: 3.197 ± 0.057	2.087LysPro: 2.087 ± 0.047	4.019LysGln: 4.019 ± 0.078	3.124LysArg: 3.124 ± 0.053	3.379LysSer: 3.379 ± 0.058	3.363LysThr: 3.363 ± 0.062	4.306LysVal: 4.306 ± 0.079	0.704LysTrp: 0.704 ± 0.024	2.051LysTyr: 2.051 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	7.888LeuAla: 7.888 ± 0.09	0.568LeuCys: 0.568 ± 0.02	5.004LeuAsp: 5.004 ± 0.078	6.769LeuGlu: 6.769 ± 0.085	4.829LeuPhe: 4.829 ± 0.095	6.319LeuGly: 6.319 ± 0.096	1.997LeuHis: 1.997 ± 0.044	7.163LeuIle: 7.163 ± 0.118	6.051LeuLys: 6.051 ± 0.085	10.524LeuLeu: 10.524 ± 0.18	2.47LeuMet: 2.47 ± 0.043	4.078LeuAsn: 4.078 ± 0.059	4.072LeuPro: 4.072 ± 0.063	3.788LeuGln: 3.788 ± 0.067	3.498LeuArg: 3.498 ± 0.066	6.683LeuSer: 6.683 ± 0.091	5.526LeuThr: 5.526 ± 0.073	6.326LeuVal: 6.326 ± 0.083	0.869LeuTrp: 0.869 ± 0.029	3.067LeuTyr: 3.067 ± 0.062	0.0LeuXaa: 0.0 ± 0.0
Met	2.256MetAla: 2.256 ± 0.05	0.122MetCys: 0.122 ± 0.01	1.599MetAsp: 1.599 ± 0.039	2.324MetGlu: 2.324 ± 0.043	1.033MetPhe: 1.033 ± 0.036	1.751MetGly: 1.751 ± 0.038	0.392MetHis: 0.392 ± 0.02	1.985MetIle: 1.985 ± 0.047	2.272MetLys: 2.272 ± 0.052	2.554MetLeu: 2.554 ± 0.05	0.793MetMet: 0.793 ± 0.031	1.448MetAsn: 1.448 ± 0.04	1.025MetPro: 1.025 ± 0.036	0.905MetGln: 0.905 ± 0.033	1.029MetArg: 1.029 ± 0.035	1.518MetSer: 1.518 ± 0.043	1.479MetThr: 1.479 ± 0.039	1.856MetVal: 1.856 ± 0.046	0.158MetTrp: 0.158 ± 0.013	0.684MetTyr: 0.684 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	2.518AsnAla: 2.518 ± 0.056	0.257AsnCys: 0.257 ± 0.014	2.276AsnAsp: 2.276 ± 0.052	3.274AsnGlu: 3.274 ± 0.059	1.675AsnPhe: 1.675 ± 0.042	3.224AsnGly: 3.224 ± 0.059	1.104AsnHis: 1.104 ± 0.036	3.404AsnIle: 3.404 ± 0.063	3.055AsnLys: 3.055 ± 0.056	3.715AsnLeu: 3.715 ± 0.072	1.171AsnMet: 1.171 ± 0.034	2.24AsnAsn: 2.24 ± 0.056	2.089AsnPro: 2.089 ± 0.05	2.344AsnGln: 2.344 ± 0.053	2.066AsnArg: 2.066 ± 0.044	2.388AsnSer: 2.388 ± 0.055	2.175AsnThr: 2.175 ± 0.05	2.723AsnVal: 2.723 ± 0.053	0.571AsnTrp: 0.571 ± 0.025	1.709AsnTyr: 1.709 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	2.748ProAla: 2.748 ± 0.056	0.205ProCys: 0.205 ± 0.013	2.278ProAsp: 2.278 ± 0.045	3.346ProGlu: 3.346 ± 0.063	1.963ProPhe: 1.963 ± 0.05	2.588ProGly: 2.588 ± 0.057	0.746ProHis: 0.746 ± 0.029	2.618ProIle: 2.618 ± 0.056	1.913ProLys: 1.913 ± 0.045	3.461ProLeu: 3.461 ± 0.058	0.848ProMet: 0.848 ± 0.033	1.517ProAsn: 1.517 ± 0.04	1.013ProPro: 1.013 ± 0.033	1.171ProGln: 1.171 ± 0.035	1.147ProArg: 1.147 ± 0.037	2.231ProSer: 2.231 ± 0.046	1.827ProThr: 1.827 ± 0.063	3.014ProVal: 3.014 ± 0.056	0.396ProTrp: 0.396 ± 0.019	1.435ProTyr: 1.435 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	3.378GlnAla: 3.378 ± 0.059	0.175GlnCys: 0.175 ± 0.012	1.969GlnAsp: 1.969 ± 0.047	3.447GlnGlu: 3.447 ± 0.07	1.672GlnPhe: 1.672 ± 0.045	2.482GlnGly: 2.482 ± 0.055	0.792GlnHis: 0.792 ± 0.028	2.593GlnIle: 2.593 ± 0.049	2.715GlnLys: 2.715 ± 0.061	4.629GlnLeu: 4.629 ± 0.077	1.29GlnMet: 1.29 ± 0.036	1.59GlnAsn: 1.59 ± 0.039	1.519GlnPro: 1.519 ± 0.043	2.383GlnGln: 2.383 ± 0.062	1.65GlnArg: 1.65 ± 0.046	2.351GlnSer: 2.351 ± 0.053	2.29GlnThr: 2.29 ± 0.048	2.691GlnVal: 2.691 ± 0.051	0.49GlnTrp: 0.49 ± 0.02	1.329GlnTyr: 1.329 ± 0.04	0.0GlnXaa: 0.0 ± 0.0
Arg	2.433ArgAla: 2.433 ± 0.051	0.244ArgCys: 0.244 ± 0.015	1.985ArgAsp: 1.985 ± 0.044	3.182ArgGlu: 3.182 ± 0.062	1.924ArgPhe: 1.924 ± 0.046	2.36ArgGly: 2.36 ± 0.054	0.767ArgHis: 0.767 ± 0.026	2.924ArgIle: 2.924 ± 0.059	3.153ArgLys: 3.153 ± 0.05	4.198ArgLeu: 4.198 ± 0.07	1.348ArgMet: 1.348 ± 0.039	1.889ArgAsn: 1.889 ± 0.043	1.333ArgPro: 1.333 ± 0.039	1.769ArgGln: 1.769 ± 0.044	1.874ArgArg: 1.874 ± 0.048	2.293ArgSer: 2.293 ± 0.05	2.018ArgThr: 2.018 ± 0.052	2.506ArgVal: 2.506 ± 0.053	0.456ArgTrp: 0.456 ± 0.022	1.494ArgTyr: 1.494 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	4.059SerAla: 4.059 ± 0.071	0.391SerCys: 0.391 ± 0.023	2.988SerAsp: 2.988 ± 0.062	4.016SerGlu: 4.016 ± 0.061	3.329SerPhe: 3.329 ± 0.064	4.615SerGly: 4.615 ± 0.071	1.303SerHis: 1.303 ± 0.043	4.824SerIle: 4.824 ± 0.074	3.596SerLys: 3.596 ± 0.059	6.35SerLeu: 6.35 ± 0.095	1.698SerMet: 1.698 ± 0.038	2.626SerAsn: 2.626 ± 0.053	2.157SerPro: 2.157 ± 0.046	2.242SerGln: 2.242 ± 0.046	2.429SerArg: 2.429 ± 0.047	4.142SerSer: 4.142 ± 0.076	3.007SerThr: 3.007 ± 0.055	4.132SerVal: 4.132 ± 0.063	0.686SerTrp: 0.686 ± 0.032	2.357SerTyr: 2.357 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	4.318ThrAla: 4.318 ± 0.065	0.337ThrCys: 0.337 ± 0.018	2.811ThrAsp: 2.811 ± 0.058	3.781ThrGlu: 3.781 ± 0.064	2.486ThrPhe: 2.486 ± 0.055	4.529ThrGly: 4.529 ± 0.141	1.007ThrHis: 1.007 ± 0.03	4.34ThrIle: 4.34 ± 0.074	2.967ThrLys: 2.967 ± 0.054	4.914ThrLeu: 4.914 ± 0.072	1.331ThrMet: 1.331 ± 0.037	2.317ThrAsn: 2.317 ± 0.052	2.151ThrPro: 2.151 ± 0.046	1.369ThrGln: 1.369 ± 0.035	1.79ThrArg: 1.79 ± 0.045	3.25ThrSer: 3.25 ± 0.058	2.743ThrThr: 2.743 ± 0.06	4.109ThrVal: 4.109 ± 0.067	0.499ThrTrp: 0.499 ± 0.027	1.88ThrTyr: 1.88 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	4.582ValAla: 4.582 ± 0.065	0.532ValCys: 0.532 ± 0.023	3.86ValAsp: 3.86 ± 0.066	4.874ValGlu: 4.874 ± 0.073	3.186ValPhe: 3.186 ± 0.058	4.374ValGly: 4.374 ± 0.078	1.347ValHis: 1.347 ± 0.038	5.645ValIle: 5.645 ± 0.072	4.295ValLys: 4.295 ± 0.065	6.754ValLeu: 6.754 ± 0.084	1.723ValMet: 1.723 ± 0.04	3.022ValAsn: 3.022 ± 0.057	2.676ValPro: 2.676 ± 0.053	2.301ValGln: 2.301 ± 0.048	2.57ValArg: 2.57 ± 0.048	4.628ValSer: 4.628 ± 0.062	3.917ValThr: 3.917 ± 0.061	4.736ValVal: 4.736 ± 0.079	0.646ValTrp: 0.646 ± 0.027	2.327ValTyr: 2.327 ± 0.054	0.0ValXaa: 0.0 ± 0.0
Trp	0.605TrpAla: 0.605 ± 0.023	0.06TrpCys: 0.06 ± 0.008	0.533TrpAsp: 0.533 ± 0.025	0.737TrpGlu: 0.737 ± 0.026	0.529TrpPhe: 0.529 ± 0.025	0.685TrpGly: 0.685 ± 0.026	0.211TrpHis: 0.211 ± 0.018	0.824TrpIle: 0.824 ± 0.029	0.783TrpLys: 0.783 ± 0.029	1.256TrpLeu: 1.256 ± 0.038	0.374TrpMet: 0.374 ± 0.017	0.528TrpAsn: 0.528 ± 0.022	0.308TrpPro: 0.308 ± 0.017	0.47TrpGln: 0.47 ± 0.023	0.432TrpArg: 0.432 ± 0.021	0.583TrpSer: 0.583 ± 0.026	0.54TrpThr: 0.54 ± 0.025	0.617TrpVal: 0.617 ± 0.023	0.169TrpTrp: 0.169 ± 0.013	0.355TrpTyr: 0.355 ± 0.022	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.132TyrAla: 2.132 ± 0.051	0.251TyrCys: 0.251 ± 0.015	1.905TyrAsp: 1.905 ± 0.049	2.261TyrGlu: 2.261 ± 0.049	1.821TyrPhe: 1.821 ± 0.042	2.505TyrGly: 2.505 ± 0.048	0.953TyrHis: 0.953 ± 0.033	2.353TyrIle: 2.353 ± 0.053	1.983TyrLys: 1.983 ± 0.047	3.654TyrLeu: 3.654 ± 0.069	0.868TyrMet: 0.868 ± 0.033	1.393TyrAsn: 1.393 ± 0.04	1.488TyrPro: 1.488 ± 0.039	2.175TyrGln: 2.175 ± 0.049	1.632TyrArg: 1.632 ± 0.041	2.145TyrSer: 2.145 ± 0.051	1.702TyrThr: 1.702 ± 0.049	2.102TyrVal: 2.102 ± 0.052	0.443TyrTrp: 0.443 ± 0.024	1.487TyrTyr: 1.487 ± 0.05	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3476 proteins (992148 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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