Amino acid dipepetide frequency for Tortoise microvirus 29

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.098AlaAla: 6.098 ± 2.814
0.762AlaCys: 0.762 ± 0.726
3.811AlaAsp: 3.811 ± 2.312
3.049AlaGlu: 3.049 ± 0.707
2.287AlaPhe: 2.287 ± 1.391
3.811AlaGly: 3.811 ± 1.771
1.524AlaHis: 1.524 ± 1.042
2.287AlaIle: 2.287 ± 0.581
2.287AlaLys: 2.287 ± 2.029
6.86AlaLeu: 6.86 ± 1.517
0.762AlaMet: 0.762 ± 0.746
2.287AlaAsn: 2.287 ± 1.754
5.335AlaPro: 5.335 ± 1.291
3.049AlaGln: 3.049 ± 0.707
3.811AlaArg: 3.811 ± 1.431
5.335AlaSer: 5.335 ± 1.706
3.049AlaThr: 3.049 ± 1.182
4.573AlaVal: 4.573 ± 1.785
3.049AlaTrp: 3.049 ± 1.947
2.287AlaTyr: 2.287 ± 1.563
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.762CysAsp: 0.762 ± 0.521
0.762CysGlu: 0.762 ± 0.521
0.0CysPhe: 0.0 ± 0.0
2.287CysGly: 2.287 ± 2.179
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.287CysLeu: 2.287 ± 1.25
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.762CysPro: 0.762 ± 0.726
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.524CysThr: 1.524 ± 1.452
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.573AspAla: 4.573 ± 2.976
0.0AspCys: 0.0 ± 0.0
0.762AspAsp: 0.762 ± 0.726
0.762AspGlu: 0.762 ± 1.013
3.811AspPhe: 3.811 ± 1.015
5.335AspGly: 5.335 ± 1.69
0.0AspHis: 0.0 ± 0.0
0.762AspIle: 0.762 ± 0.521
3.049AspLys: 3.049 ± 1.301
8.384AspLeu: 8.384 ± 2.322
0.0AspMet: 0.0 ± 0.0
3.049AspAsn: 3.049 ± 1.529
3.811AspPro: 3.811 ± 1.433
3.811AspGln: 3.811 ± 2.909
3.811AspArg: 3.811 ± 1.734
3.049AspSer: 3.049 ± 1.028
0.762AspThr: 0.762 ± 0.521
3.811AspVal: 3.811 ± 1.839
0.0AspTrp: 0.0 ± 0.0
3.811AspTyr: 3.811 ± 1.433
0.0AspXaa: 0.0 ± 0.0
Glu
5.335GluAla: 5.335 ± 0.983
0.762GluCys: 0.762 ± 0.521
2.287GluAsp: 2.287 ± 1.202
3.811GluGlu: 3.811 ± 2.814
0.0GluPhe: 0.0 ± 0.0
3.049GluGly: 3.049 ± 1.249
1.524GluHis: 1.524 ± 0.625
3.811GluIle: 3.811 ± 2.814
3.811GluLys: 3.811 ± 1.931
6.098GluLeu: 6.098 ± 2.9
0.762GluMet: 0.762 ± 0.521
5.335GluAsn: 5.335 ± 2.205
0.0GluPro: 0.0 ± 0.0
5.335GluGln: 5.335 ± 1.744
3.049GluArg: 3.049 ± 1.567
2.287GluSer: 2.287 ± 1.391
4.573GluThr: 4.573 ± 1.49
5.335GluVal: 5.335 ± 2.477
0.762GluTrp: 0.762 ± 0.521
4.573GluTyr: 4.573 ± 1.162
0.0GluXaa: 0.0 ± 0.0
Phe
5.335PheAla: 5.335 ± 2.99
0.0PheCys: 0.0 ± 0.0
4.573PheAsp: 4.573 ± 1.662
3.049PheGlu: 3.049 ± 1.249
3.049PhePhe: 3.049 ± 2.191
2.287PheGly: 2.287 ± 1.075
1.524PheHis: 1.524 ± 0.848
2.287PheIle: 2.287 ± 1.563
0.762PheLys: 0.762 ± 0.726
0.762PheLeu: 0.762 ± 0.746
2.287PheMet: 2.287 ± 1.105
1.524PheAsn: 1.524 ± 0.625
0.762PhePro: 0.762 ± 1.119
1.524PheGln: 1.524 ± 0.625
0.762PheArg: 0.762 ± 0.726
3.049PheSer: 3.049 ± 1.507
1.524PheThr: 1.524 ± 0.625
2.287PheVal: 2.287 ± 0.92
2.287PheTrp: 2.287 ± 0.581
0.762PheTyr: 0.762 ± 0.726
0.0PheXaa: 0.0 ± 0.0
Gly
3.049GlyAla: 3.049 ± 1.07
0.762GlyCys: 0.762 ± 0.726
7.622GlyAsp: 7.622 ± 1.257
3.811GlyGlu: 3.811 ± 1.45
3.049GlyPhe: 3.049 ± 1.321
6.098GlyGly: 6.098 ± 1.94
0.762GlyHis: 0.762 ± 0.521
5.335GlyIle: 5.335 ± 1.861
4.573GlyLys: 4.573 ± 1.623
3.049GlyLeu: 3.049 ± 1.529
0.762GlyMet: 0.762 ± 1.013
3.049GlyAsn: 3.049 ± 1.301
0.0GlyPro: 0.0 ± 0.0
1.524GlyGln: 1.524 ± 1.128
3.811GlyArg: 3.811 ± 2.074
3.049GlySer: 3.049 ± 1.947
5.335GlyThr: 5.335 ± 2.926
2.287GlyVal: 2.287 ± 1.075
0.762GlyTrp: 0.762 ± 0.726
3.049GlyTyr: 3.049 ± 1.947
0.0GlyXaa: 0.0 ± 0.0
His
0.762HisAla: 0.762 ± 0.726
0.0HisCys: 0.0 ± 0.0
1.524HisAsp: 1.524 ± 1.042
0.762HisGlu: 0.762 ± 0.726
2.287HisPhe: 2.287 ± 0.892
1.524HisGly: 1.524 ± 1.042
0.762HisHis: 0.762 ± 0.521
0.0HisIle: 0.0 ± 0.0
3.049HisLys: 3.049 ± 1.07
1.524HisLeu: 1.524 ± 1.042
0.762HisMet: 0.762 ± 0.521
0.762HisAsn: 0.762 ± 0.521
1.524HisPro: 1.524 ± 1.452
0.762HisGln: 0.762 ± 0.726
0.762HisArg: 0.762 ± 0.726
0.762HisSer: 0.762 ± 0.521
0.0HisThr: 0.0 ± 0.0
2.287HisVal: 2.287 ± 1.25
0.0HisTrp: 0.0 ± 0.0
0.762HisTyr: 0.762 ± 0.521
0.0HisXaa: 0.0 ± 0.0
Ile
2.287IleAla: 2.287 ± 0.92
0.0IleCys: 0.0 ± 0.0
1.524IleAsp: 1.524 ± 1.042
1.524IleGlu: 1.524 ± 0.994
1.524IlePhe: 1.524 ± 0.625
1.524IleGly: 1.524 ± 0.625
2.287IleHis: 2.287 ± 0.892
1.524IleIle: 1.524 ± 0.994
5.335IleLys: 5.335 ± 0.678
1.524IleLeu: 1.524 ± 0.764
5.335IleMet: 5.335 ± 1.554
4.573IleAsn: 4.573 ± 2.618
2.287IlePro: 2.287 ± 1.221
1.524IleGln: 1.524 ± 0.848
0.762IleArg: 0.762 ± 0.521
3.049IleSer: 3.049 ± 2.085
1.524IleThr: 1.524 ± 1.138
0.0IleVal: 0.0 ± 0.0
0.0IleTrp: 0.0 ± 0.0
1.524IleTyr: 1.524 ± 0.764
0.0IleXaa: 0.0 ± 0.0
Lys
4.573LysAla: 4.573 ± 1.91
1.524LysCys: 1.524 ± 1.452
2.287LysAsp: 2.287 ± 1.391
5.335LysGlu: 5.335 ± 1.562
3.049LysPhe: 3.049 ± 1.301
2.287LysGly: 2.287 ± 0.581
1.524LysHis: 1.524 ± 1.452
2.287LysIle: 2.287 ± 0.892
7.622LysLys: 7.622 ± 4.178
6.098LysLeu: 6.098 ± 2.653
3.811LysMet: 3.811 ± 1.347
5.335LysAsn: 5.335 ± 1.681
1.524LysPro: 1.524 ± 1.096
3.811LysGln: 3.811 ± 1.637
5.335LysArg: 5.335 ± 3.291
3.811LysSer: 3.811 ± 2.035
3.811LysThr: 3.811 ± 1.109
3.049LysVal: 3.049 ± 2.55
0.0LysTrp: 0.0 ± 0.0
4.573LysTyr: 4.573 ± 1.189
0.0LysXaa: 0.0 ± 0.0
Leu
3.049LeuAla: 3.049 ± 1.182
0.0LeuCys: 0.0 ± 0.0
3.811LeuAsp: 3.811 ± 1.791
3.811LeuGlu: 3.811 ± 1.637
0.762LeuPhe: 0.762 ± 0.726
6.86LeuGly: 6.86 ± 0.801
0.762LeuHis: 0.762 ± 0.726
2.287LeuIle: 2.287 ± 0.581
6.86LeuLys: 6.86 ± 3.053
3.811LeuLeu: 3.811 ± 1.456
1.524LeuMet: 1.524 ± 1.096
5.335LeuAsn: 5.335 ± 1.567
3.049LeuPro: 3.049 ± 1.321
7.622LeuGln: 7.622 ± 2.515
7.622LeuArg: 7.622 ± 2.907
6.098LeuSer: 6.098 ± 1.928
2.287LeuThr: 2.287 ± 0.581
5.335LeuVal: 5.335 ± 2.214
0.762LeuTrp: 0.762 ± 0.521
3.811LeuTyr: 3.811 ± 1.749
0.0LeuXaa: 0.0 ± 0.0
Met
1.524MetAla: 1.524 ± 0.625
0.0MetCys: 0.0 ± 0.0
2.287MetAsp: 2.287 ± 1.621
3.811MetGlu: 3.811 ± 1.147
0.762MetPhe: 0.762 ± 0.726
1.524MetGly: 1.524 ± 1.042
0.762MetHis: 0.762 ± 0.521
0.0MetIle: 0.0 ± 0.0
2.287MetLys: 2.287 ± 1.391
0.762MetLeu: 0.762 ± 1.119
0.0MetMet: 0.0 ± 0.0
0.762MetAsn: 0.762 ± 0.746
1.524MetPro: 1.524 ± 1.042
3.049MetGln: 3.049 ± 2.574
1.524MetArg: 1.524 ± 0.625
6.098MetSer: 6.098 ± 1.774
1.524MetThr: 1.524 ± 1.492
2.287MetVal: 2.287 ± 1.25
0.0MetTrp: 0.0 ± 0.0
0.762MetTyr: 0.762 ± 0.746
0.0MetXaa: 0.0 ± 0.0
Asn
2.287AsnAla: 2.287 ± 1.25
0.0AsnCys: 0.0 ± 0.0
2.287AsnAsp: 2.287 ± 1.221
6.86AsnGlu: 6.86 ± 3.029
0.762AsnPhe: 0.762 ± 0.726
3.049AsnGly: 3.049 ± 1.249
0.762AsnHis: 0.762 ± 0.521
2.287AsnIle: 2.287 ± 1.075
2.287AsnLys: 2.287 ± 1.422
5.335AsnLeu: 5.335 ± 3.481
1.524AsnMet: 1.524 ± 0.625
3.049AsnAsn: 3.049 ± 2.977
3.811AsnPro: 3.811 ± 1.431
1.524AsnGln: 1.524 ± 1.128
3.811AsnArg: 3.811 ± 1.45
3.811AsnSer: 3.811 ± 2.152
3.811AsnThr: 3.811 ± 1.147
5.335AsnVal: 5.335 ± 1.291
0.762AsnTrp: 0.762 ± 0.521
4.573AsnTyr: 4.573 ± 2.598
0.0AsnXaa: 0.0 ± 0.0
Pro
1.524ProAla: 1.524 ± 1.096
1.524ProCys: 1.524 ± 1.452
3.811ProAsp: 3.811 ± 1.772
3.049ProGlu: 3.049 ± 0.707
1.524ProPhe: 1.524 ± 1.042
4.573ProGly: 4.573 ± 2.15
1.524ProHis: 1.524 ± 0.625
2.287ProIle: 2.287 ± 2.179
4.573ProLys: 4.573 ± 1.073
2.287ProLeu: 2.287 ± 1.3
0.762ProMet: 0.762 ± 0.521
2.287ProAsn: 2.287 ± 1.075
1.524ProPro: 1.524 ± 0.625
6.098ProGln: 6.098 ± 1.333
2.287ProArg: 2.287 ± 1.085
2.287ProSer: 2.287 ± 1.621
3.049ProThr: 3.049 ± 1.593
3.811ProVal: 3.811 ± 2.074
0.762ProTrp: 0.762 ± 0.746
2.287ProTyr: 2.287 ± 1.3
0.0ProXaa: 0.0 ± 0.0
Gln
6.098GlnAla: 6.098 ± 2.593
0.0GlnCys: 0.0 ± 0.0
2.287GlnAsp: 2.287 ± 0.892
3.811GlnGlu: 3.811 ± 1.257
2.287GlnPhe: 2.287 ± 0.581
5.335GlnGly: 5.335 ± 1.239
0.762GlnHis: 0.762 ± 0.521
2.287GlnIle: 2.287 ± 1.418
4.573GlnLys: 4.573 ± 1.623
3.811GlnLeu: 3.811 ± 1.771
3.811GlnMet: 3.811 ± 2.219
3.049GlnAsn: 3.049 ± 1.857
0.762GlnPro: 0.762 ± 0.746
1.524GlnGln: 1.524 ± 0.848
3.811GlnArg: 3.811 ± 2.15
2.287GlnSer: 2.287 ± 2.01
3.811GlnThr: 3.811 ± 1.843
3.049GlnVal: 3.049 ± 1.07
0.762GlnTrp: 0.762 ± 0.521
3.811GlnTyr: 3.811 ± 2.062
0.0GlnXaa: 0.0 ± 0.0
Arg
1.524ArgAla: 1.524 ± 0.625
0.762ArgCys: 0.762 ± 0.726
3.811ArgAsp: 3.811 ± 1.357
3.811ArgGlu: 3.811 ± 1.637
3.811ArgPhe: 3.811 ± 1.799
1.524ArgGly: 1.524 ± 1.096
0.0ArgHis: 0.0 ± 0.0
3.049ArgIle: 3.049 ± 1.45
6.86ArgLys: 6.86 ± 1.817
5.335ArgLeu: 5.335 ± 1.707
1.524ArgMet: 1.524 ± 1.32
1.524ArgAsn: 1.524 ± 0.848
3.811ArgPro: 3.811 ± 1.372
4.573ArgGln: 4.573 ± 2.391
3.049ArgArg: 3.049 ± 0.695
6.098ArgSer: 6.098 ± 2.116
3.049ArgThr: 3.049 ± 1.249
0.762ArgVal: 0.762 ± 0.521
0.0ArgTrp: 0.0 ± 0.0
2.287ArgTyr: 2.287 ± 0.892
0.0ArgXaa: 0.0 ± 0.0
Ser
5.335SerAla: 5.335 ± 1.706
0.762SerCys: 0.762 ± 0.521
3.049SerAsp: 3.049 ± 1.07
6.098SerGlu: 6.098 ± 2.873
3.811SerPhe: 3.811 ± 1.433
4.573SerGly: 4.573 ± 2.334
1.524SerHis: 1.524 ± 1.042
3.049SerIle: 3.049 ± 1.249
1.524SerLys: 1.524 ± 0.848
6.86SerLeu: 6.86 ± 1.343
0.762SerMet: 0.762 ± 0.726
2.287SerAsn: 2.287 ± 1.25
6.098SerPro: 6.098 ± 2.11
5.335SerGln: 5.335 ± 2.683
4.573SerArg: 4.573 ± 1.13
9.909SerSer: 9.909 ± 2.806
4.573SerThr: 4.573 ± 2.304
3.811SerVal: 3.811 ± 1.799
1.524SerTrp: 1.524 ± 0.848
0.762SerTyr: 0.762 ± 0.746
0.0SerXaa: 0.0 ± 0.0
Thr
3.049ThrAla: 3.049 ± 1.301
0.762ThrCys: 0.762 ± 0.726
1.524ThrAsp: 1.524 ± 0.994
6.098ThrGlu: 6.098 ± 1.42
5.335ThrPhe: 5.335 ± 1.427
2.287ThrGly: 2.287 ± 0.892
0.0ThrHis: 0.0 ± 0.0
3.049ThrIle: 3.049 ± 1.321
1.524ThrLys: 1.524 ± 1.452
2.287ThrLeu: 2.287 ± 1.202
3.049ThrMet: 3.049 ± 1.384
3.811ThrAsn: 3.811 ± 1.675
4.573ThrPro: 4.573 ± 2.935
1.524ThrGln: 1.524 ± 1.128
2.287ThrArg: 2.287 ± 1.418
3.811ThrSer: 3.811 ± 1.45
3.811ThrThr: 3.811 ± 1.2
1.524ThrVal: 1.524 ± 0.994
0.0ThrTrp: 0.0 ± 0.0
2.287ThrTyr: 2.287 ± 0.581
0.0ThrXaa: 0.0 ± 0.0
Val
3.811ValAla: 3.811 ± 0.948
0.0ValCys: 0.0 ± 0.0
2.287ValAsp: 2.287 ± 1.468
1.524ValGlu: 1.524 ± 2.027
2.287ValPhe: 2.287 ± 1.221
1.524ValGly: 1.524 ± 1.452
3.049ValHis: 3.049 ± 1.947
1.524ValIle: 1.524 ± 1.042
3.811ValLys: 3.811 ± 2.165
1.524ValLeu: 1.524 ± 0.625
1.524ValMet: 1.524 ± 1.042
5.335ValAsn: 5.335 ± 2.061
6.86ValPro: 6.86 ± 2.677
2.287ValGln: 2.287 ± 0.581
3.049ValArg: 3.049 ± 1.368
6.098ValSer: 6.098 ± 2.989
2.287ValThr: 2.287 ± 0.892
1.524ValVal: 1.524 ± 1.28
0.0ValTrp: 0.0 ± 0.0
2.287ValTyr: 2.287 ± 1.075
0.0ValXaa: 0.0 ± 0.0
Trp
0.762TrpAla: 0.762 ± 0.726
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
1.524TrpHis: 1.524 ± 0.625
0.0TrpIle: 0.0 ± 0.0
2.287TrpLys: 2.287 ± 2.179
0.762TrpLeu: 0.762 ± 0.521
0.0TrpMet: 0.0 ± 0.0
0.762TrpAsn: 0.762 ± 0.746
2.287TrpPro: 2.287 ± 1.563
1.524TrpGln: 1.524 ± 0.764
0.0TrpArg: 0.0 ± 0.0
0.762TrpSer: 0.762 ± 0.521
0.762TrpThr: 0.762 ± 0.726
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.762TrpTyr: 0.762 ± 0.746
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.335TyrAla: 5.335 ± 1.497
0.762TyrCys: 0.762 ± 0.521
3.049TyrAsp: 3.049 ± 2.258
0.762TyrGlu: 0.762 ± 0.726
0.762TyrPhe: 0.762 ± 0.521
2.287TyrGly: 2.287 ± 0.581
0.0TyrHis: 0.0 ± 0.0
1.524TyrIle: 1.524 ± 1.138
4.573TyrLys: 4.573 ± 1.094
6.098TyrLeu: 6.098 ± 1.849
1.524TyrMet: 1.524 ± 0.764
3.811TyrAsn: 3.811 ± 1.109
1.524TyrPro: 1.524 ± 0.764
1.524TyrGln: 1.524 ± 0.625
3.049TyrArg: 3.049 ± 1.118
4.573TyrSer: 4.573 ± 2.101
1.524TyrThr: 1.524 ± 1.28
1.524TyrVal: 1.524 ± 0.625
0.762TyrTrp: 0.762 ± 0.521
5.335TyrTyr: 5.335 ± 0.678
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1313 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski