Amino acid dipepetide frequency for Sistotremastrum niveocremeum HHB9708

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.266AlaAla: 7.266 ± 0.056	0.994AlaCys: 0.994 ± 0.013	3.874AlaAsp: 3.874 ± 0.03	4.635AlaGlu: 4.635 ± 0.034	3.253AlaPhe: 3.253 ± 0.024	4.762AlaGly: 4.762 ± 0.033	1.908AlaHis: 1.908 ± 0.019	4.237AlaIle: 4.237 ± 0.03	3.678AlaLys: 3.678 ± 0.031	8.291AlaLeu: 8.291 ± 0.042	1.711AlaMet: 1.711 ± 0.017	2.716AlaAsn: 2.716 ± 0.026	4.718AlaPro: 4.718 ± 0.042	3.143AlaGln: 3.143 ± 0.025	4.741AlaArg: 4.741 ± 0.034	7.472AlaSer: 7.472 ± 0.045	4.832AlaThr: 4.832 ± 0.028	4.982AlaVal: 4.982 ± 0.028	1.113AlaTrp: 1.113 ± 0.015	2.034AlaTyr: 2.034 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.92CysAla: 0.92 ± 0.013	0.213CysCys: 0.213 ± 0.006	0.659CysAsp: 0.659 ± 0.013	0.606CysGlu: 0.606 ± 0.012	0.521CysPhe: 0.521 ± 0.009	0.858CysGly: 0.858 ± 0.013	0.354CysHis: 0.354 ± 0.008	0.705CysIle: 0.705 ± 0.011	0.473CysLys: 0.473 ± 0.009	1.363CysLeu: 1.363 ± 0.018	0.242CysMet: 0.242 ± 0.007	0.416CysAsn: 0.416 ± 0.01	0.786CysPro: 0.786 ± 0.014	0.479CysGln: 0.479 ± 0.01	0.806CysArg: 0.806 ± 0.014	1.018CysSer: 1.018 ± 0.016	0.741CysThr: 0.741 ± 0.012	0.803CysVal: 0.803 ± 0.012	0.212CysTrp: 0.212 ± 0.006	0.32CysTyr: 0.32 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	4.504AspAla: 4.504 ± 0.032	0.621AspCys: 0.621 ± 0.012	4.04AspAsp: 4.04 ± 0.04	4.334AspGlu: 4.334 ± 0.03	2.137AspPhe: 2.137 ± 0.022	3.703AspGly: 3.703 ± 0.03	1.393AspHis: 1.393 ± 0.017	3.18AspIle: 3.18 ± 0.026	2.042AspLys: 2.042 ± 0.021	5.335AspLeu: 5.335 ± 0.034	1.094AspMet: 1.094 ± 0.014	1.673AspAsn: 1.673 ± 0.018	3.613AspPro: 3.613 ± 0.031	1.798AspGln: 1.798 ± 0.019	3.02AspArg: 3.02 ± 0.031	4.202AspSer: 4.202 ± 0.031	2.844AspThr: 2.844 ± 0.021	3.839AspVal: 3.839 ± 0.03	0.895AspTrp: 0.895 ± 0.013	1.4AspTyr: 1.4 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	4.796GluAla: 4.796 ± 0.037	0.69GluCys: 0.69 ± 0.012	4.01GluAsp: 4.01 ± 0.031	5.066GluGlu: 5.066 ± 0.044	1.99GluPhe: 1.99 ± 0.019	3.541GluGly: 3.541 ± 0.03	1.432GluHis: 1.432 ± 0.018	3.269GluIle: 3.269 ± 0.026	3.194GluLys: 3.194 ± 0.03	5.337GluLeu: 5.337 ± 0.032	1.313GluMet: 1.313 ± 0.015	2.109GluAsn: 2.109 ± 0.022	2.822GluPro: 2.822 ± 0.026	2.12GluGln: 2.12 ± 0.023	4.003GluArg: 4.003 ± 0.031	4.446GluSer: 4.446 ± 0.033	3.314GluThr: 3.314 ± 0.027	3.478GluVal: 3.478 ± 0.026	0.937GluTrp: 0.937 ± 0.014	1.501GluTyr: 1.501 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.014PheAla: 3.014 ± 0.024	0.556PheCys: 0.556 ± 0.01	2.394PheAsp: 2.394 ± 0.02	2.23PheGlu: 2.23 ± 0.021	1.675PhePhe: 1.675 ± 0.019	2.7PheGly: 2.7 ± 0.028	1.016PheHis: 1.016 ± 0.013	2.041PheIle: 2.041 ± 0.021	1.528PheLys: 1.528 ± 0.018	3.863PheLeu: 3.863 ± 0.035	0.732PheMet: 0.732 ± 0.012	1.397PheAsn: 1.397 ± 0.018	2.236PhePro: 2.236 ± 0.024	1.412PheGln: 1.412 ± 0.017	2.08PheArg: 2.08 ± 0.02	3.372PheSer: 3.372 ± 0.028	2.201PheThr: 2.201 ± 0.022	2.593PheVal: 2.593 ± 0.021	0.637PheTrp: 0.637 ± 0.01	1.059PheTyr: 1.059 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	4.493GlyAla: 4.493 ± 0.031	0.791GlyCys: 0.791 ± 0.012	3.268GlyAsp: 3.268 ± 0.03	3.262GlyGlu: 3.262 ± 0.024	2.524GlyPhe: 2.524 ± 0.023	4.886GlyGly: 4.886 ± 0.052	1.615GlyHis: 1.615 ± 0.016	3.322GlyIle: 3.322 ± 0.026	3.093GlyLys: 3.093 ± 0.029	5.543GlyLeu: 5.543 ± 0.035	1.332GlyMet: 1.332 ± 0.017	2.149GlyAsn: 2.149 ± 0.022	3.367GlyPro: 3.367 ± 0.031	2.125GlyGln: 2.125 ± 0.02	3.738GlyArg: 3.738 ± 0.033	5.475GlySer: 5.475 ± 0.037	3.775GlyThr: 3.775 ± 0.031	3.978GlyVal: 3.978 ± 0.03	1.094GlyTrp: 1.094 ± 0.015	1.785GlyTyr: 1.785 ± 0.022	0.0GlyXaa: 0.0 ± 0.0
His	1.973HisAla: 1.973 ± 0.02	0.378HisCys: 0.378 ± 0.009	1.388HisAsp: 1.388 ± 0.017	1.39HisGlu: 1.39 ± 0.016	1.063HisPhe: 1.063 ± 0.014	1.628HisGly: 1.628 ± 0.02	0.903HisHis: 0.903 ± 0.017	1.418HisIle: 1.418 ± 0.016	0.881HisLys: 0.881 ± 0.012	2.711HisLeu: 2.711 ± 0.023	0.454HisMet: 0.454 ± 0.009	0.864HisAsn: 0.864 ± 0.013	2.02HisPro: 2.02 ± 0.023	0.936HisGln: 0.936 ± 0.014	1.612HisArg: 1.612 ± 0.021	2.315HisSer: 2.315 ± 0.027	1.423HisThr: 1.423 ± 0.019	1.613HisVal: 1.613 ± 0.016	0.373HisTrp: 0.373 ± 0.008	0.707HisTyr: 0.707 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.349IleAla: 4.349 ± 0.035	0.779IleCys: 0.779 ± 0.012	2.981IleAsp: 2.981 ± 0.026	2.803IleGlu: 2.803 ± 0.023	2.182IlePhe: 2.182 ± 0.023	3.143IleGly: 3.143 ± 0.028	1.4IleHis: 1.4 ± 0.016	2.752IleIle: 2.752 ± 0.025	2.209IleLys: 2.209 ± 0.02	5.302IleLeu: 5.302 ± 0.036	0.992IleMet: 0.992 ± 0.014	1.778IleAsn: 1.778 ± 0.016	3.602IlePro: 3.602 ± 0.03	1.993IleGln: 1.993 ± 0.02	3.133IleArg: 3.133 ± 0.025	4.523IleSer: 4.523 ± 0.032	2.986IleThr: 2.986 ± 0.025	3.452IleVal: 3.452 ± 0.026	0.809IleTrp: 0.809 ± 0.014	1.405IleTyr: 1.405 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	3.978LysAla: 3.978 ± 0.033	0.488LysCys: 0.488 ± 0.009	2.475LysAsp: 2.475 ± 0.027	3.144LysGlu: 3.144 ± 0.028	1.534LysPhe: 1.534 ± 0.016	2.705LysGly: 2.705 ± 0.026	1.069LysHis: 1.069 ± 0.015	2.353LysIle: 2.353 ± 0.019	2.955LysLys: 2.955 ± 0.036	3.996LysLeu: 3.996 ± 0.028	0.865LysMet: 0.865 ± 0.013	1.538LysAsn: 1.538 ± 0.016	2.516LysPro: 2.516 ± 0.023	1.53LysGln: 1.53 ± 0.019	3.204LysArg: 3.204 ± 0.026	3.523LysSer: 3.523 ± 0.028	2.697LysThr: 2.697 ± 0.024	2.58LysVal: 2.58 ± 0.021	0.685LysTrp: 0.685 ± 0.012	1.231LysTyr: 1.231 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.809LeuAla: 7.809 ± 0.037	1.362LeuCys: 1.362 ± 0.019	5.383LeuAsp: 5.383 ± 0.034	5.699LeuGlu: 5.699 ± 0.041	3.641LeuPhe: 3.641 ± 0.032	5.657LeuGly: 5.657 ± 0.037	2.554LeuHis: 2.554 ± 0.023	4.689LeuIle: 4.689 ± 0.034	4.419LeuLys: 4.419 ± 0.031	9.185LeuLeu: 9.185 ± 0.056	1.748LeuMet: 1.748 ± 0.02	3.347LeuAsn: 3.347 ± 0.023	6.491LeuPro: 6.491 ± 0.038	3.794LeuGln: 3.794 ± 0.027	6.321LeuArg: 6.321 ± 0.04	8.862LeuSer: 8.862 ± 0.046	5.407LeuThr: 5.407 ± 0.037	5.718LeuVal: 5.718 ± 0.035	1.313LeuTrp: 1.313 ± 0.015	2.42LeuTyr: 2.42 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.747MetAla: 1.747 ± 0.017	0.231MetCys: 0.231 ± 0.007	1.167MetAsp: 1.167 ± 0.015	1.151MetGlu: 1.151 ± 0.015	0.71MetPhe: 0.71 ± 0.012	1.21MetGly: 1.21 ± 0.016	0.503MetHis: 0.503 ± 0.01	0.985MetIle: 0.985 ± 0.014	0.972MetLys: 0.972 ± 0.014	1.69MetLeu: 1.69 ± 0.016	0.484MetMet: 0.484 ± 0.01	0.748MetAsn: 0.748 ± 0.01	1.225MetPro: 1.225 ± 0.019	0.714MetGln: 0.714 ± 0.012	1.208MetArg: 1.208 ± 0.015	2.001MetSer: 2.001 ± 0.019	1.234MetThr: 1.234 ± 0.016	1.028MetVal: 1.028 ± 0.014	0.258MetTrp: 0.258 ± 0.007	0.443MetTyr: 0.443 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.034AsnAla: 3.034 ± 0.026	0.418AsnCys: 0.418 ± 0.01	1.77AsnAsp: 1.77 ± 0.021	1.893AsnGlu: 1.893 ± 0.019	1.36AsnPhe: 1.36 ± 0.017	2.508AsnGly: 2.508 ± 0.026	0.897AsnHis: 0.897 ± 0.012	2.058AsnIle: 2.058 ± 0.022	1.285AsnLys: 1.285 ± 0.015	3.392AsnLeu: 3.392 ± 0.025	0.699AsnMet: 0.699 ± 0.01	1.253AsnAsn: 1.253 ± 0.015	2.571AsnPro: 2.571 ± 0.023	1.192AsnGln: 1.192 ± 0.017	1.873AsnArg: 1.873 ± 0.02	2.776AsnSer: 2.776 ± 0.026	2.06AsnThr: 2.06 ± 0.02	2.375AsnVal: 2.375 ± 0.024	0.516AsnTrp: 0.516 ± 0.011	0.901AsnTyr: 0.901 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	4.995ProAla: 4.995 ± 0.041	0.535ProCys: 0.535 ± 0.01	3.403ProAsp: 3.403 ± 0.027	3.773ProGlu: 3.773 ± 0.029	2.415ProPhe: 2.415 ± 0.023	3.612ProGly: 3.612 ± 0.031	1.692ProHis: 1.692 ± 0.02	3.054ProIle: 3.054 ± 0.024	2.569ProLys: 2.569 ± 0.024	5.605ProLeu: 5.605 ± 0.032	1.043ProMet: 1.043 ± 0.015	2.382ProAsn: 2.382 ± 0.022	6.506ProPro: 6.506 ± 0.076	2.37ProGln: 2.37 ± 0.026	3.629ProArg: 3.629 ± 0.031	7.57ProSer: 7.57 ± 0.056	4.353ProThr: 4.353 ± 0.037	3.728ProVal: 3.728 ± 0.028	0.741ProTrp: 0.741 ± 0.011	1.582ProTyr: 1.582 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.086GlnAla: 3.086 ± 0.025	0.485GlnCys: 0.485 ± 0.009	1.904GlnAsp: 1.904 ± 0.019	2.115GlnGlu: 2.115 ± 0.023	1.332GlnPhe: 1.332 ± 0.015	2.029GlnGly: 2.029 ± 0.02	0.989GlnHis: 0.989 ± 0.015	1.988GlnIle: 1.988 ± 0.021	1.701GlnLys: 1.701 ± 0.018	3.349GlnLeu: 3.349 ± 0.029	0.739GlnMet: 0.739 ± 0.011	1.476GlnAsn: 1.476 ± 0.016	2.272GlnPro: 2.272 ± 0.027	1.637GlnGln: 1.637 ± 0.028	2.385GlnArg: 2.385 ± 0.022	3.332GlnSer: 3.332 ± 0.028	2.338GlnThr: 2.338 ± 0.021	2.048GlnVal: 2.048 ± 0.02	0.583GlnTrp: 0.583 ± 0.011	1.085GlnTyr: 1.085 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.706ArgAla: 4.706 ± 0.032	0.783ArgCys: 0.783 ± 0.014	3.333ArgAsp: 3.333 ± 0.024	3.717ArgGlu: 3.717 ± 0.032	2.251ArgPhe: 2.251 ± 0.021	3.445ArgGly: 3.445 ± 0.029	1.708ArgHis: 1.708 ± 0.018	3.22ArgIle: 3.22 ± 0.026	3.243ArgLys: 3.243 ± 0.029	5.914ArgLeu: 5.914 ± 0.043	1.294ArgMet: 1.294 ± 0.018	2.138ArgAsn: 2.138 ± 0.018	3.54ArgPro: 3.54 ± 0.03	2.263ArgGln: 2.263 ± 0.02	4.948ArgArg: 4.948 ± 0.039	5.328ArgSer: 5.328 ± 0.037	3.538ArgThr: 3.538 ± 0.026	3.557ArgVal: 3.557 ± 0.024	0.979ArgTrp: 0.979 ± 0.013	1.664ArgTyr: 1.664 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.879SerAla: 6.879 ± 0.038	0.967SerCys: 0.967 ± 0.016	4.65SerAsp: 4.65 ± 0.034	4.483SerGlu: 4.483 ± 0.033	3.526SerPhe: 3.526 ± 0.028	5.393SerGly: 5.393 ± 0.039	2.435SerHis: 2.435 ± 0.023	4.53SerIle: 4.53 ± 0.031	3.728SerLys: 3.728 ± 0.031	8.884SerLeu: 8.884 ± 0.049	1.692SerMet: 1.692 ± 0.019	3.149SerAsn: 3.149 ± 0.025	6.533SerPro: 6.533 ± 0.054	3.459SerGln: 3.459 ± 0.029	5.445SerArg: 5.445 ± 0.04	11.085SerSer: 11.085 ± 0.099	6.3SerThr: 6.3 ± 0.051	5.119SerVal: 5.119 ± 0.034	1.162SerTrp: 1.162 ± 0.016	2.143SerTyr: 2.143 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	4.706ThrAla: 4.706 ± 0.034	0.773ThrCys: 0.773 ± 0.013	2.788ThrAsp: 2.788 ± 0.022	2.961ThrGlu: 2.961 ± 0.025	2.498ThrPhe: 2.498 ± 0.024	3.617ThrGly: 3.617 ± 0.029	1.47ThrHis: 1.47 ± 0.018	3.249ThrIle: 3.249 ± 0.03	2.459ThrLys: 2.459 ± 0.021	6.053ThrLeu: 6.053 ± 0.037	1.11ThrMet: 1.11 ± 0.014	1.984ThrAsn: 1.984 ± 0.023	4.66ThrPro: 4.66 ± 0.039	2.057ThrGln: 2.057 ± 0.022	3.35ThrArg: 3.35 ± 0.028	6.173ThrSer: 6.173 ± 0.051	4.153ThrThr: 4.153 ± 0.04	3.652ThrVal: 3.652 ± 0.027	0.855ThrTrp: 0.855 ± 0.012	1.524ThrTyr: 1.524 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.11ValAla: 5.11 ± 0.034	0.813ValCys: 0.813 ± 0.013	3.7ValAsp: 3.7 ± 0.028	3.795ValGlu: 3.795 ± 0.026	2.463ValPhe: 2.463 ± 0.024	3.648ValGly: 3.648 ± 0.027	1.564ValHis: 1.564 ± 0.018	3.224ValIle: 3.224 ± 0.025	2.819ValLys: 2.819 ± 0.022	6.054ValLeu: 6.054 ± 0.035	1.23ValMet: 1.23 ± 0.014	2.103ValAsn: 2.103 ± 0.019	3.86ValPro: 3.86 ± 0.028	2.318ValGln: 2.318 ± 0.021	3.468ValArg: 3.468 ± 0.024	4.828ValSer: 4.828 ± 0.03	3.421ValThr: 3.421 ± 0.027	4.275ValVal: 4.275 ± 0.035	0.919ValTrp: 0.919 ± 0.013	1.621ValTyr: 1.621 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.055TrpAla: 1.055 ± 0.015	0.211TrpCys: 0.211 ± 0.007	0.938TrpAsp: 0.938 ± 0.014	0.863TrpGlu: 0.863 ± 0.014	0.555TrpPhe: 0.555 ± 0.011	0.836TrpGly: 0.836 ± 0.014	0.386TrpHis: 0.386 ± 0.009	0.891TrpIle: 0.891 ± 0.014	0.826TrpLys: 0.826 ± 0.011	1.319TrpLeu: 1.319 ± 0.016	0.377TrpMet: 0.377 ± 0.008	0.661TrpAsn: 0.661 ± 0.011	0.638TrpPro: 0.638 ± 0.011	0.525TrpGln: 0.525 ± 0.01	1.038TrpArg: 1.038 ± 0.014	1.204TrpSer: 1.204 ± 0.016	0.96TrpThr: 0.96 ± 0.014	0.824TrpVal: 0.824 ± 0.013	0.264TrpTrp: 0.264 ± 0.009	0.396TrpTyr: 0.396 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.94TyrAla: 1.94 ± 0.02	0.405TyrCys: 0.405 ± 0.009	1.541TyrAsp: 1.541 ± 0.017	1.448TyrGlu: 1.448 ± 0.016	1.104TyrPhe: 1.104 ± 0.015	1.733TyrGly: 1.733 ± 0.02	0.761TyrHis: 0.761 ± 0.012	1.408TyrIle: 1.408 ± 0.017	0.993TyrLys: 0.993 ± 0.015	2.632TyrLeu: 2.632 ± 0.024	0.561TyrMet: 0.561 ± 0.011	0.951TyrAsn: 0.951 ± 0.014	1.581TyrPro: 1.581 ± 0.021	1.01TyrGln: 1.01 ± 0.015	1.567TyrArg: 1.567 ± 0.018	2.057TyrSer: 2.057 ± 0.025	1.516TyrThr: 1.516 ± 0.019	1.592TyrVal: 1.592 ± 0.016	0.422TyrTrp: 0.422 ± 0.01	0.837TyrTyr: 0.837 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 13037 proteins (5547635 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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