Amino acid dipepetide frequency for Circovirus sp.

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.058AlaAla: 9.058 ± 2.045
0.0AlaCys: 0.0 ± 0.0
5.435AlaAsp: 5.435 ± 0.931
3.623AlaGlu: 3.623 ± 2.419
0.0AlaPhe: 0.0 ± 0.0
5.435AlaGly: 5.435 ± 4.465
0.0AlaHis: 0.0 ± 0.0
5.435AlaIle: 5.435 ± 1.767
7.246AlaLys: 7.246 ± 3.255
7.246AlaLeu: 7.246 ± 0.557
7.246AlaMet: 7.246 ± 4.283
1.812AlaAsn: 1.812 ± 1.488
5.435AlaPro: 5.435 ± 0.931
0.0AlaGln: 0.0 ± 0.0
1.812AlaArg: 1.812 ± 1.488
3.623AlaSer: 3.623 ± 2.976
5.435AlaThr: 5.435 ± 1.767
3.623AlaVal: 3.623 ± 0.279
0.0AlaTrp: 0.0 ± 0.0
1.812AlaTyr: 1.812 ± 1.488
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.812CysCys: 1.812 ± 1.21
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.812CysPhe: 1.812 ± 1.21
0.0CysGly: 0.0 ± 0.0
1.812CysHis: 1.812 ± 1.488
0.0CysIle: 0.0 ± 0.0
1.812CysLys: 1.812 ± 1.21
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
5.435CysPro: 5.435 ± 3.629
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.812AspAla: 1.812 ± 1.488
0.0AspCys: 0.0 ± 0.0
1.812AspAsp: 1.812 ± 1.488
1.812AspGlu: 1.812 ± 1.21
1.812AspPhe: 1.812 ± 1.21
7.246AspGly: 7.246 ± 2.141
0.0AspHis: 0.0 ± 0.0
3.623AspIle: 3.623 ± 0.279
1.812AspLys: 1.812 ± 1.21
1.812AspLeu: 1.812 ± 1.21
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
3.623AspPro: 3.623 ± 0.279
5.435AspGln: 5.435 ± 1.767
1.812AspArg: 1.812 ± 1.488
1.812AspSer: 1.812 ± 1.21
0.0AspThr: 0.0 ± 0.0
1.812AspVal: 1.812 ± 1.21
0.0AspTrp: 0.0 ± 0.0
3.623AspTyr: 3.623 ± 2.419
0.0AspXaa: 0.0 ± 0.0
Glu
1.812GluAla: 1.812 ± 1.21
1.812GluCys: 1.812 ± 1.21
0.0GluAsp: 0.0 ± 0.0
3.623GluGlu: 3.623 ± 2.419
5.435GluPhe: 5.435 ± 3.629
1.812GluGly: 1.812 ± 1.488
1.812GluHis: 1.812 ± 1.21
1.812GluIle: 1.812 ± 1.21
1.812GluLys: 1.812 ± 1.21
1.812GluLeu: 1.812 ± 1.488
1.812GluMet: 1.812 ± 1.21
1.812GluAsn: 1.812 ± 1.488
1.812GluPro: 1.812 ± 1.21
3.623GluGln: 3.623 ± 0.279
0.0GluArg: 0.0 ± 0.0
3.623GluSer: 3.623 ± 2.419
3.623GluThr: 3.623 ± 2.419
3.623GluVal: 3.623 ± 2.419
1.812GluTrp: 1.812 ± 1.21
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
7.246PheAla: 7.246 ± 2.141
0.0PheCys: 0.0 ± 0.0
3.623PheAsp: 3.623 ± 2.419
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
1.812PheGly: 1.812 ± 1.21
0.0PheHis: 0.0 ± 0.0
0.0PheIle: 0.0 ± 0.0
7.246PheLys: 7.246 ± 2.141
3.623PheLeu: 3.623 ± 0.279
1.812PheMet: 1.812 ± 1.21
0.0PheAsn: 0.0 ± 0.0
3.623PhePro: 3.623 ± 0.279
0.0PheGln: 0.0 ± 0.0
1.812PheArg: 1.812 ± 1.488
1.812PheSer: 1.812 ± 1.488
5.435PheThr: 5.435 ± 1.767
1.812PheVal: 1.812 ± 1.21
0.0PheTrp: 0.0 ± 0.0
1.812PheTyr: 1.812 ± 1.488
0.0PheXaa: 0.0 ± 0.0
Gly
7.246GlyAla: 7.246 ± 3.255
0.0GlyCys: 0.0 ± 0.0
0.0GlyAsp: 0.0 ± 0.0
0.0GlyGlu: 0.0 ± 0.0
5.435GlyPhe: 5.435 ± 0.931
5.435GlyGly: 5.435 ± 1.767
1.812GlyHis: 1.812 ± 1.488
1.812GlyIle: 1.812 ± 1.21
7.246GlyLys: 7.246 ± 4.838
3.623GlyLeu: 3.623 ± 2.976
0.0GlyMet: 0.0 ± 0.0
1.812GlyAsn: 1.812 ± 1.21
3.623GlyPro: 3.623 ± 0.279
3.623GlyGln: 3.623 ± 0.279
1.812GlyArg: 1.812 ± 1.21
9.058GlySer: 9.058 ± 4.743
12.681GlyThr: 12.681 ± 3.072
5.435GlyVal: 5.435 ± 4.465
0.0GlyTrp: 0.0 ± 0.0
5.435GlyTyr: 5.435 ± 0.931
0.0GlyXaa: 0.0 ± 0.0
His
1.812HisAla: 1.812 ± 1.488
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.812HisPhe: 1.812 ± 1.488
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
3.623HisLys: 3.623 ± 2.419
3.623HisLeu: 3.623 ± 2.419
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.812HisPro: 1.812 ± 1.488
1.812HisGln: 1.812 ± 1.488
0.0HisArg: 0.0 ± 0.0
1.812HisSer: 1.812 ± 1.21
1.812HisThr: 1.812 ± 1.488
0.0HisVal: 0.0 ± 0.0
1.812HisTrp: 1.812 ± 1.21
1.812HisTyr: 1.812 ± 1.488
0.0HisXaa: 0.0 ± 0.0
Ile
5.435IleAla: 5.435 ± 1.767
1.812IleCys: 1.812 ± 1.21
0.0IleAsp: 0.0 ± 0.0
3.623IleGlu: 3.623 ± 0.279
1.812IlePhe: 1.812 ± 1.21
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
1.812IleIle: 1.812 ± 1.488
5.435IleLys: 5.435 ± 0.931
7.246IleLeu: 7.246 ± 2.141
1.812IleMet: 1.812 ± 1.488
3.623IleAsn: 3.623 ± 2.976
3.623IlePro: 3.623 ± 2.419
1.812IleGln: 1.812 ± 1.488
0.0IleArg: 0.0 ± 0.0
0.0IleSer: 0.0 ± 0.0
7.246IleThr: 7.246 ± 0.557
3.623IleVal: 3.623 ± 0.279
0.0IleTrp: 0.0 ± 0.0
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.812LysAla: 1.812 ± 1.21
0.0LysCys: 0.0 ± 0.0
1.812LysAsp: 1.812 ± 1.21
7.246LysGlu: 7.246 ± 2.141
1.812LysPhe: 1.812 ± 1.488
5.435LysGly: 5.435 ± 3.629
1.812LysHis: 1.812 ± 1.21
3.623LysIle: 3.623 ± 0.279
1.812LysLys: 1.812 ± 1.21
3.623LysLeu: 3.623 ± 0.279
1.812LysMet: 1.812 ± 1.488
1.812LysAsn: 1.812 ± 1.21
1.812LysPro: 1.812 ± 1.21
1.812LysGln: 1.812 ± 1.21
9.058LysArg: 9.058 ± 0.652
7.246LysSer: 7.246 ± 0.557
10.87LysThr: 10.87 ± 1.862
5.435LysVal: 5.435 ± 4.465
3.623LysTrp: 3.623 ± 2.419
1.812LysTyr: 1.812 ± 1.21
0.0LysXaa: 0.0 ± 0.0
Leu
7.246LeuAla: 7.246 ± 2.141
0.0LeuCys: 0.0 ± 0.0
3.623LeuAsp: 3.623 ± 2.419
5.435LeuGlu: 5.435 ± 3.629
0.0LeuPhe: 0.0 ± 0.0
3.623LeuGly: 3.623 ± 2.419
0.0LeuHis: 0.0 ± 0.0
3.623LeuIle: 3.623 ± 2.419
5.435LeuLys: 5.435 ± 0.931
3.623LeuLeu: 3.623 ± 0.279
3.623LeuMet: 3.623 ± 2.976
1.812LeuAsn: 1.812 ± 1.488
3.623LeuPro: 3.623 ± 0.279
9.058LeuGln: 9.058 ± 2.045
1.812LeuArg: 1.812 ± 1.21
1.812LeuSer: 1.812 ± 1.488
1.812LeuThr: 1.812 ± 1.488
1.812LeuVal: 1.812 ± 1.488
1.812LeuTrp: 1.812 ± 1.21
7.246LeuTyr: 7.246 ± 5.953
0.0LeuXaa: 0.0 ± 0.0
Met
3.623MetAla: 3.623 ± 0.279
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
0.0MetPhe: 0.0 ± 0.0
1.812MetGly: 1.812 ± 1.488
1.812MetHis: 1.812 ± 1.488
3.623MetIle: 3.623 ± 0.279
3.623MetLys: 3.623 ± 0.279
0.0MetLeu: 0.0 ± 0.0
1.812MetMet: 1.812 ± 1.21
0.0MetAsn: 0.0 ± 0.0
3.623MetPro: 3.623 ± 0.279
1.812MetGln: 1.812 ± 1.21
1.812MetArg: 1.812 ± 1.488
7.246MetSer: 7.246 ± 0.557
1.812MetThr: 1.812 ± 1.21
3.623MetVal: 3.623 ± 2.419
1.812MetTrp: 1.812 ± 1.21
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
7.246AsnAsp: 7.246 ± 2.141
0.0AsnGlu: 0.0 ± 0.0
1.812AsnPhe: 1.812 ± 1.488
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
3.623AsnIle: 3.623 ± 0.279
3.623AsnLys: 3.623 ± 2.419
0.0AsnLeu: 0.0 ± 0.0
1.812AsnMet: 1.812 ± 1.488
1.812AsnAsn: 1.812 ± 1.488
1.812AsnPro: 1.812 ± 1.488
1.812AsnGln: 1.812 ± 1.488
0.0AsnArg: 0.0 ± 0.0
1.812AsnSer: 1.812 ± 1.488
3.623AsnThr: 3.623 ± 0.279
1.812AsnVal: 1.812 ± 1.21
1.812AsnTrp: 1.812 ± 1.21
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.812ProAla: 1.812 ± 1.21
0.0ProCys: 0.0 ± 0.0
3.623ProAsp: 3.623 ± 2.419
5.435ProGlu: 5.435 ± 3.629
5.435ProPhe: 5.435 ± 4.465
3.623ProGly: 3.623 ± 2.419
3.623ProHis: 3.623 ± 0.279
1.812ProIle: 1.812 ± 1.488
0.0ProLys: 0.0 ± 0.0
7.246ProLeu: 7.246 ± 3.255
1.812ProMet: 1.812 ± 1.21
3.623ProAsn: 3.623 ± 2.976
5.435ProPro: 5.435 ± 0.931
0.0ProGln: 0.0 ± 0.0
3.623ProArg: 3.623 ± 2.419
5.435ProSer: 5.435 ± 0.931
3.623ProThr: 3.623 ± 0.279
1.812ProVal: 1.812 ± 1.21
1.812ProTrp: 1.812 ± 1.21
1.812ProTyr: 1.812 ± 1.488
0.0ProXaa: 0.0 ± 0.0
Gln
5.435GlnAla: 5.435 ± 1.767
1.812GlnCys: 1.812 ± 1.21
1.812GlnAsp: 1.812 ± 1.488
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
3.623GlnGly: 3.623 ± 2.419
0.0GlnHis: 0.0 ± 0.0
3.623GlnIle: 3.623 ± 0.279
5.435GlnLys: 5.435 ± 0.931
0.0GlnLeu: 0.0 ± 0.0
3.623GlnMet: 3.623 ± 2.419
0.0GlnAsn: 0.0 ± 0.0
5.435GlnPro: 5.435 ± 4.465
0.0GlnGln: 0.0 ± 0.0
1.812GlnArg: 1.812 ± 1.21
0.0GlnSer: 0.0 ± 0.0
3.623GlnThr: 3.623 ± 0.279
3.623GlnVal: 3.623 ± 0.279
1.812GlnTrp: 1.812 ± 1.488
3.623GlnTyr: 3.623 ± 2.976
0.0GlnXaa: 0.0 ± 0.0
Arg
0.0ArgAla: 0.0 ± 0.0
0.0ArgCys: 0.0 ± 0.0
1.812ArgAsp: 1.812 ± 1.21
0.0ArgGlu: 0.0 ± 0.0
3.623ArgPhe: 3.623 ± 0.279
1.812ArgGly: 1.812 ± 1.488
0.0ArgHis: 0.0 ± 0.0
5.435ArgIle: 5.435 ± 1.767
5.435ArgLys: 5.435 ± 4.465
1.812ArgLeu: 1.812 ± 1.21
0.0ArgMet: 0.0 ± 0.0
3.623ArgAsn: 3.623 ± 2.419
1.812ArgPro: 1.812 ± 1.488
3.623ArgGln: 3.623 ± 0.279
7.246ArgArg: 7.246 ± 3.255
3.623ArgSer: 3.623 ± 0.279
3.623ArgThr: 3.623 ± 2.419
0.0ArgVal: 0.0 ± 0.0
1.812ArgTrp: 1.812 ± 1.21
3.623ArgTyr: 3.623 ± 2.976
0.0ArgXaa: 0.0 ± 0.0
Ser
5.435SerAla: 5.435 ± 1.767
0.0SerCys: 0.0 ± 0.0
1.812SerAsp: 1.812 ± 1.488
1.812SerGlu: 1.812 ± 1.21
1.812SerPhe: 1.812 ± 1.21
12.681SerGly: 12.681 ± 5.022
5.435SerHis: 5.435 ± 0.931
0.0SerIle: 0.0 ± 0.0
1.812SerLys: 1.812 ± 1.21
10.87SerLeu: 10.87 ± 3.534
1.812SerMet: 1.812 ± 2.319
3.623SerAsn: 3.623 ± 2.419
5.435SerPro: 5.435 ± 0.931
1.812SerGln: 1.812 ± 1.488
1.812SerArg: 1.812 ± 1.488
1.812SerSer: 1.812 ± 1.21
3.623SerThr: 3.623 ± 0.279
1.812SerVal: 1.812 ± 1.488
1.812SerTrp: 1.812 ± 1.488
1.812SerTyr: 1.812 ± 1.21
0.0SerXaa: 0.0 ± 0.0
Thr
10.87ThrAla: 10.87 ± 6.231
0.0ThrCys: 0.0 ± 0.0
1.812ThrAsp: 1.812 ± 1.21
1.812ThrGlu: 1.812 ± 1.21
5.435ThrPhe: 5.435 ± 0.931
5.435ThrGly: 5.435 ± 1.767
3.623ThrHis: 3.623 ± 0.279
1.812ThrIle: 1.812 ± 1.21
3.623ThrLys: 3.623 ± 0.279
3.623ThrLeu: 3.623 ± 2.419
3.623ThrMet: 3.623 ± 2.419
3.623ThrAsn: 3.623 ± 0.279
1.812ThrPro: 1.812 ± 1.21
1.812ThrGln: 1.812 ± 1.21
10.87ThrArg: 10.87 ± 3.534
9.058ThrSer: 9.058 ± 0.652
7.246ThrThr: 7.246 ± 2.141
5.435ThrVal: 5.435 ± 3.629
0.0ThrTrp: 0.0 ± 0.0
3.623ThrTyr: 3.623 ± 2.976
0.0ThrXaa: 0.0 ± 0.0
Val
1.812ValAla: 1.812 ± 1.488
1.812ValCys: 1.812 ± 1.488
0.0ValAsp: 0.0 ± 0.0
7.246ValGlu: 7.246 ± 0.557
1.812ValPhe: 1.812 ± 1.21
7.246ValGly: 7.246 ± 0.557
0.0ValHis: 0.0 ± 0.0
0.0ValIle: 0.0 ± 0.0
1.812ValLys: 1.812 ± 1.488
1.812ValLeu: 1.812 ± 1.21
3.623ValMet: 3.623 ± 2.976
3.623ValAsn: 3.623 ± 2.419
1.812ValPro: 1.812 ± 1.21
5.435ValGln: 5.435 ± 0.931
0.0ValArg: 0.0 ± 0.0
5.435ValSer: 5.435 ± 1.767
1.812ValThr: 1.812 ± 1.21
5.435ValVal: 5.435 ± 0.931
0.0ValTrp: 0.0 ± 0.0
3.623ValTyr: 3.623 ± 2.419
0.0ValXaa: 0.0 ± 0.0
Trp
1.812TrpAla: 1.812 ± 1.21
1.812TrpCys: 1.812 ± 1.21
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.812TrpPhe: 1.812 ± 1.21
1.812TrpGly: 1.812 ± 1.21
0.0TrpHis: 0.0 ± 0.0
1.812TrpIle: 1.812 ± 1.488
0.0TrpLys: 0.0 ± 0.0
1.812TrpLeu: 1.812 ± 1.21
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.812TrpGln: 1.812 ± 1.21
1.812TrpArg: 1.812 ± 1.21
0.0TrpSer: 0.0 ± 0.0
3.623TrpThr: 3.623 ± 0.279
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.812TrpTyr: 1.812 ± 1.21
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
1.812TyrCys: 1.812 ± 1.21
5.435TyrAsp: 5.435 ± 4.465
1.812TyrGlu: 1.812 ± 1.21
0.0TyrPhe: 0.0 ± 0.0
7.246TyrGly: 7.246 ± 3.255
0.0TyrHis: 0.0 ± 0.0
5.435TyrIle: 5.435 ± 0.931
5.435TyrLys: 5.435 ± 0.931
3.623TyrLeu: 3.623 ± 0.279
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
1.812TyrArg: 1.812 ± 1.488
3.623TyrSer: 3.623 ± 2.976
3.623TyrThr: 3.623 ± 2.976
3.623TyrVal: 3.623 ± 0.279
0.0TyrTrp: 0.0 ± 0.0
3.623TyrTyr: 3.623 ± 0.279
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (553 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski