Amino acid dipepetide frequency for Arundinibacter roseus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.576AlaAla: 6.576 ± 0.086	0.737AlaCys: 0.737 ± 0.022	4.239AlaAsp: 4.239 ± 0.051	4.8AlaGlu: 4.8 ± 0.059	3.639AlaPhe: 3.639 ± 0.051	6.046AlaGly: 6.046 ± 0.08	1.4AlaHis: 1.4 ± 0.035	4.562AlaIle: 4.562 ± 0.06	3.64AlaLys: 3.64 ± 0.058	7.825AlaLeu: 7.825 ± 0.089	1.739AlaMet: 1.739 ± 0.04	3.37AlaAsn: 3.37 ± 0.052	2.89AlaPro: 2.89 ± 0.051	3.563AlaGln: 3.563 ± 0.048	3.57AlaArg: 3.57 ± 0.048	4.451AlaSer: 4.451 ± 0.059	4.692AlaThr: 4.692 ± 0.089	4.909AlaVal: 4.909 ± 0.054	0.972AlaTrp: 0.972 ± 0.026	2.831AlaTyr: 2.831 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.566CysAla: 0.566 ± 0.024	0.119CysCys: 0.119 ± 0.009	0.417CysAsp: 0.417 ± 0.018	0.478CysGlu: 0.478 ± 0.023	0.414CysPhe: 0.414 ± 0.018	0.627CysGly: 0.627 ± 0.022	0.207CysHis: 0.207 ± 0.013	0.512CysIle: 0.512 ± 0.017	0.319CysLys: 0.319 ± 0.016	0.831CysLeu: 0.831 ± 0.027	0.189CysMet: 0.189 ± 0.01	0.314CysAsn: 0.314 ± 0.014	0.387CysPro: 0.387 ± 0.015	0.325CysGln: 0.325 ± 0.015	0.397CysArg: 0.397 ± 0.014	0.538CysSer: 0.538 ± 0.023	0.529CysThr: 0.529 ± 0.019	0.549CysVal: 0.549 ± 0.025	0.108CysTrp: 0.108 ± 0.009	0.276CysTyr: 0.276 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.911AspAla: 3.911 ± 0.059	0.395AspCys: 0.395 ± 0.017	2.322AspAsp: 2.322 ± 0.039	3.237AspGlu: 3.237 ± 0.049	3.239AspPhe: 3.239 ± 0.045	3.829AspGly: 3.829 ± 0.066	0.918AspHis: 0.918 ± 0.022	3.168AspIle: 3.168 ± 0.049	2.718AspLys: 2.718 ± 0.041	5.302AspLeu: 5.302 ± 0.06	1.145AspMet: 1.145 ± 0.027	2.065AspAsn: 2.065 ± 0.049	2.414AspPro: 2.414 ± 0.041	1.929AspGln: 1.929 ± 0.031	2.539AspArg: 2.539 ± 0.044	3.299AspSer: 3.299 ± 0.06	2.688AspThr: 2.688 ± 0.046	3.321AspVal: 3.321 ± 0.044	0.874AspTrp: 0.874 ± 0.023	2.321AspTyr: 2.321 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.727GluAla: 4.727 ± 0.058	0.347GluCys: 0.347 ± 0.016	2.705GluAsp: 2.705 ± 0.045	4.067GluGlu: 4.067 ± 0.063	2.65GluPhe: 2.65 ± 0.042	3.814GluGly: 3.814 ± 0.05	1.085GluHis: 1.085 ± 0.028	4.238GluIle: 4.238 ± 0.051	4.72GluLys: 4.72 ± 0.063	6.184GluLeu: 6.184 ± 0.076	1.587GluMet: 1.587 ± 0.034	3.35GluAsn: 3.35 ± 0.049	2.128GluPro: 2.128 ± 0.04	2.576GluGln: 2.576 ± 0.043	3.018GluArg: 3.018 ± 0.052	3.33GluSer: 3.33 ± 0.045	3.344GluThr: 3.344 ± 0.051	4.122GluVal: 4.122 ± 0.055	0.856GluTrp: 0.856 ± 0.027	2.055GluTyr: 2.055 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	3.283PheAla: 3.283 ± 0.042	0.494PheCys: 0.494 ± 0.018	3.005PheAsp: 3.005 ± 0.045	3.037PheGlu: 3.037 ± 0.044	2.591PhePhe: 2.591 ± 0.051	3.634PheGly: 3.634 ± 0.053	0.822PheHis: 0.822 ± 0.025	2.844PheIle: 2.844 ± 0.043	2.307PheLys: 2.307 ± 0.043	4.89PheLeu: 4.89 ± 0.07	1.148PheMet: 1.148 ± 0.027	2.174PheAsn: 2.174 ± 0.042	2.015PhePro: 2.015 ± 0.04	1.85PheGln: 1.85 ± 0.036	2.351PheArg: 2.351 ± 0.032	3.716PheSer: 3.716 ± 0.056	3.09PheThr: 3.09 ± 0.051	3.215PheVal: 3.215 ± 0.042	0.664PheTrp: 0.664 ± 0.022	1.852PheTyr: 1.852 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	4.906GlyAla: 4.906 ± 0.075	0.72GlyCys: 0.72 ± 0.031	3.357GlyAsp: 3.357 ± 0.061	3.682GlyGlu: 3.682 ± 0.055	3.645GlyPhe: 3.645 ± 0.055	5.158GlyGly: 5.158 ± 0.076	1.28GlyHis: 1.28 ± 0.032	4.975GlyIle: 4.975 ± 0.052	4.659GlyLys: 4.659 ± 0.058	6.967GlyLeu: 6.967 ± 0.085	1.855GlyMet: 1.855 ± 0.04	3.462GlyAsn: 3.462 ± 0.064	1.948GlyPro: 1.948 ± 0.04	2.807GlyGln: 2.807 ± 0.048	3.187GlyArg: 3.187 ± 0.051	4.609GlySer: 4.609 ± 0.067	4.541GlyThr: 4.541 ± 0.064	4.79GlyVal: 4.79 ± 0.062	1.082GlyTrp: 1.082 ± 0.029	2.912GlyTyr: 2.912 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	1.366HisAla: 1.366 ± 0.034	0.187HisCys: 0.187 ± 0.011	0.856HisAsp: 0.856 ± 0.026	1.099HisGlu: 1.099 ± 0.025	1.146HisPhe: 1.146 ± 0.03	1.215HisGly: 1.215 ± 0.031	0.491HisHis: 0.491 ± 0.019	1.128HisIle: 1.128 ± 0.032	0.852HisLys: 0.852 ± 0.026	1.896HisLeu: 1.896 ± 0.041	0.356HisMet: 0.356 ± 0.014	0.736HisAsn: 0.736 ± 0.023	1.088HisPro: 1.088 ± 0.034	0.855HisGln: 0.855 ± 0.025	0.993HisArg: 0.993 ± 0.027	1.197HisSer: 1.197 ± 0.028	1.098HisThr: 1.098 ± 0.026	1.129HisVal: 1.129 ± 0.029	0.294HisTrp: 0.294 ± 0.014	0.811HisTyr: 0.811 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	4.655IleAla: 4.655 ± 0.059	0.628IleCys: 0.628 ± 0.023	3.484IleAsp: 3.484 ± 0.058	3.993IleGlu: 3.993 ± 0.051	2.842IlePhe: 2.842 ± 0.049	4.542IleGly: 4.542 ± 0.061	1.252IleHis: 1.252 ± 0.03	3.527IleIle: 3.527 ± 0.051	3.354IleLys: 3.354 ± 0.051	6.047IleLeu: 6.047 ± 0.064	1.18IleMet: 1.18 ± 0.029	2.979IleAsn: 2.979 ± 0.048	3.107IlePro: 3.107 ± 0.046	2.701IleGln: 2.701 ± 0.04	3.463IleArg: 3.463 ± 0.049	4.678IleSer: 4.678 ± 0.057	3.586IleThr: 3.586 ± 0.054	3.763IleVal: 3.763 ± 0.047	0.677IleTrp: 0.677 ± 0.02	2.089IleTyr: 2.089 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	4.482LysAla: 4.482 ± 0.058	0.276LysCys: 0.276 ± 0.013	3.046LysAsp: 3.046 ± 0.056	3.928LysGlu: 3.928 ± 0.058	1.922LysPhe: 1.922 ± 0.036	3.794LysGly: 3.794 ± 0.058	0.955LysHis: 0.955 ± 0.025	3.924LysIle: 3.924 ± 0.056	4.308LysLys: 4.308 ± 0.059	4.954LysLeu: 4.954 ± 0.069	1.481LysMet: 1.481 ± 0.029	3.298LysAsn: 3.298 ± 0.056	2.521LysPro: 2.521 ± 0.043	2.098LysGln: 2.098 ± 0.039	2.471LysArg: 2.471 ± 0.041	3.382LysSer: 3.382 ± 0.042	3.453LysThr: 3.453 ± 0.044	3.703LysVal: 3.703 ± 0.049	0.691LysTrp: 0.691 ± 0.023	2.059LysTyr: 2.059 ± 0.037	0.0LysXaa: 0.0 ± 0.0
Leu	7.861LeuAla: 7.861 ± 0.087	0.826LeuCys: 0.826 ± 0.024	5.145LeuAsp: 5.145 ± 0.058	5.496LeuGlu: 5.496 ± 0.077	4.837LeuPhe: 4.837 ± 0.075	6.473LeuGly: 6.473 ± 0.073	2.032LeuHis: 2.032 ± 0.045	6.169LeuIle: 6.169 ± 0.072	5.605LeuLys: 5.605 ± 0.068	10.624LeuLeu: 10.624 ± 0.119	2.327LeuMet: 2.327 ± 0.036	4.919LeuAsn: 4.919 ± 0.059	5.078LeuPro: 5.078 ± 0.069	3.456LeuGln: 3.456 ± 0.056	4.911LeuArg: 4.911 ± 0.068	7.399LeuSer: 7.399 ± 0.074	6.544LeuThr: 6.544 ± 0.07	6.138LeuVal: 6.138 ± 0.069	1.139LeuTrp: 1.139 ± 0.03	3.334LeuTyr: 3.334 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	1.964MetAla: 1.964 ± 0.043	0.132MetCys: 0.132 ± 0.009	1.161MetAsp: 1.161 ± 0.027	1.362MetGlu: 1.362 ± 0.03	0.705MetPhe: 0.705 ± 0.02	1.66MetGly: 1.66 ± 0.037	0.455MetHis: 0.455 ± 0.016	1.374MetIle: 1.374 ± 0.029	1.863MetLys: 1.863 ± 0.036	2.146MetLeu: 2.146 ± 0.034	0.548MetMet: 0.548 ± 0.018	1.224MetAsn: 1.224 ± 0.029	1.082MetPro: 1.082 ± 0.026	1.067MetGln: 1.067 ± 0.025	1.079MetArg: 1.079 ± 0.025	1.371MetSer: 1.371 ± 0.029	1.255MetThr: 1.255 ± 0.027	1.333MetVal: 1.333 ± 0.027	0.228MetTrp: 0.228 ± 0.011	0.735MetTyr: 0.735 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.385AsnAla: 3.385 ± 0.056	0.342AsnCys: 0.342 ± 0.018	2.428AsnAsp: 2.428 ± 0.051	2.734AsnGlu: 2.734 ± 0.042	2.347AsnPhe: 2.347 ± 0.041	3.679AsnGly: 3.679 ± 0.073	0.927AsnHis: 0.927 ± 0.027	2.667AsnIle: 2.667 ± 0.042	2.202AsnLys: 2.202 ± 0.037	4.567AsnLeu: 4.567 ± 0.056	0.954AsnMet: 0.954 ± 0.022	2.205AsnAsn: 2.205 ± 0.042	3.016AsnPro: 3.016 ± 0.05	2.188AsnGln: 2.188 ± 0.042	2.627AsnArg: 2.627 ± 0.043	3.112AsnSer: 3.112 ± 0.051	2.764AsnThr: 2.764 ± 0.044	2.789AsnVal: 2.789 ± 0.05	0.688AsnTrp: 0.688 ± 0.02	2.061AsnTyr: 2.061 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	3.838ProAla: 3.838 ± 0.06	0.252ProCys: 0.252 ± 0.013	2.996ProAsp: 2.996 ± 0.048	3.441ProGlu: 3.441 ± 0.047	2.167ProPhe: 2.167 ± 0.036	3.155ProGly: 3.155 ± 0.054	0.829ProHis: 0.829 ± 0.024	2.623ProIle: 2.623 ± 0.039	2.157ProLys: 2.157 ± 0.042	3.947ProLeu: 3.947 ± 0.059	0.897ProMet: 0.897 ± 0.022	2.071ProAsn: 2.071 ± 0.037	1.406ProPro: 1.406 ± 0.037	1.699ProGln: 1.699 ± 0.031	1.618ProArg: 1.618 ± 0.033	2.542ProSer: 2.542 ± 0.038	2.772ProThr: 2.772 ± 0.057	3.252ProVal: 3.252 ± 0.051	0.519ProTrp: 0.519 ± 0.017	1.624ProTyr: 1.624 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.333GlnAla: 3.333 ± 0.046	0.238GlnCys: 0.238 ± 0.013	1.778GlnAsp: 1.778 ± 0.039	2.677GlnGlu: 2.677 ± 0.049	1.781GlnPhe: 1.781 ± 0.034	2.356GlnGly: 2.356 ± 0.038	0.751GlnHis: 0.751 ± 0.023	2.622GlnIle: 2.622 ± 0.041	2.984GlnLys: 2.984 ± 0.055	4.256GlnLeu: 4.256 ± 0.06	0.918GlnMet: 0.918 ± 0.023	2.133GlnAsn: 2.133 ± 0.037	1.861GlnPro: 1.861 ± 0.036	2.148GlnGln: 2.148 ± 0.038	2.056GlnArg: 2.056 ± 0.036	2.397GlnSer: 2.397 ± 0.042	2.579GlnThr: 2.579 ± 0.045	2.732GlnVal: 2.732 ± 0.036	0.593GlnTrp: 0.593 ± 0.018	1.353GlnTyr: 1.353 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	3.231ArgAla: 3.231 ± 0.049	0.296ArgCys: 0.296 ± 0.014	2.165ArgAsp: 2.165 ± 0.039	2.956ArgGlu: 2.956 ± 0.047	2.548ArgPhe: 2.548 ± 0.042	2.652ArgGly: 2.652 ± 0.049	0.904ArgHis: 0.904 ± 0.025	3.457ArgIle: 3.457 ± 0.046	2.939ArgLys: 2.939 ± 0.045	5.017ArgLeu: 5.017 ± 0.069	1.385ArgMet: 1.385 ± 0.03	2.4ArgAsn: 2.4 ± 0.045	1.943ArgPro: 1.943 ± 0.044	2.322ArgGln: 2.322 ± 0.04	2.429ArgArg: 2.429 ± 0.045	2.763ArgSer: 2.763 ± 0.051	2.821ArgThr: 2.821 ± 0.042	3.033ArgVal: 3.033 ± 0.043	0.723ArgTrp: 0.723 ± 0.024	2.151ArgTyr: 2.151 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	4.784SerAla: 4.784 ± 0.055	0.617SerCys: 0.617 ± 0.027	3.209SerAsp: 3.209 ± 0.044	3.708SerGlu: 3.708 ± 0.051	3.493SerPhe: 3.493 ± 0.05	5.128SerGly: 5.128 ± 0.081	1.103SerHis: 1.103 ± 0.026	4.123SerIle: 4.123 ± 0.057	3.139SerLys: 3.139 ± 0.047	6.736SerLeu: 6.736 ± 0.074	1.396SerMet: 1.396 ± 0.027	2.702SerAsn: 2.702 ± 0.051	2.944SerPro: 2.944 ± 0.051	2.446SerGln: 2.446 ± 0.042	2.959SerArg: 2.959 ± 0.047	4.101SerSer: 4.101 ± 0.064	3.856SerThr: 3.856 ± 0.07	4.276SerVal: 4.276 ± 0.063	0.926SerTrp: 0.926 ± 0.024	2.622SerTyr: 2.622 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	4.733ThrAla: 4.733 ± 0.08	0.445ThrCys: 0.445 ± 0.023	3.373ThrAsp: 3.373 ± 0.048	3.302ThrGlu: 3.302 ± 0.043	3.117ThrPhe: 3.117 ± 0.051	4.665ThrGly: 4.665 ± 0.066	1.168ThrHis: 1.168 ± 0.03	3.934ThrIle: 3.934 ± 0.066	2.676ThrLys: 2.676 ± 0.044	6.359ThrLeu: 6.359 ± 0.079	1.042ThrMet: 1.042 ± 0.026	2.814ThrAsn: 2.814 ± 0.058	3.056ThrPro: 3.056 ± 0.049	2.354ThrGln: 2.354 ± 0.041	2.521ThrArg: 2.521 ± 0.04	3.6ThrSer: 3.6 ± 0.055	3.924ThrThr: 3.924 ± 0.091	3.989ThrVal: 3.989 ± 0.089	0.751ThrTrp: 0.751 ± 0.025	2.487ThrTyr: 2.487 ± 0.049	0.0ThrXaa: 0.0 ± 0.0
Val	5.191ValAla: 5.191 ± 0.062	0.608ValCys: 0.608 ± 0.022	3.207ValAsp: 3.207 ± 0.05	3.853ValGlu: 3.853 ± 0.058	3.103ValPhe: 3.103 ± 0.041	4.518ValGly: 4.518 ± 0.063	1.169ValHis: 1.169 ± 0.028	3.832ValIle: 3.832 ± 0.051	3.519ValLys: 3.519 ± 0.046	6.472ValLeu: 6.472 ± 0.066	1.453ValMet: 1.453 ± 0.028	2.976ValAsn: 2.976 ± 0.053	2.832ValPro: 2.832 ± 0.04	2.729ValGln: 2.729 ± 0.037	3.23ValArg: 3.23 ± 0.052	4.568ValSer: 4.568 ± 0.064	3.664ValThr: 3.664 ± 0.087	4.824ValVal: 4.824 ± 0.056	0.893ValTrp: 0.893 ± 0.027	2.367ValTyr: 2.367 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	0.945TrpAla: 0.945 ± 0.026	0.099TrpCys: 0.099 ± 0.008	0.663TrpAsp: 0.663 ± 0.021	0.789TrpGlu: 0.789 ± 0.023	0.634TrpPhe: 0.634 ± 0.02	0.925TrpGly: 0.925 ± 0.024	0.295TrpHis: 0.295 ± 0.013	0.8TrpIle: 0.8 ± 0.021	0.884TrpLys: 0.884 ± 0.026	1.401TrpLeu: 1.401 ± 0.035	0.402TrpMet: 0.402 ± 0.017	0.756TrpAsn: 0.756 ± 0.022	0.407TrpPro: 0.407 ± 0.016	0.714TrpGln: 0.714 ± 0.022	0.622TrpArg: 0.622 ± 0.022	0.756TrpSer: 0.756 ± 0.028	0.764TrpThr: 0.764 ± 0.022	0.869TrpVal: 0.869 ± 0.023	0.221TrpTrp: 0.221 ± 0.014	0.518TrpTyr: 0.518 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.716TyrAla: 2.716 ± 0.041	0.343TyrCys: 0.343 ± 0.015	2.078TyrAsp: 2.078 ± 0.042	2.263TyrGlu: 2.263 ± 0.039	2.161TyrPhe: 2.161 ± 0.04	2.671TyrGly: 2.671 ± 0.048	0.751TyrHis: 0.751 ± 0.023	2.069TyrIle: 2.069 ± 0.035	1.905TyrLys: 1.905 ± 0.036	3.891TyrLeu: 3.891 ± 0.061	0.741TyrMet: 0.741 ± 0.02	1.736TyrAsn: 1.736 ± 0.041	1.68TyrPro: 1.68 ± 0.035	1.718TyrGln: 1.718 ± 0.029	2.093TyrArg: 2.093 ± 0.039	2.458TyrSer: 2.458 ± 0.04	2.348TyrThr: 2.348 ± 0.047	2.272TyrVal: 2.272 ± 0.035	0.564TyrTrp: 0.564 ± 0.021	1.565TyrTyr: 1.565 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4679 proteins (1707330 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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