Amino acid dipepetide frequency for Corynebacterium halotolerans YIM 70093 = DSM 44683

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.548AlaAla: 16.548 ± 0.186	0.825AlaCys: 0.825 ± 0.033	7.755AlaAsp: 7.755 ± 0.117	8.704AlaGlu: 8.704 ± 0.1	3.383AlaPhe: 3.383 ± 0.067	11.775AlaGly: 11.775 ± 0.135	2.425AlaHis: 2.425 ± 0.053	4.521AlaIle: 4.521 ± 0.085	2.562AlaLys: 2.562 ± 0.066	11.85AlaLeu: 11.85 ± 0.128	2.497AlaMet: 2.497 ± 0.057	2.187AlaAsn: 2.187 ± 0.056	5.613AlaPro: 5.613 ± 0.11	3.511AlaGln: 3.511 ± 0.076	8.12AlaArg: 8.12 ± 0.107	5.222AlaSer: 5.222 ± 0.078	7.108AlaThr: 7.108 ± 0.103	11.012AlaVal: 11.012 ± 0.145	1.669AlaTrp: 1.669 ± 0.042	2.119AlaTyr: 2.119 ± 0.054	0.001AlaXaa: 0.001 ± 0.001
Cys	0.665CysAla: 0.665 ± 0.026	0.045CysCys: 0.045 ± 0.007	0.387CysAsp: 0.387 ± 0.021	0.327CysGlu: 0.327 ± 0.021	0.196CysPhe: 0.196 ± 0.015	0.689CysGly: 0.689 ± 0.031	0.186CysHis: 0.186 ± 0.014	0.233CysIle: 0.233 ± 0.016	0.081CysLys: 0.081 ± 0.009	0.569CysLeu: 0.569 ± 0.022	0.088CysMet: 0.088 ± 0.01	0.147CysAsn: 0.147 ± 0.011	0.381CysPro: 0.381 ± 0.024	0.147CysGln: 0.147 ± 0.013	0.401CysArg: 0.401 ± 0.022	0.368CysSer: 0.368 ± 0.022	0.444CysThr: 0.444 ± 0.023	0.48CysVal: 0.48 ± 0.024	0.074CysTrp: 0.074 ± 0.008	0.104CysTyr: 0.104 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	7.542AspAla: 7.542 ± 0.098	0.327AspCys: 0.327 ± 0.02	4.057AspAsp: 4.057 ± 0.075	4.581AspGlu: 4.581 ± 0.079	1.928AspPhe: 1.928 ± 0.058	5.724AspGly: 5.724 ± 0.081	1.56AspHis: 1.56 ± 0.044	2.753AspIle: 2.753 ± 0.056	1.298AspLys: 1.298 ± 0.046	6.181AspLeu: 6.181 ± 0.095	1.12AspMet: 1.12 ± 0.038	1.531AspAsn: 1.531 ± 0.047	4.171AspPro: 4.171 ± 0.075	1.687AspGln: 1.687 ± 0.048	4.576AspArg: 4.576 ± 0.08	2.977AspSer: 2.977 ± 0.062	3.656AspThr: 3.656 ± 0.062	5.06AspVal: 5.06 ± 0.082	0.937AspTrp: 0.937 ± 0.037	1.356AspTyr: 1.356 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	6.923GluAla: 6.923 ± 0.087	0.28GluCys: 0.28 ± 0.019	3.821GluAsp: 3.821 ± 0.076	4.533GluGlu: 4.533 ± 0.097	2.034GluPhe: 2.034 ± 0.049	4.748GluGly: 4.748 ± 0.075	1.701GluHis: 1.701 ± 0.047	3.399GluIle: 3.399 ± 0.069	2.012GluLys: 2.012 ± 0.053	7.365GluLeu: 7.365 ± 0.11	1.277GluMet: 1.277 ± 0.042	1.824GluAsn: 1.824 ± 0.05	3.216GluPro: 3.216 ± 0.085	2.631GluGln: 2.631 ± 0.058	4.747GluArg: 4.747 ± 0.08	2.957GluSer: 2.957 ± 0.066	3.604GluThr: 3.604 ± 0.071	5.214GluVal: 5.214 ± 0.071	0.876GluTrp: 0.876 ± 0.033	1.324GluTyr: 1.324 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.66PheAla: 3.66 ± 0.08	0.196PheCys: 0.196 ± 0.015	2.298PheAsp: 2.298 ± 0.059	1.666PheGlu: 1.666 ± 0.048	1.132PhePhe: 1.132 ± 0.041	3.394PheGly: 3.394 ± 0.072	0.794PheHis: 0.794 ± 0.031	1.503PheIle: 1.503 ± 0.049	0.465PheLys: 0.465 ± 0.025	3.13PheLeu: 3.13 ± 0.067	0.565PheMet: 0.565 ± 0.027	0.828PheAsn: 0.828 ± 0.029	1.458PhePro: 1.458 ± 0.045	0.699PheGln: 0.699 ± 0.03	1.859PheArg: 1.859 ± 0.048	1.847PheSer: 1.847 ± 0.045	2.322PheThr: 2.322 ± 0.05	2.343PheVal: 2.343 ± 0.056	0.492PheTrp: 0.492 ± 0.025	0.716PheTyr: 0.716 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	9.446GlyAla: 9.446 ± 0.115	0.649GlyCys: 0.649 ± 0.027	5.133GlyAsp: 5.133 ± 0.083	6.024GlyGlu: 6.024 ± 0.098	3.05GlyPhe: 3.05 ± 0.059	7.763GlyGly: 7.763 ± 0.137	2.172GlyHis: 2.172 ± 0.054	4.319GlyIle: 4.319 ± 0.077	2.308GlyLys: 2.308 ± 0.054	9.237GlyLeu: 9.237 ± 0.12	2.36GlyMet: 2.36 ± 0.054	2.167GlyAsn: 2.167 ± 0.056	4.074GlyPro: 4.074 ± 0.071	2.86GlyGln: 2.86 ± 0.062	6.492GlyArg: 6.492 ± 0.084	5.011GlySer: 5.011 ± 0.074	5.916GlyThr: 5.916 ± 0.093	7.894GlyVal: 7.894 ± 0.098	1.595GlyTrp: 1.595 ± 0.042	2.19GlyTyr: 2.19 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.281HisAla: 2.281 ± 0.047	0.155HisCys: 0.155 ± 0.012	1.475HisAsp: 1.475 ± 0.041	1.29HisGlu: 1.29 ± 0.041	0.645HisPhe: 0.645 ± 0.027	2.201HisGly: 2.201 ± 0.054	0.754HisHis: 0.754 ± 0.032	0.886HisIle: 0.886 ± 0.028	0.355HisLys: 0.355 ± 0.021	2.429HisLeu: 2.429 ± 0.06	0.4HisMet: 0.4 ± 0.021	0.519HisAsn: 0.519 ± 0.026	1.699HisPro: 1.699 ± 0.043	0.681HisGln: 0.681 ± 0.03	1.9HisArg: 1.9 ± 0.044	1.148HisSer: 1.148 ± 0.034	1.255HisThr: 1.255 ± 0.039	1.687HisVal: 1.687 ± 0.041	0.309HisTrp: 0.309 ± 0.019	0.525HisTyr: 0.525 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.765IleAla: 5.765 ± 0.091	0.318IleCys: 0.318 ± 0.02	3.386IleAsp: 3.386 ± 0.064	2.713IleGlu: 2.713 ± 0.056	1.486IlePhe: 1.486 ± 0.048	4.394IleGly: 4.394 ± 0.082	0.991IleHis: 0.991 ± 0.032	2.233IleIle: 2.233 ± 0.056	0.859IleLys: 0.859 ± 0.036	3.974IleLeu: 3.974 ± 0.073	0.855IleMet: 0.855 ± 0.033	1.225IleAsn: 1.225 ± 0.044	2.456IlePro: 2.456 ± 0.054	1.073IleGln: 1.073 ± 0.037	2.865IleArg: 2.865 ± 0.064	2.33IleSer: 2.33 ± 0.05	3.022IleThr: 3.022 ± 0.053	3.768IleVal: 3.768 ± 0.069	0.552IleTrp: 0.552 ± 0.027	0.861IleTyr: 0.861 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	2.544LysAla: 2.544 ± 0.072	0.081LysCys: 0.081 ± 0.01	1.229LysAsp: 1.229 ± 0.044	1.321LysGlu: 1.321 ± 0.046	0.687LysPhe: 0.687 ± 0.026	1.685LysGly: 1.685 ± 0.052	0.441LysHis: 0.441 ± 0.019	1.16LysIle: 1.16 ± 0.042	1.108LysLys: 1.108 ± 0.048	2.286LysLeu: 2.286 ± 0.051	0.586LysMet: 0.586 ± 0.027	0.677LysAsn: 0.677 ± 0.027	1.138LysPro: 1.138 ± 0.039	0.736LysGln: 0.736 ± 0.034	1.532LysArg: 1.532 ± 0.043	1.16LysSer: 1.16 ± 0.04	1.324LysThr: 1.324 ± 0.045	1.876LysVal: 1.876 ± 0.045	0.312LysTrp: 0.312 ± 0.019	0.463LysTyr: 0.463 ± 0.026	0.0LysXaa: 0.0 ± 0.0
Leu	13.32LeuAla: 13.32 ± 0.132	0.633LeuCys: 0.633 ± 0.025	6.55LeuAsp: 6.55 ± 0.103	5.385LeuGlu: 5.385 ± 0.099	2.903LeuPhe: 2.903 ± 0.064	9.265LeuGly: 9.265 ± 0.11	2.145LeuHis: 2.145 ± 0.049	4.817LeuIle: 4.817 ± 0.081	2.067LeuLys: 2.067 ± 0.054	10.077LeuLeu: 10.077 ± 0.145	1.948LeuMet: 1.948 ± 0.051	2.331LeuAsn: 2.331 ± 0.054	5.745LeuPro: 5.745 ± 0.088	2.505LeuGln: 2.505 ± 0.058	7.123LeuArg: 7.123 ± 0.09	5.792LeuSer: 5.792 ± 0.087	6.54LeuThr: 6.54 ± 0.089	8.567LeuVal: 8.567 ± 0.121	1.232LeuTrp: 1.232 ± 0.041	1.675LeuTyr: 1.675 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.549MetAla: 2.549 ± 0.053	0.12MetCys: 0.12 ± 0.011	1.098MetAsp: 1.098 ± 0.037	1.018MetGlu: 1.018 ± 0.032	0.677MetPhe: 0.677 ± 0.027	1.61MetGly: 1.61 ± 0.046	0.378MetHis: 0.378 ± 0.021	1.121MetIle: 1.121 ± 0.033	0.565MetLys: 0.565 ± 0.028	2.166MetLeu: 2.166 ± 0.051	0.451MetMet: 0.451 ± 0.029	0.607MetAsn: 0.607 ± 0.027	1.143MetPro: 1.143 ± 0.035	0.501MetGln: 0.501 ± 0.021	1.304MetArg: 1.304 ± 0.04	1.616MetSer: 1.616 ± 0.038	1.83MetThr: 1.83 ± 0.043	1.638MetVal: 1.638 ± 0.044	0.256MetTrp: 0.256 ± 0.018	0.332MetTyr: 0.332 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.588AsnAla: 2.588 ± 0.055	0.162AsnCys: 0.162 ± 0.013	1.295AsnAsp: 1.295 ± 0.041	1.379AsnGlu: 1.379 ± 0.042	0.818AsnPhe: 0.818 ± 0.03	1.937AsnGly: 1.937 ± 0.05	0.558AsnHis: 0.558 ± 0.024	1.169AsnIle: 1.169 ± 0.037	0.563AsnLys: 0.563 ± 0.028	2.425AsnLeu: 2.425 ± 0.049	0.492AsnMet: 0.492 ± 0.021	0.661AsnAsn: 0.661 ± 0.033	1.895AsnPro: 1.895 ± 0.046	0.783AsnGln: 0.783 ± 0.033	1.643AsnArg: 1.643 ± 0.045	1.283AsnSer: 1.283 ± 0.042	1.389AsnThr: 1.389 ± 0.037	1.672AsnVal: 1.672 ± 0.049	0.395AsnTrp: 0.395 ± 0.017	0.601AsnTyr: 0.601 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.882ProAla: 6.882 ± 0.111	0.207ProCys: 0.207 ± 0.016	3.974ProAsp: 3.974 ± 0.078	4.836ProGlu: 4.836 ± 0.09	1.565ProPhe: 1.565 ± 0.041	5.551ProGly: 5.551 ± 0.084	1.126ProHis: 1.126 ± 0.037	1.608ProIle: 1.608 ± 0.04	1.161ProLys: 1.161 ± 0.046	4.684ProLeu: 4.684 ± 0.081	0.994ProMet: 0.994 ± 0.033	1.183ProAsn: 1.183 ± 0.041	2.137ProPro: 2.137 ± 0.063	1.68ProGln: 1.68 ± 0.046	3.231ProArg: 3.231 ± 0.068	2.593ProSer: 2.593 ± 0.054	3.376ProThr: 3.376 ± 0.068	5.358ProVal: 5.358 ± 0.083	0.81ProTrp: 0.81 ± 0.034	1.059ProTyr: 1.059 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.653GlnAla: 3.653 ± 0.07	0.11GlnCys: 0.11 ± 0.013	1.372GlnAsp: 1.372 ± 0.042	1.693GlnGlu: 1.693 ± 0.048	0.931GlnPhe: 0.931 ± 0.035	2.132GlnGly: 2.132 ± 0.05	0.543GlnHis: 0.543 ± 0.023	1.478GlnIle: 1.478 ± 0.041	0.656GlnLys: 0.656 ± 0.029	3.552GlnLeu: 3.552 ± 0.079	0.726GlnMet: 0.726 ± 0.028	0.69GlnAsn: 0.69 ± 0.029	1.566GlnPro: 1.566 ± 0.043	1.208GlnGln: 1.208 ± 0.051	2.257GlnArg: 2.257 ± 0.054	1.337GlnSer: 1.337 ± 0.042	1.454GlnThr: 1.454 ± 0.042	2.66GlnVal: 2.66 ± 0.055	0.463GlnTrp: 0.463 ± 0.026	0.53GlnTyr: 0.53 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	7.424ArgAla: 7.424 ± 0.113	0.343ArgCys: 0.343 ± 0.02	4.267ArgAsp: 4.267 ± 0.072	5.011ArgGlu: 5.011 ± 0.08	2.232ArgPhe: 2.232 ± 0.052	5.435ArgGly: 5.435 ± 0.092	1.764ArgHis: 1.764 ± 0.047	3.451ArgIle: 3.451 ± 0.067	1.791ArgLys: 1.791 ± 0.051	7.044ArgLeu: 7.044 ± 0.104	1.882ArgMet: 1.882 ± 0.04	1.674ArgAsn: 1.674 ± 0.039	3.624ArgPro: 3.624 ± 0.059	2.307ArgGln: 2.307 ± 0.057	6.47ArgArg: 6.47 ± 0.117	3.627ArgSer: 3.627 ± 0.057	4.103ArgThr: 4.103 ± 0.078	5.256ArgVal: 5.256 ± 0.076	1.086ArgTrp: 1.086 ± 0.035	1.555ArgTyr: 1.555 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.881SerAla: 5.881 ± 0.093	0.317SerCys: 0.317 ± 0.019	2.877SerAsp: 2.877 ± 0.053	3.006SerGlu: 3.006 ± 0.061	1.791SerPhe: 1.791 ± 0.048	5.648SerGly: 5.648 ± 0.08	1.109SerHis: 1.109 ± 0.039	2.065SerIle: 2.065 ± 0.045	1.083SerLys: 1.083 ± 0.034	4.935SerLeu: 4.935 ± 0.069	1.225SerMet: 1.225 ± 0.044	1.168SerAsn: 1.168 ± 0.038	3.074SerPro: 3.074 ± 0.061	1.491SerGln: 1.491 ± 0.042	3.716SerArg: 3.716 ± 0.07	3.141SerSer: 3.141 ± 0.068	3.473SerThr: 3.473 ± 0.058	4.381SerVal: 4.381 ± 0.073	0.87SerTrp: 0.87 ± 0.03	1.165SerTyr: 1.165 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	7.686ThrAla: 7.686 ± 0.097	0.424ThrCys: 0.424 ± 0.023	3.978ThrAsp: 3.978 ± 0.071	3.631ThrGlu: 3.631 ± 0.064	1.891ThrPhe: 1.891 ± 0.055	6.734ThrGly: 6.734 ± 0.086	1.311ThrHis: 1.311 ± 0.035	2.585ThrIle: 2.585 ± 0.056	1.158ThrLys: 1.158 ± 0.038	5.728ThrLeu: 5.728 ± 0.082	1.174ThrMet: 1.174 ± 0.035	1.248ThrAsn: 1.248 ± 0.039	4.145ThrPro: 4.145 ± 0.076	1.481ThrGln: 1.481 ± 0.042	3.985ThrArg: 3.985 ± 0.068	3.245ThrSer: 3.245 ± 0.067	4.416ThrThr: 4.416 ± 0.086	6.273ThrVal: 6.273 ± 0.094	0.964ThrTrp: 0.964 ± 0.035	1.251ThrTyr: 1.251 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	10.35ValAla: 10.35 ± 0.132	0.566ValCys: 0.566 ± 0.024	6.029ValAsp: 6.029 ± 0.099	5.416ValGlu: 5.416 ± 0.085	2.675ValPhe: 2.675 ± 0.06	7.015ValGly: 7.015 ± 0.105	1.885ValHis: 1.885 ± 0.045	4.346ValIle: 4.346 ± 0.074	1.596ValLys: 1.596 ± 0.043	8.861ValLeu: 8.861 ± 0.096	1.689ValMet: 1.689 ± 0.047	2.096ValAsn: 2.096 ± 0.052	4.663ValPro: 4.663 ± 0.076	1.888ValGln: 1.888 ± 0.05	5.331ValArg: 5.331 ± 0.071	4.716ValSer: 4.716 ± 0.071	6.053ValThr: 6.053 ± 0.075	8.011ValVal: 8.011 ± 0.126	1.08ValTrp: 1.08 ± 0.035	1.498ValTyr: 1.498 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	1.645TrpAla: 1.645 ± 0.038	0.101TrpCys: 0.101 ± 0.011	0.773TrpAsp: 0.773 ± 0.031	0.775TrpGlu: 0.775 ± 0.029	0.582TrpPhe: 0.582 ± 0.026	1.023TrpGly: 1.023 ± 0.037	0.314TrpHis: 0.314 ± 0.02	0.71TrpIle: 0.71 ± 0.027	0.319TrpLys: 0.319 ± 0.018	1.849TrpLeu: 1.849 ± 0.054	0.352TrpMet: 0.352 ± 0.017	0.409TrpAsn: 0.409 ± 0.022	0.691TrpPro: 0.691 ± 0.032	0.493TrpGln: 0.493 ± 0.022	1.151TrpArg: 1.151 ± 0.036	0.791TrpSer: 0.791 ± 0.029	0.852TrpThr: 0.852 ± 0.031	1.166TrpVal: 1.166 ± 0.043	0.393TrpTrp: 0.393 ± 0.02	0.305TrpTyr: 0.305 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.053TyrAla: 2.053 ± 0.046	0.154TyrCys: 0.154 ± 0.013	1.268TyrAsp: 1.268 ± 0.041	1.177TyrGlu: 1.177 ± 0.037	0.762TyrPhe: 0.762 ± 0.032	1.937TyrGly: 1.937 ± 0.051	0.436TyrHis: 0.436 ± 0.021	0.773TyrIle: 0.773 ± 0.029	0.342TyrLys: 0.342 ± 0.021	2.277TyrLeu: 2.277 ± 0.059	0.299TyrMet: 0.299 ± 0.019	0.536TyrAsn: 0.536 ± 0.026	1.128TyrPro: 1.128 ± 0.036	0.649TyrGln: 0.649 ± 0.03	1.64TyrArg: 1.64 ± 0.041	1.256TyrSer: 1.256 ± 0.037	1.171TyrThr: 1.171 ± 0.04	1.447TyrVal: 1.447 ± 0.044	0.327TyrTrp: 0.327 ± 0.019	0.471TyrTyr: 0.471 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2853 proteins (924155 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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