Amino acid dipepetide frequency for Beet chlorosis virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.345AlaAla: 2.345 ± 0.986
0.469AlaCys: 0.469 ± 0.286
2.345AlaAsp: 2.345 ± 0.935
3.283AlaGlu: 3.283 ± 0.57
1.407AlaPhe: 1.407 ± 1.327
3.283AlaGly: 3.283 ± 1.886
0.0AlaHis: 0.0 ± 0.0
4.69AlaIle: 4.69 ± 0.73
3.752AlaLys: 3.752 ± 0.51
4.221AlaLeu: 4.221 ± 0.994
1.876AlaMet: 1.876 ± 0.652
0.0AlaAsn: 0.0 ± 0.0
2.814AlaPro: 2.814 ± 1.719
2.814AlaGln: 2.814 ± 0.651
4.221AlaArg: 4.221 ± 1.644
6.098AlaSer: 6.098 ± 1.442
1.876AlaThr: 1.876 ± 0.494
4.221AlaVal: 4.221 ± 1.604
0.469AlaTrp: 0.469 ± 0.519
3.752AlaTyr: 3.752 ± 1.064
0.0AlaXaa: 0.0 ± 0.0
Cys
0.938CysAla: 0.938 ± 0.573
0.469CysCys: 0.469 ± 0.286
1.407CysAsp: 1.407 ± 0.859
0.0CysGlu: 0.0 ± 0.0
0.938CysPhe: 0.938 ± 0.566
0.938CysGly: 0.938 ± 0.573
1.876CysHis: 1.876 ± 0.901
0.938CysIle: 0.938 ± 0.573
0.938CysLys: 0.938 ± 0.632
1.876CysLeu: 1.876 ± 0.765
0.0CysMet: 0.0 ± 0.0
0.938CysAsn: 0.938 ± 1.332
0.938CysPro: 0.938 ± 0.632
0.469CysGln: 0.469 ± 0.666
0.0CysArg: 0.0 ± 0.0
2.345CysSer: 2.345 ± 1.103
0.469CysThr: 0.469 ± 0.286
0.938CysVal: 0.938 ± 0.566
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.814AspAla: 2.814 ± 0.918
1.407AspCys: 1.407 ± 0.664
6.567AspAsp: 6.567 ± 2.264
4.221AspGlu: 4.221 ± 2.655
2.814AspPhe: 2.814 ± 1.272
4.221AspGly: 4.221 ± 1.75
0.938AspHis: 0.938 ± 0.938
1.407AspIle: 1.407 ± 0.562
2.345AspLys: 2.345 ± 1.381
3.752AspLeu: 3.752 ± 1.722
1.876AspMet: 1.876 ± 1.368
2.814AspAsn: 2.814 ± 0.704
2.345AspPro: 2.345 ± 0.756
1.407AspGln: 1.407 ± 0.664
1.876AspArg: 1.876 ± 0.494
3.752AspSer: 3.752 ± 1.53
1.876AspThr: 1.876 ± 1.146
3.283AspVal: 3.283 ± 1.194
1.876AspTrp: 1.876 ± 1.146
0.469AspTyr: 0.469 ± 0.286
0.0AspXaa: 0.0 ± 0.0
Glu
3.283GluAla: 3.283 ± 0.962
1.407GluCys: 1.407 ± 0.718
4.69GluAsp: 4.69 ± 1.422
5.629GluGlu: 5.629 ± 2.207
1.876GluPhe: 1.876 ± 0.901
3.752GluGly: 3.752 ± 1.151
0.469GluHis: 0.469 ± 0.687
3.283GluIle: 3.283 ± 1.494
3.752GluLys: 3.752 ± 1.664
6.098GluLeu: 6.098 ± 0.492
0.469GluMet: 0.469 ± 0.286
0.469GluAsn: 0.469 ± 0.519
1.876GluPro: 1.876 ± 0.752
2.814GluGln: 2.814 ± 1.633
6.098GluArg: 6.098 ± 1.71
4.221GluSer: 4.221 ± 1.485
2.814GluThr: 2.814 ± 0.537
3.752GluVal: 3.752 ± 1.771
0.938GluTrp: 0.938 ± 0.774
3.752GluTyr: 3.752 ± 0.708
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.938PheCys: 0.938 ± 0.573
0.469PheAsp: 0.469 ± 0.286
3.752PheGlu: 3.752 ± 1.219
2.345PhePhe: 2.345 ± 1.009
4.69PheGly: 4.69 ± 2.018
0.938PheHis: 0.938 ± 0.632
2.345PheIle: 2.345 ± 1.417
2.814PheLys: 2.814 ± 1.202
2.814PheLeu: 2.814 ± 1.12
0.0PheMet: 0.0 ± 0.0
2.345PheAsn: 2.345 ± 0.986
0.938PhePro: 0.938 ± 0.642
0.938PheGln: 0.938 ± 0.566
1.876PheArg: 1.876 ± 1.684
2.814PheSer: 2.814 ± 1.618
2.345PheThr: 2.345 ± 0.654
1.876PheVal: 1.876 ± 1.264
0.469PheTrp: 0.469 ± 0.687
0.469PheTyr: 0.469 ± 0.286
0.0PheXaa: 0.0 ± 0.0
Gly
3.283GlyAla: 3.283 ± 0.962
1.407GlyCys: 1.407 ± 0.601
3.283GlyAsp: 3.283 ± 1.046
2.345GlyGlu: 2.345 ± 0.743
3.752GlyPhe: 3.752 ± 1.74
2.814GlyGly: 2.814 ± 1.458
1.876GlyHis: 1.876 ± 0.952
1.876GlyIle: 1.876 ± 0.487
3.283GlyLys: 3.283 ± 1.129
6.567GlyLeu: 6.567 ± 2.49
1.876GlyMet: 1.876 ± 0.861
3.283GlyAsn: 3.283 ± 1.032
3.283GlyPro: 3.283 ± 0.559
2.814GlyGln: 2.814 ± 0.651
5.629GlyArg: 5.629 ± 3.401
8.443GlySer: 8.443 ± 2.317
3.752GlyThr: 3.752 ± 1.712
2.814GlyVal: 2.814 ± 1.272
2.345GlyTrp: 2.345 ± 1.009
4.221GlyTyr: 4.221 ± 1.471
0.0GlyXaa: 0.0 ± 0.0
His
1.407HisAla: 1.407 ± 0.859
0.938HisCys: 0.938 ± 0.632
3.283HisAsp: 3.283 ± 1.358
0.938HisGlu: 0.938 ± 1.072
1.407HisPhe: 1.407 ± 1.096
0.938HisGly: 0.938 ± 0.566
0.938HisHis: 0.938 ± 1.332
0.938HisIle: 0.938 ± 0.459
0.469HisLys: 0.469 ± 0.286
2.345HisLeu: 2.345 ± 1.182
0.0HisMet: 0.0 ± 0.0
1.407HisAsn: 1.407 ± 0.94
1.407HisPro: 1.407 ± 0.587
0.469HisGln: 0.469 ± 0.666
1.876HisArg: 1.876 ± 0.716
2.814HisSer: 2.814 ± 0.918
2.345HisThr: 2.345 ± 0.758
0.469HisVal: 0.469 ± 0.286
0.938HisTrp: 0.938 ± 0.459
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.814IleAla: 2.814 ± 1.616
0.469IleCys: 0.469 ± 0.666
1.876IleAsp: 1.876 ± 1.168
3.752IleGlu: 3.752 ± 0.964
0.469IlePhe: 0.469 ± 0.286
2.814IleGly: 2.814 ± 1.275
1.407IleHis: 1.407 ± 0.601
1.876IleIle: 1.876 ± 1.132
3.752IleLys: 3.752 ± 1.085
6.098IleLeu: 6.098 ± 2.292
0.469IleMet: 0.469 ± 0.286
3.752IleAsn: 3.752 ± 2.352
3.283IlePro: 3.283 ± 0.823
0.0IleGln: 0.0 ± 0.0
2.345IleArg: 2.345 ± 1.009
6.567IleSer: 6.567 ± 1.739
4.221IleThr: 4.221 ± 1.942
3.283IleVal: 3.283 ± 1.312
0.938IleTrp: 0.938 ± 0.566
0.938IleTyr: 0.938 ± 0.573
0.0IleXaa: 0.0 ± 0.0
Lys
5.629LysAla: 5.629 ± 1.817
0.938LysCys: 0.938 ± 0.632
2.345LysAsp: 2.345 ± 1.05
4.69LysGlu: 4.69 ± 1.32
2.345LysPhe: 2.345 ± 1.009
2.814LysGly: 2.814 ± 0.729
2.345LysHis: 2.345 ± 0.743
3.752LysIle: 3.752 ± 1.314
1.407LysLys: 1.407 ± 0.859
5.629LysLeu: 5.629 ± 1.647
1.876LysMet: 1.876 ± 0.77
2.345LysAsn: 2.345 ± 1.432
3.283LysPro: 3.283 ± 1.374
1.876LysGln: 1.876 ± 0.918
4.69LysArg: 4.69 ± 1.632
4.221LysSer: 4.221 ± 1.374
3.283LysThr: 3.283 ± 1.242
1.876LysVal: 1.876 ± 0.885
0.469LysTrp: 0.469 ± 0.286
1.876LysTyr: 1.876 ± 0.952
0.0LysXaa: 0.0 ± 0.0
Leu
5.159LeuAla: 5.159 ± 0.819
1.876LeuCys: 1.876 ± 0.752
3.752LeuAsp: 3.752 ± 1.223
6.567LeuGlu: 6.567 ± 1.734
4.221LeuPhe: 4.221 ± 1.508
2.814LeuGly: 2.814 ± 1.12
2.345LeuHis: 2.345 ± 1.182
5.159LeuIle: 5.159 ± 1.634
7.036LeuLys: 7.036 ± 3.347
4.69LeuLeu: 4.69 ± 2.264
2.345LeuMet: 2.345 ± 1.103
3.283LeuAsn: 3.283 ± 0.962
7.974LeuPro: 7.974 ± 1.675
5.629LeuGln: 5.629 ± 1.877
3.752LeuArg: 3.752 ± 2.191
5.629LeuSer: 5.629 ± 2.074
7.974LeuThr: 7.974 ± 1.368
5.159LeuVal: 5.159 ± 2.035
1.876LeuTrp: 1.876 ± 0.885
3.283LeuTyr: 3.283 ± 0.614
0.0LeuXaa: 0.0 ± 0.0
Met
3.283MetAla: 3.283 ± 1.312
0.0MetCys: 0.0 ± 0.0
1.407MetAsp: 1.407 ± 0.859
3.283MetGlu: 3.283 ± 1.301
0.0MetPhe: 0.0 ± 0.0
1.876MetGly: 1.876 ± 0.752
0.0MetHis: 0.0 ± 0.0
0.938MetIle: 0.938 ± 1.038
0.938MetLys: 0.938 ± 0.573
1.876MetLeu: 1.876 ± 0.805
0.0MetMet: 0.0 ± 0.0
2.345MetAsn: 2.345 ± 1.05
0.938MetPro: 0.938 ± 0.78
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.876MetSer: 1.876 ± 0.885
0.938MetThr: 0.938 ± 0.815
2.814MetVal: 2.814 ± 0.87
0.469MetTrp: 0.469 ± 0.286
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.814AsnAla: 2.814 ± 0.918
0.0AsnCys: 0.0 ± 0.0
1.407AsnAsp: 1.407 ± 0.937
0.938AsnGlu: 0.938 ± 0.573
0.938AsnPhe: 0.938 ± 0.78
3.752AsnGly: 3.752 ± 2.982
0.469AsnHis: 0.469 ± 0.286
0.938AsnIle: 0.938 ± 0.566
3.283AsnLys: 3.283 ± 0.765
4.221AsnLeu: 4.221 ± 0.907
0.938AsnMet: 0.938 ± 0.465
3.752AsnAsn: 3.752 ± 0.915
2.345AsnPro: 2.345 ± 1.351
1.876AsnGln: 1.876 ± 0.487
2.814AsnArg: 2.814 ± 0.95
6.567AsnSer: 6.567 ± 0.767
2.814AsnThr: 2.814 ± 1.227
3.752AsnVal: 3.752 ± 1.538
1.407AsnTrp: 1.407 ± 0.562
0.938AsnTyr: 0.938 ± 0.459
0.0AsnXaa: 0.0 ± 0.0
Pro
2.345ProAla: 2.345 ± 1.067
0.0ProCys: 0.0 ± 0.0
2.814ProAsp: 2.814 ± 1.874
1.876ProGlu: 1.876 ± 1.261
1.407ProPhe: 1.407 ± 0.983
4.221ProGly: 4.221 ± 1.056
1.876ProHis: 1.876 ± 0.859
1.876ProIle: 1.876 ± 1.146
5.629ProLys: 5.629 ± 1.314
3.752ProLeu: 3.752 ± 1.029
0.938ProMet: 0.938 ± 0.459
2.345ProAsn: 2.345 ± 0.555
2.814ProPro: 2.814 ± 1.272
4.69ProGln: 4.69 ± 0.977
1.876ProArg: 1.876 ± 1.549
3.752ProSer: 3.752 ± 0.505
4.221ProThr: 4.221 ± 1.505
3.283ProVal: 3.283 ± 0.734
0.469ProTrp: 0.469 ± 0.519
0.938ProTyr: 0.938 ± 0.573
0.0ProXaa: 0.0 ± 0.0
Gln
2.345GlnAla: 2.345 ± 1.009
0.469GlnCys: 0.469 ± 0.519
1.407GlnAsp: 1.407 ± 0.937
2.814GlnGlu: 2.814 ± 0.918
0.938GlnPhe: 0.938 ± 1.108
1.876GlnGly: 1.876 ± 1.444
0.938GlnHis: 0.938 ± 0.642
1.407GlnIle: 1.407 ± 0.601
2.814GlnLys: 2.814 ± 1.272
7.974GlnLeu: 7.974 ± 2.481
0.0GlnMet: 0.0 ± 0.0
2.345GlnAsn: 2.345 ± 0.555
1.876GlnPro: 1.876 ± 0.901
1.407GlnGln: 1.407 ± 1.557
5.159GlnArg: 5.159 ± 1.302
2.814GlnSer: 2.814 ± 1.507
1.407GlnThr: 1.407 ± 1.694
0.938GlnVal: 0.938 ± 0.938
0.469GlnTrp: 0.469 ± 0.687
0.469GlnTyr: 0.469 ± 0.286
0.0GlnXaa: 0.0 ± 0.0
Arg
4.69ArgAla: 4.69 ± 2.657
0.469ArgCys: 0.469 ± 0.286
2.345ArgAsp: 2.345 ± 1.381
3.283ArgGlu: 3.283 ± 0.57
2.345ArgPhe: 2.345 ± 1.029
2.345ArgGly: 2.345 ± 1.265
2.345ArgHis: 2.345 ± 1.182
2.345ArgIle: 2.345 ± 1.471
2.345ArgLys: 2.345 ± 1.022
8.443ArgLeu: 8.443 ± 2.797
1.876ArgMet: 1.876 ± 0.598
1.876ArgAsn: 1.876 ± 0.885
4.69ArgPro: 4.69 ± 1.314
1.876ArgGln: 1.876 ± 0.901
7.505ArgArg: 7.505 ± 8.163
3.752ArgSer: 3.752 ± 1.285
4.221ArgThr: 4.221 ± 2.057
4.69ArgVal: 4.69 ± 0.973
1.876ArgTrp: 1.876 ± 0.652
0.938ArgTyr: 0.938 ± 0.459
0.0ArgXaa: 0.0 ± 0.0
Ser
2.814SerAla: 2.814 ± 0.927
1.407SerCys: 1.407 ± 0.562
3.283SerAsp: 3.283 ± 0.962
5.629SerGlu: 5.629 ± 2.567
2.814SerPhe: 2.814 ± 0.81
9.85SerGly: 9.85 ± 1.623
2.345SerHis: 2.345 ± 1.432
5.629SerIle: 5.629 ± 1.836
3.752SerLys: 3.752 ± 1.31
9.381SerLeu: 9.381 ± 0.343
2.814SerMet: 2.814 ± 1.838
2.814SerAsn: 2.814 ± 0.729
1.407SerPro: 1.407 ± 1.299
3.283SerGln: 3.283 ± 0.734
5.159SerArg: 5.159 ± 3.983
12.664SerSer: 12.664 ± 4.7
7.974SerThr: 7.974 ± 2.294
5.159SerVal: 5.159 ± 3.151
2.345SerTrp: 2.345 ± 0.563
4.221SerTyr: 4.221 ± 1.485
0.0SerXaa: 0.0 ± 0.0
Thr
2.345ThrAla: 2.345 ± 0.921
2.345ThrCys: 2.345 ± 1.029
4.221ThrAsp: 4.221 ± 1.686
2.814ThrGlu: 2.814 ± 0.729
2.345ThrPhe: 2.345 ± 1.265
5.629ThrGly: 5.629 ± 1.968
1.407ThrHis: 1.407 ± 0.718
6.098ThrIle: 6.098 ± 1.821
2.814ThrLys: 2.814 ± 1.412
2.814ThrLeu: 2.814 ± 0.927
2.345ThrMet: 2.345 ± 1.049
2.814ThrAsn: 2.814 ± 1.387
2.345ThrPro: 2.345 ± 1.022
3.752ThrGln: 3.752 ± 0.708
4.221ThrArg: 4.221 ± 1.694
5.629ThrSer: 5.629 ± 1.284
6.567ThrThr: 6.567 ± 1.555
2.814ThrVal: 2.814 ± 1.64
1.407ThrTrp: 1.407 ± 0.562
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.283ValAla: 3.283 ± 0.962
1.407ValCys: 1.407 ± 0.859
1.407ValAsp: 1.407 ± 0.859
3.283ValGlu: 3.283 ± 1.768
2.814ValPhe: 2.814 ± 1.246
4.221ValGly: 4.221 ± 2.013
0.469ValHis: 0.469 ± 0.666
3.752ValIle: 3.752 ± 0.873
4.221ValLys: 4.221 ± 1.644
4.69ValLeu: 4.69 ± 1.91
1.876ValMet: 1.876 ± 0.752
2.814ValAsn: 2.814 ± 0.918
4.69ValPro: 4.69 ± 1.835
2.814ValGln: 2.814 ± 0.729
2.345ValArg: 2.345 ± 0.555
4.69ValSer: 4.69 ± 1.121
2.345ValThr: 2.345 ± 0.967
2.814ValVal: 2.814 ± 2.654
0.938ValTrp: 0.938 ± 0.573
0.938ValTyr: 0.938 ± 0.815
0.0ValXaa: 0.0 ± 0.0
Trp
0.938TrpAla: 0.938 ± 0.573
0.0TrpCys: 0.0 ± 0.0
1.407TrpAsp: 1.407 ± 0.601
1.407TrpGlu: 1.407 ± 0.562
0.0TrpPhe: 0.0 ± 0.0
1.876TrpGly: 1.876 ± 0.765
0.469TrpHis: 0.469 ± 0.722
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.876TrpLeu: 1.876 ± 0.885
0.469TrpMet: 0.469 ± 0.286
0.938TrpAsn: 0.938 ± 0.459
0.469TrpPro: 0.469 ± 0.286
0.0TrpGln: 0.0 ± 0.0
1.407TrpArg: 1.407 ± 0.562
3.752TrpSer: 3.752 ± 1.713
3.283TrpThr: 3.283 ± 1.306
0.938TrpVal: 0.938 ± 0.573
0.0TrpTrp: 0.0 ± 0.0
0.469TrpTyr: 0.469 ± 0.519
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.407TyrAla: 1.407 ± 0.562
0.0TyrCys: 0.0 ± 0.0
2.345TyrAsp: 2.345 ± 1.009
0.938TyrGlu: 0.938 ± 0.632
0.0TyrPhe: 0.0 ± 0.0
4.221TyrGly: 4.221 ± 1.76
1.876TyrHis: 1.876 ± 0.859
1.876TyrIle: 1.876 ± 0.487
2.345TyrLys: 2.345 ± 1.265
1.407TyrLeu: 1.407 ± 0.562
0.469TyrMet: 0.469 ± 0.286
3.283TyrAsn: 3.283 ± 1.187
1.407TyrPro: 1.407 ± 1.202
0.938TyrGln: 0.938 ± 0.815
1.407TyrArg: 1.407 ± 0.859
2.345TyrSer: 2.345 ± 0.986
0.469TyrThr: 0.469 ± 0.286
0.938TyrVal: 0.938 ± 0.573
0.0TyrTrp: 0.0 ± 0.0
0.469TyrTyr: 0.469 ± 0.666
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2133 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski