Amino acid dipepetide frequency for Desulfocapsa sulfexigens (strain DSM 10523 / SB164P1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.276AlaAla: 7.276 ± 0.111	1.026AlaCys: 1.026 ± 0.037	4.242AlaAsp: 4.242 ± 0.059	5.194AlaGlu: 5.194 ± 0.068	3.044AlaPhe: 3.044 ± 0.057	6.163AlaGly: 6.163 ± 0.095	1.457AlaHis: 1.457 ± 0.037	5.572AlaIle: 5.572 ± 0.084	3.968AlaLys: 3.968 ± 0.074	7.992AlaLeu: 7.992 ± 0.095	2.416AlaMet: 2.416 ± 0.051	2.548AlaAsn: 2.548 ± 0.052	2.564AlaPro: 2.564 ± 0.058	2.353AlaGln: 2.353 ± 0.043	3.779AlaArg: 3.779 ± 0.055	4.563AlaSer: 4.563 ± 0.067	4.25AlaThr: 4.25 ± 0.067	5.752AlaVal: 5.752 ± 0.08	0.71AlaTrp: 0.71 ± 0.029	1.873AlaTyr: 1.873 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.824CysAla: 0.824 ± 0.031	0.251CysCys: 0.251 ± 0.015	0.695CysAsp: 0.695 ± 0.03	0.7CysGlu: 0.7 ± 0.026	0.604CysPhe: 0.604 ± 0.024	1.189CysGly: 1.189 ± 0.039	0.542CysHis: 0.542 ± 0.039	0.745CysIle: 0.745 ± 0.026	0.619CysLys: 0.619 ± 0.023	1.329CysLeu: 1.329 ± 0.032	0.318CysMet: 0.318 ± 0.017	0.545CysAsn: 0.545 ± 0.023	0.729CysPro: 0.729 ± 0.03	0.416CysGln: 0.416 ± 0.019	0.755CysArg: 0.755 ± 0.027	1.013CysSer: 1.013 ± 0.031	0.685CysThr: 0.685 ± 0.028	0.744CysVal: 0.744 ± 0.029	0.155CysTrp: 0.155 ± 0.012	0.425CysTyr: 0.425 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.789AspAla: 3.789 ± 0.057	0.74AspCys: 0.74 ± 0.027	3.181AspAsp: 3.181 ± 0.201	3.595AspGlu: 3.595 ± 0.061	2.761AspPhe: 2.761 ± 0.051	3.792AspGly: 3.792 ± 0.071	1.16AspHis: 1.16 ± 0.031	4.351AspIle: 4.351 ± 0.067	2.871AspLys: 2.871 ± 0.049	5.778AspLeu: 5.778 ± 0.084	1.378AspMet: 1.378 ± 0.031	2.148AspAsn: 2.148 ± 0.054	2.542AspPro: 2.542 ± 0.047	1.777AspGln: 1.777 ± 0.038	2.733AspArg: 2.733 ± 0.048	3.505AspSer: 3.505 ± 0.062	3.002AspThr: 3.002 ± 0.059	3.437AspVal: 3.437 ± 0.054	0.653AspTrp: 0.653 ± 0.027	1.738AspTyr: 1.738 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	4.94GluAla: 4.94 ± 0.069	0.65GluCys: 0.65 ± 0.026	3.277GluAsp: 3.277 ± 0.058	5.111GluGlu: 5.111 ± 0.086	2.264GluPhe: 2.264 ± 0.046	3.724GluGly: 3.724 ± 0.061	1.314GluHis: 1.314 ± 0.034	4.966GluIle: 4.966 ± 0.062	5.35GluLys: 5.35 ± 0.081	6.558GluLeu: 6.558 ± 0.083	1.872GluMet: 1.872 ± 0.044	3.069GluAsn: 3.069 ± 0.06	1.865GluPro: 1.865 ± 0.041	3.038GluGln: 3.038 ± 0.055	3.366GluArg: 3.366 ± 0.054	3.746GluSer: 3.746 ± 0.064	3.45GluThr: 3.45 ± 0.059	4.089GluVal: 4.089 ± 0.059	0.595GluTrp: 0.595 ± 0.021	1.838GluTyr: 1.838 ± 0.042	0.0GluXaa: 0.0 ± 0.0
Phe	3.107PheAla: 3.107 ± 0.05	0.739PheCys: 0.739 ± 0.027	2.542PheAsp: 2.542 ± 0.045	2.229PheGlu: 2.229 ± 0.041	2.732PhePhe: 2.732 ± 0.058	3.073PheGly: 3.073 ± 0.054	0.983PheHis: 0.983 ± 0.029	2.816PheIle: 2.816 ± 0.044	1.954PheLys: 1.954 ± 0.042	5.025PheLeu: 5.025 ± 0.083	1.049PheMet: 1.049 ± 0.029	1.737PheAsn: 1.737 ± 0.042	1.899PhePro: 1.899 ± 0.04	1.543PheGln: 1.543 ± 0.036	2.042PheArg: 2.042 ± 0.039	3.801PheSer: 3.801 ± 0.065	2.645PheThr: 2.645 ± 0.043	2.881PheVal: 2.881 ± 0.056	0.508PheTrp: 0.508 ± 0.025	1.406PheTyr: 1.406 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	5.088GlyAla: 5.088 ± 0.082	1.151GlyCys: 1.151 ± 0.031	3.677GlyAsp: 3.677 ± 0.068	4.252GlyGlu: 4.252 ± 0.066	3.314GlyPhe: 3.314 ± 0.057	5.323GlyGly: 5.323 ± 0.089	1.58GlyHis: 1.58 ± 0.039	5.426GlyIle: 5.426 ± 0.075	4.788GlyLys: 4.788 ± 0.068	7.042GlyLeu: 7.042 ± 0.091	2.173GlyMet: 2.173 ± 0.044	2.79GlyAsn: 2.79 ± 0.064	1.98GlyPro: 1.98 ± 0.048	2.358GlyGln: 2.358 ± 0.04	3.674GlyArg: 3.674 ± 0.06	4.505GlySer: 4.505 ± 0.065	4.033GlyThr: 4.033 ± 0.071	5.038GlyVal: 5.038 ± 0.073	0.836GlyTrp: 0.836 ± 0.029	2.517GlyTyr: 2.517 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.412HisAla: 1.412 ± 0.036	0.385HisCys: 0.385 ± 0.018	1.264HisAsp: 1.264 ± 0.038	1.152HisGlu: 1.152 ± 0.032	1.122HisPhe: 1.122 ± 0.032	1.755HisGly: 1.755 ± 0.042	0.651HisHis: 0.651 ± 0.027	1.488HisIle: 1.488 ± 0.04	1.027HisLys: 1.027 ± 0.032	2.26HisLeu: 2.26 ± 0.044	0.431HisMet: 0.431 ± 0.018	0.873HisAsn: 0.873 ± 0.027	1.311HisPro: 1.311 ± 0.033	0.769HisGln: 0.769 ± 0.024	1.107HisArg: 1.107 ± 0.028	1.432HisSer: 1.432 ± 0.035	1.096HisThr: 1.096 ± 0.031	1.195HisVal: 1.195 ± 0.033	0.236HisTrp: 0.236 ± 0.015	0.758HisTyr: 0.758 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.607IleAla: 5.607 ± 0.08	0.952IleCys: 0.952 ± 0.029	4.01IleAsp: 4.01 ± 0.054	4.205IleGlu: 4.205 ± 0.061	3.072IlePhe: 3.072 ± 0.062	5.004IleGly: 5.004 ± 0.076	1.68IleHis: 1.68 ± 0.035	4.877IleIle: 4.877 ± 0.075	3.553IleLys: 3.553 ± 0.06	7.306IleLeu: 7.306 ± 0.09	1.586IleMet: 1.586 ± 0.036	2.81IleAsn: 2.81 ± 0.052	3.364IlePro: 3.364 ± 0.051	2.454IleGln: 2.454 ± 0.047	3.673IleArg: 3.673 ± 0.053	5.078IleSer: 5.078 ± 0.068	4.036IleThr: 4.036 ± 0.069	4.505IleVal: 4.505 ± 0.06	0.592IleTrp: 0.592 ± 0.022	1.816IleTyr: 1.816 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.097LysAla: 4.097 ± 0.068	0.535LysCys: 0.535 ± 0.025	3.085LysAsp: 3.085 ± 0.056	4.631LysGlu: 4.631 ± 0.071	1.631LysPhe: 1.631 ± 0.034	3.826LysGly: 3.826 ± 0.062	1.103LysHis: 1.103 ± 0.031	4.21LysIle: 4.21 ± 0.065	4.979LysLys: 4.979 ± 0.08	4.877LysLeu: 4.877 ± 0.075	1.669LysMet: 1.669 ± 0.041	2.953LysAsn: 2.953 ± 0.058	1.993LysPro: 1.993 ± 0.043	2.402LysGln: 2.402 ± 0.052	3.074LysArg: 3.074 ± 0.057	3.296LysSer: 3.296 ± 0.056	3.258LysThr: 3.258 ± 0.053	3.491LysVal: 3.491 ± 0.059	0.498LysTrp: 0.498 ± 0.021	1.583LysTyr: 1.583 ± 0.04	0.0LysXaa: 0.0 ± 0.0
Leu	9.053LeuAla: 9.053 ± 0.094	1.409LeuCys: 1.409 ± 0.035	5.566LeuAsp: 5.566 ± 0.078	6.418LeuGlu: 6.418 ± 0.089	5.113LeuPhe: 5.113 ± 0.084	6.933LeuGly: 6.933 ± 0.084	2.245LeuHis: 2.245 ± 0.05	6.503LeuIle: 6.503 ± 0.082	5.567LeuLys: 5.567 ± 0.073	12.015LeuLeu: 12.015 ± 0.14	2.293LeuMet: 2.293 ± 0.052	3.753LeuAsn: 3.753 ± 0.058	4.761LeuPro: 4.761 ± 0.059	4.347LeuGln: 4.347 ± 0.069	5.092LeuArg: 5.092 ± 0.077	7.592LeuSer: 7.592 ± 0.099	5.709LeuThr: 5.709 ± 0.071	6.676LeuVal: 6.676 ± 0.077	0.928LeuTrp: 0.928 ± 0.033	2.86LeuTyr: 2.86 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	2.614MetAla: 2.614 ± 0.049	0.218MetCys: 0.218 ± 0.013	1.502MetAsp: 1.502 ± 0.038	1.869MetGlu: 1.869 ± 0.042	0.849MetPhe: 0.849 ± 0.029	1.89MetGly: 1.89 ± 0.043	0.484MetHis: 0.484 ± 0.019	1.607MetIle: 1.607 ± 0.035	1.679MetLys: 1.679 ± 0.04	2.459MetLeu: 2.459 ± 0.05	0.636MetMet: 0.636 ± 0.024	1.139MetAsn: 1.139 ± 0.03	1.07MetPro: 1.07 ± 0.03	0.965MetGln: 0.965 ± 0.029	1.205MetArg: 1.205 ± 0.03	1.579MetSer: 1.579 ± 0.039	1.584MetThr: 1.584 ± 0.034	1.903MetVal: 1.903 ± 0.038	0.166MetTrp: 0.166 ± 0.012	0.534MetTyr: 0.534 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	2.535AsnAla: 2.535 ± 0.04	0.571AsnCys: 0.571 ± 0.022	2.106AsnAsp: 2.106 ± 0.055	2.155AsnGlu: 2.155 ± 0.042	1.639AsnPhe: 1.639 ± 0.041	2.77AsnGly: 2.77 ± 0.058	0.884AsnHis: 0.884 ± 0.029	3.148AsnIle: 3.148 ± 0.047	2.149AsnLys: 2.149 ± 0.044	3.972AsnLeu: 3.972 ± 0.062	1.051AsnMet: 1.051 ± 0.027	1.774AsnAsn: 1.774 ± 0.037	2.069AsnPro: 2.069 ± 0.05	1.337AsnGln: 1.337 ± 0.034	2.306AsnArg: 2.306 ± 0.043	2.756AsnSer: 2.756 ± 0.054	2.118AsnThr: 2.118 ± 0.042	2.396AsnVal: 2.396 ± 0.051	0.463AsnTrp: 0.463 ± 0.022	1.259AsnTyr: 1.259 ± 0.032	0.0AsnXaa: 0.0 ± 0.0
Pro	3.111ProAla: 3.111 ± 0.051	0.485ProCys: 0.485 ± 0.021	2.792ProAsp: 2.792 ± 0.046	3.619ProGlu: 3.619 ± 0.057	1.991ProPhe: 1.991 ± 0.046	3.239ProGly: 3.239 ± 0.047	0.893ProHis: 0.893 ± 0.03	2.356ProIle: 2.356 ± 0.05	1.799ProLys: 1.799 ± 0.043	4.4ProLeu: 4.4 ± 0.064	0.903ProMet: 0.903 ± 0.027	1.197ProAsn: 1.197 ± 0.032	1.691ProPro: 1.691 ± 0.038	1.367ProGln: 1.367 ± 0.033	1.53ProArg: 1.53 ± 0.04	2.348ProSer: 2.348 ± 0.046	1.917ProThr: 1.917 ± 0.038	3.405ProVal: 3.405 ± 0.06	0.486ProTrp: 0.486 ± 0.021	1.22ProTyr: 1.22 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.016GlnAla: 3.016 ± 0.055	0.397GlnCys: 0.397 ± 0.02	1.787GlnAsp: 1.787 ± 0.042	2.722GlnGlu: 2.722 ± 0.05	1.426GlnPhe: 1.426 ± 0.035	2.485GlnGly: 2.485 ± 0.046	0.739GlnHis: 0.739 ± 0.023	2.548GlnIle: 2.548 ± 0.046	2.569GlnLys: 2.569 ± 0.042	3.802GlnLeu: 3.802 ± 0.059	0.943GlnMet: 0.943 ± 0.027	1.491GlnAsn: 1.491 ± 0.034	1.323GlnPro: 1.323 ± 0.037	1.856GlnGln: 1.856 ± 0.047	1.831GlnArg: 1.831 ± 0.046	2.171GlnSer: 2.171 ± 0.042	1.85GlnThr: 1.85 ± 0.042	2.376GlnVal: 2.376 ± 0.046	0.406GlnTrp: 0.406 ± 0.016	1.11GlnTyr: 1.11 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	3.216ArgAla: 3.216 ± 0.053	0.618ArgCys: 0.618 ± 0.025	2.741ArgAsp: 2.741 ± 0.046	3.739ArgGlu: 3.739 ± 0.063	2.37ArgPhe: 2.37 ± 0.044	2.927ArgGly: 2.927 ± 0.051	1.119ArgHis: 1.119 ± 0.036	3.846ArgIle: 3.846 ± 0.063	3.405ArgLys: 3.405 ± 0.064	5.216ArgLeu: 5.216 ± 0.074	1.438ArgMet: 1.438 ± 0.036	2.115ArgAsn: 2.115 ± 0.037	1.753ArgPro: 1.753 ± 0.04	2.049ArgGln: 2.049 ± 0.043	2.634ArgArg: 2.634 ± 0.054	3.027ArgSer: 3.027 ± 0.045	2.343ArgThr: 2.343 ± 0.04	3.207ArgVal: 3.207 ± 0.053	0.551ArgTrp: 0.551 ± 0.021	1.749ArgTyr: 1.749 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	4.324SerAla: 4.324 ± 0.066	0.996SerCys: 0.996 ± 0.033	3.429SerAsp: 3.429 ± 0.059	3.626SerGlu: 3.626 ± 0.067	3.369SerPhe: 3.369 ± 0.057	5.59SerGly: 5.59 ± 0.075	1.441SerHis: 1.441 ± 0.041	4.497SerIle: 4.497 ± 0.062	3.038SerLys: 3.038 ± 0.053	7.295SerLeu: 7.295 ± 0.099	1.767SerMet: 1.767 ± 0.039	2.352SerAsn: 2.352 ± 0.043	2.856SerPro: 2.856 ± 0.059	2.259SerGln: 2.259 ± 0.043	3.416SerArg: 3.416 ± 0.056	4.724SerSer: 4.724 ± 0.08	3.444SerThr: 3.444 ± 0.058	4.414SerVal: 4.414 ± 0.055	0.793SerTrp: 0.793 ± 0.027	2.077SerTyr: 2.077 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.496ThrAla: 4.496 ± 0.068	0.66ThrCys: 0.66 ± 0.02	2.932ThrAsp: 2.932 ± 0.05	3.254ThrGlu: 3.254 ± 0.056	2.365ThrPhe: 2.365 ± 0.045	4.607ThrGly: 4.607 ± 0.066	1.071ThrHis: 1.071 ± 0.029	4.243ThrIle: 4.243 ± 0.068	2.375ThrLys: 2.375 ± 0.042	5.993ThrLeu: 5.993 ± 0.075	1.403ThrMet: 1.403 ± 0.034	1.914ThrAsn: 1.914 ± 0.037	2.654ThrPro: 2.654 ± 0.054	1.531ThrGln: 1.531 ± 0.036	2.443ThrArg: 2.443 ± 0.047	3.276ThrSer: 3.276 ± 0.052	3.232ThrThr: 3.232 ± 0.07	4.231ThrVal: 4.231 ± 0.064	0.516ThrTrp: 0.516 ± 0.023	1.418ThrTyr: 1.418 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	5.754ValAla: 5.754 ± 0.081	0.888ValCys: 0.888 ± 0.026	3.873ValAsp: 3.873 ± 0.059	4.336ValGlu: 4.336 ± 0.066	3.011ValPhe: 3.011 ± 0.054	4.331ValGly: 4.331 ± 0.072	1.422ValHis: 1.422 ± 0.037	4.651ValIle: 4.651 ± 0.059	3.448ValLys: 3.448 ± 0.054	7.041ValLeu: 7.041 ± 0.093	1.678ValMet: 1.678 ± 0.042	2.556ValAsn: 2.556 ± 0.048	2.585ValPro: 2.585 ± 0.049	2.196ValGln: 2.196 ± 0.046	3.19ValArg: 3.19 ± 0.062	4.618ValSer: 4.618 ± 0.068	3.995ValThr: 3.995 ± 0.059	4.981ValVal: 4.981 ± 0.081	0.597ValTrp: 0.597 ± 0.022	1.744ValTyr: 1.744 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.698TrpAla: 0.698 ± 0.025	0.138TrpCys: 0.138 ± 0.011	0.565TrpAsp: 0.565 ± 0.022	0.601TrpGlu: 0.601 ± 0.024	0.494TrpPhe: 0.494 ± 0.022	0.659TrpGly: 0.659 ± 0.023	0.241TrpHis: 0.241 ± 0.014	0.658TrpIle: 0.658 ± 0.024	0.633TrpLys: 0.633 ± 0.026	1.212TrpLeu: 1.212 ± 0.04	0.287TrpMet: 0.287 ± 0.017	0.464TrpAsn: 0.464 ± 0.019	0.4TrpPro: 0.4 ± 0.018	0.574TrpGln: 0.574 ± 0.024	0.486TrpArg: 0.486 ± 0.019	0.58TrpSer: 0.58 ± 0.022	0.434TrpThr: 0.434 ± 0.019	0.592TrpVal: 0.592 ± 0.023	0.139TrpTrp: 0.139 ± 0.012	0.323TrpTyr: 0.323 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.785TyrAla: 1.785 ± 0.041	0.475TyrCys: 0.475 ± 0.019	1.668TyrAsp: 1.668 ± 0.035	1.672TyrGlu: 1.672 ± 0.039	1.538TyrPhe: 1.538 ± 0.037	2.266TyrGly: 2.266 ± 0.052	0.711TyrHis: 0.711 ± 0.026	1.673TyrIle: 1.673 ± 0.042	1.42TyrLys: 1.42 ± 0.035	3.263TyrLeu: 3.263 ± 0.059	0.659TyrMet: 0.659 ± 0.024	1.231TyrAsn: 1.231 ± 0.038	1.344TyrPro: 1.344 ± 0.029	1.26TyrGln: 1.26 ± 0.035	1.728TyrArg: 1.728 ± 0.039	2.096TyrSer: 2.096 ± 0.045	1.533TyrThr: 1.533 ± 0.037	1.579TyrVal: 1.579 ± 0.039	0.348TyrTrp: 0.348 ± 0.017	1.067TyrTyr: 1.067 ± 0.037	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3514 proteins (1190136 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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