Amino acid dipepetide frequency for Fly associated circular virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.577AlaAla: 1.577 ± 1.12
0.0AlaCys: 0.0 ± 0.0
7.886AlaAsp: 7.886 ± 3.307
3.155AlaGlu: 3.155 ± 2.241
3.155AlaPhe: 3.155 ± 0.054
7.886AlaGly: 7.886 ± 1.012
0.0AlaHis: 0.0 ± 0.0
1.577AlaIle: 1.577 ± 1.175
1.577AlaLys: 1.577 ± 1.175
3.155AlaLeu: 3.155 ± 2.241
1.577AlaMet: 1.577 ± 0.78
3.155AlaAsn: 3.155 ± 2.349
1.577AlaPro: 1.577 ± 1.175
1.577AlaGln: 1.577 ± 1.175
4.732AlaArg: 4.732 ± 1.066
9.464AlaSer: 9.464 ± 4.753
4.732AlaThr: 4.732 ± 1.229
4.732AlaVal: 4.732 ± 1.229
0.0AlaTrp: 0.0 ± 0.0
4.732AlaTyr: 4.732 ± 1.066
0.0AlaXaa: 0.0 ± 0.0
Cys
1.577CysAla: 1.577 ± 1.12
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.577CysPhe: 1.577 ± 1.175
1.577CysGly: 1.577 ± 1.12
0.0CysHis: 0.0 ± 0.0
1.577CysIle: 1.577 ± 1.12
0.0CysLys: 0.0 ± 0.0
1.577CysLeu: 1.577 ± 1.12
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.577CysArg: 1.577 ± 1.175
0.0CysSer: 0.0 ± 0.0
1.577CysThr: 1.577 ± 1.12
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.577CysTyr: 1.577 ± 1.12
0.0CysXaa: 0.0 ± 0.0
Asp
4.732AspAla: 4.732 ± 1.066
0.0AspCys: 0.0 ± 0.0
12.618AspAsp: 12.618 ± 2.512
4.732AspGlu: 4.732 ± 1.066
4.732AspPhe: 4.732 ± 1.066
3.155AspGly: 3.155 ± 2.241
1.577AspHis: 1.577 ± 1.12
7.886AspIle: 7.886 ± 1.012
3.155AspLys: 3.155 ± 2.241
3.155AspLeu: 3.155 ± 0.054
0.0AspMet: 0.0 ± 0.0
3.155AspAsn: 3.155 ± 0.054
3.155AspPro: 3.155 ± 2.241
1.577AspGln: 1.577 ± 1.175
6.309AspArg: 6.309 ± 0.109
1.577AspSer: 1.577 ± 1.175
3.155AspThr: 3.155 ± 2.349
1.577AspVal: 1.577 ± 1.12
4.732AspTrp: 4.732 ± 1.066
3.155AspTyr: 3.155 ± 2.241
0.0AspXaa: 0.0 ± 0.0
Glu
1.577GluAla: 1.577 ± 1.175
0.0GluCys: 0.0 ± 0.0
1.577GluAsp: 1.577 ± 1.12
0.0GluGlu: 0.0 ± 0.0
1.577GluPhe: 1.577 ± 1.12
4.732GluGly: 4.732 ± 1.229
3.155GluHis: 3.155 ± 2.241
3.155GluIle: 3.155 ± 2.349
1.577GluLys: 1.577 ± 1.12
1.577GluLeu: 1.577 ± 1.12
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
0.0GluGln: 0.0 ± 0.0
4.732GluArg: 4.732 ± 1.066
0.0GluSer: 0.0 ± 0.0
6.309GluThr: 6.309 ± 0.109
1.577GluVal: 1.577 ± 1.12
1.577GluTrp: 1.577 ± 1.12
3.155GluTyr: 3.155 ± 2.241
0.0GluXaa: 0.0 ± 0.0
Phe
3.155PheAla: 3.155 ± 2.241
0.0PheCys: 0.0 ± 0.0
4.732PheAsp: 4.732 ± 3.361
0.0PheGlu: 0.0 ± 0.0
3.155PhePhe: 3.155 ± 0.054
4.732PheGly: 4.732 ± 3.361
1.577PheHis: 1.577 ± 1.12
1.577PheIle: 1.577 ± 1.175
1.577PheLys: 1.577 ± 1.12
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
3.155PheAsn: 3.155 ± 0.054
1.577PhePro: 1.577 ± 1.12
6.309PheGln: 6.309 ± 2.404
11.041PheArg: 11.041 ± 3.253
11.041PheSer: 11.041 ± 3.633
4.732PheThr: 4.732 ± 1.066
3.155PheVal: 3.155 ± 2.349
0.0PheTrp: 0.0 ± 0.0
1.577PheTyr: 1.577 ± 1.12
0.0PheXaa: 0.0 ± 0.0
Gly
4.732GlyAla: 4.732 ± 1.229
0.0GlyCys: 0.0 ± 0.0
4.732GlyAsp: 4.732 ± 1.229
4.732GlyGlu: 4.732 ± 1.066
3.155GlyPhe: 3.155 ± 2.241
9.464GlyGly: 9.464 ± 2.132
1.577GlyHis: 1.577 ± 1.175
3.155GlyIle: 3.155 ± 0.054
1.577GlyLys: 1.577 ± 1.12
6.309GlyLeu: 6.309 ± 0.109
0.0GlyMet: 0.0 ± 0.0
6.309GlyAsn: 6.309 ± 0.109
1.577GlyPro: 1.577 ± 1.175
4.732GlyGln: 4.732 ± 1.066
7.886GlyArg: 7.886 ± 3.307
7.886GlySer: 7.886 ± 1.283
6.309GlyThr: 6.309 ± 2.404
0.0GlyVal: 0.0 ± 0.0
3.155GlyTrp: 3.155 ± 2.241
3.155GlyTyr: 3.155 ± 2.349
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.577HisCys: 1.577 ± 1.12
1.577HisAsp: 1.577 ± 1.12
3.155HisGlu: 3.155 ± 2.349
1.577HisPhe: 1.577 ± 1.12
1.577HisGly: 1.577 ± 1.175
0.0HisHis: 0.0 ± 0.0
3.155HisIle: 3.155 ± 2.241
0.0HisLys: 0.0 ± 0.0
4.732HisLeu: 4.732 ± 3.361
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.577HisPro: 1.577 ± 1.12
3.155HisGln: 3.155 ± 2.241
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
3.155HisVal: 3.155 ± 0.054
0.0HisTrp: 0.0 ± 0.0
1.577HisTyr: 1.577 ± 1.175
0.0HisXaa: 0.0 ± 0.0
Ile
3.155IleAla: 3.155 ± 0.054
1.577IleCys: 1.577 ± 1.12
6.309IleAsp: 6.309 ± 0.109
3.155IleGlu: 3.155 ± 2.349
1.577IlePhe: 1.577 ± 1.175
3.155IleGly: 3.155 ± 0.054
1.577IleHis: 1.577 ± 1.12
3.155IleIle: 3.155 ± 0.054
1.577IleLys: 1.577 ± 1.12
0.0IleLeu: 0.0 ± 0.0
1.577IleMet: 1.577 ± 1.12
0.0IleAsn: 0.0 ± 0.0
0.0IlePro: 0.0 ± 0.0
4.732IleGln: 4.732 ± 1.229
6.309IleArg: 6.309 ± 2.404
4.732IleSer: 4.732 ± 1.229
0.0IleThr: 0.0 ± 0.0
6.309IleVal: 6.309 ± 0.109
1.577IleTrp: 1.577 ± 1.12
1.577IleTyr: 1.577 ± 1.175
0.0IleXaa: 0.0 ± 0.0
Lys
1.577LysAla: 1.577 ± 1.175
3.155LysCys: 3.155 ± 2.349
1.577LysAsp: 1.577 ± 1.12
0.0LysGlu: 0.0 ± 0.0
4.732LysPhe: 4.732 ± 3.361
0.0LysGly: 0.0 ± 0.0
1.577LysHis: 1.577 ± 1.175
0.0LysIle: 0.0 ± 0.0
3.155LysLys: 3.155 ± 2.241
0.0LysLeu: 0.0 ± 0.0
0.0LysMet: 0.0 ± 0.0
1.577LysAsn: 1.577 ± 1.12
0.0LysPro: 0.0 ± 0.0
0.0LysGln: 0.0 ± 0.0
0.0LysArg: 0.0 ± 0.0
4.732LysSer: 4.732 ± 1.066
1.577LysThr: 1.577 ± 1.12
3.155LysVal: 3.155 ± 0.054
1.577LysTrp: 1.577 ± 1.12
4.732LysTyr: 4.732 ± 3.361
0.0LysXaa: 0.0 ± 0.0
Leu
6.309LeuAla: 6.309 ± 2.404
0.0LeuCys: 0.0 ± 0.0
1.577LeuAsp: 1.577 ± 1.12
1.577LeuGlu: 1.577 ± 1.12
7.886LeuPhe: 7.886 ± 1.012
4.732LeuGly: 4.732 ± 3.361
3.155LeuHis: 3.155 ± 2.241
1.577LeuIle: 1.577 ± 1.12
0.0LeuLys: 0.0 ± 0.0
4.732LeuLeu: 4.732 ± 1.066
0.0LeuMet: 0.0 ± 0.0
0.0LeuAsn: 0.0 ± 0.0
1.577LeuPro: 1.577 ± 1.12
1.577LeuGln: 1.577 ± 1.175
6.309LeuArg: 6.309 ± 4.482
3.155LeuSer: 3.155 ± 0.054
0.0LeuThr: 0.0 ± 0.0
1.577LeuVal: 1.577 ± 1.12
1.577LeuTrp: 1.577 ± 1.12
3.155LeuTyr: 3.155 ± 0.054
0.0LeuXaa: 0.0 ± 0.0
Met
1.577MetAla: 1.577 ± 1.175
0.0MetCys: 0.0 ± 0.0
1.577MetAsp: 1.577 ± 1.175
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.577MetGly: 1.577 ± 1.175
0.0MetHis: 0.0 ± 0.0
1.577MetIle: 1.577 ± 1.175
0.0MetLys: 0.0 ± 0.0
1.577MetLeu: 1.577 ± 1.175
0.0MetMet: 0.0 ± 0.0
1.577MetAsn: 1.577 ± 1.12
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.577MetSer: 1.577 ± 1.12
3.155MetThr: 3.155 ± 2.349
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.577AsnAla: 1.577 ± 1.175
1.577AsnCys: 1.577 ± 1.12
3.155AsnAsp: 3.155 ± 0.054
1.577AsnGlu: 1.577 ± 1.12
0.0AsnPhe: 0.0 ± 0.0
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
1.577AsnIle: 1.577 ± 1.12
0.0AsnLys: 0.0 ± 0.0
4.732AsnLeu: 4.732 ± 1.229
3.155AsnMet: 3.155 ± 2.349
3.155AsnAsn: 3.155 ± 0.054
3.155AsnPro: 3.155 ± 0.054
1.577AsnGln: 1.577 ± 1.175
3.155AsnArg: 3.155 ± 2.241
3.155AsnSer: 3.155 ± 0.054
3.155AsnThr: 3.155 ± 2.349
4.732AsnVal: 4.732 ± 1.229
0.0AsnTrp: 0.0 ± 0.0
1.577AsnTyr: 1.577 ± 1.175
0.0AsnXaa: 0.0 ± 0.0
Pro
3.155ProAla: 3.155 ± 2.241
1.577ProCys: 1.577 ± 1.12
1.577ProAsp: 1.577 ± 1.12
0.0ProGlu: 0.0 ± 0.0
0.0ProPhe: 0.0 ± 0.0
4.732ProGly: 4.732 ± 1.229
1.577ProHis: 1.577 ± 1.175
1.577ProIle: 1.577 ± 1.175
0.0ProLys: 0.0 ± 0.0
1.577ProLeu: 1.577 ± 1.12
0.0ProMet: 0.0 ± 0.0
4.732ProAsn: 4.732 ± 1.066
1.577ProPro: 1.577 ± 1.12
1.577ProGln: 1.577 ± 1.12
6.309ProArg: 6.309 ± 4.699
4.732ProSer: 4.732 ± 1.229
1.577ProThr: 1.577 ± 1.175
1.577ProVal: 1.577 ± 1.175
1.577ProTrp: 1.577 ± 1.175
4.732ProTyr: 4.732 ± 1.066
0.0ProXaa: 0.0 ± 0.0
Gln
6.309GlnAla: 6.309 ± 0.109
1.577GlnCys: 1.577 ± 1.12
3.155GlnAsp: 3.155 ± 0.054
1.577GlnGlu: 1.577 ± 1.12
1.577GlnPhe: 1.577 ± 1.175
4.732GlnGly: 4.732 ± 1.229
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
0.0GlnLys: 0.0 ± 0.0
4.732GlnLeu: 4.732 ± 1.066
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
4.732GlnPro: 4.732 ± 3.524
3.155GlnGln: 3.155 ± 2.241
1.577GlnArg: 1.577 ± 1.175
1.577GlnSer: 1.577 ± 1.175
3.155GlnThr: 3.155 ± 0.054
1.577GlnVal: 1.577 ± 1.12
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.155ArgAla: 3.155 ± 2.241
0.0ArgCys: 0.0 ± 0.0
4.732ArgAsp: 4.732 ± 1.066
3.155ArgGlu: 3.155 ± 2.241
7.886ArgPhe: 7.886 ± 3.578
6.309ArgGly: 6.309 ± 2.187
1.577ArgHis: 1.577 ± 1.175
4.732ArgIle: 4.732 ± 1.229
7.886ArgLys: 7.886 ± 1.012
1.577ArgLeu: 1.577 ± 1.12
1.577ArgMet: 1.577 ± 1.175
4.732ArgAsn: 4.732 ± 1.229
9.464ArgPro: 9.464 ± 2.132
0.0ArgGln: 0.0 ± 0.0
25.237ArgArg: 25.237 ± 16.5
9.464ArgSer: 9.464 ± 0.163
9.464ArgThr: 9.464 ± 2.132
7.886ArgVal: 7.886 ± 3.578
0.0ArgTrp: 0.0 ± 0.0
4.732ArgTyr: 4.732 ± 1.229
0.0ArgXaa: 0.0 ± 0.0
Ser
4.732SerAla: 4.732 ± 1.229
0.0SerCys: 0.0 ± 0.0
3.155SerAsp: 3.155 ± 2.349
4.732SerGlu: 4.732 ± 1.066
7.886SerPhe: 7.886 ± 3.307
9.464SerGly: 9.464 ± 7.048
3.155SerHis: 3.155 ± 2.241
3.155SerIle: 3.155 ± 2.349
3.155SerLys: 3.155 ± 2.349
4.732SerLeu: 4.732 ± 3.361
0.0SerMet: 0.0 ± 0.0
1.577SerAsn: 1.577 ± 1.175
6.309SerPro: 6.309 ± 4.699
4.732SerGln: 4.732 ± 1.229
11.041SerArg: 11.041 ± 0.958
9.464SerSer: 9.464 ± 4.753
3.155SerThr: 3.155 ± 2.349
0.0SerVal: 0.0 ± 0.0
1.577SerTrp: 1.577 ± 1.12
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
7.886ThrAla: 7.886 ± 1.283
0.0ThrCys: 0.0 ± 0.0
3.155ThrAsp: 3.155 ± 0.054
0.0ThrGlu: 0.0 ± 0.0
4.732ThrPhe: 4.732 ± 1.229
4.732ThrGly: 4.732 ± 1.229
3.155ThrHis: 3.155 ± 2.241
4.732ThrIle: 4.732 ± 3.524
1.577ThrLys: 1.577 ± 1.12
0.0ThrLeu: 0.0 ± 0.0
1.577ThrMet: 1.577 ± 1.175
3.155ThrAsn: 3.155 ± 2.349
6.309ThrPro: 6.309 ± 2.404
1.577ThrGln: 1.577 ± 1.12
6.309ThrArg: 6.309 ± 0.109
3.155ThrSer: 3.155 ± 0.054
3.155ThrThr: 3.155 ± 2.349
0.0ThrVal: 0.0 ± 0.0
1.577ThrTrp: 1.577 ± 1.12
3.155ThrTyr: 3.155 ± 0.054
0.0ThrXaa: 0.0 ± 0.0
Val
1.577ValAla: 1.577 ± 1.175
0.0ValCys: 0.0 ± 0.0
4.732ValAsp: 4.732 ± 3.361
1.577ValGlu: 1.577 ± 1.12
4.732ValPhe: 4.732 ± 1.066
0.0ValGly: 0.0 ± 0.0
1.577ValHis: 1.577 ± 1.12
1.577ValIle: 1.577 ± 1.175
3.155ValLys: 3.155 ± 0.054
0.0ValLeu: 0.0 ± 0.0
3.155ValMet: 3.155 ± 2.99
1.577ValAsn: 1.577 ± 1.175
1.577ValPro: 1.577 ± 1.12
1.577ValGln: 1.577 ± 1.175
3.155ValArg: 3.155 ± 2.349
3.155ValSer: 3.155 ± 0.054
3.155ValThr: 3.155 ± 0.054
0.0ValVal: 0.0 ± 0.0
1.577ValTrp: 1.577 ± 1.175
3.155ValTyr: 3.155 ± 2.349
0.0ValXaa: 0.0 ± 0.0
Trp
1.577TrpAla: 1.577 ± 1.175
0.0TrpCys: 0.0 ± 0.0
3.155TrpAsp: 3.155 ± 2.241
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
3.155TrpGly: 3.155 ± 2.241
1.577TrpHis: 1.577 ± 1.175
3.155TrpIle: 3.155 ± 2.241
1.577TrpLys: 1.577 ± 1.12
4.732TrpLeu: 4.732 ± 3.361
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.577TrpArg: 1.577 ± 1.175
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
1.577TrpVal: 1.577 ± 1.175
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.309TyrAla: 6.309 ± 2.187
1.577TyrCys: 1.577 ± 1.12
3.155TyrAsp: 3.155 ± 2.349
3.155TyrGlu: 3.155 ± 0.054
3.155TyrPhe: 3.155 ± 2.241
4.732TyrGly: 4.732 ± 1.229
0.0TyrHis: 0.0 ± 0.0
3.155TyrIle: 3.155 ± 2.241
1.577TyrLys: 1.577 ± 1.12
1.577TyrLeu: 1.577 ± 1.175
0.0TyrMet: 0.0 ± 0.0
3.155TyrAsn: 3.155 ± 0.054
0.0TyrPro: 0.0 ± 0.0
1.577TyrGln: 1.577 ± 1.12
6.309TyrArg: 6.309 ± 2.404
3.155TyrSer: 3.155 ± 0.054
1.577TyrThr: 1.577 ± 1.12
0.0TyrVal: 0.0 ± 0.0
1.577TyrTrp: 1.577 ± 1.175
1.577TyrTyr: 1.577 ± 1.175
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (635 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski