Amino acid dipepetide frequency for Candida tenuis (strain ATCC 10573 / BCRC 21748 / CBS 615 / JCM 9827 / NBRC 10315 / NRRL Y-1498 / VKM Y-70) (Yeast) (Yamadazyma tenuis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.18AlaAla: 4.18 ± 0.056
0.688AlaCys: 0.688 ± 0.017
2.859AlaAsp: 2.859 ± 0.035
3.053AlaGlu: 3.053 ± 0.04
2.432AlaPhe: 2.432 ± 0.037
3.267AlaGly: 3.267 ± 0.046
1.128AlaHis: 1.128 ± 0.021
3.796AlaIle: 3.796 ± 0.047
3.846AlaLys: 3.846 ± 0.044
5.194AlaLeu: 5.194 ± 0.054
1.159AlaMet: 1.159 ± 0.022
3.035AlaAsn: 3.035 ± 0.032
2.459AlaPro: 2.459 ± 0.03
1.99AlaGln: 1.99 ± 0.033
2.355AlaArg: 2.355 ± 0.033
5.076AlaSer: 5.076 ± 0.051
3.317AlaThr: 3.317 ± 0.038
3.678AlaVal: 3.678 ± 0.04
0.536AlaTrp: 0.536 ± 0.014
1.831AlaTyr: 1.831 ± 0.029
0.0AlaXaa: 0.0 ± 0.0
Cys
0.578CysAla: 0.578 ± 0.016
0.253CysCys: 0.253 ± 0.01
0.629CysAsp: 0.629 ± 0.019
0.593CysGlu: 0.593 ± 0.015
0.69CysPhe: 0.69 ± 0.017
0.842CysGly: 0.842 ± 0.019
0.298CysHis: 0.298 ± 0.011
0.821CysIle: 0.821 ± 0.017
0.688CysLys: 0.688 ± 0.017
1.275CysLeu: 1.275 ± 0.023
0.232CysMet: 0.232 ± 0.009
0.548CysAsn: 0.548 ± 0.013
0.465CysPro: 0.465 ± 0.013
0.394CysGln: 0.394 ± 0.012
0.424CysArg: 0.424 ± 0.013
0.97CysSer: 0.97 ± 0.021
0.554CysThr: 0.554 ± 0.015
0.744CysVal: 0.744 ± 0.02
0.165CysTrp: 0.165 ± 0.008
0.462CysTyr: 0.462 ± 0.014
0.0CysXaa: 0.0 ± 0.0
Asp
3.031AspAla: 3.031 ± 0.033
0.575AspCys: 0.575 ± 0.014
4.544AspAsp: 4.544 ± 0.059
4.813AspGlu: 4.813 ± 0.051
3.041AspPhe: 3.041 ± 0.032
2.938AspGly: 2.938 ± 0.037
1.252AspHis: 1.252 ± 0.025
4.165AspIle: 4.165 ± 0.043
3.738AspLys: 3.738 ± 0.047
6.052AspLeu: 6.052 ± 0.049
1.165AspMet: 1.165 ± 0.019
3.007AspAsn: 3.007 ± 0.031
2.613AspPro: 2.613 ± 0.034
1.996AspGln: 1.996 ± 0.027
2.001AspArg: 2.001 ± 0.031
5.103AspSer: 5.103 ± 0.053
3.068AspThr: 3.068 ± 0.036
3.585AspVal: 3.585 ± 0.035
0.66AspTrp: 0.66 ± 0.016
2.426AspTyr: 2.426 ± 0.033
0.0AspXaa: 0.0 ± 0.0
Glu
3.556GluAla: 3.556 ± 0.046
0.602GluCys: 0.602 ± 0.015
4.24GluAsp: 4.24 ± 0.047
5.094GluGlu: 5.094 ± 0.064
3.112GluPhe: 3.112 ± 0.033
2.729GluGly: 2.729 ± 0.034
1.207GluHis: 1.207 ± 0.021
4.19GluIle: 4.19 ± 0.048
4.275GluLys: 4.275 ± 0.042
6.365GluLeu: 6.365 ± 0.055
1.375GluMet: 1.375 ± 0.024
3.36GluAsn: 3.36 ± 0.039
2.098GluPro: 2.098 ± 0.033
2.295GluGln: 2.295 ± 0.026
2.557GluArg: 2.557 ± 0.033
4.889GluSer: 4.889 ± 0.051
3.361GluThr: 3.361 ± 0.036
3.885GluVal: 3.885 ± 0.042
0.625GluTrp: 0.625 ± 0.016
2.364GluTyr: 2.364 ± 0.031
0.0GluXaa: 0.0 ± 0.0
Phe
2.575PheAla: 2.575 ± 0.038
0.553PheCys: 0.553 ± 0.016
3.101PheAsp: 3.101 ± 0.029
3.063PheGlu: 3.063 ± 0.037
2.269PhePhe: 2.269 ± 0.034
3.033PheGly: 3.033 ± 0.037
1.064PheHis: 1.064 ± 0.021
3.076PheIle: 3.076 ± 0.038
3.539PheLys: 3.539 ± 0.042
4.315PheLeu: 4.315 ± 0.049
0.996PheMet: 0.996 ± 0.019
3.117PheAsn: 3.117 ± 0.043
1.894PhePro: 1.894 ± 0.03
1.781PheGln: 1.781 ± 0.025
1.72PheArg: 1.72 ± 0.028
3.822PheSer: 3.822 ± 0.039
2.617PheThr: 2.617 ± 0.035
3.077PheVal: 3.077 ± 0.037
0.594PheTrp: 0.594 ± 0.015
1.734PheTyr: 1.734 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
3.215GlyAla: 3.215 ± 0.045
0.778GlyCys: 0.778 ± 0.018
3.06GlyAsp: 3.06 ± 0.035
2.938GlyGlu: 2.938 ± 0.033
2.909GlyPhe: 2.909 ± 0.04
3.596GlyGly: 3.596 ± 0.054
1.219GlyHis: 1.219 ± 0.024
3.703GlyIle: 3.703 ± 0.044
3.507GlyLys: 3.507 ± 0.044
5.274GlyLeu: 5.274 ± 0.05
1.042GlyMet: 1.042 ± 0.02
2.64GlyAsn: 2.64 ± 0.03
1.857GlyPro: 1.857 ± 0.031
1.706GlyGln: 1.706 ± 0.03
2.126GlyArg: 2.126 ± 0.034
4.864GlySer: 4.864 ± 0.053
3.016GlyThr: 3.016 ± 0.039
3.673GlyVal: 3.673 ± 0.045
0.694GlyTrp: 0.694 ± 0.017
2.155GlyTyr: 2.155 ± 0.032
0.0GlyXaa: 0.0 ± 0.0
His
0.928HisAla: 0.928 ± 0.02
0.266HisCys: 0.266 ± 0.011
1.231HisAsp: 1.231 ± 0.02
1.345HisGlu: 1.345 ± 0.021
1.006HisPhe: 1.006 ± 0.022
1.198HisGly: 1.198 ± 0.022
0.765HisHis: 0.765 ± 0.024
1.409HisIle: 1.409 ± 0.024
1.467HisLys: 1.467 ± 0.023
2.232HisLeu: 2.232 ± 0.028
0.421HisMet: 0.421 ± 0.013
1.164HisAsn: 1.164 ± 0.02
1.19HisPro: 1.19 ± 0.022
1.097HisGln: 1.097 ± 0.023
1.033HisArg: 1.033 ± 0.022
1.884HisSer: 1.884 ± 0.029
1.13HisThr: 1.13 ± 0.021
1.182HisVal: 1.182 ± 0.023
0.232HisTrp: 0.232 ± 0.01
0.87HisTyr: 0.87 ± 0.02
0.0HisXaa: 0.0 ± 0.0
Ile
3.525IleAla: 3.525 ± 0.047
0.842IleCys: 0.842 ± 0.017
4.35IleAsp: 4.35 ± 0.044
4.11IleGlu: 4.11 ± 0.038
2.846IlePhe: 2.846 ± 0.043
3.574IleGly: 3.574 ± 0.043
1.457IleHis: 1.457 ± 0.025
4.143IleIle: 4.143 ± 0.05
4.646IleLys: 4.646 ± 0.044
6.121IleLeu: 6.121 ± 0.065
1.302IleMet: 1.302 ± 0.022
4.229IleAsn: 4.229 ± 0.047
3.232IlePro: 3.232 ± 0.035
2.327IleGln: 2.327 ± 0.027
2.717IleArg: 2.717 ± 0.033
5.683IleSer: 5.683 ± 0.047
3.697IleThr: 3.697 ± 0.038
3.903IleVal: 3.903 ± 0.038
0.701IleTrp: 0.701 ± 0.017
2.226IleTyr: 2.226 ± 0.029
0.0IleXaa: 0.0 ± 0.0
Lys
3.737LysAla: 3.737 ± 0.05
0.681LysCys: 0.681 ± 0.014
4.047LysAsp: 4.047 ± 0.047
4.286LysGlu: 4.286 ± 0.05
3.389LysPhe: 3.389 ± 0.04
2.921LysGly: 2.921 ± 0.034
1.582LysHis: 1.582 ± 0.027
4.4LysIle: 4.4 ± 0.046
5.332LysLys: 5.332 ± 0.066
7.269LysLeu: 7.269 ± 0.066
1.307LysMet: 1.307 ± 0.022
3.763LysAsn: 3.763 ± 0.035
3.04LysPro: 3.04 ± 0.037
2.792LysGln: 2.792 ± 0.034
3.367LysArg: 3.367 ± 0.044
5.731LysSer: 5.731 ± 0.052
3.688LysThr: 3.688 ± 0.042
4.29LysVal: 4.29 ± 0.045
0.732LysTrp: 0.732 ± 0.018
2.792LysTyr: 2.792 ± 0.036
0.0LysXaa: 0.0 ± 0.0
Leu
5.649LeuAla: 5.649 ± 0.052
1.155LeuCys: 1.155 ± 0.022
5.527LeuAsp: 5.527 ± 0.044
5.816LeuGlu: 5.816 ± 0.058
4.212LeuPhe: 4.212 ± 0.044
5.196LeuGly: 5.196 ± 0.055
2.054LeuHis: 2.054 ± 0.029
6.298LeuIle: 6.298 ± 0.073
7.084LeuLys: 7.084 ± 0.067
8.914LeuLeu: 8.914 ± 0.072
2.129LeuMet: 2.129 ± 0.031
6.029LeuAsn: 6.029 ± 0.061
4.51LeuPro: 4.51 ± 0.045
3.816LeuGln: 3.816 ± 0.038
4.095LeuArg: 4.095 ± 0.04
8.593LeuSer: 8.593 ± 0.063
5.431LeuThr: 5.431 ± 0.052
6.549LeuVal: 6.549 ± 0.06
0.877LeuTrp: 0.877 ± 0.02
3.136LeuTyr: 3.136 ± 0.041
0.0LeuXaa: 0.0 ± 0.0
Met
1.481MetAla: 1.481 ± 0.027
0.25MetCys: 0.25 ± 0.01
1.146MetAsp: 1.146 ± 0.02
1.203MetGlu: 1.203 ± 0.022
0.966MetPhe: 0.966 ± 0.02
1.214MetGly: 1.214 ± 0.023
0.309MetHis: 0.309 ± 0.01
1.275MetIle: 1.275 ± 0.025
1.425MetLys: 1.425 ± 0.024
1.784MetLeu: 1.784 ± 0.027
0.507MetMet: 0.507 ± 0.013
1.246MetAsn: 1.246 ± 0.026
0.757MetPro: 0.757 ± 0.018
0.519MetGln: 0.519 ± 0.015
0.77MetArg: 0.77 ± 0.019
2.111MetSer: 2.111 ± 0.024
1.096MetThr: 1.096 ± 0.022
1.428MetVal: 1.428 ± 0.021
0.187MetTrp: 0.187 ± 0.009
0.645MetTyr: 0.645 ± 0.016
0.0MetXaa: 0.0 ± 0.0
Asn
2.712AsnAla: 2.712 ± 0.027
0.653AsnCys: 0.653 ± 0.017
3.614AsnAsp: 3.614 ± 0.044
3.641AsnGlu: 3.641 ± 0.045
2.735AsnPhe: 2.735 ± 0.035
3.193AsnGly: 3.193 ± 0.04
1.428AsnHis: 1.428 ± 0.023
3.572AsnIle: 3.572 ± 0.036
3.777AsnLys: 3.777 ± 0.044
5.78AsnLeu: 5.78 ± 0.066
1.08AsnMet: 1.08 ± 0.023
3.441AsnAsn: 3.441 ± 0.051
2.68AsnPro: 2.68 ± 0.034
2.228AsnGln: 2.228 ± 0.031
2.042AsnArg: 2.042 ± 0.029
5.205AsnSer: 5.205 ± 0.063
2.909AsnThr: 2.909 ± 0.038
3.027AsnVal: 3.027 ± 0.035
0.669AsnTrp: 0.669 ± 0.015
2.393AsnTyr: 2.393 ± 0.035
0.0AsnXaa: 0.0 ± 0.0
Pro
2.384ProAla: 2.384 ± 0.035
0.34ProCys: 0.34 ± 0.014
2.405ProAsp: 2.405 ± 0.038
3.136ProGlu: 3.136 ± 0.034
2.0ProPhe: 2.0 ± 0.03
2.212ProGly: 2.212 ± 0.034
0.991ProHis: 0.991 ± 0.022
2.902ProIle: 2.902 ± 0.035
3.053ProLys: 3.053 ± 0.033
3.793ProLeu: 3.793 ± 0.039
0.796ProMet: 0.796 ± 0.017
2.426ProAsn: 2.426 ± 0.035
2.437ProPro: 2.437 ± 0.048
1.977ProGln: 1.977 ± 0.034
1.689ProArg: 1.689 ± 0.028
4.141ProSer: 4.141 ± 0.047
2.789ProThr: 2.789 ± 0.037
3.067ProVal: 3.067 ± 0.035
0.423ProTrp: 0.423 ± 0.013
1.426ProTyr: 1.426 ± 0.028
0.0ProXaa: 0.0 ± 0.0
Gln
2.08GlnAla: 2.08 ± 0.034
0.356GlnCys: 0.356 ± 0.012
1.957GlnAsp: 1.957 ± 0.026
2.389GlnGlu: 2.389 ± 0.035
1.91GlnPhe: 1.91 ± 0.027
1.663GlnGly: 1.663 ± 0.025
0.85GlnHis: 0.85 ± 0.02
2.476GlnIle: 2.476 ± 0.033
2.458GlnLys: 2.458 ± 0.032
4.069GlnLeu: 4.069 ± 0.046
0.908GlnMet: 0.908 ± 0.022
1.937GlnAsn: 1.937 ± 0.029
1.644GlnPro: 1.644 ± 0.03
2.094GlnGln: 2.094 ± 0.05
1.619GlnArg: 1.619 ± 0.03
2.996GlnSer: 2.996 ± 0.042
2.019GlnThr: 2.019 ± 0.028
2.39GlnVal: 2.39 ± 0.03
0.416GlnTrp: 0.416 ± 0.013
1.454GlnTyr: 1.454 ± 0.024
0.0GlnXaa: 0.0 ± 0.0
Arg
2.297ArgAla: 2.297 ± 0.032
0.512ArgCys: 0.512 ± 0.015
2.242ArgAsp: 2.242 ± 0.03
2.342ArgGlu: 2.342 ± 0.032
2.152ArgPhe: 2.152 ± 0.027
2.08ArgGly: 2.08 ± 0.029
0.933ArgHis: 0.933 ± 0.018
2.696ArgIle: 2.696 ± 0.033
3.007ArgLys: 3.007 ± 0.042
4.193ArgLeu: 4.193 ± 0.045
0.851ArgMet: 0.851 ± 0.02
2.218ArgAsn: 2.218 ± 0.028
1.672ArgPro: 1.672 ± 0.026
1.623ArgGln: 1.623 ± 0.028
2.444ArgArg: 2.444 ± 0.037
3.439ArgSer: 3.439 ± 0.045
2.159ArgThr: 2.159 ± 0.03
2.511ArgVal: 2.511 ± 0.035
0.465ArgTrp: 0.465 ± 0.015
1.499ArgTyr: 1.499 ± 0.023
0.0ArgXaa: 0.0 ± 0.0
Ser
4.598SerAla: 4.598 ± 0.049
0.883SerCys: 0.883 ± 0.021
4.873SerAsp: 4.873 ± 0.045
4.718SerGlu: 4.718 ± 0.044
4.192SerPhe: 4.192 ± 0.042
4.696SerGly: 4.696 ± 0.047
1.983SerHis: 1.983 ± 0.027
6.114SerIle: 6.114 ± 0.056
6.091SerLys: 6.091 ± 0.058
8.416SerLeu: 8.416 ± 0.071
1.824SerMet: 1.824 ± 0.029
5.135SerAsn: 5.135 ± 0.053
3.987SerPro: 3.987 ± 0.06
3.319SerGln: 3.319 ± 0.039
3.724SerArg: 3.724 ± 0.042
9.512SerSer: 9.512 ± 0.107
5.498SerThr: 5.498 ± 0.047
5.404SerVal: 5.404 ± 0.044
0.903SerTrp: 0.903 ± 0.019
2.873SerTyr: 2.873 ± 0.032
0.0SerXaa: 0.0 ± 0.0
Thr
3.186ThrAla: 3.186 ± 0.035
0.677ThrCys: 0.677 ± 0.013
2.951ThrAsp: 2.951 ± 0.032
2.939ThrGlu: 2.939 ± 0.035
2.495ThrPhe: 2.495 ± 0.03
3.29ThrGly: 3.29 ± 0.04
1.138ThrHis: 1.138 ± 0.023
3.811ThrIle: 3.811 ± 0.041
3.878ThrLys: 3.878 ± 0.043
5.046ThrLeu: 5.046 ± 0.045
1.018ThrMet: 1.018 ± 0.02
3.211ThrAsn: 3.211 ± 0.038
3.059ThrPro: 3.059 ± 0.042
1.836ThrGln: 1.836 ± 0.029
2.323ThrArg: 2.323 ± 0.028
5.333ThrSer: 5.333 ± 0.044
3.424ThrThr: 3.424 ± 0.043
3.437ThrVal: 3.437 ± 0.036
0.557ThrTrp: 0.557 ± 0.015
1.814ThrTyr: 1.814 ± 0.032
0.0ThrXaa: 0.0 ± 0.0
Val
3.819ValAla: 3.819 ± 0.052
0.817ValCys: 0.817 ± 0.019
4.036ValAsp: 4.036 ± 0.036
3.915ValGlu: 3.915 ± 0.042
3.109ValPhe: 3.109 ± 0.037
3.543ValGly: 3.543 ± 0.045
1.279ValHis: 1.279 ± 0.023
3.929ValIle: 3.929 ± 0.036
4.149ValLys: 4.149 ± 0.042
6.137ValLeu: 6.137 ± 0.057
1.253ValMet: 1.253 ± 0.025
3.443ValAsn: 3.443 ± 0.035
3.01ValPro: 3.01 ± 0.04
2.073ValGln: 2.073 ± 0.031
2.368ValArg: 2.368 ± 0.027
5.548ValSer: 5.548 ± 0.043
3.246ValThr: 3.246 ± 0.039
4.465ValVal: 4.465 ± 0.048
0.699ValTrp: 0.699 ± 0.018
2.19ValTyr: 2.19 ± 0.027
0.0ValXaa: 0.0 ± 0.0
Trp
0.577TrpAla: 0.577 ± 0.016
0.23TrpCys: 0.23 ± 0.009
0.665TrpAsp: 0.665 ± 0.017
0.627TrpGlu: 0.627 ± 0.017
0.581TrpPhe: 0.581 ± 0.013
0.619TrpGly: 0.619 ± 0.016
0.218TrpHis: 0.218 ± 0.01
0.671TrpIle: 0.671 ± 0.016
0.772TrpLys: 0.772 ± 0.017
1.05TrpLeu: 1.05 ± 0.019
0.228TrpMet: 0.228 ± 0.009
0.638TrpAsn: 0.638 ± 0.016
0.322TrpPro: 0.322 ± 0.012
0.314TrpGln: 0.314 ± 0.01
0.521TrpArg: 0.521 ± 0.013
0.886TrpSer: 0.886 ± 0.019
0.535TrpThr: 0.535 ± 0.016
0.674TrpVal: 0.674 ± 0.015
0.177TrpTrp: 0.177 ± 0.009
0.445TrpTyr: 0.445 ± 0.013
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.769TyrAla: 1.769 ± 0.023
0.517TyrCys: 0.517 ± 0.014
2.297TyrAsp: 2.297 ± 0.031
2.158TyrGlu: 2.158 ± 0.029
1.891TyrPhe: 1.891 ± 0.025
2.17TyrGly: 2.17 ± 0.03
0.894TyrHis: 0.894 ± 0.018
2.185TyrIle: 2.185 ± 0.031
2.415TyrLys: 2.415 ± 0.031
3.791TyrLeu: 3.791 ± 0.04
0.722TyrMet: 0.722 ± 0.018
2.192TyrAsn: 2.192 ± 0.034
1.461TyrPro: 1.461 ± 0.025
1.512TyrGln: 1.512 ± 0.025
1.442TyrArg: 1.442 ± 0.025
2.957TyrSer: 2.957 ± 0.035
1.869TyrThr: 1.869 ± 0.027
2.058TyrVal: 2.058 ± 0.031
0.438TyrTrp: 0.438 ± 0.012
1.552TyrTyr: 1.552 ± 0.026
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6051 proteins (2636551 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski