Amino acid dipepetide frequency for Heterobasidion partitivirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.05AlaAla: 9.05 ± 3.143
0.905AlaCys: 0.905 ± 0.647
8.145AlaAsp: 8.145 ± 0.329
0.905AlaGlu: 0.905 ± 0.647
3.62AlaPhe: 3.62 ± 0.159
5.43AlaGly: 5.43 ± 4.356
0.905AlaHis: 0.905 ± 0.726
1.81AlaIle: 1.81 ± 1.452
4.525AlaLys: 4.525 ± 0.488
6.335AlaLeu: 6.335 ± 2.337
3.62AlaMet: 3.62 ± 0.159
2.715AlaAsn: 2.715 ± 2.178
1.81AlaPro: 1.81 ± 1.452
3.62AlaGln: 3.62 ± 1.214
8.145AlaArg: 8.145 ± 1.044
7.24AlaSer: 7.24 ± 0.318
1.81AlaThr: 1.81 ± 1.452
2.715AlaVal: 2.715 ± 2.178
0.0AlaTrp: 0.0 ± 0.0
2.715AlaTyr: 2.715 ± 0.567
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.905CysGlu: 0.905 ± 0.726
1.81CysPhe: 1.81 ± 0.079
1.81CysGly: 1.81 ± 0.079
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.905CysPro: 0.905 ± 0.726
0.905CysGln: 0.905 ± 0.726
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.81CysTyr: 1.81 ± 1.293
0.0CysXaa: 0.0 ± 0.0
Asp
9.05AspAla: 9.05 ± 0.397
0.905AspCys: 0.905 ± 0.726
3.62AspAsp: 3.62 ± 2.586
0.905AspGlu: 0.905 ± 0.726
2.715AspPhe: 2.715 ± 0.567
0.0AspGly: 0.0 ± 0.0
2.715AspHis: 2.715 ± 1.94
2.715AspIle: 2.715 ± 0.567
2.715AspLys: 2.715 ± 1.94
6.335AspLeu: 6.335 ± 0.408
2.715AspMet: 2.715 ± 0.806
2.715AspAsn: 2.715 ± 0.806
3.62AspPro: 3.62 ± 1.214
3.62AspGln: 3.62 ± 0.159
1.81AspArg: 1.81 ± 0.079
5.43AspSer: 5.43 ± 2.507
0.905AspThr: 0.905 ± 0.647
3.62AspVal: 3.62 ± 0.159
1.81AspTrp: 1.81 ± 1.293
1.81AspTyr: 1.81 ± 0.079
0.0AspXaa: 0.0 ± 0.0
Glu
1.81GluAla: 1.81 ± 1.452
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
2.715GluGlu: 2.715 ± 0.567
2.715GluPhe: 2.715 ± 0.567
0.905GluGly: 0.905 ± 0.726
2.715GluHis: 2.715 ± 1.94
1.81GluIle: 1.81 ± 0.079
0.905GluLys: 0.905 ± 0.647
2.715GluLeu: 2.715 ± 2.178
0.0GluMet: 0.0 ± 0.0
0.905GluAsn: 0.905 ± 0.726
1.81GluPro: 1.81 ± 1.293
0.905GluGln: 0.905 ± 0.726
1.81GluArg: 1.81 ± 1.293
1.81GluSer: 1.81 ± 0.079
3.62GluThr: 3.62 ± 0.159
3.62GluVal: 3.62 ± 2.586
0.0GluTrp: 0.0 ± 0.0
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
6.335PheAla: 6.335 ± 0.408
0.905PheCys: 0.905 ± 0.726
7.24PheAsp: 7.24 ± 1.055
4.525PheGlu: 4.525 ± 0.488
3.62PhePhe: 3.62 ± 0.159
4.525PheGly: 4.525 ± 0.488
0.0PheHis: 0.0 ± 0.0
2.715PheIle: 2.715 ± 0.806
2.715PheLys: 2.715 ± 1.94
6.335PheLeu: 6.335 ± 2.337
2.715PheMet: 2.715 ± 1.645
0.905PheAsn: 0.905 ± 0.647
1.81PhePro: 1.81 ± 1.293
1.81PheGln: 1.81 ± 0.079
4.525PheArg: 4.525 ± 1.86
2.715PheSer: 2.715 ± 0.806
5.43PheThr: 5.43 ± 1.134
4.525PheVal: 4.525 ± 0.488
2.715PheTrp: 2.715 ± 0.806
1.81PheTyr: 1.81 ± 0.079
0.0PheXaa: 0.0 ± 0.0
Gly
0.905GlyAla: 0.905 ± 0.726
0.905GlyCys: 0.905 ± 0.726
1.81GlyAsp: 1.81 ± 1.293
3.62GlyGlu: 3.62 ± 1.532
6.335GlyPhe: 6.335 ± 1.781
2.715GlyGly: 2.715 ± 0.806
2.715GlyHis: 2.715 ± 0.806
1.81GlyIle: 1.81 ± 1.452
1.81GlyLys: 1.81 ± 0.079
5.43GlyLeu: 5.43 ± 0.238
0.905GlyMet: 0.905 ± 0.647
2.715GlyAsn: 2.715 ± 0.567
2.715GlyPro: 2.715 ± 2.178
2.715GlyGln: 2.715 ± 2.178
3.62GlyArg: 3.62 ± 1.532
2.715GlySer: 2.715 ± 0.806
0.905GlyThr: 0.905 ± 0.726
2.715GlyVal: 2.715 ± 0.806
0.0GlyTrp: 0.0 ± 0.0
4.525GlyTyr: 4.525 ± 1.86
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.905HisCys: 0.905 ± 0.647
1.81HisAsp: 1.81 ± 1.293
0.905HisGlu: 0.905 ± 0.726
2.715HisPhe: 2.715 ± 1.94
0.905HisGly: 0.905 ± 0.647
1.81HisHis: 1.81 ± 0.079
2.715HisIle: 2.715 ± 0.567
0.0HisLys: 0.0 ± 0.0
4.525HisLeu: 4.525 ± 0.488
0.905HisMet: 0.905 ± 0.647
1.81HisAsn: 1.81 ± 1.293
4.525HisPro: 4.525 ± 1.86
0.905HisGln: 0.905 ± 0.726
0.0HisArg: 0.0 ± 0.0
1.81HisSer: 1.81 ± 1.452
1.81HisThr: 1.81 ± 0.079
1.81HisVal: 1.81 ± 1.293
0.0HisTrp: 0.0 ± 0.0
2.715HisTyr: 2.715 ± 1.94
0.0HisXaa: 0.0 ± 0.0
Ile
2.715IleAla: 2.715 ± 0.806
0.905IleCys: 0.905 ± 0.726
4.525IleAsp: 4.525 ± 0.488
0.905IleGlu: 0.905 ± 0.647
2.715IlePhe: 2.715 ± 0.567
0.0IleGly: 0.0 ± 0.0
2.715IleHis: 2.715 ± 1.94
0.905IleIle: 0.905 ± 0.647
3.62IleLys: 3.62 ± 1.214
5.43IleLeu: 5.43 ± 1.134
2.715IleMet: 2.715 ± 0.567
4.525IleAsn: 4.525 ± 2.258
3.62IlePro: 3.62 ± 0.159
1.81IleGln: 1.81 ± 0.079
1.81IleArg: 1.81 ± 1.293
0.905IleSer: 0.905 ± 0.647
4.525IleThr: 4.525 ± 0.488
1.81IleVal: 1.81 ± 1.452
0.0IleTrp: 0.0 ± 0.0
2.715IleTyr: 2.715 ± 1.94
0.0IleXaa: 0.0 ± 0.0
Lys
2.715LysAla: 2.715 ± 0.567
0.0LysCys: 0.0 ± 0.0
0.905LysAsp: 0.905 ± 0.647
0.905LysGlu: 0.905 ± 0.726
4.525LysPhe: 4.525 ± 0.488
2.715LysGly: 2.715 ± 0.567
1.81LysHis: 1.81 ± 0.079
5.43LysIle: 5.43 ± 3.879
2.715LysLys: 2.715 ± 0.567
2.715LysLeu: 2.715 ± 0.567
1.81LysMet: 1.81 ± 0.079
1.81LysAsn: 1.81 ± 0.079
1.81LysPro: 1.81 ± 1.293
2.715LysGln: 2.715 ± 2.178
0.905LysArg: 0.905 ± 0.647
3.62LysSer: 3.62 ± 0.159
2.715LysThr: 2.715 ± 1.94
1.81LysVal: 1.81 ± 1.293
1.81LysTrp: 1.81 ± 1.293
2.715LysTyr: 2.715 ± 0.567
0.0LysXaa: 0.0 ± 0.0
Leu
6.335LeuAla: 6.335 ± 0.965
0.0LeuCys: 0.0 ± 0.0
3.62LeuAsp: 3.62 ± 1.532
0.905LeuGlu: 0.905 ± 0.726
6.335LeuPhe: 6.335 ± 1.781
5.43LeuGly: 5.43 ± 1.611
2.715LeuHis: 2.715 ± 0.806
7.24LeuIle: 7.24 ± 1.055
6.335LeuLys: 6.335 ± 0.408
6.335LeuLeu: 6.335 ± 0.965
2.715LeuMet: 2.715 ± 0.567
5.43LeuAsn: 5.43 ± 2.984
6.335LeuPro: 6.335 ± 1.781
1.81LeuGln: 1.81 ± 0.079
4.525LeuArg: 4.525 ± 0.488
8.145LeuSer: 8.145 ± 3.789
3.62LeuThr: 3.62 ± 1.214
5.43LeuVal: 5.43 ± 0.238
2.715LeuTrp: 2.715 ± 1.94
3.62LeuTyr: 3.62 ± 1.214
0.0LeuXaa: 0.0 ± 0.0
Met
2.715MetAla: 2.715 ± 0.567
0.0MetCys: 0.0 ± 0.0
2.715MetAsp: 2.715 ± 0.806
0.905MetGlu: 0.905 ± 0.647
2.715MetPhe: 2.715 ± 0.806
0.905MetGly: 0.905 ± 0.647
0.0MetHis: 0.0 ± 0.0
2.715MetIle: 2.715 ± 1.94
1.81MetLys: 1.81 ± 1.293
2.715MetLeu: 2.715 ± 0.806
0.0MetMet: 0.0 ± 0.0
0.905MetAsn: 0.905 ± 0.726
1.81MetPro: 1.81 ± 0.079
0.0MetGln: 0.0 ± 0.0
1.81MetArg: 1.81 ± 0.079
3.62MetSer: 3.62 ± 2.904
1.81MetThr: 1.81 ± 0.079
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.62AsnAla: 3.62 ± 2.904
0.0AsnCys: 0.0 ± 0.0
1.81AsnAsp: 1.81 ± 1.293
2.715AsnGlu: 2.715 ± 0.567
0.905AsnPhe: 0.905 ± 0.647
3.62AsnGly: 3.62 ± 0.159
0.0AsnHis: 0.0 ± 0.0
0.905AsnIle: 0.905 ± 0.726
0.0AsnLys: 0.0 ± 0.0
9.05AsnLeu: 9.05 ± 0.975
2.715AsnMet: 2.715 ± 2.561
6.335AsnAsn: 6.335 ± 0.408
5.43AsnPro: 5.43 ± 2.984
2.715AsnGln: 2.715 ± 0.806
0.905AsnArg: 0.905 ± 0.726
1.81AsnSer: 1.81 ± 0.079
3.62AsnThr: 3.62 ± 2.904
4.525AsnVal: 4.525 ± 0.885
1.81AsnTrp: 1.81 ± 1.293
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
6.335ProAla: 6.335 ± 2.337
0.0ProCys: 0.0 ± 0.0
5.43ProAsp: 5.43 ± 0.238
0.905ProGlu: 0.905 ± 0.647
6.335ProPhe: 6.335 ± 2.337
2.715ProGly: 2.715 ± 0.806
2.715ProHis: 2.715 ± 0.567
3.62ProIle: 3.62 ± 0.159
2.715ProLys: 2.715 ± 0.567
3.62ProLeu: 3.62 ± 0.159
0.905ProMet: 0.905 ± 0.726
3.62ProAsn: 3.62 ± 0.159
2.715ProPro: 2.715 ± 0.806
0.905ProGln: 0.905 ± 0.726
3.62ProArg: 3.62 ± 2.586
5.43ProSer: 5.43 ± 0.238
4.525ProThr: 4.525 ± 1.86
5.43ProVal: 5.43 ± 0.238
0.0ProTrp: 0.0 ± 0.0
3.62ProTyr: 3.62 ± 0.159
0.0ProXaa: 0.0 ± 0.0
Gln
1.81GlnAla: 1.81 ± 0.079
0.905GlnCys: 0.905 ± 0.726
0.905GlnAsp: 0.905 ± 0.647
0.905GlnGlu: 0.905 ± 0.647
1.81GlnPhe: 1.81 ± 0.079
2.715GlnGly: 2.715 ± 0.806
2.715GlnHis: 2.715 ± 0.567
0.905GlnIle: 0.905 ± 0.726
2.715GlnLys: 2.715 ± 0.806
3.62GlnLeu: 3.62 ± 0.159
0.0GlnMet: 0.0 ± 0.0
3.62GlnAsn: 3.62 ± 2.904
0.905GlnPro: 0.905 ± 0.726
2.715GlnGln: 2.715 ± 0.806
3.62GlnArg: 3.62 ± 1.214
1.81GlnSer: 1.81 ± 0.079
1.81GlnThr: 1.81 ± 0.079
3.62GlnVal: 3.62 ± 1.532
0.905GlnTrp: 0.905 ± 0.726
2.715GlnTyr: 2.715 ± 0.806
0.0GlnXaa: 0.0 ± 0.0
Arg
0.905ArgAla: 0.905 ± 0.726
0.0ArgCys: 0.0 ± 0.0
3.62ArgAsp: 3.62 ± 2.586
0.905ArgGlu: 0.905 ± 0.647
2.715ArgPhe: 2.715 ± 0.806
1.81ArgGly: 1.81 ± 1.452
2.715ArgHis: 2.715 ± 0.567
0.905ArgIle: 0.905 ± 0.726
1.81ArgLys: 1.81 ± 0.079
8.145ArgLeu: 8.145 ± 1.701
0.905ArgMet: 0.905 ± 0.647
3.62ArgAsn: 3.62 ± 1.532
6.335ArgPro: 6.335 ± 0.408
0.905ArgGln: 0.905 ± 0.726
0.905ArgArg: 0.905 ± 0.647
2.715ArgSer: 2.715 ± 1.94
4.525ArgThr: 4.525 ± 1.86
4.525ArgVal: 4.525 ± 0.885
0.0ArgTrp: 0.0 ± 0.0
1.81ArgTyr: 1.81 ± 1.293
0.0ArgXaa: 0.0 ± 0.0
Ser
3.62SerAla: 3.62 ± 1.532
0.905SerCys: 0.905 ± 0.647
2.715SerAsp: 2.715 ± 0.806
1.81SerGlu: 1.81 ± 0.079
5.43SerPhe: 5.43 ± 0.238
6.335SerGly: 6.335 ± 0.965
0.905SerHis: 0.905 ± 0.647
5.43SerIle: 5.43 ± 1.134
5.43SerLys: 5.43 ± 0.238
4.525SerLeu: 4.525 ± 1.86
0.905SerMet: 0.905 ± 0.726
0.905SerAsn: 0.905 ± 0.726
2.715SerPro: 2.715 ± 0.567
5.43SerGln: 5.43 ± 1.611
2.715SerArg: 2.715 ± 0.806
8.145SerSer: 8.145 ± 5.162
1.81SerThr: 1.81 ± 0.079
5.43SerVal: 5.43 ± 2.984
4.525SerTrp: 4.525 ± 0.885
2.715SerTyr: 2.715 ± 0.567
0.0SerXaa: 0.0 ± 0.0
Thr
5.43ThrAla: 5.43 ± 1.611
0.0ThrCys: 0.0 ± 0.0
4.525ThrAsp: 4.525 ± 1.86
1.81ThrGlu: 1.81 ± 1.293
1.81ThrPhe: 1.81 ± 0.079
5.43ThrGly: 5.43 ± 0.238
0.905ThrHis: 0.905 ± 0.647
2.715ThrIle: 2.715 ± 0.567
3.62ThrLys: 3.62 ± 1.214
3.62ThrLeu: 3.62 ± 0.159
0.905ThrMet: 0.905 ± 0.726
4.525ThrAsn: 4.525 ± 1.86
3.62ThrPro: 3.62 ± 2.904
2.715ThrGln: 2.715 ± 0.567
4.525ThrArg: 4.525 ± 0.885
5.43ThrSer: 5.43 ± 1.611
1.81ThrThr: 1.81 ± 0.079
1.81ThrVal: 1.81 ± 0.079
0.0ThrTrp: 0.0 ± 0.0
3.62ThrTyr: 3.62 ± 2.586
0.0ThrXaa: 0.0 ± 0.0
Val
7.24ValAla: 7.24 ± 3.063
0.905ValCys: 0.905 ± 0.647
4.525ValAsp: 4.525 ± 0.885
3.62ValGlu: 3.62 ± 1.214
2.715ValPhe: 2.715 ± 0.567
1.81ValGly: 1.81 ± 0.079
0.905ValHis: 0.905 ± 0.647
1.81ValIle: 1.81 ± 1.293
0.905ValLys: 0.905 ± 0.647
4.525ValLeu: 4.525 ± 0.885
1.81ValMet: 1.81 ± 0.079
1.81ValAsn: 1.81 ± 1.452
9.05ValPro: 9.05 ± 3.143
0.905ValGln: 0.905 ± 0.647
3.62ValArg: 3.62 ± 0.159
2.715ValSer: 2.715 ± 0.567
5.43ValThr: 5.43 ± 0.238
0.905ValVal: 0.905 ± 0.726
0.0ValTrp: 0.0 ± 0.0
1.81ValTyr: 1.81 ± 0.079
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.905TrpGly: 0.905 ± 0.647
1.81TrpHis: 1.81 ± 1.293
0.0TrpIle: 0.0 ± 0.0
0.905TrpLys: 0.905 ± 0.647
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.715TrpAsn: 2.715 ± 0.567
1.81TrpPro: 1.81 ± 1.293
1.81TrpGln: 1.81 ± 0.079
0.905TrpArg: 0.905 ± 0.647
0.905TrpSer: 0.905 ± 0.647
3.62TrpThr: 3.62 ± 1.532
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.905TrpTyr: 0.905 ± 0.726
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.43TyrAla: 5.43 ± 1.134
0.0TyrCys: 0.0 ± 0.0
1.81TyrAsp: 1.81 ± 0.079
0.0TyrGlu: 0.0 ± 0.0
6.335TyrPhe: 6.335 ± 1.781
0.905TyrGly: 0.905 ± 0.647
1.81TyrHis: 1.81 ± 1.293
2.715TyrIle: 2.715 ± 0.567
0.905TyrLys: 0.905 ± 0.647
3.62TyrLeu: 3.62 ± 0.159
0.0TyrMet: 0.0 ± 0.0
1.81TyrAsn: 1.81 ± 1.293
1.81TyrPro: 1.81 ± 1.293
1.81TyrGln: 1.81 ± 1.293
0.0TyrArg: 0.0 ± 0.0
5.43TyrSer: 5.43 ± 0.238
4.525TyrThr: 4.525 ± 0.488
2.715TyrVal: 2.715 ± 1.94
0.0TyrTrp: 0.0 ± 0.0
7.24TyrTyr: 7.24 ± 0.318
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1106 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski