Amino acid dipepetide frequency for Leptotrombidium deliense

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.17AlaAla: 4.17 ± 0.038	1.063AlaCys: 1.063 ± 0.016	2.682AlaAsp: 2.682 ± 0.022	3.287AlaGlu: 3.287 ± 0.027	2.916AlaPhe: 2.916 ± 0.025	2.611AlaGly: 2.611 ± 0.027	1.182AlaHis: 1.182 ± 0.016	4.095AlaIle: 4.095 ± 0.028	4.044AlaLys: 4.044 ± 0.032	5.259AlaLeu: 5.259 ± 0.037	1.416AlaMet: 1.416 ± 0.019	3.271AlaAsn: 3.271 ± 0.026	1.996AlaPro: 1.996 ± 0.024	1.835AlaGln: 1.835 ± 0.023	2.152AlaArg: 2.152 ± 0.022	4.435AlaSer: 4.435 ± 0.031	3.324AlaThr: 3.324 ± 0.028	4.121AlaVal: 4.121 ± 0.03	0.502AlaTrp: 0.502 ± 0.012	1.732AlaTyr: 1.732 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	1.151CysAla: 1.151 ± 0.017	0.604CysCys: 0.604 ± 0.015	1.547CysAsp: 1.547 ± 0.023	1.542CysGlu: 1.542 ± 0.021	1.141CysPhe: 1.141 ± 0.017	1.474CysGly: 1.474 ± 0.021	0.539CysHis: 0.539 ± 0.012	1.383CysIle: 1.383 ± 0.02	1.512CysLys: 1.512 ± 0.024	2.095CysLeu: 2.095 ± 0.024	0.408CysMet: 0.408 ± 0.009	1.277CysAsn: 1.277 ± 0.019	1.013CysPro: 1.013 ± 0.021	0.759CysGln: 0.759 ± 0.015	1.078CysArg: 1.078 ± 0.016	1.765CysSer: 1.765 ± 0.022	1.025CysThr: 1.025 ± 0.017	1.611CysVal: 1.611 ± 0.022	0.255CysTrp: 0.255 ± 0.008	0.76CysTyr: 0.76 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	3.032AspAla: 3.032 ± 0.026	1.295AspCys: 1.295 ± 0.019	3.636AspAsp: 3.636 ± 0.04	4.561AspGlu: 4.561 ± 0.039	2.682AspPhe: 2.682 ± 0.027	2.933AspGly: 2.933 ± 0.03	1.062AspHis: 1.062 ± 0.014	3.644AspIle: 3.644 ± 0.026	3.34AspLys: 3.34 ± 0.027	4.704AspLeu: 4.704 ± 0.03	1.083AspMet: 1.083 ± 0.016	2.787AspAsn: 2.787 ± 0.024	1.962AspPro: 1.962 ± 0.019	1.45AspGln: 1.45 ± 0.018	2.152AspArg: 2.152 ± 0.025	4.223AspSer: 4.223 ± 0.036	2.578AspThr: 2.578 ± 0.022	3.844AspVal: 3.844 ± 0.029	0.674AspTrp: 0.674 ± 0.012	2.098AspTyr: 2.098 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	3.671GluAla: 3.671 ± 0.031	1.528GluCys: 1.528 ± 0.02	3.499GluAsp: 3.499 ± 0.035	5.32GluGlu: 5.32 ± 0.058	2.65GluPhe: 2.65 ± 0.026	2.508GluGly: 2.508 ± 0.024	1.351GluHis: 1.351 ± 0.016	4.373GluIle: 4.373 ± 0.035	5.58GluLys: 5.58 ± 0.044	5.5GluLeu: 5.5 ± 0.045	1.854GluMet: 1.854 ± 0.022	4.445GluAsn: 4.445 ± 0.039	1.931GluPro: 1.931 ± 0.022	2.469GluGln: 2.469 ± 0.024	3.232GluArg: 3.232 ± 0.03	4.964GluSer: 4.964 ± 0.039	3.893GluThr: 3.893 ± 0.029	3.795GluVal: 3.795 ± 0.029	0.706GluTrp: 0.706 ± 0.01	2.258GluTyr: 2.258 ± 0.027	0.0GluXaa: 0.0 ± 0.0
Phe	2.908PheAla: 2.908 ± 0.028	1.095PheCys: 1.095 ± 0.017	2.973PheAsp: 2.973 ± 0.025	3.098PheGlu: 3.098 ± 0.032	2.036PhePhe: 2.036 ± 0.025	2.876PheGly: 2.876 ± 0.024	1.157PheHis: 1.157 ± 0.015	3.081PheIle: 3.081 ± 0.026	2.981PheLys: 2.981 ± 0.025	4.084PheLeu: 4.084 ± 0.036	1.026PheMet: 1.026 ± 0.016	2.587PheAsn: 2.587 ± 0.022	1.812PhePro: 1.812 ± 0.019	1.624PheGln: 1.624 ± 0.02	2.17PheArg: 2.17 ± 0.022	3.614PheSer: 3.614 ± 0.033	2.709PheThr: 2.709 ± 0.025	3.461PheVal: 3.461 ± 0.026	0.577PheTrp: 0.577 ± 0.012	1.679PheTyr: 1.679 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	2.703GlyAla: 2.703 ± 0.027	1.094GlyCys: 1.094 ± 0.02	2.79GlyAsp: 2.79 ± 0.032	2.958GlyGlu: 2.958 ± 0.033	2.582GlyPhe: 2.582 ± 0.032	3.025GlyGly: 3.025 ± 0.038	1.288GlyHis: 1.288 ± 0.02	3.308GlyIle: 3.308 ± 0.029	3.592GlyLys: 3.592 ± 0.032	4.047GlyLeu: 4.047 ± 0.039	1.028GlyMet: 1.028 ± 0.016	2.863GlyAsn: 2.863 ± 0.026	1.75GlyPro: 1.75 ± 0.032	1.62GlyGln: 1.62 ± 0.02	2.364GlyArg: 2.364 ± 0.028	3.987GlySer: 3.987 ± 0.036	2.734GlyThr: 2.734 ± 0.026	3.241GlyVal: 3.241 ± 0.027	0.581GlyTrp: 0.581 ± 0.011	1.977GlyTyr: 1.977 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.019HisAla: 1.019 ± 0.015	0.662HisCys: 0.662 ± 0.013	0.983HisAsp: 0.983 ± 0.016	1.383HisGlu: 1.383 ± 0.017	1.319HisPhe: 1.319 ± 0.016	1.145HisGly: 1.145 ± 0.016	0.689HisHis: 0.689 ± 0.015	1.516HisIle: 1.516 ± 0.018	1.517HisLys: 1.517 ± 0.017	2.417HisLeu: 2.417 ± 0.022	0.473HisMet: 0.473 ± 0.012	1.224HisAsn: 1.224 ± 0.016	1.079HisPro: 1.079 ± 0.016	0.912HisGln: 0.912 ± 0.017	1.25HisArg: 1.25 ± 0.017	2.099HisSer: 2.099 ± 0.022	1.172HisThr: 1.172 ± 0.015	1.368HisVal: 1.368 ± 0.02	0.313HisTrp: 0.313 ± 0.009	0.907HisTyr: 0.907 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.253IleAla: 4.253 ± 0.032	1.529IleCys: 1.529 ± 0.019	3.987IleAsp: 3.987 ± 0.027	4.348IleGlu: 4.348 ± 0.031	2.874IlePhe: 2.874 ± 0.024	3.37IleGly: 3.37 ± 0.029	1.609IleHis: 1.609 ± 0.019	4.2IleIle: 4.2 ± 0.036	4.136IleLys: 4.136 ± 0.033	5.524IleLeu: 5.524 ± 0.035	1.263IleMet: 1.263 ± 0.016	3.662IleAsn: 3.662 ± 0.029	2.933IlePro: 2.933 ± 0.023	2.245IleGln: 2.245 ± 0.022	3.129IleArg: 3.129 ± 0.027	5.008IleSer: 5.008 ± 0.03	3.767IleThr: 3.767 ± 0.028	4.247IleVal: 4.247 ± 0.034	0.69IleTrp: 0.69 ± 0.013	2.122IleTyr: 2.122 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	3.778LysAla: 3.778 ± 0.033	1.828LysCys: 1.828 ± 0.024	3.565LysAsp: 3.565 ± 0.03	5.044LysGlu: 5.044 ± 0.04	2.952LysPhe: 2.952 ± 0.025	3.112LysGly: 3.112 ± 0.033	1.853LysHis: 1.853 ± 0.018	4.424LysIle: 4.424 ± 0.03	5.404LysLys: 5.404 ± 0.05	6.684LysLeu: 6.684 ± 0.041	1.746LysMet: 1.746 ± 0.017	3.96LysAsn: 3.96 ± 0.028	2.912LysPro: 2.912 ± 0.031	3.238LysGln: 3.238 ± 0.029	3.985LysArg: 3.985 ± 0.033	5.461LysSer: 5.461 ± 0.036	3.791LysThr: 3.791 ± 0.031	4.298LysVal: 4.298 ± 0.033	0.875LysTrp: 0.875 ± 0.014	2.71LysTyr: 2.71 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	4.545LeuAla: 4.545 ± 0.033	2.005LeuCys: 2.005 ± 0.024	4.187LeuAsp: 4.187 ± 0.034	5.23LeuGlu: 5.23 ± 0.041	4.428LeuPhe: 4.428 ± 0.038	3.839LeuGly: 3.839 ± 0.031	2.234LeuHis: 2.234 ± 0.027	5.857LeuIle: 5.857 ± 0.041	7.193LeuLys: 7.193 ± 0.048	9.014LeuLeu: 9.014 ± 0.053	2.286LeuMet: 2.286 ± 0.022	5.377LeuAsn: 5.377 ± 0.038	3.996LeuPro: 3.996 ± 0.033	4.041LeuGln: 4.041 ± 0.034	4.834LeuArg: 4.834 ± 0.038	7.296LeuSer: 7.296 ± 0.042	5.082LeuThr: 5.082 ± 0.03	5.165LeuVal: 5.165 ± 0.032	0.995LeuTrp: 0.995 ± 0.014	2.875LeuTyr: 2.875 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	1.351MetAla: 1.351 ± 0.016	0.494MetCys: 0.494 ± 0.01	1.178MetAsp: 1.178 ± 0.016	1.348MetGlu: 1.348 ± 0.017	1.105MetPhe: 1.105 ± 0.015	0.917MetGly: 0.917 ± 0.015	0.512MetHis: 0.512 ± 0.01	1.327MetIle: 1.327 ± 0.014	1.909MetLys: 1.909 ± 0.02	1.963MetLeu: 1.963 ± 0.02	0.519MetMet: 0.519 ± 0.011	1.497MetAsn: 1.497 ± 0.017	0.88MetPro: 0.88 ± 0.013	0.986MetGln: 0.986 ± 0.014	1.104MetArg: 1.104 ± 0.017	1.967MetSer: 1.967 ± 0.02	1.168MetThr: 1.168 ± 0.016	1.212MetVal: 1.212 ± 0.015	0.224MetTrp: 0.224 ± 0.007	0.746MetTyr: 0.746 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.43AsnAla: 3.43 ± 0.024	1.505AsnCys: 1.505 ± 0.018	3.434AsnAsp: 3.434 ± 0.032	4.648AsnGlu: 4.648 ± 0.037	2.529AsnPhe: 2.529 ± 0.025	3.472AsnGly: 3.472 ± 0.031	1.246AsnHis: 1.246 ± 0.016	3.839AsnIle: 3.839 ± 0.029	3.804AsnLys: 3.804 ± 0.031	4.774AsnLeu: 4.774 ± 0.034	1.11AsnMet: 1.11 ± 0.015	3.575AsnAsn: 3.575 ± 0.034	2.202AsnPro: 2.202 ± 0.025	1.96AsnGln: 1.96 ± 0.026	2.602AsnArg: 2.602 ± 0.026	4.78AsnSer: 4.78 ± 0.038	2.881AsnThr: 2.881 ± 0.022	4.16AsnVal: 4.16 ± 0.026	0.674AsnTrp: 0.674 ± 0.012	2.164AsnTyr: 2.164 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	1.949ProAla: 1.949 ± 0.021	0.684ProCys: 0.684 ± 0.015	1.962ProAsp: 1.962 ± 0.022	2.588ProGlu: 2.588 ± 0.021	2.101ProPhe: 2.101 ± 0.021	2.019ProGly: 2.019 ± 0.059	0.928ProHis: 0.928 ± 0.015	2.525ProIle: 2.525 ± 0.026	2.905ProLys: 2.905 ± 0.029	3.733ProLeu: 3.733 ± 0.029	0.823ProMet: 0.823 ± 0.015	2.337ProAsn: 2.337 ± 0.025	2.583ProPro: 2.583 ± 0.043	1.719ProGln: 1.719 ± 0.021	1.704ProArg: 1.704 ± 0.02	3.465ProSer: 3.465 ± 0.035	2.302ProThr: 2.302 ± 0.028	2.618ProVal: 2.618 ± 0.028	0.402ProTrp: 0.402 ± 0.01	1.355ProTyr: 1.355 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	1.753GlnAla: 1.753 ± 0.023	0.912GlnCys: 0.912 ± 0.016	1.278GlnAsp: 1.278 ± 0.017	2.18GlnGlu: 2.18 ± 0.024	1.807GlnPhe: 1.807 ± 0.019	1.347GlnGly: 1.347 ± 0.022	0.964GlnHis: 0.964 ± 0.016	2.546GlnIle: 2.546 ± 0.026	2.793GlnLys: 2.793 ± 0.027	3.973GlnLeu: 3.973 ± 0.035	1.091GlnMet: 1.091 ± 0.015	2.176GlnAsn: 2.176 ± 0.023	1.446GlnPro: 1.446 ± 0.021	2.443GlnGln: 2.443 ± 0.042	2.252GlnArg: 2.252 ± 0.022	3.04GlnSer: 3.04 ± 0.025	2.14GlnThr: 2.14 ± 0.021	1.981GlnVal: 1.981 ± 0.023	0.496GlnTrp: 0.496 ± 0.008	1.295GlnTyr: 1.295 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	2.15ArgAla: 2.15 ± 0.02	1.114ArgCys: 1.114 ± 0.017	2.504ArgAsp: 2.504 ± 0.024	3.025ArgGlu: 3.025 ± 0.026	2.254ArgPhe: 2.254 ± 0.021	2.214ArgGly: 2.214 ± 0.03	1.214ArgHis: 1.214 ± 0.018	3.137ArgIle: 3.137 ± 0.026	4.013ArgLys: 4.013 ± 0.033	4.331ArgLeu: 4.331 ± 0.031	1.1ArgMet: 1.1 ± 0.014	3.056ArgAsn: 3.056 ± 0.029	1.731ArgPro: 1.731 ± 0.022	1.941ArgGln: 1.941 ± 0.021	3.157ArgArg: 3.157 ± 0.031	3.573ArgSer: 3.573 ± 0.033	2.324ArgThr: 2.324 ± 0.025	2.906ArgVal: 2.906 ± 0.025	0.515ArgTrp: 0.515 ± 0.011	1.689ArgTyr: 1.689 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	4.492SerAla: 4.492 ± 0.034	1.608SerCys: 1.608 ± 0.019	4.573SerAsp: 4.573 ± 0.033	4.976SerGlu: 4.976 ± 0.037	3.748SerPhe: 3.748 ± 0.031	4.288SerGly: 4.288 ± 0.032	1.854SerHis: 1.854 ± 0.019	4.737SerIle: 4.737 ± 0.028	5.517SerLys: 5.517 ± 0.035	7.457SerLeu: 7.457 ± 0.045	1.704SerMet: 1.704 ± 0.019	4.873SerAsn: 4.873 ± 0.037	3.481SerPro: 3.481 ± 0.044	3.006SerGln: 3.006 ± 0.03	3.6SerArg: 3.6 ± 0.03	7.939SerSer: 7.939 ± 0.067	4.654SerThr: 4.654 ± 0.036	5.341SerVal: 5.341 ± 0.035	0.748SerTrp: 0.748 ± 0.013	2.319SerTyr: 2.319 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	3.532ThrAla: 3.532 ± 0.031	1.181ThrCys: 1.181 ± 0.018	2.772ThrAsp: 2.772 ± 0.026	3.319ThrGlu: 3.319 ± 0.026	2.753ThrPhe: 2.753 ± 0.025	2.957ThrGly: 2.957 ± 0.029	1.236ThrHis: 1.236 ± 0.016	3.568ThrIle: 3.568 ± 0.029	3.648ThrLys: 3.648 ± 0.031	5.145ThrLeu: 5.145 ± 0.036	1.065ThrMet: 1.065 ± 0.014	3.14ThrAsn: 3.14 ± 0.029	2.646ThrPro: 2.646 ± 0.031	1.974ThrGln: 1.974 ± 0.022	2.239ThrArg: 2.239 ± 0.023	4.715ThrSer: 4.715 ± 0.038	3.514ThrThr: 3.514 ± 0.039	3.978ThrVal: 3.978 ± 0.03	0.534ThrTrp: 0.534 ± 0.012	1.623ThrTyr: 1.623 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	3.895ValAla: 3.895 ± 0.034	1.564ValCys: 1.564 ± 0.02	3.735ValAsp: 3.735 ± 0.032	3.97ValGlu: 3.97 ± 0.033	3.034ValPhe: 3.034 ± 0.023	2.966ValGly: 2.966 ± 0.03	1.515ValHis: 1.515 ± 0.021	4.457ValIle: 4.457 ± 0.034	4.583ValLys: 4.583 ± 0.035	5.432ValLeu: 5.432 ± 0.031	1.397ValMet: 1.397 ± 0.017	4.065ValAsn: 4.065 ± 0.031	2.572ValPro: 2.572 ± 0.025	2.153ValGln: 2.153 ± 0.021	2.693ValArg: 2.693 ± 0.024	4.952ValSer: 4.952 ± 0.034	4.012ValThr: 4.012 ± 0.031	4.437ValVal: 4.437 ± 0.039	0.71ValTrp: 0.71 ± 0.014	2.29ValTyr: 2.29 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	0.472TrpAla: 0.472 ± 0.011	0.256TrpCys: 0.256 ± 0.007	0.568TrpAsp: 0.568 ± 0.011	0.552TrpGlu: 0.552 ± 0.01	0.629TrpPhe: 0.629 ± 0.012	0.48TrpGly: 0.48 ± 0.011	0.237TrpHis: 0.237 ± 0.007	0.814TrpIle: 0.814 ± 0.012	0.963TrpLys: 0.963 ± 0.016	1.053TrpLeu: 1.053 ± 0.016	0.311TrpMet: 0.311 ± 0.007	0.708TrpAsn: 0.708 ± 0.012	0.396TrpPro: 0.396 ± 0.01	0.429TrpGln: 0.429 ± 0.009	0.591TrpArg: 0.591 ± 0.011	0.889TrpSer: 0.889 ± 0.014	0.651TrpThr: 0.651 ± 0.012	0.55TrpVal: 0.55 ± 0.012	0.163TrpTrp: 0.163 ± 0.007	0.383TrpTyr: 0.383 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.837TyrAla: 1.837 ± 0.023	0.919TyrCys: 0.919 ± 0.014	1.888TyrAsp: 1.888 ± 0.023	2.15TyrGlu: 2.15 ± 0.021	2.007TyrPhe: 2.007 ± 0.023	1.98TyrGly: 1.98 ± 0.023	0.779TyrHis: 0.779 ± 0.012	2.063TyrIle: 2.063 ± 0.021	2.186TyrLys: 2.186 ± 0.023	3.292TyrLeu: 3.292 ± 0.027	0.702TyrMet: 0.702 ± 0.012	1.908TyrAsn: 1.908 ± 0.021	1.377TyrPro: 1.377 ± 0.021	1.11TyrGln: 1.11 ± 0.015	1.659TyrArg: 1.659 ± 0.019	2.745TyrSer: 2.745 ± 0.023	1.819TyrThr: 1.819 ± 0.019	2.099TyrVal: 2.099 ± 0.024	0.463TyrTrp: 0.463 ± 0.01	1.464TyrTyr: 1.464 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 14651 proteins (5034946 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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