Amino acid dipepetide frequency for Hubei sobemo-like virus 11

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.353AlaAla: 2.353 ± 0.484
1.176AlaCys: 1.176 ± 0.681
3.529AlaAsp: 3.529 ± 3.495
4.706AlaGlu: 4.706 ± 2.814
5.882AlaPhe: 5.882 ± 3.403
3.529AlaGly: 3.529 ± 2.042
0.0AlaHis: 0.0 ± 0.0
2.353AlaIle: 2.353 ± 0.484
7.059AlaLys: 7.059 ± 2.239
10.588AlaLeu: 10.588 ± 0.589
1.176AlaMet: 1.176 ± 1.165
1.176AlaAsn: 1.176 ± 0.681
3.529AlaPro: 3.529 ± 0.196
1.176AlaGln: 1.176 ± 0.681
2.353AlaArg: 2.353 ± 1.361
2.353AlaSer: 2.353 ± 1.361
1.176AlaThr: 1.176 ± 1.165
3.529AlaVal: 3.529 ± 0.196
1.176AlaTrp: 1.176 ± 1.165
3.529AlaTyr: 3.529 ± 0.196
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.176CysAsp: 1.176 ± 0.681
2.353CysGlu: 2.353 ± 1.361
1.176CysPhe: 1.176 ± 1.165
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.176CysIle: 1.176 ± 0.681
1.176CysLys: 1.176 ± 0.681
1.176CysLeu: 1.176 ± 0.681
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.176CysPro: 1.176 ± 0.681
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.176CysThr: 1.176 ± 0.681
1.176CysVal: 1.176 ± 1.165
0.0CysTrp: 0.0 ± 0.0
1.176CysTyr: 1.176 ± 1.165
0.0CysXaa: 0.0 ± 0.0
Asp
2.353AspAla: 2.353 ± 0.484
0.0AspCys: 0.0 ± 0.0
5.882AspAsp: 5.882 ± 0.288
3.529AspGlu: 3.529 ± 0.196
1.176AspPhe: 1.176 ± 0.681
4.706AspGly: 4.706 ± 2.814
1.176AspHis: 1.176 ± 0.681
2.353AspIle: 2.353 ± 0.484
2.353AspLys: 2.353 ± 0.484
2.353AspLeu: 2.353 ± 0.484
2.353AspMet: 2.353 ± 0.484
1.176AspAsn: 1.176 ± 1.165
2.353AspPro: 2.353 ± 0.484
1.176AspGln: 1.176 ± 0.681
4.706AspArg: 4.706 ± 2.814
4.706AspSer: 4.706 ± 0.877
1.176AspThr: 1.176 ± 1.165
5.882AspVal: 5.882 ± 1.558
2.353AspTrp: 2.353 ± 0.484
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.353GluAla: 2.353 ± 0.484
0.0GluCys: 0.0 ± 0.0
2.353GluAsp: 2.353 ± 1.361
4.706GluGlu: 4.706 ± 0.968
1.176GluPhe: 1.176 ± 1.165
5.882GluGly: 5.882 ± 1.558
0.0GluHis: 0.0 ± 0.0
3.529GluIle: 3.529 ± 0.196
3.529GluLys: 3.529 ± 0.196
7.059GluLeu: 7.059 ± 1.453
1.176GluMet: 1.176 ± 0.681
3.529GluAsn: 3.529 ± 1.649
4.706GluPro: 4.706 ± 0.877
2.353GluGln: 2.353 ± 0.484
5.882GluArg: 5.882 ± 1.558
4.706GluSer: 4.706 ± 2.723
0.0GluThr: 0.0 ± 0.0
7.059GluVal: 7.059 ± 2.239
1.176GluTrp: 1.176 ± 1.165
1.176GluTyr: 1.176 ± 0.681
0.0GluXaa: 0.0 ± 0.0
Phe
4.706PheAla: 4.706 ± 0.877
2.353PheCys: 2.353 ± 1.361
3.529PheAsp: 3.529 ± 0.196
3.529PheGlu: 3.529 ± 2.042
1.176PhePhe: 1.176 ± 1.165
7.059PheGly: 7.059 ± 0.393
0.0PheHis: 0.0 ± 0.0
3.529PheIle: 3.529 ± 1.649
1.176PheLys: 1.176 ± 0.681
4.706PheLeu: 4.706 ± 0.968
1.176PheMet: 1.176 ± 0.681
1.176PheAsn: 1.176 ± 1.165
2.353PhePro: 2.353 ± 0.484
0.0PheGln: 0.0 ± 0.0
3.529PheArg: 3.529 ± 1.649
5.882PheSer: 5.882 ± 2.133
1.176PheThr: 1.176 ± 0.681
10.588PheVal: 10.588 ± 0.589
2.353PheTrp: 2.353 ± 1.361
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.706GlyAla: 4.706 ± 0.877
3.529GlyCys: 3.529 ± 1.649
7.059GlyAsp: 7.059 ± 0.393
2.353GlyGlu: 2.353 ± 0.484
4.706GlyPhe: 4.706 ± 0.968
5.882GlyGly: 5.882 ± 1.558
1.176GlyHis: 1.176 ± 0.681
4.706GlyIle: 4.706 ± 0.968
7.059GlyLys: 7.059 ± 4.084
3.529GlyLeu: 3.529 ± 0.196
1.176GlyMet: 1.176 ± 0.426
0.0GlyAsn: 0.0 ± 0.0
1.176GlyPro: 1.176 ± 0.681
3.529GlyGln: 3.529 ± 1.649
9.412GlyArg: 9.412 ± 1.754
3.529GlySer: 3.529 ± 2.042
2.353GlyThr: 2.353 ± 1.361
5.882GlyVal: 5.882 ± 1.558
2.353GlyTrp: 2.353 ± 2.33
1.176GlyTyr: 1.176 ± 0.681
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.176HisAsp: 1.176 ± 1.165
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.176HisGly: 1.176 ± 0.681
0.0HisHis: 0.0 ± 0.0
1.176HisIle: 1.176 ± 0.681
1.176HisLys: 1.176 ± 1.165
2.353HisLeu: 2.353 ± 2.33
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.176HisArg: 1.176 ± 1.165
0.0HisSer: 0.0 ± 0.0
1.176HisThr: 1.176 ± 0.681
1.176HisVal: 1.176 ± 0.681
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.176IleAla: 1.176 ± 0.681
0.0IleCys: 0.0 ± 0.0
2.353IleAsp: 2.353 ± 0.484
5.882IleGlu: 5.882 ± 0.288
0.0IlePhe: 0.0 ± 0.0
4.706IleGly: 4.706 ± 0.877
0.0IleHis: 0.0 ± 0.0
2.353IleIle: 2.353 ± 0.484
2.353IleLys: 2.353 ± 0.484
11.765IleLeu: 11.765 ± 2.421
1.176IleMet: 1.176 ± 1.165
1.176IleAsn: 1.176 ± 1.165
4.706IlePro: 4.706 ± 2.814
7.059IleGln: 7.059 ± 3.298
0.0IleArg: 0.0 ± 0.0
3.529IleSer: 3.529 ± 1.649
2.353IleThr: 2.353 ± 1.361
7.059IleVal: 7.059 ± 3.298
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.353LysAla: 2.353 ± 1.361
1.176LysCys: 1.176 ± 0.681
1.176LysAsp: 1.176 ± 1.165
1.176LysGlu: 1.176 ± 0.681
5.882LysPhe: 5.882 ± 1.558
2.353LysGly: 2.353 ± 1.361
1.176LysHis: 1.176 ± 1.165
3.529LysIle: 3.529 ± 1.649
5.882LysLys: 5.882 ± 1.558
3.529LysLeu: 3.529 ± 0.196
0.0LysMet: 0.0 ± 0.0
7.059LysAsn: 7.059 ± 2.239
4.706LysPro: 4.706 ± 2.723
4.706LysGln: 4.706 ± 0.877
1.176LysArg: 1.176 ± 1.165
7.059LysSer: 7.059 ± 1.453
0.0LysThr: 0.0 ± 0.0
3.529LysVal: 3.529 ± 1.649
0.0LysTrp: 0.0 ± 0.0
2.353LysTyr: 2.353 ± 1.361
0.0LysXaa: 0.0 ± 0.0
Leu
3.529LeuAla: 3.529 ± 0.196
1.176LeuCys: 1.176 ± 1.165
3.529LeuAsp: 3.529 ± 1.649
4.706LeuGlu: 4.706 ± 2.814
8.235LeuPhe: 8.235 ± 0.772
10.588LeuGly: 10.588 ± 0.589
0.0LeuHis: 0.0 ± 0.0
4.706LeuIle: 4.706 ± 2.814
5.882LeuLys: 5.882 ± 1.558
12.941LeuLeu: 12.941 ± 1.74
2.353LeuMet: 2.353 ± 1.361
2.353LeuAsn: 2.353 ± 2.33
4.706LeuPro: 4.706 ± 0.968
3.529LeuGln: 3.529 ± 1.649
5.882LeuArg: 5.882 ± 0.288
4.706LeuSer: 4.706 ± 2.723
4.706LeuThr: 4.706 ± 0.968
7.059LeuVal: 7.059 ± 0.393
8.235LeuTrp: 8.235 ± 1.074
3.529LeuTyr: 3.529 ± 3.495
0.0LeuXaa: 0.0 ± 0.0
Met
1.176MetAla: 1.176 ± 0.681
0.0MetCys: 0.0 ± 0.0
1.176MetAsp: 1.176 ± 1.165
1.176MetGlu: 1.176 ± 0.681
0.0MetPhe: 0.0 ± 0.0
1.176MetGly: 1.176 ± 0.681
1.176MetHis: 1.176 ± 1.165
0.0MetIle: 0.0 ± 0.0
2.353MetLys: 2.353 ± 0.484
3.529MetLeu: 3.529 ± 0.196
0.0MetMet: 0.0 ± 0.0
1.176MetAsn: 1.176 ± 1.165
1.176MetPro: 1.176 ± 1.165
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.353MetSer: 2.353 ± 1.361
0.0MetThr: 0.0 ± 0.0
3.529MetVal: 3.529 ± 2.042
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.529AsnAla: 3.529 ± 0.196
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
2.353AsnGlu: 2.353 ± 1.361
1.176AsnPhe: 1.176 ± 0.681
1.176AsnGly: 1.176 ± 1.165
0.0AsnHis: 0.0 ± 0.0
3.529AsnIle: 3.529 ± 1.649
0.0AsnLys: 0.0 ± 0.0
4.706AsnLeu: 4.706 ± 0.968
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
3.529AsnPro: 3.529 ± 1.649
0.0AsnGln: 0.0 ± 0.0
3.529AsnArg: 3.529 ± 2.042
1.176AsnSer: 1.176 ± 1.165
0.0AsnThr: 0.0 ± 0.0
5.882AsnVal: 5.882 ± 2.133
0.0AsnTrp: 0.0 ± 0.0
3.529AsnTyr: 3.529 ± 1.649
0.0AsnXaa: 0.0 ± 0.0
Pro
7.059ProAla: 7.059 ± 1.453
0.0ProCys: 0.0 ± 0.0
5.882ProAsp: 5.882 ± 0.288
3.529ProGlu: 3.529 ± 0.196
1.176ProPhe: 1.176 ± 1.165
0.0ProGly: 0.0 ± 0.0
1.176ProHis: 1.176 ± 1.165
1.176ProIle: 1.176 ± 1.165
3.529ProLys: 3.529 ± 0.196
2.353ProLeu: 2.353 ± 0.484
0.0ProMet: 0.0 ± 0.0
1.176ProAsn: 1.176 ± 0.681
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
2.353ProArg: 2.353 ± 0.484
3.529ProSer: 3.529 ± 2.042
4.706ProThr: 4.706 ± 0.968
5.882ProVal: 5.882 ± 1.558
0.0ProTrp: 0.0 ± 0.0
3.529ProTyr: 3.529 ± 2.042
0.0ProXaa: 0.0 ± 0.0
Gln
8.235GlnAla: 8.235 ± 1.074
1.176GlnCys: 1.176 ± 0.681
0.0GlnAsp: 0.0 ± 0.0
5.882GlnGlu: 5.882 ± 0.288
1.176GlnPhe: 1.176 ± 1.165
1.176GlnGly: 1.176 ± 0.681
0.0GlnHis: 0.0 ± 0.0
4.706GlnIle: 4.706 ± 0.877
1.176GlnLys: 1.176 ± 1.165
1.176GlnLeu: 1.176 ± 0.681
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
0.0GlnGln: 0.0 ± 0.0
3.529GlnArg: 3.529 ± 1.649
2.353GlnSer: 2.353 ± 1.361
1.176GlnThr: 1.176 ± 1.165
3.529GlnVal: 3.529 ± 0.196
0.0GlnTrp: 0.0 ± 0.0
1.176GlnTyr: 1.176 ± 1.165
0.0GlnXaa: 0.0 ± 0.0
Arg
1.176ArgAla: 1.176 ± 1.165
1.176ArgCys: 1.176 ± 0.681
2.353ArgAsp: 2.353 ± 1.361
4.706ArgGlu: 4.706 ± 2.723
7.059ArgPhe: 7.059 ± 3.298
3.529ArgGly: 3.529 ± 0.196
1.176ArgHis: 1.176 ± 1.165
3.529ArgIle: 3.529 ± 1.649
4.706ArgLys: 4.706 ± 0.968
5.882ArgLeu: 5.882 ± 2.133
2.353ArgMet: 2.353 ± 0.484
3.529ArgAsn: 3.529 ± 0.196
1.176ArgPro: 1.176 ± 0.681
2.353ArgGln: 2.353 ± 1.361
1.176ArgArg: 1.176 ± 0.681
3.529ArgSer: 3.529 ± 2.042
1.176ArgThr: 1.176 ± 0.681
7.059ArgVal: 7.059 ± 1.453
1.176ArgTrp: 1.176 ± 0.681
1.176ArgTyr: 1.176 ± 0.681
0.0ArgXaa: 0.0 ± 0.0
Ser
5.882SerAla: 5.882 ± 1.558
0.0SerCys: 0.0 ± 0.0
0.0SerAsp: 0.0 ± 0.0
5.882SerGlu: 5.882 ± 1.558
3.529SerPhe: 3.529 ± 0.196
9.412SerGly: 9.412 ± 0.091
0.0SerHis: 0.0 ± 0.0
2.353SerIle: 2.353 ± 1.361
3.529SerLys: 3.529 ± 0.196
3.529SerLeu: 3.529 ± 1.649
2.353SerMet: 2.353 ± 1.361
3.529SerAsn: 3.529 ± 0.196
5.882SerPro: 5.882 ± 3.403
0.0SerGln: 0.0 ± 0.0
3.529SerArg: 3.529 ± 0.196
4.706SerSer: 4.706 ± 2.723
4.706SerThr: 4.706 ± 2.723
3.529SerVal: 3.529 ± 0.196
1.176SerTrp: 1.176 ± 0.681
2.353SerTyr: 2.353 ± 0.484
0.0SerXaa: 0.0 ± 0.0
Thr
1.176ThrAla: 1.176 ± 0.681
0.0ThrCys: 0.0 ± 0.0
1.176ThrAsp: 1.176 ± 0.681
0.0ThrGlu: 0.0 ± 0.0
2.353ThrPhe: 2.353 ± 1.361
3.529ThrGly: 3.529 ± 0.196
0.0ThrHis: 0.0 ± 0.0
3.529ThrIle: 3.529 ± 1.649
0.0ThrLys: 0.0 ± 0.0
2.353ThrLeu: 2.353 ± 0.484
1.176ThrMet: 1.176 ± 0.681
0.0ThrAsn: 0.0 ± 0.0
2.353ThrPro: 2.353 ± 0.484
3.529ThrGln: 3.529 ± 0.196
1.176ThrArg: 1.176 ± 1.165
3.529ThrSer: 3.529 ± 2.042
2.353ThrThr: 2.353 ± 1.361
4.706ThrVal: 4.706 ± 0.877
0.0ThrTrp: 0.0 ± 0.0
1.176ThrTyr: 1.176 ± 0.681
0.0ThrXaa: 0.0 ± 0.0
Val
9.412ValAla: 9.412 ± 0.091
1.176ValCys: 1.176 ± 0.681
5.882ValAsp: 5.882 ± 2.133
2.353ValGlu: 2.353 ± 0.484
11.765ValPhe: 11.765 ± 1.27
8.235ValGly: 8.235 ± 1.074
1.176ValHis: 1.176 ± 0.681
7.059ValIle: 7.059 ± 3.298
4.706ValLys: 4.706 ± 0.877
5.882ValLeu: 5.882 ± 1.558
2.353ValMet: 2.353 ± 0.92
2.353ValAsn: 2.353 ± 1.361
3.529ValPro: 3.529 ± 1.649
4.706ValGln: 4.706 ± 2.723
8.235ValArg: 8.235 ± 1.074
8.235ValSer: 8.235 ± 0.772
2.353ValThr: 2.353 ± 1.361
4.706ValVal: 4.706 ± 0.968
2.353ValTrp: 2.353 ± 1.361
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.176TrpAsp: 1.176 ± 1.165
0.0TrpGlu: 0.0 ± 0.0
1.176TrpPhe: 1.176 ± 0.681
1.176TrpGly: 1.176 ± 0.681
0.0TrpHis: 0.0 ± 0.0
1.176TrpIle: 1.176 ± 0.681
0.0TrpLys: 0.0 ± 0.0
7.059TrpLeu: 7.059 ± 3.298
0.0TrpMet: 0.0 ± 0.0
2.353TrpAsn: 2.353 ± 0.484
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.353TrpArg: 2.353 ± 1.361
0.0TrpSer: 0.0 ± 0.0
1.176TrpThr: 1.176 ± 1.165
3.529TrpVal: 3.529 ± 2.042
1.176TrpTrp: 1.176 ± 0.681
1.176TrpTyr: 1.176 ± 0.681
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.176TyrAla: 1.176 ± 1.165
0.0TyrCys: 0.0 ± 0.0
2.353TyrAsp: 2.353 ± 1.361
3.529TyrGlu: 3.529 ± 2.042
1.176TyrPhe: 1.176 ± 0.681
1.176TyrGly: 1.176 ± 1.165
2.353TyrHis: 2.353 ± 0.484
1.176TyrIle: 1.176 ± 1.165
1.176TyrLys: 1.176 ± 1.165
5.882TyrLeu: 5.882 ± 1.558
0.0TyrMet: 0.0 ± 0.0
2.353TyrAsn: 2.353 ± 2.33
0.0TyrPro: 0.0 ± 0.0
2.353TyrGln: 2.353 ± 0.484
0.0TyrArg: 0.0 ± 0.0
0.0TyrSer: 0.0 ± 0.0
1.176TyrThr: 1.176 ± 0.681
1.176TyrVal: 1.176 ± 0.681
0.0TyrTrp: 0.0 ± 0.0
1.176TyrTyr: 1.176 ± 1.165
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (851 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski