Circovirus sp.

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cressdnaviricota; Arfiviricetes; Cirlivirales; Circoviridae; Circovirus; unclassified Circovirus

Average proteome isoelectric point is 8.33

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A2K9YNB2|A0A2K9YNB2_9CIRC Capsid protein OS=Circovirus sp. OX=1964372 GN=Cap PE=4 SV=1
MM1 pKa = 7.86SGRR4 pKa = 11.84TRR6 pKa = 11.84NWCFTSYY13 pKa = 10.9EE14 pKa = 3.98EE15 pKa = 4.77TMTEE19 pKa = 4.37FKK21 pKa = 10.85SEE23 pKa = 3.76AMVYY27 pKa = 9.76LIVGAEE33 pKa = 3.87ICPTTNKK40 pKa = 10.05SHH42 pKa = 5.61WQGFVVFKK50 pKa = 10.52EE51 pKa = 4.31SKK53 pKa = 9.0TMSAAKK59 pKa = 9.96IFLGKK64 pKa = 8.91TSHH67 pKa = 7.82LEE69 pKa = 3.98MMKK72 pKa = 9.51GTHH75 pKa = 5.78KK76 pKa = 10.51QAADD80 pKa = 3.39YY81 pKa = 10.27CKK83 pKa = 10.11KK84 pKa = 10.2EE85 pKa = 3.76KK86 pKa = 10.3RR87 pKa = 11.84FKK89 pKa = 11.06EE90 pKa = 4.05FGTFPRR96 pKa = 11.84QGKK99 pKa = 10.14RR100 pKa = 11.84NDD102 pKa = 3.57LEE104 pKa = 4.75EE105 pKa = 4.14VVQMVNDD112 pKa = 4.05GTDD115 pKa = 2.72ILAIAEE121 pKa = 4.14QCPMQMIKK129 pKa = 10.37YY130 pKa = 9.29GKK132 pKa = 10.23GILALKK138 pKa = 10.74AMADD142 pKa = 3.43QRR144 pKa = 11.84LAPEE148 pKa = 3.84WRR150 pKa = 11.84DD151 pKa = 3.46VNVTVLWGPSGTGKK165 pKa = 8.23TRR167 pKa = 11.84TAVEE171 pKa = 4.33SSPDD175 pKa = 3.7YY176 pKa = 10.57YY177 pKa = 10.55IKK179 pKa = 10.84DD180 pKa = 3.82PSNKK184 pKa = 8.99WFDD187 pKa = 3.7GYY189 pKa = 11.22VGQKK193 pKa = 8.38TLILDD198 pKa = 3.62EE199 pKa = 5.5FMPEE203 pKa = 3.98CCPWATLLRR212 pKa = 11.84WLDD215 pKa = 3.75GYY217 pKa = 11.02KK218 pKa = 10.5LQVEE222 pKa = 4.82TKK224 pKa = 10.14GGTTFAMWTTVYY236 pKa = 8.73ITSNIPPDD244 pKa = 3.02KK245 pKa = 10.02WYY247 pKa = 10.9KK248 pKa = 10.9NDD250 pKa = 3.38FAPLKK255 pKa = 10.56RR256 pKa = 11.84RR257 pKa = 11.84ITQIEE262 pKa = 4.25HH263 pKa = 6.64LGSLPRR269 pKa = 11.84SLEE272 pKa = 3.68PHH274 pKa = 6.41KK275 pKa = 10.89PPVQKK280 pKa = 10.56HH281 pKa = 4.51SPEE284 pKa = 4.23VPGNTIPALQTVSTPGFDD302 pKa = 3.5SFAA305 pKa = 5.17

Molecular weight: 34.66 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A2K9YNB2|A0A2K9YNB2_9CIRC Capsid protein OS=Circovirus sp. OX=1964372 GN=Cap PE=4 SV=1
MM1 pKa = 7.19PFKK4 pKa = 10.48RR5 pKa = 11.84KK6 pKa = 8.83SHH8 pKa = 5.25TRR10 pKa = 11.84STAAKK15 pKa = 7.8TRR17 pKa = 11.84RR18 pKa = 11.84RR19 pKa = 11.84YY20 pKa = 9.27KK21 pKa = 10.58RR22 pKa = 11.84KK23 pKa = 7.95FTKK26 pKa = 9.86SRR28 pKa = 11.84KK29 pKa = 4.28TTRR32 pKa = 11.84PHH34 pKa = 5.0ATSMRR39 pKa = 11.84GPLKK43 pKa = 10.56LYY45 pKa = 10.77GGFAPFPPTYY55 pKa = 8.88SAKK58 pKa = 8.75MHH60 pKa = 5.47YY61 pKa = 10.26VEE63 pKa = 4.97NFSLATGTAGVMGTSAKK80 pKa = 10.34VSLNSLYY87 pKa = 10.62DD88 pKa = 3.7PNMSGSGHH96 pKa = 5.37QPYY99 pKa = 10.29GYY101 pKa = 10.47DD102 pKa = 3.88QITALYY108 pKa = 9.36RR109 pKa = 11.84RR110 pKa = 11.84YY111 pKa = 9.53IVSGVKK117 pKa = 10.07INITFTNPNDD127 pKa = 4.01DD128 pKa = 4.05GLVVAVMIQASGGVGAIAGQTADD151 pKa = 4.12IIKK154 pKa = 8.66EE155 pKa = 4.01QPLSWTHH162 pKa = 6.98PINNTGSQVCHH173 pKa = 5.96FRR175 pKa = 11.84QYY177 pKa = 11.59LPLQKK182 pKa = 10.38VEE184 pKa = 4.69GLMKK188 pKa = 10.05VQWIANQDD196 pKa = 3.34QYY198 pKa = 11.81GALYY202 pKa = 8.27TASPSLQPFLLMSVGSDD219 pKa = 3.05AGSGAAAIMARR230 pKa = 11.84IEE232 pKa = 3.79LTYY235 pKa = 8.83YY236 pKa = 9.14TRR238 pKa = 11.84FYY240 pKa = 11.6DD241 pKa = 5.52RR242 pKa = 11.84ILQAYY247 pKa = 8.08SS248 pKa = 2.92

Molecular weight: 27.43 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2

0

2

553

248

305

276.5

31.04

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.414 ± 1.12

1.266 ± 0.52

3.978 ± 0.453

4.34 ± 1.643

4.159 ± 0.319

7.595 ± 0.526

2.17 ± 0.15

4.882 ± 0.217

7.414 ± 1.066

6.691 ± 0.099

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

3.797 ± 0.101

3.255 ± 0.225

6.148 ± 0.303

4.521 ± 0.434

4.882 ± 0.702

6.872 ± 0.961

8.499 ± 0.262

5.425 ± 0.11

1.989 ± 0.712

4.702 ± 1.054
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski