Amino acid dipepetide frequency for Bos taurus papillomavirus 2 (Bovine papillomavirus 2)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.65AlaAla: 5.65 ± 0.569
2.421AlaCys: 2.421 ± 1.275
3.228AlaAsp: 3.228 ± 0.586
4.843AlaGlu: 4.843 ± 1.418
2.825AlaPhe: 2.825 ± 1.087
8.878AlaGly: 8.878 ± 2.505
0.0AlaHis: 0.0 ± 0.0
2.018AlaIle: 2.018 ± 0.989
3.228AlaLys: 3.228 ± 1.254
7.264AlaLeu: 7.264 ± 2.108
1.211AlaMet: 1.211 ± 0.641
3.228AlaAsn: 3.228 ± 1.126
3.632AlaPro: 3.632 ± 1.428
3.632AlaGln: 3.632 ± 1.226
5.65AlaArg: 5.65 ± 1.435
5.65AlaSer: 5.65 ± 1.028
4.843AlaThr: 4.843 ± 2.047
5.65AlaVal: 5.65 ± 1.473
0.404AlaTrp: 0.404 ± 0.324
2.018AlaTyr: 2.018 ± 1.028
0.0AlaXaa: 0.0 ± 0.0
Cys
2.018CysAla: 2.018 ± 1.1
1.211CysCys: 1.211 ± 1.261
0.0CysAsp: 0.0 ± 0.0
1.211CysGlu: 1.211 ± 0.633
1.211CysPhe: 1.211 ± 0.719
1.614CysGly: 1.614 ± 1.267
0.404CysHis: 0.404 ± 0.538
0.807CysIle: 0.807 ± 1.001
1.614CysLys: 1.614 ± 1.095
2.018CysLeu: 2.018 ± 1.277
0.404CysMet: 0.404 ± 0.58
0.404CysAsn: 0.404 ± 0.361
1.211CysPro: 1.211 ± 0.683
0.404CysGln: 0.404 ± 0.373
1.614CysArg: 1.614 ± 1.178
4.036CysSer: 4.036 ± 1.37
2.421CysThr: 2.421 ± 1.01
0.807CysVal: 0.807 ± 0.605
0.404CysTrp: 0.404 ± 0.361
1.211CysTyr: 1.211 ± 1.221
0.0CysXaa: 0.0 ± 0.0
Asp
4.439AspAla: 4.439 ± 1.001
1.211AspCys: 1.211 ± 0.803
2.421AspAsp: 2.421 ± 0.796
1.614AspGlu: 1.614 ± 0.978
4.439AspPhe: 4.439 ± 0.69
4.843AspGly: 4.843 ± 1.343
1.614AspHis: 1.614 ± 0.547
0.404AspIle: 0.404 ± 0.324
2.421AspLys: 2.421 ± 0.75
5.65AspLeu: 5.65 ± 1.55
1.211AspMet: 1.211 ± 0.434
1.614AspAsn: 1.614 ± 0.689
2.018AspPro: 2.018 ± 0.905
0.807AspGln: 0.807 ± 0.434
3.632AspArg: 3.632 ± 1.171
4.439AspSer: 4.439 ± 1.666
4.439AspThr: 4.439 ± 1.96
2.018AspVal: 2.018 ± 1.473
0.404AspTrp: 0.404 ± 0.361
0.404AspTyr: 0.404 ± 0.324
0.0AspXaa: 0.0 ± 0.0
Glu
4.036GluAla: 4.036 ± 0.919
1.211GluCys: 1.211 ± 0.789
5.246GluAsp: 5.246 ± 1.689
8.475GluGlu: 8.475 ± 2.334
0.807GluPhe: 0.807 ± 0.747
3.228GluGly: 3.228 ± 0.699
1.211GluHis: 1.211 ± 0.708
2.421GluIle: 2.421 ± 1.347
2.825GluLys: 2.825 ± 0.819
4.036GluLeu: 4.036 ± 0.844
0.807GluMet: 0.807 ± 0.711
4.036GluAsn: 4.036 ± 0.72
4.036GluPro: 4.036 ± 1.59
2.421GluGln: 2.421 ± 1.372
3.228GluArg: 3.228 ± 1.161
2.825GluSer: 2.825 ± 1.379
5.65GluThr: 5.65 ± 1.182
1.614GluVal: 1.614 ± 0.898
0.404GluTrp: 0.404 ± 0.361
1.614GluTyr: 1.614 ± 0.925
0.0GluXaa: 0.0 ± 0.0
Phe
2.421PheAla: 2.421 ± 0.741
0.404PheCys: 0.404 ± 0.58
1.211PheAsp: 1.211 ± 0.699
2.421PheGlu: 2.421 ± 0.982
2.825PhePhe: 2.825 ± 1.065
4.036PheGly: 4.036 ± 0.839
1.211PheHis: 1.211 ± 0.716
1.614PheIle: 1.614 ± 0.606
2.825PheLys: 2.825 ± 1.268
6.053PheLeu: 6.053 ± 2.055
1.211PheMet: 1.211 ± 0.805
2.018PheAsn: 2.018 ± 1.014
0.807PhePro: 0.807 ± 0.434
0.807PheGln: 0.807 ± 0.721
2.825PheArg: 2.825 ± 0.915
3.632PheSer: 3.632 ± 1.412
2.018PheThr: 2.018 ± 0.956
1.211PheVal: 1.211 ± 0.656
1.211PheTrp: 1.211 ± 0.693
0.807PheTyr: 0.807 ± 0.647
0.0PheXaa: 0.0 ± 0.0
Gly
6.457GlyAla: 6.457 ± 0.851
1.211GlyCys: 1.211 ± 0.636
3.632GlyAsp: 3.632 ± 1.167
4.439GlyGlu: 4.439 ± 0.974
2.825GlyPhe: 2.825 ± 1.407
6.457GlyGly: 6.457 ± 1.974
2.018GlyHis: 2.018 ± 0.834
2.421GlyIle: 2.421 ± 1.453
3.632GlyLys: 3.632 ± 2.038
7.667GlyLeu: 7.667 ± 2.095
0.807GlyMet: 0.807 ± 0.434
2.825GlyAsn: 2.825 ± 0.903
4.843GlyPro: 4.843 ± 2.533
2.825GlyGln: 2.825 ± 1.169
4.036GlyArg: 4.036 ± 0.877
9.685GlySer: 9.685 ± 1.337
4.843GlyThr: 4.843 ± 1.178
4.439GlyVal: 4.439 ± 0.681
0.807GlyTrp: 0.807 ± 0.747
0.807GlyTyr: 0.807 ± 0.575
0.0GlyXaa: 0.0 ± 0.0
His
2.018HisAla: 2.018 ± 1.072
0.404HisCys: 0.404 ± 0.373
0.807HisAsp: 0.807 ± 0.721
1.211HisGlu: 1.211 ± 0.718
2.421HisPhe: 2.421 ± 0.73
1.614HisGly: 1.614 ± 1.273
0.0HisHis: 0.0 ± 0.0
1.211HisIle: 1.211 ± 0.669
1.211HisLys: 1.211 ± 1.082
2.421HisLeu: 2.421 ± 0.943
0.404HisMet: 0.404 ± 0.324
0.404HisAsn: 0.404 ± 0.324
2.018HisPro: 2.018 ± 0.798
1.614HisGln: 1.614 ± 1.102
1.614HisArg: 1.614 ± 0.891
0.807HisSer: 0.807 ± 0.429
0.807HisThr: 0.807 ± 0.46
2.421HisVal: 2.421 ± 1.195
0.0HisTrp: 0.0 ± 0.0
0.807HisTyr: 0.807 ± 0.429
0.0HisXaa: 0.0 ± 0.0
Ile
2.825IleAla: 2.825 ± 1.051
1.211IleCys: 1.211 ± 1.173
2.421IleAsp: 2.421 ± 1.045
3.228IleGlu: 3.228 ± 0.985
1.614IlePhe: 1.614 ± 0.826
3.228IleGly: 3.228 ± 1.62
0.404IleHis: 0.404 ± 0.361
1.614IleIle: 1.614 ± 1.155
2.018IleLys: 2.018 ± 1.057
4.439IleLeu: 4.439 ± 1.024
0.0IleMet: 0.0 ± 0.0
1.211IleAsn: 1.211 ± 0.785
2.825IlePro: 2.825 ± 2.04
0.807IleGln: 0.807 ± 0.647
2.018IleArg: 2.018 ± 1.34
1.614IleSer: 1.614 ± 0.662
2.825IleThr: 2.825 ± 0.864
0.404IleVal: 0.404 ± 0.398
0.404IleTrp: 0.404 ± 0.324
0.807IleTyr: 0.807 ± 0.46
0.0IleXaa: 0.0 ± 0.0
Lys
2.825LysAla: 2.825 ± 1.289
0.807LysCys: 0.807 ± 0.434
2.018LysAsp: 2.018 ± 0.854
4.036LysGlu: 4.036 ± 1.529
1.211LysPhe: 1.211 ± 0.636
2.825LysGly: 2.825 ± 1.061
2.421LysHis: 2.421 ± 0.75
2.421LysIle: 2.421 ± 0.933
4.439LysLys: 4.439 ± 1.609
4.843LysLeu: 4.843 ± 1.309
1.211LysMet: 1.211 ± 1.173
3.632LysAsn: 3.632 ± 1.075
0.807LysPro: 0.807 ± 0.57
2.421LysGln: 2.421 ± 0.534
5.65LysArg: 5.65 ± 1.635
5.246LysSer: 5.246 ± 2.433
2.825LysThr: 2.825 ± 0.823
2.421LysVal: 2.421 ± 0.925
0.0LysTrp: 0.0 ± 0.0
0.807LysTyr: 0.807 ± 0.675
0.0LysXaa: 0.0 ± 0.0
Leu
6.86LeuAla: 6.86 ± 1.891
3.228LeuCys: 3.228 ± 1.12
7.264LeuAsp: 7.264 ± 1.264
4.439LeuGlu: 4.439 ± 1.28
4.439LeuPhe: 4.439 ± 2.001
6.86LeuGly: 6.86 ± 1.203
3.228LeuHis: 3.228 ± 0.989
4.036LeuIle: 4.036 ± 1.182
7.264LeuLys: 7.264 ± 1.417
14.528LeuLeu: 14.528 ± 3.619
2.018LeuMet: 2.018 ± 0.832
2.018LeuAsn: 2.018 ± 0.66
5.65LeuPro: 5.65 ± 1.83
5.246LeuGln: 5.246 ± 1.068
3.228LeuArg: 3.228 ± 1.104
7.264LeuSer: 7.264 ± 1.375
4.439LeuThr: 4.439 ± 1.552
4.439LeuVal: 4.439 ± 1.319
2.018LeuTrp: 2.018 ± 0.97
5.246LeuTyr: 5.246 ± 1.396
0.0LeuXaa: 0.0 ± 0.0
Met
2.018MetAla: 2.018 ± 0.712
0.0MetCys: 0.0 ± 0.0
0.404MetAsp: 0.404 ± 0.58
1.211MetGlu: 1.211 ± 0.669
0.404MetPhe: 0.404 ± 0.324
0.404MetGly: 0.404 ± 0.592
0.0MetHis: 0.0 ± 0.0
0.807MetIle: 0.807 ± 1.001
0.404MetLys: 0.404 ± 0.592
1.614MetLeu: 1.614 ± 0.92
0.404MetMet: 0.404 ± 0.324
0.807MetAsn: 0.807 ± 0.434
1.211MetPro: 1.211 ± 0.57
2.018MetGln: 2.018 ± 0.941
1.211MetArg: 1.211 ± 0.67
0.807MetSer: 0.807 ± 0.46
0.0MetThr: 0.0 ± 0.0
1.211MetVal: 1.211 ± 0.808
0.0MetTrp: 0.0 ± 0.0
0.404MetTyr: 0.404 ± 0.398
0.0MetXaa: 0.0 ± 0.0
Asn
4.439AsnAla: 4.439 ± 1.526
1.211AsnCys: 1.211 ± 0.716
0.807AsnAsp: 0.807 ± 0.721
2.825AsnGlu: 2.825 ± 1.422
0.0AsnPhe: 0.0 ± 0.0
1.211AsnGly: 1.211 ± 0.401
1.211AsnHis: 1.211 ± 0.699
2.825AsnIle: 2.825 ± 0.705
0.404AsnLys: 0.404 ± 0.324
3.632AsnLeu: 3.632 ± 0.985
0.404AsnMet: 0.404 ± 0.361
1.211AsnAsn: 1.211 ± 0.73
1.211AsnPro: 1.211 ± 0.599
2.018AsnGln: 2.018 ± 0.862
2.018AsnArg: 2.018 ± 0.824
2.825AsnSer: 2.825 ± 0.988
3.228AsnThr: 3.228 ± 0.764
1.614AsnVal: 1.614 ± 0.627
2.018AsnTrp: 2.018 ± 0.573
0.807AsnTyr: 0.807 ± 0.405
0.0AsnXaa: 0.0 ± 0.0
Pro
7.264ProAla: 7.264 ± 1.371
2.018ProCys: 2.018 ± 1.08
5.246ProAsp: 5.246 ± 2.49
2.825ProGlu: 2.825 ± 1.329
1.614ProPhe: 1.614 ± 1.356
2.825ProGly: 2.825 ± 1.121
0.807ProHis: 0.807 ± 0.747
1.614ProIle: 1.614 ± 1.144
2.825ProLys: 2.825 ± 0.617
6.86ProLeu: 6.86 ± 1.975
0.404ProMet: 0.404 ± 0.574
1.614ProAsn: 1.614 ± 0.638
6.053ProPro: 6.053 ± 2.513
0.807ProGln: 0.807 ± 0.797
3.632ProArg: 3.632 ± 1.864
5.246ProSer: 5.246 ± 2.52
3.228ProThr: 3.228 ± 1.744
3.228ProVal: 3.228 ± 1.271
0.404ProTrp: 0.404 ± 0.373
1.614ProTyr: 1.614 ± 0.957
0.0ProXaa: 0.0 ± 0.0
Gln
4.036GlnAla: 4.036 ± 1.661
0.404GlnCys: 0.404 ± 0.361
1.614GlnAsp: 1.614 ± 1.062
2.018GlnGlu: 2.018 ± 1.593
1.211GlnPhe: 1.211 ± 0.971
5.65GlnGly: 5.65 ± 0.935
0.0GlnHis: 0.0 ± 0.0
2.018GlnIle: 2.018 ± 0.5
1.614GlnLys: 1.614 ± 0.763
4.843GlnLeu: 4.843 ± 1.545
0.807GlnMet: 0.807 ± 0.429
1.211GlnAsn: 1.211 ± 0.636
3.228GlnPro: 3.228 ± 0.752
2.421GlnGln: 2.421 ± 1.248
1.614GlnArg: 1.614 ± 0.778
1.614GlnSer: 1.614 ± 0.862
3.228GlnThr: 3.228 ± 0.996
3.228GlnVal: 3.228 ± 1.155
0.807GlnTrp: 0.807 ± 0.721
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.246ArgAla: 5.246 ± 0.609
2.825ArgCys: 2.825 ± 1.848
1.614ArgAsp: 1.614 ± 1.266
1.211ArgGlu: 1.211 ± 0.808
2.421ArgPhe: 2.421 ± 1.12
4.843ArgGly: 4.843 ± 1.518
3.228ArgHis: 3.228 ± 1.293
0.404ArgIle: 0.404 ± 0.373
6.053ArgLys: 6.053 ± 1.839
4.036ArgLeu: 4.036 ± 1.548
0.0ArgMet: 0.0 ± 0.487
2.825ArgAsn: 2.825 ± 1.091
4.439ArgPro: 4.439 ± 1.514
2.421ArgGln: 2.421 ± 1.207
2.421ArgArg: 2.421 ± 0.749
1.614ArgSer: 1.614 ± 0.563
3.228ArgThr: 3.228 ± 1.001
4.843ArgVal: 4.843 ± 1.456
0.404ArgTrp: 0.404 ± 0.51
4.439ArgTyr: 4.439 ± 0.825
0.0ArgXaa: 0.0 ± 0.0
Ser
3.632SerAla: 3.632 ± 1.146
0.807SerCys: 0.807 ± 0.614
3.228SerAsp: 3.228 ± 1.18
4.439SerGlu: 4.439 ± 1.533
2.421SerPhe: 2.421 ± 1.88
5.65SerGly: 5.65 ± 1.068
2.421SerHis: 2.421 ± 1.29
3.632SerIle: 3.632 ± 1.423
4.439SerLys: 4.439 ± 1.226
9.685SerLeu: 9.685 ± 2.473
1.614SerMet: 1.614 ± 1.029
3.228SerAsn: 3.228 ± 0.93
5.65SerPro: 5.65 ± 2.208
2.018SerGln: 2.018 ± 0.859
3.228SerArg: 3.228 ± 1.047
6.053SerSer: 6.053 ± 1.394
6.053SerThr: 6.053 ± 2.852
5.246SerVal: 5.246 ± 1.05
1.211SerTrp: 1.211 ± 0.67
0.404SerTyr: 0.404 ± 0.361
0.0SerXaa: 0.0 ± 0.0
Thr
4.036ThrAla: 4.036 ± 1.052
2.018ThrCys: 2.018 ± 0.827
2.421ThrAsp: 2.421 ± 0.933
5.246ThrGlu: 5.246 ± 1.266
3.228ThrPhe: 3.228 ± 1.052
7.264ThrGly: 7.264 ± 1.881
0.807ThrHis: 0.807 ± 0.584
2.421ThrIle: 2.421 ± 1.234
1.211ThrLys: 1.211 ± 0.778
4.036ThrLeu: 4.036 ± 0.941
1.211ThrMet: 1.211 ± 0.699
2.018ThrAsn: 2.018 ± 0.941
4.439ThrPro: 4.439 ± 1.254
2.421ThrGln: 2.421 ± 0.664
4.036ThrArg: 4.036 ± 1.21
3.632ThrSer: 3.632 ± 1.782
5.246ThrThr: 5.246 ± 0.761
7.264ThrVal: 7.264 ± 2.278
1.211ThrTrp: 1.211 ± 0.674
2.018ThrTyr: 2.018 ± 0.836
0.0ThrXaa: 0.0 ± 0.0
Val
3.228ValAla: 3.228 ± 1.278
1.211ValCys: 1.211 ± 1.144
2.825ValAsp: 2.825 ± 0.888
2.825ValGlu: 2.825 ± 0.575
2.825ValPhe: 2.825 ± 1.181
3.632ValGly: 3.632 ± 2.136
1.211ValHis: 1.211 ± 0.73
2.018ValIle: 2.018 ± 1.07
2.421ValLys: 2.421 ± 0.782
4.843ValLeu: 4.843 ± 0.805
0.0ValMet: 0.0 ± 0.0
0.807ValAsn: 0.807 ± 0.403
4.439ValPro: 4.439 ± 1.332
4.439ValGln: 4.439 ± 1.853
4.439ValArg: 4.439 ± 0.92
4.036ValSer: 4.036 ± 1.401
4.439ValThr: 4.439 ± 1.012
1.614ValVal: 1.614 ± 0.862
1.211ValTrp: 1.211 ± 0.673
3.632ValTyr: 3.632 ± 0.872
0.0ValXaa: 0.0 ± 0.0
Trp
0.807TrpAla: 0.807 ± 0.403
0.404TrpCys: 0.404 ± 0.58
1.211TrpAsp: 1.211 ± 0.605
0.404TrpGlu: 0.404 ± 0.324
1.614TrpPhe: 1.614 ± 0.547
0.807TrpGly: 0.807 ± 0.616
0.404TrpHis: 0.404 ± 0.51
0.404TrpIle: 0.404 ± 0.361
1.211TrpLys: 1.211 ± 0.913
1.211TrpLeu: 1.211 ± 0.693
0.0TrpMet: 0.0 ± 0.0
0.404TrpAsn: 0.404 ± 0.324
0.0TrpPro: 0.0 ± 0.0
1.211TrpGln: 1.211 ± 0.488
0.404TrpArg: 0.404 ± 0.361
1.211TrpSer: 1.211 ± 0.488
1.614TrpThr: 1.614 ± 0.8
1.211TrpVal: 1.211 ± 0.719
0.0TrpTrp: 0.0 ± 0.0
0.404TrpTyr: 0.404 ± 0.373
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.018TyrAla: 2.018 ± 0.765
0.807TyrCys: 0.807 ± 0.692
2.421TyrAsp: 2.421 ± 0.723
1.211TyrGlu: 1.211 ± 0.363
1.211TyrPhe: 1.211 ± 0.628
0.807TyrGly: 0.807 ± 0.623
1.614TyrHis: 1.614 ± 0.689
0.807TyrIle: 0.807 ± 0.403
0.807TyrLys: 0.807 ± 0.624
4.036TyrLeu: 4.036 ± 1.914
0.807TyrMet: 0.807 ± 0.747
0.404TyrAsn: 0.404 ± 0.58
1.614TyrPro: 1.614 ± 0.53
0.807TyrGln: 0.807 ± 0.403
2.421TyrArg: 2.421 ± 0.822
2.825TyrSer: 2.825 ± 1.481
0.807TyrThr: 0.807 ± 0.46
1.211TyrVal: 1.211 ± 0.73
1.614TyrTrp: 1.614 ± 0.833
1.614TyrTyr: 1.614 ± 0.717
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (2479 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski