Amino acid dipepetide frequency for Lymantria dispar cypovirus 1 (isolate Rao) (LdCPV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.805AlaAla: 4.805 ± 1.035
0.519AlaCys: 0.519 ± 0.231
4.675AlaAsp: 4.675 ± 0.383
4.156AlaGlu: 4.156 ± 0.786
2.727AlaPhe: 2.727 ± 0.487
4.156AlaGly: 4.156 ± 1.078
1.948AlaHis: 1.948 ± 0.445
4.026AlaIle: 4.026 ± 0.427
2.987AlaLys: 2.987 ± 0.549
8.312AlaLeu: 8.312 ± 0.783
1.818AlaMet: 1.818 ± 0.403
3.766AlaAsn: 3.766 ± 0.92
2.208AlaPro: 2.208 ± 0.547
2.597AlaGln: 2.597 ± 0.436
4.156AlaArg: 4.156 ± 0.712
6.623AlaSer: 6.623 ± 1.032
5.195AlaThr: 5.195 ± 0.857
5.584AlaVal: 5.584 ± 0.838
0.649AlaTrp: 0.649 ± 0.343
2.208AlaTyr: 2.208 ± 0.714
0.0AlaXaa: 0.0 ± 0.0
Cys
1.169CysAla: 1.169 ± 0.39
0.13CysCys: 0.13 ± 0.113
0.26CysAsp: 0.26 ± 0.178
0.26CysGlu: 0.26 ± 0.29
0.13CysPhe: 0.13 ± 0.13
0.519CysGly: 0.519 ± 0.265
0.13CysHis: 0.13 ± 0.13
0.26CysIle: 0.26 ± 0.188
0.13CysLys: 0.13 ± 0.13
0.519CysLeu: 0.519 ± 0.243
0.13CysMet: 0.13 ± 0.13
0.519CysAsn: 0.519 ± 0.304
0.39CysPro: 0.39 ± 0.235
0.39CysGln: 0.39 ± 0.149
0.26CysArg: 0.26 ± 0.225
0.649CysSer: 0.649 ± 0.32
0.649CysThr: 0.649 ± 0.211
0.519CysVal: 0.519 ± 0.326
0.0CysTrp: 0.0 ± 0.0
0.26CysTyr: 0.26 ± 0.159
0.0CysXaa: 0.0 ± 0.0
Asp
3.636AspAla: 3.636 ± 0.76
0.0AspCys: 0.0 ± 0.0
4.156AspAsp: 4.156 ± 0.531
4.935AspGlu: 4.935 ± 0.872
2.468AspPhe: 2.468 ± 0.481
3.377AspGly: 3.377 ± 0.487
1.558AspHis: 1.558 ± 0.481
5.714AspIle: 5.714 ± 0.585
1.558AspLys: 1.558 ± 0.344
4.805AspLeu: 4.805 ± 0.829
1.299AspMet: 1.299 ± 0.367
2.987AspAsn: 2.987 ± 0.428
2.468AspPro: 2.468 ± 0.626
1.558AspGln: 1.558 ± 0.557
2.468AspArg: 2.468 ± 0.51
2.468AspSer: 2.468 ± 0.447
3.896AspThr: 3.896 ± 0.989
5.195AspVal: 5.195 ± 0.785
0.39AspTrp: 0.39 ± 0.197
2.597AspTyr: 2.597 ± 0.433
0.0AspXaa: 0.0 ± 0.0
Glu
4.675GluAla: 4.675 ± 0.58
0.0GluCys: 0.0 ± 0.0
3.377GluAsp: 3.377 ± 0.462
1.688GluGlu: 1.688 ± 0.677
2.468GluPhe: 2.468 ± 0.42
3.117GluGly: 3.117 ± 0.615
1.039GluHis: 1.039 ± 0.402
4.156GluIle: 4.156 ± 0.897
2.597GluLys: 2.597 ± 0.424
6.104GluLeu: 6.104 ± 0.932
1.948GluMet: 1.948 ± 0.466
2.208GluAsn: 2.208 ± 0.571
1.429GluPro: 1.429 ± 0.429
3.636GluGln: 3.636 ± 0.469
3.117GluArg: 3.117 ± 0.445
4.286GluSer: 4.286 ± 0.672
3.377GluThr: 3.377 ± 0.626
3.377GluVal: 3.377 ± 0.625
0.13GluTrp: 0.13 ± 0.101
3.377GluTyr: 3.377 ± 0.515
0.0GluXaa: 0.0 ± 0.0
Phe
2.987PheAla: 2.987 ± 0.62
0.649PheCys: 0.649 ± 0.241
2.468PheAsp: 2.468 ± 0.505
2.597PheGlu: 2.597 ± 0.414
1.688PhePhe: 1.688 ± 0.465
1.688PheGly: 1.688 ± 0.383
0.779PheHis: 0.779 ± 0.242
2.338PheIle: 2.338 ± 0.484
2.727PheLys: 2.727 ± 0.477
3.766PheLeu: 3.766 ± 0.766
0.909PheMet: 0.909 ± 0.35
3.377PheAsn: 3.377 ± 0.451
1.818PhePro: 1.818 ± 0.414
1.039PheGln: 1.039 ± 0.335
2.078PheArg: 2.078 ± 0.288
3.247PheSer: 3.247 ± 0.469
2.857PheThr: 2.857 ± 0.565
1.948PheVal: 1.948 ± 0.335
0.13PheTrp: 0.13 ± 0.113
1.039PheTyr: 1.039 ± 0.393
0.0PheXaa: 0.0 ± 0.0
Gly
3.506GlyAla: 3.506 ± 0.932
0.39GlyCys: 0.39 ± 0.204
3.506GlyAsp: 3.506 ± 0.769
3.506GlyGlu: 3.506 ± 0.47
1.299GlyPhe: 1.299 ± 0.445
2.078GlyGly: 2.078 ± 0.432
1.039GlyHis: 1.039 ± 0.471
4.026GlyIle: 4.026 ± 0.477
2.208GlyLys: 2.208 ± 0.551
3.766GlyLeu: 3.766 ± 0.662
1.039GlyMet: 1.039 ± 0.343
2.468GlyAsn: 2.468 ± 0.556
1.558GlyPro: 1.558 ± 0.317
1.688GlyGln: 1.688 ± 0.204
2.857GlyArg: 2.857 ± 0.338
3.506GlySer: 3.506 ± 0.518
4.026GlyThr: 4.026 ± 0.76
3.377GlyVal: 3.377 ± 0.557
0.13GlyTrp: 0.13 ± 0.113
2.727GlyTyr: 2.727 ± 0.473
0.0GlyXaa: 0.0 ± 0.0
His
2.338HisAla: 2.338 ± 0.354
0.13HisCys: 0.13 ± 0.113
0.779HisAsp: 0.779 ± 0.349
2.078HisGlu: 2.078 ± 0.447
0.909HisPhe: 0.909 ± 0.222
0.779HisGly: 0.779 ± 0.302
0.779HisHis: 0.779 ± 0.426
1.688HisIle: 1.688 ± 0.366
1.948HisLys: 1.948 ± 0.573
2.338HisLeu: 2.338 ± 0.475
0.26HisMet: 0.26 ± 0.204
1.169HisAsn: 1.169 ± 0.28
0.909HisPro: 0.909 ± 0.348
1.169HisGln: 1.169 ± 0.399
1.429HisArg: 1.429 ± 0.251
2.078HisSer: 2.078 ± 0.702
1.818HisThr: 1.818 ± 0.48
2.078HisVal: 2.078 ± 0.504
0.13HisTrp: 0.13 ± 0.112
0.779HisTyr: 0.779 ± 0.428
0.0HisXaa: 0.0 ± 0.0
Ile
4.935IleAla: 4.935 ± 0.704
0.649IleCys: 0.649 ± 0.2
4.545IleAsp: 4.545 ± 0.801
2.857IleGlu: 2.857 ± 0.56
2.338IlePhe: 2.338 ± 0.319
3.117IleGly: 3.117 ± 0.709
1.558IleHis: 1.558 ± 0.365
3.377IleIle: 3.377 ± 0.74
3.896IleLys: 3.896 ± 0.862
4.935IleLeu: 4.935 ± 0.605
2.468IleMet: 2.468 ± 0.523
4.805IleAsn: 4.805 ± 0.931
3.506IlePro: 3.506 ± 0.664
1.948IleGln: 1.948 ± 0.362
4.286IleArg: 4.286 ± 0.916
5.974IleSer: 5.974 ± 0.542
5.455IleThr: 5.455 ± 0.913
4.286IleVal: 4.286 ± 0.831
0.26IleTrp: 0.26 ± 0.224
2.208IleTyr: 2.208 ± 0.342
0.0IleXaa: 0.0 ± 0.0
Lys
2.208LysAla: 2.208 ± 0.473
0.649LysCys: 0.649 ± 0.396
1.299LysAsp: 1.299 ± 0.399
2.727LysGlu: 2.727 ± 0.99
1.818LysPhe: 1.818 ± 0.571
2.338LysGly: 2.338 ± 0.401
1.558LysHis: 1.558 ± 0.594
2.597LysIle: 2.597 ± 0.523
2.727LysLys: 2.727 ± 0.763
4.286LysLeu: 4.286 ± 0.465
1.558LysMet: 1.558 ± 0.393
2.468LysAsn: 2.468 ± 0.567
2.338LysPro: 2.338 ± 0.936
2.468LysGln: 2.468 ± 0.805
2.597LysArg: 2.597 ± 0.499
2.338LysSer: 2.338 ± 0.61
2.857LysThr: 2.857 ± 0.72
2.338LysVal: 2.338 ± 0.365
0.779LysTrp: 0.779 ± 0.259
2.468LysTyr: 2.468 ± 0.407
0.0LysXaa: 0.0 ± 0.0
Leu
5.584LeuAla: 5.584 ± 0.744
1.169LeuCys: 1.169 ± 0.354
5.325LeuAsp: 5.325 ± 1.154
4.675LeuGlu: 4.675 ± 0.749
4.805LeuPhe: 4.805 ± 0.783
4.026LeuGly: 4.026 ± 0.909
3.117LeuHis: 3.117 ± 0.767
4.805LeuIle: 4.805 ± 0.948
3.377LeuLys: 3.377 ± 0.631
7.143LeuLeu: 7.143 ± 0.798
2.727LeuMet: 2.727 ± 0.358
3.377LeuAsn: 3.377 ± 0.603
3.506LeuPro: 3.506 ± 0.568
3.117LeuGln: 3.117 ± 0.534
6.104LeuArg: 6.104 ± 1.121
8.961LeuSer: 8.961 ± 0.421
5.974LeuThr: 5.974 ± 0.783
5.844LeuVal: 5.844 ± 0.426
0.39LeuTrp: 0.39 ± 0.24
3.506LeuTyr: 3.506 ± 0.764
0.0LeuXaa: 0.0 ± 0.0
Met
0.909MetAla: 0.909 ± 0.283
0.0MetCys: 0.0 ± 0.0
1.558MetAsp: 1.558 ± 0.347
1.558MetGlu: 1.558 ± 0.459
1.299MetPhe: 1.299 ± 0.333
0.519MetGly: 0.519 ± 0.237
0.909MetHis: 0.909 ± 0.247
1.688MetIle: 1.688 ± 0.343
0.779MetLys: 0.779 ± 0.344
2.468MetLeu: 2.468 ± 0.395
1.299MetMet: 1.299 ± 0.379
1.948MetAsn: 1.948 ± 0.515
1.299MetPro: 1.299 ± 0.418
0.779MetGln: 0.779 ± 0.272
2.078MetArg: 2.078 ± 0.492
2.468MetSer: 2.468 ± 0.444
2.857MetThr: 2.857 ± 0.468
1.299MetVal: 1.299 ± 0.503
0.13MetTrp: 0.13 ± 0.112
1.169MetTyr: 1.169 ± 0.312
0.0MetXaa: 0.0 ± 0.0
Asn
4.026AsnAla: 4.026 ± 0.682
0.39AsnCys: 0.39 ± 0.211
3.636AsnAsp: 3.636 ± 0.605
3.506AsnGlu: 3.506 ± 1.064
1.429AsnPhe: 1.429 ± 0.434
3.247AsnGly: 3.247 ± 0.566
1.818AsnHis: 1.818 ± 0.495
3.896AsnIle: 3.896 ± 0.693
2.208AsnLys: 2.208 ± 0.598
3.117AsnLeu: 3.117 ± 0.602
1.558AsnMet: 1.558 ± 0.472
3.636AsnAsn: 3.636 ± 0.482
2.078AsnPro: 2.078 ± 0.424
2.208AsnGln: 2.208 ± 0.567
2.857AsnArg: 2.857 ± 0.547
4.156AsnSer: 4.156 ± 1.191
4.156AsnThr: 4.156 ± 0.404
4.675AsnVal: 4.675 ± 0.912
0.39AsnTrp: 0.39 ± 0.221
2.078AsnTyr: 2.078 ± 0.464
0.0AsnXaa: 0.0 ± 0.0
Pro
3.247ProAla: 3.247 ± 0.676
0.13ProCys: 0.13 ± 0.13
2.078ProAsp: 2.078 ± 0.777
2.468ProGlu: 2.468 ± 0.704
1.688ProPhe: 1.688 ± 0.619
1.429ProGly: 1.429 ± 0.337
1.169ProHis: 1.169 ± 0.415
3.247ProIle: 3.247 ± 0.791
1.688ProLys: 1.688 ± 0.406
3.766ProLeu: 3.766 ± 0.539
0.649ProMet: 0.649 ± 0.275
2.208ProAsn: 2.208 ± 0.825
1.299ProPro: 1.299 ± 0.335
1.429ProGln: 1.429 ± 0.422
2.857ProArg: 2.857 ± 0.328
4.156ProSer: 4.156 ± 0.476
3.766ProThr: 3.766 ± 0.649
3.247ProVal: 3.247 ± 0.402
0.26ProTrp: 0.26 ± 0.176
1.299ProTyr: 1.299 ± 0.212
0.0ProXaa: 0.0 ± 0.0
Gln
3.117GlnAla: 3.117 ± 0.533
0.519GlnCys: 0.519 ± 0.173
1.688GlnAsp: 1.688 ± 0.383
1.558GlnGlu: 1.558 ± 0.313
2.078GlnPhe: 2.078 ± 0.506
1.948GlnGly: 1.948 ± 0.527
1.039GlnHis: 1.039 ± 0.395
3.766GlnIle: 3.766 ± 0.57
1.299GlnLys: 1.299 ± 0.229
3.766GlnLeu: 3.766 ± 0.658
0.779GlnMet: 0.779 ± 0.283
1.688GlnAsn: 1.688 ± 0.438
1.039GlnPro: 1.039 ± 0.338
2.078GlnGln: 2.078 ± 0.605
2.727GlnArg: 2.727 ± 0.506
3.117GlnSer: 3.117 ± 0.414
2.987GlnThr: 2.987 ± 0.525
1.558GlnVal: 1.558 ± 0.513
0.26GlnTrp: 0.26 ± 0.135
1.169GlnTyr: 1.169 ± 0.375
0.0GlnXaa: 0.0 ± 0.0
Arg
5.325ArgAla: 5.325 ± 0.785
0.519ArgCys: 0.519 ± 0.197
2.987ArgAsp: 2.987 ± 0.528
3.117ArgGlu: 3.117 ± 0.438
2.468ArgPhe: 2.468 ± 0.487
2.338ArgGly: 2.338 ± 0.66
1.039ArgHis: 1.039 ± 0.345
4.026ArgIle: 4.026 ± 0.676
1.818ArgLys: 1.818 ± 0.438
7.013ArgLeu: 7.013 ± 0.614
1.299ArgMet: 1.299 ± 0.388
2.987ArgAsn: 2.987 ± 0.833
2.727ArgPro: 2.727 ± 0.598
2.597ArgGln: 2.597 ± 0.811
3.247ArgArg: 3.247 ± 0.504
4.026ArgSer: 4.026 ± 0.745
4.805ArgThr: 4.805 ± 0.492
3.377ArgVal: 3.377 ± 0.836
0.519ArgTrp: 0.519 ± 0.33
2.208ArgTyr: 2.208 ± 0.418
0.0ArgXaa: 0.0 ± 0.0
Ser
5.195SerAla: 5.195 ± 0.635
0.519SerCys: 0.519 ± 0.16
4.935SerAsp: 4.935 ± 0.519
4.675SerGlu: 4.675 ± 0.405
2.727SerPhe: 2.727 ± 0.579
3.896SerGly: 3.896 ± 0.779
1.688SerHis: 1.688 ± 0.449
4.805SerIle: 4.805 ± 0.466
3.377SerLys: 3.377 ± 0.782
6.234SerLeu: 6.234 ± 1.281
2.338SerMet: 2.338 ± 0.499
4.545SerAsn: 4.545 ± 0.464
3.766SerPro: 3.766 ± 0.408
2.727SerGln: 2.727 ± 0.638
4.416SerArg: 4.416 ± 0.718
5.455SerSer: 5.455 ± 0.572
6.364SerThr: 6.364 ± 0.993
5.714SerVal: 5.714 ± 1.091
1.039SerTrp: 1.039 ± 0.321
4.286SerTyr: 4.286 ± 0.621
0.0SerXaa: 0.0 ± 0.0
Thr
5.714ThrAla: 5.714 ± 0.574
0.649ThrCys: 0.649 ± 0.266
4.286ThrAsp: 4.286 ± 0.831
3.377ThrGlu: 3.377 ± 0.592
3.247ThrPhe: 3.247 ± 0.681
3.117ThrGly: 3.117 ± 0.524
2.338ThrHis: 2.338 ± 0.674
5.325ThrIle: 5.325 ± 1.01
3.377ThrLys: 3.377 ± 0.677
6.753ThrLeu: 6.753 ± 1.065
1.558ThrMet: 1.558 ± 0.624
3.636ThrAsn: 3.636 ± 0.863
3.896ThrPro: 3.896 ± 0.823
2.597ThrGln: 2.597 ± 0.548
4.286ThrArg: 4.286 ± 0.589
5.455ThrSer: 5.455 ± 0.716
6.883ThrThr: 6.883 ± 0.749
4.286ThrVal: 4.286 ± 0.472
0.909ThrTrp: 0.909 ± 0.291
4.286ThrTyr: 4.286 ± 0.743
0.0ThrXaa: 0.0 ± 0.0
Val
5.714ValAla: 5.714 ± 0.943
0.13ValCys: 0.13 ± 0.162
2.987ValAsp: 2.987 ± 0.735
3.247ValGlu: 3.247 ± 0.384
2.857ValPhe: 2.857 ± 0.709
3.766ValGly: 3.766 ± 0.579
1.039ValHis: 1.039 ± 0.297
4.675ValIle: 4.675 ± 0.77
3.636ValLys: 3.636 ± 0.588
4.675ValLeu: 4.675 ± 0.6
1.688ValMet: 1.688 ± 0.345
4.026ValAsn: 4.026 ± 0.703
2.857ValPro: 2.857 ± 0.628
2.338ValGln: 2.338 ± 0.526
4.026ValArg: 4.026 ± 0.527
6.364ValSer: 6.364 ± 1.135
4.286ValThr: 4.286 ± 0.402
3.636ValVal: 3.636 ± 1.076
0.649ValTrp: 0.649 ± 0.26
3.247ValTyr: 3.247 ± 0.706
0.0ValXaa: 0.0 ± 0.0
Trp
0.26TrpAla: 0.26 ± 0.16
0.0TrpCys: 0.0 ± 0.0
0.39TrpAsp: 0.39 ± 0.193
0.39TrpGlu: 0.39 ± 0.19
0.26TrpPhe: 0.26 ± 0.177
0.13TrpGly: 0.13 ± 0.113
0.39TrpHis: 0.39 ± 0.336
0.13TrpIle: 0.13 ± 0.13
0.39TrpLys: 0.39 ± 0.283
0.779TrpLeu: 0.779 ± 0.259
0.519TrpMet: 0.519 ± 0.265
0.39TrpAsn: 0.39 ± 0.157
0.39TrpPro: 0.39 ± 0.145
0.39TrpGln: 0.39 ± 0.215
0.39TrpArg: 0.39 ± 0.222
0.909TrpSer: 0.909 ± 0.276
0.39TrpThr: 0.39 ± 0.247
0.519TrpVal: 0.519 ± 0.247
0.13TrpTrp: 0.13 ± 0.101
0.519TrpTyr: 0.519 ± 0.246
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.896TyrAla: 3.896 ± 0.539
0.13TyrCys: 0.13 ± 0.112
2.597TyrAsp: 2.597 ± 0.737
2.727TyrGlu: 2.727 ± 0.449
1.429TyrPhe: 1.429 ± 0.29
3.117TyrGly: 3.117 ± 0.726
0.649TyrHis: 0.649 ± 0.246
2.857TyrIle: 2.857 ± 0.523
1.688TyrLys: 1.688 ± 0.432
2.987TyrLeu: 2.987 ± 0.429
1.039TyrMet: 1.039 ± 0.402
2.857TyrAsn: 2.857 ± 0.764
2.597TyrPro: 2.597 ± 0.501
1.429TyrGln: 1.429 ± 0.225
2.208TyrArg: 2.208 ± 0.554
2.468TyrSer: 2.468 ± 0.411
3.377TyrThr: 3.377 ± 0.664
2.987TyrVal: 2.987 ± 0.458
0.39TyrTrp: 0.39 ± 0.199
1.818TyrTyr: 1.818 ± 0.58
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (7701 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski