Amino acid dipepetide frequency for Marinicella litoralis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.322AlaAla: 7.322 ± 0.109	0.865AlaCys: 0.865 ± 0.028	4.783AlaAsp: 4.783 ± 0.067	5.212AlaGlu: 5.212 ± 0.075	3.314AlaPhe: 3.314 ± 0.062	5.9AlaGly: 5.9 ± 0.096	1.673AlaHis: 1.673 ± 0.044	5.531AlaIle: 5.531 ± 0.072	4.565AlaLys: 4.565 ± 0.081	8.115AlaLeu: 8.115 ± 0.111	2.404AlaMet: 2.404 ± 0.055	3.685AlaAsn: 3.685 ± 0.077	2.471AlaPro: 2.471 ± 0.063	3.657AlaGln: 3.657 ± 0.071	2.706AlaArg: 2.706 ± 0.053	4.694AlaSer: 4.694 ± 0.08	4.346AlaThr: 4.346 ± 0.086	5.791AlaVal: 5.791 ± 0.094	1.039AlaTrp: 1.039 ± 0.033	2.394AlaTyr: 2.394 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.67CysAla: 0.67 ± 0.03	0.133CysCys: 0.133 ± 0.013	0.663CysAsp: 0.663 ± 0.031	0.595CysGlu: 0.595 ± 0.025	0.419CysPhe: 0.419 ± 0.023	0.824CysGly: 0.824 ± 0.035	0.356CysHis: 0.356 ± 0.023	0.506CysIle: 0.506 ± 0.026	0.357CysLys: 0.357 ± 0.022	0.9CysLeu: 0.9 ± 0.03	0.2CysMet: 0.2 ± 0.015	0.379CysAsn: 0.379 ± 0.02	0.401CysPro: 0.401 ± 0.022	0.561CysGln: 0.561 ± 0.025	0.34CysArg: 0.34 ± 0.022	0.611CysSer: 0.611 ± 0.029	0.502CysThr: 0.502 ± 0.027	0.584CysVal: 0.584 ± 0.026	0.101CysTrp: 0.101 ± 0.011	0.294CysTyr: 0.294 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.387AspAla: 4.387 ± 0.081	0.585AspCys: 0.585 ± 0.028	3.616AspAsp: 3.616 ± 0.073	3.946AspGlu: 3.946 ± 0.074	2.937AspPhe: 2.937 ± 0.065	4.131AspGly: 4.131 ± 0.102	1.506AspHis: 1.506 ± 0.044	3.723AspIle: 3.723 ± 0.066	2.724AspLys: 2.724 ± 0.058	6.194AspLeu: 6.194 ± 0.088	1.511AspMet: 1.511 ± 0.044	2.708AspAsn: 2.708 ± 0.061	2.405AspPro: 2.405 ± 0.056	3.217AspGln: 3.217 ± 0.057	2.269AspArg: 2.269 ± 0.048	3.359AspSer: 3.359 ± 0.066	2.523AspThr: 2.523 ± 0.059	4.191AspVal: 4.191 ± 0.077	0.918AspTrp: 0.918 ± 0.037	2.115AspTyr: 2.115 ± 0.051	0.0AspXaa: 0.0 ± 0.0
Glu	4.502GluAla: 4.502 ± 0.078	0.384GluCys: 0.384 ± 0.021	2.8GluAsp: 2.8 ± 0.056	2.675GluGlu: 2.675 ± 0.068	2.475GluPhe: 2.475 ± 0.053	2.893GluGly: 2.893 ± 0.06	1.333GluHis: 1.333 ± 0.039	4.034GluIle: 4.034 ± 0.073	3.597GluLys: 3.597 ± 0.077	6.101GluLeu: 6.101 ± 0.105	1.595GluMet: 1.595 ± 0.038	3.067GluAsn: 3.067 ± 0.054	1.919GluPro: 1.919 ± 0.045	3.305GluGln: 3.305 ± 0.064	2.201GluArg: 2.201 ± 0.052	3.662GluSer: 3.662 ± 0.058	2.961GluThr: 2.961 ± 0.057	4.075GluVal: 4.075 ± 0.069	0.62GluTrp: 0.62 ± 0.026	1.691GluTyr: 1.691 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	3.327PheAla: 3.327 ± 0.058	0.454PheCys: 0.454 ± 0.022	3.191PheAsp: 3.191 ± 0.07	2.678PheGlu: 2.678 ± 0.05	1.902PhePhe: 1.902 ± 0.054	3.144PheGly: 3.144 ± 0.057	0.85PheHis: 0.85 ± 0.029	3.012PheIle: 3.012 ± 0.067	2.678PheLys: 2.678 ± 0.062	3.688PheLeu: 3.688 ± 0.07	1.114PheMet: 1.114 ± 0.039	2.72PheAsn: 2.72 ± 0.052	1.484PhePro: 1.484 ± 0.043	1.492PheGln: 1.492 ± 0.039	1.379PheArg: 1.379 ± 0.036	3.324PheSer: 3.324 ± 0.067	2.396PheThr: 2.396 ± 0.059	2.786PheVal: 2.786 ± 0.057	0.569PheTrp: 0.569 ± 0.027	1.538PheTyr: 1.538 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.777GlyAla: 4.777 ± 0.095	0.728GlyCys: 0.728 ± 0.03	3.901GlyAsp: 3.901 ± 0.08	3.541GlyGlu: 3.541 ± 0.063	3.603GlyPhe: 3.603 ± 0.06	5.133GlyGly: 5.133 ± 0.114	1.775GlyHis: 1.775 ± 0.052	4.548GlyIle: 4.548 ± 0.077	3.418GlyLys: 3.418 ± 0.077	6.849GlyLeu: 6.849 ± 0.094	2.099GlyMet: 2.099 ± 0.052	2.947GlyAsn: 2.947 ± 0.087	1.81GlyPro: 1.81 ± 0.054	3.297GlyGln: 3.297 ± 0.07	2.53GlyArg: 2.53 ± 0.06	4.529GlySer: 4.529 ± 0.098	3.676GlyThr: 3.676 ± 0.091	4.99GlyVal: 4.99 ± 0.087	0.962GlyTrp: 0.962 ± 0.032	2.272GlyTyr: 2.272 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	1.807HisAla: 1.807 ± 0.042	0.287HisCys: 0.287 ± 0.018	1.301HisAsp: 1.301 ± 0.037	1.319HisGlu: 1.319 ± 0.038	1.159HisPhe: 1.159 ± 0.04	1.607HisGly: 1.607 ± 0.04	0.784HisHis: 0.784 ± 0.028	1.574HisIle: 1.574 ± 0.044	1.132HisLys: 1.132 ± 0.033	2.441HisLeu: 2.441 ± 0.058	0.579HisMet: 0.579 ± 0.023	1.019HisAsn: 1.019 ± 0.032	1.231HisPro: 1.231 ± 0.035	1.509HisGln: 1.509 ± 0.042	1.014HisArg: 1.014 ± 0.032	1.379HisSer: 1.379 ± 0.043	0.962HisThr: 0.962 ± 0.032	1.582HisVal: 1.582 ± 0.036	0.412HisTrp: 0.412 ± 0.022	0.866HisTyr: 0.866 ± 0.031	0.0HisXaa: 0.0 ± 0.0
Ile	5.154IleAla: 5.154 ± 0.091	0.606IleCys: 0.606 ± 0.027	4.884IleAsp: 4.884 ± 0.079	4.908IleGlu: 4.908 ± 0.076	2.271IlePhe: 2.271 ± 0.045	4.387IleGly: 4.387 ± 0.075	1.527IleHis: 1.527 ± 0.042	4.136IleIle: 4.136 ± 0.072	5.025IleLys: 5.025 ± 0.09	5.227IleLeu: 5.227 ± 0.09	1.484IleMet: 1.484 ± 0.037	4.554IleAsn: 4.554 ± 0.07	2.729IlePro: 2.729 ± 0.05	2.895IleGln: 2.895 ± 0.061	2.483IleArg: 2.483 ± 0.057	4.703IleSer: 4.703 ± 0.085	3.993IleThr: 3.993 ± 0.065	3.533IleVal: 3.533 ± 0.065	0.702IleTrp: 0.702 ± 0.032	2.021IleTyr: 2.021 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	4.658LysAla: 4.658 ± 0.087	0.309LysCys: 0.309 ± 0.024	2.982LysAsp: 2.982 ± 0.065	2.835LysGlu: 2.835 ± 0.072	1.825LysPhe: 1.825 ± 0.042	3.042LysGly: 3.042 ± 0.06	1.538LysHis: 1.538 ± 0.04	3.842LysIle: 3.842 ± 0.079	3.737LysLys: 3.737 ± 0.093	5.222LysLeu: 5.222 ± 0.077	1.548LysMet: 1.548 ± 0.05	3.137LysAsn: 3.137 ± 0.06	2.503LysPro: 2.503 ± 0.066	3.527LysGln: 3.527 ± 0.075	2.337LysArg: 2.337 ± 0.056	3.913LysSer: 3.913 ± 0.076	3.48LysThr: 3.48 ± 0.069	3.608LysVal: 3.608 ± 0.073	0.639LysTrp: 0.639 ± 0.029	1.668LysTyr: 1.668 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	8.572LeuAla: 8.572 ± 0.118	0.931LeuCys: 0.931 ± 0.032	5.476LeuAsp: 5.476 ± 0.076	4.771LeuGlu: 4.771 ± 0.087	4.444LeuPhe: 4.444 ± 0.086	6.257LeuGly: 6.257 ± 0.101	1.888LeuHis: 1.888 ± 0.043	7.152LeuIle: 7.152 ± 0.101	6.157LeuLys: 6.157 ± 0.094	10.42LeuLeu: 10.42 ± 0.173	2.916LeuMet: 2.916 ± 0.056	5.514LeuAsn: 5.514 ± 0.089	4.214LeuPro: 4.214 ± 0.076	3.814LeuGln: 3.814 ± 0.07	3.411LeuArg: 3.411 ± 0.068	7.488LeuSer: 7.488 ± 0.099	5.856LeuThr: 5.856 ± 0.087	6.55LeuVal: 6.55 ± 0.105	1.145LeuTrp: 1.145 ± 0.036	2.74LeuTyr: 2.74 ± 0.058	0.0LeuXaa: 0.0 ± 0.0
Met	2.752MetAla: 2.752 ± 0.062	0.198MetCys: 0.198 ± 0.015	1.365MetAsp: 1.365 ± 0.04	1.151MetGlu: 1.151 ± 0.036	0.896MetPhe: 0.896 ± 0.031	1.892MetGly: 1.892 ± 0.044	0.525MetHis: 0.525 ± 0.023	1.746MetIle: 1.746 ± 0.04	1.877MetLys: 1.877 ± 0.051	2.64MetLeu: 2.64 ± 0.06	0.873MetMet: 0.873 ± 0.032	1.509MetAsn: 1.509 ± 0.037	1.185MetPro: 1.185 ± 0.036	1.136MetGln: 1.136 ± 0.032	0.973MetArg: 0.973 ± 0.031	1.844MetSer: 1.844 ± 0.044	1.712MetThr: 1.712 ± 0.04	1.965MetVal: 1.965 ± 0.044	0.239MetTrp: 0.239 ± 0.016	0.592MetTyr: 0.592 ± 0.022	0.0MetXaa: 0.0 ± 0.0
Asn	3.546AsnAla: 3.546 ± 0.063	0.466AsnCys: 0.466 ± 0.024	3.126AsnAsp: 3.126 ± 0.07	2.834AsnGlu: 2.834 ± 0.057	1.815AsnPhe: 1.815 ± 0.05	3.689AsnGly: 3.689 ± 0.088	1.595AsnHis: 1.595 ± 0.042	3.178AsnIle: 3.178 ± 0.058	2.941AsnLys: 2.941 ± 0.071	4.577AsnLeu: 4.577 ± 0.079	1.11AsnMet: 1.11 ± 0.034	3.313AsnAsn: 3.313 ± 0.086	2.623AsnPro: 2.623 ± 0.046	3.673AsnGln: 3.673 ± 0.076	2.228AsnArg: 2.228 ± 0.054	3.163AsnSer: 3.163 ± 0.071	2.8AsnThr: 2.8 ± 0.066	2.729AsnVal: 2.729 ± 0.055	0.742AsnTrp: 0.742 ± 0.033	1.567AsnTyr: 1.567 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	3.136ProAla: 3.136 ± 0.064	0.279ProCys: 0.279 ± 0.016	2.56ProAsp: 2.56 ± 0.047	2.903ProGlu: 2.903 ± 0.059	1.833ProPhe: 1.833 ± 0.044	2.59ProGly: 2.59 ± 0.064	0.827ProHis: 0.827 ± 0.028	2.537ProIle: 2.537 ± 0.049	1.986ProLys: 1.986 ± 0.049	3.577ProLeu: 3.577 ± 0.063	1.079ProMet: 1.079 ± 0.034	2.049ProAsn: 2.049 ± 0.051	1.24ProPro: 1.24 ± 0.045	1.634ProGln: 1.634 ± 0.04	1.12ProArg: 1.12 ± 0.033	2.354ProSer: 2.354 ± 0.051	2.086ProThr: 2.086 ± 0.047	2.978ProVal: 2.978 ± 0.054	0.516ProTrp: 0.516 ± 0.026	1.188ProTyr: 1.188 ± 0.033	0.0ProXaa: 0.0 ± 0.0
Gln	4.598GlnAla: 4.598 ± 0.083	0.427GlnCys: 0.427 ± 0.02	2.176GlnAsp: 2.176 ± 0.053	1.927GlnGlu: 1.927 ± 0.045	2.099GlnPhe: 2.099 ± 0.046	2.952GlnGly: 2.952 ± 0.051	1.27GlnHis: 1.27 ± 0.04	3.374GlnIle: 3.374 ± 0.064	2.601GlnLys: 2.601 ± 0.054	5.859GlnLeu: 5.859 ± 0.101	1.373GlnMet: 1.373 ± 0.038	2.363GlnAsn: 2.363 ± 0.057	1.819GlnPro: 1.819 ± 0.048	3.459GlnGln: 3.459 ± 0.08	1.832GlnArg: 1.832 ± 0.05	3.457GlnSer: 3.457 ± 0.056	2.597GlnThr: 2.597 ± 0.059	3.632GlnVal: 3.632 ± 0.064	0.882GlnTrp: 0.882 ± 0.031	1.506GlnTyr: 1.506 ± 0.044	0.0GlnXaa: 0.0 ± 0.0
Arg	2.595ArgAla: 2.595 ± 0.057	0.378ArgCys: 0.378 ± 0.019	1.879ArgAsp: 1.879 ± 0.052	1.842ArgGlu: 1.842 ± 0.045	1.851ArgPhe: 1.851 ± 0.046	2.244ArgGly: 2.244 ± 0.049	0.928ArgHis: 0.928 ± 0.031	2.745ArgIle: 2.745 ± 0.055	2.218ArgLys: 2.218 ± 0.056	3.912ArgLeu: 3.912 ± 0.074	1.136ArgMet: 1.136 ± 0.036	1.904ArgAsn: 1.904 ± 0.043	1.314ArgPro: 1.314 ± 0.038	1.729ArgGln: 1.729 ± 0.045	1.658ArgArg: 1.658 ± 0.052	2.325ArgSer: 2.325 ± 0.052	1.884ArgThr: 1.884 ± 0.048	2.477ArgVal: 2.477 ± 0.056	0.535ArgTrp: 0.535 ± 0.023	1.333ArgTyr: 1.333 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	5.081SerAla: 5.081 ± 0.08	0.703SerCys: 0.703 ± 0.031	3.833SerAsp: 3.833 ± 0.078	3.591SerGlu: 3.591 ± 0.067	2.966SerPhe: 2.966 ± 0.058	5.24SerGly: 5.24 ± 0.107	1.679SerHis: 1.679 ± 0.046	4.456SerIle: 4.456 ± 0.071	3.294SerLys: 3.294 ± 0.06	6.405SerLeu: 6.405 ± 0.085	1.87SerMet: 1.87 ± 0.041	3.211SerAsn: 3.211 ± 0.073	2.477SerPro: 2.477 ± 0.057	3.242SerGln: 3.242 ± 0.062	2.432SerArg: 2.432 ± 0.054	4.208SerSer: 4.208 ± 0.088	3.52SerThr: 3.52 ± 0.066	4.415SerVal: 4.415 ± 0.081	0.964SerTrp: 0.964 ± 0.034	2.203SerTyr: 2.203 ± 0.051	0.0SerXaa: 0.0 ± 0.0
Thr	4.886ThrAla: 4.886 ± 0.089	0.494ThrCys: 0.494 ± 0.025	3.468ThrAsp: 3.468 ± 0.069	3.299ThrGlu: 3.299 ± 0.056	2.264ThrPhe: 2.264 ± 0.057	4.422ThrGly: 4.422 ± 0.093	1.358ThrHis: 1.358 ± 0.038	3.612ThrIle: 3.612 ± 0.07	2.232ThrLys: 2.232 ± 0.048	5.471ThrLeu: 5.471 ± 0.083	1.207ThrMet: 1.207 ± 0.036	2.297ThrAsn: 2.297 ± 0.061	2.469ThrPro: 2.469 ± 0.046	2.593ThrGln: 2.593 ± 0.05	1.694ThrArg: 1.694 ± 0.042	3.203ThrSer: 3.203 ± 0.071	3.113ThrThr: 3.113 ± 0.066	3.941ThrVal: 3.941 ± 0.081	0.74ThrTrp: 0.74 ± 0.028	1.568ThrTyr: 1.568 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	5.695ValAla: 5.695 ± 0.102	0.689ValCys: 0.689 ± 0.03	4.354ValAsp: 4.354 ± 0.073	3.75ValGlu: 3.75 ± 0.058	3.279ValPhe: 3.279 ± 0.064	4.249ValGly: 4.249 ± 0.075	1.286ValHis: 1.286 ± 0.043	4.993ValIle: 4.993 ± 0.078	3.859ValLys: 3.859 ± 0.074	6.871ValLeu: 6.871 ± 0.097	1.952ValMet: 1.952 ± 0.046	3.546ValAsn: 3.546 ± 0.065	2.395ValPro: 2.395 ± 0.051	2.212ValGln: 2.212 ± 0.047	2.263ValArg: 2.263 ± 0.05	4.681ValSer: 4.681 ± 0.078	3.801ValThr: 3.801 ± 0.08	5.3ValVal: 5.3 ± 0.088	0.796ValTrp: 0.796 ± 0.029	2.068ValTyr: 2.068 ± 0.051	0.0ValXaa: 0.0 ± 0.0
Trp	0.755TrpAla: 0.755 ± 0.027	0.138TrpCys: 0.138 ± 0.009	0.642TrpAsp: 0.642 ± 0.027	0.527TrpGlu: 0.527 ± 0.022	0.727TrpPhe: 0.727 ± 0.032	0.74TrpGly: 0.74 ± 0.026	0.4TrpHis: 0.4 ± 0.021	0.812TrpIle: 0.812 ± 0.031	0.519TrpLys: 0.519 ± 0.023	1.838TrpLeu: 1.838 ± 0.052	0.375TrpMet: 0.375 ± 0.023	0.529TrpAsn: 0.529 ± 0.024	0.48TrpPro: 0.48 ± 0.026	1.024TrpGln: 1.024 ± 0.033	0.569TrpArg: 0.569 ± 0.024	0.89TrpSer: 0.89 ± 0.035	0.61TrpThr: 0.61 ± 0.028	1.066TrpVal: 1.066 ± 0.037	0.189TrpTrp: 0.189 ± 0.014	0.415TrpTyr: 0.415 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.248TyrAla: 2.248 ± 0.049	0.345TyrCys: 0.345 ± 0.017	1.962TyrAsp: 1.962 ± 0.066	1.588TyrGlu: 1.588 ± 0.039	1.647TyrPhe: 1.647 ± 0.036	2.047TyrGly: 2.047 ± 0.047	0.868TyrHis: 0.868 ± 0.032	1.707TyrIle: 1.707 ± 0.041	1.432TyrLys: 1.432 ± 0.044	3.408TyrLeu: 3.408 ± 0.059	0.645TyrMet: 0.645 ± 0.027	1.265TyrAsn: 1.265 ± 0.043	1.305TyrPro: 1.305 ± 0.035	2.23TyrGln: 2.23 ± 0.045	1.449TyrArg: 1.449 ± 0.041	2.003TyrSer: 2.003 ± 0.051	1.51TyrThr: 1.51 ± 0.044	1.842TyrVal: 1.842 ± 0.049	0.535TyrTrp: 0.535 ± 0.022	1.135TyrTyr: 1.135 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2897 proteins (1015597 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---