Amino acid dipepetide frequency for Cercospora zeina

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.481AlaAla: 10.481 ± 0.062	1.129AlaCys: 1.129 ± 0.015	4.685AlaAsp: 4.685 ± 0.03	5.781AlaGlu: 5.781 ± 0.046	3.232AlaPhe: 3.232 ± 0.029	6.285AlaGly: 6.285 ± 0.042	2.079AlaHis: 2.079 ± 0.018	4.273AlaIle: 4.273 ± 0.033	4.495AlaLys: 4.495 ± 0.041	8.03AlaLeu: 8.03 ± 0.053	2.123AlaMet: 2.123 ± 0.02	3.221AlaAsn: 3.221 ± 0.024	5.343AlaPro: 5.343 ± 0.054	4.045AlaGln: 4.045 ± 0.031	5.556AlaArg: 5.556 ± 0.04	7.787AlaSer: 7.787 ± 0.051	5.851AlaThr: 5.851 ± 0.038	5.65AlaVal: 5.65 ± 0.039	1.222AlaTrp: 1.222 ± 0.019	2.31AlaTyr: 2.31 ± 0.025	0.001AlaXaa: 0.001 ± 0.0
Cys	1.015CysAla: 1.015 ± 0.015	0.259CysCys: 0.259 ± 0.008	0.652CysAsp: 0.652 ± 0.012	0.617CysGlu: 0.617 ± 0.012	0.523CysPhe: 0.523 ± 0.009	0.939CysGly: 0.939 ± 0.015	0.33CysHis: 0.33 ± 0.009	0.666CysIle: 0.666 ± 0.014	0.526CysLys: 0.526 ± 0.01	1.158CysLeu: 1.158 ± 0.02	0.27CysMet: 0.27 ± 0.008	0.422CysAsn: 0.422 ± 0.009	0.647CysPro: 0.647 ± 0.012	0.442CysGln: 0.442 ± 0.008	0.772CysArg: 0.772 ± 0.012	0.897CysSer: 0.897 ± 0.014	0.733CysThr: 0.733 ± 0.013	0.786CysVal: 0.786 ± 0.013	0.198CysTrp: 0.198 ± 0.006	0.359CysTyr: 0.359 ± 0.01	0.001CysXaa: 0.001 ± 0.0
Asp	5.354AspAla: 5.354 ± 0.034	0.642AspCys: 0.642 ± 0.012	4.517AspAsp: 4.517 ± 0.045	4.622AspGlu: 4.622 ± 0.035	2.228AspPhe: 2.228 ± 0.021	4.215AspGly: 4.215 ± 0.029	1.322AspHis: 1.322 ± 0.017	2.733AspIle: 2.733 ± 0.025	2.266AspLys: 2.266 ± 0.025	4.965AspLeu: 4.965 ± 0.03	1.308AspMet: 1.308 ± 0.017	1.776AspAsn: 1.776 ± 0.019	3.151AspPro: 3.151 ± 0.027	1.979AspGln: 1.979 ± 0.022	3.183AspArg: 3.183 ± 0.028	3.971AspSer: 3.971 ± 0.031	2.923AspThr: 2.923 ± 0.021	3.832AspVal: 3.832 ± 0.027	0.901AspTrp: 0.901 ± 0.013	1.551AspTyr: 1.551 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.694GluAla: 5.694 ± 0.049	0.604GluCys: 0.604 ± 0.011	4.304GluAsp: 4.304 ± 0.04	5.432GluGlu: 5.432 ± 0.056	1.788GluPhe: 1.788 ± 0.019	3.821GluGly: 3.821 ± 0.035	1.646GluHis: 1.646 ± 0.02	2.831GluIle: 2.831 ± 0.024	3.626GluLys: 3.626 ± 0.035	5.22GluLeu: 5.22 ± 0.036	1.465GluMet: 1.465 ± 0.016	2.126GluAsn: 2.126 ± 0.02	2.729GluPro: 2.729 ± 0.029	2.99GluGln: 2.99 ± 0.027	4.276GluArg: 4.276 ± 0.037	3.978GluSer: 3.978 ± 0.029	3.334GluThr: 3.334 ± 0.027	3.564GluVal: 3.564 ± 0.026	0.866GluTrp: 0.866 ± 0.013	1.625GluTyr: 1.625 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.274PheAla: 3.274 ± 0.029	0.535PheCys: 0.535 ± 0.011	2.283PheAsp: 2.283 ± 0.021	2.118PheGlu: 2.118 ± 0.024	1.464PhePhe: 1.464 ± 0.026	2.815PheGly: 2.815 ± 0.03	0.87PheHis: 0.87 ± 0.013	1.515PheIle: 1.515 ± 0.022	1.381PheLys: 1.381 ± 0.018	3.056PheLeu: 3.056 ± 0.03	0.748PheMet: 0.748 ± 0.012	1.3PheAsn: 1.3 ± 0.016	1.792PhePro: 1.792 ± 0.02	1.324PheGln: 1.324 ± 0.017	1.876PheArg: 1.876 ± 0.02	2.662PheSer: 2.662 ± 0.026	2.089PheThr: 2.089 ± 0.019	2.337PheVal: 2.337 ± 0.025	0.622PheTrp: 0.622 ± 0.01	1.003PheTyr: 1.003 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.731GlyAla: 5.731 ± 0.044	0.834GlyCys: 0.834 ± 0.014	3.683GlyAsp: 3.683 ± 0.025	3.781GlyGlu: 3.781 ± 0.027	2.659GlyPhe: 2.659 ± 0.027	6.099GlyGly: 6.099 ± 0.056	1.775GlyHis: 1.775 ± 0.017	3.337GlyIle: 3.337 ± 0.03	3.548GlyLys: 3.548 ± 0.032	5.893GlyLeu: 5.893 ± 0.038	1.69GlyMet: 1.69 ± 0.023	2.557GlyAsn: 2.557 ± 0.027	3.304GlyPro: 3.304 ± 0.032	2.713GlyGln: 2.713 ± 0.025	4.281GlyArg: 4.281 ± 0.036	5.649GlySer: 5.649 ± 0.042	4.134GlyThr: 4.134 ± 0.034	4.265GlyVal: 4.265 ± 0.036	1.114GlyTrp: 1.114 ± 0.016	2.071GlyTyr: 2.071 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	2.254HisAla: 2.254 ± 0.024	0.36HisCys: 0.36 ± 0.009	1.543HisAsp: 1.543 ± 0.019	1.499HisGlu: 1.499 ± 0.017	0.968HisPhe: 0.968 ± 0.013	1.844HisGly: 1.844 ± 0.022	0.976HisHis: 0.976 ± 0.017	1.153HisIle: 1.153 ± 0.015	0.981HisLys: 0.981 ± 0.015	2.227HisLeu: 2.227 ± 0.023	0.514HisMet: 0.514 ± 0.01	0.873HisAsn: 0.873 ± 0.013	1.625HisPro: 1.625 ± 0.017	1.017HisGln: 1.017 ± 0.015	1.661HisArg: 1.661 ± 0.02	1.932HisSer: 1.932 ± 0.022	1.338HisThr: 1.338 ± 0.015	1.622HisVal: 1.622 ± 0.018	0.364HisTrp: 0.364 ± 0.009	0.689HisTyr: 0.689 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.355IleAla: 4.355 ± 0.033	0.703IleCys: 0.703 ± 0.013	2.817IleAsp: 2.817 ± 0.024	2.78IleGlu: 2.78 ± 0.024	1.769IlePhe: 1.769 ± 0.02	3.047IleGly: 3.047 ± 0.032	1.068IleHis: 1.068 ± 0.013	2.152IleIle: 2.152 ± 0.024	2.008IleLys: 2.008 ± 0.022	3.97IleLeu: 3.97 ± 0.035	0.979IleMet: 0.979 ± 0.014	1.667IleAsn: 1.667 ± 0.019	2.689IlePro: 2.689 ± 0.022	1.661IleGln: 1.661 ± 0.019	2.662IleArg: 2.662 ± 0.024	3.424IleSer: 3.424 ± 0.026	2.689IleThr: 2.689 ± 0.024	3.073IleVal: 3.073 ± 0.032	0.681IleTrp: 0.681 ± 0.012	1.259IleTyr: 1.259 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.513LysAla: 4.513 ± 0.032	0.48LysCys: 0.48 ± 0.009	2.812LysAsp: 2.812 ± 0.027	3.266LysGlu: 3.266 ± 0.034	1.367LysPhe: 1.367 ± 0.018	2.874LysGly: 2.874 ± 0.029	1.241LysHis: 1.241 ± 0.016	2.115LysIle: 2.115 ± 0.024	3.418LysLys: 3.418 ± 0.047	3.999LysLeu: 3.999 ± 0.032	1.027LysMet: 1.027 ± 0.016	1.658LysAsn: 1.658 ± 0.019	2.67LysPro: 2.67 ± 0.029	2.121LysGln: 2.121 ± 0.024	3.618LysArg: 3.618 ± 0.034	3.39LysSer: 3.39 ± 0.028	2.797LysThr: 2.797 ± 0.025	2.749LysVal: 2.749 ± 0.026	0.69LysTrp: 0.69 ± 0.012	1.311LysTyr: 1.311 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.0LeuAla: 8.0 ± 0.054	1.16LeuCys: 1.16 ± 0.017	4.958LeuAsp: 4.958 ± 0.039	5.275LeuGlu: 5.275 ± 0.037	2.998LeuPhe: 2.998 ± 0.03	5.598LeuGly: 5.598 ± 0.038	2.347LeuHis: 2.347 ± 0.022	3.567LeuIle: 3.567 ± 0.03	3.944LeuLys: 3.944 ± 0.033	7.919LeuLeu: 7.919 ± 0.064	1.687LeuMet: 1.687 ± 0.02	2.923LeuAsn: 2.923 ± 0.021	5.534LeuPro: 5.534 ± 0.039	3.987LeuGln: 3.987 ± 0.031	5.815LeuArg: 5.815 ± 0.039	6.694LeuSer: 6.694 ± 0.044	4.667LeuThr: 4.667 ± 0.031	5.078LeuVal: 5.078 ± 0.039	1.125LeuTrp: 1.125 ± 0.015	2.198LeuTyr: 2.198 ± 0.023	0.001LeuXaa: 0.001 ± 0.0
Met	2.281MetAla: 2.281 ± 0.021	0.261MetCys: 0.261 ± 0.007	1.179MetAsp: 1.179 ± 0.016	1.214MetGlu: 1.214 ± 0.015	0.731MetPhe: 0.731 ± 0.012	1.421MetGly: 1.421 ± 0.02	0.577MetHis: 0.577 ± 0.011	0.947MetIle: 0.947 ± 0.015	1.008MetLys: 1.008 ± 0.013	1.912MetLeu: 1.912 ± 0.022	0.567MetMet: 0.567 ± 0.013	0.787MetAsn: 0.787 ± 0.014	1.433MetPro: 1.433 ± 0.015	1.001MetGln: 1.001 ± 0.017	1.361MetArg: 1.361 ± 0.016	1.864MetSer: 1.864 ± 0.021	1.283MetThr: 1.283 ± 0.017	1.207MetVal: 1.207 ± 0.015	0.273MetTrp: 0.273 ± 0.007	0.536MetTyr: 0.536 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.491AsnAla: 3.491 ± 0.031	0.437AsnCys: 0.437 ± 0.012	2.043AsnAsp: 2.043 ± 0.021	2.065AsnGlu: 2.065 ± 0.023	1.344AsnPhe: 1.344 ± 0.017	3.232AsnGly: 3.232 ± 0.034	0.834AsnHis: 0.834 ± 0.013	1.815AsnIle: 1.815 ± 0.019	1.496AsnLys: 1.496 ± 0.019	2.94AsnLeu: 2.94 ± 0.023	0.845AsnMet: 0.845 ± 0.012	1.509AsnAsn: 1.509 ± 0.024	2.156AsnPro: 2.156 ± 0.023	1.248AsnGln: 1.248 ± 0.017	1.834AsnArg: 1.834 ± 0.018	2.579AsnSer: 2.579 ± 0.024	2.224AsnThr: 2.224 ± 0.021	2.387AsnVal: 2.387 ± 0.024	0.534AsnTrp: 0.534 ± 0.011	0.988AsnTyr: 0.988 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	5.871ProAla: 5.871 ± 0.052	0.525ProCys: 0.525 ± 0.013	3.113ProAsp: 3.113 ± 0.025	3.683ProGlu: 3.683 ± 0.036	1.919ProPhe: 1.919 ± 0.018	3.987ProGly: 3.987 ± 0.04	1.42ProHis: 1.42 ± 0.02	2.388ProIle: 2.388 ± 0.018	2.638ProLys: 2.638 ± 0.028	4.508ProLeu: 4.508 ± 0.034	1.073ProMet: 1.073 ± 0.014	2.191ProAsn: 2.191 ± 0.022	5.381ProPro: 5.381 ± 0.074	2.674ProGln: 2.674 ± 0.027	3.564ProArg: 3.564 ± 0.036	5.688ProSer: 5.688 ± 0.049	4.08ProThr: 4.08 ± 0.04	3.406ProVal: 3.406 ± 0.028	0.706ProTrp: 0.706 ± 0.012	1.49ProTyr: 1.49 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.92GlnAla: 3.92 ± 0.03	0.478GlnCys: 0.478 ± 0.011	2.273GlnAsp: 2.273 ± 0.018	2.497GlnGlu: 2.497 ± 0.025	1.23GlnPhe: 1.23 ± 0.016	2.403GlnGly: 2.403 ± 0.025	1.361GlnHis: 1.361 ± 0.019	1.866GlnIle: 1.866 ± 0.02	2.094GlnLys: 2.094 ± 0.023	3.598GlnLeu: 3.598 ± 0.03	0.928GlnMet: 0.928 ± 0.015	1.653GlnAsn: 1.653 ± 0.02	2.757GlnPro: 2.757 ± 0.035	3.148GlnGln: 3.148 ± 0.049	3.034GlnArg: 3.034 ± 0.03	3.277GlnSer: 3.277 ± 0.03	2.483GlnThr: 2.483 ± 0.023	2.199GlnVal: 2.199 ± 0.024	0.605GlnTrp: 0.605 ± 0.012	1.259GlnTyr: 1.259 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	5.298ArgAla: 5.298 ± 0.034	0.74ArgCys: 0.74 ± 0.014	3.521ArgAsp: 3.521 ± 0.032	3.99ArgGlu: 3.99 ± 0.038	2.042ArgPhe: 2.042 ± 0.02	3.821ArgGly: 3.821 ± 0.036	1.706ArgHis: 1.706 ± 0.017	2.861ArgIle: 2.861 ± 0.023	3.711ArgLys: 3.711 ± 0.031	5.37ArgLeu: 5.37 ± 0.034	1.41ArgMet: 1.41 ± 0.018	2.342ArgAsn: 2.342 ± 0.022	3.808ArgPro: 3.808 ± 0.04	2.881ArgGln: 2.881 ± 0.024	5.284ArgArg: 5.284 ± 0.048	5.053ArgSer: 5.053 ± 0.043	3.591ArgThr: 3.591 ± 0.029	3.326ArgVal: 3.326 ± 0.026	0.928ArgTrp: 0.928 ± 0.013	1.612ArgTyr: 1.612 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	7.267SerAla: 7.267 ± 0.054	0.881SerCys: 0.881 ± 0.012	4.105SerAsp: 4.105 ± 0.031	4.009SerGlu: 4.009 ± 0.032	2.719SerPhe: 2.719 ± 0.023	5.607SerGly: 5.607 ± 0.041	1.953SerHis: 1.953 ± 0.022	3.644SerIle: 3.644 ± 0.03	3.621SerLys: 3.621 ± 0.031	6.484SerLeu: 6.484 ± 0.038	1.704SerMet: 1.704 ± 0.018	2.947SerAsn: 2.947 ± 0.027	5.332SerPro: 5.332 ± 0.049	3.218SerGln: 3.218 ± 0.03	5.067SerArg: 5.067 ± 0.036	8.499SerSer: 8.499 ± 0.075	5.653SerThr: 5.653 ± 0.053	4.348SerVal: 4.348 ± 0.029	1.079SerTrp: 1.079 ± 0.015	1.937SerTyr: 1.937 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.809ThrAla: 5.809 ± 0.04	0.77ThrCys: 0.77 ± 0.014	2.835ThrAsp: 2.835 ± 0.025	3.085ThrGlu: 3.085 ± 0.027	2.248ThrPhe: 2.248 ± 0.023	4.223ThrGly: 4.223 ± 0.036	1.321ThrHis: 1.321 ± 0.016	2.999ThrIle: 2.999 ± 0.029	2.652ThrLys: 2.652 ± 0.025	5.055ThrLeu: 5.055 ± 0.035	1.259ThrMet: 1.259 ± 0.016	2.2ThrAsn: 2.2 ± 0.023	4.336ThrPro: 4.336 ± 0.037	2.199ThrGln: 2.199 ± 0.022	3.362ThrArg: 3.362 ± 0.026	5.449ThrSer: 5.449 ± 0.04	4.687ThrThr: 4.687 ± 0.056	3.587ThrVal: 3.587 ± 0.035	0.853ThrTrp: 0.853 ± 0.013	1.599ThrTyr: 1.599 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.537ValAla: 5.537 ± 0.039	0.806ValCys: 0.806 ± 0.013	3.622ValAsp: 3.622 ± 0.028	3.871ValGlu: 3.871 ± 0.031	2.229ValPhe: 2.229 ± 0.025	3.945ValGly: 3.945 ± 0.032	1.469ValHis: 1.469 ± 0.015	2.616ValIle: 2.616 ± 0.026	2.905ValLys: 2.905 ± 0.022	5.389ValLeu: 5.389 ± 0.039	1.278ValMet: 1.278 ± 0.015	2.168ValAsn: 2.168 ± 0.02	3.596ValPro: 3.596 ± 0.028	2.61ValGln: 2.61 ± 0.023	3.535ValArg: 3.535 ± 0.027	4.315ValSer: 4.315 ± 0.033	3.452ValThr: 3.452 ± 0.03	4.218ValVal: 4.218 ± 0.036	0.841ValTrp: 0.841 ± 0.014	1.605ValTyr: 1.605 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.111TrpAla: 1.111 ± 0.016	0.202TrpCys: 0.202 ± 0.007	0.837TrpAsp: 0.837 ± 0.013	0.786TrpGlu: 0.786 ± 0.014	0.526TrpPhe: 0.526 ± 0.011	0.813TrpGly: 0.813 ± 0.013	0.391TrpHis: 0.391 ± 0.009	0.712TrpIle: 0.712 ± 0.013	0.777TrpLys: 0.777 ± 0.012	1.34TrpLeu: 1.34 ± 0.019	0.357TrpMet: 0.357 ± 0.009	0.621TrpAsn: 0.621 ± 0.012	0.624TrpPro: 0.624 ± 0.013	0.676TrpGln: 0.676 ± 0.011	0.997TrpArg: 0.997 ± 0.018	1.053TrpSer: 1.053 ± 0.016	0.965TrpThr: 0.965 ± 0.014	0.795TrpVal: 0.795 ± 0.013	0.257TrpTrp: 0.257 ± 0.008	0.442TrpTyr: 0.442 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.326TyrAla: 2.326 ± 0.025	0.404TyrCys: 0.404 ± 0.01	1.657TyrAsp: 1.657 ± 0.017	1.549TyrGlu: 1.549 ± 0.018	1.08TyrPhe: 1.08 ± 0.014	2.13TyrGly: 2.13 ± 0.023	0.754TyrHis: 0.754 ± 0.012	1.263TyrIle: 1.263 ± 0.015	1.022TyrLys: 1.022 ± 0.017	2.441TyrLeu: 2.441 ± 0.027	0.611TyrMet: 0.611 ± 0.01	1.062TyrAsn: 1.062 ± 0.016	1.398TyrPro: 1.398 ± 0.019	1.128TyrGln: 1.128 ± 0.018	1.557TyrArg: 1.557 ± 0.018	1.913TyrSer: 1.913 ± 0.022	1.555TyrThr: 1.555 ± 0.019	1.576TyrVal: 1.576 ± 0.021	0.421TyrTrp: 0.421 ± 0.01	0.897TyrTyr: 0.897 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.028XaaXaa: 0.028 ± 0.014

Statistics based on 10192 proteins (5190240 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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