Amino acid dipepetide frequency for Selenomonas noxia ATCC 43541

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.53AlaAla: 15.53 ± 0.272
1.176AlaCys: 1.176 ± 0.053
6.557AlaAsp: 6.557 ± 0.106
8.476AlaGlu: 8.476 ± 0.152
3.657AlaPhe: 3.657 ± 0.076
8.883AlaGly: 8.883 ± 0.148
2.42AlaHis: 2.42 ± 0.068
5.367AlaIle: 5.367 ± 0.099
4.429AlaLys: 4.429 ± 0.081
10.754AlaLeu: 10.754 ± 0.174
2.911AlaMet: 2.911 ± 0.066
2.741AlaAsn: 2.741 ± 0.083
3.754AlaPro: 3.754 ± 0.082
3.77AlaGln: 3.77 ± 0.091
6.513AlaArg: 6.513 ± 0.142
4.771AlaSer: 4.771 ± 0.108
3.618AlaThr: 3.618 ± 0.076
8.625AlaVal: 8.625 ± 0.134
0.972AlaTrp: 0.972 ± 0.039
3.309AlaTyr: 3.309 ± 0.083
0.0AlaXaa: 0.0 ± 0.0
Cys
1.227CysAla: 1.227 ± 0.047
0.186CysCys: 0.186 ± 0.017
0.576CysAsp: 0.576 ± 0.036
0.57CysGlu: 0.57 ± 0.031
0.361CysPhe: 0.361 ± 0.022
1.171CysGly: 1.171 ± 0.044
0.274CysHis: 0.274 ± 0.023
0.745CysIle: 0.745 ± 0.035
0.321CysLys: 0.321 ± 0.024
0.85CysLeu: 0.85 ± 0.035
0.344CysMet: 0.344 ± 0.023
0.235CysAsn: 0.235 ± 0.019
0.496CysPro: 0.496 ± 0.03
0.224CysGln: 0.224 ± 0.019
0.799CysArg: 0.799 ± 0.039
0.576CysSer: 0.576 ± 0.03
0.603CysThr: 0.603 ± 0.032
0.695CysVal: 0.695 ± 0.033
0.084CysTrp: 0.084 ± 0.012
0.36CysTyr: 0.36 ± 0.026
0.0CysXaa: 0.0 ± 0.0
Asp
6.586AspAla: 6.586 ± 0.104
0.546AspCys: 0.546 ± 0.034
2.913AspAsp: 2.913 ± 0.075
4.071AspGlu: 4.071 ± 0.084
2.593AspPhe: 2.593 ± 0.066
4.555AspGly: 4.555 ± 0.106
1.096AspHis: 1.096 ± 0.045
4.179AspIle: 4.179 ± 0.077
2.203AspLys: 2.203 ± 0.065
4.792AspLeu: 4.792 ± 0.085
1.689AspMet: 1.689 ± 0.049
1.449AspAsn: 1.449 ± 0.054
2.211AspPro: 2.211 ± 0.061
1.16AspGln: 1.16 ± 0.04
3.102AspArg: 3.102 ± 0.067
2.284AspSer: 2.284 ± 0.065
3.077AspThr: 3.077 ± 0.085
4.365AspVal: 4.365 ± 0.085
0.577AspTrp: 0.577 ± 0.031
2.251AspTyr: 2.251 ± 0.066
0.0AspXaa: 0.0 ± 0.0
Glu
6.255GluAla: 6.255 ± 0.124
0.56GluCys: 0.56 ± 0.032
3.454GluAsp: 3.454 ± 0.08
6.032GluGlu: 6.032 ± 0.142
1.952GluPhe: 1.952 ± 0.057
4.599GluGly: 4.599 ± 0.081
1.709GluHis: 1.709 ± 0.056
5.025GluIle: 5.025 ± 0.095
4.135GluLys: 4.135 ± 0.097
6.311GluLeu: 6.311 ± 0.117
2.259GluMet: 2.259 ± 0.068
2.959GluAsn: 2.959 ± 0.073
1.955GluPro: 1.955 ± 0.067
2.696GluGln: 2.696 ± 0.074
5.019GluArg: 5.019 ± 0.104
2.794GluSer: 2.794 ± 0.06
3.859GluThr: 3.859 ± 0.079
4.057GluVal: 4.057 ± 0.084
0.496GluTrp: 0.496 ± 0.032
1.934GluTyr: 1.934 ± 0.056
0.0GluXaa: 0.0 ± 0.0
Phe
3.851PheAla: 3.851 ± 0.078
0.496PheCys: 0.496 ± 0.028
2.351PheAsp: 2.351 ± 0.068
1.853PheGlu: 1.853 ± 0.061
1.952PhePhe: 1.952 ± 0.062
3.191PheGly: 3.191 ± 0.076
0.934PheHis: 0.934 ± 0.044
2.428PheIle: 2.428 ± 0.081
1.134PheLys: 1.134 ± 0.047
3.839PheLeu: 3.839 ± 0.102
1.026PheMet: 1.026 ± 0.045
1.128PheAsn: 1.128 ± 0.04
1.473PhePro: 1.473 ± 0.052
1.074PheGln: 1.074 ± 0.044
2.106PheArg: 2.106 ± 0.059
2.744PheSer: 2.744 ± 0.069
2.098PheThr: 2.098 ± 0.055
2.593PheVal: 2.593 ± 0.077
0.425PheTrp: 0.425 ± 0.029
1.332PheTyr: 1.332 ± 0.05
0.0PheXaa: 0.0 ± 0.0
Gly
8.357GlyAla: 8.357 ± 0.135
1.039GlyCys: 1.039 ± 0.049
4.131GlyAsp: 4.131 ± 0.086
4.763GlyGlu: 4.763 ± 0.089
3.015GlyPhe: 3.015 ± 0.079
6.382GlyGly: 6.382 ± 0.148
1.654GlyHis: 1.654 ± 0.044
6.074GlyIle: 6.074 ± 0.101
4.17GlyLys: 4.17 ± 0.1
6.432GlyLeu: 6.432 ± 0.1
2.65GlyMet: 2.65 ± 0.075
2.418GlyAsn: 2.418 ± 0.093
1.478GlyPro: 1.478 ± 0.053
2.074GlyGln: 2.074 ± 0.054
5.067GlyArg: 5.067 ± 0.09
4.087GlySer: 4.087 ± 0.108
5.286GlyThr: 5.286 ± 0.113
5.73GlyVal: 5.73 ± 0.107
0.786GlyTrp: 0.786 ± 0.035
2.689GlyTyr: 2.689 ± 0.071
0.0GlyXaa: 0.0 ± 0.0
His
2.339HisAla: 2.339 ± 0.061
0.275HisCys: 0.275 ± 0.018
1.155HisAsp: 1.155 ± 0.044
1.47HisGlu: 1.47 ± 0.044
0.945HisPhe: 0.945 ± 0.042
1.868HisGly: 1.868 ± 0.057
0.48HisHis: 0.48 ± 0.031
1.723HisIle: 1.723 ± 0.054
0.697HisLys: 0.697 ± 0.031
2.063HisLeu: 2.063 ± 0.059
0.689HisMet: 0.689 ± 0.034
0.654HisAsn: 0.654 ± 0.033
1.298HisPro: 1.298 ± 0.044
0.48HisGln: 0.48 ± 0.025
1.269HisArg: 1.269 ± 0.048
0.975HisSer: 0.975 ± 0.037
1.362HisThr: 1.362 ± 0.049
1.602HisVal: 1.602 ± 0.054
0.202HisTrp: 0.202 ± 0.021
0.74HisTyr: 0.74 ± 0.033
0.0HisXaa: 0.0 ± 0.0
Ile
7.273IleAla: 7.273 ± 0.13
0.821IleCys: 0.821 ± 0.043
3.969IleAsp: 3.969 ± 0.092
4.182IleGlu: 4.182 ± 0.086
2.512IlePhe: 2.512 ± 0.073
5.45IleGly: 5.45 ± 0.11
1.376IleHis: 1.376 ± 0.047
4.031IleIle: 4.031 ± 0.096
2.334IleLys: 2.334 ± 0.063
6.252IleLeu: 6.252 ± 0.123
1.627IleMet: 1.627 ± 0.054
2.003IleAsn: 2.003 ± 0.067
2.949IlePro: 2.949 ± 0.075
1.74IleGln: 1.74 ± 0.055
4.03IleArg: 4.03 ± 0.087
3.824IleSer: 3.824 ± 0.083
3.528IleThr: 3.528 ± 0.079
4.936IleVal: 4.936 ± 0.093
0.5IleTrp: 0.5 ± 0.031
2.066IleTyr: 2.066 ± 0.067
0.0IleXaa: 0.0 ± 0.0
Lys
4.03LysAla: 4.03 ± 0.098
0.32LysCys: 0.32 ± 0.021
2.458LysAsp: 2.458 ± 0.077
3.842LysGlu: 3.842 ± 0.094
1.362LysPhe: 1.362 ± 0.048
3.221LysGly: 3.221 ± 0.079
0.842LysHis: 0.842 ± 0.038
3.131LysIle: 3.131 ± 0.062
3.318LysLys: 3.318 ± 0.095
3.567LysLeu: 3.567 ± 0.08
1.419LysMet: 1.419 ± 0.05
2.0LysAsn: 2.0 ± 0.072
1.456LysPro: 1.456 ± 0.047
1.268LysGln: 1.268 ± 0.046
2.607LysArg: 2.607 ± 0.066
2.256LysSer: 2.256 ± 0.07
2.585LysThr: 2.585 ± 0.074
2.603LysVal: 2.603 ± 0.069
0.374LysTrp: 0.374 ± 0.026
1.559LysTyr: 1.559 ± 0.062
0.0LysXaa: 0.0 ± 0.0
Leu
10.428LeuAla: 10.428 ± 0.165
1.163LeuCys: 1.163 ± 0.049
4.914LeuAsp: 4.914 ± 0.104
4.841LeuGlu: 4.841 ± 0.08
3.657LeuPhe: 3.657 ± 0.095
7.016LeuGly: 7.016 ± 0.12
2.168LeuHis: 2.168 ± 0.064
5.262LeuIle: 5.262 ± 0.114
3.713LeuLys: 3.713 ± 0.088
9.421LeuLeu: 9.421 ± 0.194
2.625LeuMet: 2.625 ± 0.065
2.733LeuAsn: 2.733 ± 0.079
4.744LeuPro: 4.744 ± 0.103
2.628LeuGln: 2.628 ± 0.079
6.602LeuArg: 6.602 ± 0.113
6.052LeuSer: 6.052 ± 0.096
5.884LeuThr: 5.884 ± 0.102
6.071LeuVal: 6.071 ± 0.1
0.784LeuTrp: 0.784 ± 0.033
2.891LeuTyr: 2.891 ± 0.074
0.0LeuXaa: 0.0 ± 0.0
Met
2.813MetAla: 2.813 ± 0.066
0.235MetCys: 0.235 ± 0.02
1.756MetAsp: 1.756 ± 0.051
2.141MetGlu: 2.141 ± 0.063
0.859MetPhe: 0.859 ± 0.041
2.211MetGly: 2.211 ± 0.061
0.636MetHis: 0.636 ± 0.032
1.787MetIle: 1.787 ± 0.056
1.759MetLys: 1.759 ± 0.048
2.76MetLeu: 2.76 ± 0.064
1.001MetMet: 1.001 ± 0.043
1.239MetAsn: 1.239 ± 0.048
1.359MetPro: 1.359 ± 0.047
1.164MetGln: 1.164 ± 0.049
2.133MetArg: 2.133 ± 0.063
1.562MetSer: 1.562 ± 0.053
1.944MetThr: 1.944 ± 0.052
1.664MetVal: 1.664 ± 0.049
0.189MetTrp: 0.189 ± 0.019
0.668MetTyr: 0.668 ± 0.036
0.0MetXaa: 0.0 ± 0.0
Asn
3.497AsnAla: 3.497 ± 0.089
0.321AsnCys: 0.321 ± 0.024
1.631AsnAsp: 1.631 ± 0.057
1.942AsnGlu: 1.942 ± 0.054
1.279AsnPhe: 1.279 ± 0.046
2.531AsnGly: 2.531 ± 0.105
0.587AsnHis: 0.587 ± 0.029
2.682AsnIle: 2.682 ± 0.081
1.301AsnLys: 1.301 ± 0.054
3.018AsnLeu: 3.018 ± 0.076
1.015AsnMet: 1.015 ± 0.043
1.037AsnAsn: 1.037 ± 0.047
1.815AsnPro: 1.815 ± 0.053
0.772AsnGln: 0.772 ± 0.033
1.689AsnArg: 1.689 ± 0.057
1.304AsnSer: 1.304 ± 0.051
1.791AsnThr: 1.791 ± 0.066
2.611AsnVal: 2.611 ± 0.072
0.297AsnTrp: 0.297 ± 0.022
1.204AsnTyr: 1.204 ± 0.07
0.0AsnXaa: 0.0 ± 0.0
Pro
4.351ProAla: 4.351 ± 0.097
0.38ProCys: 0.38 ± 0.029
2.31ProAsp: 2.31 ± 0.066
3.097ProGlu: 3.097 ± 0.072
1.634ProPhe: 1.634 ± 0.059
2.601ProGly: 2.601 ± 0.07
1.096ProHis: 1.096 ± 0.043
2.318ProIle: 2.318 ± 0.063
1.524ProLys: 1.524 ± 0.047
3.754ProLeu: 3.754 ± 0.092
1.077ProMet: 1.077 ± 0.043
1.382ProAsn: 1.382 ± 0.055
1.6ProPro: 1.6 ± 0.065
1.303ProGln: 1.303 ± 0.049
1.993ProArg: 1.993 ± 0.049
2.035ProSer: 2.035 ± 0.053
1.989ProThr: 1.989 ± 0.057
3.233ProVal: 3.233 ± 0.074
0.388ProTrp: 0.388 ± 0.024
1.441ProTyr: 1.441 ± 0.048
0.0ProXaa: 0.0 ± 0.0
Gln
2.768GlnAla: 2.768 ± 0.069
0.226GlnCys: 0.226 ± 0.022
1.441GlnAsp: 1.441 ± 0.048
2.447GlnGlu: 2.447 ± 0.073
0.942GlnPhe: 0.942 ± 0.034
2.062GlnGly: 2.062 ± 0.063
0.63GlnHis: 0.63 ± 0.029
2.038GlnIle: 2.038 ± 0.06
1.783GlnLys: 1.783 ± 0.059
2.871GlnLeu: 2.871 ± 0.067
1.059GlnMet: 1.059 ± 0.048
1.236GlnAsn: 1.236 ± 0.053
1.069GlnPro: 1.069 ± 0.04
1.246GlnGln: 1.246 ± 0.059
2.197GlnArg: 2.197 ± 0.064
1.518GlnSer: 1.518 ± 0.05
1.798GlnThr: 1.798 ± 0.059
1.678GlnVal: 1.678 ± 0.048
0.247GlnTrp: 0.247 ± 0.025
0.951GlnTyr: 0.951 ± 0.036
0.0GlnXaa: 0.0 ± 0.0
Arg
6.898ArgAla: 6.898 ± 0.142
0.611ArgCys: 0.611 ± 0.033
3.264ArgAsp: 3.264 ± 0.074
4.671ArgGlu: 4.671 ± 0.099
2.176ArgPhe: 2.176 ± 0.059
4.438ArgGly: 4.438 ± 0.101
1.33ArgHis: 1.33 ± 0.045
4.535ArgIle: 4.535 ± 0.094
2.628ArgLys: 2.628 ± 0.078
5.824ArgLeu: 5.824 ± 0.102
2.205ArgMet: 2.205 ± 0.062
1.847ArgAsn: 1.847 ± 0.065
2.288ArgPro: 2.288 ± 0.063
2.049ArgGln: 2.049 ± 0.062
4.849ArgArg: 4.849 ± 0.11
3.261ArgSer: 3.261 ± 0.065
3.662ArgThr: 3.662 ± 0.078
4.181ArgVal: 4.181 ± 0.086
0.579ArgTrp: 0.579 ± 0.03
2.135ArgTyr: 2.135 ± 0.065
0.0ArgXaa: 0.0 ± 0.0
Ser
5.674SerAla: 5.674 ± 0.107
0.536SerCys: 0.536 ± 0.03
3.043SerAsp: 3.043 ± 0.076
3.016SerGlu: 3.016 ± 0.074
2.483SerPhe: 2.483 ± 0.068
4.701SerGly: 4.701 ± 0.101
1.122SerHis: 1.122 ± 0.043
3.439SerIle: 3.439 ± 0.08
1.928SerLys: 1.928 ± 0.054
4.763SerLeu: 4.763 ± 0.1
1.589SerMet: 1.589 ± 0.046
1.553SerAsn: 1.553 ± 0.062
2.098SerPro: 2.098 ± 0.057
1.19SerGln: 1.19 ± 0.045
2.794SerArg: 2.794 ± 0.081
3.016SerSer: 3.016 ± 0.088
2.572SerThr: 2.572 ± 0.072
4.004SerVal: 4.004 ± 0.09
0.474SerTrp: 0.474 ± 0.028
2.084SerTyr: 2.084 ± 0.056
0.0SerXaa: 0.0 ± 0.0
Thr
6.462ThrAla: 6.462 ± 0.118
0.469ThrCys: 0.469 ± 0.027
3.131ThrAsp: 3.131 ± 0.081
3.606ThrGlu: 3.606 ± 0.077
1.979ThrPhe: 1.979 ± 0.056
4.957ThrGly: 4.957 ± 0.102
1.217ThrHis: 1.217 ± 0.043
3.527ThrIle: 3.527 ± 0.081
2.296ThrLys: 2.296 ± 0.076
5.145ThrLeu: 5.145 ± 0.114
1.54ThrMet: 1.54 ± 0.049
1.696ThrAsn: 1.696 ± 0.063
2.666ThrPro: 2.666 ± 0.066
1.554ThrGln: 1.554 ± 0.051
2.863ThrArg: 2.863 ± 0.072
2.867ThrSer: 2.867 ± 0.082
2.79ThrThr: 2.79 ± 0.089
4.349ThrVal: 4.349 ± 0.091
0.466ThrTrp: 0.466 ± 0.028
1.752ThrTyr: 1.752 ± 0.067
0.0ThrXaa: 0.0 ± 0.0
Val
5.665ValAla: 5.665 ± 0.11
0.912ValCys: 0.912 ± 0.042
3.893ValAsp: 3.893 ± 0.08
4.133ValGlu: 4.133 ± 0.096
2.965ValPhe: 2.965 ± 0.07
5.013ValGly: 5.013 ± 0.103
1.637ValHis: 1.637 ± 0.055
4.586ValIle: 4.586 ± 0.085
2.973ValLys: 2.973 ± 0.081
7.219ValLeu: 7.219 ± 0.128
2.022ValMet: 2.022 ± 0.063
2.431ValAsn: 2.431 ± 0.079
3.248ValPro: 3.248 ± 0.079
2.316ValGln: 2.316 ± 0.059
4.998ValArg: 4.998 ± 0.095
4.211ValSer: 4.211 ± 0.078
4.372ValThr: 4.372 ± 0.111
5.064ValVal: 5.064 ± 0.114
0.593ValTrp: 0.593 ± 0.03
2.386ValTyr: 2.386 ± 0.063
0.0ValXaa: 0.0 ± 0.0
Trp
0.746TrpAla: 0.746 ± 0.035
0.075TrpCys: 0.075 ± 0.011
0.484TrpAsp: 0.484 ± 0.028
0.622TrpGlu: 0.622 ± 0.035
0.27TrpPhe: 0.27 ± 0.019
0.652TrpGly: 0.652 ± 0.034
0.251TrpHis: 0.251 ± 0.018
0.506TrpIle: 0.506 ± 0.031
0.447TrpLys: 0.447 ± 0.031
0.889TrpLeu: 0.889 ± 0.038
0.344TrpMet: 0.344 ± 0.023
0.449TrpAsn: 0.449 ± 0.031
0.22TrpPro: 0.22 ± 0.018
0.449TrpGln: 0.449 ± 0.028
0.638TrpArg: 0.638 ± 0.032
0.476TrpSer: 0.476 ± 0.028
0.501TrpThr: 0.501 ± 0.032
0.468TrpVal: 0.468 ± 0.029
0.11TrpTrp: 0.11 ± 0.013
0.288TrpTyr: 0.288 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.486TyrAla: 3.486 ± 0.078
0.348TyrCys: 0.348 ± 0.028
2.269TyrAsp: 2.269 ± 0.069
2.284TyrGlu: 2.284 ± 0.071
1.435TyrPhe: 1.435 ± 0.054
2.779TyrGly: 2.779 ± 0.084
0.827TyrHis: 0.827 ± 0.042
2.022TyrIle: 2.022 ± 0.057
1.122TyrLys: 1.122 ± 0.049
3.073TyrLeu: 3.073 ± 0.077
0.789TyrMet: 0.789 ± 0.035
1.136TyrAsn: 1.136 ± 0.046
1.328TyrPro: 1.328 ± 0.049
1.048TyrGln: 1.048 ± 0.038
2.164TyrArg: 2.164 ± 0.064
1.468TyrSer: 1.468 ± 0.049
2.012TyrThr: 2.012 ± 0.068
2.109TyrVal: 2.109 ± 0.053
0.339TyrTrp: 0.339 ± 0.028
1.171TyrTyr: 1.171 ± 0.041
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2020 proteins (628603 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski