Amino acid dipepetide frequency for Elderberry carlavirus A

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.564AlaAla: 3.564 ± 1.351
1.426AlaCys: 1.426 ± 1.233
1.069AlaAsp: 1.069 ± 0.578
2.851AlaGlu: 2.851 ± 1.213
2.138AlaPhe: 2.138 ± 0.566
4.277AlaGly: 4.277 ± 1.271
1.782AlaHis: 1.782 ± 0.603
3.564AlaIle: 3.564 ± 1.794
4.633AlaLys: 4.633 ± 2.262
8.909AlaLeu: 8.909 ± 4.143
1.426AlaMet: 1.426 ± 0.574
2.138AlaAsn: 2.138 ± 1.052
2.495AlaPro: 2.495 ± 1.435
1.426AlaGln: 1.426 ± 0.77
3.207AlaArg: 3.207 ± 1.295
5.346AlaSer: 5.346 ± 1.479
5.346AlaThr: 5.346 ± 1.4
4.989AlaVal: 4.989 ± 1.412
1.069AlaTrp: 1.069 ± 0.578
1.069AlaTyr: 1.069 ± 1.171
0.0AlaXaa: 0.0 ± 0.0
Cys
4.633CysAla: 4.633 ± 1.664
0.713CysCys: 0.713 ± 0.385
1.782CysAsp: 1.782 ± 2.329
1.426CysGlu: 1.426 ± 1.233
2.138CysPhe: 2.138 ± 1.155
2.495CysGly: 2.495 ± 1.079
0.356CysHis: 0.356 ± 1.075
2.495CysIle: 2.495 ± 0.966
0.713CysLys: 0.713 ± 0.385
1.426CysLeu: 1.426 ± 0.77
0.713CysMet: 0.713 ± 0.838
0.356CysAsn: 0.356 ± 0.767
1.069CysPro: 1.069 ± 1.016
0.713CysGln: 0.713 ± 1.089
2.138CysArg: 2.138 ± 0.566
2.495CysSer: 2.495 ± 1.129
2.138CysThr: 2.138 ± 0.962
3.207CysVal: 3.207 ± 0.856
0.0CysTrp: 0.0 ± 0.0
1.069CysTyr: 1.069 ± 0.917
0.0CysXaa: 0.0 ± 0.0
Asp
3.564AspAla: 3.564 ± 1.351
0.713AspCys: 0.713 ± 0.385
2.138AspAsp: 2.138 ± 0.815
4.633AspGlu: 4.633 ± 1.279
4.989AspPhe: 4.989 ± 1.743
3.207AspGly: 3.207 ± 1.34
1.069AspHis: 1.069 ± 0.629
1.426AspIle: 1.426 ± 2.607
2.495AspLys: 2.495 ± 2.08
4.633AspLeu: 4.633 ± 1.446
1.782AspMet: 1.782 ± 0.954
1.069AspAsn: 1.069 ± 1.016
1.782AspPro: 1.782 ± 0.603
1.069AspGln: 1.069 ± 0.578
2.495AspArg: 2.495 ± 1.418
2.138AspSer: 2.138 ± 0.936
1.426AspThr: 1.426 ± 1.092
4.277AspVal: 4.277 ± 1.185
0.713AspTrp: 0.713 ± 0.675
3.207AspTyr: 3.207 ± 1.412
0.0AspXaa: 0.0 ± 0.0
Glu
4.989GluAla: 4.989 ± 1.633
1.069GluCys: 1.069 ± 0.629
4.277GluAsp: 4.277 ± 1.271
6.415GluGlu: 6.415 ± 1.967
3.564GluPhe: 3.564 ± 1.889
4.633GluGly: 4.633 ± 1.664
1.069GluHis: 1.069 ± 0.578
4.633GluIle: 4.633 ± 1.375
3.564GluLys: 3.564 ± 0.942
7.484GluLeu: 7.484 ± 2.188
1.782GluMet: 1.782 ± 0.963
2.851GluAsn: 2.851 ± 1.132
3.92GluPro: 3.92 ± 1.695
1.782GluGln: 1.782 ± 0.675
3.92GluArg: 3.92 ± 1.376
6.058GluSer: 6.058 ± 1.217
1.069GluThr: 1.069 ± 0.578
3.92GluVal: 3.92 ± 1.154
0.0GluTrp: 0.0 ± 0.0
2.495GluTyr: 2.495 ± 0.592
0.0GluXaa: 0.0 ± 0.0
Phe
3.564PheAla: 3.564 ± 2.394
1.069PheCys: 1.069 ± 0.578
3.564PheAsp: 3.564 ± 1.206
4.277PheGlu: 4.277 ± 1.629
2.138PhePhe: 2.138 ± 0.566
3.92PheGly: 3.92 ± 2.688
1.426PheHis: 1.426 ± 1.349
3.564PheIle: 3.564 ± 1.079
3.564PheLys: 3.564 ± 1.484
7.484PheLeu: 7.484 ± 3.312
2.138PheMet: 2.138 ± 0.811
2.851PheAsn: 2.851 ± 1.132
1.069PhePro: 1.069 ± 0.578
1.426PheGln: 1.426 ± 0.641
1.069PheArg: 1.069 ± 0.629
4.989PheSer: 4.989 ± 1.625
2.851PheThr: 2.851 ± 1.113
3.564PheVal: 3.564 ± 1.496
0.0PheTrp: 0.0 ± 0.0
0.713PheTyr: 0.713 ± 0.981
0.0PheXaa: 0.0 ± 0.0
Gly
4.277GlyAla: 4.277 ± 1.185
2.138GlyCys: 2.138 ± 1.255
4.633GlyAsp: 4.633 ± 2.027
3.92GlyGlu: 3.92 ± 1.343
3.92GlyPhe: 3.92 ± 1.068
3.207GlyGly: 3.207 ± 2.037
0.356GlyHis: 0.356 ± 0.193
2.851GlyIle: 2.851 ± 1.329
5.346GlyLys: 5.346 ± 0.914
4.989GlyLeu: 4.989 ± 1.625
0.356GlyMet: 0.356 ± 0.193
3.207GlyAsn: 3.207 ± 1.943
1.069GlyPro: 1.069 ± 0.629
2.138GlyGln: 2.138 ± 0.914
6.058GlyArg: 6.058 ± 3.377
3.92GlySer: 3.92 ± 1.411
2.851GlyThr: 2.851 ± 1.206
2.851GlyVal: 2.851 ± 1.524
0.713GlyTrp: 0.713 ± 0.546
1.782GlyTyr: 1.782 ± 0.963
0.0GlyXaa: 0.0 ± 0.0
His
1.426HisAla: 1.426 ± 1.058
1.426HisCys: 1.426 ± 1.111
0.356HisAsp: 0.356 ± 0.193
0.356HisGlu: 0.356 ± 0.193
0.713HisPhe: 0.713 ± 0.385
1.069HisGly: 1.069 ± 2.153
0.356HisHis: 0.356 ± 0.193
0.713HisIle: 0.713 ± 0.675
1.426HisLys: 1.426 ± 0.574
4.277HisLeu: 4.277 ± 1.284
0.356HisMet: 0.356 ± 0.193
1.782HisAsn: 1.782 ± 1.396
0.713HisPro: 0.713 ± 0.385
0.713HisGln: 0.713 ± 0.675
1.426HisArg: 1.426 ± 1.961
4.633HisSer: 4.633 ± 1.473
0.713HisThr: 0.713 ± 0.981
1.426HisVal: 1.426 ± 0.977
0.0HisTrp: 0.0 ± 0.0
0.713HisTyr: 0.713 ± 0.385
0.0HisXaa: 0.0 ± 0.0
Ile
4.989IleAla: 4.989 ± 2.652
1.426IleCys: 1.426 ± 0.977
3.564IleAsp: 3.564 ± 1.076
5.702IleGlu: 5.702 ± 1.637
1.426IlePhe: 1.426 ± 0.574
3.92IleGly: 3.92 ± 1.102
1.426IleHis: 1.426 ± 1.318
4.633IleIle: 4.633 ± 1.448
3.92IleLys: 3.92 ± 1.117
3.564IleLeu: 3.564 ± 1.076
1.069IleMet: 1.069 ± 0.557
1.069IleAsn: 1.069 ± 0.526
1.782IlePro: 1.782 ± 1.125
1.426IleGln: 1.426 ± 0.641
2.851IleArg: 2.851 ± 2.093
4.277IleSer: 4.277 ± 1.924
4.989IleThr: 4.989 ± 3.465
4.989IleVal: 4.989 ± 2.238
0.356IleTrp: 0.356 ± 0.193
2.138IleTyr: 2.138 ± 0.815
0.0IleXaa: 0.0 ± 0.0
Lys
4.633LysAla: 4.633 ± 1.446
2.138LysCys: 2.138 ± 0.962
3.207LysAsp: 3.207 ± 1.41
4.277LysGlu: 4.277 ± 1.352
2.851LysPhe: 2.851 ± 1.132
3.564LysGly: 3.564 ± 0.919
2.138LysHis: 2.138 ± 1.835
2.851LysIle: 2.851 ± 1.234
3.207LysLys: 3.207 ± 1.306
8.553LysLeu: 8.553 ± 1.115
0.356LysMet: 0.356 ± 0.193
2.495LysAsn: 2.495 ± 0.966
3.92LysPro: 3.92 ± 1.154
2.851LysGln: 2.851 ± 0.909
3.564LysArg: 3.564 ± 1.967
4.277LysSer: 4.277 ± 3.409
3.92LysThr: 3.92 ± 1.247
3.92LysVal: 3.92 ± 1.666
0.356LysTrp: 0.356 ± 0.627
1.782LysTyr: 1.782 ± 0.675
0.0LysXaa: 0.0 ± 0.0
Leu
3.564LeuAla: 3.564 ± 1.415
2.851LeuCys: 2.851 ± 1.54
4.633LeuAsp: 4.633 ± 1.773
8.197LeuGlu: 8.197 ± 2.156
4.277LeuPhe: 4.277 ± 1.396
8.909LeuGly: 8.909 ± 1.706
2.138LeuHis: 2.138 ± 0.962
7.128LeuIle: 7.128 ± 2.246
8.197LeuLys: 8.197 ± 1.898
9.622LeuLeu: 9.622 ± 1.59
1.426LeuMet: 1.426 ± 0.892
5.346LeuAsn: 5.346 ± 2.888
6.771LeuPro: 6.771 ± 1.908
2.851LeuGln: 2.851 ± 0.909
4.277LeuArg: 4.277 ± 1.271
8.909LeuSer: 8.909 ± 6.512
4.989LeuThr: 4.989 ± 2.065
3.92LeuVal: 3.92 ± 2.118
0.0LeuTrp: 0.0 ± 0.0
2.495LeuTyr: 2.495 ± 3.184
0.0LeuXaa: 0.0 ± 0.0
Met
1.782MetAla: 1.782 ± 0.675
2.495MetCys: 2.495 ± 0.897
1.782MetAsp: 1.782 ± 1.746
0.356MetGlu: 0.356 ± 0.193
0.356MetPhe: 0.356 ± 0.193
0.713MetGly: 0.713 ± 0.546
0.0MetHis: 0.0 ± 0.0
0.713MetIle: 0.713 ± 0.385
1.426MetLys: 1.426 ± 0.574
1.782MetLeu: 1.782 ± 0.675
0.0MetMet: 0.0 ± 0.0
0.713MetAsn: 0.713 ± 1.089
1.426MetPro: 1.426 ± 0.977
1.069MetGln: 1.069 ± 0.578
2.851MetArg: 2.851 ± 1.234
1.069MetSer: 1.069 ± 0.578
0.713MetThr: 0.713 ± 0.385
0.356MetVal: 0.356 ± 0.193
0.356MetTrp: 0.356 ± 0.627
0.356MetTyr: 0.356 ± 0.627
0.0MetXaa: 0.0 ± 0.0
Asn
2.138AsnAla: 2.138 ± 0.815
0.713AsnCys: 0.713 ± 1.089
1.069AsnAsp: 1.069 ± 1.16
1.069AsnGlu: 1.069 ± 0.578
3.564AsnPhe: 3.564 ± 1.435
2.138AsnGly: 2.138 ± 0.811
1.426AsnHis: 1.426 ± 0.989
1.782AsnIle: 1.782 ± 0.675
1.782AsnLys: 1.782 ± 0.963
6.415AsnLeu: 6.415 ± 1.903
1.426AsnMet: 1.426 ± 0.801
1.426AsnAsn: 1.426 ± 0.977
2.495AsnPro: 2.495 ± 1.809
0.356AsnGln: 0.356 ± 0.193
3.564AsnArg: 3.564 ± 1.429
3.207AsnSer: 3.207 ± 1.306
1.782AsnThr: 1.782 ± 0.675
1.782AsnVal: 1.782 ± 1.434
0.713AsnTrp: 0.713 ± 0.546
3.564AsnTyr: 3.564 ± 1.339
0.0AsnXaa: 0.0 ± 0.0
Pro
2.851ProAla: 2.851 ± 1.575
2.495ProCys: 2.495 ± 0.949
2.851ProAsp: 2.851 ± 0.868
3.564ProGlu: 3.564 ± 2.107
0.713ProPhe: 0.713 ± 0.385
3.564ProGly: 3.564 ± 2.182
1.069ProHis: 1.069 ± 2.271
2.138ProIle: 2.138 ± 1.255
3.207ProLys: 3.207 ± 0.916
2.495ProLeu: 2.495 ± 1.202
0.713ProMet: 0.713 ± 1.386
1.426ProAsn: 1.426 ± 1.233
2.138ProPro: 2.138 ± 1.937
1.426ProGln: 1.426 ± 0.77
3.564ProArg: 3.564 ± 1.429
2.495ProSer: 2.495 ± 1.76
2.495ProThr: 2.495 ± 2.245
1.782ProVal: 1.782 ± 0.675
1.069ProTrp: 1.069 ± 0.578
0.713ProTyr: 0.713 ± 0.385
0.0ProXaa: 0.0 ± 0.0
Gln
1.426GlnAla: 1.426 ± 1.295
1.782GlnCys: 1.782 ± 0.975
1.069GlnAsp: 1.069 ± 0.578
2.495GlnGlu: 2.495 ± 0.949
1.069GlnPhe: 1.069 ± 0.578
2.138GlnGly: 2.138 ± 1.155
0.713GlnHis: 0.713 ± 0.385
1.426GlnIle: 1.426 ± 0.574
1.426GlnLys: 1.426 ± 0.77
3.564GlnLeu: 3.564 ± 1.242
0.0GlnMet: 0.0 ± 0.0
1.069GlnAsn: 1.069 ± 0.578
1.426GlnPro: 1.426 ± 1.092
0.356GlnGln: 0.356 ± 0.193
1.069GlnArg: 1.069 ± 1.235
3.564GlnSer: 3.564 ± 1.079
1.426GlnThr: 1.426 ± 0.641
1.069GlnVal: 1.069 ± 0.526
0.0GlnTrp: 0.0 ± 0.0
1.069GlnTyr: 1.069 ± 1.16
0.0GlnXaa: 0.0 ± 0.0
Arg
2.138ArgAla: 2.138 ± 2.14
2.851ArgCys: 2.851 ± 2.255
2.851ArgAsp: 2.851 ± 1.619
3.92ArgGlu: 3.92 ± 1.195
4.989ArgPhe: 4.989 ± 1.393
3.564ArgGly: 3.564 ± 1.415
1.782ArgHis: 1.782 ± 1.22
2.851ArgIle: 2.851 ± 2.223
2.851ArgLys: 2.851 ± 1.213
4.633ArgLeu: 4.633 ± 1.142
1.426ArgMet: 1.426 ± 0.977
5.346ArgAsn: 5.346 ± 0.896
1.069ArgPro: 1.069 ± 1.16
1.069ArgGln: 1.069 ± 1.334
3.92ArgArg: 3.92 ± 1.937
2.138ArgSer: 2.138 ± 0.962
2.851ArgThr: 2.851 ± 1.474
3.92ArgVal: 3.92 ± 1.164
1.069ArgTrp: 1.069 ± 0.578
3.564ArgTyr: 3.564 ± 1.363
0.0ArgXaa: 0.0 ± 0.0
Ser
3.207SerAla: 3.207 ± 1.34
2.851SerCys: 2.851 ± 0.902
2.495SerAsp: 2.495 ± 1.348
5.702SerGlu: 5.702 ± 2.186
6.058SerPhe: 6.058 ± 2.154
2.138SerGly: 2.138 ± 1.789
1.426SerHis: 1.426 ± 0.77
5.346SerIle: 5.346 ± 1.222
5.346SerLys: 5.346 ± 1.797
5.702SerLeu: 5.702 ± 3.334
0.713SerMet: 0.713 ± 0.546
3.92SerAsn: 3.92 ± 1.476
4.277SerPro: 4.277 ± 2.401
2.138SerGln: 2.138 ± 0.811
5.702SerArg: 5.702 ± 2.0
8.197SerSer: 8.197 ± 1.892
4.989SerThr: 4.989 ± 2.459
4.633SerVal: 4.633 ± 1.841
0.713SerTrp: 0.713 ± 0.385
1.782SerTyr: 1.782 ± 1.001
0.0SerXaa: 0.0 ± 0.0
Thr
3.92ThrAla: 3.92 ± 1.247
1.426ThrCys: 1.426 ± 1.537
1.426ThrAsp: 1.426 ± 1.058
2.851ThrGlu: 2.851 ± 0.675
6.415ThrPhe: 6.415 ± 2.356
4.277ThrGly: 4.277 ± 2.36
2.138ThrHis: 2.138 ± 0.811
2.851ThrIle: 2.851 ± 1.568
4.989ThrLys: 4.989 ± 3.18
3.92ThrLeu: 3.92 ± 1.102
0.713ThrMet: 0.713 ± 0.558
2.138ThrAsn: 2.138 ± 0.811
1.426ThrPro: 1.426 ± 0.77
1.782ThrGln: 1.782 ± 0.675
2.495ThrArg: 2.495 ± 1.47
3.92ThrSer: 3.92 ± 1.357
1.782ThrThr: 1.782 ± 1.675
1.069ThrVal: 1.069 ± 1.014
0.356ThrTrp: 0.356 ± 1.161
1.426ThrTyr: 1.426 ± 0.989
0.0ThrXaa: 0.0 ± 0.0
Val
3.564ValAla: 3.564 ± 2.151
1.426ValCys: 1.426 ± 0.574
4.633ValAsp: 4.633 ± 1.732
4.277ValGlu: 4.277 ± 1.849
1.782ValPhe: 1.782 ± 1.365
2.851ValGly: 2.851 ± 3.157
2.851ValHis: 2.851 ± 2.255
6.058ValIle: 6.058 ± 0.96
3.92ValLys: 3.92 ± 1.068
5.346ValLeu: 5.346 ± 1.599
2.138ValMet: 2.138 ± 1.052
1.426ValAsn: 1.426 ± 0.977
2.495ValPro: 2.495 ± 1.622
1.782ValGln: 1.782 ± 0.963
1.782ValArg: 1.782 ± 0.963
2.138ValSer: 2.138 ± 1.155
2.851ValThr: 2.851 ± 0.675
3.92ValVal: 3.92 ± 2.156
0.713ValTrp: 0.713 ± 0.546
1.782ValTyr: 1.782 ± 0.963
0.0ValXaa: 0.0 ± 0.0
Trp
0.713TrpAla: 0.713 ± 0.385
0.356TrpCys: 0.356 ± 0.193
0.356TrpAsp: 0.356 ± 0.627
0.356TrpGlu: 0.356 ± 0.767
1.069TrpPhe: 1.069 ± 0.578
0.0TrpGly: 0.0 ± 0.0
0.356TrpHis: 0.356 ± 0.193
0.0TrpIle: 0.0 ± 0.0
0.713TrpLys: 0.713 ± 0.385
1.426TrpLeu: 1.426 ± 0.77
0.0TrpMet: 0.0 ± 0.0
0.356TrpAsn: 0.356 ± 0.193
0.356TrpPro: 0.356 ± 1.161
1.069TrpGln: 1.069 ± 1.16
0.713TrpArg: 0.713 ± 1.255
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
1.069TrpVal: 1.069 ± 1.016
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.782TyrAla: 1.782 ± 1.674
0.713TyrCys: 0.713 ± 0.546
1.069TyrAsp: 1.069 ± 0.578
2.851TyrGlu: 2.851 ± 1.234
1.069TyrPhe: 1.069 ± 1.016
0.0TyrGly: 0.0 ± 0.0
0.713TyrHis: 0.713 ± 0.981
2.495TyrIle: 2.495 ± 2.867
2.138TyrLys: 2.138 ± 0.815
4.277TyrLeu: 4.277 ± 2.021
1.426TyrMet: 1.426 ± 0.574
1.426TyrAsn: 1.426 ± 0.77
1.069TyrPro: 1.069 ± 0.578
0.713TyrGln: 0.713 ± 0.385
2.138TyrArg: 2.138 ± 1.434
3.564TyrSer: 3.564 ± 1.879
2.495TyrThr: 2.495 ± 0.592
1.069TyrVal: 1.069 ± 0.526
0.713TyrTrp: 0.713 ± 1.089
2.138TyrTyr: 2.138 ± 3.054
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2807 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski