Amino acid dipepetide frequency for Hemidesmus yellow mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.471AlaAla: 2.471 ± 1.438
1.647AlaCys: 1.647 ± 0.98
1.647AlaAsp: 1.647 ± 0.988
0.824AlaGlu: 0.824 ± 0.868
0.824AlaPhe: 0.824 ± 0.901
0.824AlaGly: 0.824 ± 0.601
0.824AlaHis: 0.824 ± 0.641
3.295AlaIle: 3.295 ± 1.23
4.942AlaLys: 4.942 ± 1.73
5.766AlaLeu: 5.766 ± 1.168
0.824AlaMet: 0.824 ± 0.868
0.824AlaAsn: 0.824 ± 0.891
3.295AlaPro: 3.295 ± 2.243
2.471AlaGln: 2.471 ± 1.645
4.942AlaArg: 4.942 ± 1.518
4.119AlaSer: 4.119 ± 1.675
3.295AlaThr: 3.295 ± 1.823
3.295AlaVal: 3.295 ± 1.47
1.647AlaTrp: 1.647 ± 1.202
1.647AlaTyr: 1.647 ± 0.874
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
3.295CysCys: 3.295 ± 2.585
0.824CysAsp: 0.824 ± 0.866
0.824CysGlu: 0.824 ± 0.641
1.647CysPhe: 1.647 ± 1.68
1.647CysGly: 1.647 ± 0.938
0.0CysHis: 0.0 ± 0.0
1.647CysIle: 1.647 ± 0.725
2.471CysLys: 2.471 ± 1.167
0.824CysLeu: 0.824 ± 0.891
0.0CysMet: 0.0 ± 0.0
1.647CysAsn: 1.647 ± 0.938
1.647CysPro: 1.647 ± 1.736
0.824CysGln: 0.824 ± 0.901
0.824CysArg: 0.824 ± 0.601
3.295CysSer: 3.295 ± 1.26
2.471CysThr: 2.471 ± 0.865
1.647CysVal: 1.647 ± 0.914
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.647AspAla: 1.647 ± 0.874
0.824AspCys: 0.824 ± 0.901
1.647AspAsp: 1.647 ± 1.202
2.471AspGlu: 2.471 ± 1.802
0.824AspPhe: 0.824 ± 0.641
1.647AspGly: 1.647 ± 0.885
0.824AspHis: 0.824 ± 0.901
4.942AspIle: 4.942 ± 2.516
0.824AspLys: 0.824 ± 0.641
6.59AspLeu: 6.59 ± 1.686
0.0AspMet: 0.0 ± 0.0
2.471AspAsn: 2.471 ± 1.258
1.647AspPro: 1.647 ± 0.938
0.824AspGln: 0.824 ± 0.601
3.295AspArg: 3.295 ± 1.451
5.766AspSer: 5.766 ± 2.396
1.647AspThr: 1.647 ± 0.91
5.766AspVal: 5.766 ± 1.508
1.647AspTrp: 1.647 ± 1.202
1.647AspTyr: 1.647 ± 0.835
0.0AspXaa: 0.0 ± 0.0
Glu
4.119GluAla: 4.119 ± 2.337
0.0GluCys: 0.0 ± 0.0
2.471GluAsp: 2.471 ± 1.085
4.119GluGlu: 4.119 ± 3.004
2.471GluPhe: 2.471 ± 1.802
3.295GluGly: 3.295 ± 1.144
2.471GluHis: 2.471 ± 1.955
2.471GluIle: 2.471 ± 1.188
0.824GluLys: 0.824 ± 0.601
4.942GluLeu: 4.942 ± 2.079
0.0GluMet: 0.0 ± 0.0
5.766GluAsn: 5.766 ± 1.478
2.471GluPro: 2.471 ± 0.815
2.471GluGln: 2.471 ± 1.23
1.647GluArg: 1.647 ± 0.874
1.647GluSer: 1.647 ± 1.229
2.471GluThr: 2.471 ± 1.164
3.295GluVal: 3.295 ± 1.78
1.647GluTrp: 1.647 ± 0.938
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.824PheCys: 0.824 ± 0.641
3.295PheAsp: 3.295 ± 1.709
1.647PheGlu: 1.647 ± 0.725
0.824PhePhe: 0.824 ± 0.601
1.647PheGly: 1.647 ± 1.282
2.471PheHis: 2.471 ± 1.259
2.471PheIle: 2.471 ± 0.99
2.471PheLys: 2.471 ± 1.085
6.59PheLeu: 6.59 ± 2.368
0.824PheMet: 0.824 ± 0.601
3.295PheAsn: 3.295 ± 1.962
0.824PhePro: 0.824 ± 0.866
4.942PheGln: 4.942 ± 2.258
4.119PheArg: 4.119 ± 1.529
3.295PheSer: 3.295 ± 1.709
4.119PheThr: 4.119 ± 1.531
0.0PheVal: 0.0 ± 0.0
1.647PheTrp: 1.647 ± 1.282
1.647PheTyr: 1.647 ± 0.97
0.0PheXaa: 0.0 ± 0.0
Gly
0.824GlyAla: 0.824 ± 0.601
1.647GlyCys: 1.647 ± 0.97
4.942GlyAsp: 4.942 ± 2.124
2.471GlyGlu: 2.471 ± 1.188
0.824GlyPhe: 0.824 ± 0.901
4.942GlyGly: 4.942 ± 1.804
0.824GlyHis: 0.824 ± 0.601
3.295GlyIle: 3.295 ± 0.909
5.766GlyLys: 5.766 ± 2.554
0.0GlyLeu: 0.0 ± 0.0
0.0GlyMet: 0.0 ± 0.0
1.647GlyAsn: 1.647 ± 1.211
2.471GlyPro: 2.471 ± 1.167
3.295GlyGln: 3.295 ± 1.331
2.471GlyArg: 2.471 ± 1.259
4.119GlySer: 4.119 ± 1.579
0.824GlyThr: 0.824 ± 0.601
3.295GlyVal: 3.295 ± 1.962
0.0GlyTrp: 0.0 ± 0.0
0.824GlyTyr: 0.824 ± 0.866
0.0GlyXaa: 0.0 ± 0.0
His
0.824HisAla: 0.824 ± 0.641
2.471HisCys: 2.471 ± 2.116
1.647HisAsp: 1.647 ± 0.988
0.824HisGlu: 0.824 ± 0.601
1.647HisPhe: 1.647 ± 0.835
0.0HisGly: 0.0 ± 0.0
4.119HisHis: 4.119 ± 3.57
1.647HisIle: 1.647 ± 1.211
2.471HisLys: 2.471 ± 1.496
1.647HisLeu: 1.647 ± 1.202
0.824HisMet: 0.824 ± 0.776
2.471HisAsn: 2.471 ± 1.188
4.119HisPro: 4.119 ± 1.735
1.647HisGln: 1.647 ± 0.97
3.295HisArg: 3.295 ± 1.939
4.942HisSer: 4.942 ± 1.982
2.471HisThr: 2.471 ± 1.923
0.824HisVal: 0.824 ± 0.601
0.0HisTrp: 0.0 ± 0.0
0.824HisTyr: 0.824 ± 0.601
0.0HisXaa: 0.0 ± 0.0
Ile
0.824IleAla: 0.824 ± 0.641
4.119IleCys: 4.119 ± 1.131
2.471IleAsp: 2.471 ± 0.99
0.824IleGlu: 0.824 ± 0.601
2.471IlePhe: 2.471 ± 1.293
3.295IleGly: 3.295 ± 1.239
1.647IleHis: 1.647 ± 1.131
2.471IleIle: 2.471 ± 0.849
4.942IleLys: 4.942 ± 1.34
1.647IleLeu: 1.647 ± 1.211
0.0IleMet: 0.0 ± 0.0
2.471IleAsn: 2.471 ± 0.849
2.471IlePro: 2.471 ± 1.24
5.766IleGln: 5.766 ± 3.134
4.119IleArg: 4.119 ± 1.053
6.59IleSer: 6.59 ± 1.908
4.942IleThr: 4.942 ± 2.438
2.471IleVal: 2.471 ± 0.926
1.647IleTrp: 1.647 ± 0.988
1.647IleTyr: 1.647 ± 0.98
0.0IleXaa: 0.0 ± 0.0
Lys
3.295LysAla: 3.295 ± 1.248
0.824LysCys: 0.824 ± 0.84
1.647LysAsp: 1.647 ± 1.202
4.942LysGlu: 4.942 ± 1.435
1.647LysPhe: 1.647 ± 0.988
0.0LysGly: 0.0 ± 0.0
0.824LysHis: 0.824 ± 0.601
4.119LysIle: 4.119 ± 1.925
2.471LysLys: 2.471 ± 1.759
0.824LysLeu: 0.824 ± 0.868
0.0LysMet: 0.0 ± 0.0
6.59LysAsn: 6.59 ± 1.782
1.647LysPro: 1.647 ± 0.725
0.824LysGln: 0.824 ± 0.601
4.942LysArg: 4.942 ± 1.133
8.237LysSer: 8.237 ± 1.36
0.824LysThr: 0.824 ± 0.601
4.942LysVal: 4.942 ± 2.311
0.0LysTrp: 0.0 ± 0.0
4.119LysTyr: 4.119 ± 1.577
0.0LysXaa: 0.0 ± 0.0
Leu
2.471LeuAla: 2.471 ± 1.544
1.647LeuCys: 1.647 ± 1.202
4.942LeuAsp: 4.942 ± 1.967
2.471LeuGlu: 2.471 ± 1.121
4.119LeuPhe: 4.119 ± 1.807
3.295LeuGly: 3.295 ± 1.578
3.295LeuHis: 3.295 ± 1.709
4.942LeuIle: 4.942 ± 3.363
4.942LeuLys: 4.942 ± 1.424
5.766LeuLeu: 5.766 ± 2.289
0.824LeuMet: 0.824 ± 0.601
2.471LeuAsn: 2.471 ± 0.865
4.119LeuPro: 4.119 ± 1.419
4.119LeuGln: 4.119 ± 1.634
7.414LeuArg: 7.414 ± 3.426
5.766LeuSer: 5.766 ± 1.907
4.119LeuThr: 4.119 ± 1.73
3.295LeuVal: 3.295 ± 1.573
0.824LeuTrp: 0.824 ± 0.601
3.295LeuTyr: 3.295 ± 2.517
0.0LeuXaa: 0.0 ± 0.0
Met
0.824MetAla: 0.824 ± 0.641
0.824MetCys: 0.824 ± 0.891
3.295MetAsp: 3.295 ± 1.459
0.0MetGlu: 0.0 ± 0.0
3.295MetPhe: 3.295 ± 1.437
1.647MetGly: 1.647 ± 0.874
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.824MetLeu: 0.824 ± 0.868
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.295MetPro: 3.295 ± 1.261
0.0MetGln: 0.0 ± 0.0
0.824MetArg: 0.824 ± 0.891
0.824MetSer: 0.824 ± 0.641
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.647MetTyr: 1.647 ± 1.282
0.0MetXaa: 0.0 ± 0.0
Asn
4.119AsnAla: 4.119 ± 1.572
0.824AsnCys: 0.824 ± 0.601
2.471AsnAsp: 2.471 ± 0.926
0.824AsnGlu: 0.824 ± 0.641
1.647AsnPhe: 1.647 ± 0.725
1.647AsnGly: 1.647 ± 0.885
4.942AsnHis: 4.942 ± 2.436
2.471AsnIle: 2.471 ± 1.167
0.824AsnLys: 0.824 ± 0.601
7.414AsnLeu: 7.414 ± 2.719
2.471AsnMet: 2.471 ± 1.243
1.647AsnAsn: 1.647 ± 0.725
2.471AsnPro: 2.471 ± 0.849
0.824AsnGln: 0.824 ± 0.601
0.0AsnArg: 0.0 ± 0.0
3.295AsnSer: 3.295 ± 1.303
2.471AsnThr: 2.471 ± 1.091
1.647AsnVal: 1.647 ± 1.202
0.0AsnTrp: 0.0 ± 0.0
4.119AsnTyr: 4.119 ± 1.182
0.0AsnXaa: 0.0 ± 0.0
Pro
2.471ProAla: 2.471 ± 0.865
3.295ProCys: 3.295 ± 1.406
3.295ProAsp: 3.295 ± 1.067
3.295ProGlu: 3.295 ± 1.445
1.647ProPhe: 1.647 ± 0.725
2.471ProGly: 2.471 ± 1.293
3.295ProHis: 3.295 ± 1.773
4.119ProIle: 4.119 ± 1.074
0.824ProLys: 0.824 ± 0.601
3.295ProLeu: 3.295 ± 1.133
0.824ProMet: 0.824 ± 0.641
0.824ProAsn: 0.824 ± 0.601
5.766ProPro: 5.766 ± 2.845
3.295ProGln: 3.295 ± 1.699
6.59ProArg: 6.59 ± 1.634
5.766ProSer: 5.766 ± 1.646
4.942ProThr: 4.942 ± 2.09
7.414ProVal: 7.414 ± 3.033
1.647ProTrp: 1.647 ± 0.98
1.647ProTyr: 1.647 ± 0.725
0.0ProXaa: 0.0 ± 0.0
Gln
4.942GlnAla: 4.942 ± 1.996
0.0GlnCys: 0.0 ± 0.0
1.647GlnAsp: 1.647 ± 1.343
6.59GlnGlu: 6.59 ± 1.841
1.647GlnPhe: 1.647 ± 0.835
0.0GlnGly: 0.0 ± 0.0
0.824GlnHis: 0.824 ± 0.901
0.824GlnIle: 0.824 ± 0.84
1.647GlnLys: 1.647 ± 1.292
2.471GlnLeu: 2.471 ± 1.085
0.824GlnMet: 0.824 ± 0.901
2.471GlnAsn: 2.471 ± 1.778
5.766GlnPro: 5.766 ± 2.732
1.647GlnGln: 1.647 ± 1.178
2.471GlnArg: 2.471 ± 1.167
3.295GlnSer: 3.295 ± 1.121
1.647GlnThr: 1.647 ± 1.26
5.766GlnVal: 5.766 ± 1.861
0.0GlnTrp: 0.0 ± 0.0
4.119GlnTyr: 4.119 ± 1.068
0.0GlnXaa: 0.0 ± 0.0
Arg
5.766ArgAla: 5.766 ± 1.668
1.647ArgCys: 1.647 ± 1.202
3.295ArgAsp: 3.295 ± 1.15
2.471ArgGlu: 2.471 ± 1.164
5.766ArgPhe: 5.766 ± 1.366
5.766ArgGly: 5.766 ± 1.634
5.766ArgHis: 5.766 ± 2.531
2.471ArgIle: 2.471 ± 0.874
2.471ArgLys: 2.471 ± 1.126
4.942ArgLeu: 4.942 ± 1.256
1.647ArgMet: 1.647 ± 0.98
0.824ArgAsn: 0.824 ± 0.601
6.59ArgPro: 6.59 ± 1.715
0.824ArgGln: 0.824 ± 0.868
7.414ArgArg: 7.414 ± 3.519
6.59ArgSer: 6.59 ± 1.74
4.119ArgThr: 4.119 ± 1.87
4.119ArgVal: 4.119 ± 1.283
0.0ArgTrp: 0.0 ± 0.0
1.647ArgTyr: 1.647 ± 0.914
0.0ArgXaa: 0.0 ± 0.0
Ser
4.942SerAla: 4.942 ± 2.437
0.824SerCys: 0.824 ± 0.601
4.119SerAsp: 4.119 ± 1.013
4.119SerGlu: 4.119 ± 1.886
4.942SerPhe: 4.942 ± 1.169
3.295SerGly: 3.295 ± 1.184
1.647SerHis: 1.647 ± 0.938
6.59SerIle: 6.59 ± 1.295
4.942SerLys: 4.942 ± 1.624
4.942SerLeu: 4.942 ± 2.039
1.647SerMet: 1.647 ± 1.234
5.766SerAsn: 5.766 ± 2.119
9.885SerPro: 9.885 ± 2.148
2.471SerGln: 2.471 ± 2.703
8.237SerArg: 8.237 ± 3.289
13.18SerSer: 13.18 ± 5.092
6.59SerThr: 6.59 ± 3.404
3.295SerVal: 3.295 ± 1.441
1.647SerTrp: 1.647 ± 0.98
2.471SerTyr: 2.471 ± 0.874
0.0SerXaa: 0.0 ± 0.0
Thr
4.119ThrAla: 4.119 ± 1.159
0.0ThrCys: 0.0 ± 0.0
0.0ThrAsp: 0.0 ± 0.0
4.119ThrGlu: 4.119 ± 1.159
0.824ThrPhe: 0.824 ± 0.891
4.119ThrGly: 4.119 ± 1.384
2.471ThrHis: 2.471 ± 1.375
3.295ThrIle: 3.295 ± 1.671
2.471ThrLys: 2.471 ± 1.274
4.119ThrLeu: 4.119 ± 1.577
0.824ThrMet: 0.824 ± 0.891
3.295ThrAsn: 3.295 ± 1.091
1.647ThrPro: 1.647 ± 1.064
3.295ThrGln: 3.295 ± 2.515
3.295ThrArg: 3.295 ± 1.573
7.414ThrSer: 7.414 ± 1.743
0.824ThrThr: 0.824 ± 0.891
2.471ThrVal: 2.471 ± 1.319
1.647ThrTrp: 1.647 ± 1.23
2.471ThrTyr: 2.471 ± 1.121
0.0ThrXaa: 0.0 ± 0.0
Val
1.647ValAla: 1.647 ± 1.064
0.824ValCys: 0.824 ± 0.601
1.647ValAsp: 1.647 ± 1.202
3.295ValGlu: 3.295 ± 1.785
5.766ValPhe: 5.766 ± 3.193
2.471ValGly: 2.471 ± 1.663
0.824ValHis: 0.824 ± 0.866
3.295ValIle: 3.295 ± 1.526
4.942ValLys: 4.942 ± 2.26
5.766ValLeu: 5.766 ± 1.657
1.647ValMet: 1.647 ± 0.932
0.0ValAsn: 0.0 ± 0.0
4.119ValPro: 4.119 ± 1.73
6.59ValGln: 6.59 ± 3.251
3.295ValArg: 3.295 ± 1.239
5.766ValSer: 5.766 ± 4.275
3.295ValThr: 3.295 ± 1.961
2.471ValVal: 2.471 ± 0.815
0.824ValTrp: 0.824 ± 0.84
3.295ValTyr: 3.295 ± 2.564
0.0ValXaa: 0.0 ± 0.0
Trp
1.647TrpAla: 1.647 ± 1.202
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.824TrpGlu: 0.824 ± 0.84
0.0TrpPhe: 0.0 ± 0.0
0.824TrpGly: 0.824 ± 0.601
0.824TrpHis: 0.824 ± 0.84
0.0TrpIle: 0.0 ± 0.0
0.824TrpLys: 0.824 ± 0.641
1.647TrpLeu: 1.647 ± 0.98
1.647TrpMet: 1.647 ± 1.282
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.824TrpGln: 0.824 ± 0.601
1.647TrpArg: 1.647 ± 1.178
0.824TrpSer: 0.824 ± 0.866
0.824TrpThr: 0.824 ± 0.84
1.647TrpVal: 1.647 ± 0.725
0.0TrpTrp: 0.0 ± 0.0
0.824TrpTyr: 0.824 ± 0.601
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.471TyrAla: 2.471 ± 1.319
0.0TyrCys: 0.0 ± 0.0
1.647TyrAsp: 1.647 ± 1.282
1.647TyrGlu: 1.647 ± 0.988
4.119TyrPhe: 4.119 ± 0.908
1.647TyrGly: 1.647 ± 0.938
0.824TyrHis: 0.824 ± 0.601
2.471TyrIle: 2.471 ± 1.167
1.647TyrLys: 1.647 ± 0.725
4.119TyrLeu: 4.119 ± 1.336
1.647TyrMet: 1.647 ± 0.982
2.471TyrAsn: 2.471 ± 1.167
2.471TyrPro: 2.471 ± 1.24
1.647TyrGln: 1.647 ± 0.98
3.295TyrArg: 3.295 ± 1.862
0.824TyrSer: 0.824 ± 0.866
0.824TyrThr: 0.824 ± 0.601
4.119TyrVal: 4.119 ± 1.17
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1215 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski