Amino acid dipepetide frequency for Oleiagrimonas soli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.728AlaAla: 15.728 ± 0.212
1.237AlaCys: 1.237 ± 0.044
7.21AlaAsp: 7.21 ± 0.105
6.603AlaGlu: 6.603 ± 0.12
4.063AlaPhe: 4.063 ± 0.077
9.729AlaGly: 9.729 ± 0.184
3.208AlaHis: 3.208 ± 0.063
5.015AlaIle: 5.015 ± 0.089
3.431AlaLys: 3.431 ± 0.082
14.889AlaLeu: 14.889 ± 0.171
3.517AlaMet: 3.517 ± 0.072
2.692AlaAsn: 2.692 ± 0.064
5.692AlaPro: 5.692 ± 0.096
5.147AlaGln: 5.147 ± 0.105
9.184AlaArg: 9.184 ± 0.15
6.679AlaSer: 6.679 ± 0.109
5.697AlaThr: 5.697 ± 0.103
8.39AlaVal: 8.39 ± 0.109
2.077AlaTrp: 2.077 ± 0.06
2.643AlaTyr: 2.643 ± 0.06
0.0AlaXaa: 0.0 ± 0.0
Cys
1.093CysAla: 1.093 ± 0.038
0.116CysCys: 0.116 ± 0.012
0.496CysAsp: 0.496 ± 0.025
0.485CysGlu: 0.485 ± 0.026
0.266CysPhe: 0.266 ± 0.016
0.915CysGly: 0.915 ± 0.037
0.244CysHis: 0.244 ± 0.018
0.333CysIle: 0.333 ± 0.02
0.207CysLys: 0.207 ± 0.016
0.861CysLeu: 0.861 ± 0.037
0.208CysMet: 0.208 ± 0.015
0.227CysAsn: 0.227 ± 0.016
0.434CysPro: 0.434 ± 0.022
0.222CysGln: 0.222 ± 0.017
0.628CysArg: 0.628 ± 0.033
0.456CysSer: 0.456 ± 0.027
0.447CysThr: 0.447 ± 0.024
0.772CysVal: 0.772 ± 0.031
0.121CysTrp: 0.121 ± 0.012
0.217CysTyr: 0.217 ± 0.016
0.0CysXaa: 0.0 ± 0.0
Asp
9.224AspAla: 9.224 ± 0.13
0.441AspCys: 0.441 ± 0.024
3.937AspAsp: 3.937 ± 0.079
3.275AspGlu: 3.275 ± 0.074
2.326AspPhe: 2.326 ± 0.053
5.645AspGly: 5.645 ± 0.11
1.439AspHis: 1.439 ± 0.042
2.684AspIle: 2.684 ± 0.056
1.842AspLys: 1.842 ± 0.053
5.845AspLeu: 5.845 ± 0.088
1.375AspMet: 1.375 ± 0.042
1.375AspAsn: 1.375 ± 0.049
3.463AspPro: 3.463 ± 0.072
1.802AspGln: 1.802 ± 0.041
4.117AspArg: 4.117 ± 0.072
2.566AspSer: 2.566 ± 0.071
3.242AspThr: 3.242 ± 0.067
4.651AspVal: 4.651 ± 0.083
1.068AspTrp: 1.068 ± 0.032
1.644AspTyr: 1.644 ± 0.042
0.0AspXaa: 0.0 ± 0.0
Glu
6.611GluAla: 6.611 ± 0.121
0.365GluCys: 0.365 ± 0.02
2.673GluAsp: 2.673 ± 0.081
2.254GluGlu: 2.254 ± 0.071
1.404GluPhe: 1.404 ± 0.045
3.751GluGly: 3.751 ± 0.073
1.858GluHis: 1.858 ± 0.055
2.256GluIle: 2.256 ± 0.063
1.612GluLys: 1.612 ± 0.055
5.53GluLeu: 5.53 ± 0.111
1.053GluMet: 1.053 ± 0.04
1.311GluAsn: 1.311 ± 0.042
2.306GluPro: 2.306 ± 0.062
2.581GluGln: 2.581 ± 0.064
5.369GluArg: 5.369 ± 0.105
2.405GluSer: 2.405 ± 0.058
2.618GluThr: 2.618 ± 0.06
3.507GluVal: 3.507 ± 0.082
0.583GluTrp: 0.583 ± 0.029
1.07GluTyr: 1.07 ± 0.038
0.0GluXaa: 0.0 ± 0.0
Phe
4.307PheAla: 4.307 ± 0.086
0.338PheCys: 0.338 ± 0.02
2.736PheAsp: 2.736 ± 0.059
1.904PheGlu: 1.904 ± 0.049
1.251PhePhe: 1.251 ± 0.04
3.462PheGly: 3.462 ± 0.066
0.904PheHis: 0.904 ± 0.031
1.275PheIle: 1.275 ± 0.038
0.9PheLys: 0.9 ± 0.039
3.171PheLeu: 3.171 ± 0.069
0.758PheMet: 0.758 ± 0.028
1.008PheAsn: 1.008 ± 0.04
1.419PhePro: 1.419 ± 0.046
1.021PheGln: 1.021 ± 0.039
2.241PheArg: 2.241 ± 0.053
1.935PheSer: 1.935 ± 0.049
1.766PheThr: 1.766 ± 0.043
2.737PheVal: 2.737 ± 0.055
0.493PheTrp: 0.493 ± 0.025
0.906PheTyr: 0.906 ± 0.033
0.0PheXaa: 0.0 ± 0.0
Gly
8.764GlyAla: 8.764 ± 0.129
0.842GlyCys: 0.842 ± 0.034
4.873GlyAsp: 4.873 ± 0.094
4.376GlyGlu: 4.376 ± 0.093
3.357GlyPhe: 3.357 ± 0.063
6.794GlyGly: 6.794 ± 0.156
2.363GlyHis: 2.363 ± 0.055
3.95GlyIle: 3.95 ± 0.071
3.17GlyLys: 3.17 ± 0.071
8.512GlyLeu: 8.512 ± 0.119
2.438GlyMet: 2.438 ± 0.052
2.182GlyAsn: 2.182 ± 0.084
2.998GlyPro: 2.998 ± 0.067
2.907GlyGln: 2.907 ± 0.066
5.71GlyArg: 5.71 ± 0.1
4.7GlySer: 4.7 ± 0.143
4.447GlyThr: 4.447 ± 0.112
6.56GlyVal: 6.56 ± 0.092
1.53GlyTrp: 1.53 ± 0.045
2.464GlyTyr: 2.464 ± 0.059
0.0GlyXaa: 0.0 ± 0.0
His
3.851HisAla: 3.851 ± 0.078
0.268HisCys: 0.268 ± 0.019
1.699HisAsp: 1.699 ± 0.047
1.358HisGlu: 1.358 ± 0.044
1.061HisPhe: 1.061 ± 0.036
2.747HisGly: 2.747 ± 0.058
0.758HisHis: 0.758 ± 0.031
1.017HisIle: 1.017 ± 0.032
0.606HisLys: 0.606 ± 0.026
2.69HisLeu: 2.69 ± 0.059
0.635HisMet: 0.635 ± 0.027
0.557HisAsn: 0.557 ± 0.027
1.705HisPro: 1.705 ± 0.043
0.753HisGln: 0.753 ± 0.028
1.888HisArg: 1.888 ± 0.054
1.11HisSer: 1.11 ± 0.036
1.194HisThr: 1.194 ± 0.039
2.036HisVal: 2.036 ± 0.051
0.522HisTrp: 0.522 ± 0.024
0.77HisTyr: 0.77 ± 0.031
0.0HisXaa: 0.0 ± 0.0
Ile
6.045IleAla: 6.045 ± 0.077
0.355IleCys: 0.355 ± 0.02
3.55IleAsp: 3.55 ± 0.068
3.044IleGlu: 3.044 ± 0.068
1.25IlePhe: 1.25 ± 0.04
4.572IleGly: 4.572 ± 0.084
0.991IleHis: 0.991 ± 0.034
1.446IleIle: 1.446 ± 0.051
1.198IleLys: 1.198 ± 0.044
3.292IleLeu: 3.292 ± 0.072
0.714IleMet: 0.714 ± 0.032
1.178IleAsn: 1.178 ± 0.036
1.923IlePro: 1.923 ± 0.05
1.238IleGln: 1.238 ± 0.04
2.653IleArg: 2.653 ± 0.058
2.082IleSer: 2.082 ± 0.053
2.155IleThr: 2.155 ± 0.053
3.476IleVal: 3.476 ± 0.068
0.478IleTrp: 0.478 ± 0.028
0.959IleTyr: 0.959 ± 0.036
0.0IleXaa: 0.0 ± 0.0
Lys
3.562LysAla: 3.562 ± 0.082
0.149LysCys: 0.149 ± 0.015
1.646LysAsp: 1.646 ± 0.058
1.095LysGlu: 1.095 ± 0.046
0.769LysPhe: 0.769 ± 0.032
2.095LysGly: 2.095 ± 0.057
0.886LysHis: 0.886 ± 0.034
1.217LysIle: 1.217 ± 0.042
1.092LysLys: 1.092 ± 0.048
3.378LysLeu: 3.378 ± 0.068
0.629LysMet: 0.629 ± 0.027
0.842LysAsn: 0.842 ± 0.037
2.005LysPro: 2.005 ± 0.056
1.404LysGln: 1.404 ± 0.053
2.445LysArg: 2.445 ± 0.061
1.544LysSer: 1.544 ± 0.052
1.701LysThr: 1.701 ± 0.05
2.328LysVal: 2.328 ± 0.059
0.302LysTrp: 0.302 ± 0.018
0.617LysTyr: 0.617 ± 0.025
0.0LysXaa: 0.0 ± 0.0
Leu
13.497LeuAla: 13.497 ± 0.172
0.971LeuCys: 0.971 ± 0.037
7.378LeuAsp: 7.378 ± 0.112
5.145LeuGlu: 5.145 ± 0.119
3.598LeuPhe: 3.598 ± 0.073
8.703LeuGly: 8.703 ± 0.102
2.894LeuHis: 2.894 ± 0.059
4.535LeuIle: 4.535 ± 0.078
3.41LeuLys: 3.41 ± 0.079
11.552LeuLeu: 11.552 ± 0.176
2.303LeuMet: 2.303 ± 0.06
2.438LeuAsn: 2.438 ± 0.061
6.136LeuPro: 6.136 ± 0.096
4.007LeuGln: 4.007 ± 0.078
8.855LeuArg: 8.855 ± 0.151
6.064LeuSer: 6.064 ± 0.084
5.391LeuThr: 5.391 ± 0.092
7.137LeuVal: 7.137 ± 0.108
1.41LeuTrp: 1.41 ± 0.051
2.29LeuTyr: 2.29 ± 0.051
0.0LeuXaa: 0.0 ± 0.0
Met
2.794MetAla: 2.794 ± 0.063
0.154MetCys: 0.154 ± 0.012
1.248MetAsp: 1.248 ± 0.037
0.891MetGlu: 0.891 ± 0.037
0.727MetPhe: 0.727 ± 0.03
1.545MetGly: 1.545 ± 0.038
0.755MetHis: 0.755 ± 0.032
1.015MetIle: 1.015 ± 0.033
0.897MetLys: 0.897 ± 0.038
2.852MetLeu: 2.852 ± 0.059
0.51MetMet: 0.51 ± 0.024
0.857MetAsn: 0.857 ± 0.031
1.495MetPro: 1.495 ± 0.042
1.254MetGln: 1.254 ± 0.035
2.049MetArg: 2.049 ± 0.049
1.555MetSer: 1.555 ± 0.051
1.485MetThr: 1.485 ± 0.038
1.58MetVal: 1.58 ± 0.047
0.233MetTrp: 0.233 ± 0.018
0.455MetTyr: 0.455 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
3.214AsnAla: 3.214 ± 0.074
0.223AsnCys: 0.223 ± 0.018
1.506AsnAsp: 1.506 ± 0.042
1.144AsnGlu: 1.144 ± 0.037
0.894AsnPhe: 0.894 ± 0.031
2.41AsnGly: 2.41 ± 0.069
0.575AsnHis: 0.575 ± 0.028
1.091AsnIle: 1.091 ± 0.041
0.705AsnLys: 0.705 ± 0.036
2.691AsnLeu: 2.691 ± 0.067
0.528AsnMet: 0.528 ± 0.026
0.769AsnAsn: 0.769 ± 0.038
1.577AsnPro: 1.577 ± 0.049
0.77AsnGln: 0.77 ± 0.032
1.646AsnArg: 1.646 ± 0.048
1.06AsnSer: 1.06 ± 0.05
1.305AsnThr: 1.305 ± 0.054
1.953AsnVal: 1.953 ± 0.069
0.399AsnTrp: 0.399 ± 0.02
0.722AsnTyr: 0.722 ± 0.033
0.0AsnXaa: 0.0 ± 0.0
Pro
5.862ProAla: 5.862 ± 0.107
0.369ProCys: 0.369 ± 0.02
3.69ProAsp: 3.69 ± 0.062
3.074ProGlu: 3.074 ± 0.065
1.708ProPhe: 1.708 ± 0.043
4.223ProGly: 4.223 ± 0.071
1.303ProHis: 1.303 ± 0.04
1.915ProIle: 1.915 ± 0.049
1.528ProLys: 1.528 ± 0.05
5.131ProLeu: 5.131 ± 0.08
1.324ProMet: 1.324 ± 0.042
1.324ProAsn: 1.324 ± 0.046
2.516ProPro: 2.516 ± 0.082
2.119ProGln: 2.119 ± 0.058
3.253ProArg: 3.253 ± 0.072
2.926ProSer: 2.926 ± 0.061
2.479ProThr: 2.479 ± 0.055
3.866ProVal: 3.866 ± 0.07
0.89ProTrp: 0.89 ± 0.037
1.253ProTyr: 1.253 ± 0.039
0.0ProXaa: 0.0 ± 0.0
Gln
5.196GlnAla: 5.196 ± 0.091
0.31GlnCys: 0.31 ± 0.023
1.65GlnAsp: 1.65 ± 0.049
1.29GlnGlu: 1.29 ± 0.045
1.133GlnPhe: 1.133 ± 0.037
2.754GlnGly: 2.754 ± 0.071
1.095GlnHis: 1.095 ± 0.038
1.584GlnIle: 1.584 ± 0.046
1.002GlnLys: 1.002 ± 0.035
3.982GlnLeu: 3.982 ± 0.079
0.869GlnMet: 0.869 ± 0.028
0.804GlnAsn: 0.804 ± 0.036
2.166GlnPro: 2.166 ± 0.044
1.811GlnGln: 1.811 ± 0.059
3.834GlnArg: 3.834 ± 0.074
1.826GlnSer: 1.826 ± 0.053
1.892GlnThr: 1.892 ± 0.047
2.832GlnVal: 2.832 ± 0.056
0.597GlnTrp: 0.597 ± 0.026
0.869GlnTyr: 0.869 ± 0.034
0.0GlnXaa: 0.0 ± 0.0
Arg
8.401ArgAla: 8.401 ± 0.122
0.612ArgCys: 0.612 ± 0.027
4.569ArgAsp: 4.569 ± 0.079
4.823ArgGlu: 4.823 ± 0.115
3.027ArgPhe: 3.027 ± 0.057
5.107ArgGly: 5.107 ± 0.088
2.24ArgHis: 2.24 ± 0.061
3.885ArgIle: 3.885 ± 0.078
2.377ArgLys: 2.377 ± 0.051
8.381ArgLeu: 8.381 ± 0.148
2.211ArgMet: 2.211 ± 0.048
1.959ArgAsn: 1.959 ± 0.045
3.253ArgPro: 3.253 ± 0.073
2.724ArgGln: 2.724 ± 0.057
6.204ArgArg: 6.204 ± 0.127
3.676ArgSer: 3.676 ± 0.074
3.471ArgThr: 3.471 ± 0.068
5.549ArgVal: 5.549 ± 0.101
1.361ArgTrp: 1.361 ± 0.047
2.256ArgTyr: 2.256 ± 0.056
0.0ArgXaa: 0.0 ± 0.0
Ser
6.206SerAla: 6.206 ± 0.127
0.416SerCys: 0.416 ± 0.024
3.247SerAsp: 3.247 ± 0.071
2.543SerGlu: 2.543 ± 0.058
1.866SerPhe: 1.866 ± 0.048
5.352SerGly: 5.352 ± 0.117
1.214SerHis: 1.214 ± 0.032
2.34SerIle: 2.34 ± 0.055
1.481SerLys: 1.481 ± 0.044
5.374SerLeu: 5.374 ± 0.086
1.471SerMet: 1.471 ± 0.043
1.425SerAsn: 1.425 ± 0.05
2.494SerPro: 2.494 ± 0.064
1.618SerGln: 1.618 ± 0.047
3.426SerArg: 3.426 ± 0.067
2.932SerSer: 2.932 ± 0.086
2.833SerThr: 2.833 ± 0.08
3.892SerVal: 3.892 ± 0.096
0.745SerTrp: 0.745 ± 0.031
1.329SerTyr: 1.329 ± 0.048
0.0SerXaa: 0.0 ± 0.0
Thr
5.603ThrAla: 5.603 ± 0.1
0.454ThrCys: 0.454 ± 0.026
2.858ThrAsp: 2.858 ± 0.067
2.166ThrGlu: 2.166 ± 0.056
1.729ThrPhe: 1.729 ± 0.043
4.375ThrGly: 4.375 ± 0.093
1.453ThrHis: 1.453 ± 0.043
2.033ThrIle: 2.033 ± 0.059
1.124ThrLys: 1.124 ± 0.041
6.633ThrLeu: 6.633 ± 0.103
1.055ThrMet: 1.055 ± 0.034
1.078ThrAsn: 1.078 ± 0.037
3.509ThrPro: 3.509 ± 0.066
1.863ThrGln: 1.863 ± 0.052
3.667ThrArg: 3.667 ± 0.065
2.505ThrSer: 2.505 ± 0.09
2.578ThrThr: 2.578 ± 0.084
4.14ThrVal: 4.14 ± 0.081
0.765ThrTrp: 0.765 ± 0.031
1.23ThrTyr: 1.23 ± 0.043
0.0ThrXaa: 0.0 ± 0.0
Val
8.612ValAla: 8.612 ± 0.105
0.754ValCys: 0.754 ± 0.03
4.76ValAsp: 4.76 ± 0.071
4.09ValGlu: 4.09 ± 0.09
2.56ValPhe: 2.56 ± 0.051
5.561ValGly: 5.561 ± 0.106
2.02ValHis: 2.02 ± 0.052
3.383ValIle: 3.383 ± 0.074
1.975ValLys: 1.975 ± 0.062
8.24ValLeu: 8.24 ± 0.114
1.774ValMet: 1.774 ± 0.052
1.975ValAsn: 1.975 ± 0.069
3.65ValPro: 3.65 ± 0.068
2.675ValGln: 2.675 ± 0.053
5.45ValArg: 5.45 ± 0.1
4.015ValSer: 4.015 ± 0.084
3.98ValThr: 3.98 ± 0.081
5.765ValVal: 5.765 ± 0.096
0.969ValTrp: 0.969 ± 0.034
1.749ValTyr: 1.749 ± 0.048
0.0ValXaa: 0.0 ± 0.0
Trp
1.227TrpAla: 1.227 ± 0.042
0.154TrpCys: 0.154 ± 0.013
0.683TrpAsp: 0.683 ± 0.029
0.459TrpGlu: 0.459 ± 0.024
0.601TrpPhe: 0.601 ± 0.026
0.934TrpGly: 0.934 ± 0.037
0.433TrpHis: 0.433 ± 0.023
0.778TrpIle: 0.778 ± 0.035
0.541TrpLys: 0.541 ± 0.026
2.182TrpLeu: 2.182 ± 0.05
0.494TrpMet: 0.494 ± 0.024
0.557TrpAsn: 0.557 ± 0.027
0.805TrpPro: 0.805 ± 0.035
0.724TrpGln: 0.724 ± 0.035
1.291TrpArg: 1.291 ± 0.039
0.963TrpSer: 0.963 ± 0.033
0.805TrpThr: 0.805 ± 0.034
0.959TrpVal: 0.959 ± 0.037
0.315TrpTrp: 0.315 ± 0.021
0.354TrpTyr: 0.354 ± 0.022
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.035TyrAla: 3.035 ± 0.067
0.221TyrCys: 0.221 ± 0.017
1.553TyrAsp: 1.553 ± 0.051
1.096TyrGlu: 1.096 ± 0.038
0.943TyrPhe: 0.943 ± 0.034
2.263TyrGly: 2.263 ± 0.052
0.592TyrHis: 0.592 ± 0.023
0.847TyrIle: 0.847 ± 0.032
0.607TyrLys: 0.607 ± 0.03
2.527TyrLeu: 2.527 ± 0.054
0.483TyrMet: 0.483 ± 0.022
0.625TyrAsn: 0.625 ± 0.031
1.206TyrPro: 1.206 ± 0.038
0.858TyrGln: 0.858 ± 0.036
2.173TyrArg: 2.173 ± 0.055
1.205TyrSer: 1.205 ± 0.04
1.332TyrThr: 1.332 ± 0.05
1.828TyrVal: 1.828 ± 0.053
0.401TyrTrp: 0.401 ± 0.02
0.73TyrTyr: 0.73 ± 0.032
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2676 proteins (872925 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski