Amino acid dipepetide frequency for Aquareovirus C (isolate Golden shiner/USA/GSRV/1977) (AQRV-C)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.59AlaAla: 14.59 ± 1.61
1.052AlaCys: 1.052 ± 0.695
4.075AlaAsp: 4.075 ± 0.602
2.366AlaGlu: 2.366 ± 0.352
4.863AlaPhe: 4.863 ± 0.955
6.309AlaGly: 6.309 ± 0.819
3.155AlaHis: 3.155 ± 0.736
6.703AlaIle: 6.703 ± 1.314
1.183AlaLys: 1.183 ± 0.564
11.435AlaLeu: 11.435 ± 1.011
3.286AlaMet: 3.286 ± 0.812
4.6AlaAsn: 4.6 ± 0.567
6.835AlaPro: 6.835 ± 1.176
3.68AlaGln: 3.68 ± 0.916
5.783AlaArg: 5.783 ± 0.636
8.675AlaSer: 8.675 ± 0.965
8.149AlaThr: 8.149 ± 1.651
6.835AlaVal: 6.835 ± 1.137
0.92AlaTrp: 0.92 ± 0.223
2.892AlaTyr: 2.892 ± 0.547
0.0AlaXaa: 0.0 ± 0.0
Cys
1.446CysAla: 1.446 ± 0.381
0.263CysCys: 0.263 ± 0.335
1.183CysAsp: 1.183 ± 0.441
0.263CysGlu: 0.263 ± 0.196
0.131CysPhe: 0.131 ± 0.111
0.92CysGly: 0.92 ± 0.403
0.263CysHis: 0.263 ± 0.205
0.789CysIle: 0.789 ± 0.325
0.131CysLys: 0.131 ± 0.115
1.84CysLeu: 1.84 ± 0.818
0.526CysMet: 0.526 ± 0.376
0.526CysAsn: 0.526 ± 0.269
0.526CysPro: 0.526 ± 0.318
0.526CysGln: 0.526 ± 0.248
0.394CysArg: 0.394 ± 0.203
0.263CysSer: 0.263 ± 0.23
0.657CysThr: 0.657 ± 0.346
0.789CysVal: 0.789 ± 0.349
0.131CysTrp: 0.131 ± 0.132
0.657CysTyr: 0.657 ± 0.316
0.0CysXaa: 0.0 ± 0.0
Asp
5.258AspAla: 5.258 ± 0.858
0.263AspCys: 0.263 ± 0.218
3.417AspAsp: 3.417 ± 0.666
1.84AspGlu: 1.84 ± 0.635
1.446AspPhe: 1.446 ± 0.569
3.68AspGly: 3.68 ± 0.738
1.314AspHis: 1.314 ± 0.444
3.417AspIle: 3.417 ± 0.564
0.92AspLys: 0.92 ± 0.432
5.521AspLeu: 5.521 ± 0.852
1.446AspMet: 1.446 ± 0.513
1.183AspAsn: 1.183 ± 0.329
5.652AspPro: 5.652 ± 0.724
1.709AspGln: 1.709 ± 0.422
3.023AspArg: 3.023 ± 0.962
4.469AspSer: 4.469 ± 0.55
3.812AspThr: 3.812 ± 0.597
4.995AspVal: 4.995 ± 0.597
1.183AspTrp: 1.183 ± 0.324
2.103AspTyr: 2.103 ± 0.383
0.0AspXaa: 0.0 ± 0.0
Glu
2.76GluAla: 2.76 ± 0.691
0.394GluCys: 0.394 ± 0.249
1.052GluAsp: 1.052 ± 0.318
0.526GluGlu: 0.526 ± 0.214
1.314GluPhe: 1.314 ± 0.425
1.052GluGly: 1.052 ± 0.309
0.789GluHis: 0.789 ± 0.347
1.052GluIle: 1.052 ± 0.411
0.526GluLys: 0.526 ± 0.232
3.943GluLeu: 3.943 ± 1.014
0.263GluMet: 0.263 ± 0.176
0.789GluAsn: 0.789 ± 0.226
1.183GluPro: 1.183 ± 0.258
1.314GluGln: 1.314 ± 0.52
2.366GluArg: 2.366 ± 0.523
1.577GluSer: 1.577 ± 0.352
1.972GluThr: 1.972 ± 0.584
2.629GluVal: 2.629 ± 0.449
0.657GluTrp: 0.657 ± 0.232
1.709GluTyr: 1.709 ± 0.632
0.0GluXaa: 0.0 ± 0.0
Phe
2.497PheAla: 2.497 ± 0.72
0.657PheCys: 0.657 ± 0.258
2.76PheAsp: 2.76 ± 0.705
1.577PheGlu: 1.577 ± 0.46
0.526PhePhe: 0.526 ± 0.181
2.366PheGly: 2.366 ± 0.604
0.131PheHis: 0.131 ± 0.123
1.314PheIle: 1.314 ± 0.332
0.657PheLys: 0.657 ± 0.23
2.892PheLeu: 2.892 ± 0.792
1.183PheMet: 1.183 ± 0.432
2.234PheAsn: 2.234 ± 0.455
1.972PhePro: 1.972 ± 0.771
0.394PheGln: 0.394 ± 0.217
1.577PheArg: 1.577 ± 0.438
3.023PheSer: 3.023 ± 0.579
3.286PheThr: 3.286 ± 1.016
2.629PheVal: 2.629 ± 0.52
0.526PheTrp: 0.526 ± 0.284
1.446PheTyr: 1.446 ± 0.341
0.0PheXaa: 0.0 ± 0.0
Gly
3.812GlyAla: 3.812 ± 0.631
0.789GlyCys: 0.789 ± 0.292
3.155GlyAsp: 3.155 ± 0.545
1.183GlyGlu: 1.183 ± 0.344
2.103GlyPhe: 2.103 ± 0.461
2.76GlyGly: 2.76 ± 0.842
0.92GlyHis: 0.92 ± 0.411
3.023GlyIle: 3.023 ± 0.422
1.709GlyLys: 1.709 ± 0.565
4.6GlyLeu: 4.6 ± 0.842
1.314GlyMet: 1.314 ± 0.395
2.629GlyAsn: 2.629 ± 0.456
3.549GlyPro: 3.549 ± 0.386
2.366GlyGln: 2.366 ± 0.883
3.155GlyArg: 3.155 ± 0.75
3.286GlySer: 3.286 ± 0.624
3.155GlyThr: 3.155 ± 0.834
4.6GlyVal: 4.6 ± 0.742
0.657GlyTrp: 0.657 ± 0.336
1.709GlyTyr: 1.709 ± 0.343
0.0GlyXaa: 0.0 ± 0.0
His
3.943HisAla: 3.943 ± 1.257
0.131HisCys: 0.131 ± 0.155
1.314HisAsp: 1.314 ± 0.685
0.789HisGlu: 0.789 ± 0.305
0.657HisPhe: 0.657 ± 0.26
0.657HisGly: 0.657 ± 0.324
0.789HisHis: 0.789 ± 0.422
1.709HisIle: 1.709 ± 0.277
0.394HisLys: 0.394 ± 0.214
3.943HisLeu: 3.943 ± 0.766
0.657HisMet: 0.657 ± 0.258
0.789HisAsn: 0.789 ± 0.35
1.709HisPro: 1.709 ± 0.391
1.183HisGln: 1.183 ± 0.347
1.052HisArg: 1.052 ± 0.43
1.972HisSer: 1.972 ± 0.65
1.052HisThr: 1.052 ± 0.415
1.84HisVal: 1.84 ± 0.411
0.526HisTrp: 0.526 ± 0.253
0.789HisTyr: 0.789 ± 0.478
0.0HisXaa: 0.0 ± 0.0
Ile
4.863IleAla: 4.863 ± 0.872
0.526IleCys: 0.526 ± 0.237
4.206IleAsp: 4.206 ± 0.507
1.446IleGlu: 1.446 ± 0.332
0.92IlePhe: 0.92 ± 0.431
2.366IleGly: 2.366 ± 0.522
1.446IleHis: 1.446 ± 0.297
1.183IleIle: 1.183 ± 0.276
0.789IleLys: 0.789 ± 0.284
3.68IleLeu: 3.68 ± 0.571
0.789IleMet: 0.789 ± 0.249
2.234IleAsn: 2.234 ± 0.471
5.521IlePro: 5.521 ± 0.91
2.103IleGln: 2.103 ± 0.47
3.155IleArg: 3.155 ± 0.579
3.68IleSer: 3.68 ± 0.585
4.732IleThr: 4.732 ± 0.762
4.206IleVal: 4.206 ± 0.662
0.789IleTrp: 0.789 ± 0.462
1.183IleTyr: 1.183 ± 0.368
0.0IleXaa: 0.0 ± 0.0
Lys
1.972LysAla: 1.972 ± 0.355
0.394LysCys: 0.394 ± 0.241
1.314LysAsp: 1.314 ± 0.372
0.394LysGlu: 0.394 ± 0.162
0.657LysPhe: 0.657 ± 0.337
1.052LysGly: 1.052 ± 0.406
0.526LysHis: 0.526 ± 0.142
0.92LysIle: 0.92 ± 0.425
0.263LysLys: 0.263 ± 0.16
2.103LysLeu: 2.103 ± 0.748
0.131LysMet: 0.131 ± 0.12
0.263LysAsn: 0.263 ± 0.179
2.234LysPro: 2.234 ± 0.482
0.263LysGln: 0.263 ± 0.18
0.789LysArg: 0.789 ± 0.309
1.577LysSer: 1.577 ± 0.544
1.183LysThr: 1.183 ± 0.617
1.709LysVal: 1.709 ± 0.339
0.526LysTrp: 0.526 ± 0.25
0.92LysTyr: 0.92 ± 0.323
0.0LysXaa: 0.0 ± 0.0
Leu
9.201LeuAla: 9.201 ± 0.941
1.577LeuCys: 1.577 ± 0.478
7.492LeuAsp: 7.492 ± 0.946
3.023LeuGlu: 3.023 ± 0.732
2.892LeuPhe: 2.892 ± 0.361
3.943LeuGly: 3.943 ± 0.917
2.497LeuHis: 2.497 ± 0.505
4.863LeuIle: 4.863 ± 0.556
2.366LeuLys: 2.366 ± 0.673
12.093LeuLeu: 12.093 ± 1.464
2.366LeuMet: 2.366 ± 0.436
4.469LeuAsn: 4.469 ± 1.107
8.281LeuPro: 8.281 ± 0.883
4.206LeuGln: 4.206 ± 0.642
7.624LeuArg: 7.624 ± 0.916
8.149LeuSer: 8.149 ± 0.606
8.807LeuThr: 8.807 ± 1.257
5.521LeuVal: 5.521 ± 0.814
0.92LeuTrp: 0.92 ± 0.575
2.497LeuTyr: 2.497 ± 0.717
0.0LeuXaa: 0.0 ± 0.0
Met
2.892MetAla: 2.892 ± 0.537
0.131MetCys: 0.131 ± 0.125
0.657MetAsp: 0.657 ± 0.226
0.394MetGlu: 0.394 ± 0.22
1.314MetPhe: 1.314 ± 0.373
1.052MetGly: 1.052 ± 0.43
0.92MetHis: 0.92 ± 0.496
0.92MetIle: 0.92 ± 0.365
0.394MetLys: 0.394 ± 0.22
1.709MetLeu: 1.709 ± 0.425
0.657MetMet: 0.657 ± 0.361
0.92MetAsn: 0.92 ± 0.339
1.84MetPro: 1.84 ± 0.426
0.657MetGln: 0.657 ± 0.262
1.577MetArg: 1.577 ± 0.51
2.497MetSer: 2.497 ± 0.424
2.497MetThr: 2.497 ± 0.66
1.577MetVal: 1.577 ± 0.375
0.789MetTrp: 0.789 ± 0.339
0.92MetTyr: 0.92 ± 0.325
0.0MetXaa: 0.0 ± 0.0
Asn
4.469AsnAla: 4.469 ± 0.992
0.131AsnCys: 0.131 ± 0.173
2.103AsnAsp: 2.103 ± 0.723
1.183AsnGlu: 1.183 ± 0.524
0.92AsnPhe: 0.92 ± 0.306
2.76AsnGly: 2.76 ± 0.382
0.92AsnHis: 0.92 ± 0.312
1.052AsnIle: 1.052 ± 0.394
0.657AsnLys: 0.657 ± 0.329
3.812AsnLeu: 3.812 ± 0.694
0.789AsnMet: 0.789 ± 0.269
1.314AsnAsn: 1.314 ± 0.609
3.549AsnPro: 3.549 ± 0.986
1.972AsnGln: 1.972 ± 0.372
1.577AsnArg: 1.577 ± 0.333
1.577AsnSer: 1.577 ± 0.381
2.103AsnThr: 2.103 ± 0.447
4.075AsnVal: 4.075 ± 0.718
1.314AsnTrp: 1.314 ± 0.496
1.183AsnTyr: 1.183 ± 0.519
0.0AsnXaa: 0.0 ± 0.0
Pro
8.807ProAla: 8.807 ± 0.989
0.526ProCys: 0.526 ± 0.214
3.417ProAsp: 3.417 ± 0.572
1.84ProGlu: 1.84 ± 0.47
2.629ProPhe: 2.629 ± 0.659
3.68ProGly: 3.68 ± 0.547
1.84ProHis: 1.84 ± 0.502
4.469ProIle: 4.469 ± 0.66
1.183ProLys: 1.183 ± 0.602
8.281ProLeu: 8.281 ± 0.679
1.577ProMet: 1.577 ± 0.603
2.366ProAsn: 2.366 ± 0.731
7.755ProPro: 7.755 ± 0.981
2.629ProGln: 2.629 ± 0.648
3.68ProArg: 3.68 ± 0.482
8.149ProSer: 8.149 ± 1.029
8.807ProThr: 8.807 ± 1.011
5.521ProVal: 5.521 ± 1.067
0.92ProTrp: 0.92 ± 0.325
1.577ProTyr: 1.577 ± 0.65
0.0ProXaa: 0.0 ± 0.0
Gln
4.075GlnAla: 4.075 ± 0.704
0.263GlnCys: 0.263 ± 0.148
1.314GlnAsp: 1.314 ± 0.423
0.92GlnGlu: 0.92 ± 0.433
1.314GlnPhe: 1.314 ± 0.526
1.446GlnGly: 1.446 ± 0.626
1.709GlnHis: 1.709 ± 0.495
2.366GlnIle: 2.366 ± 0.511
0.263GlnLys: 0.263 ± 0.271
3.549GlnLeu: 3.549 ± 0.594
0.92GlnMet: 0.92 ± 0.272
0.263GlnAsn: 0.263 ± 0.148
2.497GlnPro: 2.497 ± 0.556
2.234GlnGln: 2.234 ± 0.53
2.234GlnArg: 2.234 ± 0.342
2.497GlnSer: 2.497 ± 0.46
2.76GlnThr: 2.76 ± 0.465
3.155GlnVal: 3.155 ± 0.557
0.657GlnTrp: 0.657 ± 0.266
1.709GlnTyr: 1.709 ± 0.534
0.0GlnXaa: 0.0 ± 0.0
Arg
6.441ArgAla: 6.441 ± 0.693
1.446ArgCys: 1.446 ± 0.516
3.68ArgAsp: 3.68 ± 0.813
2.103ArgGlu: 2.103 ± 0.495
2.103ArgPhe: 2.103 ± 0.296
1.972ArgGly: 1.972 ± 0.489
1.577ArgHis: 1.577 ± 0.6
2.629ArgIle: 2.629 ± 0.768
0.394ArgLys: 0.394 ± 0.202
5.915ArgLeu: 5.915 ± 1.056
1.052ArgMet: 1.052 ± 0.235
1.972ArgAsn: 1.972 ± 0.614
3.68ArgPro: 3.68 ± 0.305
1.972ArgGln: 1.972 ± 0.404
3.68ArgArg: 3.68 ± 0.625
5.258ArgSer: 5.258 ± 0.797
2.892ArgThr: 2.892 ± 0.577
5.389ArgVal: 5.389 ± 0.911
0.394ArgTrp: 0.394 ± 0.18
1.446ArgTyr: 1.446 ± 0.284
0.0ArgXaa: 0.0 ± 0.0
Ser
9.069SerAla: 9.069 ± 1.315
0.789SerCys: 0.789 ± 0.393
6.441SerAsp: 6.441 ± 1.036
2.366SerGlu: 2.366 ± 0.728
2.76SerPhe: 2.76 ± 0.607
3.812SerGly: 3.812 ± 0.876
1.972SerHis: 1.972 ± 0.62
3.943SerIle: 3.943 ± 0.823
1.709SerLys: 1.709 ± 0.531
8.807SerLeu: 8.807 ± 1.302
1.314SerMet: 1.314 ± 0.319
2.366SerAsn: 2.366 ± 0.625
4.863SerPro: 4.863 ± 0.623
1.84SerGln: 1.84 ± 0.388
4.075SerArg: 4.075 ± 0.711
6.703SerSer: 6.703 ± 0.86
8.938SerThr: 8.938 ± 0.939
6.046SerVal: 6.046 ± 0.754
0.92SerTrp: 0.92 ± 0.273
1.709SerTyr: 1.709 ± 0.29
0.0SerXaa: 0.0 ± 0.0
Thr
9.858ThrAla: 9.858 ± 1.786
1.446ThrCys: 1.446 ± 0.539
3.417ThrAsp: 3.417 ± 0.823
1.577ThrGlu: 1.577 ± 0.423
3.155ThrPhe: 3.155 ± 0.372
4.863ThrGly: 4.863 ± 0.872
1.84ThrHis: 1.84 ± 0.512
4.995ThrIle: 4.995 ± 0.599
1.84ThrLys: 1.84 ± 0.426
8.018ThrLeu: 8.018 ± 0.936
2.629ThrMet: 2.629 ± 0.573
3.023ThrAsn: 3.023 ± 0.919
6.046ThrPro: 6.046 ± 1.256
2.234ThrGln: 2.234 ± 0.407
3.417ThrArg: 3.417 ± 0.646
8.544ThrSer: 8.544 ± 1.314
6.309ThrThr: 6.309 ± 1.384
4.469ThrVal: 4.469 ± 0.645
0.789ThrTrp: 0.789 ± 0.262
2.892ThrTyr: 2.892 ± 0.515
0.0ThrXaa: 0.0 ± 0.0
Val
7.229ValAla: 7.229 ± 0.934
1.052ValCys: 1.052 ± 0.433
3.155ValAsp: 3.155 ± 0.655
3.155ValGlu: 3.155 ± 0.632
2.103ValPhe: 2.103 ± 0.633
3.155ValGly: 3.155 ± 0.914
1.709ValHis: 1.709 ± 0.285
2.497ValIle: 2.497 ± 0.381
1.972ValLys: 1.972 ± 0.422
7.229ValLeu: 7.229 ± 1.013
2.497ValMet: 2.497 ± 0.456
3.549ValAsn: 3.549 ± 0.829
7.492ValPro: 7.492 ± 0.822
3.417ValGln: 3.417 ± 0.773
3.68ValArg: 3.68 ± 0.547
5.389ValSer: 5.389 ± 0.821
6.572ValThr: 6.572 ± 0.609
5.126ValVal: 5.126 ± 0.709
1.052ValTrp: 1.052 ± 0.331
2.234ValTyr: 2.234 ± 0.462
0.0ValXaa: 0.0 ± 0.0
Trp
0.789TrpAla: 0.789 ± 0.362
0.0TrpCys: 0.0 ± 0.0
0.131TrpAsp: 0.131 ± 0.125
0.131TrpGlu: 0.131 ± 0.111
0.92TrpPhe: 0.92 ± 0.278
0.263TrpGly: 0.263 ± 0.16
0.526TrpHis: 0.526 ± 0.235
0.657TrpIle: 0.657 ± 0.351
0.789TrpLys: 0.789 ± 0.357
1.446TrpLeu: 1.446 ± 0.34
0.526TrpMet: 0.526 ± 0.33
0.394TrpAsn: 0.394 ± 0.186
1.577TrpPro: 1.577 ± 0.538
0.657TrpGln: 0.657 ± 0.311
1.052TrpArg: 1.052 ± 0.474
1.446TrpSer: 1.446 ± 0.404
1.84TrpThr: 1.84 ± 0.511
0.657TrpVal: 0.657 ± 0.252
0.263TrpTrp: 0.263 ± 0.222
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.417TyrAla: 3.417 ± 0.662
0.394TyrCys: 0.394 ± 0.224
2.366TyrAsp: 2.366 ± 0.646
0.92TyrGlu: 0.92 ± 0.383
0.92TyrPhe: 0.92 ± 0.433
2.366TyrGly: 2.366 ± 0.428
1.052TyrHis: 1.052 ± 0.384
1.314TyrIle: 1.314 ± 0.265
1.052TyrLys: 1.052 ± 0.451
1.972TyrLeu: 1.972 ± 0.753
0.263TyrMet: 0.263 ± 0.181
1.577TyrAsn: 1.577 ± 0.358
2.892TyrPro: 2.892 ± 0.473
0.789TyrGln: 0.789 ± 0.243
2.103TyrArg: 2.103 ± 0.522
1.709TyrSer: 1.709 ± 0.517
1.84TyrThr: 1.84 ± 0.479
2.497TyrVal: 2.497 ± 0.409
0.131TyrTrp: 0.131 ± 0.115
0.789TyrTyr: 0.789 ± 0.24
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (7609 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski