Amino acid dipepetide frequency for Sinirhodobacter populi

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.255AlaAla: 18.255 ± 0.197	1.071AlaCys: 1.071 ± 0.028	6.913AlaAsp: 6.913 ± 0.078	8.5AlaGlu: 8.5 ± 0.097	4.391AlaPhe: 4.391 ± 0.062	11.64AlaGly: 11.64 ± 0.127	2.35AlaHis: 2.35 ± 0.049	6.132AlaIle: 6.132 ± 0.083	3.545AlaLys: 3.545 ± 0.074	14.46AlaLeu: 14.46 ± 0.152	3.804AlaMet: 3.804 ± 0.061	2.5AlaAsn: 2.5 ± 0.047	6.493AlaPro: 6.493 ± 0.09	4.532AlaGln: 4.532 ± 0.064	10.213AlaArg: 10.213 ± 0.116	5.484AlaSer: 5.484 ± 0.073	6.081AlaThr: 6.081 ± 0.07	8.921AlaVal: 8.921 ± 0.089	1.469AlaTrp: 1.469 ± 0.038	2.418AlaTyr: 2.418 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.097CysAla: 1.097 ± 0.032	0.117CysCys: 0.117 ± 0.011	0.554CysAsp: 0.554 ± 0.021	0.448CysGlu: 0.448 ± 0.02	0.307CysPhe: 0.307 ± 0.013	0.907CysGly: 0.907 ± 0.03	0.258CysHis: 0.258 ± 0.014	0.369CysIle: 0.369 ± 0.017	0.162CysLys: 0.162 ± 0.011	0.911CysLeu: 0.911 ± 0.025	0.142CysMet: 0.142 ± 0.011	0.18CysAsn: 0.18 ± 0.01	0.482CysPro: 0.482 ± 0.02	0.205CysGln: 0.205 ± 0.012	0.624CysArg: 0.624 ± 0.023	0.418CysSer: 0.418 ± 0.017	0.397CysThr: 0.397 ± 0.016	0.559CysVal: 0.559 ± 0.021	0.123CysTrp: 0.123 ± 0.01	0.182CysTyr: 0.182 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.724AspAla: 6.724 ± 0.088	0.469AspCys: 0.469 ± 0.02	2.91AspAsp: 2.91 ± 0.058	3.131AspGlu: 3.131 ± 0.056	2.318AspPhe: 2.318 ± 0.047	5.072AspGly: 5.072 ± 0.078	1.325AspHis: 1.325 ± 0.031	2.841AspIle: 2.841 ± 0.05	1.415AspLys: 1.415 ± 0.038	6.687AspLeu: 6.687 ± 0.079	1.475AspMet: 1.475 ± 0.038	1.078AspAsn: 1.078 ± 0.027	4.026AspPro: 4.026 ± 0.058	1.69AspGln: 1.69 ± 0.033	4.659AspArg: 4.659 ± 0.082	2.028AspSer: 2.028 ± 0.045	2.751AspThr: 2.751 ± 0.049	3.711AspVal: 3.711 ± 0.06	1.19AspTrp: 1.19 ± 0.028	1.591AspTyr: 1.591 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	8.22GluAla: 8.22 ± 0.112	0.331GluCys: 0.331 ± 0.017	3.01GluAsp: 3.01 ± 0.051	3.226GluGlu: 3.226 ± 0.072	1.704GluPhe: 1.704 ± 0.039	4.967GluGly: 4.967 ± 0.066	1.025GluHis: 1.025 ± 0.03	3.46GluIle: 3.46 ± 0.056	1.947GluLys: 1.947 ± 0.054	4.765GluLeu: 4.765 ± 0.061	1.659GluMet: 1.659 ± 0.037	1.535GluAsn: 1.535 ± 0.037	2.669GluPro: 2.669 ± 0.044	1.807GluGln: 1.807 ± 0.04	4.276GluArg: 4.276 ± 0.072	2.001GluSer: 2.001 ± 0.04	3.592GluThr: 3.592 ± 0.057	4.204GluVal: 4.204 ± 0.068	0.697GluTrp: 0.697 ± 0.023	1.019GluTyr: 1.019 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.527PheAla: 4.527 ± 0.063	0.398PheCys: 0.398 ± 0.018	2.655PheAsp: 2.655 ± 0.043	1.9PheGlu: 1.9 ± 0.042	1.315PhePhe: 1.315 ± 0.038	3.871PheGly: 3.871 ± 0.064	0.731PheHis: 0.731 ± 0.025	1.674PheIle: 1.674 ± 0.04	0.735PheLys: 0.735 ± 0.027	3.494PheLeu: 3.494 ± 0.065	0.776PheMet: 0.776 ± 0.028	0.934PheAsn: 0.934 ± 0.024	1.651PhePro: 1.651 ± 0.038	0.935PheGln: 0.935 ± 0.029	2.434PheArg: 2.434 ± 0.043	2.13PheSer: 2.13 ± 0.043	2.113PheThr: 2.113 ± 0.043	2.654PheVal: 2.654 ± 0.045	0.585PheTrp: 0.585 ± 0.02	0.838PheTyr: 0.838 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	10.459GlyAla: 10.459 ± 0.109	0.849GlyCys: 0.849 ± 0.028	4.412GlyAsp: 4.412 ± 0.057	4.753GlyGlu: 4.753 ± 0.065	3.688GlyPhe: 3.688 ± 0.053	7.552GlyGly: 7.552 ± 0.098	1.916GlyHis: 1.916 ± 0.039	4.912GlyIle: 4.912 ± 0.064	3.089GlyLys: 3.089 ± 0.065	9.631GlyLeu: 9.631 ± 0.076	2.598GlyMet: 2.598 ± 0.042	2.12GlyAsn: 2.12 ± 0.05	4.059GlyPro: 4.059 ± 0.062	3.06GlyGln: 3.06 ± 0.051	6.747GlyArg: 6.747 ± 0.083	4.15GlySer: 4.15 ± 0.065	4.827GlyThr: 4.827 ± 0.074	6.638GlyVal: 6.638 ± 0.076	1.603GlyTrp: 1.603 ± 0.037	2.341GlyTyr: 2.341 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.383HisAla: 2.383 ± 0.045	0.21HisCys: 0.21 ± 0.013	1.277HisAsp: 1.277 ± 0.033	1.069HisGlu: 1.069 ± 0.028	0.835HisPhe: 0.835 ± 0.029	1.845HisGly: 1.845 ± 0.036	0.522HisHis: 0.522 ± 0.026	0.891HisIle: 0.891 ± 0.024	0.44HisLys: 0.44 ± 0.017	2.125HisLeu: 2.125 ± 0.045	0.523HisMet: 0.523 ± 0.021	0.4HisAsn: 0.4 ± 0.016	1.487HisPro: 1.487 ± 0.034	0.525HisGln: 0.525 ± 0.022	1.499HisArg: 1.499 ± 0.034	0.865HisSer: 0.865 ± 0.025	0.723HisThr: 0.723 ± 0.022	1.468HisVal: 1.468 ± 0.037	0.352HisTrp: 0.352 ± 0.016	0.514HisTyr: 0.514 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.698IleAla: 7.698 ± 0.092	0.598IleCys: 0.598 ± 0.022	3.384IleAsp: 3.384 ± 0.054	3.391IleGlu: 3.391 ± 0.052	1.792IlePhe: 1.792 ± 0.038	5.219IleGly: 5.219 ± 0.069	0.92IleHis: 0.92 ± 0.031	2.005IleIle: 2.005 ± 0.046	1.02IleLys: 1.02 ± 0.032	4.908IleLeu: 4.908 ± 0.071	0.986IleMet: 0.986 ± 0.029	1.208IleAsn: 1.208 ± 0.035	2.501IlePro: 2.501 ± 0.043	1.051IleGln: 1.051 ± 0.028	3.8IleArg: 3.8 ± 0.057	2.984IleSer: 2.984 ± 0.049	2.798IleThr: 2.798 ± 0.043	4.089IleVal: 4.089 ± 0.065	0.675IleTrp: 0.675 ± 0.027	1.121IleTyr: 1.121 ± 0.034	0.0IleXaa: 0.0 ± 0.0
Lys	3.748LysAla: 3.748 ± 0.061	0.148LysCys: 0.148 ± 0.011	1.475LysAsp: 1.475 ± 0.037	1.361LysGlu: 1.361 ± 0.036	0.832LysPhe: 0.832 ± 0.029	2.532LysGly: 2.532 ± 0.046	0.482LysHis: 0.482 ± 0.019	1.575LysIle: 1.575 ± 0.038	0.991LysLys: 0.991 ± 0.035	2.69LysLeu: 2.69 ± 0.052	0.784LysMet: 0.784 ± 0.028	0.696LysAsn: 0.696 ± 0.031	1.679LysPro: 1.679 ± 0.044	0.746LysGln: 0.746 ± 0.027	1.937LysArg: 1.937 ± 0.045	1.561LysSer: 1.561 ± 0.046	1.745LysThr: 1.745 ± 0.039	2.276LysVal: 2.276 ± 0.047	0.353LysTrp: 0.353 ± 0.016	0.612LysTyr: 0.612 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	14.0LeuAla: 14.0 ± 0.138	0.988LeuCys: 0.988 ± 0.027	6.109LeuAsp: 6.109 ± 0.073	4.732LeuGlu: 4.732 ± 0.068	3.557LeuPhe: 3.557 ± 0.062	8.593LeuGly: 8.593 ± 0.098	2.003LeuHis: 2.003 ± 0.038	5.62LeuIle: 5.62 ± 0.076	3.095LeuLys: 3.095 ± 0.056	9.254LeuLeu: 9.254 ± 0.119	2.635LeuMet: 2.635 ± 0.05	2.598LeuAsn: 2.598 ± 0.044	6.117LeuPro: 6.117 ± 0.075	2.473LeuGln: 2.473 ± 0.044	8.086LeuArg: 8.086 ± 0.102	6.417LeuSer: 6.417 ± 0.068	6.199LeuThr: 6.199 ± 0.069	6.897LeuVal: 6.897 ± 0.079	1.339LeuTrp: 1.339 ± 0.038	1.907LeuTyr: 1.907 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	3.45MetAla: 3.45 ± 0.053	0.159MetCys: 0.159 ± 0.01	1.267MetAsp: 1.267 ± 0.031	1.253MetGlu: 1.253 ± 0.03	0.747MetPhe: 0.747 ± 0.025	2.081MetGly: 2.081 ± 0.039	0.395MetHis: 0.395 ± 0.019	1.536MetIle: 1.536 ± 0.035	0.981MetLys: 0.981 ± 0.03	2.625MetLeu: 2.625 ± 0.05	0.717MetMet: 0.717 ± 0.029	0.822MetAsn: 0.822 ± 0.025	1.551MetPro: 1.551 ± 0.037	0.896MetGln: 0.896 ± 0.027	2.005MetArg: 2.005 ± 0.04	1.62MetSer: 1.62 ± 0.038	2.203MetThr: 2.203 ± 0.038	1.801MetVal: 1.801 ± 0.036	0.22MetTrp: 0.22 ± 0.013	0.295MetTyr: 0.295 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.948AsnAla: 2.948 ± 0.048	0.222AsnCys: 0.222 ± 0.013	1.325AsnAsp: 1.325 ± 0.041	1.055AsnGlu: 1.055 ± 0.029	0.884AsnPhe: 0.884 ± 0.027	2.26AsnGly: 2.26 ± 0.047	0.447AsnHis: 0.447 ± 0.019	1.291AsnIle: 1.291 ± 0.033	0.512AsnLys: 0.512 ± 0.022	2.418AsnLeu: 2.418 ± 0.044	0.632AsnMet: 0.632 ± 0.024	0.569AsnAsn: 0.569 ± 0.022	1.764AsnPro: 1.764 ± 0.04	0.63AsnGln: 0.63 ± 0.023	1.751AsnArg: 1.751 ± 0.035	1.048AsnSer: 1.048 ± 0.033	1.261AsnThr: 1.261 ± 0.031	1.691AsnVal: 1.691 ± 0.039	0.455AsnTrp: 0.455 ± 0.019	0.578AsnTyr: 0.578 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	7.0ProAla: 7.0 ± 0.08	0.356ProCys: 0.356 ± 0.016	4.059ProAsp: 4.059 ± 0.065	4.435ProGlu: 4.435 ± 0.064	2.021ProPhe: 2.021 ± 0.046	5.3ProGly: 5.3 ± 0.071	1.139ProHis: 1.139 ± 0.031	2.102ProIle: 2.102 ± 0.047	1.555ProLys: 1.555 ± 0.034	4.919ProLeu: 4.919 ± 0.068	1.339ProMet: 1.339 ± 0.033	1.186ProAsn: 1.186 ± 0.031	2.651ProPro: 2.651 ± 0.046	1.718ProGln: 1.718 ± 0.041	3.238ProArg: 3.238 ± 0.05	2.351ProSer: 2.351 ± 0.044	2.351ProThr: 2.351 ± 0.043	4.995ProVal: 4.995 ± 0.064	0.74ProTrp: 0.74 ± 0.026	1.126ProTyr: 1.126 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	4.064GlnAla: 4.064 ± 0.061	0.189GlnCys: 0.189 ± 0.012	1.482GlnAsp: 1.482 ± 0.028	1.437GlnGlu: 1.437 ± 0.032	0.924GlnPhe: 0.924 ± 0.027	2.638GlnGly: 2.638 ± 0.046	0.524GlnHis: 0.524 ± 0.023	2.024GlnIle: 2.024 ± 0.04	0.979GlnLys: 0.979 ± 0.031	2.591GlnLeu: 2.591 ± 0.046	1.018GlnMet: 1.018 ± 0.026	0.845GlnAsn: 0.845 ± 0.028	1.611GlnPro: 1.611 ± 0.039	1.065GlnGln: 1.065 ± 0.034	2.146GlnArg: 2.146 ± 0.043	1.645GlnSer: 1.645 ± 0.034	1.611GlnThr: 1.611 ± 0.034	2.289GlnVal: 2.289 ± 0.039	0.378GlnTrp: 0.378 ± 0.018	0.6GlnTyr: 0.6 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	9.173ArgAla: 9.173 ± 0.107	0.498ArgCys: 0.498 ± 0.021	4.434ArgAsp: 4.434 ± 0.079	4.095ArgGlu: 4.095 ± 0.057	2.87ArgPhe: 2.87 ± 0.045	5.397ArgGly: 5.397 ± 0.065	1.762ArgHis: 1.762 ± 0.037	4.53ArgIle: 4.53 ± 0.066	2.206ArgLys: 2.206 ± 0.05	8.315ArgLeu: 8.315 ± 0.101	2.177ArgMet: 2.177 ± 0.038	1.898ArgAsn: 1.898 ± 0.042	3.864ArgPro: 3.864 ± 0.061	2.434ArgGln: 2.434 ± 0.05	5.969ArgArg: 5.969 ± 0.077	3.2ArgSer: 3.2 ± 0.06	3.238ArgThr: 3.238 ± 0.054	4.992ArgVal: 4.992 ± 0.068	1.005ArgTrp: 1.005 ± 0.03	1.646ArgTyr: 1.646 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.829SerAla: 5.829 ± 0.074	0.398SerCys: 0.398 ± 0.019	2.765SerAsp: 2.765 ± 0.049	2.418SerGlu: 2.418 ± 0.049	2.13SerPhe: 2.13 ± 0.042	5.524SerGly: 5.524 ± 0.081	1.012SerHis: 1.012 ± 0.028	2.319SerIle: 2.319 ± 0.045	1.221SerLys: 1.221 ± 0.034	5.004SerLeu: 5.004 ± 0.068	1.178SerMet: 1.178 ± 0.033	1.129SerAsn: 1.129 ± 0.034	2.557SerPro: 2.557 ± 0.043	1.443SerGln: 1.443 ± 0.038	3.428SerArg: 3.428 ± 0.055	2.441SerSer: 2.441 ± 0.051	2.448SerThr: 2.448 ± 0.056	3.803SerVal: 3.803 ± 0.055	0.725SerTrp: 0.725 ± 0.023	1.263SerTyr: 1.263 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	6.517ThrAla: 6.517 ± 0.074	0.475ThrCys: 0.475 ± 0.021	3.036ThrAsp: 3.036 ± 0.053	2.935ThrGlu: 2.935 ± 0.046	1.911ThrPhe: 1.911 ± 0.042	5.51ThrGly: 5.51 ± 0.072	1.04ThrHis: 1.04 ± 0.029	2.844ThrIle: 2.844 ± 0.053	1.285ThrLys: 1.285 ± 0.029	5.968ThrLeu: 5.968 ± 0.064	1.179ThrMet: 1.179 ± 0.031	1.171ThrAsn: 1.171 ± 0.036	3.577ThrPro: 3.577 ± 0.051	1.468ThrGln: 1.468 ± 0.029	3.584ThrArg: 3.584 ± 0.046	2.528ThrSer: 2.528 ± 0.052	2.768ThrThr: 2.768 ± 0.051	4.387ThrVal: 4.387 ± 0.059	0.636ThrTrp: 0.636 ± 0.023	1.085ThrTyr: 1.085 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	9.291ValAla: 9.291 ± 0.093	0.618ValCys: 0.618 ± 0.024	3.719ValAsp: 3.719 ± 0.058	4.204ValGlu: 4.204 ± 0.064	2.763ValPhe: 2.763 ± 0.05	5.366ValGly: 5.366 ± 0.075	1.261ValHis: 1.261 ± 0.032	4.412ValIle: 4.412 ± 0.063	2.035ValLys: 2.035 ± 0.049	7.91ValLeu: 7.91 ± 0.085	2.116ValMet: 2.116 ± 0.038	1.872ValAsn: 1.872 ± 0.04	3.977ValPro: 3.977 ± 0.057	2.098ValGln: 2.098 ± 0.037	4.464ValArg: 4.464 ± 0.061	4.268ValSer: 4.268 ± 0.069	4.983ValThr: 4.983 ± 0.057	5.645ValVal: 5.645 ± 0.082	0.991ValTrp: 0.991 ± 0.031	1.378ValTyr: 1.378 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	1.298TrpAla: 1.298 ± 0.037	0.124TrpCys: 0.124 ± 0.011	0.745TrpAsp: 0.745 ± 0.025	0.628TrpGlu: 0.628 ± 0.021	0.563TrpPhe: 0.563 ± 0.02	1.041TrpGly: 1.041 ± 0.032	0.349TrpHis: 0.349 ± 0.015	0.73TrpIle: 0.73 ± 0.029	0.493TrpLys: 0.493 ± 0.021	1.781TrpLeu: 1.781 ± 0.046	0.401TrpMet: 0.401 ± 0.017	0.442TrpAsn: 0.442 ± 0.02	0.744TrpPro: 0.744 ± 0.024	0.628TrpGln: 0.628 ± 0.021	1.188TrpArg: 1.188 ± 0.033	0.828TrpSer: 0.828 ± 0.028	0.773TrpThr: 0.773 ± 0.024	0.855TrpVal: 0.855 ± 0.025	0.222TrpTrp: 0.222 ± 0.017	0.278TrpTyr: 0.278 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.493TyrAla: 2.493 ± 0.047	0.222TyrCys: 0.222 ± 0.014	1.558TyrAsp: 1.558 ± 0.039	1.142TyrGlu: 1.142 ± 0.03	0.801TyrPhe: 0.801 ± 0.027	2.09TyrGly: 2.09 ± 0.042	0.492TyrHis: 0.492 ± 0.02	0.881TyrIle: 0.881 ± 0.027	0.517TyrLys: 0.517 ± 0.02	2.16TyrLeu: 2.16 ± 0.044	0.486TyrMet: 0.486 ± 0.023	0.558TyrAsn: 0.558 ± 0.02	1.124TyrPro: 1.124 ± 0.027	0.654TyrGln: 0.654 ± 0.025	1.658TyrArg: 1.658 ± 0.038	1.068TyrSer: 1.068 ± 0.029	1.044TyrThr: 1.044 ± 0.031	1.494TyrVal: 1.494 ± 0.035	0.353TyrTrp: 0.353 ± 0.017	0.558TyrTyr: 0.558 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4081 proteins (1300073 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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