Amino acid dipepetide frequency for Muricauda lutaonensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.041AlaAla: 5.041 ± 0.087
0.618AlaCys: 0.618 ± 0.026
4.048AlaAsp: 4.048 ± 0.155
4.661AlaGlu: 4.661 ± 0.088
3.525AlaPhe: 3.525 ± 0.069
4.439AlaGly: 4.439 ± 0.091
1.435AlaHis: 1.435 ± 0.043
5.392AlaIle: 5.392 ± 0.08
4.962AlaLys: 4.962 ± 0.093
6.98AlaLeu: 6.98 ± 0.107
1.786AlaMet: 1.786 ± 0.047
3.467AlaAsn: 3.467 ± 0.075
2.324AlaPro: 2.324 ± 0.062
2.771AlaGln: 2.771 ± 0.055
2.48AlaArg: 2.48 ± 0.056
4.096AlaSer: 4.096 ± 0.067
3.832AlaThr: 3.832 ± 0.085
4.604AlaVal: 4.604 ± 0.068
0.652AlaTrp: 0.652 ± 0.028
2.614AlaTyr: 2.614 ± 0.053
0.0AlaXaa: 0.0 ± 0.0
Cys
0.497CysAla: 0.497 ± 0.023
0.104CysCys: 0.104 ± 0.01
0.417CysAsp: 0.417 ± 0.023
0.464CysGlu: 0.464 ± 0.022
0.409CysPhe: 0.409 ± 0.023
0.606CysGly: 0.606 ± 0.029
0.218CysHis: 0.218 ± 0.016
0.491CysIle: 0.491 ± 0.022
0.406CysLys: 0.406 ± 0.02
0.663CysLeu: 0.663 ± 0.027
0.173CysMet: 0.173 ± 0.013
0.376CysAsn: 0.376 ± 0.025
0.335CysPro: 0.335 ± 0.026
0.249CysGln: 0.249 ± 0.018
0.248CysArg: 0.248 ± 0.016
0.527CysSer: 0.527 ± 0.027
0.483CysThr: 0.483 ± 0.034
0.423CysVal: 0.423 ± 0.023
0.06CysTrp: 0.06 ± 0.008
0.315CysTyr: 0.315 ± 0.019
0.0CysXaa: 0.0 ± 0.0
Asp
3.997AspAla: 3.997 ± 0.112
0.433AspCys: 0.433 ± 0.024
3.472AspAsp: 3.472 ± 0.099
4.096AspGlu: 4.096 ± 0.076
3.834AspPhe: 3.834 ± 0.079
4.59AspGly: 4.59 ± 0.206
1.105AspHis: 1.105 ± 0.032
4.163AspIle: 4.163 ± 0.08
3.621AspLys: 3.621 ± 0.071
5.231AspLeu: 5.231 ± 0.078
1.233AspMet: 1.233 ± 0.036
2.947AspAsn: 2.947 ± 0.116
2.202AspPro: 2.202 ± 0.095
1.691AspGln: 1.691 ± 0.043
2.367AspArg: 2.367 ± 0.051
3.197AspSer: 3.197 ± 0.068
2.965AspThr: 2.965 ± 0.078
3.686AspVal: 3.686 ± 0.078
0.836AspTrp: 0.836 ± 0.034
2.723AspTyr: 2.723 ± 0.065
0.0AspXaa: 0.0 ± 0.0
Glu
5.004GluAla: 5.004 ± 0.091
0.352GluCys: 0.352 ± 0.022
3.548GluAsp: 3.548 ± 0.069
5.494GluGlu: 5.494 ± 0.098
2.774GluPhe: 2.774 ± 0.06
4.228GluGly: 4.228 ± 0.078
1.365GluHis: 1.365 ± 0.038
4.983GluIle: 4.983 ± 0.078
6.098GluLys: 6.098 ± 0.12
6.551GluLeu: 6.551 ± 0.088
1.759GluMet: 1.759 ± 0.044
4.196GluAsn: 4.196 ± 0.071
1.941GluPro: 1.941 ± 0.045
2.391GluGln: 2.391 ± 0.06
3.249GluArg: 3.249 ± 0.069
3.055GluSer: 3.055 ± 0.063
3.641GluThr: 3.641 ± 0.064
4.851GluVal: 4.851 ± 0.086
0.721GluTrp: 0.721 ± 0.028
2.392GluTyr: 2.392 ± 0.048
0.0GluXaa: 0.0 ± 0.0
Phe
3.252PheAla: 3.252 ± 0.066
0.448PheCys: 0.448 ± 0.023
3.575PheAsp: 3.575 ± 0.064
3.726PheGlu: 3.726 ± 0.062
2.919PhePhe: 2.919 ± 0.08
3.875PheGly: 3.875 ± 0.075
0.845PheHis: 0.845 ± 0.034
3.145PheIle: 3.145 ± 0.06
3.241PheLys: 3.241 ± 0.077
5.006PheLeu: 5.006 ± 0.106
1.176PheMet: 1.176 ± 0.037
2.676PheAsn: 2.676 ± 0.061
1.766PhePro: 1.766 ± 0.045
1.524PheGln: 1.524 ± 0.037
1.875PheArg: 1.875 ± 0.044
3.518PheSer: 3.518 ± 0.072
2.799PheThr: 2.799 ± 0.07
3.358PheVal: 3.358 ± 0.062
0.625PheTrp: 0.625 ± 0.027
2.085PheTyr: 2.085 ± 0.049
0.0PheXaa: 0.0 ± 0.0
Gly
4.695GlyAla: 4.695 ± 0.087
0.677GlyCys: 0.677 ± 0.051
3.967GlyAsp: 3.967 ± 0.11
3.998GlyGlu: 3.998 ± 0.065
3.903GlyPhe: 3.903 ± 0.067
5.181GlyGly: 5.181 ± 0.16
1.528GlyHis: 1.528 ± 0.042
5.345GlyIle: 5.345 ± 0.083
4.975GlyLys: 4.975 ± 0.081
6.447GlyLeu: 6.447 ± 0.098
1.766GlyMet: 1.766 ± 0.045
3.845GlyAsn: 3.845 ± 0.098
1.767GlyPro: 1.767 ± 0.049
2.37GlyGln: 2.37 ± 0.051
2.707GlyArg: 2.707 ± 0.065
4.161GlySer: 4.161 ± 0.094
4.221GlyThr: 4.221 ± 0.131
4.663GlyVal: 4.663 ± 0.085
0.864GlyTrp: 0.864 ± 0.033
2.812GlyTyr: 2.812 ± 0.066
0.0GlyXaa: 0.0 ± 0.0
His
1.088HisAla: 1.088 ± 0.035
0.224HisCys: 0.224 ± 0.017
0.955HisAsp: 0.955 ± 0.029
1.203HisGlu: 1.203 ± 0.039
1.175HisPhe: 1.175 ± 0.034
1.278HisGly: 1.278 ± 0.039
0.568HisHis: 0.568 ± 0.027
1.484HisIle: 1.484 ± 0.042
1.184HisLys: 1.184 ± 0.042
2.018HisLeu: 2.018 ± 0.054
0.386HisMet: 0.386 ± 0.022
0.851HisAsn: 0.851 ± 0.035
1.043HisPro: 1.043 ± 0.034
0.815HisGln: 0.815 ± 0.032
0.898HisArg: 0.898 ± 0.032
1.059HisSer: 1.059 ± 0.035
1.046HisThr: 1.046 ± 0.032
1.088HisVal: 1.088 ± 0.039
0.28HisTrp: 0.28 ± 0.017
0.893HisTyr: 0.893 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
5.494IleAla: 5.494 ± 0.084
0.538IleCys: 0.538 ± 0.021
4.711IleAsp: 4.711 ± 0.073
5.027IleGlu: 5.027 ± 0.076
3.326IlePhe: 3.326 ± 0.067
4.788IleGly: 4.788 ± 0.086
1.172IleHis: 1.172 ± 0.035
4.56IleIle: 4.56 ± 0.088
4.641IleLys: 4.641 ± 0.077
6.118IleLeu: 6.118 ± 0.1
1.273IleMet: 1.273 ± 0.043
3.561IleAsn: 3.561 ± 0.072
2.946IlePro: 2.946 ± 0.064
2.002IleGln: 2.002 ± 0.046
2.795IleArg: 2.795 ± 0.06
4.684IleSer: 4.684 ± 0.092
4.062IleThr: 4.062 ± 0.111
4.363IleVal: 4.363 ± 0.074
0.64IleTrp: 0.64 ± 0.028
2.4IleTyr: 2.4 ± 0.058
0.0IleXaa: 0.0 ± 0.0
Lys
5.05LysAla: 5.05 ± 0.097
0.305LysCys: 0.305 ± 0.019
3.931LysAsp: 3.931 ± 0.072
5.941LysGlu: 5.941 ± 0.104
2.386LysPhe: 2.386 ± 0.053
4.659LysGly: 4.659 ± 0.082
1.295LysHis: 1.295 ± 0.048
4.991LysIle: 4.991 ± 0.085
6.93LysLys: 6.93 ± 0.119
5.955LysLeu: 5.955 ± 0.102
1.899LysMet: 1.899 ± 0.047
4.374LysAsn: 4.374 ± 0.084
2.418LysPro: 2.418 ± 0.056
2.48LysGln: 2.48 ± 0.055
3.258LysArg: 3.258 ± 0.066
3.874LysSer: 3.874 ± 0.071
4.07LysThr: 4.07 ± 0.075
4.765LysVal: 4.765 ± 0.089
0.82LysTrp: 0.82 ± 0.034
2.584LysTyr: 2.584 ± 0.059
0.0LysXaa: 0.0 ± 0.0
Leu
6.863LeuAla: 6.863 ± 0.112
0.705LeuCys: 0.705 ± 0.028
5.456LeuAsp: 5.456 ± 0.077
6.379LeuGlu: 6.379 ± 0.092
4.9LeuPhe: 4.9 ± 0.101
6.548LeuGly: 6.548 ± 0.1
1.751LeuHis: 1.751 ± 0.053
5.702LeuIle: 5.702 ± 0.1
7.161LeuLys: 7.161 ± 0.111
9.516LeuLeu: 9.516 ± 0.137
2.294LeuMet: 2.294 ± 0.054
4.84LeuAsn: 4.84 ± 0.065
3.904LeuPro: 3.904 ± 0.072
3.556LeuGln: 3.556 ± 0.076
3.867LeuArg: 3.867 ± 0.061
5.98LeuSer: 5.98 ± 0.078
4.947LeuThr: 4.947 ± 0.08
6.432LeuVal: 6.432 ± 0.097
0.942LeuTrp: 0.942 ± 0.033
3.172LeuTyr: 3.172 ± 0.072
0.0LeuXaa: 0.0 ± 0.0
Met
2.21MetAla: 2.21 ± 0.054
0.129MetCys: 0.129 ± 0.012
1.238MetAsp: 1.238 ± 0.039
1.544MetGlu: 1.544 ± 0.044
0.819MetPhe: 0.819 ± 0.032
1.872MetGly: 1.872 ± 0.05
0.441MetHis: 0.441 ± 0.022
1.194MetIle: 1.194 ± 0.04
1.989MetLys: 1.989 ± 0.051
2.114MetLeu: 2.114 ± 0.056
0.597MetMet: 0.597 ± 0.032
1.13MetAsn: 1.13 ± 0.038
1.04MetPro: 1.04 ± 0.032
0.888MetGln: 0.888 ± 0.033
1.079MetArg: 1.079 ± 0.034
1.178MetSer: 1.178 ± 0.035
1.158MetThr: 1.158 ± 0.036
1.798MetVal: 1.798 ± 0.052
0.168MetTrp: 0.168 ± 0.013
0.658MetTyr: 0.658 ± 0.026
0.0MetXaa: 0.0 ± 0.0
Asn
3.6AsnAla: 3.6 ± 0.075
0.416AsnCys: 0.416 ± 0.028
3.224AsnAsp: 3.224 ± 0.105
3.277AsnGlu: 3.277 ± 0.093
2.732AsnPhe: 2.732 ± 0.069
4.129AsnGly: 4.129 ± 0.125
0.975AsnHis: 0.975 ± 0.031
3.864AsnIle: 3.864 ± 0.073
3.112AsnLys: 3.112 ± 0.072
4.831AsnLeu: 4.831 ± 0.082
1.176AsnMet: 1.176 ± 0.036
2.884AsnAsn: 2.884 ± 0.092
2.745AsnPro: 2.745 ± 0.064
1.917AsnGln: 1.917 ± 0.048
2.384AsnArg: 2.384 ± 0.052
2.864AsnSer: 2.864 ± 0.068
3.08AsnThr: 3.08 ± 0.083
3.331AsnVal: 3.331 ± 0.066
0.687AsnTrp: 0.687 ± 0.029
2.095AsnTyr: 2.095 ± 0.049
0.0AsnXaa: 0.0 ± 0.0
Pro
2.111ProAla: 2.111 ± 0.059
0.229ProCys: 0.229 ± 0.016
2.517ProAsp: 2.517 ± 0.084
3.157ProGlu: 3.157 ± 0.056
2.011ProPhe: 2.011 ± 0.053
2.228ProGly: 2.228 ± 0.065
0.737ProHis: 0.737 ± 0.029
2.715ProIle: 2.715 ± 0.053
2.809ProLys: 2.809 ± 0.061
3.404ProLeu: 3.404 ± 0.056
0.897ProMet: 0.897 ± 0.038
2.191ProAsn: 2.191 ± 0.058
1.205ProPro: 1.205 ± 0.047
1.277ProGln: 1.277 ± 0.038
1.197ProArg: 1.197 ± 0.042
2.187ProSer: 2.187 ± 0.062
2.168ProThr: 2.168 ± 0.079
2.558ProVal: 2.558 ± 0.057
0.421ProTrp: 0.421 ± 0.023
1.458ProTyr: 1.458 ± 0.044
0.0ProXaa: 0.0 ± 0.0
Gln
2.229GlnAla: 2.229 ± 0.045
0.181GlnCys: 0.181 ± 0.014
1.69GlnAsp: 1.69 ± 0.052
2.487GlnGlu: 2.487 ± 0.054
1.635GlnPhe: 1.635 ± 0.045
2.134GlnGly: 2.134 ± 0.055
0.713GlnHis: 0.713 ± 0.028
2.376GlnIle: 2.376 ± 0.055
2.891GlnLys: 2.891 ± 0.058
3.623GlnLeu: 3.623 ± 0.062
0.916GlnMet: 0.916 ± 0.032
2.01GlnAsn: 2.01 ± 0.049
1.156GlnPro: 1.156 ± 0.032
1.534GlnGln: 1.534 ± 0.049
1.676GlnArg: 1.676 ± 0.05
1.747GlnSer: 1.747 ± 0.041
1.802GlnThr: 1.802 ± 0.043
2.186GlnVal: 2.186 ± 0.048
0.417GlnTrp: 0.417 ± 0.02
1.351GlnTyr: 1.351 ± 0.035
0.0GlnXaa: 0.0 ± 0.0
Arg
2.616ArgAla: 2.616 ± 0.055
0.236ArgCys: 0.236 ± 0.015
2.02ArgAsp: 2.02 ± 0.049
2.638ArgGlu: 2.638 ± 0.056
2.413ArgPhe: 2.413 ± 0.054
2.413ArgGly: 2.413 ± 0.055
0.866ArgHis: 0.866 ± 0.026
3.095ArgIle: 3.095 ± 0.055
3.224ArgLys: 3.224 ± 0.073
4.134ArgLeu: 4.134 ± 0.079
1.012ArgMet: 1.012 ± 0.037
2.21ArgAsn: 2.21 ± 0.049
1.665ArgPro: 1.665 ± 0.044
1.521ArgGln: 1.521 ± 0.046
1.773ArgArg: 1.773 ± 0.051
2.179ArgSer: 2.179 ± 0.06
2.122ArgThr: 2.122 ± 0.051
2.393ArgVal: 2.393 ± 0.055
0.484ArgTrp: 0.484 ± 0.023
1.889ArgTyr: 1.889 ± 0.051
0.0ArgXaa: 0.0 ± 0.0
Ser
3.762SerAla: 3.762 ± 0.066
0.56SerCys: 0.56 ± 0.032
3.205SerAsp: 3.205 ± 0.065
3.832SerGlu: 3.832 ± 0.066
3.29SerPhe: 3.29 ± 0.063
4.695SerGly: 4.695 ± 0.113
0.96SerHis: 0.96 ± 0.039
4.223SerIle: 4.223 ± 0.081
4.085SerLys: 4.085 ± 0.071
5.572SerLeu: 5.572 ± 0.084
1.279SerMet: 1.279 ± 0.033
3.008SerAsn: 3.008 ± 0.071
2.107SerPro: 2.107 ± 0.054
1.901SerGln: 1.901 ± 0.045
2.208SerArg: 2.208 ± 0.051
3.391SerSer: 3.391 ± 0.068
3.208SerThr: 3.208 ± 0.078
3.757SerVal: 3.757 ± 0.069
0.676SerTrp: 0.676 ± 0.029
2.263SerTyr: 2.263 ± 0.053
0.0SerXaa: 0.0 ± 0.0
Thr
3.936ThrAla: 3.936 ± 0.085
0.337ThrCys: 0.337 ± 0.026
3.398ThrAsp: 3.398 ± 0.107
3.291ThrGlu: 3.291 ± 0.057
3.004ThrPhe: 3.004 ± 0.075
4.122ThrGly: 4.122 ± 0.091
1.045ThrHis: 1.045 ± 0.03
4.24ThrIle: 4.24 ± 0.092
3.292ThrLys: 3.292 ± 0.066
5.365ThrLeu: 5.365 ± 0.08
1.052ThrMet: 1.052 ± 0.034
2.748ThrAsn: 2.748 ± 0.125
2.438ThrPro: 2.438 ± 0.064
1.727ThrGln: 1.727 ± 0.045
1.736ThrArg: 1.736 ± 0.046
3.27ThrSer: 3.27 ± 0.081
3.101ThrThr: 3.101 ± 0.083
4.189ThrVal: 4.189 ± 0.132
0.579ThrTrp: 0.579 ± 0.031
2.217ThrTyr: 2.217 ± 0.054
0.0ThrXaa: 0.0 ± 0.0
Val
4.947ValAla: 4.947 ± 0.082
0.544ValCys: 0.544 ± 0.027
4.095ValAsp: 4.095 ± 0.119
4.363ValGlu: 4.363 ± 0.071
3.556ValPhe: 3.556 ± 0.071
4.498ValGly: 4.498 ± 0.079
1.294ValHis: 1.294 ± 0.038
4.252ValIle: 4.252 ± 0.07
4.189ValLys: 4.189 ± 0.088
6.61ValLeu: 6.61 ± 0.1
1.498ValMet: 1.498 ± 0.044
3.313ValAsn: 3.313 ± 0.072
2.686ValPro: 2.686 ± 0.058
2.072ValGln: 2.072 ± 0.048
2.595ValArg: 2.595 ± 0.065
4.218ValSer: 4.218 ± 0.07
3.763ValThr: 3.763 ± 0.132
5.026ValVal: 5.026 ± 0.084
0.715ValTrp: 0.715 ± 0.028
2.393ValTyr: 2.393 ± 0.053
0.0ValXaa: 0.0 ± 0.0
Trp
0.758TrpAla: 0.758 ± 0.026
0.097TrpCys: 0.097 ± 0.01
0.621TrpAsp: 0.621 ± 0.033
0.681TrpGlu: 0.681 ± 0.027
0.578TrpPhe: 0.578 ± 0.024
0.757TrpGly: 0.757 ± 0.036
0.307TrpHis: 0.307 ± 0.02
0.66TrpIle: 0.66 ± 0.03
0.779TrpLys: 0.779 ± 0.03
1.09TrpLeu: 1.09 ± 0.033
0.339TrpMet: 0.339 ± 0.019
0.67TrpAsn: 0.67 ± 0.028
0.354TrpPro: 0.354 ± 0.019
0.535TrpGln: 0.535 ± 0.025
0.498TrpArg: 0.498 ± 0.023
0.622TrpSer: 0.622 ± 0.028
0.524TrpThr: 0.524 ± 0.026
0.768TrpVal: 0.768 ± 0.028
0.167TrpTrp: 0.167 ± 0.015
0.445TrpTyr: 0.445 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.579TyrAla: 2.579 ± 0.054
0.33TyrCys: 0.33 ± 0.02
2.302TyrAsp: 2.302 ± 0.06
2.334TyrGlu: 2.334 ± 0.06
2.242TyrPhe: 2.242 ± 0.05
2.851TyrGly: 2.851 ± 0.062
0.918TyrHis: 0.918 ± 0.032
2.227TyrIle: 2.227 ± 0.053
2.393TyrLys: 2.393 ± 0.051
3.687TyrLeu: 3.687 ± 0.07
0.733TyrMet: 0.733 ± 0.023
2.029TyrAsn: 2.029 ± 0.046
1.436TyrPro: 1.436 ± 0.047
1.534TyrGln: 1.534 ± 0.047
2.01TyrArg: 2.01 ± 0.053
2.174TyrSer: 2.174 ± 0.047
2.095TyrThr: 2.095 ± 0.065
2.389TyrVal: 2.389 ± 0.048
0.494TyrTrp: 0.494 ± 0.027
1.565TyrTyr: 1.565 ± 0.046
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2882 proteins (971754 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski