Amino acid dipepetide frequency for Barley yellow dwarf virus (isolate PAV) (BYDV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.159AlaAla: 5.159 ± 1.447
1.29AlaCys: 1.29 ± 0.454
1.72AlaAsp: 1.72 ± 0.872
6.879AlaGlu: 6.879 ± 1.792
1.72AlaPhe: 1.72 ± 0.444
3.869AlaGly: 3.869 ± 1.358
0.86AlaHis: 0.86 ± 0.436
4.299AlaIle: 4.299 ± 1.401
5.589AlaLys: 5.589 ± 1.336
4.729AlaLeu: 4.729 ± 1.137
0.43AlaMet: 0.43 ± 0.313
6.449AlaAsn: 6.449 ± 2.705
5.589AlaPro: 5.589 ± 1.379
4.729AlaGln: 4.729 ± 1.668
6.879AlaArg: 6.879 ± 2.498
8.169AlaSer: 8.169 ± 1.298
3.439AlaThr: 3.439 ± 0.851
3.869AlaVal: 3.869 ± 1.687
0.86AlaTrp: 0.86 ± 0.436
1.29AlaTyr: 1.29 ± 0.626
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.86CysCys: 0.86 ± 1.694
0.86CysAsp: 0.86 ± 0.745
1.72CysGlu: 1.72 ± 0.591
0.86CysPhe: 0.86 ± 0.436
0.86CysGly: 0.86 ± 0.626
0.0CysHis: 0.0 ± 0.0
0.43CysIle: 0.43 ± 0.847
1.29CysLys: 1.29 ± 0.454
0.43CysLeu: 0.43 ± 0.313
0.0CysMet: 0.0 ± 0.0
0.43CysAsn: 0.43 ± 0.313
1.72CysPro: 1.72 ± 0.554
0.86CysGln: 0.86 ± 0.326
0.43CysArg: 0.43 ± 0.847
0.86CysSer: 0.86 ± 0.866
0.43CysThr: 0.43 ± 0.313
0.43CysVal: 0.43 ± 0.313
0.86CysTrp: 0.86 ± 0.436
0.86CysTyr: 0.86 ± 0.436
0.0CysXaa: 0.0 ± 0.0
Asp
4.299AspAla: 4.299 ± 0.661
0.86AspCys: 0.86 ± 0.326
1.72AspAsp: 1.72 ± 1.053
4.299AspGlu: 4.299 ± 0.976
2.58AspPhe: 2.58 ± 1.308
3.009AspGly: 3.009 ± 0.884
0.86AspHis: 0.86 ± 0.326
4.299AspIle: 4.299 ± 1.623
2.15AspLys: 2.15 ± 0.678
3.009AspLeu: 3.009 ± 1.284
0.0AspMet: 0.0 ± 0.0
2.58AspAsn: 2.58 ± 0.463
0.86AspPro: 0.86 ± 0.637
1.72AspGln: 1.72 ± 0.652
0.86AspArg: 0.86 ± 0.326
4.299AspSer: 4.299 ± 0.94
3.869AspThr: 3.869 ± 1.073
4.729AspVal: 4.729 ± 1.195
0.0AspTrp: 0.0 ± 0.0
0.43AspTyr: 0.43 ± 0.313
0.0AspXaa: 0.0 ± 0.0
Glu
8.598GluAla: 8.598 ± 1.942
0.0GluCys: 0.0 ± 0.0
4.299GluAsp: 4.299 ± 1.004
7.309GluGlu: 7.309 ± 2.59
3.869GluPhe: 3.869 ± 0.843
2.58GluGly: 2.58 ± 1.594
1.29GluHis: 1.29 ± 0.94
2.58GluIle: 2.58 ± 0.817
5.589GluLys: 5.589 ± 2.239
4.729GluLeu: 4.729 ± 1.203
1.72GluMet: 1.72 ± 0.758
2.15GluAsn: 2.15 ± 0.534
4.299GluPro: 4.299 ± 1.452
4.299GluGln: 4.299 ± 1.15
5.589GluArg: 5.589 ± 1.326
3.009GluSer: 3.009 ± 0.884
3.439GluThr: 3.439 ± 0.779
6.879GluVal: 6.879 ± 2.215
0.0GluTrp: 0.0 ± 0.0
2.15GluTyr: 2.15 ± 0.975
0.0GluXaa: 0.0 ± 0.0
Phe
2.15PheAla: 2.15 ± 1.028
0.43PheCys: 0.43 ± 0.313
0.86PheAsp: 0.86 ± 0.626
3.439PheGlu: 3.439 ± 1.233
2.15PhePhe: 2.15 ± 0.709
3.869PheGly: 3.869 ± 0.504
0.43PheHis: 0.43 ± 0.373
3.869PheIle: 3.869 ± 0.837
4.729PheLys: 4.729 ± 1.103
2.15PheLeu: 2.15 ± 0.809
0.0PheMet: 0.0 ± 0.402
0.86PheAsn: 0.86 ± 0.626
0.86PhePro: 0.86 ± 0.815
2.58PheGln: 2.58 ± 0.958
1.72PheArg: 1.72 ± 1.098
0.86PheSer: 0.86 ± 0.549
3.869PheThr: 3.869 ± 0.748
3.439PheVal: 3.439 ± 0.914
1.29PheTrp: 1.29 ± 0.802
0.86PheTyr: 0.86 ± 0.326
0.0PheXaa: 0.0 ± 0.0
Gly
6.019GlyAla: 6.019 ± 2.043
0.43GlyCys: 0.43 ± 0.373
3.009GlyAsp: 3.009 ± 1.254
0.86GlyGlu: 0.86 ± 0.436
3.009GlyPhe: 3.009 ± 1.014
4.299GlyGly: 4.299 ± 1.59
1.72GlyHis: 1.72 ± 0.444
2.58GlyIle: 2.58 ± 0.81
3.009GlyLys: 3.009 ± 0.957
5.159GlyLeu: 5.159 ± 1.659
0.86GlyMet: 0.86 ± 0.626
2.15GlyAsn: 2.15 ± 1.341
2.58GlyPro: 2.58 ± 1.647
4.729GlyGln: 4.729 ± 2.573
5.159GlyArg: 5.159 ± 1.387
1.72GlySer: 1.72 ± 0.646
5.159GlyThr: 5.159 ± 2.357
4.299GlyVal: 4.299 ± 1.428
0.0GlyTrp: 0.0 ± 0.0
2.15GlyTyr: 2.15 ± 0.809
0.0GlyXaa: 0.0 ± 0.0
His
2.15HisAla: 2.15 ± 0.622
0.86HisCys: 0.86 ± 0.436
1.29HisAsp: 1.29 ± 0.622
0.0HisGlu: 0.0 ± 0.0
0.43HisPhe: 0.43 ± 0.313
0.43HisGly: 0.43 ± 0.313
0.0HisHis: 0.0 ± 0.0
0.86HisIle: 0.86 ± 0.745
0.86HisLys: 0.86 ± 0.326
1.72HisLeu: 1.72 ± 0.883
0.86HisMet: 0.86 ± 0.436
0.43HisAsn: 0.43 ± 0.313
0.43HisPro: 0.43 ± 0.823
1.72HisGln: 1.72 ± 0.883
1.29HisArg: 1.29 ± 0.454
0.86HisSer: 0.86 ± 0.626
0.43HisThr: 0.43 ± 0.672
1.72HisVal: 1.72 ± 1.208
0.43HisTrp: 0.43 ± 0.313
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.729IleAla: 4.729 ± 1.196
0.43IleCys: 0.43 ± 0.313
1.72IleAsp: 1.72 ± 0.646
3.439IleGlu: 3.439 ± 0.955
1.72IlePhe: 1.72 ± 0.554
3.869IleGly: 3.869 ± 0.908
0.0IleHis: 0.0 ± 0.0
3.009IleIle: 3.009 ± 0.957
4.729IleLys: 4.729 ± 1.317
4.729IleLeu: 4.729 ± 0.905
1.72IleMet: 1.72 ± 0.883
3.439IleAsn: 3.439 ± 0.79
3.009IlePro: 3.009 ± 0.918
0.43IleGln: 0.43 ± 0.313
3.009IleArg: 3.009 ± 1.263
4.729IleSer: 4.729 ± 1.226
4.729IleThr: 4.729 ± 1.007
1.72IleVal: 1.72 ± 0.701
0.0IleTrp: 0.0 ± 0.0
2.15IleTyr: 2.15 ± 0.678
0.0IleXaa: 0.0 ± 0.0
Lys
5.589LysAla: 5.589 ± 0.947
0.86LysCys: 0.86 ± 0.326
7.739LysAsp: 7.739 ± 2.456
4.729LysGlu: 4.729 ± 0.919
2.58LysPhe: 2.58 ± 0.633
2.58LysGly: 2.58 ± 0.463
1.72LysHis: 1.72 ± 0.444
2.58LysIle: 2.58 ± 0.633
4.299LysLys: 4.299 ± 1.813
7.739LysLeu: 7.739 ± 2.086
2.15LysMet: 2.15 ± 0.892
3.009LysAsn: 3.009 ± 0.907
2.58LysPro: 2.58 ± 0.841
2.15LysGln: 2.15 ± 0.449
2.58LysArg: 2.58 ± 0.645
7.309LysSer: 7.309 ± 1.71
5.159LysThr: 5.159 ± 1.28
3.009LysVal: 3.009 ± 1.254
0.86LysTrp: 0.86 ± 0.626
2.15LysTyr: 2.15 ± 0.534
0.0LysXaa: 0.0 ± 0.0
Leu
3.439LeuAla: 3.439 ± 1.016
1.29LeuCys: 1.29 ± 0.519
3.439LeuAsp: 3.439 ± 1.216
6.449LeuGlu: 6.449 ± 2.369
0.43LeuPhe: 0.43 ± 0.313
3.439LeuGly: 3.439 ± 1.007
0.86LeuHis: 0.86 ± 0.815
2.58LeuIle: 2.58 ± 0.631
9.888LeuLys: 9.888 ± 2.147
5.589LeuLeu: 5.589 ± 1.27
3.439LeuMet: 3.439 ± 0.665
1.72LeuAsn: 1.72 ± 0.883
1.72LeuPro: 1.72 ± 0.823
2.58LeuGln: 2.58 ± 1.468
3.869LeuArg: 3.869 ± 0.71
9.028LeuSer: 9.028 ± 3.33
2.15LeuThr: 2.15 ± 1.548
4.729LeuVal: 4.729 ± 0.894
0.43LeuTrp: 0.43 ± 0.672
3.009LeuTyr: 3.009 ± 0.459
0.0LeuXaa: 0.0 ± 0.0
Met
2.58MetAla: 2.58 ± 0.515
1.29MetCys: 1.29 ± 0.622
1.72MetAsp: 1.72 ± 0.444
2.58MetGlu: 2.58 ± 0.899
2.15MetPhe: 2.15 ± 1.028
0.86MetGly: 0.86 ± 0.637
0.86MetHis: 0.86 ± 0.626
0.0MetIle: 0.0 ± 0.0
1.29MetLys: 1.29 ± 0.362
1.72MetLeu: 1.72 ± 0.554
0.43MetMet: 0.43 ± 0.313
0.86MetAsn: 0.86 ± 0.549
0.0MetPro: 0.0 ± 0.0
0.86MetGln: 0.86 ± 0.832
0.0MetArg: 0.0 ± 0.0
3.439MetSer: 3.439 ± 0.74
1.72MetThr: 1.72 ± 0.646
2.15MetVal: 2.15 ± 0.907
0.0MetTrp: 0.0 ± 0.0
1.29MetTyr: 1.29 ± 0.886
0.0MetXaa: 0.0 ± 0.0
Asn
4.729AsnAla: 4.729 ± 1.48
0.86AsnCys: 0.86 ± 0.436
0.86AsnAsp: 0.86 ± 0.436
2.58AsnGlu: 2.58 ± 1.039
2.15AsnPhe: 2.15 ± 0.952
5.589AsnGly: 5.589 ± 1.642
0.86AsnHis: 0.86 ± 0.626
3.009AsnIle: 3.009 ± 0.951
1.72AsnLys: 1.72 ± 0.444
0.86AsnLeu: 0.86 ± 0.549
1.72AsnMet: 1.72 ± 0.444
1.72AsnAsn: 1.72 ± 0.652
0.86AsnPro: 0.86 ± 1.231
2.58AsnGln: 2.58 ± 1.246
1.29AsnArg: 1.29 ± 0.802
4.729AsnSer: 4.729 ± 2.078
2.15AsnThr: 2.15 ± 0.952
2.58AsnVal: 2.58 ± 0.793
0.43AsnTrp: 0.43 ± 0.373
0.86AsnTyr: 0.86 ± 0.745
0.0AsnXaa: 0.0 ± 0.0
Pro
3.009ProAla: 3.009 ± 1.355
0.0ProCys: 0.0 ± 0.0
1.29ProAsp: 1.29 ± 0.556
5.159ProGlu: 5.159 ± 2.011
0.86ProPhe: 0.86 ± 0.815
0.86ProGly: 0.86 ± 0.698
0.86ProHis: 0.86 ± 0.796
4.299ProIle: 4.299 ± 1.357
3.009ProLys: 3.009 ± 2.077
1.72ProLeu: 1.72 ± 0.766
0.86ProMet: 0.86 ± 0.745
1.29ProAsn: 1.29 ± 0.454
3.009ProPro: 3.009 ± 2.861
0.86ProGln: 0.86 ± 0.745
3.869ProArg: 3.869 ± 1.231
3.869ProSer: 3.869 ± 2.553
8.169ProThr: 8.169 ± 2.811
4.729ProVal: 4.729 ± 0.688
0.43ProTrp: 0.43 ± 0.672
0.43ProTyr: 0.43 ± 0.313
0.0ProXaa: 0.0 ± 0.0
Gln
2.58GlnAla: 2.58 ± 1.513
1.29GlnCys: 1.29 ± 0.454
1.29GlnAsp: 1.29 ± 0.724
2.58GlnGlu: 2.58 ± 0.695
4.729GlnPhe: 4.729 ± 1.094
2.15GlnGly: 2.15 ± 0.753
1.72GlnHis: 1.72 ± 0.908
1.72GlnIle: 1.72 ± 0.572
2.58GlnLys: 2.58 ± 0.958
3.009GlnLeu: 3.009 ± 1.084
0.86GlnMet: 0.86 ± 0.704
1.72GlnAsn: 1.72 ± 0.646
2.15GlnPro: 2.15 ± 1.191
0.86GlnGln: 0.86 ± 0.637
1.29GlnArg: 1.29 ± 2.017
4.729GlnSer: 4.729 ± 0.604
1.72GlnThr: 1.72 ± 0.701
1.72GlnVal: 1.72 ± 1.222
0.43GlnTrp: 0.43 ± 0.672
0.86GlnTyr: 0.86 ± 0.326
0.0GlnXaa: 0.0 ± 0.0
Arg
5.589ArgAla: 5.589 ± 0.998
0.0ArgCys: 0.0 ± 0.0
1.29ArgAsp: 1.29 ± 0.362
4.299ArgGlu: 4.299 ± 1.237
1.72ArgPhe: 1.72 ± 0.572
3.869ArgGly: 3.869 ± 0.837
0.43ArgHis: 0.43 ± 0.373
1.29ArgIle: 1.29 ± 0.626
1.29ArgLys: 1.29 ± 0.454
5.589ArgLeu: 5.589 ± 2.239
3.009ArgMet: 3.009 ± 0.812
3.009ArgAsn: 3.009 ± 2.421
4.299ArgPro: 4.299 ± 1.862
2.58ArgGln: 2.58 ± 1.226
11.178ArgArg: 11.178 ± 4.935
6.449ArgSer: 6.449 ± 1.163
1.72ArgThr: 1.72 ± 0.646
2.15ArgVal: 2.15 ± 1.624
1.29ArgTrp: 1.29 ± 0.869
3.869ArgTyr: 3.869 ± 0.504
0.0ArgXaa: 0.0 ± 0.0
Ser
5.589SerAla: 5.589 ± 1.31
1.72SerCys: 1.72 ± 0.768
2.15SerAsp: 2.15 ± 0.952
3.869SerGlu: 3.869 ± 0.504
5.159SerPhe: 5.159 ± 1.131
7.309SerGly: 7.309 ± 0.782
2.15SerHis: 2.15 ± 0.666
5.159SerIle: 5.159 ± 1.496
6.019SerLys: 6.019 ± 1.422
5.589SerLeu: 5.589 ± 1.451
2.15SerMet: 2.15 ± 0.678
3.009SerAsn: 3.009 ± 2.189
3.009SerPro: 3.009 ± 1.114
2.58SerGln: 2.58 ± 1.166
4.729SerArg: 4.729 ± 1.37
5.159SerSer: 5.159 ± 2.098
5.159SerThr: 5.159 ± 1.98
8.169SerVal: 8.169 ± 2.337
0.0SerTrp: 0.0 ± 0.0
4.729SerTyr: 4.729 ± 1.019
0.0SerXaa: 0.0 ± 0.0
Thr
6.879ThrAla: 6.879 ± 2.966
0.43ThrCys: 0.43 ± 0.373
5.159ThrAsp: 5.159 ± 1.241
4.729ThrGlu: 4.729 ± 0.841
0.86ThrPhe: 0.86 ± 0.549
2.58ThrGly: 2.58 ± 0.874
0.43ThrHis: 0.43 ± 0.313
5.159ThrIle: 5.159 ± 2.074
1.72ThrLys: 1.72 ± 0.444
3.439ThrLeu: 3.439 ± 1.455
1.72ThrMet: 1.72 ± 0.646
3.009ThrAsn: 3.009 ± 0.807
6.879ThrPro: 6.879 ± 3.614
0.0ThrGln: 0.0 ± 0.0
5.589ThrArg: 5.589 ± 2.233
2.15ThrSer: 2.15 ± 0.952
3.869ThrThr: 3.869 ± 1.203
4.299ThrVal: 4.299 ± 0.955
1.29ThrTrp: 1.29 ± 0.362
2.15ThrTyr: 2.15 ± 0.678
0.0ThrXaa: 0.0 ± 0.0
Val
3.439ValAla: 3.439 ± 1.419
0.43ValCys: 0.43 ± 0.847
4.299ValAsp: 4.299 ± 0.792
7.309ValGlu: 7.309 ± 0.829
3.439ValPhe: 3.439 ± 1.395
5.159ValGly: 5.159 ± 1.755
0.0ValHis: 0.0 ± 0.0
1.72ValIle: 1.72 ± 0.761
7.739ValLys: 7.739 ± 3.028
4.299ValLeu: 4.299 ± 1.42
1.29ValMet: 1.29 ± 1.51
1.72ValAsn: 1.72 ± 0.591
3.009ValPro: 3.009 ± 0.807
3.009ValGln: 3.009 ± 1.259
3.869ValArg: 3.869 ± 1.016
6.019ValSer: 6.019 ± 1.76
3.009ValThr: 3.009 ± 0.843
4.299ValVal: 4.299 ± 1.742
0.0ValTrp: 0.0 ± 0.0
2.58ValTyr: 2.58 ± 0.631
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.43TrpCys: 0.43 ± 0.847
0.0TrpAsp: 0.0 ± 0.0
0.86TrpGlu: 0.86 ± 0.626
0.0TrpPhe: 0.0 ± 0.0
0.43TrpGly: 0.43 ± 0.373
0.0TrpHis: 0.0 ± 0.0
1.29TrpIle: 1.29 ± 0.362
0.0TrpLys: 0.0 ± 0.0
1.29TrpLeu: 1.29 ± 0.724
1.29TrpMet: 1.29 ± 0.454
0.86TrpAsn: 0.86 ± 0.436
0.0TrpPro: 0.0 ± 0.0
0.43TrpGln: 0.43 ± 0.313
0.43TrpArg: 0.43 ± 0.373
0.86TrpSer: 0.86 ± 0.698
0.86TrpThr: 0.86 ± 0.436
0.43TrpVal: 0.43 ± 0.672
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.29TyrAla: 1.29 ± 0.362
0.43TyrCys: 0.43 ± 0.313
1.72TyrAsp: 1.72 ± 0.793
1.29TyrGlu: 1.29 ± 0.626
0.43TyrPhe: 0.43 ± 0.313
1.29TyrGly: 1.29 ± 0.519
1.72TyrHis: 1.72 ± 0.554
2.58TyrIle: 2.58 ± 0.874
3.869TyrLys: 3.869 ± 1.229
2.58TyrLeu: 2.58 ± 0.631
0.86TyrMet: 0.86 ± 0.602
1.72TyrAsn: 1.72 ± 0.793
1.72TyrPro: 1.72 ± 0.652
0.43TyrGln: 0.43 ± 0.373
1.29TyrArg: 1.29 ± 0.745
5.159TyrSer: 5.159 ± 1.775
1.29TyrThr: 1.29 ± 0.992
1.29TyrVal: 1.29 ± 0.362
0.86TyrTrp: 0.86 ± 0.326
1.29TyrTyr: 1.29 ± 0.622
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2327 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski