Amino acid dipepetide frequency for Candidatus Magnetoovum chiemensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.244AlaAla: 6.244 ± 0.085	0.876AlaCys: 0.876 ± 0.034	3.977AlaAsp: 3.977 ± 0.065	4.112AlaGlu: 4.112 ± 0.062	3.078AlaPhe: 3.078 ± 0.059	4.465AlaGly: 4.465 ± 0.088	1.328AlaHis: 1.328 ± 0.035	5.55AlaIle: 5.55 ± 0.078	4.95AlaLys: 4.95 ± 0.078	8.45AlaLeu: 8.45 ± 0.102	1.873AlaMet: 1.873 ± 0.042	2.795AlaAsn: 2.795 ± 0.052	2.092AlaPro: 2.092 ± 0.045	2.631AlaGln: 2.631 ± 0.058	2.686AlaArg: 2.686 ± 0.05	4.674AlaSer: 4.674 ± 0.076	2.678AlaThr: 2.678 ± 0.056	5.582AlaVal: 5.582 ± 0.08	0.58AlaTrp: 0.58 ± 0.023	2.437AlaTyr: 2.437 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	1.003CysAla: 1.003 ± 0.027	0.213CysCys: 0.213 ± 0.014	0.654CysAsp: 0.654 ± 0.025	0.62CysGlu: 0.62 ± 0.027	0.54CysPhe: 0.54 ± 0.024	0.995CysGly: 0.995 ± 0.04	0.29CysHis: 0.29 ± 0.02	0.866CysIle: 0.866 ± 0.028	0.782CysLys: 0.782 ± 0.028	1.125CysLeu: 1.125 ± 0.033	0.261CysMet: 0.261 ± 0.017	0.483CysAsn: 0.483 ± 0.02	0.632CysPro: 0.632 ± 0.026	0.3CysGln: 0.3 ± 0.016	0.526CysArg: 0.526 ± 0.026	0.902CysSer: 0.902 ± 0.034	0.543CysThr: 0.543 ± 0.027	0.661CysVal: 0.661 ± 0.021	0.126CysTrp: 0.126 ± 0.011	0.428CysTyr: 0.428 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	4.053AspAla: 4.053 ± 0.064	0.668AspCys: 0.668 ± 0.025	3.299AspAsp: 3.299 ± 0.068	4.069AspGlu: 4.069 ± 0.067	2.819AspPhe: 2.819 ± 0.052	3.413AspGly: 3.413 ± 0.064	0.745AspHis: 0.745 ± 0.03	6.008AspIle: 6.008 ± 0.093	4.989AspLys: 4.989 ± 0.08	4.796AspLeu: 4.796 ± 0.072	1.489AspMet: 1.489 ± 0.041	3.1AspAsn: 3.1 ± 0.055	1.678AspPro: 1.678 ± 0.041	1.004AspGln: 1.004 ± 0.03	2.426AspArg: 2.426 ± 0.048	3.11AspSer: 3.11 ± 0.048	3.077AspThr: 3.077 ± 0.059	3.523AspVal: 3.523 ± 0.057	0.546AspTrp: 0.546 ± 0.025	2.45AspTyr: 2.45 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.749GluAla: 4.749 ± 0.073	0.615GluCys: 0.615 ± 0.025	3.851GluAsp: 3.851 ± 0.067	4.555GluGlu: 4.555 ± 0.086	2.562GluPhe: 2.562 ± 0.05	3.594GluGly: 3.594 ± 0.071	1.284GluHis: 1.284 ± 0.035	6.434GluIle: 6.434 ± 0.101	5.611GluLys: 5.611 ± 0.083	7.121GluLeu: 7.121 ± 0.099	1.777GluMet: 1.777 ± 0.042	3.708GluAsn: 3.708 ± 0.067	2.018GluPro: 2.018 ± 0.044	2.389GluGln: 2.389 ± 0.049	3.315GluArg: 3.315 ± 0.062	3.067GluSer: 3.067 ± 0.053	3.928GluThr: 3.928 ± 0.056	3.367GluVal: 3.367 ± 0.063	0.471GluTrp: 0.471 ± 0.023	2.156GluTyr: 2.156 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	2.732PheAla: 2.732 ± 0.058	0.647PheCys: 0.647 ± 0.031	2.675PheAsp: 2.675 ± 0.051	2.382PheGlu: 2.382 ± 0.044	2.163PhePhe: 2.163 ± 0.057	2.494PheGly: 2.494 ± 0.05	0.705PheHis: 0.705 ± 0.029	4.123PheIle: 4.123 ± 0.079	3.191PheLys: 3.191 ± 0.059	4.317PheLeu: 4.317 ± 0.075	0.999PheMet: 0.999 ± 0.031	2.544PheAsn: 2.544 ± 0.051	1.399PhePro: 1.399 ± 0.038	1.083PheGln: 1.083 ± 0.036	1.609PheArg: 1.609 ± 0.039	3.172PheSer: 3.172 ± 0.069	2.515PheThr: 2.515 ± 0.056	2.434PheVal: 2.434 ± 0.049	0.393PheTrp: 0.393 ± 0.024	1.968PheTyr: 1.968 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	4.484GlyAla: 4.484 ± 0.069	0.867GlyCys: 0.867 ± 0.031	3.076GlyAsp: 3.076 ± 0.055	3.465GlyGlu: 3.465 ± 0.062	2.988GlyPhe: 2.988 ± 0.058	3.841GlyGly: 3.841 ± 0.073	1.142GlyHis: 1.142 ± 0.038	5.533GlyIle: 5.533 ± 0.078	4.701GlyLys: 4.701 ± 0.07	5.857GlyLeu: 5.857 ± 0.083	1.573GlyMet: 1.573 ± 0.042	2.405GlyAsn: 2.405 ± 0.056	1.264GlyPro: 1.264 ± 0.042	1.828GlyGln: 1.828 ± 0.047	2.704GlyArg: 2.704 ± 0.059	3.999GlySer: 3.999 ± 0.073	3.038GlyThr: 3.038 ± 0.066	3.824GlyVal: 3.824 ± 0.073	0.603GlyTrp: 0.603 ± 0.026	2.41GlyTyr: 2.41 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	0.993HisAla: 0.993 ± 0.034	0.251HisCys: 0.251 ± 0.015	0.86HisAsp: 0.86 ± 0.031	0.965HisGlu: 0.965 ± 0.036	0.792HisPhe: 0.792 ± 0.029	1.111HisGly: 1.111 ± 0.033	0.437HisHis: 0.437 ± 0.023	1.698HisIle: 1.698 ± 0.045	1.278HisLys: 1.278 ± 0.036	1.758HisLeu: 1.758 ± 0.041	0.243HisMet: 0.243 ± 0.013	0.86HisAsn: 0.86 ± 0.032	0.872HisPro: 0.872 ± 0.03	0.556HisGln: 0.556 ± 0.025	0.867HisArg: 0.867 ± 0.031	1.239HisSer: 1.239 ± 0.039	0.911HisThr: 0.911 ± 0.03	0.902HisVal: 0.902 ± 0.026	0.206HisTrp: 0.206 ± 0.014	0.704HisTyr: 0.704 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	6.621IleAla: 6.621 ± 0.089	0.927IleCys: 0.927 ± 0.032	5.582IleAsp: 5.582 ± 0.086	7.323IleGlu: 7.323 ± 0.105	3.378IlePhe: 3.378 ± 0.072	5.357IleGly: 5.357 ± 0.085	1.368IleHis: 1.368 ± 0.039	7.656IleIle: 7.656 ± 0.098	7.292IleLys: 7.292 ± 0.096	7.449IleLeu: 7.449 ± 0.083	1.883IleMet: 1.883 ± 0.045	5.262IleAsn: 5.262 ± 0.082	3.145IlePro: 3.145 ± 0.061	2.07IleGln: 2.07 ± 0.045	3.395IleArg: 3.395 ± 0.053	6.055IleSer: 6.055 ± 0.086	5.355IleThr: 5.355 ± 0.082	5.348IleVal: 5.348 ± 0.083	0.576IleTrp: 0.576 ± 0.025	2.937IleTyr: 2.937 ± 0.062	0.0IleXaa: 0.0 ± 0.0
Lys	5.302LysAla: 5.302 ± 0.078	0.7LysCys: 0.7 ± 0.029	5.301LysAsp: 5.301 ± 0.082	7.16LysGlu: 7.16 ± 0.095	2.22LysPhe: 2.22 ± 0.046	4.636LysGly: 4.636 ± 0.072	1.527LysHis: 1.527 ± 0.036	6.345LysIle: 6.345 ± 0.088	5.923LysLys: 5.923 ± 0.088	6.292LysLeu: 6.292 ± 0.079	1.837LysMet: 1.837 ± 0.042	4.219LysAsn: 4.219 ± 0.072	2.705LysPro: 2.705 ± 0.047	2.78LysGln: 2.78 ± 0.061	3.653LysArg: 3.653 ± 0.064	4.473LysSer: 4.473 ± 0.073	5.103LysThr: 5.103 ± 0.074	3.913LysVal: 3.913 ± 0.064	0.681LysTrp: 0.681 ± 0.029	2.765LysTyr: 2.765 ± 0.058	0.0LysXaa: 0.0 ± 0.0
Leu	6.283LeuAla: 6.283 ± 0.1	1.222LeuCys: 1.222 ± 0.037	5.183LeuAsp: 5.183 ± 0.065	6.039LeuGlu: 6.039 ± 0.081	4.373LeuPhe: 4.373 ± 0.075	5.514LeuGly: 5.514 ± 0.083	1.544LeuHis: 1.544 ± 0.038	8.408LeuIle: 8.408 ± 0.102	8.271LeuLys: 8.271 ± 0.089	8.908LeuLeu: 8.908 ± 0.113	2.362LeuMet: 2.362 ± 0.049	5.714LeuAsn: 5.714 ± 0.086	3.622LeuPro: 3.622 ± 0.065	2.517LeuGln: 2.517 ± 0.052	4.484LeuArg: 4.484 ± 0.076	7.939LeuSer: 7.939 ± 0.098	5.651LeuThr: 5.651 ± 0.08	4.694LeuVal: 4.694 ± 0.074	0.892LeuTrp: 0.892 ± 0.037	3.496LeuTyr: 3.496 ± 0.07	0.0LeuXaa: 0.0 ± 0.0
Met	1.821MetAla: 1.821 ± 0.04	0.211MetCys: 0.211 ± 0.014	1.366MetAsp: 1.366 ± 0.034	1.568MetGlu: 1.568 ± 0.038	1.028MetPhe: 1.028 ± 0.036	1.474MetGly: 1.474 ± 0.04	0.362MetHis: 0.362 ± 0.017	1.785MetIle: 1.785 ± 0.042	1.801MetLys: 1.801 ± 0.041	2.579MetLeu: 2.579 ± 0.054	0.551MetMet: 0.551 ± 0.028	1.169MetAsn: 1.169 ± 0.03	1.264MetPro: 1.264 ± 0.034	0.816MetGln: 0.816 ± 0.029	1.182MetArg: 1.182 ± 0.032	1.75MetSer: 1.75 ± 0.044	1.27MetThr: 1.27 ± 0.036	1.343MetVal: 1.343 ± 0.039	0.187MetTrp: 0.187 ± 0.012	0.606MetTyr: 0.606 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.584AsnAla: 3.584 ± 0.063	0.64AsnCys: 0.64 ± 0.027	3.017AsnAsp: 3.017 ± 0.058	3.308AsnGlu: 3.308 ± 0.074	1.932AsnPhe: 1.932 ± 0.052	2.973AsnGly: 2.973 ± 0.062	0.773AsnHis: 0.773 ± 0.027	5.353AsnIle: 5.353 ± 0.086	4.255AsnLys: 4.255 ± 0.073	4.626AsnLeu: 4.626 ± 0.069	1.206AsnMet: 1.206 ± 0.033	3.17AsnAsn: 3.17 ± 0.075	2.177AsnPro: 2.177 ± 0.049	1.23AsnGln: 1.23 ± 0.039	2.231AsnArg: 2.231 ± 0.047	3.359AsnSer: 3.359 ± 0.072	2.854AsnThr: 2.854 ± 0.054	3.01AsnVal: 3.01 ± 0.061	0.477AsnTrp: 0.477 ± 0.022	1.96AsnTyr: 1.96 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	2.29ProAla: 2.29 ± 0.044	0.421ProCys: 0.421 ± 0.021	2.291ProAsp: 2.291 ± 0.05	2.278ProGlu: 2.278 ± 0.045	1.829ProPhe: 1.829 ± 0.045	1.613ProGly: 1.613 ± 0.042	0.703ProHis: 0.703 ± 0.027	2.828ProIle: 2.828 ± 0.057	2.294ProLys: 2.294 ± 0.06	3.517ProLeu: 3.517 ± 0.06	0.823ProMet: 0.823 ± 0.026	1.602ProAsn: 1.602 ± 0.042	1.199ProPro: 1.199 ± 0.041	1.292ProGln: 1.292 ± 0.036	1.139ProArg: 1.139 ± 0.035	2.492ProSer: 2.492 ± 0.048	1.639ProThr: 1.639 ± 0.041	2.445ProVal: 2.445 ± 0.051	0.316ProTrp: 0.316 ± 0.019	1.486ProTyr: 1.486 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	2.181GlnAla: 2.181 ± 0.049	0.309GlnCys: 0.309 ± 0.015	1.493GlnAsp: 1.493 ± 0.037	2.124GlnGlu: 2.124 ± 0.048	1.061GlnPhe: 1.061 ± 0.033	1.683GlnGly: 1.683 ± 0.043	0.566GlnHis: 0.566 ± 0.021	2.551GlnIle: 2.551 ± 0.049	2.331GlnLys: 2.331 ± 0.06	2.628GlnLeu: 2.628 ± 0.057	0.843GlnMet: 0.843 ± 0.032	1.578GlnAsn: 1.578 ± 0.038	0.946GlnPro: 0.946 ± 0.033	1.181GlnGln: 1.181 ± 0.04	1.61GlnArg: 1.61 ± 0.039	1.979GlnSer: 1.979 ± 0.05	1.743GlnThr: 1.743 ± 0.045	1.478GlnVal: 1.478 ± 0.037	0.473GlnTrp: 0.473 ± 0.022	1.094GlnTyr: 1.094 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.91ArgAla: 2.91 ± 0.058	0.559ArgCys: 0.559 ± 0.026	2.259ArgAsp: 2.259 ± 0.045	2.733ArgGlu: 2.733 ± 0.055	2.124ArgPhe: 2.124 ± 0.04	2.334ArgGly: 2.334 ± 0.057	0.857ArgHis: 0.857 ± 0.033	3.74ArgIle: 3.74 ± 0.06	3.349ArgLys: 3.349 ± 0.054	4.78ArgLeu: 4.78 ± 0.074	1.09ArgMet: 1.09 ± 0.035	2.163ArgAsn: 2.163 ± 0.053	1.244ArgPro: 1.244 ± 0.039	1.865ArgGln: 1.865 ± 0.047	2.117ArgArg: 2.117 ± 0.055	2.399ArgSer: 2.399 ± 0.046	2.051ArgThr: 2.051 ± 0.048	2.462ArgVal: 2.462 ± 0.052	0.423ArgTrp: 0.423 ± 0.019	1.679ArgTyr: 1.679 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	5.116SerAla: 5.116 ± 0.089	0.801SerCys: 0.801 ± 0.026	3.763SerAsp: 3.763 ± 0.058	3.969SerGlu: 3.969 ± 0.063	3.199SerPhe: 3.199 ± 0.063	4.283SerGly: 4.283 ± 0.075	1.102SerHis: 1.102 ± 0.029	5.788SerIle: 5.788 ± 0.084	4.791SerLys: 4.791 ± 0.073	6.917SerLeu: 6.917 ± 0.088	1.559SerMet: 1.559 ± 0.038	3.219SerAsn: 3.219 ± 0.06	2.346SerPro: 2.346 ± 0.048	1.996SerGln: 1.996 ± 0.043	2.565SerArg: 2.565 ± 0.052	5.363SerSer: 5.363 ± 0.106	3.011SerThr: 3.011 ± 0.057	4.081SerVal: 4.081 ± 0.081	0.611SerTrp: 0.611 ± 0.026	2.394SerTyr: 2.394 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.512ThrAla: 4.512 ± 0.082	0.57ThrCys: 0.57 ± 0.024	2.901ThrAsp: 2.901 ± 0.053	3.047ThrGlu: 3.047 ± 0.055	2.257ThrPhe: 2.257 ± 0.045	3.738ThrGly: 3.738 ± 0.065	0.926ThrHis: 0.926 ± 0.031	5.136ThrIle: 5.136 ± 0.087	3.432ThrLys: 3.432 ± 0.052	5.521ThrLeu: 5.521 ± 0.077	1.173ThrMet: 1.173 ± 0.032	2.357ThrAsn: 2.357 ± 0.056	2.287ThrPro: 2.287 ± 0.051	1.512ThrGln: 1.512 ± 0.042	1.818ThrArg: 1.818 ± 0.046	3.448ThrSer: 3.448 ± 0.071	2.707ThrThr: 2.707 ± 0.064	3.785ThrVal: 3.785 ± 0.069	0.47ThrTrp: 0.47 ± 0.023	1.804ThrTyr: 1.804 ± 0.047	0.0ThrXaa: 0.0 ± 0.0
Val	3.38ValAla: 3.38 ± 0.07	0.828ValCys: 0.828 ± 0.028	2.997ValAsp: 2.997 ± 0.055	3.898ValGlu: 3.898 ± 0.062	3.09ValPhe: 3.09 ± 0.059	3.298ValGly: 3.298 ± 0.074	0.943ValHis: 0.943 ± 0.029	5.409ValIle: 5.409 ± 0.078	4.824ValLys: 4.824 ± 0.072	5.897ValLeu: 5.897 ± 0.086	1.518ValMet: 1.518 ± 0.041	3.152ValAsn: 3.152 ± 0.054	1.896ValPro: 1.896 ± 0.044	1.508ValGln: 1.508 ± 0.04	2.612ValArg: 2.612 ± 0.055	4.289ValSer: 4.289 ± 0.07	2.956ValThr: 2.956 ± 0.068	3.658ValVal: 3.658 ± 0.068	0.512ValTrp: 0.512 ± 0.023	2.292ValTyr: 2.292 ± 0.057	0.0ValXaa: 0.0 ± 0.0
Trp	0.562TrpAla: 0.562 ± 0.026	0.13TrpCys: 0.13 ± 0.012	0.528TrpAsp: 0.528 ± 0.028	0.511TrpGlu: 0.511 ± 0.025	0.398TrpPhe: 0.398 ± 0.021	0.519TrpGly: 0.519 ± 0.023	0.255TrpHis: 0.255 ± 0.016	0.771TrpIle: 0.771 ± 0.031	0.598TrpLys: 0.598 ± 0.026	0.979TrpLeu: 0.979 ± 0.038	0.217TrpMet: 0.217 ± 0.013	0.488TrpAsn: 0.488 ± 0.022	0.247TrpPro: 0.247 ± 0.017	0.41TrpGln: 0.41 ± 0.022	0.448TrpArg: 0.448 ± 0.019	0.596TrpSer: 0.596 ± 0.026	0.449TrpThr: 0.449 ± 0.021	0.507TrpVal: 0.507 ± 0.022	0.131TrpTrp: 0.131 ± 0.011	0.303TrpTyr: 0.303 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.238TyrAla: 2.238 ± 0.055	0.492TyrCys: 0.492 ± 0.022	2.188TyrAsp: 2.188 ± 0.05	2.447TyrGlu: 2.447 ± 0.052	1.713TyrPhe: 1.713 ± 0.047	2.267TyrGly: 2.267 ± 0.052	0.647TyrHis: 0.647 ± 0.026	2.995TyrIle: 2.995 ± 0.06	2.875TyrLys: 2.875 ± 0.055	3.601TyrLeu: 3.601 ± 0.065	0.858TyrMet: 0.858 ± 0.03	2.147TyrAsn: 2.147 ± 0.053	1.461TyrPro: 1.461 ± 0.038	0.888TyrGln: 0.888 ± 0.029	1.75TyrArg: 1.75 ± 0.041	2.568TyrSer: 2.568 ± 0.053	1.919TyrThr: 1.919 ± 0.047	1.939TyrVal: 1.939 ± 0.046	0.375TyrTrp: 0.375 ± 0.021	1.474TyrTyr: 1.474 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4107 proteins (1066827 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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