Amino acid dipepetide frequency for Apple luteovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.616AlaAla: 6.616 ± 1.084
0.992AlaCys: 0.992 ± 0.404
3.97AlaAsp: 3.97 ± 1.252
6.285AlaGlu: 6.285 ± 1.199
3.639AlaPhe: 3.639 ± 0.803
4.3AlaGly: 4.3 ± 1.048
0.331AlaHis: 0.331 ± 0.374
1.654AlaIle: 1.654 ± 0.849
2.977AlaLys: 2.977 ± 0.745
5.293AlaLeu: 5.293 ± 0.894
1.323AlaMet: 1.323 ± 0.337
2.646AlaAsn: 2.646 ± 0.712
5.954AlaPro: 5.954 ± 1.133
1.985AlaGln: 1.985 ± 0.709
5.954AlaArg: 5.954 ± 1.675
5.293AlaSer: 5.293 ± 0.845
2.316AlaThr: 2.316 ± 0.85
2.977AlaVal: 2.977 ± 1.074
0.0AlaTrp: 0.0 ± 0.0
2.646AlaTyr: 2.646 ± 0.576
0.0AlaXaa: 0.0 ± 0.0
Cys
1.323CysAla: 1.323 ± 0.343
0.0CysCys: 0.0 ± 0.0
0.331CysAsp: 0.331 ± 0.368
0.992CysGlu: 0.992 ± 0.425
0.331CysPhe: 0.331 ± 0.473
1.654CysGly: 1.654 ± 0.473
0.992CysHis: 0.992 ± 0.261
0.662CysIle: 0.662 ± 0.369
0.992CysLys: 0.992 ± 0.425
0.331CysLeu: 0.331 ± 0.23
0.0CysMet: 0.0 ± 0.0
0.331CysAsn: 0.331 ± 0.23
0.662CysPro: 0.662 ± 0.369
0.662CysGln: 0.662 ± 0.369
1.654CysArg: 1.654 ± 0.765
0.992CysSer: 0.992 ± 0.334
1.654CysThr: 1.654 ± 0.561
1.654CysVal: 1.654 ± 0.804
0.331CysTrp: 0.331 ± 0.249
1.654CysTyr: 1.654 ± 0.678
0.0CysXaa: 0.0 ± 0.0
Asp
6.285AspAla: 6.285 ± 1.902
0.992AspCys: 0.992 ± 0.457
4.3AspAsp: 4.3 ± 0.827
5.293AspGlu: 5.293 ± 0.875
3.308AspPhe: 3.308 ± 0.877
2.316AspGly: 2.316 ± 0.802
0.0AspHis: 0.0 ± 0.0
1.985AspIle: 1.985 ± 0.547
1.985AspLys: 1.985 ± 0.547
4.962AspLeu: 4.962 ± 0.724
1.323AspMet: 1.323 ± 0.63
0.992AspAsn: 0.992 ± 0.425
2.646AspPro: 2.646 ± 0.867
1.985AspGln: 1.985 ± 0.626
0.662AspArg: 0.662 ± 0.374
2.316AspSer: 2.316 ± 0.914
2.646AspThr: 2.646 ± 0.9
4.631AspVal: 4.631 ± 1.012
0.662AspTrp: 0.662 ± 0.262
1.985AspTyr: 1.985 ± 0.93
0.0AspXaa: 0.0 ± 0.0
Glu
2.977GluAla: 2.977 ± 0.741
0.992GluCys: 0.992 ± 0.404
3.639GluAsp: 3.639 ± 0.797
4.631GluGlu: 4.631 ± 1.809
1.985GluPhe: 1.985 ± 0.626
4.3GluGly: 4.3 ± 1.009
0.331GluHis: 0.331 ± 0.23
4.3GluIle: 4.3 ± 0.85
2.646GluLys: 2.646 ± 1.023
7.939GluLeu: 7.939 ± 2.066
1.985GluMet: 1.985 ± 1.039
1.654GluAsn: 1.654 ± 0.517
5.624GluPro: 5.624 ± 1.341
2.316GluGln: 2.316 ± 0.536
5.624GluArg: 5.624 ± 1.111
3.308GluSer: 3.308 ± 0.545
1.323GluThr: 1.323 ± 0.402
3.639GluVal: 3.639 ± 0.773
0.992GluTrp: 0.992 ± 0.261
0.992GluTyr: 0.992 ± 0.505
0.0GluXaa: 0.0 ± 0.0
Phe
2.316PheAla: 2.316 ± 0.75
0.331PheCys: 0.331 ± 0.23
2.646PheAsp: 2.646 ± 0.82
2.316PheGlu: 2.316 ± 0.785
2.646PhePhe: 2.646 ± 0.826
2.646PheGly: 2.646 ± 0.625
1.654PheHis: 1.654 ± 0.394
1.654PheIle: 1.654 ± 0.39
4.3PheLys: 4.3 ± 1.425
3.639PheLeu: 3.639 ± 0.771
0.992PheMet: 0.992 ± 0.46
0.992PheAsn: 0.992 ± 0.457
1.323PhePro: 1.323 ± 0.778
1.985PheGln: 1.985 ± 0.548
1.985PheArg: 1.985 ± 0.718
1.985PheSer: 1.985 ± 0.506
2.316PheThr: 2.316 ± 0.602
2.316PheVal: 2.316 ± 0.802
0.662PheTrp: 0.662 ± 0.262
0.662PheTyr: 0.662 ± 0.315
0.0PheXaa: 0.0 ± 0.0
Gly
2.646GlyAla: 2.646 ± 0.42
1.654GlyCys: 1.654 ± 0.541
2.977GlyAsp: 2.977 ± 0.944
2.977GlyGlu: 2.977 ± 1.237
1.654GlyPhe: 1.654 ± 0.77
3.97GlyGly: 3.97 ± 2.131
0.662GlyHis: 0.662 ± 0.262
1.654GlyIle: 1.654 ± 0.837
4.3GlyLys: 4.3 ± 0.894
3.639GlyLeu: 3.639 ± 0.823
0.992GlyMet: 0.992 ± 0.618
2.316GlyAsn: 2.316 ± 0.896
2.646GlyPro: 2.646 ± 1.097
3.97GlyGln: 3.97 ± 0.835
4.962GlyArg: 4.962 ± 0.961
4.962GlySer: 4.962 ± 1.443
1.323GlyThr: 1.323 ± 1.056
4.962GlyVal: 4.962 ± 0.917
1.654GlyTrp: 1.654 ± 0.662
3.639GlyTyr: 3.639 ± 0.645
0.0GlyXaa: 0.0 ± 0.0
His
0.331HisAla: 0.331 ± 0.23
0.0HisCys: 0.0 ± 0.0
0.992HisAsp: 0.992 ± 0.261
0.662HisGlu: 0.662 ± 0.315
0.331HisPhe: 0.331 ± 0.249
0.662HisGly: 0.662 ± 0.435
0.0HisHis: 0.0 ± 0.0
0.992HisIle: 0.992 ± 0.261
0.992HisLys: 0.992 ± 0.261
1.985HisLeu: 1.985 ± 1.088
0.0HisMet: 0.0 ± 0.0
0.662HisAsn: 0.662 ± 0.46
0.331HisPro: 0.331 ± 0.249
0.662HisGln: 0.662 ± 0.389
0.992HisArg: 0.992 ± 0.527
2.977HisSer: 2.977 ± 1.381
1.323HisThr: 1.323 ± 0.705
1.323HisVal: 1.323 ± 0.362
0.331HisTrp: 0.331 ± 0.23
0.662HisTyr: 0.662 ± 0.315
0.0HisXaa: 0.0 ± 0.0
Ile
2.977IleAla: 2.977 ± 0.789
1.323IleCys: 1.323 ± 0.651
2.316IleAsp: 2.316 ± 0.831
2.977IleGlu: 2.977 ± 0.745
0.331IlePhe: 0.331 ± 0.23
2.977IleGly: 2.977 ± 0.45
0.992IleHis: 0.992 ± 0.261
2.316IleIle: 2.316 ± 0.969
3.97IleLys: 3.97 ± 0.65
2.977IleLeu: 2.977 ± 0.848
1.323IleMet: 1.323 ± 0.46
2.646IleAsn: 2.646 ± 0.371
1.654IlePro: 1.654 ± 0.417
0.0IleGln: 0.0 ± 0.0
3.97IleArg: 3.97 ± 0.912
3.639IleSer: 3.639 ± 0.589
2.646IleThr: 2.646 ± 1.319
3.97IleVal: 3.97 ± 0.982
0.331IleTrp: 0.331 ± 0.249
1.654IleTyr: 1.654 ± 0.75
0.0IleXaa: 0.0 ± 0.0
Lys
4.631LysAla: 4.631 ± 0.907
0.662LysCys: 0.662 ± 0.369
3.308LysAsp: 3.308 ± 0.973
0.992LysGlu: 0.992 ± 0.456
4.3LysPhe: 4.3 ± 0.979
1.985LysGly: 1.985 ± 0.547
0.331LysHis: 0.331 ± 0.23
3.308LysIle: 3.308 ± 0.677
2.646LysLys: 2.646 ± 0.586
4.631LysLeu: 4.631 ± 1.046
1.654LysMet: 1.654 ± 0.456
2.316LysAsn: 2.316 ± 0.794
5.624LysPro: 5.624 ± 1.367
1.654LysGln: 1.654 ± 0.421
4.3LysArg: 4.3 ± 1.22
3.308LysSer: 3.308 ± 0.825
3.97LysThr: 3.97 ± 1.2
5.954LysVal: 5.954 ± 1.605
1.985LysTrp: 1.985 ± 0.577
2.646LysTyr: 2.646 ± 0.552
0.331LysXaa: 0.331 ± 0.249
Leu
6.285LeuAla: 6.285 ± 2.263
2.977LeuCys: 2.977 ± 0.809
2.977LeuAsp: 2.977 ± 1.023
5.624LeuGlu: 5.624 ± 1.368
2.316LeuPhe: 2.316 ± 0.603
3.639LeuGly: 3.639 ± 1.108
1.985LeuHis: 1.985 ± 0.585
2.977LeuIle: 2.977 ± 0.634
5.954LeuLys: 5.954 ± 1.343
5.624LeuLeu: 5.624 ± 1.771
1.985LeuMet: 1.985 ± 1.488
5.293LeuAsn: 5.293 ± 1.305
4.3LeuPro: 4.3 ± 1.386
3.639LeuGln: 3.639 ± 1.068
5.954LeuArg: 5.954 ± 1.92
4.962LeuSer: 4.962 ± 1.074
3.97LeuThr: 3.97 ± 0.881
2.316LeuVal: 2.316 ± 0.774
1.654LeuTrp: 1.654 ± 0.885
1.323LeuTyr: 1.323 ± 0.434
0.0LeuXaa: 0.0 ± 0.0
Met
1.323MetAla: 1.323 ± 0.492
0.662MetCys: 0.662 ± 0.46
2.646MetAsp: 2.646 ± 1.129
1.654MetGlu: 1.654 ± 0.898
0.0MetPhe: 0.0 ± 0.0
1.654MetGly: 1.654 ± 0.594
1.323MetHis: 1.323 ± 0.651
1.323MetIle: 1.323 ± 0.453
1.985MetLys: 1.985 ± 0.711
2.646MetLeu: 2.646 ± 1.085
0.992MetMet: 0.992 ± 0.581
0.992MetAsn: 0.992 ± 0.683
1.985MetPro: 1.985 ± 0.499
0.662MetGln: 0.662 ± 0.369
0.0MetArg: 0.0 ± 0.0
1.654MetSer: 1.654 ± 0.634
0.331MetThr: 0.331 ± 0.368
2.977MetVal: 2.977 ± 0.388
0.331MetTrp: 0.331 ± 0.249
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.646AsnAla: 2.646 ± 0.797
0.331AsnCys: 0.331 ± 0.249
2.316AsnAsp: 2.316 ± 1.089
1.323AsnGlu: 1.323 ± 0.518
0.662AsnPhe: 0.662 ± 0.262
3.639AsnGly: 3.639 ± 1.474
0.0AsnHis: 0.0 ± 0.0
2.316AsnIle: 2.316 ± 0.6
2.316AsnLys: 2.316 ± 0.976
4.962AsnLeu: 4.962 ± 1.897
0.662AsnMet: 0.662 ± 0.5
2.646AsnAsn: 2.646 ± 0.724
3.639AsnPro: 3.639 ± 1.275
1.985AsnGln: 1.985 ± 1.001
3.639AsnArg: 3.639 ± 1.655
1.654AsnSer: 1.654 ± 0.75
2.977AsnThr: 2.977 ± 0.388
1.323AsnVal: 1.323 ± 0.448
0.662AsnTrp: 0.662 ± 0.389
1.654AsnTyr: 1.654 ± 0.312
0.0AsnXaa: 0.0 ± 0.0
Pro
4.3ProAla: 4.3 ± 1.529
0.331ProCys: 0.331 ± 0.368
2.977ProAsp: 2.977 ± 0.44
4.631ProGlu: 4.631 ± 1.37
0.662ProPhe: 0.662 ± 0.262
3.97ProGly: 3.97 ± 1.33
0.992ProHis: 0.992 ± 0.795
3.97ProIle: 3.97 ± 0.819
5.293ProLys: 5.293 ± 1.192
3.97ProLeu: 3.97 ± 1.17
1.985ProMet: 1.985 ± 0.433
1.323ProAsn: 1.323 ± 0.448
5.293ProPro: 5.293 ± 1.318
1.654ProGln: 1.654 ± 0.421
6.616ProArg: 6.616 ± 1.94
5.954ProSer: 5.954 ± 2.854
4.3ProThr: 4.3 ± 0.728
6.947ProVal: 6.947 ± 0.994
0.0ProTrp: 0.0 ± 0.0
0.662ProTyr: 0.662 ± 0.369
0.0ProXaa: 0.0 ± 0.0
Gln
1.985GlnAla: 1.985 ± 0.469
0.992GlnCys: 0.992 ± 0.334
1.985GlnAsp: 1.985 ± 0.721
1.654GlnGlu: 1.654 ± 0.709
2.646GlnPhe: 2.646 ± 0.512
3.308GlnGly: 3.308 ± 0.586
1.654GlnHis: 1.654 ± 0.542
0.662GlnIle: 0.662 ± 0.499
1.323GlnLys: 1.323 ± 0.748
1.985GlnLeu: 1.985 ± 0.358
0.0GlnMet: 0.0 ± 0.0
1.985GlnAsn: 1.985 ± 0.734
1.654GlnPro: 1.654 ± 0.771
1.654GlnGln: 1.654 ± 0.836
1.654GlnArg: 1.654 ± 0.451
2.977GlnSer: 2.977 ± 1.12
0.992GlnThr: 0.992 ± 0.495
3.308GlnVal: 3.308 ± 0.488
0.331GlnTrp: 0.331 ± 0.374
1.985GlnTyr: 1.985 ± 0.366
0.0GlnXaa: 0.0 ± 0.0
Arg
5.293ArgAla: 5.293 ± 0.845
0.331ArgCys: 0.331 ± 0.249
3.97ArgAsp: 3.97 ± 1.435
3.308ArgGlu: 3.308 ± 0.84
3.639ArgPhe: 3.639 ± 0.363
3.308ArgGly: 3.308 ± 1.678
0.331ArgHis: 0.331 ± 0.374
2.316ArgIle: 2.316 ± 0.627
3.308ArgLys: 3.308 ± 0.997
6.285ArgLeu: 6.285 ± 2.346
1.654ArgMet: 1.654 ± 0.754
4.962ArgAsn: 4.962 ± 3.071
6.285ArgPro: 6.285 ± 1.198
1.654ArgGln: 1.654 ± 0.486
15.547ArgArg: 15.547 ± 3.751
7.278ArgSer: 7.278 ± 1.598
6.616ArgThr: 6.616 ± 1.37
4.3ArgVal: 4.3 ± 1.213
0.331ArgTrp: 0.331 ± 0.249
2.646ArgTyr: 2.646 ± 0.326
0.0ArgXaa: 0.0 ± 0.0
Ser
3.97SerAla: 3.97 ± 0.734
0.992SerCys: 0.992 ± 0.716
2.977SerAsp: 2.977 ± 1.273
3.97SerGlu: 3.97 ± 0.881
2.646SerPhe: 2.646 ± 0.61
5.293SerGly: 5.293 ± 1.195
1.654SerHis: 1.654 ± 1.218
4.631SerIle: 4.631 ± 1.437
4.3SerLys: 4.3 ± 0.712
4.631SerLeu: 4.631 ± 1.676
2.646SerMet: 2.646 ± 1.013
1.323SerAsn: 1.323 ± 0.687
5.624SerPro: 5.624 ± 1.631
4.631SerGln: 4.631 ± 1.025
7.278SerArg: 7.278 ± 1.946
12.901SerSer: 12.901 ± 5.891
5.954SerThr: 5.954 ± 1.277
2.316SerVal: 2.316 ± 0.628
0.992SerTrp: 0.992 ± 0.542
3.97SerTyr: 3.97 ± 0.774
0.0SerXaa: 0.0 ± 0.0
Thr
3.97ThrAla: 3.97 ± 0.827
1.654ThrCys: 1.654 ± 0.688
1.654ThrAsp: 1.654 ± 0.421
3.639ThrGlu: 3.639 ± 0.686
2.316ThrPhe: 2.316 ± 0.75
3.639ThrGly: 3.639 ± 0.445
0.0ThrHis: 0.0 ± 0.0
2.646ThrIle: 2.646 ± 0.809
2.316ThrLys: 2.316 ± 0.794
4.631ThrLeu: 4.631 ± 1.244
0.992ThrMet: 0.992 ± 0.492
2.977ThrAsn: 2.977 ± 1.328
2.646ThrPro: 2.646 ± 1.963
0.992ThrGln: 0.992 ± 0.7
4.3ThrArg: 4.3 ± 1.563
6.947ThrSer: 6.947 ± 2.96
4.3ThrThr: 4.3 ± 1.08
5.954ThrVal: 5.954 ± 1.254
0.331ThrTrp: 0.331 ± 0.368
1.323ThrTyr: 1.323 ± 0.492
0.0ThrXaa: 0.0 ± 0.0
Val
6.616ValAla: 6.616 ± 1.499
1.323ValCys: 1.323 ± 0.825
3.639ValAsp: 3.639 ± 0.698
4.631ValGlu: 4.631 ± 1.074
3.308ValPhe: 3.308 ± 0.76
1.654ValGly: 1.654 ± 0.547
0.331ValHis: 0.331 ± 0.368
3.308ValIle: 3.308 ± 0.48
5.293ValLys: 5.293 ± 1.218
2.316ValLeu: 2.316 ± 0.444
1.985ValMet: 1.985 ± 0.667
1.654ValAsn: 1.654 ± 0.602
5.954ValPro: 5.954 ± 0.899
1.985ValGln: 1.985 ± 0.585
5.624ValArg: 5.624 ± 1.022
5.624ValSer: 5.624 ± 1.313
5.624ValThr: 5.624 ± 0.828
5.624ValVal: 5.624 ± 1.357
1.323ValTrp: 1.323 ± 0.63
2.646ValTyr: 2.646 ± 0.593
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.992TrpAsp: 0.992 ± 0.457
1.985TrpGlu: 1.985 ± 0.913
0.662TrpPhe: 0.662 ± 0.262
0.0TrpGly: 0.0 ± 0.0
0.662TrpHis: 0.662 ± 0.315
0.0TrpIle: 0.0 ± 0.0
0.662TrpLys: 0.662 ± 0.39
0.992TrpLeu: 0.992 ± 0.435
0.992TrpMet: 0.992 ± 0.456
0.992TrpAsn: 0.992 ± 0.457
1.323TrpPro: 1.323 ± 0.402
0.662TrpGln: 0.662 ± 0.262
0.992TrpArg: 0.992 ± 0.562
0.992TrpSer: 0.992 ± 0.596
0.662TrpThr: 0.662 ± 0.558
0.992TrpVal: 0.992 ± 0.54
0.0TrpTrp: 0.0 ± 0.0
0.331TrpTyr: 0.331 ± 0.249
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.662TyrAla: 0.662 ± 0.315
0.662TyrCys: 0.662 ± 0.421
0.662TyrAsp: 0.662 ± 0.262
1.654TyrGlu: 1.654 ± 0.75
1.985TyrPhe: 1.985 ± 0.807
2.646TyrGly: 2.646 ± 0.485
1.985TyrHis: 1.985 ± 0.585
2.316TyrIle: 2.316 ± 0.528
2.977TyrLys: 2.977 ± 0.699
2.316TyrLeu: 2.316 ± 0.811
1.323TyrMet: 1.323 ± 0.405
2.646TyrAsn: 2.646 ± 0.724
0.662TyrPro: 0.662 ± 0.315
0.0TyrGln: 0.0 ± 0.0
1.985TyrArg: 1.985 ± 0.643
2.977TyrSer: 2.977 ± 0.741
1.985TyrThr: 1.985 ± 0.675
2.646TyrVal: 2.646 ± 0.801
0.992TyrTrp: 0.992 ± 0.457
0.662TyrTyr: 0.662 ± 0.315
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.331XaaVal: 0.331 ± 0.249
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (3024 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski