Amino acid dipepetide frequency for Phenylobacterium deserti

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.665AlaAla: 21.665 ± 0.219	1.147AlaCys: 1.147 ± 0.033	7.387AlaAsp: 7.387 ± 0.096	8.68AlaGlu: 8.68 ± 0.105	4.829AlaPhe: 4.829 ± 0.066	12.124AlaGly: 12.124 ± 0.134	2.297AlaHis: 2.297 ± 0.04	5.198AlaIle: 5.198 ± 0.079	3.923AlaLys: 3.923 ± 0.068	14.335AlaLeu: 14.335 ± 0.149	3.339AlaMet: 3.339 ± 0.054	2.872AlaAsn: 2.872 ± 0.06	7.714AlaPro: 7.714 ± 0.12	5.258AlaGln: 5.258 ± 0.087	10.571AlaArg: 10.571 ± 0.103	6.873AlaSer: 6.873 ± 0.098	5.796AlaThr: 5.796 ± 0.08	9.74AlaVal: 9.74 ± 0.104	1.946AlaTrp: 1.946 ± 0.047	2.764AlaTyr: 2.764 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.025CysAla: 1.025 ± 0.031	0.079CysCys: 0.079 ± 0.009	0.485CysAsp: 0.485 ± 0.021	0.455CysGlu: 0.455 ± 0.022	0.245CysPhe: 0.245 ± 0.015	0.803CysGly: 0.803 ± 0.029	0.161CysHis: 0.161 ± 0.012	0.264CysIle: 0.264 ± 0.017	0.154CysLys: 0.154 ± 0.013	0.633CysLeu: 0.633 ± 0.024	0.124CysMet: 0.124 ± 0.011	0.156CysAsn: 0.156 ± 0.011	0.384CysPro: 0.384 ± 0.02	0.205CysGln: 0.205 ± 0.015	0.517CysArg: 0.517 ± 0.024	0.36CysSer: 0.36 ± 0.02	0.374CysThr: 0.374 ± 0.019	0.558CysVal: 0.558 ± 0.023	0.093CysTrp: 0.093 ± 0.009	0.143CysTyr: 0.143 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.301AspAla: 7.301 ± 0.091	0.359AspCys: 0.359 ± 0.017	2.884AspAsp: 2.884 ± 0.063	3.541AspGlu: 3.541 ± 0.056	2.064AspPhe: 2.064 ± 0.043	5.107AspGly: 5.107 ± 0.071	1.085AspHis: 1.085 ± 0.031	2.24AspIle: 2.24 ± 0.042	1.399AspLys: 1.399 ± 0.034	6.32AspLeu: 6.32 ± 0.08	1.063AspMet: 1.063 ± 0.031	1.148AspAsn: 1.148 ± 0.033	3.864AspPro: 3.864 ± 0.062	1.898AspGln: 1.898 ± 0.038	4.373AspArg: 4.373 ± 0.062	1.887AspSer: 1.887 ± 0.041	2.216AspThr: 2.216 ± 0.05	4.252AspVal: 4.252 ± 0.065	1.008AspTrp: 1.008 ± 0.032	1.387AspTyr: 1.387 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	9.151GluAla: 9.151 ± 0.113	0.248GluCys: 0.248 ± 0.014	2.892GluAsp: 2.892 ± 0.052	3.119GluGlu: 3.119 ± 0.064	1.719GluPhe: 1.719 ± 0.041	4.869GluGly: 4.869 ± 0.076	1.169GluHis: 1.169 ± 0.032	2.993GluIle: 2.993 ± 0.059	1.772GluLys: 1.772 ± 0.044	5.931GluLeu: 5.931 ± 0.08	1.286GluMet: 1.286 ± 0.033	1.274GluAsn: 1.274 ± 0.038	3.31GluPro: 3.31 ± 0.06	2.334GluGln: 2.334 ± 0.048	5.435GluArg: 5.435 ± 0.085	2.266GluSer: 2.266 ± 0.05	3.323GluThr: 3.323 ± 0.055	4.301GluVal: 4.301 ± 0.071	0.7GluTrp: 0.7 ± 0.027	0.928GluTyr: 0.928 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.671PheAla: 4.671 ± 0.074	0.329PheCys: 0.329 ± 0.018	2.575PheAsp: 2.575 ± 0.049	2.338PheGlu: 2.338 ± 0.049	1.231PhePhe: 1.231 ± 0.035	3.55PheGly: 3.55 ± 0.062	0.683PheHis: 0.683 ± 0.023	1.295PheIle: 1.295 ± 0.037	0.913PheLys: 0.913 ± 0.032	3.012PheLeu: 3.012 ± 0.059	0.694PheMet: 0.694 ± 0.025	1.018PheAsn: 1.018 ± 0.038	1.447PhePro: 1.447 ± 0.037	1.124PheGln: 1.124 ± 0.032	2.431PheArg: 2.431 ± 0.045	2.069PheSer: 2.069 ± 0.042	1.904PheThr: 1.904 ± 0.047	2.671PheVal: 2.671 ± 0.055	0.542PheTrp: 0.542 ± 0.026	0.862PheTyr: 0.862 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	11.8GlyAla: 11.8 ± 0.154	0.782GlyCys: 0.782 ± 0.029	4.624GlyAsp: 4.624 ± 0.068	5.583GlyGlu: 5.583 ± 0.083	3.592GlyPhe: 3.592 ± 0.058	8.503GlyGly: 8.503 ± 0.132	1.583GlyHis: 1.583 ± 0.043	2.689GlyIle: 2.689 ± 0.052	2.823GlyLys: 2.823 ± 0.058	9.472GlyLeu: 9.472 ± 0.111	1.981GlyMet: 1.981 ± 0.045	1.57GlyAsn: 1.57 ± 0.047	4.432GlyPro: 4.432 ± 0.064	3.382GlyGln: 3.382 ± 0.061	7.234GlyArg: 7.234 ± 0.095	4.558GlySer: 4.558 ± 0.062	3.304GlyThr: 3.304 ± 0.062	7.594GlyVal: 7.594 ± 0.095	1.619GlyTrp: 1.619 ± 0.042	2.244GlyTyr: 2.244 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.175HisAla: 2.175 ± 0.051	0.151HisCys: 0.151 ± 0.011	1.032HisAsp: 1.032 ± 0.029	1.064HisGlu: 1.064 ± 0.03	0.68HisPhe: 0.68 ± 0.023	1.672HisGly: 1.672 ± 0.043	0.478HisHis: 0.478 ± 0.026	0.711HisIle: 0.711 ± 0.026	0.433HisLys: 0.433 ± 0.018	1.813HisLeu: 1.813 ± 0.041	0.409HisMet: 0.409 ± 0.017	0.391HisAsn: 0.391 ± 0.017	1.269HisPro: 1.269 ± 0.032	0.605HisGln: 0.605 ± 0.022	1.346HisArg: 1.346 ± 0.039	0.733HisSer: 0.733 ± 0.025	0.739HisThr: 0.739 ± 0.023	1.35HisVal: 1.35 ± 0.035	0.286HisTrp: 0.286 ± 0.015	0.447HisTyr: 0.447 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.79IleAla: 5.79 ± 0.07	0.409IleCys: 0.409 ± 0.021	2.674IleAsp: 2.674 ± 0.047	2.852IleGlu: 2.852 ± 0.054	1.321IlePhe: 1.321 ± 0.034	3.976IleGly: 3.976 ± 0.067	0.668IleHis: 0.668 ± 0.024	1.394IleIle: 1.394 ± 0.038	1.014IleLys: 1.014 ± 0.034	3.643IleLeu: 3.643 ± 0.067	0.708IleMet: 0.708 ± 0.024	1.116IleAsn: 1.116 ± 0.031	1.891IlePro: 1.891 ± 0.044	1.193IleGln: 1.193 ± 0.031	2.888IleArg: 2.888 ± 0.049	2.292IleSer: 2.292 ± 0.05	2.26IleThr: 2.26 ± 0.047	3.152IleVal: 3.152 ± 0.062	0.569IleTrp: 0.569 ± 0.021	0.898IleTyr: 0.898 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	4.084LysAla: 4.084 ± 0.067	0.107LysCys: 0.107 ± 0.009	1.539LysAsp: 1.539 ± 0.04	1.198LysGlu: 1.198 ± 0.036	0.766LysPhe: 0.766 ± 0.026	2.496LysGly: 2.496 ± 0.051	0.467LysHis: 0.467 ± 0.019	1.338LysIle: 1.338 ± 0.035	0.919LysLys: 0.919 ± 0.034	3.056LysLeu: 3.056 ± 0.061	0.566LysMet: 0.566 ± 0.023	0.668LysAsn: 0.668 ± 0.026	2.079LysPro: 2.079 ± 0.048	0.857LysGln: 0.857 ± 0.029	2.16LysArg: 2.16 ± 0.051	1.398LysSer: 1.398 ± 0.04	1.75LysThr: 1.75 ± 0.044	2.331LysVal: 2.331 ± 0.053	0.296LysTrp: 0.296 ± 0.017	0.505LysTyr: 0.505 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.929LeuAla: 14.929 ± 0.16	0.769LeuCys: 0.769 ± 0.029	5.781LeuAsp: 5.781 ± 0.066	5.86LeuGlu: 5.86 ± 0.075	3.447LeuPhe: 3.447 ± 0.066	8.405LeuGly: 8.405 ± 0.088	1.721LeuHis: 1.721 ± 0.04	4.3LeuIle: 4.3 ± 0.062	3.517LeuLys: 3.517 ± 0.059	9.044LeuLeu: 9.044 ± 0.117	2.156LeuMet: 2.156 ± 0.045	2.652LeuAsn: 2.652 ± 0.049	5.277LeuPro: 5.277 ± 0.063	3.337LeuGln: 3.337 ± 0.057	7.263LeuArg: 7.263 ± 0.081	6.376LeuSer: 6.376 ± 0.13	5.778LeuThr: 5.778 ± 0.081	7.419LeuVal: 7.419 ± 0.096	1.206LeuTrp: 1.206 ± 0.036	1.927LeuTyr: 1.927 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.961MetAla: 2.961 ± 0.057	0.134MetCys: 0.134 ± 0.01	1.143MetAsp: 1.143 ± 0.03	1.015MetGlu: 1.015 ± 0.029	0.654MetPhe: 0.654 ± 0.022	1.77MetGly: 1.77 ± 0.039	0.359MetHis: 0.359 ± 0.018	0.984MetIle: 0.984 ± 0.031	0.78MetLys: 0.78 ± 0.028	2.005MetLeu: 2.005 ± 0.048	0.478MetMet: 0.478 ± 0.019	0.632MetAsn: 0.632 ± 0.026	1.289MetPro: 1.289 ± 0.034	0.644MetGln: 0.644 ± 0.023	1.689MetArg: 1.689 ± 0.043	1.628MetSer: 1.628 ± 0.039	1.467MetThr: 1.467 ± 0.033	1.391MetVal: 1.391 ± 0.036	0.203MetTrp: 0.203 ± 0.013	0.26MetTyr: 0.26 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.058AsnAla: 3.058 ± 0.05	0.19AsnCys: 0.19 ± 0.014	1.242AsnAsp: 1.242 ± 0.033	1.089AsnGlu: 1.089 ± 0.031	0.811AsnPhe: 0.811 ± 0.031	2.263AsnGly: 2.263 ± 0.053	0.424AsnHis: 0.424 ± 0.019	1.104AsnIle: 1.104 ± 0.032	0.526AsnLys: 0.526 ± 0.026	2.57AsnLeu: 2.57 ± 0.056	0.46AsnMet: 0.46 ± 0.021	0.667AsnAsn: 0.667 ± 0.029	1.748AsnPro: 1.748 ± 0.039	0.722AsnGln: 0.722 ± 0.022	1.659AsnArg: 1.659 ± 0.035	1.086AsnSer: 1.086 ± 0.034	1.186AsnThr: 1.186 ± 0.045	1.832AsnVal: 1.832 ± 0.044	0.376AsnTrp: 0.376 ± 0.019	0.652AsnTyr: 0.652 ± 0.027	0.0AsnXaa: 0.0 ± 0.0
Pro	7.967ProAla: 7.967 ± 0.105	0.298ProCys: 0.298 ± 0.016	3.671ProAsp: 3.671 ± 0.054	4.047ProGlu: 4.047 ± 0.061	2.016ProPhe: 2.016 ± 0.037	5.125ProGly: 5.125 ± 0.062	1.018ProHis: 1.018 ± 0.033	2.175ProIle: 2.175 ± 0.048	1.742ProLys: 1.742 ± 0.048	4.995ProLeu: 4.995 ± 0.071	1.12ProMet: 1.12 ± 0.029	1.447ProAsn: 1.447 ± 0.035	3.417ProPro: 3.417 ± 0.093	2.162ProGln: 2.162 ± 0.043	3.438ProArg: 3.438 ± 0.053	2.908ProSer: 2.908 ± 0.053	2.791ProThr: 2.791 ± 0.057	4.353ProVal: 4.353 ± 0.062	0.773ProTrp: 0.773 ± 0.029	1.082ProTyr: 1.082 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	5.525GlnAla: 5.525 ± 0.077	0.168GlnCys: 0.168 ± 0.012	1.578GlnAsp: 1.578 ± 0.035	1.537GlnGlu: 1.537 ± 0.046	1.004GlnPhe: 1.004 ± 0.031	2.961GlnGly: 2.961 ± 0.052	0.591GlnHis: 0.591 ± 0.022	1.732GlnIle: 1.732 ± 0.045	0.913GlnLys: 0.913 ± 0.03	3.435GlnLeu: 3.435 ± 0.066	0.845GlnMet: 0.845 ± 0.024	0.8GlnAsn: 0.8 ± 0.024	2.216GlnPro: 2.216 ± 0.046	1.304GlnGln: 1.304 ± 0.039	2.704GlnArg: 2.704 ± 0.054	1.672GlnSer: 1.672 ± 0.039	1.871GlnThr: 1.871 ± 0.042	2.989GlnVal: 2.989 ± 0.061	0.398GlnTrp: 0.398 ± 0.019	0.575GlnTyr: 0.575 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	9.473ArgAla: 9.473 ± 0.098	0.468ArgCys: 0.468 ± 0.022	4.068ArgAsp: 4.068 ± 0.075	4.606ArgGlu: 4.606 ± 0.078	3.112ArgPhe: 3.112 ± 0.053	5.605ArgGly: 5.605 ± 0.085	1.396ArgHis: 1.396 ± 0.038	3.56ArgIle: 3.56 ± 0.057	2.188ArgLys: 2.188 ± 0.046	9.101ArgLeu: 9.101 ± 0.11	1.951ArgMet: 1.951 ± 0.042	1.782ArgAsn: 1.782 ± 0.042	4.384ArgPro: 4.384 ± 0.065	2.815ArgGln: 2.815 ± 0.052	6.855ArgArg: 6.855 ± 0.106	3.665ArgSer: 3.665 ± 0.06	3.982ArgThr: 3.982 ± 0.063	5.231ArgVal: 5.231 ± 0.079	1.275ArgTrp: 1.275 ± 0.035	1.768ArgTyr: 1.768 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	6.611SerAla: 6.611 ± 0.093	0.367SerCys: 0.367 ± 0.019	2.823SerAsp: 2.823 ± 0.052	2.811SerGlu: 2.811 ± 0.043	2.032SerPhe: 2.032 ± 0.043	5.434SerGly: 5.434 ± 0.081	0.92SerHis: 0.92 ± 0.028	2.018SerIle: 2.018 ± 0.046	1.407SerLys: 1.407 ± 0.036	5.102SerLeu: 5.102 ± 0.073	1.093SerMet: 1.093 ± 0.028	1.276SerAsn: 1.276 ± 0.038	3.045SerPro: 3.045 ± 0.056	1.703SerGln: 1.703 ± 0.037	3.859SerArg: 3.859 ± 0.058	2.63SerSer: 2.63 ± 0.068	2.615SerThr: 2.615 ± 0.075	3.589SerVal: 3.589 ± 0.066	0.78SerTrp: 0.78 ± 0.025	1.215SerTyr: 1.215 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	6.62ThrAla: 6.62 ± 0.086	0.365ThrCys: 0.365 ± 0.019	2.63ThrAsp: 2.63 ± 0.05	2.441ThrGlu: 2.441 ± 0.048	1.91ThrPhe: 1.91 ± 0.039	5.125ThrGly: 5.125 ± 0.092	0.892ThrHis: 0.892 ± 0.032	1.975ThrIle: 1.975 ± 0.049	1.124ThrLys: 1.124 ± 0.036	5.245ThrLeu: 5.245 ± 0.065	0.872ThrMet: 0.872 ± 0.03	1.186ThrAsn: 1.186 ± 0.042	3.858ThrPro: 3.858 ± 0.058	1.598ThrGln: 1.598 ± 0.062	3.387ThrArg: 3.387 ± 0.063	2.631ThrSer: 2.631 ± 0.052	2.739ThrThr: 2.739 ± 0.09	4.094ThrVal: 4.094 ± 0.06	0.707ThrTrp: 0.707 ± 0.027	1.21ThrTyr: 1.21 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	9.576ValAla: 9.576 ± 0.107	0.568ValCys: 0.568 ± 0.022	4.294ValAsp: 4.294 ± 0.056	4.894ValGlu: 4.894 ± 0.07	2.639ValPhe: 2.639 ± 0.054	6.317ValGly: 6.317 ± 0.079	1.257ValHis: 1.257 ± 0.031	3.434ValIle: 3.434 ± 0.057	2.064ValLys: 2.064 ± 0.052	7.827ValLeu: 7.827 ± 0.1	1.609ValMet: 1.609 ± 0.03	1.997ValAsn: 1.997 ± 0.047	3.093ValPro: 3.093 ± 0.057	2.552ValGln: 2.552 ± 0.047	6.021ValArg: 6.021 ± 0.064	4.266ValSer: 4.266 ± 0.06	4.573ValThr: 4.573 ± 0.068	6.403ValVal: 6.403 ± 0.08	1.025ValTrp: 1.025 ± 0.025	1.386ValTyr: 1.386 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.528TrpAla: 1.528 ± 0.039	0.113TrpCys: 0.113 ± 0.01	0.692TrpAsp: 0.692 ± 0.027	0.607TrpGlu: 0.607 ± 0.024	0.523TrpPhe: 0.523 ± 0.022	1.08TrpGly: 1.08 ± 0.035	0.221TrpHis: 0.221 ± 0.013	0.64TrpIle: 0.64 ± 0.023	0.427TrpLys: 0.427 ± 0.023	1.604TrpLeu: 1.604 ± 0.034	0.359TrpMet: 0.359 ± 0.018	0.453TrpAsn: 0.453 ± 0.02	0.793TrpPro: 0.793 ± 0.028	0.407TrpGln: 0.407 ± 0.019	1.662TrpArg: 1.662 ± 0.044	0.91TrpSer: 0.91 ± 0.028	0.978TrpThr: 0.978 ± 0.032	0.857TrpVal: 0.857 ± 0.027	0.263TrpTrp: 0.263 ± 0.016	0.263TrpTyr: 0.263 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.547TyrAla: 2.547 ± 0.052	0.165TyrCys: 0.165 ± 0.013	1.385TyrAsp: 1.385 ± 0.039	1.284TyrGlu: 1.284 ± 0.031	0.767TyrPhe: 0.767 ± 0.026	2.185TyrGly: 2.185 ± 0.05	0.396TyrHis: 0.396 ± 0.019	0.663TyrIle: 0.663 ± 0.027	0.54TyrLys: 0.54 ± 0.024	2.017TyrLeu: 2.017 ± 0.045	0.372TyrMet: 0.372 ± 0.018	0.561TyrAsn: 0.561 ± 0.021	1.037TyrPro: 1.037 ± 0.029	0.717TyrGln: 0.717 ± 0.027	1.794TyrArg: 1.794 ± 0.041	1.121TyrSer: 1.121 ± 0.033	0.963TyrThr: 0.963 ± 0.029	1.687TyrVal: 1.687 ± 0.04	0.313TyrTrp: 0.313 ± 0.015	0.521TyrTyr: 0.521 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3698 proteins (1169876 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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