Amino acid dipepetide frequency for Leishmania RNA virus 1 - 1 (isolate Leishmania guyanensis) (LRV-1-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.711AlaAla: 7.711 ± 1.226
3.559AlaCys: 3.559 ± 1.15
5.338AlaAsp: 5.338 ± 0.949
1.186AlaGlu: 1.186 ± 0.149
0.593AlaPhe: 0.593 ± 0.479
6.524AlaGly: 6.524 ± 1.086
2.966AlaHis: 2.966 ± 0.439
4.152AlaIle: 4.152 ± 1.849
2.372AlaLys: 2.372 ± 0.803
11.269AlaLeu: 11.269 ± 3.505
3.559AlaMet: 3.559 ± 1.049
4.152AlaAsn: 4.152 ± 1.62
1.186AlaPro: 1.186 ± 0.958
2.966AlaGln: 2.966 ± 1.214
6.524AlaArg: 6.524 ± 1.834
5.931AlaSer: 5.931 ± 1.94
6.524AlaThr: 6.524 ± 1.086
8.304AlaVal: 8.304 ± 1.034
0.593AlaTrp: 0.593 ± 0.479
2.372AlaTyr: 2.372 ± 0.803
0.0AlaXaa: 0.0 ± 0.0
Cys
2.966CysAla: 2.966 ± 0.439
1.186CysCys: 1.186 ± 0.831
4.152CysAsp: 4.152 ± 1.62
1.186CysGlu: 1.186 ± 0.149
0.0CysPhe: 0.0 ± 0.0
2.966CysGly: 2.966 ± 0.69
0.593CysHis: 0.593 ± 0.479
2.372CysIle: 2.372 ± 1.337
0.0CysLys: 0.0 ± 0.0
2.966CysLeu: 2.966 ± 0.439
1.186CysMet: 1.186 ± 0.958
0.593CysAsn: 0.593 ± 0.479
0.593CysPro: 0.593 ± 0.416
1.186CysGln: 1.186 ± 0.149
1.186CysArg: 1.186 ± 0.831
1.779CysSer: 1.779 ± 1.391
1.186CysThr: 1.186 ± 0.149
2.372CysVal: 2.372 ± 0.803
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.931AspAla: 5.931 ± 3.048
0.593AspCys: 0.593 ± 0.479
3.559AspAsp: 3.559 ± 1.627
1.779AspGlu: 1.779 ± 0.575
2.372AspPhe: 2.372 ± 0.298
3.559AspGly: 3.559 ± 2.002
0.593AspHis: 0.593 ± 0.416
5.931AspIle: 5.931 ± 0.745
2.372AspLys: 2.372 ± 1.047
2.372AspLeu: 2.372 ± 0.803
0.0AspMet: 0.0 ± 0.0
1.186AspAsn: 1.186 ± 0.149
2.966AspPro: 2.966 ± 0.69
1.779AspGln: 1.779 ± 1.391
1.779AspArg: 1.779 ± 1.559
4.152AspSer: 4.152 ± 1.15
2.966AspThr: 2.966 ± 0.69
3.559AspVal: 3.559 ± 0.447
0.0AspTrp: 0.0 ± 0.0
3.559AspTyr: 3.559 ± 1.372
0.0AspXaa: 0.0 ± 0.0
Glu
3.559GluAla: 3.559 ± 0.801
0.593GluCys: 0.593 ± 0.416
2.372GluAsp: 2.372 ± 0.803
3.559GluGlu: 3.559 ± 1.627
2.372GluPhe: 2.372 ± 0.298
3.559GluGly: 3.559 ± 0.447
1.779GluHis: 1.779 ± 1.247
1.779GluIle: 1.779 ± 0.575
2.966GluLys: 2.966 ± 2.078
5.931GluLeu: 5.931 ± 1.308
1.186GluMet: 1.186 ± 0.149
1.779GluAsn: 1.779 ± 0.401
2.372GluPro: 2.372 ± 1.915
1.779GluGln: 1.779 ± 1.247
1.779GluArg: 1.779 ± 0.401
2.372GluSer: 2.372 ± 1.337
1.779GluThr: 1.779 ± 0.401
3.559GluVal: 3.559 ± 0.447
1.779GluTrp: 1.779 ± 1.734
1.779GluTyr: 1.779 ± 0.401
0.0GluXaa: 0.0 ± 0.0
Phe
2.372PheAla: 2.372 ± 0.803
2.372PheCys: 2.372 ± 1.461
1.779PheAsp: 1.779 ± 0.575
2.966PheGlu: 2.966 ± 0.439
1.186PhePhe: 1.186 ± 0.831
1.186PheGly: 1.186 ± 0.149
1.186PheHis: 1.186 ± 0.149
1.186PheIle: 1.186 ± 0.149
0.0PheLys: 0.0 ± 0.0
1.186PheLeu: 1.186 ± 0.149
0.0PheMet: 0.0 ± 0.0
2.966PheAsn: 2.966 ± 1.524
0.0PhePro: 0.0 ± 0.0
0.593PheGln: 0.593 ± 0.479
1.779PheArg: 1.779 ± 1.437
2.966PheSer: 2.966 ± 1.214
1.779PheThr: 1.779 ± 0.575
1.186PheVal: 1.186 ± 0.149
1.186PheTrp: 1.186 ± 0.149
0.593PheTyr: 0.593 ± 0.479
0.0PheXaa: 0.0 ± 0.0
Gly
4.745GlyAla: 4.745 ± 1.261
2.372GlyCys: 2.372 ± 0.298
3.559GlyAsp: 3.559 ± 1.976
4.745GlyGlu: 4.745 ± 0.596
1.779GlyPhe: 1.779 ± 0.401
1.779GlyGly: 1.779 ± 1.247
2.372GlyHis: 2.372 ± 0.803
3.559GlyIle: 3.559 ± 1.194
1.779GlyLys: 1.779 ± 0.401
4.152GlyLeu: 4.152 ± 0.816
2.372GlyMet: 2.372 ± 1.337
2.966GlyAsn: 2.966 ± 0.69
1.186GlyPro: 1.186 ± 0.149
3.559GlyGln: 3.559 ± 0.447
2.966GlyArg: 2.966 ± 1.268
3.559GlySer: 3.559 ± 0.801
2.966GlyThr: 2.966 ± 0.69
4.745GlyVal: 4.745 ± 2.157
0.593GlyTrp: 0.593 ± 0.416
5.338GlyTyr: 5.338 ± 0.949
0.0GlyXaa: 0.0 ± 0.0
His
3.559HisAla: 3.559 ± 0.447
0.593HisCys: 0.593 ± 0.416
0.0HisAsp: 0.0 ± 0.0
0.593HisGlu: 0.593 ± 0.416
0.593HisPhe: 0.593 ± 0.479
1.779HisGly: 1.779 ± 0.401
0.593HisHis: 0.593 ± 0.416
1.779HisIle: 1.779 ± 0.575
1.779HisLys: 1.779 ± 1.437
1.779HisLeu: 1.779 ± 0.575
0.593HisMet: 0.593 ± 0.416
2.372HisAsn: 2.372 ± 0.803
1.186HisPro: 1.186 ± 0.149
0.0HisGln: 0.0 ± 0.0
1.779HisArg: 1.779 ± 1.247
2.966HisSer: 2.966 ± 1.524
2.372HisThr: 2.372 ± 1.662
4.152HisVal: 4.152 ± 0.816
0.0HisTrp: 0.0 ± 0.0
1.779HisTyr: 1.779 ± 0.575
0.0HisXaa: 0.0 ± 0.0
Ile
6.524IleAla: 6.524 ± 1.086
1.779IleCys: 1.779 ± 1.559
2.966IleAsp: 2.966 ± 1.67
5.338IleGlu: 5.338 ± 1.04
1.186IlePhe: 1.186 ± 0.958
1.779IleGly: 1.779 ± 0.401
0.593IleHis: 0.593 ± 0.416
3.559IleIle: 3.559 ± 0.447
2.966IleLys: 2.966 ± 1.214
5.931IleLeu: 5.931 ± 0.878
1.186IleMet: 1.186 ± 0.831
3.559IleAsn: 3.559 ± 0.801
1.779IlePro: 1.779 ± 0.401
1.779IleGln: 1.779 ± 0.401
2.966IleArg: 2.966 ± 0.69
2.966IleSer: 2.966 ± 1.214
1.779IleThr: 1.779 ± 0.401
1.779IleVal: 1.779 ± 1.559
1.779IleTrp: 1.779 ± 0.575
2.966IleTyr: 2.966 ± 0.69
0.0IleXaa: 0.0 ± 0.0
Lys
2.372LysAla: 2.372 ± 1.734
1.779LysCys: 1.779 ± 1.247
0.593LysAsp: 0.593 ± 0.416
2.372LysGlu: 2.372 ± 0.803
0.0LysPhe: 0.0 ± 0.0
2.372LysGly: 2.372 ± 1.662
1.779LysHis: 1.779 ± 0.575
2.372LysIle: 2.372 ± 0.803
2.966LysLys: 2.966 ± 0.439
4.152LysLeu: 4.152 ± 1.199
1.779LysMet: 1.779 ± 0.401
1.186LysAsn: 1.186 ± 0.149
1.186LysPro: 1.186 ± 0.149
0.593LysGln: 0.593 ± 0.416
2.372LysArg: 2.372 ± 1.047
1.779LysSer: 1.779 ± 0.401
3.559LysThr: 3.559 ± 1.627
4.152LysVal: 4.152 ± 0.816
0.0LysTrp: 0.0 ± 0.0
0.593LysTyr: 0.593 ± 0.479
0.0LysXaa: 0.0 ± 0.0
Leu
9.49LeuAla: 9.49 ± 1.972
1.186LeuCys: 1.186 ± 0.958
5.931LeuAsp: 5.931 ± 1.308
3.559LeuGlu: 3.559 ± 0.447
4.152LeuPhe: 4.152 ± 1.62
3.559LeuGly: 3.559 ± 0.447
2.372LeuHis: 2.372 ± 1.047
4.152LeuIle: 4.152 ± 0.519
3.559LeuLys: 3.559 ± 1.627
8.304LeuLeu: 8.304 ± 2.658
4.152LeuMet: 4.152 ± 2.041
7.117LeuAsn: 7.117 ± 2.755
5.931LeuPro: 5.931 ± 1.597
2.372LeuGln: 2.372 ± 0.298
5.931LeuArg: 5.931 ± 1.232
7.711LeuSer: 7.711 ± 1.226
4.745LeuThr: 4.745 ± 1.295
3.559LeuVal: 3.559 ± 1.194
2.372LeuTrp: 2.372 ± 1.662
2.372LeuTyr: 2.372 ± 0.298
0.0LeuXaa: 0.0 ± 0.0
Met
2.966MetAla: 2.966 ± 0.439
0.593MetCys: 0.593 ± 0.416
1.779MetAsp: 1.779 ± 0.575
1.779MetGlu: 1.779 ± 1.247
0.593MetPhe: 0.593 ± 0.479
0.593MetGly: 0.593 ± 0.416
1.779MetHis: 1.779 ± 0.575
0.593MetIle: 0.593 ± 0.479
0.593MetLys: 0.593 ± 0.416
2.966MetLeu: 2.966 ± 0.439
1.779MetMet: 1.779 ± 0.575
1.186MetAsn: 1.186 ± 0.149
3.559MetPro: 3.559 ± 1.372
1.186MetGln: 1.186 ± 0.831
0.593MetArg: 0.593 ± 0.479
4.152MetSer: 4.152 ± 1.849
1.779MetThr: 1.779 ± 1.437
2.372MetVal: 2.372 ± 1.734
0.593MetTrp: 0.593 ± 0.416
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.966AsnAla: 2.966 ± 1.214
1.186AsnCys: 1.186 ± 0.831
1.186AsnAsp: 1.186 ± 0.149
2.372AsnGlu: 2.372 ± 0.803
0.593AsnPhe: 0.593 ± 0.416
2.372AsnGly: 2.372 ± 0.803
1.779AsnHis: 1.779 ± 0.401
2.372AsnIle: 2.372 ± 0.298
2.372AsnLys: 2.372 ± 1.047
2.372AsnLeu: 2.372 ± 0.803
0.0AsnMet: 0.0 ± 0.0
1.779AsnAsn: 1.779 ± 0.401
2.966AsnPro: 2.966 ± 0.69
1.779AsnGln: 1.779 ± 1.247
5.338AsnArg: 5.338 ± 0.949
5.338AsnSer: 5.338 ± 1.112
3.559AsnThr: 3.559 ± 1.15
5.931AsnVal: 5.931 ± 2.194
0.593AsnTrp: 0.593 ± 0.416
2.372AsnTyr: 2.372 ± 0.298
0.0AsnXaa: 0.0 ± 0.0
Pro
1.779ProAla: 1.779 ± 0.575
1.186ProCys: 1.186 ± 0.831
0.593ProAsp: 0.593 ± 0.479
3.559ProGlu: 3.559 ± 1.15
0.593ProPhe: 0.593 ± 0.479
2.966ProGly: 2.966 ± 0.439
1.779ProHis: 1.779 ± 1.437
2.966ProIle: 2.966 ± 0.439
0.593ProLys: 0.593 ± 0.416
2.966ProLeu: 2.966 ± 1.524
2.372ProMet: 2.372 ± 1.461
4.152ProAsn: 4.152 ± 0.816
0.593ProPro: 0.593 ± 0.416
2.372ProGln: 2.372 ± 0.298
1.186ProArg: 1.186 ± 0.149
2.966ProSer: 2.966 ± 1.67
2.966ProThr: 2.966 ± 1.67
3.559ProVal: 3.559 ± 1.627
0.593ProTrp: 0.593 ± 0.479
1.779ProTyr: 1.779 ± 0.401
0.0ProXaa: 0.0 ± 0.0
Gln
2.966GlnAla: 2.966 ± 0.69
0.593GlnCys: 0.593 ± 0.416
0.0GlnAsp: 0.0 ± 0.0
0.593GlnGlu: 0.593 ± 0.416
1.186GlnPhe: 1.186 ± 0.958
1.186GlnGly: 1.186 ± 0.149
4.152GlnHis: 4.152 ± 0.519
0.0GlnIle: 0.0 ± 0.0
2.372GlnLys: 2.372 ± 1.662
2.372GlnLeu: 2.372 ± 0.803
1.779GlnMet: 1.779 ± 0.575
1.186GlnAsn: 1.186 ± 0.831
2.966GlnPro: 2.966 ± 1.524
1.186GlnGln: 1.186 ± 0.149
1.186GlnArg: 1.186 ± 0.831
1.779GlnSer: 1.779 ± 0.401
0.593GlnThr: 0.593 ± 0.416
2.966GlnVal: 2.966 ± 2.078
1.186GlnTrp: 1.186 ± 1.482
1.186GlnTyr: 1.186 ± 0.149
0.0GlnXaa: 0.0 ± 0.0
Arg
5.338ArgAla: 5.338 ± 1.718
1.779ArgCys: 1.779 ± 1.437
1.186ArgAsp: 1.186 ± 0.149
1.779ArgGlu: 1.779 ± 0.575
2.372ArgPhe: 2.372 ± 1.047
4.152ArgGly: 4.152 ± 1.261
2.966ArgHis: 2.966 ± 0.69
5.931ArgIle: 5.931 ± 0.878
2.966ArgLys: 2.966 ± 0.439
8.304ArgLeu: 8.304 ± 1.038
0.0ArgMet: 0.0 ± 0.0
2.372ArgAsn: 2.372 ± 1.047
2.966ArgPro: 2.966 ± 1.214
0.593ArgGln: 0.593 ± 0.416
4.745ArgArg: 4.745 ± 1.052
3.559ArgSer: 3.559 ± 1.194
1.779ArgThr: 1.779 ± 0.575
4.152ArgVal: 4.152 ± 0.519
1.779ArgTrp: 1.779 ± 1.559
2.966ArgTyr: 2.966 ± 0.439
0.0ArgXaa: 0.0 ± 0.0
Ser
6.524SerAla: 6.524 ± 2.667
2.966SerCys: 2.966 ± 0.69
7.117SerAsp: 7.117 ± 2.299
1.779SerGlu: 1.779 ± 0.401
2.966SerPhe: 2.966 ± 1.214
5.338SerGly: 5.338 ± 2.015
1.779SerHis: 1.779 ± 0.401
1.186SerIle: 1.186 ± 0.958
4.152SerLys: 4.152 ± 1.261
6.524SerLeu: 6.524 ± 4.024
3.559SerMet: 3.559 ± 1.627
2.966SerAsn: 2.966 ± 0.439
1.186SerPro: 1.186 ± 1.558
3.559SerGln: 3.559 ± 0.801
4.745SerArg: 4.745 ± 2.157
7.117SerSer: 7.117 ± 2.745
5.338SerThr: 5.338 ± 4.174
3.559SerVal: 3.559 ± 0.801
1.186SerTrp: 1.186 ± 0.831
2.966SerTyr: 2.966 ± 0.69
0.0SerXaa: 0.0 ± 0.0
Thr
5.931ThrAla: 5.931 ± 3.599
0.593ThrCys: 0.593 ± 0.479
0.593ThrAsp: 0.593 ± 0.479
3.559ThrGlu: 3.559 ± 1.627
1.779ThrPhe: 1.779 ± 1.391
4.745ThrGly: 4.745 ± 3.402
0.0ThrHis: 0.0 ± 0.0
2.372ThrIle: 2.372 ± 0.298
1.186ThrLys: 1.186 ± 0.149
7.117ThrLeu: 7.117 ± 3.254
1.186ThrMet: 1.186 ± 0.958
2.966ThrAsn: 2.966 ± 1.214
2.966ThrPro: 2.966 ± 1.524
1.779ThrGln: 1.779 ± 1.437
4.745ThrArg: 4.745 ± 1.261
7.117ThrSer: 7.117 ± 0.95
4.745ThrThr: 4.745 ± 2.958
3.559ThrVal: 3.559 ± 1.976
0.0ThrTrp: 0.0 ± 0.0
1.779ThrTyr: 1.779 ± 0.401
0.0ThrXaa: 0.0 ± 0.0
Val
5.931ValAla: 5.931 ± 1.232
1.186ValCys: 1.186 ± 0.149
4.745ValAsp: 4.745 ± 1.295
4.745ValGlu: 4.745 ± 2.157
1.779ValPhe: 1.779 ± 0.401
4.152ValGly: 4.152 ± 1.15
1.186ValHis: 1.186 ± 0.149
5.931ValIle: 5.931 ± 1.308
2.372ValLys: 2.372 ± 0.803
6.524ValLeu: 6.524 ± 1.086
2.966ValMet: 2.966 ± 1.234
2.966ValAsn: 2.966 ± 0.439
2.372ValPro: 2.372 ± 1.047
1.186ValGln: 1.186 ± 0.149
5.931ValArg: 5.931 ± 2.427
3.559ValSer: 3.559 ± 1.627
5.338ValThr: 5.338 ± 1.724
5.931ValVal: 5.931 ± 0.745
0.0ValTrp: 0.0 ± 0.0
3.559ValTyr: 3.559 ± 1.627
0.0ValXaa: 0.0 ± 0.0
Trp
1.186TrpAla: 1.186 ± 0.831
0.0TrpCys: 0.0 ± 0.0
1.779TrpAsp: 1.779 ± 0.575
1.186TrpGlu: 1.186 ± 1.482
0.593TrpPhe: 0.593 ± 0.416
2.372TrpGly: 2.372 ± 1.461
0.0TrpHis: 0.0 ± 0.0
0.593TrpIle: 0.593 ± 0.416
0.593TrpLys: 0.593 ± 0.416
1.186TrpLeu: 1.186 ± 0.149
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.593TrpPro: 0.593 ± 1.52
0.593TrpGln: 0.593 ± 0.416
1.186TrpArg: 1.186 ± 0.149
0.593TrpSer: 0.593 ± 0.416
0.593TrpThr: 0.593 ± 0.479
1.779TrpVal: 1.779 ± 0.401
0.0TrpTrp: 0.0 ± 0.0
0.593TrpTyr: 0.593 ± 0.479
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.966TyrAla: 2.966 ± 0.69
2.372TyrCys: 2.372 ± 1.047
1.779TyrAsp: 1.779 ± 0.401
0.0TyrGlu: 0.0 ± 0.0
1.779TyrPhe: 1.779 ± 0.401
4.152TyrGly: 4.152 ± 0.816
0.0TyrHis: 0.0 ± 0.0
2.372TyrIle: 2.372 ± 0.803
0.0TyrLys: 0.0 ± 0.0
4.152TyrLeu: 4.152 ± 0.816
1.186TyrMet: 1.186 ± 0.149
1.779TyrAsn: 1.779 ± 0.401
2.966TyrPro: 2.966 ± 0.439
0.593TyrGln: 0.593 ± 0.416
2.966TyrArg: 2.966 ± 1.214
4.152TyrSer: 4.152 ± 1.15
2.372TyrThr: 2.372 ± 1.047
1.779TyrVal: 1.779 ± 0.401
1.186TyrTrp: 1.186 ± 0.958
1.779TyrTyr: 1.779 ± 1.391
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1687 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski