Amino acid dipepetide frequency for Beihai sobemo-like virus 27

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.147AlaAla: 8.147 ± 1.075
1.018AlaCys: 1.018 ± 0.944
2.037AlaAsp: 2.037 ± 1.888
7.128AlaGlu: 7.128 ± 1.751
7.128AlaPhe: 7.128 ± 1.751
4.073AlaGly: 4.073 ± 1.082
2.037AlaHis: 2.037 ± 0.269
3.055AlaIle: 3.055 ± 2.026
7.128AlaLys: 7.128 ± 1.751
14.257AlaLeu: 14.257 ± 0.262
0.0AlaMet: 0.0 ± 0.0
4.073AlaAsn: 4.073 ± 0.538
5.092AlaPro: 5.092 ± 1.482
3.055AlaGln: 3.055 ± 0.407
7.128AlaArg: 7.128 ± 3.108
2.037AlaSer: 2.037 ± 0.269
9.165AlaThr: 9.165 ± 2.839
7.128AlaVal: 7.128 ± 1.488
3.055AlaTrp: 3.055 ± 1.213
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.018CysGlu: 1.018 ± 0.675
1.018CysPhe: 1.018 ± 0.944
1.018CysGly: 1.018 ± 0.944
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
5.092CysLeu: 5.092 ± 1.757
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.018CysGln: 1.018 ± 0.944
0.0CysArg: 0.0 ± 0.0
2.037CysSer: 2.037 ± 0.269
1.018CysThr: 1.018 ± 0.944
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.092AspAla: 5.092 ± 0.138
0.0AspCys: 0.0 ± 0.0
2.037AspAsp: 2.037 ± 0.269
1.018AspGlu: 1.018 ± 0.944
4.073AspPhe: 4.073 ± 1.082
3.055AspGly: 3.055 ± 1.213
0.0AspHis: 0.0 ± 0.0
3.055AspIle: 3.055 ± 2.026
1.018AspLys: 1.018 ± 0.944
3.055AspLeu: 3.055 ± 0.407
2.037AspMet: 2.037 ± 0.269
1.018AspAsn: 1.018 ± 0.675
2.037AspPro: 2.037 ± 0.269
0.0AspGln: 0.0 ± 0.0
2.037AspArg: 2.037 ± 0.269
6.11AspSer: 6.11 ± 0.813
2.037AspThr: 2.037 ± 0.269
2.037AspVal: 2.037 ± 1.351
3.055AspTrp: 3.055 ± 2.832
1.018AspTyr: 1.018 ± 0.675
0.0AspXaa: 0.0 ± 0.0
Glu
7.128GluAla: 7.128 ± 1.751
1.018GluCys: 1.018 ± 0.675
3.055GluAsp: 3.055 ± 2.026
2.037GluGlu: 2.037 ± 0.269
1.018GluPhe: 1.018 ± 0.675
2.037GluGly: 2.037 ± 1.888
3.055GluHis: 3.055 ± 1.213
1.018GluIle: 1.018 ± 0.944
1.018GluLys: 1.018 ± 0.675
11.202GluLeu: 11.202 ± 0.669
2.037GluMet: 2.037 ± 1.351
0.0GluAsn: 0.0 ± 0.0
5.092GluPro: 5.092 ± 1.482
4.073GluGln: 4.073 ± 3.777
5.092GluArg: 5.092 ± 1.482
5.092GluSer: 5.092 ± 1.757
3.055GluThr: 3.055 ± 0.407
1.018GluVal: 1.018 ± 0.675
1.018GluTrp: 1.018 ± 0.944
4.073GluTyr: 4.073 ± 0.538
0.0GluXaa: 0.0 ± 0.0
Phe
4.073PheAla: 4.073 ± 2.157
1.018PheCys: 1.018 ± 0.675
1.018PheAsp: 1.018 ± 0.675
3.055PheGlu: 3.055 ± 1.213
0.0PhePhe: 0.0 ± 0.0
3.055PheGly: 3.055 ± 2.026
1.018PheHis: 1.018 ± 0.944
1.018PheIle: 1.018 ± 0.944
2.037PheLys: 2.037 ± 1.888
2.037PheLeu: 2.037 ± 1.351
4.073PheMet: 4.073 ± 0.538
1.018PheAsn: 1.018 ± 0.944
1.018PhePro: 1.018 ± 0.675
2.037PheGln: 2.037 ± 0.269
0.0PheArg: 0.0 ± 0.0
3.055PheSer: 3.055 ± 2.026
1.018PheThr: 1.018 ± 0.675
4.073PheVal: 4.073 ± 2.701
1.018PheTrp: 1.018 ± 0.944
1.018PheTyr: 1.018 ± 0.944
0.0PheXaa: 0.0 ± 0.0
Gly
7.128GlyAla: 7.128 ± 3.108
5.092GlyCys: 5.092 ± 0.138
7.128GlyAsp: 7.128 ± 1.488
4.073GlyGlu: 4.073 ± 0.538
3.055GlyPhe: 3.055 ± 0.407
5.092GlyGly: 5.092 ± 1.757
0.0GlyHis: 0.0 ± 0.0
3.055GlyIle: 3.055 ± 0.407
4.073GlyLys: 4.073 ± 2.701
5.092GlyLeu: 5.092 ± 1.757
0.0GlyMet: 0.0 ± 0.0
2.037GlyAsn: 2.037 ± 1.351
3.055GlyPro: 3.055 ± 0.407
0.0GlyGln: 0.0 ± 0.0
1.018GlyArg: 1.018 ± 0.944
3.055GlySer: 3.055 ± 2.026
3.055GlyThr: 3.055 ± 0.407
6.11GlyVal: 6.11 ± 2.433
2.037GlyTrp: 2.037 ± 1.888
7.128GlyTyr: 7.128 ± 0.131
0.0GlyXaa: 0.0 ± 0.0
His
2.037HisAla: 2.037 ± 0.269
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.018HisPhe: 1.018 ± 0.944
3.055HisGly: 3.055 ± 0.407
2.037HisHis: 2.037 ± 1.351
2.037HisIle: 2.037 ± 1.888
2.037HisLys: 2.037 ± 0.269
5.092HisLeu: 5.092 ± 0.138
2.037HisMet: 2.037 ± 1.351
0.0HisAsn: 0.0 ± 0.0
1.018HisPro: 1.018 ± 0.675
0.0HisGln: 0.0 ± 0.0
3.055HisArg: 3.055 ± 0.407
2.037HisSer: 2.037 ± 0.269
2.037HisThr: 2.037 ± 1.351
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
3.055HisTyr: 3.055 ± 2.832
0.0HisXaa: 0.0 ± 0.0
Ile
1.018IleAla: 1.018 ± 0.675
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
1.018IleGlu: 1.018 ± 0.944
0.0IlePhe: 0.0 ± 0.0
3.055IleGly: 3.055 ± 0.407
2.037IleHis: 2.037 ± 1.888
2.037IleIle: 2.037 ± 1.351
4.073IleLys: 4.073 ± 2.157
5.092IleLeu: 5.092 ± 1.482
1.018IleMet: 1.018 ± 0.675
0.0IleAsn: 0.0 ± 0.0
2.037IlePro: 2.037 ± 1.351
0.0IleGln: 0.0 ± 0.0
2.037IleArg: 2.037 ± 1.351
4.073IleSer: 4.073 ± 2.157
2.037IleThr: 2.037 ± 0.269
3.055IleVal: 3.055 ± 1.213
0.0IleTrp: 0.0 ± 0.0
3.055IleTyr: 3.055 ± 2.026
0.0IleXaa: 0.0 ± 0.0
Lys
7.128LysAla: 7.128 ± 0.131
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
2.037LysGlu: 2.037 ± 1.888
2.037LysPhe: 2.037 ± 0.269
4.073LysGly: 4.073 ± 0.538
1.018LysHis: 1.018 ± 0.944
1.018LysIle: 1.018 ± 0.944
6.11LysLys: 6.11 ± 0.813
4.073LysLeu: 4.073 ± 2.157
0.0LysMet: 0.0 ± 0.0
4.073LysAsn: 4.073 ± 1.082
3.055LysPro: 3.055 ± 0.407
2.037LysGln: 2.037 ± 1.351
4.073LysArg: 4.073 ± 0.538
9.165LysSer: 9.165 ± 1.22
1.018LysThr: 1.018 ± 0.675
4.073LysVal: 4.073 ± 0.538
2.037LysTrp: 2.037 ± 0.269
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
9.165LeuAla: 9.165 ± 0.4
1.018LeuCys: 1.018 ± 0.944
3.055LeuAsp: 3.055 ± 1.213
8.147LeuGlu: 8.147 ± 4.314
3.055LeuPhe: 3.055 ± 2.026
7.128LeuGly: 7.128 ± 4.727
2.037LeuHis: 2.037 ± 0.269
3.055LeuIle: 3.055 ± 1.213
4.073LeuLys: 4.073 ± 1.082
10.183LeuLeu: 10.183 ± 4.583
1.018LeuMet: 1.018 ± 0.944
4.073LeuAsn: 4.073 ± 0.538
8.147LeuPro: 8.147 ± 1.075
2.037LeuGln: 2.037 ± 1.888
8.147LeuArg: 8.147 ± 0.544
7.128LeuSer: 7.128 ± 3.108
4.073LeuThr: 4.073 ± 1.082
3.055LeuVal: 3.055 ± 0.407
1.018LeuTrp: 1.018 ± 0.944
5.092LeuTyr: 5.092 ± 1.482
0.0LeuXaa: 0.0 ± 0.0
Met
2.037MetAla: 2.037 ± 1.351
1.018MetCys: 1.018 ± 0.675
2.037MetAsp: 2.037 ± 1.351
2.037MetGlu: 2.037 ± 1.351
1.018MetPhe: 1.018 ± 0.675
2.037MetGly: 2.037 ± 0.269
0.0MetHis: 0.0 ± 0.0
1.018MetIle: 1.018 ± 0.675
2.037MetLys: 2.037 ± 1.888
1.018MetLeu: 1.018 ± 0.675
1.018MetMet: 1.018 ± 0.944
1.018MetAsn: 1.018 ± 0.675
2.037MetPro: 2.037 ± 1.351
0.0MetGln: 0.0 ± 0.0
3.055MetArg: 3.055 ± 0.407
2.037MetSer: 2.037 ± 0.269
4.073MetThr: 4.073 ± 1.082
3.055MetVal: 3.055 ± 0.407
0.0MetTrp: 0.0 ± 0.0
2.037MetTyr: 2.037 ± 1.888
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
1.018AsnCys: 1.018 ± 0.944
3.055AsnAsp: 3.055 ± 0.407
4.073AsnGlu: 4.073 ± 1.082
1.018AsnPhe: 1.018 ± 0.944
6.11AsnGly: 6.11 ± 2.433
1.018AsnHis: 1.018 ± 0.675
1.018AsnIle: 1.018 ± 0.675
0.0AsnLys: 0.0 ± 0.0
0.0AsnLeu: 0.0 ± 0.0
1.018AsnMet: 1.018 ± 0.675
0.0AsnAsn: 0.0 ± 0.0
3.055AsnPro: 3.055 ± 0.407
0.0AsnGln: 0.0 ± 0.0
1.018AsnArg: 1.018 ± 0.675
3.055AsnSer: 3.055 ± 1.213
2.037AsnThr: 2.037 ± 1.888
3.055AsnVal: 3.055 ± 0.407
1.018AsnTrp: 1.018 ± 0.944
1.018AsnTyr: 1.018 ± 0.944
0.0AsnXaa: 0.0 ± 0.0
Pro
4.073ProAla: 4.073 ± 0.538
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
6.11ProGlu: 6.11 ± 2.426
1.018ProPhe: 1.018 ± 0.675
4.073ProGly: 4.073 ± 0.538
1.018ProHis: 1.018 ± 0.944
0.0ProIle: 0.0 ± 0.0
1.018ProLys: 1.018 ± 0.675
2.037ProLeu: 2.037 ± 1.888
4.073ProMet: 4.073 ± 0.272
2.037ProAsn: 2.037 ± 0.269
6.11ProPro: 6.11 ± 2.433
1.018ProGln: 1.018 ± 0.675
0.0ProArg: 0.0 ± 0.0
9.165ProSer: 9.165 ± 1.22
6.11ProThr: 6.11 ± 0.813
3.055ProVal: 3.055 ± 1.213
0.0ProTrp: 0.0 ± 0.0
1.018ProTyr: 1.018 ± 0.675
0.0ProXaa: 0.0 ± 0.0
Gln
5.092GlnAla: 5.092 ± 1.482
0.0GlnCys: 0.0 ± 0.0
1.018GlnAsp: 1.018 ± 0.944
0.0GlnGlu: 0.0 ± 0.0
1.018GlnPhe: 1.018 ± 0.944
2.037GlnGly: 2.037 ± 0.269
1.018GlnHis: 1.018 ± 0.675
1.018GlnIle: 1.018 ± 0.944
2.037GlnLys: 2.037 ± 1.888
2.037GlnLeu: 2.037 ± 1.351
1.018GlnMet: 1.018 ± 0.675
2.037GlnAsn: 2.037 ± 0.269
0.0GlnPro: 0.0 ± 0.0
2.037GlnGln: 2.037 ± 1.888
1.018GlnArg: 1.018 ± 0.675
4.073GlnSer: 4.073 ± 0.538
2.037GlnThr: 2.037 ± 0.269
1.018GlnVal: 1.018 ± 0.675
0.0GlnTrp: 0.0 ± 0.0
1.018GlnTyr: 1.018 ± 0.675
0.0GlnXaa: 0.0 ± 0.0
Arg
7.128ArgAla: 7.128 ± 3.108
0.0ArgCys: 0.0 ± 0.0
2.037ArgAsp: 2.037 ± 0.269
4.073ArgGlu: 4.073 ± 0.538
1.018ArgPhe: 1.018 ± 0.675
3.055ArgGly: 3.055 ± 2.026
2.037ArgHis: 2.037 ± 0.269
2.037ArgIle: 2.037 ± 0.269
4.073ArgLys: 4.073 ± 2.701
9.165ArgLeu: 9.165 ± 0.4
3.055ArgMet: 3.055 ± 0.407
0.0ArgAsn: 0.0 ± 0.0
3.055ArgPro: 3.055 ± 0.407
1.018ArgGln: 1.018 ± 0.675
2.037ArgArg: 2.037 ± 0.269
3.055ArgSer: 3.055 ± 0.407
6.11ArgThr: 6.11 ± 2.426
2.037ArgVal: 2.037 ± 1.888
3.055ArgTrp: 3.055 ± 2.832
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.055SerAla: 3.055 ± 2.026
0.0SerCys: 0.0 ± 0.0
1.018SerAsp: 1.018 ± 0.944
11.202SerGlu: 11.202 ± 4.19
3.055SerPhe: 3.055 ± 0.407
9.165SerGly: 9.165 ± 2.839
3.055SerHis: 3.055 ± 0.407
1.018SerIle: 1.018 ± 0.944
7.128SerLys: 7.128 ± 0.131
2.037SerLeu: 2.037 ± 0.269
4.073SerMet: 4.073 ± 2.701
6.11SerAsn: 6.11 ± 0.813
3.055SerPro: 3.055 ± 2.832
4.073SerGln: 4.073 ± 2.701
8.147SerArg: 8.147 ± 0.544
7.128SerSer: 7.128 ± 3.108
3.055SerThr: 3.055 ± 0.407
1.018SerVal: 1.018 ± 0.944
0.0SerTrp: 0.0 ± 0.0
2.037SerTyr: 2.037 ± 1.888
0.0SerXaa: 0.0 ± 0.0
Thr
6.11ThrAla: 6.11 ± 2.426
0.0ThrCys: 0.0 ± 0.0
5.092ThrAsp: 5.092 ± 0.138
2.037ThrGlu: 2.037 ± 1.351
1.018ThrPhe: 1.018 ± 0.944
2.037ThrGly: 2.037 ± 1.351
2.037ThrHis: 2.037 ± 1.351
7.128ThrIle: 7.128 ± 1.751
3.055ThrLys: 3.055 ± 2.026
6.11ThrLeu: 6.11 ± 2.426
1.018ThrMet: 1.018 ± 0.675
2.037ThrAsn: 2.037 ± 0.269
2.037ThrPro: 2.037 ± 0.269
1.018ThrGln: 1.018 ± 0.675
2.037ThrArg: 2.037 ± 0.269
4.073ThrSer: 4.073 ± 1.082
4.073ThrThr: 4.073 ± 2.701
7.128ThrVal: 7.128 ± 1.488
0.0ThrTrp: 0.0 ± 0.0
2.037ThrTyr: 2.037 ± 1.351
0.0ThrXaa: 0.0 ± 0.0
Val
11.202ValAla: 11.202 ± 2.57
0.0ValCys: 0.0 ± 0.0
3.055ValAsp: 3.055 ± 0.407
3.055ValGlu: 3.055 ± 0.407
3.055ValPhe: 3.055 ± 0.407
4.073ValGly: 4.073 ± 2.701
2.037ValHis: 2.037 ± 1.351
1.018ValIle: 1.018 ± 0.675
4.073ValLys: 4.073 ± 0.538
3.055ValLeu: 3.055 ± 0.407
1.018ValMet: 1.018 ± 0.675
0.0ValAsn: 0.0 ± 0.0
2.037ValPro: 2.037 ± 0.269
3.055ValGln: 3.055 ± 2.832
2.037ValArg: 2.037 ± 0.269
2.037ValSer: 2.037 ± 0.269
3.055ValThr: 3.055 ± 0.407
5.092ValVal: 5.092 ± 3.377
3.055ValTrp: 3.055 ± 0.407
1.018ValTyr: 1.018 ± 0.944
0.0ValXaa: 0.0 ± 0.0
Trp
4.073TrpAla: 4.073 ± 2.157
1.018TrpCys: 1.018 ± 0.944
2.037TrpAsp: 2.037 ± 1.888
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.018TrpGly: 1.018 ± 0.944
1.018TrpHis: 1.018 ± 0.944
0.0TrpIle: 0.0 ± 0.0
2.037TrpLys: 2.037 ± 1.888
3.055TrpLeu: 3.055 ± 0.407
1.018TrpMet: 1.018 ± 0.944
1.018TrpAsn: 1.018 ± 0.944
0.0TrpPro: 0.0 ± 0.0
1.018TrpGln: 1.018 ± 0.944
4.073TrpArg: 4.073 ± 2.157
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.055TyrAla: 3.055 ± 2.832
0.0TyrCys: 0.0 ± 0.0
6.11TyrAsp: 6.11 ± 0.813
1.018TyrGlu: 1.018 ± 0.944
2.037TyrPhe: 2.037 ± 0.269
2.037TyrGly: 2.037 ± 0.269
4.073TyrHis: 4.073 ± 1.082
2.037TyrIle: 2.037 ± 0.269
0.0TyrLys: 0.0 ± 0.0
1.018TyrLeu: 1.018 ± 0.944
2.037TyrMet: 2.037 ± 0.269
2.037TyrAsn: 2.037 ± 0.269
1.018TyrPro: 1.018 ± 0.944
2.037TyrGln: 2.037 ± 1.351
2.037TyrArg: 2.037 ± 0.269
1.018TyrSer: 1.018 ± 0.675
1.018TyrThr: 1.018 ± 0.944
1.018TyrVal: 1.018 ± 0.944
1.018TyrTrp: 1.018 ± 0.944
1.018TyrTyr: 1.018 ± 0.944
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (983 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski