Amino acid dipepetide frequency for Stylophora pistillata (Smooth cauliflower coral)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.593AlaAla: 4.593 ± 0.024	1.15AlaCys: 1.15 ± 0.01	3.28AlaAsp: 3.28 ± 0.017	4.112AlaGlu: 4.112 ± 0.023	2.489AlaPhe: 2.489 ± 0.015	3.461AlaGly: 3.461 ± 0.025	1.252AlaHis: 1.252 ± 0.011	3.409AlaIle: 3.409 ± 0.019	4.255AlaLys: 4.255 ± 0.023	5.873AlaLeu: 5.873 ± 0.029	1.428AlaMet: 1.428 ± 0.009	2.636AlaAsn: 2.636 ± 0.017	2.495AlaPro: 2.495 ± 0.022	2.262AlaGln: 2.262 ± 0.015	3.186AlaArg: 3.186 ± 0.023	5.019AlaSer: 5.019 ± 0.022	3.66AlaThr: 3.66 ± 0.02	4.534AlaVal: 4.534 ± 0.022	0.669AlaTrp: 0.669 ± 0.009	1.586AlaTyr: 1.586 ± 0.014	0.001AlaXaa: 0.001 ± 0.0
Cys	1.147CysAla: 1.147 ± 0.013	0.559CysCys: 0.559 ± 0.01	1.223CysAsp: 1.223 ± 0.015	1.344CysGlu: 1.344 ± 0.016	0.866CysPhe: 0.866 ± 0.009	1.434CysGly: 1.434 ± 0.016	0.606CysHis: 0.606 ± 0.01	1.01CysIle: 1.01 ± 0.01	1.459CysLys: 1.459 ± 0.014	1.953CysLeu: 1.953 ± 0.014	0.39CysMet: 0.39 ± 0.006	0.996CysAsn: 0.996 ± 0.013	1.139CysPro: 1.139 ± 0.032	0.964CysGln: 0.964 ± 0.014	1.17CysArg: 1.17 ± 0.013	1.87CysSer: 1.87 ± 0.02	1.142CysThr: 1.142 ± 0.018	1.356CysVal: 1.356 ± 0.014	0.267CysTrp: 0.267 ± 0.005	0.679CysTyr: 0.679 ± 0.009	0.001CysXaa: 0.001 ± 0.0
Asp	3.115AspAla: 3.115 ± 0.018	1.176AspCys: 1.176 ± 0.014	4.005AspAsp: 4.005 ± 0.033	4.567AspGlu: 4.567 ± 0.028	2.41AspPhe: 2.41 ± 0.015	3.749AspGly: 3.749 ± 0.028	1.297AspHis: 1.297 ± 0.011	3.249AspIle: 3.249 ± 0.02	3.615AspLys: 3.615 ± 0.021	5.123AspLeu: 5.123 ± 0.023	1.152AspMet: 1.152 ± 0.01	2.502AspAsn: 2.502 ± 0.017	2.426AspPro: 2.426 ± 0.015	1.972AspGln: 1.972 ± 0.014	2.684AspArg: 2.684 ± 0.017	4.326AspSer: 4.326 ± 0.026	2.711AspThr: 2.711 ± 0.017	3.87AspVal: 3.87 ± 0.018	0.695AspTrp: 0.695 ± 0.008	1.7AspTyr: 1.7 ± 0.015	0.002AspXaa: 0.002 ± 0.0
Glu	4.376GluAla: 4.376 ± 0.024	1.348GluCys: 1.348 ± 0.019	4.394GluAsp: 4.394 ± 0.023	7.041GluGlu: 7.041 ± 0.057	2.443GluPhe: 2.443 ± 0.013	3.957GluGly: 3.957 ± 0.025	1.486GluHis: 1.486 ± 0.013	3.986GluIle: 3.986 ± 0.021	5.775GluLys: 5.775 ± 0.039	6.131GluLeu: 6.131 ± 0.043	1.73GluMet: 1.73 ± 0.015	3.753GluAsn: 3.753 ± 0.019	2.238GluPro: 2.238 ± 0.017	2.735GluGln: 2.735 ± 0.019	4.188GluArg: 4.188 ± 0.064	4.842GluSer: 4.842 ± 0.026	3.837GluThr: 3.837 ± 0.021	4.395GluVal: 4.395 ± 0.021	0.773GluTrp: 0.773 ± 0.009	1.878GluTyr: 1.878 ± 0.014	0.002GluXaa: 0.002 ± 0.0
Phe	2.232PheAla: 2.232 ± 0.015	0.935PheCys: 0.935 ± 0.011	2.31PheAsp: 2.31 ± 0.012	2.38PheGlu: 2.38 ± 0.016	1.628PhePhe: 1.628 ± 0.014	2.53PheGly: 2.53 ± 0.017	1.094PheHis: 1.094 ± 0.009	2.075PheIle: 2.075 ± 0.014	2.518PheLys: 2.518 ± 0.014	3.75PheLeu: 3.75 ± 0.02	0.821PheMet: 0.821 ± 0.008	1.806PheAsn: 1.806 ± 0.012	1.768PhePro: 1.768 ± 0.013	1.696PheGln: 1.696 ± 0.012	1.949PheArg: 1.949 ± 0.012	3.335PheSer: 3.335 ± 0.018	2.44PheThr: 2.44 ± 0.017	2.74PheVal: 2.74 ± 0.015	0.501PheTrp: 0.501 ± 0.006	1.348PheTyr: 1.348 ± 0.012	0.001PheXaa: 0.001 ± 0.0
Gly	3.407GlyAla: 3.407 ± 0.026	1.23GlyCys: 1.23 ± 0.014	3.53GlyAsp: 3.53 ± 0.027	4.032GlyGlu: 4.032 ± 0.027	2.545GlyPhe: 2.545 ± 0.02	4.317GlyGly: 4.317 ± 0.054	1.491GlyHis: 1.491 ± 0.014	3.215GlyIle: 3.215 ± 0.019	4.485GlyLys: 4.485 ± 0.023	4.711GlyLeu: 4.711 ± 0.022	1.282GlyMet: 1.282 ± 0.012	3.182GlyAsn: 3.182 ± 0.023	2.448GlyPro: 2.448 ± 0.039	2.22GlyGln: 2.22 ± 0.018	3.315GlyArg: 3.315 ± 0.03	4.971GlySer: 4.971 ± 0.032	3.413GlyThr: 3.413 ± 0.025	3.88GlyVal: 3.88 ± 0.023	0.787GlyTrp: 0.787 ± 0.011	1.973GlyTyr: 1.973 ± 0.019	0.002GlyXaa: 0.002 ± 0.0
His	1.257HisAla: 1.257 ± 0.012	0.623HisCys: 0.623 ± 0.008	1.162HisAsp: 1.162 ± 0.01	1.413HisGlu: 1.413 ± 0.013	1.114HisPhe: 1.114 ± 0.008	1.51HisGly: 1.51 ± 0.014	0.736HisHis: 0.736 ± 0.01	1.219HisIle: 1.219 ± 0.01	1.376HisLys: 1.376 ± 0.011	2.352HisLeu: 2.352 ± 0.014	0.487HisMet: 0.487 ± 0.006	1.006HisAsn: 1.006 ± 0.01	1.211HisPro: 1.211 ± 0.01	1.013HisGln: 1.013 ± 0.01	1.349HisArg: 1.349 ± 0.013	1.914HisSer: 1.914 ± 0.014	1.12HisThr: 1.12 ± 0.01	1.6HisVal: 1.6 ± 0.012	0.306HisTrp: 0.306 ± 0.005	0.8HisTyr: 0.8 ± 0.008	0.001HisXaa: 0.001 ± 0.0
Ile	3.369IleAla: 3.369 ± 0.018	1.14IleCys: 1.14 ± 0.01	2.889IleAsp: 2.889 ± 0.021	3.338IleGlu: 3.338 ± 0.019	2.038IlePhe: 2.038 ± 0.014	2.916IleGly: 2.916 ± 0.019	1.284IleHis: 1.284 ± 0.009	2.669IleIle: 2.669 ± 0.019	3.369IleLys: 3.369 ± 0.018	4.612IleLeu: 4.612 ± 0.023	1.019IleMet: 1.019 ± 0.01	2.349IleAsn: 2.349 ± 0.015	2.669IlePro: 2.669 ± 0.016	2.141IleGln: 2.141 ± 0.015	2.714IleArg: 2.714 ± 0.015	4.263IleSer: 4.263 ± 0.022	3.211IleThr: 3.211 ± 0.019	3.269IleVal: 3.269 ± 0.015	0.537IleTrp: 0.537 ± 0.007	1.444IleTyr: 1.444 ± 0.011	0.001IleXaa: 0.001 ± 0.0
Lys	4.476LysAla: 4.476 ± 0.024	1.467LysCys: 1.467 ± 0.014	4.03LysAsp: 4.03 ± 0.023	5.912LysGlu: 5.912 ± 0.035	2.406LysPhe: 2.406 ± 0.013	3.895LysGly: 3.895 ± 0.027	1.546LysHis: 1.546 ± 0.01	3.577LysIle: 3.577 ± 0.018	5.612LysLys: 5.612 ± 0.032	6.051LysLeu: 6.051 ± 0.026	1.495LysMet: 1.495 ± 0.013	3.085LysAsn: 3.085 ± 0.016	3.007LysPro: 3.007 ± 0.021	2.829LysGln: 2.829 ± 0.02	4.275LysArg: 4.275 ± 0.021	4.87LysSer: 4.87 ± 0.023	3.982LysThr: 3.982 ± 0.02	4.233LysVal: 4.233 ± 0.02	0.82LysTrp: 0.82 ± 0.008	1.979LysTyr: 1.979 ± 0.013	0.002LysXaa: 0.002 ± 0.0
Leu	5.599LeuAla: 5.599 ± 0.024	1.878LeuCys: 1.878 ± 0.016	4.736LeuAsp: 4.736 ± 0.024	6.381LeuGlu: 6.381 ± 0.041	3.48LeuPhe: 3.48 ± 0.02	4.997LeuGly: 4.997 ± 0.031	2.262LeuHis: 2.262 ± 0.014	4.066LeuIle: 4.066 ± 0.019	6.684LeuLys: 6.684 ± 0.032	8.451LeuLeu: 8.451 ± 0.064	1.834LeuMet: 1.834 ± 0.013	4.15LeuAsn: 4.15 ± 0.019	4.499LeuPro: 4.499 ± 0.021	4.337LeuGln: 4.337 ± 0.024	5.232LeuArg: 5.232 ± 0.023	7.481LeuSer: 7.481 ± 0.031	5.06LeuThr: 5.06 ± 0.024	5.366LeuVal: 5.366 ± 0.028	0.984LeuTrp: 0.984 ± 0.009	2.495LeuTyr: 2.495 ± 0.015	0.002LeuXaa: 0.002 ± 0.0
Met	1.738MetAla: 1.738 ± 0.012	0.379MetCys: 0.379 ± 0.005	1.189MetAsp: 1.189 ± 0.01	1.695MetGlu: 1.695 ± 0.013	0.852MetPhe: 0.852 ± 0.009	1.083MetGly: 1.083 ± 0.011	0.388MetHis: 0.388 ± 0.005	1.023MetIle: 1.023 ± 0.008	1.626MetLys: 1.626 ± 0.011	1.716MetLeu: 1.716 ± 0.012	0.521MetMet: 0.521 ± 0.007	0.956MetAsn: 0.956 ± 0.008	0.886MetPro: 0.886 ± 0.01	0.813MetGln: 0.813 ± 0.008	1.094MetArg: 1.094 ± 0.011	1.626MetSer: 1.626 ± 0.011	1.196MetThr: 1.196 ± 0.011	1.27MetVal: 1.27 ± 0.01	0.24MetTrp: 0.24 ± 0.004	0.595MetTyr: 0.595 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.735AsnAla: 2.735 ± 0.018	1.142AsnCys: 1.142 ± 0.014	2.533AsnAsp: 2.533 ± 0.019	3.067AsnGlu: 3.067 ± 0.02	1.908AsnPhe: 1.908 ± 0.013	3.279AsnGly: 3.279 ± 0.026	1.066AsnHis: 1.066 ± 0.01	2.652AsnIle: 2.652 ± 0.014	2.921AsnLys: 2.921 ± 0.018	4.177AsnLeu: 4.177 ± 0.023	0.962AsnMet: 0.962 ± 0.009	2.341AsnAsn: 2.341 ± 0.018	2.211AsnPro: 2.211 ± 0.015	1.785AsnGln: 1.785 ± 0.012	2.291AsnArg: 2.291 ± 0.014	3.824AsnSer: 3.824 ± 0.022	2.581AsnThr: 2.581 ± 0.017	3.019AsnVal: 3.019 ± 0.019	0.544AsnTrp: 0.544 ± 0.007	1.439AsnTyr: 1.439 ± 0.012	0.001AsnXaa: 0.001 ± 0.0
Pro	2.713ProAla: 2.713 ± 0.02	0.923ProCys: 0.923 ± 0.017	2.483ProAsp: 2.483 ± 0.018	3.068ProGlu: 3.068 ± 0.02	1.748ProPhe: 1.748 ± 0.01	2.962ProGly: 2.962 ± 0.041	1.017ProHis: 1.017 ± 0.008	1.97ProIle: 1.97 ± 0.013	2.809ProLys: 2.809 ± 0.018	4.014ProLeu: 4.014 ± 0.022	0.781ProMet: 0.781 ± 0.009	1.929ProAsn: 1.929 ± 0.013	3.276ProPro: 3.276 ± 0.035	1.909ProGln: 1.909 ± 0.016	2.377ProArg: 2.377 ± 0.017	4.348ProSer: 4.348 ± 0.027	2.825ProThr: 2.825 ± 0.024	3.296ProVal: 3.296 ± 0.019	0.545ProTrp: 0.545 ± 0.009	1.234ProTyr: 1.234 ± 0.012	0.002ProXaa: 0.002 ± 0.0
Gln	2.583GlnAla: 2.583 ± 0.017	0.828GlnCys: 0.828 ± 0.012	2.087GlnAsp: 2.087 ± 0.015	3.131GlnGlu: 3.131 ± 0.02	1.488GlnPhe: 1.488 ± 0.011	2.448GlnGly: 2.448 ± 0.02	1.014GlnHis: 1.014 ± 0.009	1.999GlnIle: 1.999 ± 0.011	2.654GlnLys: 2.654 ± 0.019	3.822GlnLeu: 3.822 ± 0.025	0.92GlnMet: 0.92 ± 0.009	1.876GlnAsn: 1.876 ± 0.014	1.809GlnPro: 1.809 ± 0.015	2.277GlnGln: 2.277 ± 0.024	2.571GlnArg: 2.571 ± 0.014	3.013GlnSer: 3.013 ± 0.018	2.253GlnThr: 2.253 ± 0.014	2.524GlnVal: 2.524 ± 0.015	0.559GlnTrp: 0.559 ± 0.012	1.112GlnTyr: 1.112 ± 0.011	0.001GlnXaa: 0.001 ± 0.0
Arg	3.154ArgAla: 3.154 ± 0.019	1.119ArgCys: 1.119 ± 0.013	2.957ArgAsp: 2.957 ± 0.017	4.059ArgGlu: 4.059 ± 0.066	2.098ArgPhe: 2.098 ± 0.016	3.228ArgGly: 3.228 ± 0.023	1.354ArgHis: 1.354 ± 0.011	2.796ArgIle: 2.796 ± 0.018	4.38ArgLys: 4.38 ± 0.021	4.892ArgLeu: 4.892 ± 0.022	1.134ArgMet: 1.134 ± 0.008	2.751ArgAsn: 2.751 ± 0.016	2.362ArgPro: 2.362 ± 0.019	2.335ArgGln: 2.335 ± 0.016	3.948ArgArg: 3.948 ± 0.045	4.077ArgSer: 4.077 ± 0.022	2.777ArgThr: 2.777 ± 0.017	3.298ArgVal: 3.298 ± 0.02	0.677ArgTrp: 0.677 ± 0.008	1.61ArgTyr: 1.61 ± 0.016	0.002ArgXaa: 0.002 ± 0.0
Ser	4.798SerAla: 4.798 ± 0.021	1.856SerCys: 1.856 ± 0.018	4.549SerAsp: 4.549 ± 0.022	5.12SerGlu: 5.12 ± 0.027	3.392SerPhe: 3.392 ± 0.017	5.164SerGly: 5.164 ± 0.03	1.856SerHis: 1.856 ± 0.014	3.699SerIle: 3.699 ± 0.019	5.051SerLys: 5.051 ± 0.023	7.566SerLeu: 7.566 ± 0.032	1.51SerMet: 1.51 ± 0.012	3.556SerAsn: 3.556 ± 0.021	4.157SerPro: 4.157 ± 0.029	3.229SerGln: 3.229 ± 0.017	4.192SerArg: 4.192 ± 0.026	8.792SerSer: 8.792 ± 0.073	4.795SerThr: 4.795 ± 0.025	5.268SerVal: 5.268 ± 0.024	0.971SerTrp: 0.971 ± 0.01	2.374SerTyr: 2.374 ± 0.017	0.003SerXaa: 0.003 ± 0.0
Thr	3.828ThrAla: 3.828 ± 0.027	1.37ThrCys: 1.37 ± 0.019	3.044ThrAsp: 3.044 ± 0.02	3.811ThrGlu: 3.811 ± 0.021	2.291ThrPhe: 2.291 ± 0.013	3.551ThrGly: 3.551 ± 0.025	1.146ThrHis: 1.146 ± 0.01	2.908ThrIle: 2.908 ± 0.017	3.665ThrLys: 3.665 ± 0.02	5.053ThrLeu: 5.053 ± 0.024	1.132ThrMet: 1.132 ± 0.01	2.471ThrAsn: 2.471 ± 0.017	3.007ThrPro: 3.007 ± 0.021	2.112ThrGln: 2.112 ± 0.015	2.795ThrArg: 2.795 ± 0.018	5.079ThrSer: 5.079 ± 0.027	3.741ThrThr: 3.741 ± 0.039	4.068ThrVal: 4.068 ± 0.023	0.685ThrTrp: 0.685 ± 0.008	1.515ThrTyr: 1.515 ± 0.012	0.002ThrXaa: 0.002 ± 0.0
Val	4.083ValAla: 4.083 ± 0.022	1.437ValCys: 1.437 ± 0.015	3.724ValAsp: 3.724 ± 0.02	4.383ValGlu: 4.383 ± 0.023	2.799ValPhe: 2.799 ± 0.017	3.423ValGly: 3.423 ± 0.022	1.524ValHis: 1.524 ± 0.012	3.566ValIle: 3.566 ± 0.023	4.42ValLys: 4.42 ± 0.024	5.879ValLeu: 5.879 ± 0.027	1.404ValMet: 1.404 ± 0.009	3.073ValAsn: 3.073 ± 0.02	2.952ValPro: 2.952 ± 0.018	2.595ValGln: 2.595 ± 0.016	3.228ValArg: 3.228 ± 0.019	5.007ValSer: 5.007 ± 0.023	4.233ValThr: 4.233 ± 0.025	4.553ValVal: 4.553 ± 0.025	0.73ValTrp: 0.73 ± 0.008	1.922ValTyr: 1.922 ± 0.013	0.002ValXaa: 0.002 ± 0.0
Trp	0.583TrpAla: 0.583 ± 0.007	0.282TrpCys: 0.282 ± 0.006	0.615TrpAsp: 0.615 ± 0.009	0.707TrpGlu: 0.707 ± 0.008	0.494TrpPhe: 0.494 ± 0.007	0.587TrpGly: 0.587 ± 0.008	0.273TrpHis: 0.273 ± 0.004	0.694TrpIle: 0.694 ± 0.008	1.013TrpLys: 1.013 ± 0.01	1.114TrpLeu: 1.114 ± 0.01	0.301TrpMet: 0.301 ± 0.005	0.66TrpAsn: 0.66 ± 0.007	0.447TrpPro: 0.447 ± 0.006	0.477TrpGln: 0.477 ± 0.007	0.748TrpArg: 0.748 ± 0.009	0.952TrpSer: 0.952 ± 0.01	0.709TrpThr: 0.709 ± 0.009	0.653TrpVal: 0.653 ± 0.009	0.207TrpTrp: 0.207 ± 0.004	0.397TrpTyr: 0.397 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.561TyrAla: 1.561 ± 0.013	0.735TyrCys: 0.735 ± 0.013	1.607TyrAsp: 1.607 ± 0.014	1.745TyrGlu: 1.745 ± 0.015	1.367TyrPhe: 1.367 ± 0.012	1.946TyrGly: 1.946 ± 0.018	0.874TyrHis: 0.874 ± 0.01	1.456TyrIle: 1.456 ± 0.011	1.862TyrLys: 1.862 ± 0.014	2.732TyrLeu: 2.732 ± 0.017	0.582TyrMet: 0.582 ± 0.007	1.398TyrAsn: 1.398 ± 0.011	1.218TyrPro: 1.218 ± 0.012	1.267TyrGln: 1.267 ± 0.011	1.701TyrArg: 1.701 ± 0.014	2.284TyrSer: 2.284 ± 0.017	1.585TyrThr: 1.585 ± 0.013	1.746TyrVal: 1.746 ± 0.014	0.415TyrTrp: 0.415 ± 0.006	1.079TyrTyr: 1.079 ± 0.028	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.002XaaAsp: 0.002 ± 0.0	0.002XaaGlu: 0.002 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.002XaaIle: 0.002 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.002XaaPro: 0.002 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.003XaaSer: 0.003 ± 0.0	0.002XaaThr: 0.002 ± 0.0	0.002XaaVal: 0.002 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.013XaaXaa: 0.013 ± 0.002

Statistics based on 24067 proteins (14677808 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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