Amino acid dipepetide frequency for Armadillidium vulgare (Pillbug) (Pill woodlouse)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.476AlaAla: 3.476 ± 0.039	0.893AlaCys: 0.893 ± 0.016	2.243AlaAsp: 2.243 ± 0.022	3.094AlaGlu: 3.094 ± 0.032	2.212AlaPhe: 2.212 ± 0.021	2.614AlaGly: 2.614 ± 0.031	1.075AlaHis: 1.075 ± 0.014	2.929AlaIle: 2.929 ± 0.024	3.274AlaLys: 3.274 ± 0.03	4.769AlaLeu: 4.769 ± 0.04	1.105AlaMet: 1.105 ± 0.016	2.317AlaAsn: 2.317 ± 0.02	2.166AlaPro: 2.166 ± 0.026	1.679AlaGln: 1.679 ± 0.02	2.148AlaArg: 2.148 ± 0.025	4.51AlaSer: 4.51 ± 0.04	2.737AlaThr: 2.737 ± 0.023	3.23AlaVal: 3.23 ± 0.027	0.459AlaTrp: 0.459 ± 0.01	1.45AlaTyr: 1.45 ± 0.016	0.0AlaXaa: 0.0 ± 0.0
Cys	0.828CysAla: 0.828 ± 0.014	0.506CysCys: 0.506 ± 0.014	1.178CysAsp: 1.178 ± 0.021	1.26CysGlu: 1.26 ± 0.022	0.95CysPhe: 0.95 ± 0.013	1.279CysGly: 1.279 ± 0.024	0.542CysHis: 0.542 ± 0.01	1.213CysIle: 1.213 ± 0.02	1.329CysLys: 1.329 ± 0.02	1.935CysLeu: 1.935 ± 0.02	0.386CysMet: 0.386 ± 0.009	1.067CysAsn: 1.067 ± 0.018	1.111CysPro: 1.111 ± 0.024	0.735CysGln: 0.735 ± 0.014	0.963CysArg: 0.963 ± 0.015	1.998CysSer: 1.998 ± 0.028	1.027CysThr: 1.027 ± 0.017	1.154CysVal: 1.154 ± 0.021	0.225CysTrp: 0.225 ± 0.007	0.659CysTyr: 0.659 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	2.437AspAla: 2.437 ± 0.025	0.998AspCys: 0.998 ± 0.02	3.595AspAsp: 3.595 ± 0.043	4.349AspGlu: 4.349 ± 0.039	2.554AspPhe: 2.554 ± 0.022	2.812AspGly: 2.812 ± 0.03	1.118AspHis: 1.118 ± 0.015	3.728AspIle: 3.728 ± 0.033	3.411AspLys: 3.411 ± 0.036	4.855AspLeu: 4.855 ± 0.028	1.123AspMet: 1.123 ± 0.014	2.587AspAsn: 2.587 ± 0.026	2.347AspPro: 2.347 ± 0.025	1.614AspGln: 1.614 ± 0.019	2.116AspArg: 2.116 ± 0.026	4.577AspSer: 4.577 ± 0.039	2.447AspThr: 2.447 ± 0.02	3.332AspVal: 3.332 ± 0.027	0.56AspTrp: 0.56 ± 0.011	1.83AspTyr: 1.83 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	3.69GluAla: 3.69 ± 0.032	1.26GluCys: 1.26 ± 0.024	4.547GluAsp: 4.547 ± 0.035	7.834GluGlu: 7.834 ± 0.08	2.498GluPhe: 2.498 ± 0.021	3.536GluGly: 3.536 ± 0.034	1.294GluHis: 1.294 ± 0.015	4.686GluIle: 4.686 ± 0.038	6.303GluLys: 6.303 ± 0.048	5.362GluLeu: 5.362 ± 0.038	1.627GluMet: 1.627 ± 0.016	4.883GluAsn: 4.883 ± 0.037	2.246GluPro: 2.246 ± 0.026	2.127GluGln: 2.127 ± 0.024	3.498GluArg: 3.498 ± 0.036	5.247GluSer: 5.247 ± 0.047	3.901GluThr: 3.901 ± 0.031	4.106GluVal: 4.106 ± 0.032	0.619GluTrp: 0.619 ± 0.012	2.101GluTyr: 2.101 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	1.971PheAla: 1.971 ± 0.02	1.054PheCys: 1.054 ± 0.014	2.417PheAsp: 2.417 ± 0.023	2.78PheGlu: 2.78 ± 0.025	2.04PhePhe: 2.04 ± 0.021	2.626PheGly: 2.626 ± 0.031	1.16PheHis: 1.16 ± 0.015	2.983PheIle: 2.983 ± 0.028	2.993PheLys: 2.993 ± 0.025	4.309PheLeu: 4.309 ± 0.035	0.985PheMet: 0.985 ± 0.013	2.287PheAsn: 2.287 ± 0.023	1.986PhePro: 1.986 ± 0.023	1.631PheGln: 1.631 ± 0.017	1.957PheArg: 1.957 ± 0.023	4.087PheSer: 4.087 ± 0.031	2.39PheThr: 2.39 ± 0.022	2.705PheVal: 2.705 ± 0.024	0.497PheTrp: 0.497 ± 0.009	1.695PheTyr: 1.695 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	2.639GlyAla: 2.639 ± 0.03	0.998GlyCys: 0.998 ± 0.021	2.598GlyAsp: 2.598 ± 0.042	3.388GlyGlu: 3.388 ± 0.03	2.504GlyPhe: 2.504 ± 0.03	4.412GlyGly: 4.412 ± 0.078	1.289GlyHis: 1.289 ± 0.019	3.452GlyIle: 3.452 ± 0.031	3.771GlyLys: 3.771 ± 0.031	4.273GlyLeu: 4.273 ± 0.042	1.203GlyMet: 1.203 ± 0.02	2.806GlyAsn: 2.806 ± 0.027	2.078GlyPro: 2.078 ± 0.041	1.692GlyGln: 1.692 ± 0.026	2.727GlyArg: 2.727 ± 0.029	4.772GlySer: 4.772 ± 0.043	2.956GlyThr: 2.956 ± 0.028	3.232GlyVal: 3.232 ± 0.032	0.589GlyTrp: 0.589 ± 0.011	1.867GlyTyr: 1.867 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	0.963HisAla: 0.963 ± 0.016	0.599HisCys: 0.599 ± 0.013	1.018HisAsp: 1.018 ± 0.014	1.338HisGlu: 1.338 ± 0.018	1.19HisPhe: 1.19 ± 0.015	1.151HisGly: 1.151 ± 0.018	0.911HisHis: 0.911 ± 0.018	1.556HisIle: 1.556 ± 0.016	1.462HisLys: 1.462 ± 0.017	2.566HisLeu: 2.566 ± 0.024	0.607HisMet: 0.607 ± 0.011	1.158HisAsn: 1.158 ± 0.016	1.353HisPro: 1.353 ± 0.019	1.038HisGln: 1.038 ± 0.018	1.198HisArg: 1.198 ± 0.018	2.259HisSer: 2.259 ± 0.026	1.253HisThr: 1.253 ± 0.018	1.246HisVal: 1.246 ± 0.015	0.271HisTrp: 0.271 ± 0.007	0.915HisTyr: 0.915 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	2.954IleAla: 2.954 ± 0.025	1.508IleCys: 1.508 ± 0.02	3.254IleAsp: 3.254 ± 0.027	4.152IleGlu: 4.152 ± 0.032	3.219IlePhe: 3.219 ± 0.031	3.104IleGly: 3.104 ± 0.029	1.536IleHis: 1.536 ± 0.018	4.168IleIle: 4.168 ± 0.034	4.571IleLys: 4.571 ± 0.036	6.125IleLeu: 6.125 ± 0.04	1.371IleMet: 1.371 ± 0.016	3.496IleAsn: 3.496 ± 0.028	3.213IlePro: 3.213 ± 0.031	2.24IleGln: 2.24 ± 0.023	2.777IleArg: 2.777 ± 0.021	5.632IleSer: 5.632 ± 0.033	3.369IleThr: 3.369 ± 0.024	3.443IleVal: 3.443 ± 0.026	0.629IleTrp: 0.629 ± 0.013	2.273IleTyr: 2.273 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	3.342LysAla: 3.342 ± 0.028	1.528LysCys: 1.528 ± 0.024	4.065LysAsp: 4.065 ± 0.035	6.439LysGlu: 6.439 ± 0.044	2.95LysPhe: 2.95 ± 0.027	3.507LysGly: 3.507 ± 0.06	1.658LysHis: 1.658 ± 0.019	4.915LysIle: 4.915 ± 0.038	6.845LysLys: 6.845 ± 0.063	6.236LysLeu: 6.236 ± 0.04	1.769LysMet: 1.769 ± 0.019	4.409LysAsn: 4.409 ± 0.035	2.943LysPro: 2.943 ± 0.033	2.363LysGln: 2.363 ± 0.023	4.065LysArg: 4.065 ± 0.032	5.877LysSer: 5.877 ± 0.057	3.937LysThr: 3.937 ± 0.03	4.066LysVal: 4.066 ± 0.03	0.713LysTrp: 0.713 ± 0.013	2.521LysTyr: 2.521 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	4.556LeuAla: 4.556 ± 0.038	1.881LeuCys: 1.881 ± 0.022	4.389LeuAsp: 4.389 ± 0.031	6.052LeuGlu: 6.052 ± 0.045	3.901LeuPhe: 3.901 ± 0.035	4.479LeuGly: 4.479 ± 0.037	2.379LeuHis: 2.379 ± 0.025	5.201LeuIle: 5.201 ± 0.039	7.375LeuLys: 7.375 ± 0.049	8.605LeuLeu: 8.605 ± 0.063	2.026LeuMet: 2.026 ± 0.02	4.95LeuAsn: 4.95 ± 0.037	4.7LeuPro: 4.7 ± 0.047	4.021LeuGln: 4.021 ± 0.033	4.69LeuArg: 4.69 ± 0.033	8.225LeuSer: 8.225 ± 0.067	4.844LeuThr: 4.844 ± 0.03	4.871LeuVal: 4.871 ± 0.032	0.914LeuTrp: 0.914 ± 0.014	2.872LeuTyr: 2.872 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	1.263MetAla: 1.263 ± 0.019	0.404MetCys: 0.404 ± 0.008	1.188MetAsp: 1.188 ± 0.015	1.658MetGlu: 1.658 ± 0.017	0.937MetPhe: 0.937 ± 0.014	1.197MetGly: 1.197 ± 0.022	0.418MetHis: 0.418 ± 0.008	1.35MetIle: 1.35 ± 0.016	1.985MetLys: 1.985 ± 0.023	1.8MetLeu: 1.8 ± 0.018	0.629MetMet: 0.629 ± 0.014	1.251MetAsn: 1.251 ± 0.017	0.899MetPro: 0.899 ± 0.012	0.758MetGln: 0.758 ± 0.012	1.049MetArg: 1.049 ± 0.014	1.777MetSer: 1.777 ± 0.018	1.198MetThr: 1.198 ± 0.015	1.239MetVal: 1.239 ± 0.015	0.225MetTrp: 0.225 ± 0.007	0.7MetTyr: 0.7 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.376AsnAla: 2.376 ± 0.023	1.114AsnCys: 1.114 ± 0.016	2.823AsnAsp: 2.823 ± 0.03	3.833AsnGlu: 3.833 ± 0.032	2.74AsnPhe: 2.74 ± 0.025	2.832AsnGly: 2.832 ± 0.031	1.276AsnHis: 1.276 ± 0.017	4.276AsnIle: 4.276 ± 0.033	3.828AsnLys: 3.828 ± 0.035	5.255AsnLeu: 5.255 ± 0.036	1.251AsnMet: 1.251 ± 0.016	3.392AsnAsn: 3.392 ± 0.042	2.485AsnPro: 2.485 ± 0.024	1.96AsnGln: 1.96 ± 0.023	2.272AsnArg: 2.272 ± 0.021	5.148AsnSer: 5.148 ± 0.041	2.757AsnThr: 2.757 ± 0.026	3.251AsnVal: 3.251 ± 0.026	0.528AsnTrp: 0.528 ± 0.01	1.968AsnTyr: 1.968 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	2.084ProAla: 2.084 ± 0.022	0.758ProCys: 0.758 ± 0.015	2.344ProAsp: 2.344 ± 0.025	3.107ProGlu: 3.107 ± 0.03	2.112ProPhe: 2.112 ± 0.03	2.391ProGly: 2.391 ± 0.049	1.238ProHis: 1.238 ± 0.022	2.612ProIle: 2.612 ± 0.038	3.269ProLys: 3.269 ± 0.032	4.377ProLeu: 4.377 ± 0.074	0.824ProMet: 0.824 ± 0.014	2.397ProAsn: 2.397 ± 0.025	3.985ProPro: 3.985 ± 0.086	1.933ProGln: 1.933 ± 0.027	2.069ProArg: 2.069 ± 0.027	5.044ProSer: 5.044 ± 0.049	2.753ProThr: 2.753 ± 0.032	2.93ProVal: 2.93 ± 0.03	0.456ProTrp: 0.456 ± 0.01	1.577ProTyr: 1.577 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	1.777GlnAla: 1.777 ± 0.02	0.721GlnCys: 0.721 ± 0.015	1.65GlnAsp: 1.65 ± 0.017	2.66GlnGlu: 2.66 ± 0.025	1.42GlnPhe: 1.42 ± 0.016	1.747GlnGly: 1.747 ± 0.021	0.978GlnHis: 0.978 ± 0.015	2.256GlnIle: 2.256 ± 0.023	2.741GlnLys: 2.741 ± 0.03	3.111GlnLeu: 3.111 ± 0.029	0.928GlnMet: 0.928 ± 0.013	2.384GlnAsn: 2.384 ± 0.024	1.669GlnPro: 1.669 ± 0.031	2.22GlnGln: 2.22 ± 0.047	2.002GlnArg: 2.002 ± 0.022	2.85GlnSer: 2.85 ± 0.033	2.022GlnThr: 2.022 ± 0.021	2.026GlnVal: 2.026 ± 0.019	0.343GlnTrp: 0.343 ± 0.009	1.194GlnTyr: 1.194 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	2.149ArgAla: 2.149 ± 0.023	0.908ArgCys: 0.908 ± 0.015	2.375ArgAsp: 2.375 ± 0.026	3.344ArgGlu: 3.344 ± 0.034	1.947ArgPhe: 1.947 ± 0.021	2.579ArgGly: 2.579 ± 0.033	1.285ArgHis: 1.285 ± 0.018	2.93ArgIle: 2.93 ± 0.023	4.23ArgLys: 4.23 ± 0.037	4.087ArgLeu: 4.087 ± 0.031	1.067ArgMet: 1.067 ± 0.015	2.831ArgAsn: 2.831 ± 0.023	2.131ArgPro: 2.131 ± 0.033	1.728ArgGln: 1.728 ± 0.02	3.411ArgArg: 3.411 ± 0.035	3.866ArgSer: 3.866 ± 0.039	2.412ArgThr: 2.412 ± 0.024	2.541ArgVal: 2.541 ± 0.022	0.501ArgTrp: 0.501 ± 0.01	1.539ArgTyr: 1.539 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	4.054SerAla: 4.054 ± 0.04	1.762SerCys: 1.762 ± 0.024	4.77SerAsp: 4.77 ± 0.041	5.813SerGlu: 5.813 ± 0.048	4.129SerPhe: 4.129 ± 0.029	4.71SerGly: 4.71 ± 0.043	2.234SerHis: 2.234 ± 0.026	4.929SerIle: 4.929 ± 0.033	6.074SerLys: 6.074 ± 0.044	8.613SerLeu: 8.613 ± 0.052	1.622SerMet: 1.622 ± 0.014	4.953SerAsn: 4.953 ± 0.044	5.057SerPro: 5.057 ± 0.085	3.455SerGln: 3.455 ± 0.035	4.026SerArg: 4.026 ± 0.038	11.502SerSer: 11.502 ± 0.139	5.219SerThr: 5.219 ± 0.067	5.227SerVal: 5.227 ± 0.04	0.802SerTrp: 0.802 ± 0.012	2.838SerTyr: 2.838 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	2.707ThrAla: 2.707 ± 0.025	1.113ThrCys: 1.113 ± 0.018	2.598ThrAsp: 2.598 ± 0.024	3.566ThrGlu: 3.566 ± 0.038	2.493ThrPhe: 2.493 ± 0.023	2.875ThrGly: 2.875 ± 0.029	1.29ThrHis: 1.29 ± 0.016	3.288ThrIle: 3.288 ± 0.025	3.572ThrLys: 3.572 ± 0.03	5.2ThrLeu: 5.2 ± 0.031	1.066ThrMet: 1.066 ± 0.017	2.71ThrAsn: 2.71 ± 0.024	3.232ThrPro: 3.232 ± 0.034	1.863ThrGln: 1.863 ± 0.022	2.238ThrArg: 2.238 ± 0.021	5.631ThrSer: 5.631 ± 0.063	3.634ThrThr: 3.634 ± 0.063	3.294ThrVal: 3.294 ± 0.028	0.505ThrTrp: 0.505 ± 0.01	1.685ThrTyr: 1.685 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	3.167ValAla: 3.167 ± 0.025	1.316ValCys: 1.316 ± 0.023	3.039ValAsp: 3.039 ± 0.029	3.925ValGlu: 3.925 ± 0.036	2.511ValPhe: 2.511 ± 0.026	2.99ValGly: 2.99 ± 0.031	1.315ValHis: 1.315 ± 0.016	3.663ValIle: 3.663 ± 0.027	4.12ValLys: 4.12 ± 0.032	5.329ValLeu: 5.329 ± 0.043	1.321ValMet: 1.321 ± 0.017	3.144ValAsn: 3.144 ± 0.024	2.796ValPro: 2.796 ± 0.029	2.045ValGln: 2.045 ± 0.022	2.561ValArg: 2.561 ± 0.025	5.159ValSer: 5.159 ± 0.034	3.512ValThr: 3.512 ± 0.032	3.686ValVal: 3.686 ± 0.029	0.573ValTrp: 0.573 ± 0.01	1.808ValTyr: 1.808 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.465TrpAla: 0.465 ± 0.01	0.212TrpCys: 0.212 ± 0.007	0.516TrpAsp: 0.516 ± 0.01	0.606TrpGlu: 0.606 ± 0.012	0.455TrpPhe: 0.455 ± 0.01	0.577TrpGly: 0.577 ± 0.012	0.233TrpHis: 0.233 ± 0.007	0.673TrpIle: 0.673 ± 0.012	0.812TrpLys: 0.812 ± 0.012	0.911TrpLeu: 0.911 ± 0.014	0.271TrpMet: 0.271 ± 0.007	0.586TrpAsn: 0.586 ± 0.012	0.354TrpPro: 0.354 ± 0.008	0.361TrpGln: 0.361 ± 0.009	0.551TrpArg: 0.551 ± 0.01	0.757TrpSer: 0.757 ± 0.011	0.553TrpThr: 0.553 ± 0.012	0.577TrpVal: 0.577 ± 0.011	0.151TrpTrp: 0.151 ± 0.006	0.31TrpTyr: 0.31 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.482TyrAla: 1.482 ± 0.02	0.812TyrCys: 0.812 ± 0.012	1.784TyrAsp: 1.784 ± 0.021	2.166TyrGlu: 2.166 ± 0.02	1.793TyrPhe: 1.793 ± 0.021	1.829TyrGly: 1.829 ± 0.023	0.824TyrHis: 0.824 ± 0.012	2.222TyrIle: 2.222 ± 0.031	2.184TyrLys: 2.184 ± 0.023	3.214TyrLeu: 3.214 ± 0.031	0.743TyrMet: 0.743 ± 0.013	1.758TyrAsn: 1.758 ± 0.019	1.511TyrPro: 1.511 ± 0.02	1.234TyrGln: 1.234 ± 0.016	1.54TyrArg: 1.54 ± 0.02	2.872TyrSer: 2.872 ± 0.028	1.64TyrThr: 1.64 ± 0.018	1.823TyrVal: 1.823 ± 0.02	0.371TyrTrp: 0.371 ± 0.009	1.361TyrTyr: 1.361 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.012XaaXaa: 0.012 ± 0.005

Statistics based on 18774 proteins (5621995 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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