Amino acid dipepetide frequency for Spider associated circular virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.918AlaAla: 4.918 ± 1.32
1.639AlaCys: 1.639 ± 1.231
6.557AlaAsp: 6.557 ± 2.551
3.279AlaGlu: 3.279 ± 0.089
4.918AlaPhe: 4.918 ± 1.32
4.918AlaGly: 4.918 ± 3.425
0.0AlaHis: 0.0 ± 0.0
6.557AlaIle: 6.557 ± 0.179
3.279AlaLys: 3.279 ± 0.089
3.279AlaLeu: 3.279 ± 2.462
1.639AlaMet: 1.639 ± 1.142
3.279AlaAsn: 3.279 ± 2.283
4.918AlaPro: 4.918 ± 3.425
1.639AlaGln: 1.639 ± 1.231
4.918AlaArg: 4.918 ± 1.32
4.918AlaSer: 4.918 ± 1.32
1.639AlaThr: 1.639 ± 1.142
1.639AlaVal: 1.639 ± 1.231
3.279AlaTrp: 3.279 ± 2.462
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
3.279CysAsp: 3.279 ± 2.462
0.0CysGlu: 0.0 ± 0.0
3.279CysPhe: 3.279 ± 0.089
1.639CysGly: 1.639 ± 1.231
0.0CysHis: 0.0 ± 0.0
3.279CysIle: 3.279 ± 0.089
0.0CysLys: 0.0 ± 0.0
1.639CysLeu: 1.639 ± 1.231
0.0CysMet: 0.0 ± 0.0
1.639CysAsn: 1.639 ± 1.231
1.639CysPro: 1.639 ± 1.142
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.639CysSer: 1.639 ± 1.142
0.0CysThr: 0.0 ± 0.0
1.639CysVal: 1.639 ± 1.231
1.639CysTrp: 1.639 ± 1.142
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.557AspAla: 6.557 ± 4.924
0.0AspCys: 0.0 ± 0.0
6.557AspAsp: 6.557 ± 0.179
1.639AspGlu: 1.639 ± 1.142
1.639AspPhe: 1.639 ± 1.231
8.197AspGly: 8.197 ± 6.155
0.0AspHis: 0.0 ± 0.0
4.918AspIle: 4.918 ± 1.32
1.639AspLys: 1.639 ± 1.142
4.918AspLeu: 4.918 ± 3.425
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
4.918AspPro: 4.918 ± 1.32
1.639AspGln: 1.639 ± 1.231
3.279AspArg: 3.279 ± 2.462
0.0AspSer: 0.0 ± 0.0
4.918AspThr: 4.918 ± 3.425
8.197AspVal: 8.197 ± 1.41
4.918AspTrp: 4.918 ± 1.32
3.279AspTyr: 3.279 ± 0.089
0.0AspXaa: 0.0 ± 0.0
Glu
1.639GluAla: 1.639 ± 1.142
1.639GluCys: 1.639 ± 1.231
3.279GluAsp: 3.279 ± 0.089
1.639GluGlu: 1.639 ± 1.231
0.0GluPhe: 0.0 ± 0.0
0.0GluGly: 0.0 ± 0.0
3.279GluHis: 3.279 ± 2.462
4.918GluIle: 4.918 ± 3.693
3.279GluLys: 3.279 ± 2.283
4.918GluLeu: 4.918 ± 3.693
1.639GluMet: 1.639 ± 1.142
1.639GluAsn: 1.639 ± 1.231
4.918GluPro: 4.918 ± 3.693
3.279GluGln: 3.279 ± 2.462
4.918GluArg: 4.918 ± 1.052
1.639GluSer: 1.639 ± 1.231
1.639GluThr: 1.639 ± 1.142
1.639GluVal: 1.639 ± 1.142
1.639GluTrp: 1.639 ± 1.231
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.639PheAla: 1.639 ± 1.142
3.279PheCys: 3.279 ± 2.283
3.279PheAsp: 3.279 ± 2.462
0.0PheGlu: 0.0 ± 0.0
3.279PhePhe: 3.279 ± 0.089
3.279PheGly: 3.279 ± 0.089
0.0PheHis: 0.0 ± 0.0
1.639PheIle: 1.639 ± 1.231
3.279PheLys: 3.279 ± 0.089
0.0PheLeu: 0.0 ± 0.0
1.639PheMet: 1.639 ± 1.142
1.639PheAsn: 1.639 ± 1.142
1.639PhePro: 1.639 ± 1.231
1.639PheGln: 1.639 ± 1.231
8.197PheArg: 8.197 ± 3.782
4.918PheSer: 4.918 ± 1.052
1.639PheThr: 1.639 ± 1.142
6.557PheVal: 6.557 ± 4.924
3.279PheTrp: 3.279 ± 0.089
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.557GlyAla: 6.557 ± 0.179
0.0GlyCys: 0.0 ± 0.0
6.557GlyAsp: 6.557 ± 0.179
4.918GlyGlu: 4.918 ± 1.052
4.918GlyPhe: 4.918 ± 1.052
19.672GlyGly: 19.672 ± 0.537
0.0GlyHis: 0.0 ± 0.0
6.557GlyIle: 6.557 ± 2.551
1.639GlyLys: 1.639 ± 1.231
3.279GlyLeu: 3.279 ± 2.462
3.279GlyMet: 3.279 ± 2.283
1.639GlyAsn: 1.639 ± 1.142
3.279GlyPro: 3.279 ± 2.283
1.639GlyGln: 1.639 ± 1.231
8.197GlyArg: 8.197 ± 3.782
4.918GlySer: 4.918 ± 1.32
8.197GlyThr: 8.197 ± 3.335
8.197GlyVal: 8.197 ± 3.335
0.0GlyTrp: 0.0 ± 0.0
1.639GlyTyr: 1.639 ± 1.231
0.0GlyXaa: 0.0 ± 0.0
His
1.639HisAla: 1.639 ± 1.231
1.639HisCys: 1.639 ± 1.231
0.0HisAsp: 0.0 ± 0.0
1.639HisGlu: 1.639 ± 1.142
1.639HisPhe: 1.639 ± 1.231
1.639HisGly: 1.639 ± 1.231
1.639HisHis: 1.639 ± 1.231
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
4.918HisLeu: 4.918 ± 3.693
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.639HisPro: 1.639 ± 1.231
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
3.279IleAsp: 3.279 ± 2.283
1.639IleGlu: 1.639 ± 1.231
8.197IlePhe: 8.197 ± 1.41
1.639IleGly: 1.639 ± 1.142
3.279IleHis: 3.279 ± 2.462
1.639IleIle: 1.639 ± 1.142
3.279IleLys: 3.279 ± 2.462
3.279IleLeu: 3.279 ± 2.283
1.639IleMet: 1.639 ± 0.834
1.639IleAsn: 1.639 ± 1.142
0.0IlePro: 0.0 ± 0.0
1.639IleGln: 1.639 ± 1.142
6.557IleArg: 6.557 ± 0.179
0.0IleSer: 0.0 ± 0.0
4.918IleThr: 4.918 ± 1.32
3.279IleVal: 3.279 ± 2.462
3.279IleTrp: 3.279 ± 0.089
1.639IleTyr: 1.639 ± 1.142
0.0IleXaa: 0.0 ± 0.0
Lys
6.557LysAla: 6.557 ± 0.179
3.279LysCys: 3.279 ± 2.283
4.918LysAsp: 4.918 ± 1.32
3.279LysGlu: 3.279 ± 2.462
3.279LysPhe: 3.279 ± 2.462
1.639LysGly: 1.639 ± 1.142
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
6.557LysLys: 6.557 ± 2.194
0.0LysLeu: 0.0 ± 0.0
0.0LysMet: 0.0 ± 0.802
1.639LysAsn: 1.639 ± 1.142
3.279LysPro: 3.279 ± 2.462
0.0LysGln: 0.0 ± 0.0
8.197LysArg: 8.197 ± 3.335
6.557LysSer: 6.557 ± 4.566
1.639LysThr: 1.639 ± 1.231
0.0LysVal: 0.0 ± 0.0
1.639LysTrp: 1.639 ± 1.231
3.279LysTyr: 3.279 ± 2.462
0.0LysXaa: 0.0 ± 0.0
Leu
1.639LeuAla: 1.639 ± 1.231
0.0LeuCys: 0.0 ± 0.0
4.918LeuAsp: 4.918 ± 1.32
3.279LeuGlu: 3.279 ± 2.462
1.639LeuPhe: 1.639 ± 1.142
3.279LeuGly: 3.279 ± 2.462
1.639LeuHis: 1.639 ± 1.231
0.0LeuIle: 0.0 ± 0.0
1.639LeuLys: 1.639 ± 1.231
3.279LeuLeu: 3.279 ± 0.089
1.639LeuMet: 1.639 ± 1.231
1.639LeuAsn: 1.639 ± 1.142
0.0LeuPro: 0.0 ± 0.0
3.279LeuGln: 3.279 ± 2.283
1.639LeuArg: 1.639 ± 1.142
3.279LeuSer: 3.279 ± 2.462
8.197LeuThr: 8.197 ± 3.335
6.557LeuVal: 6.557 ± 0.179
0.0LeuTrp: 0.0 ± 0.0
1.639LeuTyr: 1.639 ± 1.231
0.0LeuXaa: 0.0 ± 0.0
Met
1.639MetAla: 1.639 ± 1.142
0.0MetCys: 0.0 ± 0.0
1.639MetAsp: 1.639 ± 1.142
6.557MetGlu: 6.557 ± 0.179
0.0MetPhe: 0.0 ± 0.0
1.639MetGly: 1.639 ± 1.142
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.639MetLys: 1.639 ± 1.231
1.639MetLeu: 1.639 ± 1.142
0.0MetMet: 0.0 ± 0.0
1.639MetAsn: 1.639 ± 1.142
1.639MetPro: 1.639 ± 1.231
1.639MetGln: 1.639 ± 1.142
1.639MetArg: 1.639 ± 1.142
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
4.918AsnAla: 4.918 ± 1.052
1.639AsnCys: 1.639 ± 1.231
1.639AsnAsp: 1.639 ± 1.231
1.639AsnGlu: 1.639 ± 1.231
0.0AsnPhe: 0.0 ± 0.0
6.557AsnGly: 6.557 ± 4.566
1.639AsnHis: 1.639 ± 1.231
3.279AsnIle: 3.279 ± 0.089
3.279AsnLys: 3.279 ± 2.283
3.279AsnLeu: 3.279 ± 2.283
0.0AsnMet: 0.0 ± 0.0
3.279AsnAsn: 3.279 ± 2.283
0.0AsnPro: 0.0 ± 0.0
1.639AsnGln: 1.639 ± 1.142
0.0AsnArg: 0.0 ± 0.0
3.279AsnSer: 3.279 ± 2.283
3.279AsnThr: 3.279 ± 2.283
3.279AsnVal: 3.279 ± 2.283
0.0AsnTrp: 0.0 ± 0.0
1.639AsnTyr: 1.639 ± 1.231
0.0AsnXaa: 0.0 ± 0.0
Pro
4.918ProAla: 4.918 ± 3.693
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
1.639ProGlu: 1.639 ± 1.231
1.639ProPhe: 1.639 ± 1.231
3.279ProGly: 3.279 ± 0.089
0.0ProHis: 0.0 ± 0.0
1.639ProIle: 1.639 ± 1.231
1.639ProLys: 1.639 ± 1.231
6.557ProLeu: 6.557 ± 2.194
1.639ProMet: 1.639 ± 1.142
1.639ProAsn: 1.639 ± 1.231
0.0ProPro: 0.0 ± 0.0
0.0ProGln: 0.0 ± 0.0
6.557ProArg: 6.557 ± 0.179
1.639ProSer: 1.639 ± 1.231
4.918ProThr: 4.918 ± 3.425
0.0ProVal: 0.0 ± 0.0
3.279ProTrp: 3.279 ± 0.089
1.639ProTyr: 1.639 ± 1.142
0.0ProXaa: 0.0 ± 0.0
Gln
4.918GlnAla: 4.918 ± 1.32
1.639GlnCys: 1.639 ± 1.231
0.0GlnAsp: 0.0 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
0.0GlnGly: 0.0 ± 0.0
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
1.639GlnLys: 1.639 ± 1.142
1.639GlnLeu: 1.639 ± 1.231
0.0GlnMet: 0.0 ± 0.0
1.639GlnAsn: 1.639 ± 1.142
1.639GlnPro: 1.639 ± 1.231
1.639GlnGln: 1.639 ± 1.142
0.0GlnArg: 0.0 ± 0.0
3.279GlnSer: 3.279 ± 2.462
3.279GlnThr: 3.279 ± 2.283
1.639GlnVal: 1.639 ± 1.142
0.0GlnTrp: 0.0 ± 0.0
1.639GlnTyr: 1.639 ± 1.142
0.0GlnXaa: 0.0 ± 0.0
Arg
4.918ArgAla: 4.918 ± 1.052
0.0ArgCys: 0.0 ± 0.0
3.279ArgAsp: 3.279 ± 2.462
4.918ArgGlu: 4.918 ± 3.693
1.639ArgPhe: 1.639 ± 1.231
6.557ArgGly: 6.557 ± 2.194
1.639ArgHis: 1.639 ± 1.231
6.557ArgIle: 6.557 ± 4.566
9.836ArgLys: 9.836 ± 2.104
0.0ArgLeu: 0.0 ± 0.0
0.0ArgMet: 0.0 ± 0.0
4.918ArgAsn: 4.918 ± 1.052
3.279ArgPro: 3.279 ± 0.089
0.0ArgGln: 0.0 ± 0.0
4.918ArgArg: 4.918 ± 3.425
9.836ArgSer: 9.836 ± 0.268
3.279ArgThr: 3.279 ± 0.089
6.557ArgVal: 6.557 ± 2.551
0.0ArgTrp: 0.0 ± 0.0
3.279ArgTyr: 3.279 ± 0.089
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
3.279SerAsp: 3.279 ± 0.089
3.279SerGlu: 3.279 ± 0.089
1.639SerPhe: 1.639 ± 1.231
9.836SerGly: 9.836 ± 0.268
0.0SerHis: 0.0 ± 0.0
6.557SerIle: 6.557 ± 0.179
3.279SerLys: 3.279 ± 0.089
0.0SerLeu: 0.0 ± 0.0
0.0SerMet: 0.0 ± 0.0
4.918SerAsn: 4.918 ± 1.32
3.279SerPro: 3.279 ± 0.089
1.639SerGln: 1.639 ± 1.231
6.557SerArg: 6.557 ± 2.194
3.279SerSer: 3.279 ± 2.283
8.197SerThr: 8.197 ± 5.708
6.557SerVal: 6.557 ± 4.566
0.0SerTrp: 0.0 ± 0.0
6.557SerTyr: 6.557 ± 2.194
0.0SerXaa: 0.0 ± 0.0
Thr
6.557ThrAla: 6.557 ± 4.566
1.639ThrCys: 1.639 ± 1.142
3.279ThrAsp: 3.279 ± 0.089
4.918ThrGlu: 4.918 ± 1.32
3.279ThrPhe: 3.279 ± 0.089
6.557ThrGly: 6.557 ± 4.566
0.0ThrHis: 0.0 ± 0.0
0.0ThrIle: 0.0 ± 0.0
4.918ThrLys: 4.918 ± 1.052
0.0ThrLeu: 0.0 ± 0.0
1.639ThrMet: 1.639 ± 1.142
3.279ThrAsn: 3.279 ± 0.089
3.279ThrPro: 3.279 ± 0.089
1.639ThrGln: 1.639 ± 1.142
0.0ThrArg: 0.0 ± 0.0
16.393ThrSer: 16.393 ± 11.416
1.639ThrThr: 1.639 ± 1.142
6.557ThrVal: 6.557 ± 2.194
1.639ThrTrp: 1.639 ± 1.231
3.279ThrTyr: 3.279 ± 2.283
0.0ThrXaa: 0.0 ± 0.0
Val
1.639ValAla: 1.639 ± 1.142
1.639ValCys: 1.639 ± 1.231
6.557ValAsp: 6.557 ± 0.179
0.0ValGlu: 0.0 ± 0.0
6.557ValPhe: 6.557 ± 0.179
8.197ValGly: 8.197 ± 3.782
1.639ValHis: 1.639 ± 1.231
1.639ValIle: 1.639 ± 1.142
6.557ValLys: 6.557 ± 2.551
0.0ValLeu: 0.0 ± 0.0
3.279ValMet: 3.279 ± 0.089
8.197ValAsn: 8.197 ± 5.708
1.639ValPro: 1.639 ± 1.142
1.639ValGln: 1.639 ± 1.142
0.0ValArg: 0.0 ± 0.0
3.279ValSer: 3.279 ± 0.089
8.197ValThr: 8.197 ± 0.963
4.918ValVal: 4.918 ± 1.052
0.0ValTrp: 0.0 ± 0.0
3.279ValTyr: 3.279 ± 0.089
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
1.639TrpCys: 1.639 ± 1.231
1.639TrpAsp: 1.639 ± 1.231
1.639TrpGlu: 1.639 ± 1.231
3.279TrpPhe: 3.279 ± 2.283
3.279TrpGly: 3.279 ± 2.462
1.639TrpHis: 1.639 ± 1.142
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
4.918TrpLeu: 4.918 ± 3.693
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
3.279TrpArg: 3.279 ± 0.089
0.0TrpSer: 0.0 ± 0.0
1.639TrpThr: 1.639 ± 1.231
1.639TrpVal: 1.639 ± 1.142
0.0TrpTrp: 0.0 ± 0.0
1.639TrpTyr: 1.639 ± 1.142
0.0TrpXaa: 0.0 ± 0.0
Tyr
6.557TyrAla: 6.557 ± 2.551
1.639TyrCys: 1.639 ± 1.231
3.279TyrAsp: 3.279 ± 0.089
1.639TyrGlu: 1.639 ± 1.231
0.0TyrPhe: 0.0 ± 0.0
3.279TyrGly: 3.279 ± 0.089
0.0TyrHis: 0.0 ± 0.0
1.639TyrIle: 1.639 ± 1.142
0.0TyrLys: 0.0 ± 0.0
1.639TyrLeu: 1.639 ± 1.142
1.639TyrMet: 1.639 ± 1.231
0.0TyrAsn: 0.0 ± 0.0
1.639TyrPro: 1.639 ± 1.142
0.0TyrGln: 0.0 ± 0.0
6.557TyrArg: 6.557 ± 2.194
0.0TyrSer: 0.0 ± 0.0
3.279TyrThr: 3.279 ± 2.283
0.0TyrVal: 0.0 ± 0.0
1.639TyrTrp: 1.639 ± 1.142
1.639TyrTyr: 1.639 ± 1.142
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (611 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski