Amino acid dipepetide frequency for Desulfovibrio alaskensis (strain ATCC BAA 1058 / DSM 17464 / G20) (Desulfovibrio desulfuricans (strain G20))

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.286AlaAla: 15.286 ± 0.218	1.726AlaCys: 1.726 ± 0.039	6.008AlaAsp: 6.008 ± 0.078	6.955AlaGlu: 6.955 ± 0.092	3.675AlaPhe: 3.675 ± 0.063	10.542AlaGly: 10.542 ± 0.125	2.18AlaHis: 2.18 ± 0.046	3.977AlaIle: 3.977 ± 0.061	2.95AlaLys: 2.95 ± 0.072	11.808AlaLeu: 11.808 ± 0.135	3.226AlaMet: 3.226 ± 0.054	2.051AlaAsn: 2.051 ± 0.039	4.617AlaPro: 4.617 ± 0.075	4.0AlaGln: 4.0 ± 0.058	7.431AlaArg: 7.431 ± 0.103	5.176AlaSer: 5.176 ± 0.075	4.534AlaThr: 4.534 ± 0.076	9.366AlaVal: 9.366 ± 0.12	1.211AlaTrp: 1.211 ± 0.037	2.312AlaTyr: 2.312 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.507CysAla: 1.507 ± 0.04	0.316CysCys: 0.316 ± 0.02	0.66CysAsp: 0.66 ± 0.028	0.643CysGlu: 0.643 ± 0.025	0.48CysPhe: 0.48 ± 0.021	1.621CysGly: 1.621 ± 0.039	0.448CysHis: 0.448 ± 0.03	0.712CysIle: 0.712 ± 0.029	0.416CysLys: 0.416 ± 0.022	1.241CysLeu: 1.241 ± 0.035	0.389CysMet: 0.389 ± 0.018	0.405CysAsn: 0.405 ± 0.019	0.966CysPro: 0.966 ± 0.038	0.336CysGln: 0.336 ± 0.017	1.172CysArg: 1.172 ± 0.036	0.915CysSer: 0.915 ± 0.032	0.857CysThr: 0.857 ± 0.028	0.943CysVal: 0.943 ± 0.033	0.146CysTrp: 0.146 ± 0.013	0.344CysTyr: 0.344 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	5.811AspAla: 5.811 ± 0.073	0.666AspCys: 0.666 ± 0.025	2.87AspAsp: 2.87 ± 0.067	3.575AspGlu: 3.575 ± 0.07	2.27AspPhe: 2.27 ± 0.044	4.363AspGly: 4.363 ± 0.066	1.06AspHis: 1.06 ± 0.032	3.42AspIle: 3.42 ± 0.06	2.067AspLys: 2.067 ± 0.045	4.851AspLeu: 4.851 ± 0.076	1.828AspMet: 1.828 ± 0.042	1.649AspAsn: 1.649 ± 0.043	2.618AspPro: 2.618 ± 0.052	1.211AspGln: 1.211 ± 0.036	3.212AspArg: 3.212 ± 0.058	3.016AspSer: 3.016 ± 0.055	2.996AspThr: 2.996 ± 0.055	4.047AspVal: 4.047 ± 0.062	0.753AspTrp: 0.753 ± 0.029	1.494AspTyr: 1.494 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	6.528GluAla: 6.528 ± 0.09	0.648GluCys: 0.648 ± 0.025	3.053GluAsp: 3.053 ± 0.061	4.343GluGlu: 4.343 ± 0.074	2.031GluPhe: 2.031 ± 0.044	4.073GluGly: 4.073 ± 0.063	1.678GluHis: 1.678 ± 0.047	3.067GluIle: 3.067 ± 0.058	3.379GluLys: 3.379 ± 0.063	6.38GluLeu: 6.38 ± 0.087	1.769GluMet: 1.769 ± 0.036	2.193GluAsn: 2.193 ± 0.054	2.27GluPro: 2.27 ± 0.049	3.004GluGln: 3.004 ± 0.054	4.231GluArg: 4.231 ± 0.069	3.014GluSer: 3.014 ± 0.058	3.31GluThr: 3.31 ± 0.065	4.084GluVal: 4.084 ± 0.072	0.583GluTrp: 0.583 ± 0.025	1.679GluTyr: 1.679 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.728PheAla: 3.728 ± 0.069	0.662PheCys: 0.662 ± 0.023	2.194PheAsp: 2.194 ± 0.051	2.011PheGlu: 2.011 ± 0.049	1.806PhePhe: 1.806 ± 0.046	3.009PheGly: 3.009 ± 0.058	0.771PheHis: 0.771 ± 0.024	2.11PheIle: 2.11 ± 0.049	1.232PheLys: 1.232 ± 0.038	3.544PheLeu: 3.544 ± 0.065	1.222PheMet: 1.222 ± 0.035	1.134PheAsn: 1.134 ± 0.031	1.593PhePro: 1.593 ± 0.043	0.909PheGln: 0.909 ± 0.03	2.439PheArg: 2.439 ± 0.053	2.845PheSer: 2.845 ± 0.056	2.281PheThr: 2.281 ± 0.052	2.601PheVal: 2.601 ± 0.057	0.55PheTrp: 0.55 ± 0.022	1.121PheTyr: 1.121 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	7.485GlyAla: 7.485 ± 0.115	1.358GlyCys: 1.358 ± 0.043	3.847GlyAsp: 3.847 ± 0.075	4.281GlyGlu: 4.281 ± 0.065	3.192GlyPhe: 3.192 ± 0.059	6.459GlyGly: 6.459 ± 0.098	1.894GlyHis: 1.894 ± 0.045	4.85GlyIle: 4.85 ± 0.068	3.564GlyLys: 3.564 ± 0.065	8.189GlyLeu: 8.189 ± 0.101	2.805GlyMet: 2.805 ± 0.056	2.323GlyAsn: 2.323 ± 0.054	2.645GlyPro: 2.645 ± 0.052	2.642GlyGln: 2.642 ± 0.053	5.748GlyArg: 5.748 ± 0.088	4.445GlySer: 4.445 ± 0.069	4.865GlyThr: 4.865 ± 0.067	6.144GlyVal: 6.144 ± 0.093	1.111GlyTrp: 1.111 ± 0.034	2.484GlyTyr: 2.484 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	2.453HisAla: 2.453 ± 0.048	0.404HisCys: 0.404 ± 0.021	1.399HisAsp: 1.399 ± 0.037	1.374HisGlu: 1.374 ± 0.04	0.866HisPhe: 0.866 ± 0.03	2.03HisGly: 2.03 ± 0.044	0.582HisHis: 0.582 ± 0.024	1.257HisIle: 1.257 ± 0.039	0.833HisLys: 0.833 ± 0.025	2.111HisLeu: 2.111 ± 0.053	0.685HisMet: 0.685 ± 0.027	0.715HisAsn: 0.715 ± 0.027	1.418HisPro: 1.418 ± 0.042	0.611HisGln: 0.611 ± 0.025	1.448HisArg: 1.448 ± 0.038	1.306HisSer: 1.306 ± 0.034	1.423HisThr: 1.423 ± 0.039	1.566HisVal: 1.566 ± 0.038	0.315HisTrp: 0.315 ± 0.017	0.652HisTyr: 0.652 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.014IleAla: 5.014 ± 0.075	0.706IleCys: 0.706 ± 0.023	2.648IleAsp: 2.648 ± 0.053	2.816IleGlu: 2.816 ± 0.053	1.766IlePhe: 1.766 ± 0.04	3.493IleGly: 3.493 ± 0.064	1.044IleHis: 1.044 ± 0.032	2.773IleIle: 2.773 ± 0.064	1.78IleLys: 1.78 ± 0.05	4.506IleLeu: 4.506 ± 0.072	1.384IleMet: 1.384 ± 0.04	1.545IleAsn: 1.545 ± 0.044	2.595IlePro: 2.595 ± 0.052	1.376IleGln: 1.376 ± 0.035	3.527IleArg: 3.527 ± 0.065	3.08IleSer: 3.08 ± 0.054	2.934IleThr: 2.934 ± 0.056	3.509IleVal: 3.509 ± 0.067	0.454IleTrp: 0.454 ± 0.024	1.17IleTyr: 1.17 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.232LysAla: 4.232 ± 0.072	0.337LysCys: 0.337 ± 0.02	2.095LysAsp: 2.095 ± 0.05	2.643LysGlu: 2.643 ± 0.058	0.963LysPhe: 0.963 ± 0.035	2.974LysGly: 2.974 ± 0.058	0.772LysHis: 0.772 ± 0.027	1.729LysIle: 1.729 ± 0.045	2.232LysLys: 2.232 ± 0.064	3.399LysLeu: 3.399 ± 0.071	0.998LysMet: 0.998 ± 0.031	1.334LysAsn: 1.334 ± 0.034	1.71LysPro: 1.71 ± 0.041	1.445LysGln: 1.445 ± 0.041	2.29LysArg: 2.29 ± 0.048	1.929LysSer: 1.929 ± 0.046	2.187LysThr: 2.187 ± 0.05	2.643LysVal: 2.643 ± 0.057	0.333LysTrp: 0.333 ± 0.018	0.89LysTyr: 0.89 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	11.38LeuAla: 11.38 ± 0.128	1.657LeuCys: 1.657 ± 0.041	5.858LeuAsp: 5.858 ± 0.086	6.637LeuGlu: 6.637 ± 0.091	4.07LeuPhe: 4.07 ± 0.07	7.643LeuGly: 7.643 ± 0.092	2.62LeuHis: 2.62 ± 0.056	3.986LeuIle: 3.986 ± 0.079	3.931LeuLys: 3.931 ± 0.064	11.062LeuLeu: 11.062 ± 0.121	2.526LeuMet: 2.526 ± 0.049	2.766LeuAsn: 2.766 ± 0.051	5.664LeuPro: 5.664 ± 0.08	3.814LeuGln: 3.814 ± 0.065	7.586LeuArg: 7.586 ± 0.083	5.976LeuSer: 5.976 ± 0.084	5.561LeuThr: 5.561 ± 0.079	6.981LeuVal: 6.981 ± 0.094	1.16LeuTrp: 1.16 ± 0.041	2.605LeuTyr: 2.605 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	3.124MetAla: 3.124 ± 0.057	0.269MetCys: 0.269 ± 0.015	1.581MetAsp: 1.581 ± 0.04	1.789MetGlu: 1.789 ± 0.045	0.856MetPhe: 0.856 ± 0.033	2.134MetGly: 2.134 ± 0.041	0.784MetHis: 0.784 ± 0.028	1.054MetIle: 1.054 ± 0.034	1.242MetLys: 1.242 ± 0.038	3.334MetLeu: 3.334 ± 0.054	0.705MetMet: 0.705 ± 0.027	0.989MetAsn: 0.989 ± 0.033	1.622MetPro: 1.622 ± 0.041	1.373MetGln: 1.373 ± 0.033	1.984MetArg: 1.984 ± 0.044	1.563MetSer: 1.563 ± 0.04	1.748MetThr: 1.748 ± 0.044	1.929MetVal: 1.929 ± 0.046	0.248MetTrp: 0.248 ± 0.015	0.599MetTyr: 0.599 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	3.087AsnAla: 3.087 ± 0.057	0.396AsnCys: 0.396 ± 0.021	1.434AsnAsp: 1.434 ± 0.037	1.483AsnGlu: 1.483 ± 0.037	0.98AsnPhe: 0.98 ± 0.031	2.238AsnGly: 2.238 ± 0.046	0.588AsnHis: 0.588 ± 0.023	1.795AsnIle: 1.795 ± 0.039	1.041AsnLys: 1.041 ± 0.033	2.831AsnLeu: 2.831 ± 0.06	0.873AsnMet: 0.873 ± 0.028	0.856AsnAsn: 0.856 ± 0.033	1.777AsnPro: 1.777 ± 0.043	0.72AsnGln: 0.72 ± 0.026	1.874AsnArg: 1.874 ± 0.047	1.38AsnSer: 1.38 ± 0.038	1.531AsnThr: 1.531 ± 0.038	2.127AsnVal: 2.127 ± 0.042	0.329AsnTrp: 0.329 ± 0.017	0.713AsnTyr: 0.713 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.366ProAla: 6.366 ± 0.107	0.714ProCys: 0.714 ± 0.031	3.468ProAsp: 3.468 ± 0.067	4.051ProGlu: 4.051 ± 0.062	1.916ProPhe: 1.916 ± 0.048	3.374ProGly: 3.374 ± 0.057	1.218ProHis: 1.218 ± 0.033	1.224ProIle: 1.224 ± 0.034	1.144ProLys: 1.144 ± 0.039	4.83ProLeu: 4.83 ± 0.078	1.067ProMet: 1.067 ± 0.031	0.897ProAsn: 0.897 ± 0.032	2.252ProPro: 2.252 ± 0.053	2.228ProGln: 2.228 ± 0.047	2.779ProArg: 2.779 ± 0.056	2.269ProSer: 2.269 ± 0.045	1.497ProThr: 1.497 ± 0.037	4.899ProVal: 4.899 ± 0.08	0.638ProTrp: 0.638 ± 0.026	1.28ProTyr: 1.28 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.462GlnAla: 4.462 ± 0.075	0.445GlnCys: 0.445 ± 0.02	1.852GlnAsp: 1.852 ± 0.041	2.41GlnGlu: 2.41 ± 0.055	1.07GlnPhe: 1.07 ± 0.033	2.886GlnGly: 2.886 ± 0.057	0.927GlnHis: 0.927 ± 0.035	1.56GlnIle: 1.56 ± 0.032	1.499GlnLys: 1.499 ± 0.042	3.324GlnLeu: 3.324 ± 0.055	0.985GlnMet: 0.985 ± 0.031	1.128GlnAsn: 1.128 ± 0.034	1.717GlnPro: 1.717 ± 0.045	1.935GlnGln: 1.935 ± 0.053	2.465GlnArg: 2.465 ± 0.061	1.837GlnSer: 1.837 ± 0.046	1.936GlnThr: 1.936 ± 0.045	2.453GlnVal: 2.453 ± 0.042	0.439GlnTrp: 0.439 ± 0.019	0.857GlnTyr: 0.857 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	5.774ArgAla: 5.774 ± 0.08	1.016ArgCys: 1.016 ± 0.036	3.434ArgAsp: 3.434 ± 0.068	4.347ArgGlu: 4.347 ± 0.07	2.836ArgPhe: 2.836 ± 0.055	4.322ArgGly: 4.322 ± 0.067	2.044ArgHis: 2.044 ± 0.047	3.906ArgIle: 3.906 ± 0.06	3.034ArgLys: 3.034 ± 0.055	7.633ArgLeu: 7.633 ± 0.093	2.261ArgMet: 2.261 ± 0.046	2.182ArgAsn: 2.182 ± 0.049	3.03ArgPro: 3.03 ± 0.066	3.135ArgGln: 3.135 ± 0.055	5.476ArgArg: 5.476 ± 0.093	3.802ArgSer: 3.802 ± 0.062	3.784ArgThr: 3.784 ± 0.06	4.271ArgVal: 4.271 ± 0.068	0.897ArgTrp: 0.897 ± 0.029	2.077ArgTyr: 2.077 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.805SerAla: 5.805 ± 0.089	0.82SerCys: 0.82 ± 0.034	2.604SerAsp: 2.604 ± 0.051	2.709SerGlu: 2.709 ± 0.058	2.388SerPhe: 2.388 ± 0.049	5.967SerGly: 5.967 ± 0.089	1.109SerHis: 1.109 ± 0.03	2.744SerIle: 2.744 ± 0.048	1.596SerLys: 1.596 ± 0.041	5.942SerLeu: 5.942 ± 0.078	1.707SerMet: 1.707 ± 0.037	1.251SerAsn: 1.251 ± 0.041	2.694SerPro: 2.694 ± 0.051	1.564SerGln: 1.564 ± 0.04	3.884SerArg: 3.884 ± 0.065	3.175SerSer: 3.175 ± 0.065	2.518SerThr: 2.518 ± 0.055	4.381SerVal: 4.381 ± 0.069	0.679SerTrp: 0.679 ± 0.026	1.362SerTyr: 1.362 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	6.276ThrAla: 6.276 ± 0.085	0.656ThrCys: 0.656 ± 0.025	2.701ThrAsp: 2.701 ± 0.048	2.854ThrGlu: 2.854 ± 0.053	1.86ThrPhe: 1.86 ± 0.042	5.692ThrGly: 5.692 ± 0.078	1.059ThrHis: 1.059 ± 0.032	2.541ThrIle: 2.541 ± 0.06	1.33ThrLys: 1.33 ± 0.044	5.845ThrLeu: 5.845 ± 0.092	1.383ThrMet: 1.383 ± 0.031	1.173ThrAsn: 1.173 ± 0.033	3.295ThrPro: 3.295 ± 0.059	1.637ThrGln: 1.637 ± 0.038	3.3ThrArg: 3.3 ± 0.056	2.501ThrSer: 2.501 ± 0.051	2.553ThrThr: 2.553 ± 0.054	4.663ThrVal: 4.663 ± 0.074	0.521ThrTrp: 0.521 ± 0.024	1.24ThrTyr: 1.24 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	7.184ValAla: 7.184 ± 0.091	1.137ValCys: 1.137 ± 0.033	3.847ValAsp: 3.847 ± 0.07	4.322ValGlu: 4.322 ± 0.073	3.179ValPhe: 3.179 ± 0.056	4.518ValGly: 4.518 ± 0.086	1.747ValHis: 1.747 ± 0.045	3.743ValIle: 3.743 ± 0.061	2.474ValLys: 2.474 ± 0.049	8.539ValLeu: 8.539 ± 0.094	2.16ValMet: 2.16 ± 0.051	2.18ValAsn: 2.18 ± 0.047	3.798ValPro: 3.798 ± 0.067	2.838ValGln: 2.838 ± 0.054	5.611ValArg: 5.611 ± 0.077	4.541ValSer: 4.541 ± 0.071	4.471ValThr: 4.471 ± 0.078	5.857ValVal: 5.857 ± 0.09	0.868ValTrp: 0.868 ± 0.035	1.874ValTyr: 1.874 ± 0.047	0.0ValXaa: 0.0 ± 0.0
Trp	1.007TrpAla: 1.007 ± 0.032	0.177TrpCys: 0.177 ± 0.013	0.63TrpAsp: 0.63 ± 0.026	0.641TrpGlu: 0.641 ± 0.024	0.466TrpPhe: 0.466 ± 0.02	0.762TrpGly: 0.762 ± 0.031	0.35TrpHis: 0.35 ± 0.018	0.509TrpIle: 0.509 ± 0.027	0.507TrpLys: 0.507 ± 0.023	1.493TrpLeu: 1.493 ± 0.047	0.32TrpMet: 0.32 ± 0.017	0.461TrpAsn: 0.461 ± 0.022	0.577TrpPro: 0.577 ± 0.026	0.673TrpGln: 0.673 ± 0.026	0.856TrpArg: 0.856 ± 0.035	0.603TrpSer: 0.603 ± 0.021	0.606TrpThr: 0.606 ± 0.026	0.706TrpVal: 0.706 ± 0.028	0.185TrpTrp: 0.185 ± 0.013	0.265TrpTyr: 0.265 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.52TyrAla: 2.52 ± 0.05	0.405TyrCys: 0.405 ± 0.018	1.592TyrAsp: 1.592 ± 0.038	1.438TyrGlu: 1.438 ± 0.037	1.091TyrPhe: 1.091 ± 0.036	2.231TyrGly: 2.231 ± 0.052	0.574TyrHis: 0.574 ± 0.025	1.168TyrIle: 1.168 ± 0.031	0.883TyrLys: 0.883 ± 0.033	2.622TyrLeu: 2.622 ± 0.047	0.632TyrMet: 0.632 ± 0.023	0.822TyrAsn: 0.822 ± 0.032	1.252TyrPro: 1.252 ± 0.032	0.734TyrGln: 0.734 ± 0.026	1.949TyrArg: 1.949 ± 0.045	1.527TyrSer: 1.527 ± 0.045	1.489TyrThr: 1.489 ± 0.04	1.717TyrVal: 1.717 ± 0.044	0.373TyrTrp: 0.373 ± 0.018	0.86TyrTyr: 0.86 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3220 proteins (1069418 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---