Amino acid dipepetide frequency for Tamlana fucoidanivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.925AlaAla: 3.925 ± 0.069	0.629AlaCys: 0.629 ± 0.021	3.175AlaAsp: 3.175 ± 0.055	3.803AlaGlu: 3.803 ± 0.059	3.437AlaPhe: 3.437 ± 0.06	3.97AlaGly: 3.97 ± 0.068	1.299AlaHis: 1.299 ± 0.032	5.292AlaIle: 5.292 ± 0.079	4.559AlaLys: 4.559 ± 0.068	6.312AlaLeu: 6.312 ± 0.076	1.492AlaMet: 1.492 ± 0.044	3.416AlaAsn: 3.416 ± 0.061	2.056AlaPro: 2.056 ± 0.051	2.451AlaGln: 2.451 ± 0.048	1.972AlaArg: 1.972 ± 0.046	4.37AlaSer: 4.37 ± 0.071	3.373AlaThr: 3.373 ± 0.062	4.033AlaVal: 4.033 ± 0.068	0.671AlaTrp: 0.671 ± 0.024	2.682AlaTyr: 2.682 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.471CysAla: 0.471 ± 0.021	0.11CysCys: 0.11 ± 0.011	0.469CysAsp: 0.469 ± 0.023	0.458CysGlu: 0.458 ± 0.02	0.491CysPhe: 0.491 ± 0.022	0.582CysGly: 0.582 ± 0.023	0.251CysHis: 0.251 ± 0.021	0.617CysIle: 0.617 ± 0.023	0.543CysLys: 0.543 ± 0.023	0.724CysLeu: 0.724 ± 0.026	0.177CysMet: 0.177 ± 0.012	0.425CysAsn: 0.425 ± 0.021	0.327CysPro: 0.327 ± 0.021	0.247CysGln: 0.247 ± 0.015	0.214CysArg: 0.214 ± 0.015	0.562CysSer: 0.562 ± 0.022	0.425CysThr: 0.425 ± 0.028	0.506CysVal: 0.506 ± 0.021	0.076CysTrp: 0.076 ± 0.007	0.354CysTyr: 0.354 ± 0.019	0.0CysXaa: 0.0 ± 0.0
Asp	3.913AspAla: 3.913 ± 0.066	0.42AspCys: 0.42 ± 0.019	3.225AspAsp: 3.225 ± 0.056	3.542AspGlu: 3.542 ± 0.048	3.691AspPhe: 3.691 ± 0.061	3.843AspGly: 3.843 ± 0.079	0.955AspHis: 0.955 ± 0.029	4.814AspIle: 4.814 ± 0.062	4.077AspLys: 4.077 ± 0.062	5.275AspLeu: 5.275 ± 0.07	1.235AspMet: 1.235 ± 0.032	3.193AspAsn: 3.193 ± 0.062	1.63AspPro: 1.63 ± 0.04	1.379AspGln: 1.379 ± 0.034	1.804AspArg: 1.804 ± 0.043	3.061AspSer: 3.061 ± 0.056	2.811AspThr: 2.811 ± 0.05	3.84AspVal: 3.84 ± 0.062	0.862AspTrp: 0.862 ± 0.031	2.983AspTyr: 2.983 ± 0.053	0.0AspXaa: 0.0 ± 0.0
Glu	4.693GluAla: 4.693 ± 0.073	0.338GluCys: 0.338 ± 0.015	3.707GluAsp: 3.707 ± 0.057	4.278GluGlu: 4.278 ± 0.076	2.841GluPhe: 2.841 ± 0.057	3.712GluGly: 3.712 ± 0.059	1.348GluHis: 1.348 ± 0.035	4.776GluIle: 4.776 ± 0.063	5.051GluLys: 5.051 ± 0.076	5.901GluLeu: 5.901 ± 0.081	1.356GluMet: 1.356 ± 0.033	4.393GluAsn: 4.393 ± 0.07	1.707GluPro: 1.707 ± 0.043	2.317GluGln: 2.317 ± 0.047	2.445GluArg: 2.445 ± 0.051	3.406GluSer: 3.406 ± 0.054	3.802GluThr: 3.802 ± 0.055	4.157GluVal: 4.157 ± 0.063	0.656GluTrp: 0.656 ± 0.026	2.229GluTyr: 2.229 ± 0.04	0.0GluXaa: 0.0 ± 0.0
Phe	2.733PheAla: 2.733 ± 0.053	0.474PheCys: 0.474 ± 0.019	3.301PheAsp: 3.301 ± 0.054	3.46PheGlu: 3.46 ± 0.05	2.635PhePhe: 2.635 ± 0.06	3.605PheGly: 3.605 ± 0.07	0.904PheHis: 0.904 ± 0.028	3.914PheIle: 3.914 ± 0.066	4.188PheLys: 4.188 ± 0.071	4.478PheLeu: 4.478 ± 0.071	1.108PheMet: 1.108 ± 0.028	3.606PheAsn: 3.606 ± 0.064	1.77PhePro: 1.77 ± 0.038	1.571PheGln: 1.571 ± 0.039	1.633PheArg: 1.633 ± 0.04	3.941PheSer: 3.941 ± 0.052	2.919PheThr: 2.919 ± 0.051	3.07PheVal: 3.07 ± 0.06	0.641PheTrp: 0.641 ± 0.023	2.219PheTyr: 2.219 ± 0.05	0.0PheXaa: 0.0 ± 0.0
Gly	4.267GlyAla: 4.267 ± 0.073	0.658GlyCys: 0.658 ± 0.035	3.534GlyAsp: 3.534 ± 0.061	3.556GlyGlu: 3.556 ± 0.055	3.693GlyPhe: 3.693 ± 0.064	4.555GlyGly: 4.555 ± 0.082	1.314GlyHis: 1.314 ± 0.034	5.247GlyIle: 5.247 ± 0.073	4.944GlyLys: 4.944 ± 0.066	5.896GlyLeu: 5.896 ± 0.072	1.592GlyMet: 1.592 ± 0.04	3.537GlyAsn: 3.537 ± 0.065	1.516GlyPro: 1.516 ± 0.041	1.942GlyGln: 1.942 ± 0.042	2.148GlyArg: 2.148 ± 0.048	3.918GlySer: 3.918 ± 0.061	3.866GlyThr: 3.866 ± 0.077	4.656GlyVal: 4.656 ± 0.079	0.892GlyTrp: 0.892 ± 0.03	2.962GlyTyr: 2.962 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.215HisAla: 1.215 ± 0.032	0.196HisCys: 0.196 ± 0.014	1.118HisAsp: 1.118 ± 0.036	1.068HisGlu: 1.068 ± 0.03	1.298HisPhe: 1.298 ± 0.037	1.241HisGly: 1.241 ± 0.032	0.586HisHis: 0.586 ± 0.024	1.635HisIle: 1.635 ± 0.037	1.343HisLys: 1.343 ± 0.036	1.975HisLeu: 1.975 ± 0.043	0.393HisMet: 0.393 ± 0.019	1.127HisAsn: 1.127 ± 0.031	0.962HisPro: 0.962 ± 0.03	0.754HisGln: 0.754 ± 0.027	0.688HisArg: 0.688 ± 0.025	1.134HisSer: 1.134 ± 0.033	1.085HisThr: 1.085 ± 0.029	1.24HisVal: 1.24 ± 0.034	0.298HisTrp: 0.298 ± 0.017	0.955HisTyr: 0.955 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.11IleAla: 5.11 ± 0.074	0.618IleCys: 0.618 ± 0.023	4.997IleAsp: 4.997 ± 0.064	5.531IleGlu: 5.531 ± 0.07	3.314IlePhe: 3.314 ± 0.063	5.069IleGly: 5.069 ± 0.082	1.448IleHis: 1.448 ± 0.036	5.785IleIle: 5.785 ± 0.084	6.026IleLys: 6.026 ± 0.08	6.696IleLeu: 6.696 ± 0.091	1.468IleMet: 1.468 ± 0.038	4.867IleAsn: 4.867 ± 0.067	3.224IlePro: 3.224 ± 0.054	2.448IleGln: 2.448 ± 0.046	2.439IleArg: 2.439 ± 0.044	5.527IleSer: 5.527 ± 0.08	4.728IleThr: 4.728 ± 0.067	4.651IleVal: 4.651 ± 0.066	0.758IleTrp: 0.758 ± 0.025	2.787IleTyr: 2.787 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	5.289LysAla: 5.289 ± 0.072	0.356LysCys: 0.356 ± 0.02	4.521LysAsp: 4.521 ± 0.075	5.492LysGlu: 5.492 ± 0.061	2.967LysPhe: 2.967 ± 0.05	4.536LysGly: 4.536 ± 0.063	1.823LysHis: 1.823 ± 0.045	5.62LysIle: 5.62 ± 0.071	6.357LysLys: 6.357 ± 0.091	6.704LysLeu: 6.704 ± 0.089	1.803LysMet: 1.803 ± 0.039	5.222LysAsn: 5.222 ± 0.076	2.753LysPro: 2.753 ± 0.047	3.063LysGln: 3.063 ± 0.058	3.121LysArg: 3.121 ± 0.053	4.644LysSer: 4.644 ± 0.061	5.039LysThr: 5.039 ± 0.068	4.712LysVal: 4.712 ± 0.07	0.852LysTrp: 0.852 ± 0.029	3.034LysTyr: 3.034 ± 0.052	0.0LysXaa: 0.0 ± 0.0
Leu	5.492LeuAla: 5.492 ± 0.07	0.761LeuCys: 0.761 ± 0.025	4.992LeuAsp: 4.992 ± 0.065	5.918LeuGlu: 5.918 ± 0.071	4.756LeuPhe: 4.756 ± 0.08	5.939LeuGly: 5.939 ± 0.079	1.633LeuHis: 1.633 ± 0.034	6.797LeuIle: 6.797 ± 0.093	8.128LeuLys: 8.128 ± 0.097	8.077LeuLeu: 8.077 ± 0.112	1.988LeuMet: 1.988 ± 0.04	6.09LeuAsn: 6.09 ± 0.077	3.5LeuPro: 3.5 ± 0.053	2.998LeuGln: 2.998 ± 0.057	3.126LeuArg: 3.126 ± 0.052	6.493LeuSer: 6.493 ± 0.07	4.861LeuThr: 4.861 ± 0.063	5.505LeuVal: 5.505 ± 0.076	0.93LeuTrp: 0.93 ± 0.028	3.253LeuTyr: 3.253 ± 0.062	0.0LeuXaa: 0.0 ± 0.0
Met	1.618MetAla: 1.618 ± 0.039	0.16MetCys: 0.16 ± 0.01	1.037MetAsp: 1.037 ± 0.031	1.122MetGlu: 1.122 ± 0.029	0.911MetPhe: 0.911 ± 0.026	1.403MetGly: 1.403 ± 0.039	0.435MetHis: 0.435 ± 0.021	1.484MetIle: 1.484 ± 0.035	2.028MetLys: 2.028 ± 0.037	1.976MetLeu: 1.976 ± 0.046	0.514MetMet: 0.514 ± 0.025	1.23MetAsn: 1.23 ± 0.037	0.898MetPro: 0.898 ± 0.03	0.791MetGln: 0.791 ± 0.027	0.862MetArg: 0.862 ± 0.029	1.456MetSer: 1.456 ± 0.037	1.196MetThr: 1.196 ± 0.032	1.374MetVal: 1.374 ± 0.042	0.188MetTrp: 0.188 ± 0.013	0.801MetTyr: 0.801 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.806AsnAla: 3.806 ± 0.059	0.472AsnCys: 0.472 ± 0.021	3.457AsnAsp: 3.457 ± 0.062	3.635AsnGlu: 3.635 ± 0.056	3.003AsnPhe: 3.003 ± 0.058	4.161AsnGly: 4.161 ± 0.073	1.311AsnHis: 1.311 ± 0.033	5.096AsnIle: 5.096 ± 0.08	4.686AsnLys: 4.686 ± 0.07	5.345AsnLeu: 5.345 ± 0.058	1.341AsnMet: 1.341 ± 0.033	4.197AsnAsn: 4.197 ± 0.071	2.828AsnPro: 2.828 ± 0.051	2.359AsnGln: 2.359 ± 0.045	2.265AsnArg: 2.265 ± 0.049	3.745AsnSer: 3.745 ± 0.069	4.004AsnThr: 4.004 ± 0.064	3.6AsnVal: 3.6 ± 0.068	0.862AsnTrp: 0.862 ± 0.026	2.904AsnTyr: 2.904 ± 0.055	0.0AsnXaa: 0.0 ± 0.0
Pro	1.765ProAla: 1.765 ± 0.04	0.218ProCys: 0.218 ± 0.016	2.157ProAsp: 2.157 ± 0.047	3.039ProGlu: 3.039 ± 0.05	1.97ProPhe: 1.97 ± 0.036	1.93ProGly: 1.93 ± 0.047	0.735ProHis: 0.735 ± 0.024	2.63ProIle: 2.63 ± 0.048	2.734ProLys: 2.734 ± 0.048	3.016ProLeu: 3.016 ± 0.049	0.727ProMet: 0.727 ± 0.026	2.539ProAsn: 2.539 ± 0.052	0.825ProPro: 0.825 ± 0.027	1.088ProGln: 1.088 ± 0.028	1.067ProArg: 1.067 ± 0.03	2.301ProSer: 2.301 ± 0.044	1.927ProThr: 1.927 ± 0.048	2.353ProVal: 2.353 ± 0.049	0.456ProTrp: 0.456 ± 0.023	1.508ProTyr: 1.508 ± 0.043	0.0ProXaa: 0.0 ± 0.0
Gln	2.139GlnAla: 2.139 ± 0.05	0.2GlnCys: 0.2 ± 0.015	1.82GlnAsp: 1.82 ± 0.043	2.157GlnGlu: 2.157 ± 0.048	1.692GlnPhe: 1.692 ± 0.034	2.037GlnGly: 2.037 ± 0.042	0.7GlnHis: 0.7 ± 0.024	2.607GlnIle: 2.607 ± 0.052	2.55GlnLys: 2.55 ± 0.057	3.377GlnLeu: 3.377 ± 0.055	0.74GlnMet: 0.74 ± 0.025	2.228GlnAsn: 2.228 ± 0.049	1.152GlnPro: 1.152 ± 0.031	1.258GlnGln: 1.258 ± 0.032	1.257GlnArg: 1.257 ± 0.033	1.902GlnSer: 1.902 ± 0.044	1.829GlnThr: 1.829 ± 0.043	2.075GlnVal: 2.075 ± 0.038	0.395GlnTrp: 0.395 ± 0.016	1.397GlnTyr: 1.397 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.204ArgAla: 2.204 ± 0.044	0.235ArgCys: 0.235 ± 0.013	1.854ArgAsp: 1.854 ± 0.037	2.003ArgGlu: 2.003 ± 0.047	1.979ArgPhe: 1.979 ± 0.04	2.048ArgGly: 2.048 ± 0.042	0.749ArgHis: 0.749 ± 0.026	2.743ArgIle: 2.743 ± 0.045	2.543ArgLys: 2.543 ± 0.05	3.329ArgLeu: 3.329 ± 0.058	0.852ArgMet: 0.852 ± 0.029	2.011ArgAsn: 2.011 ± 0.041	1.189ArgPro: 1.189 ± 0.035	1.126ArgGln: 1.126 ± 0.035	1.387ArgArg: 1.387 ± 0.036	1.908ArgSer: 1.908 ± 0.043	1.908ArgThr: 1.908 ± 0.04	2.205ArgVal: 2.205 ± 0.05	0.462ArgTrp: 0.462 ± 0.02	1.62ArgTyr: 1.62 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	3.672SerAla: 3.672 ± 0.059	0.701SerCys: 0.701 ± 0.027	3.45SerAsp: 3.45 ± 0.049	3.995SerGlu: 3.995 ± 0.061	3.681SerPhe: 3.681 ± 0.068	4.636SerGly: 4.636 ± 0.08	1.296SerHis: 1.296 ± 0.034	5.107SerIle: 5.107 ± 0.071	5.311SerLys: 5.311 ± 0.071	5.65SerLeu: 5.65 ± 0.064	1.29SerMet: 1.29 ± 0.036	4.068SerAsn: 4.068 ± 0.07	2.045SerPro: 2.045 ± 0.041	2.161SerGln: 2.161 ± 0.041	2.139SerArg: 2.139 ± 0.041	4.142SerSer: 4.142 ± 0.08	3.401SerThr: 3.401 ± 0.056	3.931SerVal: 3.931 ± 0.053	0.81SerTrp: 0.81 ± 0.03	2.707SerTyr: 2.707 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	3.389ThrAla: 3.389 ± 0.068	0.43ThrCys: 0.43 ± 0.021	3.126ThrAsp: 3.126 ± 0.059	3.154ThrGlu: 3.154 ± 0.049	3.12ThrPhe: 3.12 ± 0.052	3.956ThrGly: 3.956 ± 0.077	1.155ThrHis: 1.155 ± 0.03	4.908ThrIle: 4.908 ± 0.064	3.987ThrLys: 3.987 ± 0.061	5.418ThrLeu: 5.418 ± 0.069	0.98ThrMet: 0.98 ± 0.03	3.429ThrAsn: 3.429 ± 0.062	2.512ThrPro: 2.512 ± 0.054	1.829ThrGln: 1.829 ± 0.042	1.667ThrArg: 1.667 ± 0.039	3.838ThrSer: 3.838 ± 0.051	3.27ThrThr: 3.27 ± 0.062	3.683ThrVal: 3.683 ± 0.072	0.685ThrTrp: 0.685 ± 0.025	2.574ThrTyr: 2.574 ± 0.054	0.0ThrXaa: 0.0 ± 0.0
Val	3.996ValAla: 3.996 ± 0.069	0.579ValCys: 0.579 ± 0.027	3.604ValAsp: 3.604 ± 0.057	3.906ValGlu: 3.906 ± 0.064	3.57ValPhe: 3.57 ± 0.048	3.874ValGly: 3.874 ± 0.073	1.109ValHis: 1.109 ± 0.028	4.786ValIle: 4.786 ± 0.065	4.68ValLys: 4.68 ± 0.067	6.268ValLeu: 6.268 ± 0.079	1.3ValMet: 1.3 ± 0.035	3.808ValAsn: 3.808 ± 0.063	2.203ValPro: 2.203 ± 0.046	1.676ValGln: 1.676 ± 0.034	1.977ValArg: 1.977 ± 0.043	4.564ValSer: 4.564 ± 0.07	3.55ValThr: 3.55 ± 0.084	4.345ValVal: 4.345 ± 0.081	0.663ValTrp: 0.663 ± 0.027	2.551ValTyr: 2.551 ± 0.049	0.0ValXaa: 0.0 ± 0.0
Trp	0.683TrpAla: 0.683 ± 0.027	0.13TrpCys: 0.13 ± 0.011	0.695TrpAsp: 0.695 ± 0.023	0.706TrpGlu: 0.706 ± 0.025	0.641TrpPhe: 0.641 ± 0.027	0.815TrpGly: 0.815 ± 0.03	0.327TrpHis: 0.327 ± 0.017	0.789TrpIle: 0.789 ± 0.029	0.854TrpLys: 0.854 ± 0.031	1.051TrpLeu: 1.051 ± 0.032	0.329TrpMet: 0.329 ± 0.018	0.795TrpAsn: 0.795 ± 0.029	0.312TrpPro: 0.312 ± 0.016	0.488TrpGln: 0.488 ± 0.019	0.479TrpArg: 0.479 ± 0.018	0.747TrpSer: 0.747 ± 0.024	0.606TrpThr: 0.606 ± 0.024	0.73TrpVal: 0.73 ± 0.026	0.179TrpTrp: 0.179 ± 0.013	0.522TrpTyr: 0.522 ± 0.024	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.535TyrAla: 2.535 ± 0.045	0.346TyrCys: 0.346 ± 0.016	2.31TyrAsp: 2.31 ± 0.045	2.292TyrGlu: 2.292 ± 0.043	2.481TyrPhe: 2.481 ± 0.047	2.782TyrGly: 2.782 ± 0.047	0.933TyrHis: 0.933 ± 0.029	2.841TyrIle: 2.841 ± 0.05	3.319TyrLys: 3.319 ± 0.059	3.771TyrLeu: 3.771 ± 0.053	0.797TyrMet: 0.797 ± 0.026	2.895TyrAsn: 2.895 ± 0.051	1.572TyrPro: 1.572 ± 0.038	1.568TyrGln: 1.568 ± 0.039	1.666TyrArg: 1.666 ± 0.048	2.536TyrSer: 2.536 ± 0.048	2.512TyrThr: 2.512 ± 0.052	2.344TyrVal: 2.344 ± 0.044	0.542TyrTrp: 0.542 ± 0.025	1.938TyrTyr: 1.938 ± 0.048	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3334 proteins (1203641 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---