Amino acid dipepetide frequency for Triticum turgidum subsp. durum (Durum wheat) (Triticum durum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.488AlaAla: 10.488 ± 0.02	1.439AlaCys: 1.439 ± 0.004	4.191AlaAsp: 4.191 ± 0.008	4.953AlaGlu: 4.953 ± 0.011	2.806AlaPhe: 2.806 ± 0.007	5.815AlaGly: 5.815 ± 0.01	1.677AlaHis: 1.677 ± 0.004	3.659AlaIle: 3.659 ± 0.007	3.949AlaLys: 3.949 ± 0.008	7.604AlaLeu: 7.604 ± 0.011	2.151AlaMet: 2.151 ± 0.006	2.715AlaAsn: 2.715 ± 0.006	4.314AlaPro: 4.314 ± 0.01	2.527AlaGln: 2.527 ± 0.006	4.583AlaArg: 4.583 ± 0.009	6.966AlaSer: 6.966 ± 0.011	4.322AlaThr: 4.322 ± 0.008	6.084AlaVal: 6.084 ± 0.011	0.89AlaTrp: 0.89 ± 0.004	1.949AlaTyr: 1.949 ± 0.005	0.004AlaXaa: 0.004 ± 0.0
Cys	1.227CysAla: 1.227 ± 0.004	0.537CysCys: 0.537 ± 0.003	0.886CysAsp: 0.886 ± 0.004	0.844CysGlu: 0.844 ± 0.003	0.818CysPhe: 0.818 ± 0.003	1.405CysGly: 1.405 ± 0.006	0.492CysHis: 0.492 ± 0.002	0.976CysIle: 0.976 ± 0.004	0.989CysLys: 0.989 ± 0.004	1.84CysLeu: 1.84 ± 0.006	0.468CysMet: 0.468 ± 0.002	0.71CysAsn: 0.71 ± 0.003	0.949CysPro: 0.949 ± 0.004	0.612CysGln: 0.612 ± 0.003	1.137CysArg: 1.137 ± 0.004	1.799CysSer: 1.799 ± 0.006	0.932CysThr: 0.932 ± 0.004	1.1CysVal: 1.1 ± 0.004	0.247CysTrp: 0.247 ± 0.002	0.529CysTyr: 0.529 ± 0.002	0.001CysXaa: 0.001 ± 0.0
Asp	4.629AspAla: 4.629 ± 0.008	0.93AspCys: 0.93 ± 0.004	4.144AspAsp: 4.144 ± 0.01	4.058AspGlu: 4.058 ± 0.009	2.121AspPhe: 2.121 ± 0.005	4.487AspGly: 4.487 ± 0.008	1.289AspHis: 1.289 ± 0.004	2.982AspIle: 2.982 ± 0.007	2.758AspLys: 2.758 ± 0.007	5.176AspLeu: 5.176 ± 0.009	1.501AspMet: 1.501 ± 0.004	2.016AspAsn: 2.016 ± 0.006	2.751AspPro: 2.751 ± 0.007	1.749AspGln: 1.749 ± 0.005	2.671AspArg: 2.671 ± 0.007	3.929AspSer: 3.929 ± 0.008	2.451AspThr: 2.451 ± 0.006	3.922AspVal: 3.922 ± 0.008	0.707AspTrp: 0.707 ± 0.003	1.491AspTyr: 1.491 ± 0.004	0.001AspXaa: 0.001 ± 0.0
Glu	5.239GluAla: 5.239 ± 0.011	0.9GluCys: 0.9 ± 0.003	3.954GluAsp: 3.954 ± 0.009	5.737GluGlu: 5.737 ± 0.015	2.113GluPhe: 2.113 ± 0.005	3.775GluGly: 3.775 ± 0.007	1.463GluHis: 1.463 ± 0.005	3.187GluIle: 3.187 ± 0.007	4.069GluLys: 4.069 ± 0.011	6.087GluLeu: 6.087 ± 0.011	1.673GluMet: 1.673 ± 0.005	2.487GluAsn: 2.487 ± 0.007	2.353GluPro: 2.353 ± 0.006	2.353GluGln: 2.353 ± 0.006	3.48GluArg: 3.48 ± 0.008	4.088GluSer: 4.088 ± 0.008	2.772GluThr: 2.772 ± 0.007	4.189GluVal: 4.189 ± 0.007	0.727GluTrp: 0.727 ± 0.003	1.624GluTyr: 1.624 ± 0.005	0.002GluXaa: 0.002 ± 0.0
Phe	2.712PheAla: 2.712 ± 0.006	0.784PheCys: 0.784 ± 0.003	2.208PheAsp: 2.208 ± 0.005	1.992PheGlu: 1.992 ± 0.005	1.659PhePhe: 1.659 ± 0.005	2.923PheGly: 2.923 ± 0.008	0.978PheHis: 0.978 ± 0.003	1.728PheIle: 1.728 ± 0.005	1.641PheLys: 1.641 ± 0.005	3.836PheLeu: 3.836 ± 0.007	0.912PheMet: 0.912 ± 0.004	1.385PheAsn: 1.385 ± 0.004	1.877PhePro: 1.877 ± 0.006	1.352PheGln: 1.352 ± 0.004	2.014PheArg: 2.014 ± 0.005	3.408PheSer: 3.408 ± 0.007	1.795PheThr: 1.795 ± 0.005	2.606PheVal: 2.606 ± 0.006	0.517PheTrp: 0.517 ± 0.003	1.11PheTyr: 1.11 ± 0.004	0.001PheXaa: 0.001 ± 0.0
Gly	5.531GlyAla: 5.531 ± 0.011	1.351GlyCys: 1.351 ± 0.005	3.907GlyAsp: 3.907 ± 0.008	3.851GlyGlu: 3.851 ± 0.007	2.837GlyPhe: 2.837 ± 0.007	6.454GlyGly: 6.454 ± 0.016	1.752GlyHis: 1.752 ± 0.005	3.294GlyIle: 3.294 ± 0.007	3.845GlyLys: 3.845 ± 0.007	5.984GlyLeu: 5.984 ± 0.01	1.745GlyMet: 1.745 ± 0.004	2.862GlyAsn: 2.862 ± 0.007	2.74GlyPro: 2.74 ± 0.006	2.35GlyGln: 2.35 ± 0.006	4.268GlyArg: 4.268 ± 0.009	6.19GlySer: 6.19 ± 0.011	3.595GlyThr: 3.595 ± 0.008	4.469GlyVal: 4.469 ± 0.008	0.926GlyTrp: 0.926 ± 0.004	2.06GlyTyr: 2.06 ± 0.006	0.003GlyXaa: 0.003 ± 0.0
His	1.857HisAla: 1.857 ± 0.005	0.504HisCys: 0.504 ± 0.002	1.353HisAsp: 1.353 ± 0.004	1.314HisGlu: 1.314 ± 0.004	0.954HisPhe: 0.954 ± 0.004	1.998HisGly: 1.998 ± 0.005	0.949HisHis: 0.949 ± 0.005	1.18HisIle: 1.18 ± 0.004	1.069HisLys: 1.069 ± 0.004	2.553HisLeu: 2.553 ± 0.006	0.613HisMet: 0.613 ± 0.003	0.872HisAsn: 0.872 ± 0.003	1.46HisPro: 1.46 ± 0.005	1.018HisGln: 1.018 ± 0.004	1.534HisArg: 1.534 ± 0.004	1.793HisSer: 1.793 ± 0.005	1.056HisThr: 1.056 ± 0.004	1.672HisVal: 1.672 ± 0.004	0.3HisTrp: 0.3 ± 0.002	0.661HisTyr: 0.661 ± 0.003	0.001HisXaa: 0.001 ± 0.0
Ile	3.569IleAla: 3.569 ± 0.007	1.007IleCys: 1.007 ± 0.004	2.693IleAsp: 2.693 ± 0.006	2.679IleGlu: 2.679 ± 0.007	1.912IlePhe: 1.912 ± 0.005	3.128IleGly: 3.128 ± 0.006	1.182IleHis: 1.182 ± 0.004	2.457IleIle: 2.457 ± 0.006	2.459IleLys: 2.459 ± 0.005	4.657IleLeu: 4.657 ± 0.01	1.092IleMet: 1.092 ± 0.004	1.796IleAsn: 1.796 ± 0.005	2.55IlePro: 2.55 ± 0.008	1.768IleGln: 1.768 ± 0.005	2.453IleArg: 2.453 ± 0.006	4.121IleSer: 4.121 ± 0.008	2.417IleThr: 2.417 ± 0.005	3.21IleVal: 3.21 ± 0.006	0.639IleTrp: 0.639 ± 0.003	1.324IleTyr: 1.324 ± 0.004	0.001IleXaa: 0.001 ± 0.0
Lys	4.022LysAla: 4.022 ± 0.008	0.86LysCys: 0.86 ± 0.004	3.092LysAsp: 3.092 ± 0.008	4.07LysGlu: 4.07 ± 0.012	1.772LysPhe: 1.772 ± 0.005	3.283LysGly: 3.283 ± 0.008	1.275LysHis: 1.275 ± 0.005	2.775LysIle: 2.775 ± 0.007	3.846LysLys: 3.846 ± 0.011	5.315LysLeu: 5.315 ± 0.01	1.362LysMet: 1.362 ± 0.004	2.094LysAsn: 2.094 ± 0.006	2.413LysPro: 2.413 ± 0.006	2.107LysGln: 2.107 ± 0.006	3.256LysArg: 3.256 ± 0.008	3.784LysSer: 3.784 ± 0.007	2.488LysThr: 2.488 ± 0.005	3.537LysVal: 3.537 ± 0.007	0.625LysTrp: 0.625 ± 0.003	1.467LysTyr: 1.467 ± 0.005	0.002LysXaa: 0.002 ± 0.0
Leu	7.727LeuAla: 7.727 ± 0.011	1.876LeuCys: 1.876 ± 0.005	5.313LeuAsp: 5.313 ± 0.009	6.086LeuGlu: 6.086 ± 0.013	3.474LeuPhe: 3.474 ± 0.007	5.945LeuGly: 5.945 ± 0.01	2.726LeuHis: 2.726 ± 0.007	3.925LeuIle: 3.925 ± 0.008	5.328LeuLys: 5.328 ± 0.011	10.356LeuLeu: 10.356 ± 0.016	2.127LeuMet: 2.127 ± 0.005	3.29LeuAsn: 3.29 ± 0.006	5.563LeuPro: 5.563 ± 0.01	4.392LeuGln: 4.392 ± 0.009	6.023LeuArg: 6.023 ± 0.011	8.078LeuSer: 8.078 ± 0.013	4.359LeuThr: 4.359 ± 0.008	6.594LeuVal: 6.594 ± 0.011	1.116LeuTrp: 1.116 ± 0.004	2.404LeuTyr: 2.404 ± 0.006	0.003LeuXaa: 0.003 ± 0.0
Met	2.423MetAla: 2.423 ± 0.006	0.368MetCys: 0.368 ± 0.002	1.572MetAsp: 1.572 ± 0.005	1.899MetGlu: 1.899 ± 0.004	0.826MetPhe: 0.826 ± 0.003	1.599MetGly: 1.599 ± 0.005	0.626MetHis: 0.626 ± 0.003	1.046MetIle: 1.046 ± 0.003	1.412MetLys: 1.412 ± 0.004	2.418MetLeu: 2.418 ± 0.005	0.716MetMet: 0.716 ± 0.003	0.921MetAsn: 0.921 ± 0.003	1.291MetPro: 1.291 ± 0.004	1.023MetGln: 1.023 ± 0.004	1.303MetArg: 1.303 ± 0.004	1.862MetSer: 1.862 ± 0.005	1.111MetThr: 1.111 ± 0.004	1.711MetVal: 1.711 ± 0.005	0.279MetTrp: 0.279 ± 0.002	0.632MetTyr: 0.632 ± 0.003	0.001MetXaa: 0.001 ± 0.0
Asn	2.678AsnAla: 2.678 ± 0.006	0.722AsnCys: 0.722 ± 0.003	1.905AsnAsp: 1.905 ± 0.005	2.039AsnGlu: 2.039 ± 0.006	1.524AsnPhe: 1.524 ± 0.005	2.941AsnGly: 2.941 ± 0.006	0.942AsnHis: 0.942 ± 0.003	2.161AsnIle: 2.161 ± 0.005	1.987AsnLys: 1.987 ± 0.005	3.911AsnLeu: 3.911 ± 0.01	1.078AsnMet: 1.078 ± 0.004	1.799AsnAsn: 1.799 ± 0.006	1.957AsnPro: 1.957 ± 0.005	1.448AsnGln: 1.448 ± 0.005	1.803AsnArg: 1.803 ± 0.005	3.086AsnSer: 3.086 ± 0.006	1.817AsnThr: 1.817 ± 0.005	2.434AsnVal: 2.434 ± 0.005	0.467AsnTrp: 0.467 ± 0.002	1.054AsnTyr: 1.054 ± 0.004	0.001AsnXaa: 0.001 ± 0.0
Pro	4.703ProAla: 4.703 ± 0.011	0.843ProCys: 0.843 ± 0.003	2.754ProAsp: 2.754 ± 0.006	3.347ProGlu: 3.347 ± 0.007	1.854ProPhe: 1.854 ± 0.005	3.32ProGly: 3.32 ± 0.007	1.187ProHis: 1.187 ± 0.004	1.933ProIle: 1.933 ± 0.005	2.423ProLys: 2.423 ± 0.007	4.403ProLeu: 4.403 ± 0.009	1.101ProMet: 1.101 ± 0.004	1.925ProAsn: 1.925 ± 0.005	4.435ProPro: 4.435 ± 0.014	1.918ProGln: 1.918 ± 0.007	2.978ProArg: 2.978 ± 0.007	5.203ProSer: 5.203 ± 0.011	2.703ProThr: 2.703 ± 0.006	3.46ProVal: 3.46 ± 0.008	0.628ProTrp: 0.628 ± 0.003	1.31ProTyr: 1.31 ± 0.005	0.004ProXaa: 0.004 ± 0.0
Gln	2.687GlnAla: 2.687 ± 0.006	0.611GlnCys: 0.611 ± 0.003	1.803GlnAsp: 1.803 ± 0.005	2.445GlnGlu: 2.445 ± 0.007	1.305GlnPhe: 1.305 ± 0.004	2.323GlnGly: 2.323 ± 0.006	1.079GlnHis: 1.079 ± 0.004	1.798GlnIle: 1.798 ± 0.005	2.07GlnLys: 2.07 ± 0.006	3.771GlnLeu: 3.771 ± 0.008	0.996GlnMet: 0.996 ± 0.004	1.502GlnAsn: 1.502 ± 0.005	1.951GlnPro: 1.951 ± 0.007	2.496GlnGln: 2.496 ± 0.016	2.251GlnArg: 2.251 ± 0.006	2.717GlnSer: 2.717 ± 0.006	1.613GlnThr: 1.613 ± 0.005	2.388GlnVal: 2.388 ± 0.006	0.452GlnTrp: 0.452 ± 0.003	0.993GlnTyr: 0.993 ± 0.003	0.001GlnXaa: 0.001 ± 0.0
Arg	4.336ArgAla: 4.336 ± 0.008	1.133ArgCys: 1.133 ± 0.004	2.972ArgAsp: 2.972 ± 0.006	3.374ArgGlu: 3.374 ± 0.007	2.177ArgPhe: 2.177 ± 0.005	3.736ArgGly: 3.736 ± 0.008	1.489ArgHis: 1.489 ± 0.004	2.644ArgIle: 2.644 ± 0.005	3.436ArgLys: 3.436 ± 0.007	5.638ArgLeu: 5.638 ± 0.01	1.456ArgMet: 1.456 ± 0.004	2.192ArgAsn: 2.192 ± 0.005	2.949ArgPro: 2.949 ± 0.006	2.02ArgGln: 2.02 ± 0.005	4.94ArgArg: 4.94 ± 0.011	4.722ArgSer: 4.722 ± 0.009	2.636ArgThr: 2.636 ± 0.005	3.571ArgVal: 3.571 ± 0.007	0.846ArgTrp: 0.846 ± 0.003	1.594ArgTyr: 1.594 ± 0.005	0.003ArgXaa: 0.003 ± 0.0
Ser	6.406SerAla: 6.406 ± 0.009	1.665SerCys: 1.665 ± 0.006	4.33SerAsp: 4.33 ± 0.007	4.392SerGlu: 4.392 ± 0.01	3.366SerPhe: 3.366 ± 0.007	6.089SerGly: 6.089 ± 0.01	1.85SerHis: 1.85 ± 0.004	3.805SerIle: 3.805 ± 0.007	4.17SerLys: 4.17 ± 0.008	7.995SerLeu: 7.995 ± 0.012	2.084SerMet: 2.084 ± 0.005	3.241SerAsn: 3.241 ± 0.007	4.672SerPro: 4.672 ± 0.012	2.772SerGln: 2.772 ± 0.007	4.641SerArg: 4.641 ± 0.009	9.893SerSer: 9.893 ± 0.016	4.57SerThr: 4.57 ± 0.008	5.185SerVal: 5.185 ± 0.009	1.118SerTrp: 1.118 ± 0.004	2.193SerTyr: 2.193 ± 0.005	0.004SerXaa: 0.004 ± 0.0
Thr	4.06ThrAla: 4.06 ± 0.008	0.925ThrCys: 0.925 ± 0.004	2.435ThrAsp: 2.435 ± 0.006	2.828ThrGlu: 2.828 ± 0.007	1.813ThrPhe: 1.813 ± 0.005	3.638ThrGly: 3.638 ± 0.008	1.012ThrHis: 1.012 ± 0.003	2.477ThrIle: 2.477 ± 0.006	2.438ThrLys: 2.438 ± 0.006	4.478ThrLeu: 4.478 ± 0.008	1.258ThrMet: 1.258 ± 0.004	1.864ThrAsn: 1.864 ± 0.005	2.723ThrPro: 2.723 ± 0.006	1.478ThrGln: 1.478 ± 0.005	2.514ThrArg: 2.514 ± 0.005	4.466ThrSer: 4.466 ± 0.008	2.901ThrThr: 2.901 ± 0.007	3.582ThrVal: 3.582 ± 0.007	0.604ThrTrp: 0.604 ± 0.003	1.335ThrTyr: 1.335 ± 0.005	0.002ThrXaa: 0.002 ± 0.0
Val	5.975ValAla: 5.975 ± 0.01	1.207ValCys: 1.207 ± 0.004	4.03ValAsp: 4.03 ± 0.008	4.191ValGlu: 4.191 ± 0.008	2.476ValPhe: 2.476 ± 0.006	4.354ValGly: 4.354 ± 0.009	1.702ValHis: 1.702 ± 0.005	3.114ValIle: 3.114 ± 0.006	3.464ValLys: 3.464 ± 0.007	6.756ValLeu: 6.756 ± 0.01	1.587ValMet: 1.587 ± 0.004	2.348ValAsn: 2.348 ± 0.006	3.688ValPro: 3.688 ± 0.007	2.462ValGln: 2.462 ± 0.006	3.627ValArg: 3.627 ± 0.007	5.249ValSer: 5.249 ± 0.009	3.337ValThr: 3.337 ± 0.007	5.219ValVal: 5.219 ± 0.01	0.798ValTrp: 0.798 ± 0.003	1.879ValTyr: 1.879 ± 0.005	0.002ValXaa: 0.002 ± 0.0
Trp	0.886TrpAla: 0.886 ± 0.003	0.247TrpCys: 0.247 ± 0.002	0.698TrpAsp: 0.698 ± 0.003	0.731TrpGlu: 0.731 ± 0.003	0.493TrpPhe: 0.493 ± 0.003	0.721TrpGly: 0.721 ± 0.003	0.31TrpHis: 0.31 ± 0.002	0.625TrpIle: 0.625 ± 0.003	0.776TrpLys: 0.776 ± 0.003	1.201TrpLeu: 1.201 ± 0.004	0.36TrpMet: 0.36 ± 0.002	0.567TrpAsn: 0.567 ± 0.003	0.548TrpPro: 0.548 ± 0.003	0.452TrpGln: 0.452 ± 0.002	0.915TrpArg: 0.915 ± 0.003	0.984TrpSer: 0.984 ± 0.004	0.637TrpThr: 0.637 ± 0.003	0.781TrpVal: 0.781 ± 0.003	0.234TrpTrp: 0.234 ± 0.002	0.344TrpTyr: 0.344 ± 0.002	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.925TyrAla: 1.925 ± 0.005	0.586TyrCys: 0.586 ± 0.003	1.521TyrAsp: 1.521 ± 0.004	1.439TyrGlu: 1.439 ± 0.004	1.137TyrPhe: 1.137 ± 0.003	2.079TyrGly: 2.079 ± 0.006	0.735TyrHis: 0.735 ± 0.003	1.345TyrIle: 1.345 ± 0.004	1.315TyrLys: 1.315 ± 0.005	2.723TyrLeu: 2.723 ± 0.007	0.758TyrMet: 0.758 ± 0.003	1.167TyrAsn: 1.167 ± 0.004	1.243TyrPro: 1.243 ± 0.004	0.956TyrGln: 0.956 ± 0.004	1.472TyrArg: 1.472 ± 0.004	2.101TyrSer: 2.101 ± 0.005	1.314TyrThr: 1.314 ± 0.004	1.747TyrVal: 1.747 ± 0.006	0.389TyrTrp: 0.389 ± 0.002	0.929TyrTyr: 0.929 ± 0.003	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.004XaaAla: 0.004 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.001XaaHis: 0.001 ± 0.0	0.002XaaIle: 0.002 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.004XaaLeu: 0.004 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.004XaaPro: 0.004 ± 0.0	0.002XaaGln: 0.002 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.003XaaSer: 0.003 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.003XaaVal: 0.003 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.439XaaXaa: 0.439 ± 0.013

Statistics based on 188121 proteins (87439270 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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