Amino acid dipepetide frequency for Chlorobium phaeovibrioides (strain DSM 265 / 1930) (Prosthecochloris vibrioformis (strain DSM 265))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.503AlaAla: 10.503 ± 0.185
0.963AlaCys: 0.963 ± 0.054
5.011AlaAsp: 5.011 ± 0.193
6.602AlaGlu: 6.602 ± 0.151
3.623AlaPhe: 3.623 ± 0.079
8.54AlaGly: 8.54 ± 0.143
1.476AlaHis: 1.476 ± 0.048
5.67AlaIle: 5.67 ± 0.095
3.67AlaLys: 3.67 ± 0.117
10.349AlaLeu: 10.349 ± 0.172
2.802AlaMet: 2.802 ± 0.08
2.35AlaAsn: 2.35 ± 0.076
3.48AlaPro: 3.48 ± 0.081
2.14AlaGln: 2.14 ± 0.067
5.008AlaArg: 5.008 ± 0.123
5.847AlaSer: 5.847 ± 0.109
4.351AlaThr: 4.351 ± 0.178
7.069AlaVal: 7.069 ± 0.123
0.946AlaTrp: 0.946 ± 0.051
2.266AlaTyr: 2.266 ± 0.062
0.0AlaXaa: 0.0 ± 0.0
Cys
0.698CysAla: 0.698 ± 0.036
0.2CysCys: 0.2 ± 0.02
0.538CysAsp: 0.538 ± 0.036
0.476CysGlu: 0.476 ± 0.038
0.429CysPhe: 0.429 ± 0.029
1.049CysGly: 1.049 ± 0.048
0.309CysHis: 0.309 ± 0.025
0.61CysIle: 0.61 ± 0.037
0.282CysLys: 0.282 ± 0.026
0.765CysLeu: 0.765 ± 0.042
0.291CysMet: 0.291 ± 0.023
0.407CysAsn: 0.407 ± 0.028
0.657CysPro: 0.657 ± 0.045
0.286CysGln: 0.286 ± 0.025
0.847CysArg: 0.847 ± 0.038
0.83CysSer: 0.83 ± 0.043
0.516CysThr: 0.516 ± 0.029
0.548CysVal: 0.548 ± 0.032
0.094CysTrp: 0.094 ± 0.014
0.266CysTyr: 0.266 ± 0.021
0.0CysXaa: 0.0 ± 0.0
Asp
5.057AspAla: 5.057 ± 0.199
0.55AspCys: 0.55 ± 0.032
2.77AspAsp: 2.77 ± 0.185
3.712AspGlu: 3.712 ± 0.112
2.506AspPhe: 2.506 ± 0.077
4.334AspGly: 4.334 ± 0.198
0.925AspHis: 0.925 ± 0.039
3.838AspIle: 3.838 ± 0.1
1.824AspLys: 1.824 ± 0.064
4.773AspLeu: 4.773 ± 0.124
1.384AspMet: 1.384 ± 0.053
1.503AspAsn: 1.503 ± 0.07
2.426AspPro: 2.426 ± 0.082
1.165AspGln: 1.165 ± 0.052
3.413AspArg: 3.413 ± 0.074
3.377AspSer: 3.377 ± 0.119
2.816AspThr: 2.816 ± 0.158
3.31AspVal: 3.31 ± 0.122
0.614AspTrp: 0.614 ± 0.036
1.718AspTyr: 1.718 ± 0.057
0.0AspXaa: 0.0 ± 0.0
Glu
6.681GluAla: 6.681 ± 0.163
0.649GluCys: 0.649 ± 0.032
2.964GluAsp: 2.964 ± 0.084
5.405GluGlu: 5.405 ± 0.151
2.402GluPhe: 2.402 ± 0.063
5.453GluGly: 5.453 ± 0.113
1.525GluHis: 1.525 ± 0.058
4.1GluIle: 4.1 ± 0.099
4.44GluLys: 4.44 ± 0.111
7.242GluLeu: 7.242 ± 0.124
1.884GluMet: 1.884 ± 0.054
2.343GluAsn: 2.343 ± 0.057
2.448GluPro: 2.448 ± 0.08
2.397GluGln: 2.397 ± 0.086
4.287GluArg: 4.287 ± 0.128
4.09GluSer: 4.09 ± 0.091
3.49GluThr: 3.49 ± 0.082
4.364GluVal: 4.364 ± 0.105
0.632GluTrp: 0.632 ± 0.035
1.826GluTyr: 1.826 ± 0.06
0.0GluXaa: 0.0 ± 0.0
Phe
3.517PheAla: 3.517 ± 0.081
0.471PheCys: 0.471 ± 0.029
2.38PheAsp: 2.38 ± 0.063
2.347PheGlu: 2.347 ± 0.064
2.192PhePhe: 2.192 ± 0.07
3.281PheGly: 3.281 ± 0.07
0.925PheHis: 0.925 ± 0.04
2.634PheIle: 2.634 ± 0.069
1.358PheLys: 1.358 ± 0.051
4.204PheLeu: 4.204 ± 0.101
1.104PheMet: 1.104 ± 0.044
1.53PheAsn: 1.53 ± 0.056
1.805PhePro: 1.805 ± 0.065
1.14PheGln: 1.14 ± 0.041
2.676PheArg: 2.676 ± 0.07
3.84PheSer: 3.84 ± 0.08
2.453PheThr: 2.453 ± 0.082
2.787PheVal: 2.787 ± 0.073
0.503PheTrp: 0.503 ± 0.027
1.17PheTyr: 1.17 ± 0.051
0.0PheXaa: 0.0 ± 0.0
Gly
6.714GlyAla: 6.714 ± 0.153
0.985GlyCys: 0.985 ± 0.045
3.789GlyAsp: 3.789 ± 0.197
5.344GlyGlu: 5.344 ± 0.113
3.639GlyPhe: 3.639 ± 0.094
6.61GlyGly: 6.61 ± 0.16
1.651GlyHis: 1.651 ± 0.059
5.648GlyIle: 5.648 ± 0.098
4.278GlyLys: 4.278 ± 0.109
7.064GlyLeu: 7.064 ± 0.116
2.69GlyMet: 2.69 ± 0.078
2.614GlyAsn: 2.614 ± 0.104
2.231GlyPro: 2.231 ± 0.068
1.972GlyGln: 1.972 ± 0.053
4.883GlyArg: 4.883 ± 0.128
5.712GlySer: 5.712 ± 0.194
4.863GlyThr: 4.863 ± 0.258
5.593GlyVal: 5.593 ± 0.111
0.96GlyTrp: 0.96 ± 0.045
2.585GlyTyr: 2.585 ± 0.069
0.0GlyXaa: 0.0 ± 0.0
His
1.765HisAla: 1.765 ± 0.064
0.301HisCys: 0.301 ± 0.025
1.135HisAsp: 1.135 ± 0.044
1.426HisGlu: 1.426 ± 0.058
0.955HisPhe: 0.955 ± 0.043
1.56HisGly: 1.56 ± 0.05
0.577HisHis: 0.577 ± 0.033
1.232HisIle: 1.232 ± 0.049
0.768HisLys: 0.768 ± 0.037
2.13HisLeu: 2.13 ± 0.064
0.486HisMet: 0.486 ± 0.028
0.719HisAsn: 0.719 ± 0.032
1.298HisPro: 1.298 ± 0.059
0.644HisGln: 0.644 ± 0.035
1.268HisArg: 1.268 ± 0.06
1.426HisSer: 1.426 ± 0.054
1.168HisThr: 1.168 ± 0.051
1.064HisVal: 1.064 ± 0.048
0.235HisTrp: 0.235 ± 0.02
0.698HisTyr: 0.698 ± 0.033
0.0HisXaa: 0.0 ± 0.0
Ile
6.583IleAla: 6.583 ± 0.12
0.62IleCys: 0.62 ± 0.034
3.804IleAsp: 3.804 ± 0.097
4.27IleGlu: 4.27 ± 0.11
2.343IlePhe: 2.343 ± 0.069
5.013IleGly: 5.013 ± 0.109
1.202IleHis: 1.202 ± 0.048
3.739IleIle: 3.739 ± 0.094
2.387IleLys: 2.387 ± 0.08
5.568IleLeu: 5.568 ± 0.116
1.405IleMet: 1.405 ± 0.058
2.137IleAsn: 2.137 ± 0.066
2.902IlePro: 2.902 ± 0.088
1.624IleGln: 1.624 ± 0.053
3.618IleArg: 3.618 ± 0.099
4.502IleSer: 4.502 ± 0.093
3.695IleThr: 3.695 ± 0.152
4.12IleVal: 4.12 ± 0.09
0.464IleTrp: 0.464 ± 0.032
1.572IleTyr: 1.572 ± 0.047
0.0IleXaa: 0.0 ± 0.0
Lys
4.485LysAla: 4.485 ± 0.126
0.293LysCys: 0.293 ± 0.027
1.963LysAsp: 1.963 ± 0.075
3.658LysGlu: 3.658 ± 0.111
1.389LysPhe: 1.389 ± 0.052
3.742LysGly: 3.742 ± 0.092
0.903LysHis: 0.903 ± 0.044
2.945LysIle: 2.945 ± 0.088
3.518LysLys: 3.518 ± 0.11
4.046LysLeu: 4.046 ± 0.11
1.175LysMet: 1.175 ± 0.049
2.032LysAsn: 2.032 ± 0.063
1.963LysPro: 1.963 ± 0.061
1.555LysGln: 1.555 ± 0.057
2.557LysArg: 2.557 ± 0.08
2.871LysSer: 2.871 ± 0.092
2.831LysThr: 2.831 ± 0.076
3.224LysVal: 3.224 ± 0.091
0.363LysTrp: 0.363 ± 0.029
1.123LysTyr: 1.123 ± 0.046
0.0LysXaa: 0.0 ± 0.0
Leu
9.095LeuAla: 9.095 ± 0.135
0.93LeuCys: 0.93 ± 0.043
5.389LeuAsp: 5.389 ± 0.119
6.862LeuGlu: 6.862 ± 0.147
4.781LeuPhe: 4.781 ± 0.122
7.106LeuGly: 7.106 ± 0.121
2.251LeuHis: 2.251 ± 0.078
5.312LeuIle: 5.312 ± 0.108
5.4LeuLys: 5.4 ± 0.112
10.981LeuLeu: 10.981 ± 0.236
2.638LeuMet: 2.638 ± 0.087
3.505LeuAsn: 3.505 ± 0.091
4.756LeuPro: 4.756 ± 0.114
4.06LeuGln: 4.06 ± 0.098
5.985LeuArg: 5.985 ± 0.156
7.607LeuSer: 7.607 ± 0.13
5.095LeuThr: 5.095 ± 0.168
6.524LeuVal: 6.524 ± 0.121
0.941LeuTrp: 0.941 ± 0.046
2.765LeuTyr: 2.765 ± 0.074
0.0LeuXaa: 0.0 ± 0.0
Met
2.592MetAla: 2.592 ± 0.083
0.156MetCys: 0.156 ± 0.016
1.264MetAsp: 1.264 ± 0.042
1.856MetGlu: 1.856 ± 0.06
0.866MetPhe: 0.866 ± 0.038
1.829MetGly: 1.829 ± 0.06
0.662MetHis: 0.662 ± 0.032
1.486MetIle: 1.486 ± 0.053
1.942MetLys: 1.942 ± 0.063
3.076MetLeu: 3.076 ± 0.088
0.872MetMet: 0.872 ± 0.039
1.155MetAsn: 1.155 ± 0.051
1.36MetPro: 1.36 ± 0.047
1.276MetGln: 1.276 ± 0.052
1.466MetArg: 1.466 ± 0.05
1.548MetSer: 1.548 ± 0.051
1.573MetThr: 1.573 ± 0.057
1.915MetVal: 1.915 ± 0.057
0.15MetTrp: 0.15 ± 0.014
0.499MetTyr: 0.499 ± 0.033
0.0MetXaa: 0.0 ± 0.0
Asn
3.051AsnAla: 3.051 ± 0.084
0.341AsnCys: 0.341 ± 0.026
1.708AsnAsp: 1.708 ± 0.112
1.958AsnGlu: 1.958 ± 0.056
1.353AsnPhe: 1.353 ± 0.045
2.466AsnGly: 2.466 ± 0.077
0.713AsnHis: 0.713 ± 0.037
2.35AsnIle: 2.35 ± 0.067
1.16AsnLys: 1.16 ± 0.043
3.253AsnLeu: 3.253 ± 0.08
0.802AsnMet: 0.802 ± 0.035
1.133AsnAsn: 1.133 ± 0.056
2.261AsnPro: 2.261 ± 0.065
0.893AsnGln: 0.893 ± 0.048
2.241AsnArg: 2.241 ± 0.064
2.061AsnSer: 2.061 ± 0.073
1.937AsnThr: 1.937 ± 0.092
1.982AsnVal: 1.982 ± 0.077
0.387AsnTrp: 0.387 ± 0.024
0.973AsnTyr: 0.973 ± 0.044
0.0AsnXaa: 0.0 ± 0.0
Pro
4.058ProAla: 4.058 ± 0.101
0.368ProCys: 0.368 ± 0.03
2.991ProAsp: 2.991 ± 0.073
4.351ProGlu: 4.351 ± 0.121
2.063ProPhe: 2.063 ± 0.071
3.569ProGly: 3.569 ± 0.082
0.849ProHis: 0.849 ± 0.04
2.022ProIle: 2.022 ± 0.064
1.775ProLys: 1.775 ± 0.069
4.519ProLeu: 4.519 ± 0.114
1.163ProMet: 1.163 ± 0.044
1.123ProAsn: 1.123 ± 0.044
1.854ProPro: 1.854 ± 0.071
1.262ProGln: 1.262 ± 0.049
1.79ProArg: 1.79 ± 0.06
3.026ProSer: 3.026 ± 0.083
1.851ProThr: 1.851 ± 0.065
3.919ProVal: 3.919 ± 0.097
0.498ProTrp: 0.498 ± 0.029
1.173ProTyr: 1.173 ± 0.044
0.0ProXaa: 0.0 ± 0.0
Gln
2.754GlnAla: 2.754 ± 0.07
0.291GlnCys: 0.291 ± 0.022
1.244GlnAsp: 1.244 ± 0.042
2.305GlnGlu: 2.305 ± 0.074
1.116GlnPhe: 1.116 ± 0.044
2.046GlnGly: 2.046 ± 0.062
0.746GlnHis: 0.746 ± 0.045
1.671GlnIle: 1.671 ± 0.054
1.957GlnLys: 1.957 ± 0.067
3.182GlnLeu: 3.182 ± 0.096
0.825GlnMet: 0.825 ± 0.041
1.185GlnAsn: 1.185 ± 0.049
1.326GlnPro: 1.326 ± 0.051
1.387GlnGln: 1.387 ± 0.054
1.849GlnArg: 1.849 ± 0.067
1.987GlnSer: 1.987 ± 0.064
1.363GlnThr: 1.363 ± 0.046
1.847GlnVal: 1.847 ± 0.05
0.345GlnTrp: 0.345 ± 0.027
0.844GlnTyr: 0.844 ± 0.038
0.0GlnXaa: 0.0 ± 0.0
Arg
4.214ArgAla: 4.214 ± 0.098
0.607ArgCys: 0.607 ± 0.036
2.875ArgAsp: 2.875 ± 0.086
4.702ArgGlu: 4.702 ± 0.14
2.819ArgPhe: 2.819 ± 0.072
3.416ArgGly: 3.416 ± 0.096
1.528ArgHis: 1.528 ± 0.061
4.003ArgIle: 4.003 ± 0.105
3.312ArgLys: 3.312 ± 0.097
6.159ArgLeu: 6.159 ± 0.145
1.792ArgMet: 1.792 ± 0.061
2.288ArgAsn: 2.288 ± 0.06
2.493ArgPro: 2.493 ± 0.085
2.374ArgGln: 2.374 ± 0.079
3.755ArgArg: 3.755 ± 0.116
3.781ArgSer: 3.781 ± 0.1
2.898ArgThr: 2.898 ± 0.074
4.018ArgVal: 4.018 ± 0.088
0.642ArgTrp: 0.642 ± 0.036
1.937ArgTyr: 1.937 ± 0.063
0.0ArgXaa: 0.0 ± 0.0
Ser
6.334SerAla: 6.334 ± 0.142
0.807SerCys: 0.807 ± 0.039
3.197SerAsp: 3.197 ± 0.131
3.71SerGlu: 3.71 ± 0.094
3.17SerPhe: 3.17 ± 0.078
6.701SerGly: 6.701 ± 0.213
1.399SerHis: 1.399 ± 0.053
4.3SerIle: 4.3 ± 0.086
2.318SerLys: 2.318 ± 0.074
7.334SerLeu: 7.334 ± 0.119
2.016SerMet: 2.016 ± 0.062
1.851SerAsn: 1.851 ± 0.064
3.226SerPro: 3.226 ± 0.079
1.621SerGln: 1.621 ± 0.057
4.327SerArg: 4.327 ± 0.109
5.094SerSer: 5.094 ± 0.159
3.339SerThr: 3.339 ± 0.108
5.045SerVal: 5.045 ± 0.121
0.804SerTrp: 0.804 ± 0.038
1.856SerTyr: 1.856 ± 0.062
0.0SerXaa: 0.0 ± 0.0
Thr
5.45ThrAla: 5.45 ± 0.2
0.424ThrCys: 0.424 ± 0.025
2.898ThrAsp: 2.898 ± 0.145
3.001ThrGlu: 3.001 ± 0.088
1.787ThrPhe: 1.787 ± 0.069
5.448ThrGly: 5.448 ± 0.21
0.948ThrHis: 0.948 ± 0.042
3.715ThrIle: 3.715 ± 0.117
1.834ThrLys: 1.834 ± 0.059
6.122ThrLeu: 6.122 ± 0.213
1.316ThrMet: 1.316 ± 0.046
1.454ThrAsn: 1.454 ± 0.084
2.834ThrPro: 2.834 ± 0.067
1.143ThrGln: 1.143 ± 0.049
2.636ThrArg: 2.636 ± 0.069
2.974ThrSer: 2.974 ± 0.098
3.031ThrThr: 3.031 ± 0.143
4.357ThrVal: 4.357 ± 0.266
0.459ThrTrp: 0.459 ± 0.035
1.405ThrTyr: 1.405 ± 0.08
0.0ThrXaa: 0.0 ± 0.0
Val
6.074ValAla: 6.074 ± 0.114
0.693ValCys: 0.693 ± 0.04
3.929ValAsp: 3.929 ± 0.168
4.51ValGlu: 4.51 ± 0.087
3.107ValPhe: 3.107 ± 0.076
4.544ValGly: 4.544 ± 0.108
1.35ValHis: 1.35 ± 0.049
4.263ValIle: 4.263 ± 0.107
2.97ValLys: 2.97 ± 0.085
7.081ValLeu: 7.081 ± 0.125
1.893ValMet: 1.893 ± 0.065
2.278ValAsn: 2.278 ± 0.097
3.189ValPro: 3.189 ± 0.082
2.011ValGln: 2.011 ± 0.059
4.137ValArg: 4.137 ± 0.099
5.223ValSer: 5.223 ± 0.124
3.944ValThr: 3.944 ± 0.189
5.516ValVal: 5.516 ± 0.127
0.647ValTrp: 0.647 ± 0.039
1.817ValTyr: 1.817 ± 0.067
0.0ValXaa: 0.0 ± 0.0
Trp
0.735TrpAla: 0.735 ± 0.041
0.092TrpCys: 0.092 ± 0.012
0.518TrpAsp: 0.518 ± 0.032
0.57TrpGlu: 0.57 ± 0.035
0.514TrpPhe: 0.514 ± 0.032
0.614TrpGly: 0.614 ± 0.03
0.262TrpHis: 0.262 ± 0.021
0.61TrpIle: 0.61 ± 0.035
0.597TrpLys: 0.597 ± 0.034
1.162TrpLeu: 1.162 ± 0.058
0.363TrpMet: 0.363 ± 0.029
0.472TrpAsn: 0.472 ± 0.033
0.408TrpPro: 0.408 ± 0.028
0.476TrpGln: 0.476 ± 0.036
0.563TrpArg: 0.563 ± 0.039
0.607TrpSer: 0.607 ± 0.044
0.511TrpThr: 0.511 ± 0.031
0.59TrpVal: 0.59 ± 0.035
0.161TrpTrp: 0.161 ± 0.02
0.326TrpTyr: 0.326 ± 0.029
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.308TyrAla: 2.308 ± 0.062
0.358TyrCys: 0.358 ± 0.028
1.644TyrAsp: 1.644 ± 0.061
1.558TyrGlu: 1.558 ± 0.062
1.262TyrPhe: 1.262 ± 0.045
2.506TyrGly: 2.506 ± 0.069
0.654TyrHis: 0.654 ± 0.04
1.417TyrIle: 1.417 ± 0.05
0.847TyrLys: 0.847 ± 0.043
2.972TyrLeu: 2.972 ± 0.084
0.64TyrMet: 0.64 ± 0.036
0.943TyrAsn: 0.943 ± 0.038
1.306TyrPro: 1.306 ± 0.054
0.847TyrGln: 0.847 ± 0.041
2.306TyrArg: 2.306 ± 0.069
2.046TyrSer: 2.046 ± 0.067
1.513TyrThr: 1.513 ± 0.081
1.382TyrVal: 1.382 ± 0.05
0.308TyrTrp: 0.308 ± 0.026
0.914TyrTyr: 0.914 ± 0.051
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1750 proteins (594863 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski