Amino acid dipepetide frequency for Tortoise microvirus 67

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.388AlaAla: 8.388 ± 2.982
0.599AlaCys: 0.599 ± 0.413
4.194AlaAsp: 4.194 ± 2.104
4.793AlaGlu: 4.793 ± 1.164
4.793AlaPhe: 4.793 ± 2.272
5.992AlaGly: 5.992 ± 2.169
2.397AlaHis: 2.397 ± 1.158
1.797AlaIle: 1.797 ± 1.509
4.793AlaLys: 4.793 ± 2.865
6.591AlaLeu: 6.591 ± 1.952
1.198AlaMet: 1.198 ± 1.106
2.996AlaAsn: 2.996 ± 0.723
7.789AlaPro: 7.789 ± 1.716
3.595AlaGln: 3.595 ± 1.187
4.194AlaArg: 4.194 ± 1.347
7.789AlaSer: 7.789 ± 1.592
2.397AlaThr: 2.397 ± 1.302
4.793AlaVal: 4.793 ± 1.68
0.599AlaTrp: 0.599 ± 0.413
3.595AlaTyr: 3.595 ± 1.335
0.0AlaXaa: 0.0 ± 0.0
Cys
0.599CysAla: 0.599 ± 0.648
0.599CysCys: 0.599 ± 0.837
1.797CysAsp: 1.797 ± 1.156
1.198CysGlu: 1.198 ± 0.832
0.599CysPhe: 0.599 ± 0.837
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.397CysIle: 2.397 ± 0.966
0.0CysLys: 0.0 ± 0.0
1.198CysLeu: 1.198 ± 0.577
0.599CysMet: 0.599 ± 0.701
1.797CysAsn: 1.797 ± 0.954
0.0CysPro: 0.0 ± 0.0
0.599CysGln: 0.599 ± 0.648
1.797CysArg: 1.797 ± 1.441
0.599CysSer: 0.599 ± 0.721
0.599CysThr: 0.599 ± 0.413
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.198CysTyr: 1.198 ± 0.928
0.0CysXaa: 0.0 ± 0.0
Asp
7.789AspAla: 7.789 ± 1.45
1.797AspCys: 1.797 ± 0.771
2.996AspAsp: 2.996 ± 0.935
2.996AspGlu: 2.996 ± 1.413
4.793AspPhe: 4.793 ± 1.185
1.797AspGly: 1.797 ± 1.28
0.0AspHis: 0.0 ± 0.0
2.397AspIle: 2.397 ± 0.831
3.595AspLys: 3.595 ± 1.543
5.392AspLeu: 5.392 ± 2.215
0.599AspMet: 0.599 ± 0.413
1.198AspAsn: 1.198 ± 0.948
2.996AspPro: 2.996 ± 0.531
0.599AspGln: 0.599 ± 0.648
2.397AspArg: 2.397 ± 1.081
4.194AspSer: 4.194 ± 1.565
3.595AspThr: 3.595 ± 1.872
4.194AspVal: 4.194 ± 0.962
1.198AspTrp: 1.198 ± 1.061
4.194AspTyr: 4.194 ± 1.149
0.0AspXaa: 0.0 ± 0.0
Glu
2.397GluAla: 2.397 ± 0.712
1.797GluCys: 1.797 ± 1.011
2.397GluAsp: 2.397 ± 2.213
1.198GluGlu: 1.198 ± 0.541
4.194GluPhe: 4.194 ± 0.887
2.397GluGly: 2.397 ± 0.951
0.599GluHis: 0.599 ± 0.553
4.194GluIle: 4.194 ± 1.968
1.797GluLys: 1.797 ± 1.161
6.591GluLeu: 6.591 ± 1.887
1.198GluMet: 1.198 ± 1.301
1.198GluAsn: 1.198 ± 0.826
0.0GluPro: 0.0 ± 0.0
2.996GluGln: 2.996 ± 2.052
1.797GluArg: 1.797 ± 1.156
2.397GluSer: 2.397 ± 0.891
1.797GluThr: 1.797 ± 1.016
5.392GluVal: 5.392 ± 2.483
0.0GluTrp: 0.0 ± 0.0
5.392GluTyr: 5.392 ± 0.755
0.0GluXaa: 0.0 ± 0.0
Phe
3.595PheAla: 3.595 ± 1.189
0.599PheCys: 0.599 ± 0.648
5.392PheAsp: 5.392 ± 2.133
0.0PheGlu: 0.0 ± 0.0
4.793PhePhe: 4.793 ± 2.716
4.793PheGly: 4.793 ± 0.747
1.198PheHis: 1.198 ± 0.577
4.793PheIle: 4.793 ± 1.465
2.397PheLys: 2.397 ± 1.341
2.996PheLeu: 2.996 ± 1.548
3.595PheMet: 3.595 ± 1.687
1.797PheAsn: 1.797 ± 1.239
4.793PhePro: 4.793 ± 1.663
2.397PheGln: 2.397 ± 2.213
2.996PheArg: 2.996 ± 1.453
4.194PheSer: 4.194 ± 1.489
3.595PheThr: 3.595 ± 1.544
2.397PheVal: 2.397 ± 0.667
0.0PheTrp: 0.0 ± 0.0
2.996PheTyr: 2.996 ± 1.579
0.0PheXaa: 0.0 ± 0.0
Gly
5.992GlyAla: 5.992 ± 1.352
0.599GlyCys: 0.599 ± 0.681
3.595GlyAsp: 3.595 ± 0.901
4.194GlyGlu: 4.194 ± 2.231
2.397GlyPhe: 2.397 ± 1.804
5.992GlyGly: 5.992 ± 1.908
2.996GlyHis: 2.996 ± 1.359
1.797GlyIle: 1.797 ± 0.785
3.595GlyLys: 3.595 ± 1.732
3.595GlyLeu: 3.595 ± 1.212
2.397GlyMet: 2.397 ± 1.532
0.599GlyAsn: 0.599 ± 0.413
0.599GlyPro: 0.599 ± 0.413
2.397GlyGln: 2.397 ± 1.54
3.595GlyArg: 3.595 ± 1.257
11.384GlySer: 11.384 ± 3.531
4.793GlyThr: 4.793 ± 2.716
4.793GlyVal: 4.793 ± 2.028
1.198GlyTrp: 1.198 ± 0.577
2.397GlyTyr: 2.397 ± 1.216
0.0GlyXaa: 0.0 ± 0.0
His
1.198HisAla: 1.198 ± 0.948
2.996HisCys: 2.996 ± 1.708
0.0HisAsp: 0.0 ± 0.0
1.198HisGlu: 1.198 ± 1.106
0.599HisPhe: 0.599 ± 0.648
1.797HisGly: 1.797 ± 0.423
0.0HisHis: 0.0 ± 0.0
0.599HisIle: 0.599 ± 0.721
0.599HisLys: 0.599 ± 0.648
1.797HisLeu: 1.797 ± 1.15
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.599HisArg: 0.599 ± 0.648
1.797HisSer: 1.797 ± 0.423
0.599HisThr: 0.599 ± 0.413
1.198HisVal: 1.198 ± 0.69
0.0HisTrp: 0.0 ± 0.0
1.198HisTyr: 1.198 ± 0.577
0.0HisXaa: 0.0 ± 0.0
Ile
5.392IleAla: 5.392 ± 1.332
0.0IleCys: 0.0 ± 0.0
2.996IleAsp: 2.996 ± 0.991
1.198IleGlu: 1.198 ± 0.541
1.198IlePhe: 1.198 ± 0.541
5.992IleGly: 5.992 ± 2.219
0.599IleHis: 0.599 ± 0.413
0.0IleIle: 0.0 ± 0.0
1.198IleLys: 1.198 ± 0.845
4.194IleLeu: 4.194 ± 1.433
1.198IleMet: 1.198 ± 1.191
1.797IleAsn: 1.797 ± 1.078
4.793IlePro: 4.793 ± 1.827
2.996IleGln: 2.996 ± 2.175
5.992IleArg: 5.992 ± 2.411
3.595IleSer: 3.595 ± 0.754
2.996IleThr: 2.996 ± 1.064
0.0IleVal: 0.0 ± 0.0
0.599IleTrp: 0.599 ± 0.413
1.198IleTyr: 1.198 ± 0.996
0.0IleXaa: 0.0 ± 0.0
Lys
4.194LysAla: 4.194 ± 2.141
0.0LysCys: 0.0 ± 0.0
3.595LysAsp: 3.595 ± 1.371
3.595LysGlu: 3.595 ± 1.657
1.198LysPhe: 1.198 ± 1.055
1.797LysGly: 1.797 ± 1.944
0.0LysHis: 0.0 ± 0.0
2.397LysIle: 2.397 ± 1.01
0.599LysLys: 0.599 ± 0.648
2.397LysLeu: 2.397 ± 1.154
2.397LysMet: 2.397 ± 0.96
0.599LysAsn: 0.599 ± 0.648
1.797LysPro: 1.797 ± 0.929
2.996LysGln: 2.996 ± 1.043
1.797LysArg: 1.797 ± 1.045
4.194LysSer: 4.194 ± 1.553
1.198LysThr: 1.198 ± 0.541
0.599LysVal: 0.599 ± 0.681
0.599LysTrp: 0.599 ± 0.553
2.397LysTyr: 2.397 ± 1.367
0.0LysXaa: 0.0 ± 0.0
Leu
10.186LeuAla: 10.186 ± 1.827
1.797LeuCys: 1.797 ± 1.689
3.595LeuAsp: 3.595 ± 0.995
4.793LeuGlu: 4.793 ± 1.423
5.992LeuPhe: 5.992 ± 2.013
7.789LeuGly: 7.789 ± 1.831
1.797LeuHis: 1.797 ± 0.771
2.996LeuIle: 2.996 ± 0.813
2.397LeuLys: 2.397 ± 1.703
1.797LeuLeu: 1.797 ± 1.092
2.996LeuMet: 2.996 ± 0.719
5.392LeuAsn: 5.392 ± 1.534
4.793LeuPro: 4.793 ± 1.485
2.996LeuGln: 2.996 ± 1.064
3.595LeuArg: 3.595 ± 1.115
8.987LeuSer: 8.987 ± 2.669
4.194LeuThr: 4.194 ± 0.773
4.793LeuVal: 4.793 ± 1.362
0.599LeuTrp: 0.599 ± 0.648
1.198LeuTyr: 1.198 ± 0.826
0.0LeuXaa: 0.0 ± 0.0
Met
2.397MetAla: 2.397 ± 0.798
0.0MetCys: 0.0 ± 0.0
0.599MetAsp: 0.599 ± 0.553
0.599MetGlu: 0.599 ± 0.553
1.797MetPhe: 1.797 ± 1.239
1.198MetGly: 1.198 ± 0.541
0.0MetHis: 0.0 ± 0.0
2.397MetIle: 2.397 ± 1.105
0.0MetLys: 0.0 ± 0.0
1.797MetLeu: 1.797 ± 0.711
0.0MetMet: 0.0 ± 0.0
0.599MetAsn: 0.599 ± 0.837
1.797MetPro: 1.797 ± 0.767
1.198MetGln: 1.198 ± 0.893
1.797MetArg: 1.797 ± 1.944
2.397MetSer: 2.397 ± 1.782
2.996MetThr: 2.996 ± 0.952
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.797MetTyr: 1.797 ± 0.767
0.0MetXaa: 0.0 ± 0.0
Asn
1.797AsnAla: 1.797 ± 1.013
0.599AsnCys: 0.599 ± 0.648
0.599AsnAsp: 0.599 ± 0.413
2.996AsnGlu: 2.996 ± 1.209
6.591AsnPhe: 6.591 ± 1.034
2.996AsnGly: 2.996 ± 1.572
0.0AsnHis: 0.0 ± 0.0
2.397AsnIle: 2.397 ± 0.972
1.797AsnLys: 1.797 ± 1.66
5.992AsnLeu: 5.992 ± 1.05
0.0AsnMet: 0.0 ± 0.0
2.397AsnAsn: 2.397 ± 1.083
1.797AsnPro: 1.797 ± 0.787
1.198AsnGln: 1.198 ± 1.675
1.797AsnArg: 1.797 ± 1.011
1.198AsnSer: 1.198 ± 1.055
3.595AsnThr: 3.595 ± 1.911
1.797AsnVal: 1.797 ± 0.711
1.198AsnTrp: 1.198 ± 0.671
2.397AsnTyr: 2.397 ± 0.951
0.0AsnXaa: 0.0 ± 0.0
Pro
1.198ProAla: 1.198 ± 0.826
1.198ProCys: 1.198 ± 0.577
4.194ProAsp: 4.194 ± 1.565
1.198ProGlu: 1.198 ± 0.69
4.194ProPhe: 4.194 ± 2.273
1.797ProGly: 1.797 ± 0.929
1.198ProHis: 1.198 ± 0.948
2.397ProIle: 2.397 ± 1.652
0.599ProLys: 0.599 ± 0.681
3.595ProLeu: 3.595 ± 0.707
0.599ProMet: 0.599 ± 0.413
2.397ProAsn: 2.397 ± 0.638
2.397ProPro: 2.397 ± 0.638
1.797ProGln: 1.797 ± 0.787
2.397ProArg: 2.397 ± 1.085
5.392ProSer: 5.392 ± 0.912
5.392ProThr: 5.392 ± 1.656
6.591ProVal: 6.591 ± 2.579
0.0ProTrp: 0.0 ± 0.0
2.397ProTyr: 2.397 ± 0.799
0.0ProXaa: 0.0 ± 0.0
Gln
1.198GlnAla: 1.198 ± 1.106
0.0GlnCys: 0.0 ± 0.0
2.397GlnAsp: 2.397 ± 0.798
3.595GlnGlu: 3.595 ± 1.868
1.198GlnPhe: 1.198 ± 0.577
2.996GlnGly: 2.996 ± 1.573
0.599GlnHis: 0.599 ± 0.681
3.595GlnIle: 3.595 ± 2.09
1.198GlnLys: 1.198 ± 1.106
1.797GlnLeu: 1.797 ± 0.776
1.198GlnMet: 1.198 ± 0.671
2.397GlnAsn: 2.397 ± 1.54
1.198GlnPro: 1.198 ± 0.541
4.194GlnGln: 4.194 ± 3.41
4.194GlnArg: 4.194 ± 1.67
4.194GlnSer: 4.194 ± 1.809
2.996GlnThr: 2.996 ± 1.162
1.198GlnVal: 1.198 ± 0.832
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.194ArgAla: 4.194 ± 1.387
0.0ArgCys: 0.0 ± 0.0
2.397ArgAsp: 2.397 ± 1.19
3.595ArgGlu: 3.595 ± 1.706
3.595ArgPhe: 3.595 ± 1.437
3.595ArgGly: 3.595 ± 1.235
1.198ArgHis: 1.198 ± 1.296
2.397ArgIle: 2.397 ± 1.135
2.397ArgLys: 2.397 ± 1.352
7.789ArgLeu: 7.789 ± 1.702
1.198ArgMet: 1.198 ± 0.577
5.392ArgAsn: 5.392 ± 1.12
4.194ArgPro: 4.194 ± 3.076
0.599ArgGln: 0.599 ± 0.413
5.392ArgArg: 5.392 ± 1.177
4.194ArgSer: 4.194 ± 1.699
1.198ArgThr: 1.198 ± 0.577
3.595ArgVal: 3.595 ± 1.781
0.0ArgTrp: 0.0 ± 0.0
3.595ArgTyr: 3.595 ± 1.823
0.0ArgXaa: 0.0 ± 0.0
Ser
6.591SerAla: 6.591 ± 1.75
1.198SerCys: 1.198 ± 1.296
3.595SerAsp: 3.595 ± 0.754
3.595SerGlu: 3.595 ± 1.115
6.591SerPhe: 6.591 ± 1.75
7.19SerGly: 7.19 ± 2.036
1.797SerHis: 1.797 ± 0.423
2.397SerIle: 2.397 ± 1.19
5.992SerLys: 5.992 ± 1.905
9.587SerLeu: 9.587 ± 1.193
1.198SerMet: 1.198 ± 0.826
4.793SerAsn: 4.793 ± 0.747
4.793SerPro: 4.793 ± 1.965
4.194SerGln: 4.194 ± 1.225
5.392SerArg: 5.392 ± 2.058
9.587SerSer: 9.587 ± 3.068
2.996SerThr: 2.996 ± 1.407
8.388SerVal: 8.388 ± 2.614
0.599SerTrp: 0.599 ± 0.413
2.397SerTyr: 2.397 ± 1.367
0.0SerXaa: 0.0 ± 0.0
Thr
4.793ThrAla: 4.793 ± 2.272
0.0ThrCys: 0.0 ± 0.0
4.793ThrAsp: 4.793 ± 1.456
2.996ThrGlu: 2.996 ± 0.813
2.397ThrPhe: 2.397 ± 1.302
3.595ThrGly: 3.595 ± 1.179
0.0ThrHis: 0.0 ± 0.0
2.397ThrIle: 2.397 ± 1.216
0.599ThrLys: 0.599 ± 0.648
7.789ThrLeu: 7.789 ± 2.072
1.198ThrMet: 1.198 ± 0.671
1.198ThrAsn: 1.198 ± 0.577
1.797ThrPro: 1.797 ± 1.28
2.397ThrGln: 2.397 ± 1.081
3.595ThrArg: 3.595 ± 1.622
6.591ThrSer: 6.591 ± 2.056
2.397ThrThr: 2.397 ± 1.135
2.996ThrVal: 2.996 ± 1.456
0.0ThrTrp: 0.0 ± 0.0
2.397ThrTyr: 2.397 ± 1.088
0.0ThrXaa: 0.0 ± 0.0
Val
6.591ValAla: 6.591 ± 1.571
0.599ValCys: 0.599 ± 0.837
3.595ValAsp: 3.595 ± 0.901
4.194ValGlu: 4.194 ± 0.721
1.797ValPhe: 1.797 ± 0.771
4.194ValGly: 4.194 ± 1.973
0.599ValHis: 0.599 ± 0.648
1.797ValIle: 1.797 ± 1.165
2.397ValLys: 2.397 ± 0.831
2.996ValLeu: 2.996 ± 0.701
1.198ValMet: 1.198 ± 0.985
2.996ValAsn: 2.996 ± 0.991
3.595ValPro: 3.595 ± 0.875
1.198ValGln: 1.198 ± 0.664
2.397ValArg: 2.397 ± 1.07
5.992ValSer: 5.992 ± 1.217
4.793ValThr: 4.793 ± 1.419
1.797ValVal: 1.797 ± 0.898
0.599ValTrp: 0.599 ± 0.553
3.595ValTyr: 3.595 ± 1.129
0.0ValXaa: 0.0 ± 0.0
Trp
0.599TrpAla: 0.599 ± 0.413
0.0TrpCys: 0.0 ± 0.0
0.599TrpAsp: 0.599 ± 0.413
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.599TrpHis: 0.599 ± 0.553
0.599TrpIle: 0.599 ± 0.648
0.0TrpLys: 0.0 ± 0.0
1.198TrpLeu: 1.198 ± 1.296
0.0TrpMet: 0.0 ± 0.0
1.797TrpAsn: 1.797 ± 1.377
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.198TrpArg: 1.198 ± 0.577
0.599TrpSer: 0.599 ± 0.413
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.194TyrAla: 4.194 ± 1.018
1.198TyrCys: 1.198 ± 0.832
5.392TyrAsp: 5.392 ± 2.295
1.797TyrGlu: 1.797 ± 0.947
0.599TyrPhe: 0.599 ± 0.648
2.996TyrGly: 2.996 ± 0.762
0.599TyrHis: 0.599 ± 0.648
4.793TyrIle: 4.793 ± 1.599
2.397TyrLys: 2.397 ± 0.799
3.595TyrLeu: 3.595 ± 1.349
0.0TyrMet: 0.0 ± 0.0
1.797TyrAsn: 1.797 ± 1.377
1.797TyrPro: 1.797 ± 0.922
1.797TyrGln: 1.797 ± 0.787
3.595TyrArg: 3.595 ± 1.961
3.595TyrSer: 3.595 ± 1.844
1.797TyrThr: 1.797 ± 0.767
2.397TyrVal: 2.397 ± 1.366
0.0TyrTrp: 0.0 ± 0.0
5.992TyrTyr: 5.992 ± 0.861
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1670 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski