Amino acid dipepetide frequency for Verticillium alfalfae (strain VaMs.102 / ATCC MYA-4576 / FGSC 10136) (Verticillium wilt of alfalfa) (Verticillium albo-atrum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.592AlaAla: 11.592 ± 0.077
1.232AlaCys: 1.232 ± 0.02
4.96AlaAsp: 4.96 ± 0.037
5.533AlaGlu: 5.533 ± 0.038
3.276AlaPhe: 3.276 ± 0.028
6.801AlaGly: 6.801 ± 0.043
2.081AlaHis: 2.081 ± 0.023
4.135AlaIle: 4.135 ± 0.032
4.154AlaLys: 4.154 ± 0.039
8.266AlaLeu: 8.266 ± 0.048
2.197AlaMet: 2.197 ± 0.022
3.042AlaAsn: 3.042 ± 0.027
5.882AlaPro: 5.882 ± 0.053
3.738AlaGln: 3.738 ± 0.033
5.957AlaArg: 5.957 ± 0.045
8.021AlaSer: 8.021 ± 0.048
5.799AlaThr: 5.799 ± 0.042
6.119AlaVal: 6.119 ± 0.044
1.335AlaTrp: 1.335 ± 0.02
2.194AlaTyr: 2.194 ± 0.025
0.0AlaXaa: 0.0 ± 0.0
Cys
1.036CysAla: 1.036 ± 0.016
0.283CysCys: 0.283 ± 0.011
0.682CysAsp: 0.682 ± 0.015
0.593CysGlu: 0.593 ± 0.014
0.517CysPhe: 0.517 ± 0.012
0.973CysGly: 0.973 ± 0.02
0.371CysHis: 0.371 ± 0.01
0.656CysIle: 0.656 ± 0.014
0.476CysLys: 0.476 ± 0.013
1.238CysLeu: 1.238 ± 0.015
0.278CysMet: 0.278 ± 0.008
0.431CysAsn: 0.431 ± 0.01
0.735CysPro: 0.735 ± 0.016
0.453CysGln: 0.453 ± 0.011
0.916CysArg: 0.916 ± 0.015
0.943CysSer: 0.943 ± 0.016
0.709CysThr: 0.709 ± 0.016
0.803CysVal: 0.803 ± 0.018
0.203CysTrp: 0.203 ± 0.007
0.332CysTyr: 0.332 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
5.564AspAla: 5.564 ± 0.037
0.641AspCys: 0.641 ± 0.014
4.831AspAsp: 4.831 ± 0.051
4.586AspGlu: 4.586 ± 0.038
2.188AspPhe: 2.188 ± 0.023
4.519AspGly: 4.519 ± 0.039
1.283AspHis: 1.283 ± 0.017
2.737AspIle: 2.737 ± 0.028
2.388AspLys: 2.388 ± 0.025
4.989AspLeu: 4.989 ± 0.036
1.335AspMet: 1.335 ± 0.017
1.831AspAsn: 1.831 ± 0.022
3.29AspPro: 3.29 ± 0.028
1.859AspGln: 1.859 ± 0.021
3.169AspArg: 3.169 ± 0.032
3.889AspSer: 3.889 ± 0.038
2.901AspThr: 2.901 ± 0.028
3.928AspVal: 3.928 ± 0.028
0.898AspTrp: 0.898 ± 0.014
1.481AspTyr: 1.481 ± 0.02
0.0AspXaa: 0.0 ± 0.0
Glu
5.954GluAla: 5.954 ± 0.042
0.597GluCys: 0.597 ± 0.013
4.134GluAsp: 4.134 ± 0.04
4.934GluGlu: 4.934 ± 0.054
1.764GluPhe: 1.764 ± 0.022
3.867GluGly: 3.867 ± 0.03
1.358GluHis: 1.358 ± 0.019
2.586GluIle: 2.586 ± 0.027
3.256GluLys: 3.256 ± 0.031
4.953GluLeu: 4.953 ± 0.042
1.377GluMet: 1.377 ± 0.019
1.947GluAsn: 1.947 ± 0.021
2.969GluPro: 2.969 ± 0.048
2.322GluGln: 2.322 ± 0.029
3.854GluArg: 3.854 ± 0.035
3.9GluSer: 3.9 ± 0.035
3.47GluThr: 3.47 ± 0.029
3.548GluVal: 3.548 ± 0.03
0.812GluTrp: 0.812 ± 0.017
1.475GluTyr: 1.475 ± 0.018
0.0GluXaa: 0.0 ± 0.0
Phe
3.236PheAla: 3.236 ± 0.028
0.552PheCys: 0.552 ± 0.011
2.32PheAsp: 2.32 ± 0.023
2.078PheGlu: 2.078 ± 0.021
1.575PhePhe: 1.575 ± 0.024
2.871PheGly: 2.871 ± 0.035
0.855PheHis: 0.855 ± 0.016
1.632PheIle: 1.632 ± 0.022
1.371PheLys: 1.371 ± 0.018
3.25PheLeu: 3.25 ± 0.029
0.761PheMet: 0.761 ± 0.014
1.334PheAsn: 1.334 ± 0.017
1.864PhePro: 1.864 ± 0.022
1.285PheGln: 1.285 ± 0.018
1.942PheArg: 1.942 ± 0.022
2.726PheSer: 2.726 ± 0.029
2.02PheThr: 2.02 ± 0.023
2.395PheVal: 2.395 ± 0.022
0.644PheTrp: 0.644 ± 0.013
0.971PheTyr: 0.971 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
6.242GlyAla: 6.242 ± 0.045
0.926GlyCys: 0.926 ± 0.014
3.946GlyAsp: 3.946 ± 0.031
3.654GlyGlu: 3.654 ± 0.029
2.792GlyPhe: 2.792 ± 0.029
6.562GlyGly: 6.562 ± 0.069
1.877GlyHis: 1.877 ± 0.021
3.327GlyIle: 3.327 ± 0.03
3.287GlyLys: 3.287 ± 0.031
6.231GlyLeu: 6.231 ± 0.042
1.629GlyMet: 1.629 ± 0.021
2.523GlyAsn: 2.523 ± 0.031
3.759GlyPro: 3.759 ± 0.037
2.787GlyGln: 2.787 ± 0.036
4.8GlyArg: 4.8 ± 0.037
5.791GlySer: 5.791 ± 0.043
4.126GlyThr: 4.126 ± 0.035
4.563GlyVal: 4.563 ± 0.039
1.191GlyTrp: 1.191 ± 0.019
1.985GlyTyr: 1.985 ± 0.023
0.0GlyXaa: 0.0 ± 0.0
His
2.165HisAla: 2.165 ± 0.022
0.35HisCys: 0.35 ± 0.01
1.452HisAsp: 1.452 ± 0.02
1.361HisGlu: 1.361 ± 0.016
0.891HisPhe: 0.891 ± 0.016
1.916HisGly: 1.916 ± 0.025
0.911HisHis: 0.911 ± 0.019
1.118HisIle: 1.118 ± 0.018
0.863HisLys: 0.863 ± 0.017
2.22HisLeu: 2.22 ± 0.023
0.53HisMet: 0.53 ± 0.011
0.796HisAsn: 0.796 ± 0.015
1.655HisPro: 1.655 ± 0.024
1.071HisGln: 1.071 ± 0.015
1.695HisArg: 1.695 ± 0.021
1.716HisSer: 1.716 ± 0.022
1.227HisThr: 1.227 ± 0.016
1.597HisVal: 1.597 ± 0.02
0.345HisTrp: 0.345 ± 0.009
0.643HisTyr: 0.643 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
4.057IleAla: 4.057 ± 0.035
0.674IleCys: 0.674 ± 0.013
2.719IleAsp: 2.719 ± 0.026
2.619IleGlu: 2.619 ± 0.03
1.772IlePhe: 1.772 ± 0.023
2.987IleGly: 2.987 ± 0.029
1.093IleHis: 1.093 ± 0.015
2.249IleIle: 2.249 ± 0.023
1.934IleLys: 1.934 ± 0.024
4.071IleLeu: 4.071 ± 0.036
1.001IleMet: 1.001 ± 0.016
1.595IleAsn: 1.595 ± 0.018
2.645IlePro: 2.645 ± 0.027
1.644IleGln: 1.644 ± 0.02
2.634IleArg: 2.634 ± 0.024
3.314IleSer: 3.314 ± 0.033
2.573IleThr: 2.573 ± 0.024
3.057IleVal: 3.057 ± 0.029
0.683IleTrp: 0.683 ± 0.012
1.179IleTyr: 1.179 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
4.387LysAla: 4.387 ± 0.042
0.463LysCys: 0.463 ± 0.013
2.585LysAsp: 2.585 ± 0.03
2.893LysGlu: 2.893 ± 0.035
1.332LysPhe: 1.332 ± 0.019
2.896LysGly: 2.896 ± 0.03
1.046LysHis: 1.046 ± 0.016
1.968LysIle: 1.968 ± 0.023
3.151LysLys: 3.151 ± 0.042
3.705LysLeu: 3.705 ± 0.032
0.938LysMet: 0.938 ± 0.015
1.562LysAsn: 1.562 ± 0.021
2.651LysPro: 2.651 ± 0.031
1.688LysGln: 1.688 ± 0.02
3.186LysArg: 3.186 ± 0.03
3.127LysSer: 3.127 ± 0.034
2.852LysThr: 2.852 ± 0.023
2.65LysVal: 2.65 ± 0.03
0.62LysTrp: 0.62 ± 0.012
1.175LysTyr: 1.175 ± 0.018
0.0LysXaa: 0.0 ± 0.0
Leu
8.481LeuAla: 8.481 ± 0.052
1.167LeuCys: 1.167 ± 0.016
5.122LeuAsp: 5.122 ± 0.038
5.174LeuGlu: 5.174 ± 0.044
3.158LeuPhe: 3.158 ± 0.035
5.985LeuGly: 5.985 ± 0.037
2.187LeuHis: 2.187 ± 0.023
3.555LeuIle: 3.555 ± 0.031
3.771LeuLys: 3.771 ± 0.035
8.047LeuLeu: 8.047 ± 0.059
1.784LeuMet: 1.784 ± 0.02
2.87LeuAsn: 2.87 ± 0.026
5.544LeuPro: 5.544 ± 0.045
3.63LeuGln: 3.63 ± 0.037
5.966LeuArg: 5.966 ± 0.042
6.822LeuSer: 6.822 ± 0.045
4.853LeuThr: 4.853 ± 0.035
5.472LeuVal: 5.472 ± 0.041
1.176LeuTrp: 1.176 ± 0.014
2.116LeuTyr: 2.116 ± 0.022
0.0LeuXaa: 0.0 ± 0.0
Met
2.471MetAla: 2.471 ± 0.023
0.243MetCys: 0.243 ± 0.008
1.234MetAsp: 1.234 ± 0.017
1.174MetGlu: 1.174 ± 0.018
0.737MetPhe: 0.737 ± 0.012
1.515MetGly: 1.515 ± 0.019
0.496MetHis: 0.496 ± 0.013
0.925MetIle: 0.925 ± 0.014
0.955MetLys: 0.955 ± 0.017
1.837MetLeu: 1.837 ± 0.022
0.582MetMet: 0.582 ± 0.012
0.755MetAsn: 0.755 ± 0.016
1.366MetPro: 1.366 ± 0.022
0.821MetGln: 0.821 ± 0.017
1.356MetArg: 1.356 ± 0.018
1.859MetSer: 1.859 ± 0.021
1.405MetThr: 1.405 ± 0.018
1.334MetVal: 1.334 ± 0.019
0.273MetTrp: 0.273 ± 0.009
0.516MetTyr: 0.516 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
3.076AsnAla: 3.076 ± 0.031
0.416AsnCys: 0.416 ± 0.01
1.914AsnAsp: 1.914 ± 0.022
1.824AsnGlu: 1.824 ± 0.021
1.266AsnPhe: 1.266 ± 0.017
2.895AsnGly: 2.895 ± 0.035
0.793AsnHis: 0.793 ± 0.013
1.771AsnIle: 1.771 ± 0.02
1.44AsnLys: 1.44 ± 0.019
2.963AsnLeu: 2.963 ± 0.027
0.8AsnMet: 0.8 ± 0.013
1.357AsnAsn: 1.357 ± 0.02
2.272AsnPro: 2.272 ± 0.024
1.198AsnGln: 1.198 ± 0.018
1.835AsnArg: 1.835 ± 0.021
2.356AsnSer: 2.356 ± 0.025
2.031AsnThr: 2.031 ± 0.023
2.225AsnVal: 2.225 ± 0.022
0.516AsnTrp: 0.516 ± 0.011
0.935AsnTyr: 0.935 ± 0.016
0.0AsnXaa: 0.0 ± 0.0
Pro
6.356ProAla: 6.356 ± 0.056
0.61ProCys: 0.61 ± 0.012
3.274ProAsp: 3.274 ± 0.031
3.784ProGlu: 3.784 ± 0.038
2.003ProPhe: 2.003 ± 0.022
4.375ProGly: 4.375 ± 0.037
1.375ProHis: 1.375 ± 0.016
2.322ProIle: 2.322 ± 0.024
2.532ProLys: 2.532 ± 0.028
4.869ProLeu: 4.869 ± 0.036
1.14ProMet: 1.14 ± 0.017
2.014ProAsn: 2.014 ± 0.024
5.486ProPro: 5.486 ± 0.072
2.538ProGln: 2.538 ± 0.036
3.992ProArg: 3.992 ± 0.036
6.053ProSer: 6.053 ± 0.056
4.086ProThr: 4.086 ± 0.036
3.845ProVal: 3.845 ± 0.033
0.795ProTrp: 0.795 ± 0.012
1.406ProTyr: 1.406 ± 0.02
0.0ProXaa: 0.0 ± 0.0
Gln
3.8GlnAla: 3.8 ± 0.037
0.454GlnCys: 0.454 ± 0.011
2.098GlnAsp: 2.098 ± 0.022
2.215GlnGlu: 2.215 ± 0.029
1.166GlnPhe: 1.166 ± 0.014
2.634GlnGly: 2.634 ± 0.029
1.169GlnHis: 1.169 ± 0.02
1.669GlnIle: 1.669 ± 0.019
1.769GlnLys: 1.769 ± 0.024
3.293GlnLeu: 3.293 ± 0.033
0.872GlnMet: 0.872 ± 0.018
1.367GlnAsn: 1.367 ± 0.021
2.664GlnPro: 2.664 ± 0.035
2.85GlnGln: 2.85 ± 0.065
2.758GlnArg: 2.758 ± 0.026
2.908GlnSer: 2.908 ± 0.032
2.332GlnThr: 2.332 ± 0.024
2.219GlnVal: 2.219 ± 0.022
0.565GlnTrp: 0.565 ± 0.011
1.088GlnTyr: 1.088 ± 0.016
0.0GlnXaa: 0.0 ± 0.0
Arg
5.652ArgAla: 5.652 ± 0.042
0.847ArgCys: 0.847 ± 0.015
3.638ArgAsp: 3.638 ± 0.037
3.771ArgGlu: 3.771 ± 0.035
2.137ArgPhe: 2.137 ± 0.023
4.228ArgGly: 4.228 ± 0.039
1.874ArgHis: 1.874 ± 0.023
2.739ArgIle: 2.739 ± 0.025
3.249ArgLys: 3.249 ± 0.033
5.628ArgLeu: 5.628 ± 0.042
1.404ArgMet: 1.404 ± 0.019
2.146ArgAsn: 2.146 ± 0.024
4.159ArgPro: 4.159 ± 0.038
2.925ArgGln: 2.925 ± 0.03
6.063ArgArg: 6.063 ± 0.049
4.97ArgSer: 4.97 ± 0.043
3.545ArgThr: 3.545 ± 0.03
3.534ArgVal: 3.534 ± 0.027
1.024ArgTrp: 1.024 ± 0.014
1.595ArgTyr: 1.595 ± 0.018
0.0ArgXaa: 0.0 ± 0.0
Ser
7.112SerAla: 7.112 ± 0.047
0.919SerCys: 0.919 ± 0.015
4.09SerAsp: 4.09 ± 0.032
3.772SerGlu: 3.772 ± 0.036
2.885SerPhe: 2.885 ± 0.023
5.575SerGly: 5.575 ± 0.039
1.911SerHis: 1.911 ± 0.022
3.56SerIle: 3.56 ± 0.027
3.318SerLys: 3.318 ± 0.034
6.835SerLeu: 6.835 ± 0.041
1.725SerMet: 1.725 ± 0.021
2.657SerAsn: 2.657 ± 0.028
5.511SerPro: 5.511 ± 0.049
3.076SerGln: 3.076 ± 0.031
5.268SerArg: 5.268 ± 0.043
8.448SerSer: 8.448 ± 0.066
5.345SerThr: 5.345 ± 0.039
4.513SerVal: 4.513 ± 0.032
1.136SerTrp: 1.136 ± 0.017
1.859SerTyr: 1.859 ± 0.021
0.0SerXaa: 0.0 ± 0.0
Thr
5.806ThrAla: 5.806 ± 0.038
0.809ThrCys: 0.809 ± 0.02
2.899ThrAsp: 2.899 ± 0.029
2.966ThrGlu: 2.966 ± 0.023
2.126ThrPhe: 2.126 ± 0.023
4.251ThrGly: 4.251 ± 0.038
1.291ThrHis: 1.291 ± 0.018
2.888ThrIle: 2.888 ± 0.025
2.501ThrLys: 2.501 ± 0.025
5.111ThrLeu: 5.111 ± 0.039
1.232ThrMet: 1.232 ± 0.014
1.987ThrAsn: 1.987 ± 0.025
4.527ThrPro: 4.527 ± 0.036
2.097ThrGln: 2.097 ± 0.024
3.45ThrArg: 3.45 ± 0.029
5.22ThrSer: 5.22 ± 0.04
4.413ThrThr: 4.413 ± 0.045
3.739ThrVal: 3.739 ± 0.032
0.903ThrTrp: 0.903 ± 0.015
1.468ThrTyr: 1.468 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
5.935ValAla: 5.935 ± 0.043
0.868ValCys: 0.868 ± 0.018
3.886ValAsp: 3.886 ± 0.029
3.9ValGlu: 3.9 ± 0.033
2.468ValPhe: 2.468 ± 0.03
4.18ValGly: 4.18 ± 0.039
1.435ValHis: 1.435 ± 0.019
2.777ValIle: 2.777 ± 0.025
2.766ValLys: 2.766 ± 0.027
5.671ValLeu: 5.671 ± 0.044
1.332ValMet: 1.332 ± 0.017
2.106ValAsn: 2.106 ± 0.022
3.822ValPro: 3.822 ± 0.033
2.328ValGln: 2.328 ± 0.024
3.707ValArg: 3.707 ± 0.035
4.595ValSer: 4.595 ± 0.032
3.62ValThr: 3.62 ± 0.027
4.489ValVal: 4.489 ± 0.035
0.905ValTrp: 0.905 ± 0.015
1.639ValTyr: 1.639 ± 0.018
0.0ValXaa: 0.0 ± 0.0
Trp
1.244TrpAla: 1.244 ± 0.019
0.206TrpCys: 0.206 ± 0.007
0.908TrpAsp: 0.908 ± 0.014
0.798TrpGlu: 0.798 ± 0.014
0.553TrpPhe: 0.553 ± 0.011
0.977TrpGly: 0.977 ± 0.018
0.4TrpHis: 0.4 ± 0.01
0.693TrpIle: 0.693 ± 0.013
0.724TrpLys: 0.724 ± 0.013
1.352TrpLeu: 1.352 ± 0.016
0.367TrpMet: 0.367 ± 0.009
0.583TrpAsn: 0.583 ± 0.013
0.701TrpPro: 0.701 ± 0.012
0.606TrpGln: 0.606 ± 0.012
1.031TrpArg: 1.031 ± 0.017
1.078TrpSer: 1.078 ± 0.017
0.948TrpThr: 0.948 ± 0.015
0.883TrpVal: 0.883 ± 0.014
0.282TrpTrp: 0.282 ± 0.009
0.402TrpTyr: 0.402 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.151TyrAla: 2.151 ± 0.021
0.37TyrCys: 0.37 ± 0.01
1.613TyrAsp: 1.613 ± 0.021
1.451TyrGlu: 1.451 ± 0.019
1.078TyrPhe: 1.078 ± 0.015
1.993TyrGly: 1.993 ± 0.028
0.716TyrHis: 0.716 ± 0.014
1.192TyrIle: 1.192 ± 0.017
0.967TyrLys: 0.967 ± 0.017
2.351TyrLeu: 2.351 ± 0.024
0.572TyrMet: 0.572 ± 0.012
0.979TyrAsn: 0.979 ± 0.015
1.353TyrPro: 1.353 ± 0.02
0.973TyrGln: 0.973 ± 0.014
1.55TyrArg: 1.55 ± 0.021
1.778TyrSer: 1.778 ± 0.021
1.427TyrThr: 1.427 ± 0.016
1.514TyrVal: 1.514 ± 0.017
0.431TyrTrp: 0.431 ± 0.01
0.788TyrTyr: 0.788 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10233 proteins (4470746 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski