Amino acid dipepetide frequency for Rhizophagus clarus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	2.833AlaAla: 2.833 ± 0.029	0.661AlaCys: 0.661 ± 0.009	2.337AlaAsp: 2.337 ± 0.016	2.883AlaGlu: 2.883 ± 0.026	2.294AlaPhe: 2.294 ± 0.029	1.835AlaGly: 1.835 ± 0.018	1.062AlaHis: 1.062 ± 0.011	3.765AlaIle: 3.765 ± 0.022	3.425AlaLys: 3.425 ± 0.022	4.095AlaLeu: 4.095 ± 0.022	1.026AlaMet: 1.026 ± 0.017	2.781AlaAsn: 2.781 ± 0.02	1.744AlaPro: 1.744 ± 0.02	1.751AlaGln: 1.751 ± 0.019	1.911AlaArg: 1.911 ± 0.015	3.421AlaSer: 3.421 ± 0.022	2.515AlaThr: 2.515 ± 0.018	2.183AlaVal: 2.183 ± 0.016	0.411AlaTrp: 0.411 ± 0.006	1.552AlaTyr: 1.552 ± 0.015	0.003AlaXaa: 0.003 ± 0.001
Cys	0.596CysAla: 0.596 ± 0.009	0.331CysCys: 0.331 ± 0.007	0.931CysAsp: 0.931 ± 0.009	1.02CysGlu: 1.02 ± 0.011	0.731CysPhe: 0.731 ± 0.009	0.962CysGly: 0.962 ± 0.014	0.422CysHis: 0.422 ± 0.006	1.119CysIle: 1.119 ± 0.011	1.298CysLys: 1.298 ± 0.014	1.612CysLeu: 1.612 ± 0.015	0.274CysMet: 0.274 ± 0.005	1.116CysAsn: 1.116 ± 0.013	0.641CysPro: 0.641 ± 0.009	0.709CysGln: 0.709 ± 0.009	0.7CysArg: 0.7 ± 0.009	1.117CysSer: 1.117 ± 0.01	0.693CysThr: 0.693 ± 0.009	0.647CysVal: 0.647 ± 0.008	0.339CysTrp: 0.339 ± 0.006	1.076CysTyr: 1.076 ± 0.023	0.002CysXaa: 0.002 ± 0.0
Asp	2.343AspAla: 2.343 ± 0.018	0.801AspCys: 0.801 ± 0.01	4.83AspAsp: 4.83 ± 0.042	4.637AspGlu: 4.637 ± 0.025	2.907AspPhe: 2.907 ± 0.018	2.648AspGly: 2.648 ± 0.018	1.184AspHis: 1.184 ± 0.012	5.08AspIle: 5.08 ± 0.022	4.24AspLys: 4.24 ± 0.026	5.361AspLeu: 5.361 ± 0.027	1.073AspMet: 1.073 ± 0.01	4.233AspAsn: 4.233 ± 0.021	2.241AspPro: 2.241 ± 0.018	1.909AspGln: 1.909 ± 0.016	2.04AspArg: 2.04 ± 0.019	4.117AspSer: 4.117 ± 0.022	2.686AspThr: 2.686 ± 0.018	2.865AspVal: 2.865 ± 0.019	0.744AspTrp: 0.744 ± 0.009	2.596AspTyr: 2.596 ± 0.021	0.005AspXaa: 0.005 ± 0.001
Glu	2.809GluAla: 2.809 ± 0.019	0.984GluCys: 0.984 ± 0.011	3.743GluAsp: 3.743 ± 0.026	5.768GluGlu: 5.768 ± 0.035	3.193GluPhe: 3.193 ± 0.02	2.426GluGly: 2.426 ± 0.021	1.214GluHis: 1.214 ± 0.01	6.385GluIle: 6.385 ± 0.032	6.325GluLys: 6.325 ± 0.044	6.46GluLeu: 6.46 ± 0.031	1.408GluMet: 1.408 ± 0.011	5.369GluAsn: 5.369 ± 0.03	1.77GluPro: 1.77 ± 0.016	2.41GluGln: 2.41 ± 0.018	2.97GluArg: 2.97 ± 0.024	4.339GluSer: 4.339 ± 0.024	3.221GluThr: 3.221 ± 0.021	3.419GluVal: 3.419 ± 0.022	1.112GluTrp: 1.112 ± 0.014	2.849GluTyr: 2.849 ± 0.02	0.005GluXaa: 0.005 ± 0.001
Phe	1.905PheAla: 1.905 ± 0.012	0.805PheCys: 0.805 ± 0.009	2.704PheAsp: 2.704 ± 0.018	3.169PheGlu: 3.169 ± 0.024	2.007PhePhe: 2.007 ± 0.018	2.472PheGly: 2.472 ± 0.021	1.189PheHis: 1.189 ± 0.013	3.821PheIle: 3.821 ± 0.025	3.376PheLys: 3.376 ± 0.021	4.094PheLeu: 4.094 ± 0.025	0.893PheMet: 0.893 ± 0.01	3.34PheAsn: 3.34 ± 0.02	1.65PhePro: 1.65 ± 0.014	1.753PheGln: 1.753 ± 0.013	1.783PheArg: 1.783 ± 0.015	3.732PheSer: 3.732 ± 0.023	2.431PheThr: 2.431 ± 0.016	2.223PheVal: 2.223 ± 0.016	0.532PheTrp: 0.532 ± 0.008	2.036PheTyr: 2.036 ± 0.021	0.004PheXaa: 0.004 ± 0.001
Gly	1.712GlyAla: 1.712 ± 0.015	0.767GlyCys: 0.767 ± 0.01	2.191GlyAsp: 2.191 ± 0.018	2.502GlyGlu: 2.502 ± 0.021	2.083GlyPhe: 2.083 ± 0.019	2.692GlyGly: 2.692 ± 0.033	1.013GlyHis: 1.013 ± 0.012	4.095GlyIle: 4.095 ± 0.028	3.411GlyLys: 3.411 ± 0.024	3.694GlyLeu: 3.694 ± 0.021	0.828GlyMet: 0.828 ± 0.01	3.198GlyAsn: 3.198 ± 0.023	1.402GlyPro: 1.402 ± 0.017	1.367GlyGln: 1.367 ± 0.014	1.958GlyArg: 1.958 ± 0.017	3.13GlySer: 3.13 ± 0.02	2.508GlyThr: 2.508 ± 0.021	2.316GlyVal: 2.316 ± 0.019	0.552GlyTrp: 0.552 ± 0.007	2.006GlyTyr: 2.006 ± 0.02	0.003GlyXaa: 0.003 ± 0.001
His	0.96HisAla: 0.96 ± 0.01	0.386HisCys: 0.386 ± 0.007	1.4HisAsp: 1.4 ± 0.013	1.308HisGlu: 1.308 ± 0.012	1.071HisPhe: 1.071 ± 0.011	0.931HisGly: 0.931 ± 0.011	0.72HisHis: 0.72 ± 0.013	1.756HisIle: 1.756 ± 0.015	1.466HisLys: 1.466 ± 0.012	2.234HisLeu: 2.234 ± 0.015	0.404HisMet: 0.404 ± 0.007	1.538HisAsn: 1.538 ± 0.013	1.022HisPro: 1.022 ± 0.012	0.976HisGln: 0.976 ± 0.011	0.99HisArg: 0.99 ± 0.01	1.744HisSer: 1.744 ± 0.015	1.077HisThr: 1.077 ± 0.011	1.102HisVal: 1.102 ± 0.012	0.307HisTrp: 0.307 ± 0.008	0.943HisTyr: 0.943 ± 0.01	0.002HisXaa: 0.002 ± 0.0
Ile	3.431IleAla: 3.431 ± 0.02	1.431IleCys: 1.431 ± 0.013	4.838IleAsp: 4.838 ± 0.027	5.317IleGlu: 5.317 ± 0.026	3.591IlePhe: 3.591 ± 0.019	3.38IleGly: 3.38 ± 0.023	1.85IleHis: 1.85 ± 0.013	6.89IleIle: 6.89 ± 0.038	6.47IleLys: 6.47 ± 0.03	7.48IleLeu: 7.48 ± 0.029	1.613IleMet: 1.613 ± 0.013	5.779IleAsn: 5.779 ± 0.034	3.817IlePro: 3.817 ± 0.022	3.062IleGln: 3.062 ± 0.018	3.317IleArg: 3.317 ± 0.019	6.628IleSer: 6.628 ± 0.025	4.585IleThr: 4.585 ± 0.024	3.772IleVal: 3.772 ± 0.021	0.926IleTrp: 0.926 ± 0.01	3.467IleTyr: 3.467 ± 0.022	0.008IleXaa: 0.008 ± 0.001
Lys	4.121LysAla: 4.121 ± 0.045	1.438LysCys: 1.438 ± 0.017	4.589LysAsp: 4.589 ± 0.025	6.135LysGlu: 6.135 ± 0.034	3.455LysPhe: 3.455 ± 0.021	3.032LysGly: 3.032 ± 0.025	1.633LysHis: 1.633 ± 0.013	6.399LysIle: 6.399 ± 0.031	7.524LysLys: 7.524 ± 0.04	7.259LysLeu: 7.259 ± 0.03	1.47LysMet: 1.47 ± 0.012	5.933LysAsn: 5.933 ± 0.038	2.543LysPro: 2.543 ± 0.019	2.83LysGln: 2.83 ± 0.021	3.982LysArg: 3.982 ± 0.019	5.798LysSer: 5.798 ± 0.028	3.533LysThr: 3.533 ± 0.022	3.835LysVal: 3.835 ± 0.022	1.086LysTrp: 1.086 ± 0.011	3.423LysTyr: 3.423 ± 0.024	0.007LysXaa: 0.007 ± 0.001
Leu	4.451LeuAla: 4.451 ± 0.028	1.541LeuCys: 1.541 ± 0.013	4.853LeuAsp: 4.853 ± 0.025	6.359LeuGlu: 6.359 ± 0.035	4.013LeuPhe: 4.013 ± 0.027	3.921LeuGly: 3.921 ± 0.029	2.174LeuHis: 2.174 ± 0.016	6.798LeuIle: 6.798 ± 0.032	7.765LeuLys: 7.765 ± 0.038	8.238LeuLeu: 8.238 ± 0.041	1.728LeuMet: 1.728 ± 0.013	6.083LeuAsn: 6.083 ± 0.029	4.161LeuPro: 4.161 ± 0.025	3.709LeuGln: 3.709 ± 0.024	4.303LeuArg: 4.303 ± 0.023	7.555LeuSer: 7.555 ± 0.033	4.67LeuThr: 4.67 ± 0.026	4.19LeuVal: 4.19 ± 0.023	1.07LeuTrp: 1.07 ± 0.012	3.596LeuTyr: 3.596 ± 0.023	0.007LeuXaa: 0.007 ± 0.001
Met	1.066MetAla: 1.066 ± 0.011	0.238MetCys: 0.238 ± 0.005	1.186MetAsp: 1.186 ± 0.01	1.365MetGlu: 1.365 ± 0.013	0.774MetPhe: 0.774 ± 0.01	0.765MetGly: 0.765 ± 0.01	0.404MetHis: 0.404 ± 0.007	1.526MetIle: 1.526 ± 0.012	1.572MetLys: 1.572 ± 0.015	1.542MetLeu: 1.542 ± 0.013	0.46MetMet: 0.46 ± 0.008	1.335MetAsn: 1.335 ± 0.014	0.687MetPro: 0.687 ± 0.008	0.693MetGln: 0.693 ± 0.01	0.772MetArg: 0.772 ± 0.009	1.591MetSer: 1.591 ± 0.013	1.103MetThr: 1.103 ± 0.01	1.056MetVal: 1.056 ± 0.012	0.223MetTrp: 0.223 ± 0.004	0.647MetTyr: 0.647 ± 0.009	0.003MetXaa: 0.003 ± 0.001
Asn	2.707AsnAla: 2.707 ± 0.019	1.093AsnCys: 1.093 ± 0.012	4.609AsnAsp: 4.609 ± 0.03	5.151AsnGlu: 5.151 ± 0.032	3.391AsnPhe: 3.391 ± 0.019	3.254AsnGly: 3.254 ± 0.029	1.488AsnHis: 1.488 ± 0.012	6.384AsnIle: 6.384 ± 0.032	5.457AsnLys: 5.457 ± 0.034	6.741AsnLeu: 6.741 ± 0.04	1.311AsnMet: 1.311 ± 0.014	7.0AsnAsn: 7.0 ± 0.05	2.709AsnPro: 2.709 ± 0.02	2.632AsnGln: 2.632 ± 0.021	2.537AsnArg: 2.537 ± 0.016	5.726AsnSer: 5.726 ± 0.029	3.622AsnThr: 3.622 ± 0.021	3.372AsnVal: 3.372 ± 0.019	0.992AsnTrp: 0.992 ± 0.015	3.051AsnTyr: 3.051 ± 0.021	0.005AsnXaa: 0.005 ± 0.001
Pro	1.734ProAla: 1.734 ± 0.019	0.474ProCys: 0.474 ± 0.008	2.313ProAsp: 2.313 ± 0.018	2.729ProGlu: 2.729 ± 0.017	1.877ProPhe: 1.877 ± 0.014	1.547ProGly: 1.547 ± 0.02	0.835ProHis: 0.835 ± 0.01	3.065ProIle: 3.065 ± 0.02	2.89ProLys: 2.89 ± 0.023	3.428ProLeu: 3.428 ± 0.022	0.604ProMet: 0.604 ± 0.008	2.798ProAsn: 2.798 ± 0.02	2.59ProPro: 2.59 ± 0.029	1.57ProGln: 1.57 ± 0.021	1.508ProArg: 1.508 ± 0.014	3.677ProSer: 3.677 ± 0.028	2.528ProThr: 2.528 ± 0.02	2.037ProVal: 2.037 ± 0.016	0.344ProTrp: 0.344 ± 0.007	1.784ProTyr: 1.784 ± 0.016	0.004ProXaa: 0.004 ± 0.001
Gln	1.664GlnAla: 1.664 ± 0.017	0.556GlnCys: 0.556 ± 0.008	2.028GlnAsp: 2.028 ± 0.014	2.643GlnGlu: 2.643 ± 0.019	1.651GlnPhe: 1.651 ± 0.014	1.307GlnGly: 1.307 ± 0.012	1.008GlnHis: 1.008 ± 0.012	2.976GlnIle: 2.976 ± 0.017	3.224GlnLys: 3.224 ± 0.026	3.56GlnLeu: 3.56 ± 0.022	0.75GlnMet: 0.75 ± 0.008	3.129GlnAsn: 3.129 ± 0.025	1.564GlnPro: 1.564 ± 0.021	2.383GlnGln: 2.383 ± 0.033	1.699GlnArg: 1.699 ± 0.016	2.66GlnSer: 2.66 ± 0.023	1.913GlnThr: 1.913 ± 0.015	1.73GlnVal: 1.73 ± 0.014	0.395GlnTrp: 0.395 ± 0.007	1.513GlnTyr: 1.513 ± 0.017	0.004GlnXaa: 0.004 ± 0.001
Arg	1.913ArgAla: 1.913 ± 0.016	0.71ArgCys: 0.71 ± 0.009	2.391ArgAsp: 2.391 ± 0.021	2.759ArgGlu: 2.759 ± 0.022	1.893ArgPhe: 1.893 ± 0.014	1.797ArgGly: 1.797 ± 0.018	0.978ArgHis: 0.978 ± 0.011	3.313ArgIle: 3.313 ± 0.02	3.802ArgLys: 3.802 ± 0.021	3.904ArgLeu: 3.904 ± 0.025	0.84ArgMet: 0.84 ± 0.009	2.994ArgAsn: 2.994 ± 0.016	1.899ArgPro: 1.899 ± 0.015	1.644ArgGln: 1.644 ± 0.016	2.491ArgArg: 2.491 ± 0.022	3.217ArgSer: 3.217 ± 0.023	2.112ArgThr: 2.112 ± 0.016	2.03ArgVal: 2.03 ± 0.016	0.537ArgTrp: 0.537 ± 0.007	1.626ArgTyr: 1.626 ± 0.014	0.003ArgXaa: 0.003 ± 0.001
Ser	3.43SerAla: 3.43 ± 0.022	1.181SerCys: 1.181 ± 0.012	4.568SerAsp: 4.568 ± 0.025	4.668SerGlu: 4.668 ± 0.029	3.81SerPhe: 3.81 ± 0.02	3.499SerGly: 3.499 ± 0.022	1.758SerHis: 1.758 ± 0.016	5.824SerIle: 5.824 ± 0.028	5.789SerLys: 5.789 ± 0.024	7.373SerLeu: 7.373 ± 0.039	1.361SerMet: 1.361 ± 0.012	5.619SerAsn: 5.619 ± 0.026	3.425SerPro: 3.425 ± 0.029	3.289SerGln: 3.289 ± 0.022	3.439SerArg: 3.439 ± 0.023	8.45SerSer: 8.45 ± 0.059	4.689SerThr: 4.689 ± 0.029	3.426SerVal: 3.426 ± 0.018	0.838SerTrp: 0.838 ± 0.01	2.787SerTyr: 2.787 ± 0.017	0.008SerXaa: 0.008 ± 0.001
Thr	2.371ThrAla: 2.371 ± 0.019	0.821ThrCys: 0.821 ± 0.01	2.701ThrAsp: 2.701 ± 0.016	3.101ThrGlu: 3.101 ± 0.023	2.485ThrPhe: 2.485 ± 0.019	2.294ThrGly: 2.294 ± 0.017	1.096ThrHis: 1.096 ± 0.011	4.195ThrIle: 4.195 ± 0.024	3.968ThrLys: 3.968 ± 0.024	4.908ThrLeu: 4.908 ± 0.025	0.909ThrMet: 0.909 ± 0.009	3.647ThrAsn: 3.647 ± 0.024	2.816ThrPro: 2.816 ± 0.024	1.877ThrGln: 1.877 ± 0.018	2.207ThrArg: 2.207 ± 0.017	5.043ThrSer: 5.043 ± 0.026	3.522ThrThr: 3.522 ± 0.031	2.517ThrVal: 2.517 ± 0.016	0.609ThrTrp: 0.609 ± 0.008	1.853ThrTyr: 1.853 ± 0.013	0.005ThrXaa: 0.005 ± 0.001
Val	2.44ValAla: 2.44 ± 0.018	0.742ValCys: 0.742 ± 0.009	2.923ValAsp: 2.923 ± 0.019	3.145ValGlu: 3.145 ± 0.02	2.103ValPhe: 2.103 ± 0.017	2.059ValGly: 2.059 ± 0.017	1.074ValHis: 1.074 ± 0.011	3.914ValIle: 3.914 ± 0.02	3.811ValLys: 3.811 ± 0.019	4.373ValLeu: 4.373 ± 0.021	0.979ValMet: 0.979 ± 0.009	3.209ValAsn: 3.209 ± 0.018	2.011ValPro: 2.011 ± 0.017	1.697ValGln: 1.697 ± 0.015	2.033ValArg: 2.033 ± 0.015	3.436ValSer: 3.436 ± 0.024	2.76ValThr: 2.76 ± 0.019	2.666ValVal: 2.666 ± 0.02	0.532ValTrp: 0.532 ± 0.007	1.908ValTyr: 1.908 ± 0.015	0.005ValXaa: 0.005 ± 0.001
Trp	0.475TrpAla: 0.475 ± 0.007	0.401TrpCys: 0.401 ± 0.009	0.806TrpAsp: 0.806 ± 0.008	0.804TrpGlu: 0.804 ± 0.01	0.527TrpPhe: 0.527 ± 0.007	0.456TrpGly: 0.456 ± 0.007	0.246TrpHis: 0.246 ± 0.005	1.22TrpIle: 1.22 ± 0.015	1.191TrpLys: 1.191 ± 0.014	0.881TrpLeu: 0.881 ± 0.012	0.273TrpMet: 0.273 ± 0.005	0.97TrpAsn: 0.97 ± 0.009	0.313TrpPro: 0.313 ± 0.006	0.349TrpGln: 0.349 ± 0.006	0.512TrpArg: 0.512 ± 0.007	0.82TrpSer: 0.82 ± 0.009	0.735TrpThr: 0.735 ± 0.01	0.563TrpVal: 0.563 ± 0.007	0.157TrpTrp: 0.157 ± 0.004	0.683TrpTyr: 0.683 ± 0.018	0.001TrpXaa: 0.001 ± 0.0
Tyr	1.522TyrAla: 1.522 ± 0.011	0.971TyrCys: 0.971 ± 0.013	2.596TyrAsp: 2.596 ± 0.018	2.707TyrGlu: 2.707 ± 0.022	2.059TyrPhe: 2.059 ± 0.017	2.15TyrGly: 2.15 ± 0.018	0.988TyrHis: 0.988 ± 0.01	3.122TyrIle: 3.122 ± 0.023	3.012TyrLys: 3.012 ± 0.025	3.942TyrLeu: 3.942 ± 0.022	0.801TyrMet: 0.801 ± 0.01	3.153TyrAsn: 3.153 ± 0.026	1.327TyrPro: 1.327 ± 0.013	1.744TyrGln: 1.744 ± 0.017	1.699TyrArg: 1.699 ± 0.016	3.027TyrSer: 3.027 ± 0.019	2.039TyrThr: 2.039 ± 0.014	1.866TyrVal: 1.866 ± 0.014	0.673TyrTrp: 0.673 ± 0.016	2.176TyrTyr: 2.176 ± 0.023	0.003TyrXaa: 0.003 ± 0.001
Xaa	0.004XaaAla: 0.004 ± 0.001	0.002XaaCys: 0.002 ± 0.0	0.004XaaAsp: 0.004 ± 0.001	0.007XaaGlu: 0.007 ± 0.001	0.006XaaPhe: 0.006 ± 0.001	0.004XaaGly: 0.004 ± 0.001	0.002XaaHis: 0.002 ± 0.0	0.006XaaIle: 0.006 ± 0.001	0.008XaaLys: 0.008 ± 0.001	0.007XaaLeu: 0.007 ± 0.001	0.002XaaMet: 0.002 ± 0.0	0.007XaaAsn: 0.007 ± 0.001	0.003XaaPro: 0.003 ± 0.001	0.004XaaGln: 0.004 ± 0.001	0.004XaaArg: 0.004 ± 0.001	0.005XaaSer: 0.005 ± 0.001	0.004XaaThr: 0.004 ± 0.001	0.004XaaVal: 0.004 ± 0.001	0.001XaaTrp: 0.001 ± 0.0	0.004XaaTyr: 0.004 ± 0.001	0.087XaaXaa: 0.087 ± 0.006

Statistics based on 27461 proteins (10447393 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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