Amino acid dipepetide frequency for Paraurantiacibacter namhicola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.862AlaAla: 17.862 ± 0.246	1.182AlaCys: 1.182 ± 0.042	7.633AlaAsp: 7.633 ± 0.11	8.371AlaGlu: 8.371 ± 0.138	4.264AlaPhe: 4.264 ± 0.074	11.344AlaGly: 11.344 ± 0.134	2.169AlaHis: 2.169 ± 0.06	6.69AlaIle: 6.69 ± 0.123	4.25AlaLys: 4.25 ± 0.093	13.638AlaLeu: 13.638 ± 0.168	4.243AlaMet: 4.243 ± 0.081	3.155AlaAsn: 3.155 ± 0.066	5.799AlaPro: 5.799 ± 0.113	4.682AlaGln: 4.682 ± 0.084	9.076AlaArg: 9.076 ± 0.129	6.632AlaSer: 6.632 ± 0.087	5.567AlaThr: 5.567 ± 0.089	7.911AlaVal: 7.911 ± 0.114	1.612AlaTrp: 1.612 ± 0.048	2.5AlaTyr: 2.5 ± 0.058	0.0AlaXaa: 0.0 ± 0.0
Cys	1.027CysAla: 1.027 ± 0.036	0.086CysCys: 0.086 ± 0.011	0.622CysAsp: 0.622 ± 0.032	0.562CysGlu: 0.562 ± 0.025	0.268CysPhe: 0.268 ± 0.02	0.915CysGly: 0.915 ± 0.043	0.192CysHis: 0.192 ± 0.019	0.359CysIle: 0.359 ± 0.024	0.174CysLys: 0.174 ± 0.014	0.69CysLeu: 0.69 ± 0.03	0.165CysMet: 0.165 ± 0.013	0.238CysAsn: 0.238 ± 0.018	0.436CysPro: 0.436 ± 0.025	0.214CysGln: 0.214 ± 0.017	0.581CysArg: 0.581 ± 0.029	0.476CysSer: 0.476 ± 0.026	0.432CysThr: 0.432 ± 0.028	0.626CysVal: 0.626 ± 0.033	0.095CysTrp: 0.095 ± 0.012	0.174CysTyr: 0.174 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	8.091AspAla: 8.091 ± 0.096	0.567AspCys: 0.567 ± 0.029	3.579AspAsp: 3.579 ± 0.082	4.084AspGlu: 4.084 ± 0.088	2.459AspPhe: 2.459 ± 0.061	6.541AspGly: 6.541 ± 0.115	1.241AspHis: 1.241 ± 0.048	3.003AspIle: 3.003 ± 0.066	1.836AspLys: 1.836 ± 0.05	5.549AspLeu: 5.549 ± 0.1	1.726AspMet: 1.726 ± 0.05	1.605AspAsn: 1.605 ± 0.046	3.729AspPro: 3.729 ± 0.066	1.685AspGln: 1.685 ± 0.044	4.606AspArg: 4.606 ± 0.077	2.546AspSer: 2.546 ± 0.055	3.057AspThr: 3.057 ± 0.065	4.111AspVal: 4.111 ± 0.065	1.181AspTrp: 1.181 ± 0.04	1.67AspTyr: 1.67 ± 0.044	0.0AspXaa: 0.0 ± 0.0
Glu	8.509GluAla: 8.509 ± 0.125	0.424GluCys: 0.424 ± 0.023	3.917GluAsp: 3.917 ± 0.081	4.303GluGlu: 4.303 ± 0.102	1.915GluPhe: 1.915 ± 0.05	5.521GluGly: 5.521 ± 0.093	1.217GluHis: 1.217 ± 0.039	3.012GluIle: 3.012 ± 0.062	2.429GluLys: 2.429 ± 0.061	5.68GluLeu: 5.68 ± 0.082	1.714GluMet: 1.714 ± 0.048	1.685GluAsn: 1.685 ± 0.045	2.921GluPro: 2.921 ± 0.073	2.361GluGln: 2.361 ± 0.058	5.136GluArg: 5.136 ± 0.087	2.549GluSer: 2.549 ± 0.052	3.496GluThr: 3.496 ± 0.07	4.071GluVal: 4.071 ± 0.073	0.983GluTrp: 0.983 ± 0.034	1.233GluTyr: 1.233 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	4.977PheAla: 4.977 ± 0.074	0.352PheCys: 0.352 ± 0.023	2.797PheAsp: 2.797 ± 0.064	2.236PheGlu: 2.236 ± 0.055	1.382PhePhe: 1.382 ± 0.047	3.762PheGly: 3.762 ± 0.078	0.635PheHis: 0.635 ± 0.026	1.567PheIle: 1.567 ± 0.049	0.825PheLys: 0.825 ± 0.034	3.176PheLeu: 3.176 ± 0.067	0.79PheMet: 0.79 ± 0.034	0.946PheAsn: 0.946 ± 0.037	1.58PhePro: 1.58 ± 0.049	0.913PheGln: 0.913 ± 0.034	2.169PheArg: 2.169 ± 0.047	2.039PheSer: 2.039 ± 0.057	2.092PheThr: 2.092 ± 0.054	2.669PheVal: 2.669 ± 0.052	0.552PheTrp: 0.552 ± 0.028	0.963PheTyr: 0.963 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	9.728GlyAla: 9.728 ± 0.122	0.844GlyCys: 0.844 ± 0.035	5.367GlyAsp: 5.367 ± 0.09	6.232GlyGlu: 6.232 ± 0.094	3.623GlyPhe: 3.623 ± 0.066	8.421GlyGly: 8.421 ± 0.152	1.815GlyHis: 1.815 ± 0.054	4.463GlyIle: 4.463 ± 0.08	3.59GlyLys: 3.59 ± 0.08	8.624GlyLeu: 8.624 ± 0.126	2.712GlyMet: 2.712 ± 0.065	2.475GlyAsn: 2.475 ± 0.07	3.824GlyPro: 3.824 ± 0.069	3.067GlyGln: 3.067 ± 0.07	6.175GlyArg: 6.175 ± 0.091	5.171GlySer: 5.171 ± 0.085	5.036GlyThr: 5.036 ± 0.095	6.125GlyVal: 6.125 ± 0.093	1.706GlyTrp: 1.706 ± 0.051	2.381GlyTyr: 2.381 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.247HisAla: 2.247 ± 0.06	0.248HisCys: 0.248 ± 0.02	1.207HisAsp: 1.207 ± 0.042	1.085HisGlu: 1.085 ± 0.036	0.863HisPhe: 0.863 ± 0.033	1.954HisGly: 1.954 ± 0.053	0.52HisHis: 0.52 ± 0.032	0.837HisIle: 0.837 ± 0.039	0.499HisLys: 0.499 ± 0.026	1.689HisLeu: 1.689 ± 0.05	0.419HisMet: 0.419 ± 0.021	0.439HisAsn: 0.439 ± 0.028	1.216HisPro: 1.216 ± 0.04	0.487HisGln: 0.487 ± 0.024	1.385HisArg: 1.385 ± 0.044	0.898HisSer: 0.898 ± 0.037	0.77HisThr: 0.77 ± 0.028	1.391HisVal: 1.391 ± 0.046	0.318HisTrp: 0.318 ± 0.019	0.499HisTyr: 0.499 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	7.54IleAla: 7.54 ± 0.117	0.421IleCys: 0.421 ± 0.023	3.277IleAsp: 3.277 ± 0.069	3.299IleGlu: 3.299 ± 0.068	1.602IlePhe: 1.602 ± 0.044	4.995IleGly: 4.995 ± 0.081	0.817IleHis: 0.817 ± 0.037	1.952IleIle: 1.952 ± 0.053	1.072IleLys: 1.072 ± 0.043	3.694IleLeu: 3.694 ± 0.063	0.954IleMet: 0.954 ± 0.034	1.174IleAsn: 1.174 ± 0.039	2.301IlePro: 2.301 ± 0.05	0.996IleGln: 0.996 ± 0.038	2.956IleArg: 2.956 ± 0.056	2.495IleSer: 2.495 ± 0.06	2.391IleThr: 2.391 ± 0.058	3.786IleVal: 3.786 ± 0.062	0.551IleTrp: 0.551 ± 0.027	1.008IleTyr: 1.008 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.938LysAla: 3.938 ± 0.087	0.194LysCys: 0.194 ± 0.016	1.819LysAsp: 1.819 ± 0.048	1.475LysGlu: 1.475 ± 0.047	0.915LysPhe: 0.915 ± 0.035	2.583LysGly: 2.583 ± 0.074	0.572LysHis: 0.572 ± 0.03	1.391LysIle: 1.391 ± 0.044	1.367LysLys: 1.367 ± 0.066	3.269LysLeu: 3.269 ± 0.076	0.801LysMet: 0.801 ± 0.035	0.704LysAsn: 0.704 ± 0.032	2.01LysPro: 2.01 ± 0.057	1.042LysGln: 1.042 ± 0.037	2.425LysArg: 2.425 ± 0.062	1.667LysSer: 1.667 ± 0.054	1.706LysThr: 1.706 ± 0.042	2.156LysVal: 2.156 ± 0.066	0.429LysTrp: 0.429 ± 0.023	0.676LysTyr: 0.676 ± 0.029	0.0LysXaa: 0.0 ± 0.0
Leu	14.176LeuAla: 14.176 ± 0.183	0.79LeuCys: 0.79 ± 0.034	6.135LeuAsp: 6.135 ± 0.102	5.849LeuGlu: 5.849 ± 0.092	3.52LeuPhe: 3.52 ± 0.081	8.47LeuGly: 8.47 ± 0.1	1.719LeuHis: 1.719 ± 0.048	3.822LeuIle: 3.822 ± 0.07	2.838LeuLys: 2.838 ± 0.069	9.562LeuLeu: 9.562 ± 0.146	2.153LeuMet: 2.153 ± 0.054	2.019LeuAsn: 2.019 ± 0.052	5.472LeuPro: 5.472 ± 0.084	2.735LeuGln: 2.735 ± 0.057	6.261LeuArg: 6.261 ± 0.106	5.779LeuSer: 5.779 ± 0.086	5.211LeuThr: 5.211 ± 0.079	7.704LeuVal: 7.704 ± 0.102	1.17LeuTrp: 1.17 ± 0.042	1.892LeuTyr: 1.892 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	3.707MetAla: 3.707 ± 0.074	0.15MetCys: 0.15 ± 0.014	1.476MetAsp: 1.476 ± 0.043	1.458MetGlu: 1.458 ± 0.046	0.7MetPhe: 0.7 ± 0.03	2.096MetGly: 2.096 ± 0.056	0.515MetHis: 0.515 ± 0.026	1.148MetIle: 1.148 ± 0.042	1.015MetLys: 1.015 ± 0.038	2.779MetLeu: 2.779 ± 0.068	0.686MetMet: 0.686 ± 0.03	0.71MetAsn: 0.71 ± 0.028	1.579MetPro: 1.579 ± 0.046	0.978MetGln: 0.978 ± 0.036	1.922MetArg: 1.922 ± 0.044	1.471MetSer: 1.471 ± 0.041	1.605MetThr: 1.605 ± 0.043	1.778MetVal: 1.778 ± 0.047	0.272MetTrp: 0.272 ± 0.021	0.319MetTyr: 0.319 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.163AsnAla: 3.163 ± 0.069	0.3AsnCys: 0.3 ± 0.02	1.292AsnAsp: 1.292 ± 0.04	1.178AsnGlu: 1.178 ± 0.042	1.018AsnPhe: 1.018 ± 0.035	2.33AsnGly: 2.33 ± 0.069	0.464AsnHis: 0.464 ± 0.028	1.273AsnIle: 1.273 ± 0.041	0.601AsnLys: 0.601 ± 0.03	2.451AsnLeu: 2.451 ± 0.058	0.577AsnMet: 0.577 ± 0.028	0.593AsnAsn: 0.593 ± 0.027	1.82AsnPro: 1.82 ± 0.052	0.705AsnGln: 0.705 ± 0.029	1.728AsnArg: 1.728 ± 0.046	1.288AsnSer: 1.288 ± 0.042	1.233AsnThr: 1.233 ± 0.039	1.857AsnVal: 1.857 ± 0.057	0.411AsnTrp: 0.411 ± 0.023	0.667AsnTyr: 0.667 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	6.779ProAla: 6.779 ± 0.131	0.309ProCys: 0.309 ± 0.022	4.144ProAsp: 4.144 ± 0.07	4.051ProGlu: 4.051 ± 0.071	1.913ProPhe: 1.913 ± 0.049	4.721ProGly: 4.721 ± 0.08	1.012ProHis: 1.012 ± 0.034	2.198ProIle: 2.198 ± 0.051	1.498ProLys: 1.498 ± 0.05	4.767ProLeu: 4.767 ± 0.087	1.207ProMet: 1.207 ± 0.035	1.216ProAsn: 1.216 ± 0.041	2.465ProPro: 2.465 ± 0.1	1.997ProGln: 1.997 ± 0.051	2.824ProArg: 2.824 ± 0.068	2.487ProSer: 2.487 ± 0.058	2.26ProThr: 2.26 ± 0.067	4.192ProVal: 4.192 ± 0.074	0.648ProTrp: 0.648 ± 0.029	1.134ProTyr: 1.134 ± 0.041	0.0ProXaa: 0.0 ± 0.0
Gln	4.293GlnAla: 4.293 ± 0.094	0.224GlnCys: 0.224 ± 0.017	2.0GlnAsp: 2.0 ± 0.048	1.67GlnGlu: 1.67 ± 0.051	1.181GlnPhe: 1.181 ± 0.033	2.614GlnGly: 2.614 ± 0.065	0.62GlnHis: 0.62 ± 0.029	1.512GlnIle: 1.512 ± 0.045	0.871GlnLys: 0.871 ± 0.037	3.241GlnLeu: 3.241 ± 0.066	0.868GlnMet: 0.868 ± 0.032	0.741GlnAsn: 0.741 ± 0.033	1.913GlnPro: 1.913 ± 0.057	1.266GlnGln: 1.266 ± 0.042	2.481GlnArg: 2.481 ± 0.059	1.694GlnSer: 1.694 ± 0.042	1.511GlnThr: 1.511 ± 0.047	2.529GlnVal: 2.529 ± 0.056	0.439GlnTrp: 0.439 ± 0.027	0.66GlnTyr: 0.66 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	7.839ArgAla: 7.839 ± 0.111	0.493ArgCys: 0.493 ± 0.021	4.239ArgAsp: 4.239 ± 0.076	4.777ArgGlu: 4.777 ± 0.073	2.962ArgPhe: 2.962 ± 0.058	5.144ArgGly: 5.144 ± 0.095	1.525ArgHis: 1.525 ± 0.047	3.771ArgIle: 3.771 ± 0.066	2.395ArgLys: 2.395 ± 0.065	7.204ArgLeu: 7.204 ± 0.109	2.087ArgMet: 2.087 ± 0.054	1.774ArgAsn: 1.774 ± 0.047	3.264ArgPro: 3.264 ± 0.073	2.445ArgGln: 2.445 ± 0.057	4.989ArgArg: 4.989 ± 0.106	3.516ArgSer: 3.516 ± 0.072	3.173ArgThr: 3.173 ± 0.064	4.661ArgVal: 4.661 ± 0.087	1.097ArgTrp: 1.097 ± 0.04	1.695ArgTyr: 1.695 ± 0.059	0.0ArgXaa: 0.0 ± 0.0
Ser	6.241SerAla: 6.241 ± 0.088	0.433SerCys: 0.433 ± 0.03	3.264SerAsp: 3.264 ± 0.072	3.062SerGlu: 3.062 ± 0.066	2.084SerPhe: 2.084 ± 0.051	5.806SerGly: 5.806 ± 0.101	0.944SerHis: 0.944 ± 0.032	2.475SerIle: 2.475 ± 0.062	1.44SerLys: 1.44 ± 0.047	5.071SerLeu: 5.071 ± 0.076	1.318SerMet: 1.318 ± 0.041	1.365SerAsn: 1.365 ± 0.043	2.663SerPro: 2.663 ± 0.067	1.637SerGln: 1.637 ± 0.043	3.459SerArg: 3.459 ± 0.069	2.695SerSer: 2.695 ± 0.067	2.49SerThr: 2.49 ± 0.055	3.58SerVal: 3.58 ± 0.067	0.797SerTrp: 0.797 ± 0.032	1.293SerTyr: 1.293 ± 0.045	0.0SerXaa: 0.0 ± 0.0
Thr	5.884ThrAla: 5.884 ± 0.097	0.427ThrCys: 0.427 ± 0.025	3.063ThrAsp: 3.063 ± 0.066	2.536ThrGlu: 2.536 ± 0.052	1.899ThrPhe: 1.899 ± 0.052	5.418ThrGly: 5.418 ± 0.076	0.89ThrHis: 0.89 ± 0.04	2.695ThrIle: 2.695 ± 0.062	1.366ThrLys: 1.366 ± 0.041	5.272ThrLeu: 5.272 ± 0.086	1.284ThrMet: 1.284 ± 0.043	1.286ThrAsn: 1.286 ± 0.041	3.279ThrPro: 3.279 ± 0.069	1.646ThrGln: 1.646 ± 0.051	3.204ThrArg: 3.204 ± 0.071	2.616ThrSer: 2.616 ± 0.062	2.496ThrThr: 2.496 ± 0.058	3.902ThrVal: 3.902 ± 0.073	0.592ThrTrp: 0.592 ± 0.028	1.246ThrTyr: 1.246 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	8.513ValAla: 8.513 ± 0.101	0.533ValCys: 0.533 ± 0.026	4.631ValAsp: 4.631 ± 0.08	4.817ValGlu: 4.817 ± 0.083	2.379ValPhe: 2.379 ± 0.05	5.598ValGly: 5.598 ± 0.093	1.271ValHis: 1.271 ± 0.034	3.594ValIle: 3.594 ± 0.072	2.054ValLys: 2.054 ± 0.059	7.013ValLeu: 7.013 ± 0.113	1.843ValMet: 1.843 ± 0.051	1.801ValAsn: 1.801 ± 0.049	3.754ValPro: 3.754 ± 0.067	2.071ValGln: 2.071 ± 0.055	4.567ValArg: 4.567 ± 0.075	3.947ValSer: 3.947 ± 0.071	4.626ValThr: 4.626 ± 0.081	5.089ValVal: 5.089 ± 0.097	0.924ValTrp: 0.924 ± 0.041	1.344ValTyr: 1.344 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.373TrpAla: 1.373 ± 0.049	0.124TrpCys: 0.124 ± 0.012	0.804TrpAsp: 0.804 ± 0.031	0.66TrpGlu: 0.66 ± 0.029	0.606TrpPhe: 0.606 ± 0.027	0.955TrpGly: 0.955 ± 0.039	0.335TrpHis: 0.335 ± 0.024	0.647TrpIle: 0.647 ± 0.031	0.457TrpLys: 0.457 ± 0.019	1.862TrpLeu: 1.862 ± 0.053	0.388TrpMet: 0.388 ± 0.021	0.429TrpAsn: 0.429 ± 0.026	0.786TrpPro: 0.786 ± 0.034	0.735TrpGln: 0.735 ± 0.031	1.246TrpArg: 1.246 ± 0.041	0.871TrpSer: 0.871 ± 0.035	0.757TrpThr: 0.757 ± 0.035	0.8TrpVal: 0.8 ± 0.035	0.282TrpTrp: 0.282 ± 0.021	0.299TrpTyr: 0.299 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.693TyrAla: 2.693 ± 0.062	0.229TyrCys: 0.229 ± 0.016	1.601TyrAsp: 1.601 ± 0.049	1.371TyrGlu: 1.371 ± 0.049	0.87TyrPhe: 0.87 ± 0.034	2.193TyrGly: 2.193 ± 0.058	0.499TyrHis: 0.499 ± 0.029	0.87TyrIle: 0.87 ± 0.034	0.561TyrLys: 0.561 ± 0.024	2.047TyrLeu: 2.047 ± 0.048	0.426TyrMet: 0.426 ± 0.02	0.595TyrAsn: 0.595 ± 0.028	1.013TyrPro: 1.013 ± 0.037	0.666TyrGln: 0.666 ± 0.034	1.862TyrArg: 1.862 ± 0.048	1.279TyrSer: 1.279 ± 0.044	1.09TyrThr: 1.09 ± 0.038	1.432TyrVal: 1.432 ± 0.042	0.357TyrTrp: 0.357 ± 0.022	0.615TyrTyr: 0.615 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2513 proteins (798812 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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