Amino acid dipepetide frequency for Oryza meyeriana var. granulata

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.417AlaAla: 14.417 ± 0.068	1.636AlaCys: 1.636 ± 0.012	4.4AlaAsp: 4.4 ± 0.02	5.179AlaGlu: 5.179 ± 0.023	3.01AlaPhe: 3.01 ± 0.019	7.061AlaGly: 7.061 ± 0.029	1.809AlaHis: 1.809 ± 0.012	3.682AlaIle: 3.682 ± 0.017	3.857AlaLys: 3.857 ± 0.019	8.012AlaLeu: 8.012 ± 0.031	2.445AlaMet: 2.445 ± 0.014	2.601AlaAsn: 2.601 ± 0.015	5.004AlaPro: 5.004 ± 0.025	2.554AlaGln: 2.554 ± 0.016	5.711AlaArg: 5.711 ± 0.022	7.712AlaSer: 7.712 ± 0.026	5.113AlaThr: 5.113 ± 0.021	7.154AlaVal: 7.154 ± 0.029	1.1AlaTrp: 1.1 ± 0.009	1.926AlaTyr: 1.926 ± 0.013	0.003AlaXaa: 0.003 ± 0.0
Cys	1.387CysAla: 1.387 ± 0.011	0.607CysCys: 0.607 ± 0.009	0.876CysAsp: 0.876 ± 0.008	0.796CysGlu: 0.796 ± 0.007	0.785CysPhe: 0.785 ± 0.008	1.558CysGly: 1.558 ± 0.012	0.535CysHis: 0.535 ± 0.007	0.88CysIle: 0.88 ± 0.009	0.907CysLys: 0.907 ± 0.008	1.789CysLeu: 1.789 ± 0.012	0.474CysMet: 0.474 ± 0.006	0.708CysAsn: 0.708 ± 0.007	0.991CysPro: 0.991 ± 0.01	0.574CysGln: 0.574 ± 0.007	1.379CysArg: 1.379 ± 0.011	1.874CysSer: 1.874 ± 0.013	0.945CysThr: 0.945 ± 0.009	1.117CysVal: 1.117 ± 0.009	0.26CysTrp: 0.26 ± 0.005	0.525CysTyr: 0.525 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	4.86AspAla: 4.86 ± 0.019	0.869AspCys: 0.869 ± 0.009	4.241AspAsp: 4.241 ± 0.025	3.993AspGlu: 3.993 ± 0.02	1.927AspPhe: 1.927 ± 0.014	4.87AspGly: 4.87 ± 0.021	1.261AspHis: 1.261 ± 0.01	2.578AspIle: 2.578 ± 0.014	2.42AspLys: 2.42 ± 0.013	4.762AspLeu: 4.762 ± 0.021	1.405AspMet: 1.405 ± 0.011	1.805AspAsn: 1.805 ± 0.013	2.711AspPro: 2.711 ± 0.015	1.605AspGln: 1.605 ± 0.012	2.788AspArg: 2.788 ± 0.015	3.636AspSer: 3.636 ± 0.017	2.239AspThr: 2.239 ± 0.012	3.823AspVal: 3.823 ± 0.018	0.698AspTrp: 0.698 ± 0.008	1.376AspTyr: 1.376 ± 0.012	0.001AspXaa: 0.001 ± 0.0
Glu	5.733GluAla: 5.733 ± 0.026	0.85GluCys: 0.85 ± 0.008	3.709GluAsp: 3.709 ± 0.018	5.938GluGlu: 5.938 ± 0.034	1.962GluPhe: 1.962 ± 0.012	3.848GluGly: 3.848 ± 0.017	1.405GluHis: 1.405 ± 0.011	2.845GluIle: 2.845 ± 0.017	3.694GluLys: 3.694 ± 0.025	5.859GluLeu: 5.859 ± 0.023	1.686GluMet: 1.686 ± 0.011	2.161GluAsn: 2.161 ± 0.014	2.398GluPro: 2.398 ± 0.016	2.317GluGln: 2.317 ± 0.015	3.73GluArg: 3.73 ± 0.019	3.712GluSer: 3.712 ± 0.021	2.552GluThr: 2.552 ± 0.015	4.154GluVal: 4.154 ± 0.019	0.739GluTrp: 0.739 ± 0.008	1.478GluTyr: 1.478 ± 0.011	0.001GluXaa: 0.001 ± 0.0
Phe	2.773PheAla: 2.773 ± 0.015	0.759PheCys: 0.759 ± 0.008	2.11PheAsp: 2.11 ± 0.013	1.784PheGlu: 1.784 ± 0.011	1.626PhePhe: 1.626 ± 0.014	2.764PheGly: 2.764 ± 0.017	0.987PheHis: 0.987 ± 0.008	1.546PheIle: 1.546 ± 0.013	1.447PheLys: 1.447 ± 0.011	3.719PheLeu: 3.719 ± 0.02	0.849PheMet: 0.849 ± 0.009	1.212PheAsn: 1.212 ± 0.009	1.833PhePro: 1.833 ± 0.013	1.195PheGln: 1.195 ± 0.01	1.994PheArg: 1.994 ± 0.011	3.153PheSer: 3.153 ± 0.017	1.721PheThr: 1.721 ± 0.013	2.563PheVal: 2.563 ± 0.013	0.506PheTrp: 0.506 ± 0.006	1.043PheTyr: 1.043 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	6.498GlyAla: 6.498 ± 0.026	1.5GlyCys: 1.5 ± 0.013	4.255GlyAsp: 4.255 ± 0.021	4.302GlyGlu: 4.302 ± 0.021	2.79GlyPhe: 2.79 ± 0.016	8.673GlyGly: 8.673 ± 0.049	1.863GlyHis: 1.863 ± 0.012	3.046GlyIle: 3.046 ± 0.018	3.69GlyLys: 3.69 ± 0.018	6.018GlyLeu: 6.018 ± 0.023	1.751GlyMet: 1.751 ± 0.011	2.623GlyAsn: 2.623 ± 0.017	2.88GlyPro: 2.88 ± 0.016	2.214GlyGln: 2.214 ± 0.016	5.167GlyArg: 5.167 ± 0.023	6.247GlySer: 6.247 ± 0.023	3.505GlyThr: 3.505 ± 0.018	4.899GlyVal: 4.899 ± 0.021	1.085GlyTrp: 1.085 ± 0.01	1.991GlyTyr: 1.991 ± 0.012	0.002GlyXaa: 0.002 ± 0.0
His	1.966HisAla: 1.966 ± 0.012	0.541HisCys: 0.541 ± 0.007	1.253HisAsp: 1.253 ± 0.01	1.232HisGlu: 1.232 ± 0.009	0.894HisPhe: 0.894 ± 0.007	2.222HisGly: 2.222 ± 0.015	1.098HisHis: 1.098 ± 0.012	1.032HisIle: 1.032 ± 0.008	0.994HisLys: 0.994 ± 0.009	2.448HisLeu: 2.448 ± 0.015	0.591HisMet: 0.591 ± 0.007	0.767HisAsn: 0.767 ± 0.007	1.577HisPro: 1.577 ± 0.012	0.95HisGln: 0.95 ± 0.008	1.836HisArg: 1.836 ± 0.012	1.709HisSer: 1.709 ± 0.012	0.987HisThr: 0.987 ± 0.008	1.659HisVal: 1.659 ± 0.012	0.318HisTrp: 0.318 ± 0.005	0.653HisTyr: 0.653 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	3.522IleAla: 3.522 ± 0.018	0.927IleCys: 0.927 ± 0.009	2.453IleAsp: 2.453 ± 0.013	2.44IleGlu: 2.44 ± 0.015	1.638IlePhe: 1.638 ± 0.012	2.962IleGly: 2.962 ± 0.016	1.076IleHis: 1.076 ± 0.01	2.08IleIle: 2.08 ± 0.014	2.146IleLys: 2.146 ± 0.013	4.089IleLeu: 4.089 ± 0.022	1.002IleMet: 1.002 ± 0.01	1.586IleAsn: 1.586 ± 0.012	2.335IlePro: 2.335 ± 0.016	1.51IleGln: 1.51 ± 0.011	2.311IleArg: 2.311 ± 0.014	3.635IleSer: 3.635 ± 0.017	2.188IleThr: 2.188 ± 0.012	2.977IleVal: 2.977 ± 0.016	0.578IleTrp: 0.578 ± 0.007	1.178IleTyr: 1.178 ± 0.011	0.0IleXaa: 0.0 ± 0.0
Lys	3.926LysAla: 3.926 ± 0.02	0.768LysCys: 0.768 ± 0.008	2.668LysAsp: 2.668 ± 0.017	3.691LysGlu: 3.691 ± 0.022	1.527LysPhe: 1.527 ± 0.012	3.084LysGly: 3.084 ± 0.017	1.137LysHis: 1.137 ± 0.01	2.377LysIle: 2.377 ± 0.014	3.574LysLys: 3.574 ± 0.022	4.678LysLeu: 4.678 ± 0.019	1.261LysMet: 1.261 ± 0.009	1.878LysAsn: 1.878 ± 0.013	2.341LysPro: 2.341 ± 0.016	1.886LysGln: 1.886 ± 0.012	3.168LysArg: 3.168 ± 0.018	3.322LysSer: 3.322 ± 0.019	2.215LysThr: 2.215 ± 0.013	3.233LysVal: 3.233 ± 0.015	0.608LysTrp: 0.608 ± 0.007	1.274LysTyr: 1.274 ± 0.01	0.0LysXaa: 0.0 ± 0.0
Leu	8.384LeuAla: 8.384 ± 0.031	1.82LeuCys: 1.82 ± 0.013	4.925LeuAsp: 4.925 ± 0.02	5.545LeuGlu: 5.545 ± 0.025	3.324LeuPhe: 3.324 ± 0.02	5.999LeuGly: 5.999 ± 0.022	2.694LeuHis: 2.694 ± 0.017	3.495LeuIle: 3.495 ± 0.019	4.51LeuLys: 4.51 ± 0.023	10.321LeuLeu: 10.321 ± 0.039	2.038LeuMet: 2.038 ± 0.013	2.928LeuAsn: 2.928 ± 0.015	5.855LeuPro: 5.855 ± 0.023	3.91LeuGln: 3.91 ± 0.019	6.354LeuArg: 6.354 ± 0.022	7.478LeuSer: 7.478 ± 0.029	4.119LeuThr: 4.119 ± 0.019	6.476LeuVal: 6.476 ± 0.024	1.117LeuTrp: 1.117 ± 0.009	2.258LeuTyr: 2.258 ± 0.013	0.001LeuXaa: 0.001 ± 0.0
Met	2.965MetAla: 2.965 ± 0.015	0.351MetCys: 0.351 ± 0.005	1.493MetAsp: 1.493 ± 0.01	1.901MetGlu: 1.901 ± 0.011	0.739MetPhe: 0.739 ± 0.008	1.618MetGly: 1.618 ± 0.012	0.571MetHis: 0.571 ± 0.006	0.931MetIle: 0.931 ± 0.009	1.257MetLys: 1.257 ± 0.009	2.25MetLeu: 2.25 ± 0.012	0.678MetMet: 0.678 ± 0.007	0.829MetAsn: 0.829 ± 0.008	1.326MetPro: 1.326 ± 0.01	0.948MetGln: 0.948 ± 0.009	1.416MetArg: 1.416 ± 0.01	1.751MetSer: 1.751 ± 0.01	1.066MetThr: 1.066 ± 0.009	1.78MetVal: 1.78 ± 0.012	0.283MetTrp: 0.283 ± 0.005	0.582MetTyr: 0.582 ± 0.007	0.0MetXaa: 0.0 ± 0.0
Asn	2.638AsnAla: 2.638 ± 0.014	0.656AsnCys: 0.656 ± 0.006	1.701AsnAsp: 1.701 ± 0.013	1.82AsnGlu: 1.82 ± 0.015	1.316AsnPhe: 1.316 ± 0.01	2.802AsnGly: 2.802 ± 0.016	0.839AsnHis: 0.839 ± 0.009	1.826AsnIle: 1.826 ± 0.013	1.739AsnLys: 1.739 ± 0.013	3.328AsnLeu: 3.328 ± 0.018	0.927AsnMet: 0.927 ± 0.008	1.527AsnAsn: 1.527 ± 0.013	1.848AsnPro: 1.848 ± 0.013	1.208AsnGln: 1.208 ± 0.011	1.739AsnArg: 1.739 ± 0.011	2.761AsnSer: 2.761 ± 0.017	1.62AsnThr: 1.62 ± 0.012	2.227AsnVal: 2.227 ± 0.012	0.438AsnTrp: 0.438 ± 0.006	0.979AsnTyr: 0.979 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	5.625ProAla: 5.625 ± 0.026	0.993ProCys: 0.993 ± 0.009	2.735ProAsp: 2.735 ± 0.015	3.234ProGlu: 3.234 ± 0.02	1.86ProPhe: 1.86 ± 0.013	3.447ProGly: 3.447 ± 0.019	1.255ProHis: 1.255 ± 0.01	1.889ProIle: 1.889 ± 0.012	2.215ProLys: 2.215 ± 0.016	4.7ProLeu: 4.7 ± 0.021	1.15ProMet: 1.15 ± 0.009	1.771ProAsn: 1.771 ± 0.012	5.779ProPro: 5.779 ± 0.036	1.802ProGln: 1.802 ± 0.013	3.562ProArg: 3.562 ± 0.019	5.565ProSer: 5.565 ± 0.025	2.935ProThr: 2.935 ± 0.018	3.557ProVal: 3.557 ± 0.018	0.75ProTrp: 0.75 ± 0.008	1.278ProTyr: 1.278 ± 0.009	0.002ProXaa: 0.002 ± 0.0
Gln	2.748GlnAla: 2.748 ± 0.012	0.604GlnCys: 0.604 ± 0.007	1.573GlnAsp: 1.573 ± 0.012	2.328GlnGlu: 2.328 ± 0.015	1.121GlnPhe: 1.121 ± 0.009	2.179GlnGly: 2.179 ± 0.014	0.972GlnHis: 0.972 ± 0.009	1.543GlnIle: 1.543 ± 0.011	1.834GlnLys: 1.834 ± 0.014	3.463GlnLeu: 3.463 ± 0.018	0.938GlnMet: 0.938 ± 0.009	1.263GlnAsn: 1.263 ± 0.011	1.989GlnPro: 1.989 ± 0.015	2.173GlnGln: 2.173 ± 0.024	2.369GlnArg: 2.369 ± 0.014	2.431GlnSer: 2.431 ± 0.014	1.42GlnThr: 1.42 ± 0.01	2.154GlnVal: 2.154 ± 0.012	0.479GlnTrp: 0.479 ± 0.006	0.866GlnTyr: 0.866 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	5.357ArgAla: 5.357 ± 0.023	1.387ArgCys: 1.387 ± 0.011	3.022ArgAsp: 3.022 ± 0.017	3.62ArgGlu: 3.62 ± 0.018	2.203ArgPhe: 2.203 ± 0.013	4.633ArgGly: 4.633 ± 0.021	1.736ArgHis: 1.736 ± 0.012	2.578ArgIle: 2.578 ± 0.015	3.352ArgLys: 3.352 ± 0.017	6.106ArgLeu: 6.106 ± 0.024	1.583ArgMet: 1.583 ± 0.011	2.015ArgAsn: 2.015 ± 0.012	3.478ArgPro: 3.478 ± 0.018	2.207ArgGln: 2.207 ± 0.013	7.003ArgArg: 7.003 ± 0.032	5.104ArgSer: 5.104 ± 0.024	2.739ArgThr: 2.739 ± 0.014	3.848ArgVal: 3.848 ± 0.017	1.139ArgTrp: 1.139 ± 0.009	1.556ArgTyr: 1.556 ± 0.013	0.001ArgXaa: 0.001 ± 0.0
Ser	6.786SerAla: 6.786 ± 0.023	1.726SerCys: 1.726 ± 0.011	4.061SerAsp: 4.061 ± 0.02	4.014SerGlu: 4.014 ± 0.018	3.134SerPhe: 3.134 ± 0.017	6.184SerGly: 6.184 ± 0.024	1.808SerHis: 1.808 ± 0.011	3.45SerIle: 3.45 ± 0.015	3.734SerLys: 3.734 ± 0.021	7.463SerLeu: 7.463 ± 0.028	2.03SerMet: 2.03 ± 0.012	2.933SerAsn: 2.933 ± 0.017	5.219SerPro: 5.219 ± 0.027	2.427SerGln: 2.427 ± 0.016	4.868SerArg: 4.868 ± 0.021	10.189SerSer: 10.189 ± 0.044	4.513SerThr: 4.513 ± 0.02	4.897SerVal: 4.897 ± 0.02	1.133SerTrp: 1.133 ± 0.01	2.018SerTyr: 2.018 ± 0.014	0.001SerXaa: 0.001 ± 0.0
Thr	4.796ThrAla: 4.796 ± 0.021	0.91ThrCys: 0.91 ± 0.009	2.304ThrAsp: 2.304 ± 0.014	2.6ThrGlu: 2.6 ± 0.015	1.706ThrPhe: 1.706 ± 0.009	3.649ThrGly: 3.649 ± 0.017	0.973ThrHis: 0.973 ± 0.009	2.226ThrIle: 2.226 ± 0.015	2.196ThrLys: 2.196 ± 0.014	4.152ThrLeu: 4.152 ± 0.018	1.256ThrMet: 1.256 ± 0.011	1.652ThrAsn: 1.652 ± 0.012	2.957ThrPro: 2.957 ± 0.016	1.322ThrGln: 1.322 ± 0.011	2.649ThrArg: 2.649 ± 0.016	4.297ThrSer: 4.297 ± 0.019	3.163ThrThr: 3.163 ± 0.021	3.643ThrVal: 3.643 ± 0.019	0.63ThrTrp: 0.63 ± 0.006	1.241ThrTyr: 1.241 ± 0.01	0.001ThrXaa: 0.001 ± 0.0
Val	7.086ValAla: 7.086 ± 0.027	1.189ValCys: 1.189 ± 0.01	3.992ValAsp: 3.992 ± 0.019	4.267ValGlu: 4.267 ± 0.019	2.473ValPhe: 2.473 ± 0.015	4.631ValGly: 4.631 ± 0.019	1.684ValHis: 1.684 ± 0.011	2.871ValIle: 2.871 ± 0.015	3.105ValLys: 3.105 ± 0.015	6.636ValLeu: 6.636 ± 0.029	1.612ValMet: 1.612 ± 0.011	2.079ValAsn: 2.079 ± 0.014	3.731ValPro: 3.731 ± 0.021	2.343ValGln: 2.343 ± 0.015	3.898ValArg: 3.898 ± 0.016	5.056ValSer: 5.056 ± 0.019	3.405ValThr: 3.405 ± 0.016	5.808ValVal: 5.808 ± 0.025	0.829ValTrp: 0.829 ± 0.008	1.766ValTyr: 1.766 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	1.016TrpAla: 1.016 ± 0.009	0.276TrpCys: 0.276 ± 0.004	0.669TrpAsp: 0.669 ± 0.008	0.737TrpGlu: 0.737 ± 0.007	0.485TrpPhe: 0.485 ± 0.006	0.808TrpGly: 0.808 ± 0.008	0.329TrpHis: 0.329 ± 0.005	0.572TrpIle: 0.572 ± 0.006	0.743TrpLys: 0.743 ± 0.008	1.316TrpLeu: 1.316 ± 0.01	0.372TrpMet: 0.372 ± 0.005	0.549TrpAsn: 0.549 ± 0.006	0.665TrpPro: 0.665 ± 0.007	0.481TrpGln: 0.481 ± 0.005	1.197TrpArg: 1.197 ± 0.009	1.032TrpSer: 1.032 ± 0.009	0.672TrpThr: 0.672 ± 0.006	0.815TrpVal: 0.815 ± 0.007	0.297TrpTrp: 0.297 ± 0.005	0.329TrpTyr: 0.329 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.898TyrAla: 1.898 ± 0.011	0.598TyrCys: 0.598 ± 0.007	1.428TyrAsp: 1.428 ± 0.011	1.347TyrGlu: 1.347 ± 0.011	1.064TyrPhe: 1.064 ± 0.009	2.005TyrGly: 2.005 ± 0.013	0.696TyrHis: 0.696 ± 0.008	1.185TyrIle: 1.185 ± 0.011	1.204TyrLys: 1.204 ± 0.011	2.442TyrLeu: 2.442 ± 0.014	0.685TyrMet: 0.685 ± 0.008	1.053TyrAsn: 1.053 ± 0.01	1.185TyrPro: 1.185 ± 0.011	0.821TyrGln: 0.821 ± 0.008	1.53TyrArg: 1.53 ± 0.011	1.923TyrSer: 1.923 ± 0.013	1.203TyrThr: 1.203 ± 0.01	1.678TyrVal: 1.678 ± 0.013	0.372TyrTrp: 0.372 ± 0.005	0.898TyrTyr: 0.898 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.002XaaAla: 0.002 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.003XaaPro: 0.003 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.002XaaArg: 0.002 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.048XaaXaa: 0.048 ± 0.011

Statistics based on 44256 proteins (13918302 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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